[HN Gopher] Human brain changes after first psilocybin use
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       Human brain changes after first psilocybin use
        
       Author : XzetaU8
       Score  : 31 points
       Date   : 2024-10-15 19:52 UTC (3 hours ago)
        
 (HTM) web link (www.biorxiv.org)
 (TXT) w3m dump (www.biorxiv.org)
        
       | ericmcer wrote:
       | I took a fair number of trips when I was 16 and I think it
       | literally brought my consciousness online. There was a pretty
       | stark contrast between the me before who who just wanted to play
       | video games and hang out with friends, and the me after who was
       | overwhelmed by natural beauty and my smallness in relation to the
       | vastness around me. It might have been responsible for the next
       | 5+ years of my life where I shirked school/career in favor of
       | delving pretty deep into hallucinogens and a hippy type lifestyle
       | in search of some "Truth".
       | 
       | I don't know if it was just timing and it jump started a natural
       | part of aging, or if it triggered something that would not have
       | occurred otherwise. Either way it definitely did a number on my
       | 16 year old brain, still unsure if it was a net positive or
       | negative.
       | 
       | The sad part is they don't have such a profound effect on me
       | anymore, it can still be pretty interesting but the life altering
       | trips seem to be reserved for the first few times. My only
       | expectation from them now is to feel nice and have some pleasant
       | visuals. I don't approach it seeking some lesson or greater
       | truth, just have a nice time, which is maybe the final lesson
       | lol.
        
         | namaria wrote:
         | McKenna would argue that's how apes became humans
        
         | sameoldtune wrote:
         | my layman viewpoint is that psychedelics make things that
         | seemed immutable more...mutable. Everyone has some short list
         | of things they are endlessly hung up on. Mushrooms might make
         | you realize there are more viewpoints and more options.
         | 
         | But after you've taken them a few times, there isn't so much
         | resistance. It's just a goofy light feeling for a few hours.
         | Chasing that feeling when you first took them and realized that
         | "borders are just like, made up man!" is just like chasing any
         | other high.
        
         | ne0flex wrote:
         | >I don't approach it seeking some lesson or greater truth, just
         | have a nice time, which is maybe the final lesson lol. I relate
         | to this a lot. After a friend died in 2020, I started down that
         | rabbit hole increasing dosages for look "perspective" or
         | "truth" that ended up cumulating into an overdose and an
         | overnight hospital stay. At that point, I realized that going
         | into these things searching for something / using as a coping
         | mechanism is fruitless and it's a more "enjoy the journey" type
         | of thing. I was hoping for an epiphany that would set me on
         | some steel-willed journey, but that never came.
        
           | mistermann wrote:
           | > At that point, I realized that going into these things
           | searching for something / using as a coping mechanism is
           | fruitless
           | 
           | One failure does not prove something is not possible.
           | 
           | When under the influence, have you ever encountered knowing
           | that the reality we experience here is not what it seems to
           | be? Bringing these things back (especially in a persistent
           | manner) is tough, but most people can recall the phenomenon
           | abstractly.
        
             | Jerrrry wrote:
             | Lol depersonalization and derealization and dissociation
             | and DMT elves are awesome, but the reason the ideas are so
             | fleeting, consulate, vague... yet determinate; is because
             | they are completely fabricated illusions of abstract
             | collective unconscious archetypes.
             | 
             | They are no more or less real than the rest of our
             | artifacts from evolution.
             | 
             | But attempting to give any more credence to these phenomena
             | than to dreams or intrusive thoughts is essentially a
             | dragon hunt of sorts.
        
           | hipshaker wrote:
           | Seems to me like you did learn something. That you were not a
           | steel-willed journyman prone to epiphanies. I know it may
           | sound silly, but there is some true value to that. Who's to
           | say those experiences didn't speed up something you may
           | orherwise would have spent even more time and resources on
           | pursuing. Disclaimer: I of course do not know you or anything
           | about you except for your comment.
        
           | bamboozled wrote:
           | Once you get the message, hangup
        
       | 486sx33 wrote:
       | Personally this drug in not real heavy doses helped me tackle
       | some issues in my life when I was younger that helped me become
       | more psychologically free. I recall having a bonfire on my lawn
       | in the middle of the day while burning my taxes. Sounds weird but
       | it did help
        
       | hipshaker wrote:
       | Psilocybin, MDMA and Salvia divinorum have had a profound effect
       | on my life and the person I am today. Of course it's impossible
       | to say who I would be, had I not tried these. Has it been for the
       | better? Maybe. For the worse? Maybe. I do know that they are
       | experiences I would not want to be without. They taught me a
       | great desl about myself and helped shape my perception of the
       | inner and outer world surrounding me. Am I smarter and more
       | enlightened, probably not. May be I even shaved off an IQ point
       | or two in the proces. But having my reality altered, even totally
       | disintegrated (salvia) certainly paved the way for acceptance of
       | other states of mind that people may exist in. This is very
       | valuable to me, as it helped break down a black and white coccon
       | I see many people live in (some break free by orher means, some
       | never escape it). To me, it was bungee jumping for the mind but
       | from the comfort of my own home. It certainly has helped me take
       | on and be comfortable with opposing viewpoints, being very
       | tolerant in general and able to reach further into the corners of
       | my mind. It's been decades since those first jumps, but the
       | effects will last me a lifetime.
        
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