[HN Gopher] Metabolic byproduct of anaerobic exercise helps canc...
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       Metabolic byproduct of anaerobic exercise helps cancer cells resist
       chemotherapy
        
       Author : assadk
       Score  : 9 points
       Date   : 2024-08-23 22:27 UTC (33 minutes ago)
        
 (HTM) web link (www.nature.com)
 (TXT) w3m dump (www.nature.com)
        
       | melling wrote:
       | This is all I can read. Does the paper imply that any exercise is
       | bad?
       | 
       | " Lactate helps cancer cells resist chemotherapy The molecule
       | lactate is a waste product of the metabolism of sugar without
       | oxygen -- a metabolic pathway preferentially used by cancer cells
       | to generate their energy. Metabolomics analysis reveals that
       | lactate in tumour cells promotes resistance to chemotherapy, and
       | sheds light on the molecular mechanism that underlies this
       | unexpected role of lactate in cancer"
        
         | mrcode007 wrote:
         | https://www.nature.com/articles/s41586-024-07620-9.pdf
        
         | OutOfHere wrote:
         | > Does the paper imply that any exercise is bad?
         | 
         | How did you leap from (anaerobic) exercise to just exercise?
         | It's quite the leap.
        
           | melling wrote:
           | I guess I didn't process it.
           | 
           | Just got back from a 3 mile walk and had my first
           | chemotherapy yesterday. A little panic set in. Sounds like
           | walking is still good. Thanks
        
         | adrian_b wrote:
         | Lactate accumulates in the body only during a high intensity
         | exercise, which generates lactate faster than it can be
         | consumed by oxidation (like a sprint for up to 400 m).
         | 
         | When the intensity of an exercise is low enough that you could
         | sustain it for much more than a few minutes continuously, there
         | should be no increased amount of lactate in the body.
        
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       (page generated 2024-08-23 23:00 UTC)