[HN Gopher] Toxic people could become a reality, scientists rese...
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       Toxic people could become a reality, scientists researching snake
       venom say
        
       Author : booleandilemma
       Score  : 61 points
       Date   : 2021-03-30 20:06 UTC (2 hours ago)
        
 (HTM) web link (www.irishexaminer.com)
 (TXT) w3m dump (www.irishexaminer.com)
        
       | airhead969 wrote:
       | There are some venomous mammals.
       | 
       | Coincidentally, there was a posting today about it earlier.
       | 
       | https://news.ycombinator.com/item?id=26635391
        
       | k__ wrote:
       | Aren't human bites toxic for humans already?
        
         | malwarebytess wrote:
         | >Scientists have found the genetic foundation needed for oral
         | venom to evolve is present in both reptiles and mammals, and
         | said their study shows the first concrete evidence of a link
         | between venom glands in snakes and salivary glands in mammals.
         | 
         | You're talking about oral bacteria. Article is talking about
         | actual venom.
        
         | gruez wrote:
         | They are?
        
           | arthurcolle wrote:
           | Yes. Mouth bacteria and viruses in human mouths are the
           | factors. Not something I'd be super worried about in general.
           | (That being said, I was bitten by a psycho when I was 8 and
           | didn't die so that's cool.)
           | 
           | https://www.mayoclinic.org/first-aid/first-aid-human-
           | bites/b....
        
           | jimbob45 wrote:
           | Yeah, if you get bitten by a homeless individual (or any
           | individual), you need to be rushed to the ER to ensure you
           | don't get dangerous bacteria in your bloodstream running
           | free.
           | 
           | Edit: there appears to be debate over my wording but just
           | please don't miss the lesson here: seek medical attention if
           | bitten.
        
             | louwrentius wrote:
             | > if you get bitten by a homeless individual (or any
             | individual)
             | 
             | I think that's quite a bad remark. I believe you can do
             | better.
        
             | airhead969 wrote:
             | Bruh. Poverty-shaming ain't cool.
        
               | xwdv wrote:
               | Except it's true, and could save someone's life. If a
               | homeless person with bad dental hygiene were to bite you
               | deep enough to sink their teeth into a blood vessel you
               | might not live happily ever after, you're almost
               | certainly looking at an infection if left untreated.
        
               | eeZah7Ux wrote:
               | Then say "person with bad dental hygiene".
               | 
               | Don't single out homeless people: one can have bad dental
               | hygiene without being homeless.
               | 
               | (speaking about toxic language...)
        
               | libria wrote:
               | If _any_ person were to bite you. I 'm not aware of data
               | that suggests significant variance in mouth bacteria
               | among impoverished vs affluent, i.e. if Bezos were to
               | bite me right now, I'd still go to the ER. Anyway, I'd
               | guess biting is more common among preschoolers than
               | homeless people.
        
               | dumpsterdiver wrote:
               | Referencing the realities and plight of homeless folks is
               | not shaming. Should we instead not talk about the fact
               | that they don't have running water to brush their teeth
               | with?
               | 
               | When you brush aside the truth in order to be politically
               | correct it only hurts those who are most vulnerable. Our
               | sensibilities will survive, but in the meantime an
               | absessed tooth can absolutely prove fatal to anyone not
               | willing or able to seek treatment (guess who).
               | 
               | Being homeless comes with a lot of bad things, and one of
               | those things is exposure to diseases that are passed upon
               | skin contact. Pretending that homeless folks are just
               | "normal folks like the rest of us" truly does them a
               | disservice. They need help, and by pretending that they
               | don't (or rather, by shunning such conversations out of
               | "politeness") we are hurting them for the benefit of our
               | own conscience. We are only being polite to our own
               | sensibilities when we ignore the plight of homeless
               | people, and pretend to put them on equal footing when
               | they are truly nowhere close. Instead of taking personal
               | offense to the statement I just made, think about them
               | instead. It's become very tiring to see people "stand up"
               | for others, when they are really only standing up to make
               | themselves feel better about mostly ignoring the problem.
        
           | Teknoman117 wrote:
           | They are probably talking about how deep bites from humans
           | have a high chance of becoming infected if not treated.
           | 
           | Our mouths are quite dirty in general.
        
       | airhead969 wrote:
       | With the advent of genetic design and designer babies, I don't
       | see how ethics alone can prevent "soldier" and "assassin"
       | specialists from being born that have all sorts of enhancements.
        
         | ravenstine wrote:
         | What if that's better? Everyone could have a purpose and not
         | need to search for it, often in futility.
        
           | dillondoyle wrote:
           | I've thought about it and there are for sure small physical
           | things I'd love to change from birth to benefit my
           | sport/hobbies.
           | 
           | But the problem is parents would be making that decision. Or
           | in this case a dictator's military haha.
           | 
           | There are already hover parents living vicariously through
           | sports, music, chess whatever.
           | 
           | I can imagine this going to extremes with parents making
           | these forever physical decisions.
           | 
           | Elite athletes can chose to endanger their health for the
           | sport they love.
           | 
           | But I'm not sure about the ethics of a parent deciding to say
           | give lower resting heart rates/higher vo2 max with cycling in
           | mind, even though it could be deadly slow.
        
           | brendoelfrendo wrote:
           | What if they aren't interested in, or worse, resent their
           | "purpose," but can't change it due to some societal and
           | genetic pigeon-holing? That sounds worse than searching for a
           | purpose for myself, tbh.
        
           | sneak wrote:
           | There's no indication that someone's genetically-specialized
           | vocation would be something that that person would personally
           | be interested in pursuing. There are numerous counterexamples
           | of a person's choices in life being orthogonal or even
           | entirely opposed to their parents' hopes and desires for
           | their life.
           | 
           | I wouldn't be that into assassination as a vocation even if I
           | had superpowers that made me an extremely good assassin, for
           | example.
           | 
           | Obligatory: https://en.wikipedia.org/wiki/Brave_New_World
        
             | hayst4ck wrote:
             | It sounds like you are very much in the party of nurture
             | over nature. Either could result in a person "being into"
             | something. You are taking your genetics and your upbringing
             | and projecting them onto future scientific possibilities,
             | and I don't think that makes much sense.
             | 
             | What if you sequence the great computer scientists and
             | average ones and find some genes that really make a
             | difference? What if you sequence sociopaths and discover a
             | series of genes that correlate heavily with it? Sexuality,
             | flight or flight responses, physical aptitude, mental
             | aptitude.
             | 
             | We've spent millennia doing a less advanced form of this on
             | dogs, can you honestly say a lot of these dogs we've bred
             | for specific jobs aren't "into them"?
        
               | sneak wrote:
               | > _It sounds like you are very much in the party of
               | nurture over nature._
               | 
               | No, this entirely different to that. I'm saying that a
               | person's physical attributes are orthogonal to that
               | person's personality. I'm not discussing if their
               | personality is a result of nature or nuture, just the
               | fact that if you're, for example, physically predisposed
               | to, say, being able to grow large muscles, that has no
               | bearing whatsoever on whether or not you are personally
               | interested in, say, competitive weightlifting (regardless
               | of whether or not that personal interest (or lack
               | thereof) is a result of nature or nuture).
               | 
               | The fact that you are predisposed to be able to grow
               | large muscles is obviously nature; the circumstances
               | surrounding whether or not you actually _do_ grow large
               | muscles is open to the nature /nurture debate, as well as
               | the psychological manifestations that might lead one to
               | engage in (or avoid) bodybuilding, competition, et c.
        
           | JellyBeanThief wrote:
           | Not everyone wants a purpose, many people who have purposes
           | imposed on them by parents or other authority figures later
           | reject them, and not everybody who does want a purpose thinks
           | of it as a search.
           | 
           | Purposes are tools humans use to give their own lives
           | meaning, if they desire. Purposes should serve humans, not
           | the other way around.
        
           | SerLava wrote:
           | That's horrible. I think you don't know what a meaningful
           | life is.
        
         | simcop2387 wrote:
         | I think we'll be fine as long as nobody names one of them Khan
         | Noonien Singh. But seriously, I agree, someone will do it and
         | then it'll be another multi-armed race.
        
           | airhead969 wrote:
           | Anti-critters crawling into ears armor.
           | 
           | I want a prehensile tail and feet. Maybe some gene therapy
           | can make that happen to grow and remodel existing tissue?
        
         | SamoyedFurFluff wrote:
         | It would take at least several years of development to create
         | one vaguely effective venomous human assassin, with probably
         | over a decade of development until the human developed vaguely
         | enough dexterity to actually assassinate people. Unless we
         | figure out a way to make humans grow faster at scale? I've
         | always felt that enhancing human genetics to make them into
         | weapons strikes me as more expensive and less scalable than
         | inventing machinery that humans can use as weapons.
         | 
         | What would be more scalable- a human born venomous or the
         | ability to install a venom gland in a human sinus, replacing at
         | least one tooth?
        
           | SubiculumCode wrote:
           | yes. And in the meantime, simple drones that fling poisoned
           | darts, or even toss venomous snakes, is much more feasible
           | than mutant ninja warriors.
        
             | jetbooster wrote:
             | Biting people isn't particularly discreet, and a person
             | that gets captured can't dispose of a gland. A similarly
             | deadly poison in the tip of a mundane item that a person
             | might reasonably be carrying seems much more practical,
             | much more likely to succeed, and much more likely to remain
             | undetected
        
         | afarrell wrote:
         | I think raising a child is a lot more effort than giving a
         | trained operative weaponized dentures.
        
           | warent wrote:
           | LOL this is basically the Juicero of weaponizing humans.
           | Absurdly over-engineered solution searching for a problem.
        
         | mc32 wrote:
         | How do they ensure being venomous to others while remaining
         | immune themselves?
        
         | pantalaimon wrote:
         | Why bother with super soldiers when you can have robots and
         | drones?
        
       | mgarfias wrote:
       | Toxic headline is toxic.
        
         | libria wrote:
         | Yeah, obvious clickbait. An animal is venomous, the venom is
         | toxic (a toxin). I wouldn't call a cobra "toxic" unless it was
         | constantly starting flamewars on Facebook.
        
           | dumbfoundded wrote:
           | Apparently you haven't heard of Cobra Kai
        
       | mrfusion wrote:
       | How would laws evolve to handle this?
        
         | temp0826 wrote:
         | I'll try adding it when I have to update the registration for
         | my fists as lethal weapons.
        
           | airhead969 wrote:
           | My tongue is lethal, but not how you think.
           | 
           | Edit: SMH. I end up spraying more than I say.
        
           | anigbrowl wrote:
           | Some police departments already classify body parts as
           | 'personal weapons'. I recall a case in california a few years
           | ago where a pre-teen was mistakenly arrested over an alleged-
           | but-not-remotely-plausible resemblance to a burglary suspect.
           | 
           | I can't remember the exact location or details sufficiently
           | well to look it up but I remember the bit about personal
           | weapons as an odd fact that jumped out at me from a copy of
           | the arrest report.
        
         | wincy wrote:
         | I'm not sure they'd even need to evolve, it's already illegal
         | to bite people. It probably wouldn't even need to be made more
         | illegal than it already is.
        
           | mrfusion wrote:
           | A single bite would be deadly though. Could they force you to
           | produce an anti-venom?
        
             | airhead969 wrote:
             | It would be a murder charge if they died, so the suspect's
             | interests are probably to comply and produce venom for
             | anti-venom.
             | 
             | Probably yes. Forced collection of blood samples for
             | substance testing and cheek swabs for DNA collection.
        
             | pasquinelli wrote:
             | a single bite can kill now.
        
           | type0 wrote:
           | It's good to know if you ever end up in a Mad TV Playstation
           | 3 situation.
        
       | simonhamp wrote:
       | There are already toxic people. And they don't even need genetic
       | manipulation to achieve it.
       | 
       | The good news is, they weren't born that way and they can change.
        
         | echelon wrote:
         | > The good news is, they weren't born that way and they can
         | change.
         | 
         | Not according to some members of cancel culture. Once you've
         | wronged someone, your career is over.
        
           | p1necone wrote:
           | Name 5 people whose careers were ended because of "cancel
           | culture".
        
         | anigbrowl wrote:
         | _The good news is, they weren 't born that way and they can
         | change._
         | 
         | Debatable. See
         | https://advances.sciencemag.org/content/2/8/e1600451 and
         | particularly the supplementary materials about age
         | distribution. I held the same opinion as you and was quite
         | surprised by these results.
        
       | platty wrote:
       | I knew a ton of toxic people in high school, can't believe the
       | research is catching up
        
         | colineartheta wrote:
         | Look at this guy, only a ton in high school. If only we could
         | all be so luck...
        
       | namenotrequired wrote:
       | This detail intrigues me:
       | 
       | > "...then in a few thousand years, we might encounter venomous
       | mice."
       | 
       | A female mouse can give birth at the age of two and a half
       | months. In a few thousand years, you can have some 10 000
       | generations.
       | 
       | Would it really take 10 000 generations for mice to become
       | venomous?
        
         | dumbfoundded wrote:
         | I don't think there's a good enough understanding of genetics
         | to know how many generations. I'm guessing the estimate of a
         | few thousand years was a complete guess. Many things impact the
         | timing and these systems are chaotic. Even selective breeding
         | is fairly uncertain. I don't know if geneticists could predict
         | how many generations it would take if we selectively breed gray
         | wolves to look like pugs.
        
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       (page generated 2021-03-30 23:00 UTC)