https://www.irishexaminer.com/world/arid-40254002.html X Sign in Subscribe My Account Sign out Irish Examiner Logo * * Sign in Subscribe My Account Sign out * news Ireland Munster Politics Court & Crime Spotlight World * sport GAA Soccer Rugby Racing Golf Other * lifestyle Health & Wellbeing Food & Recipes Arts & Culture Fashion & Beauty Relationships Travel People Celebrity Motoring * business Economy Companies Munster Business Farming Technology * property Residential Commercial Planning Development & Construction Home & Outdoors * opinion Columnists Comment & Analysis Our View Your View * Podcasts Ask Audrey Mick Clifford Weekend GAA Soccer Rugby * MORE Family Notices Jobs MyHome.ie Horoscopes Photosales Newspaper books Podcasts Subscribe ePaper Newsletters Competitions Place ad Archive Contact Us * [ ] * * Ireland Munster Politics Court & Crime Spotlight World * GAA Soccer Rugby Racing Golf Other * Health & Wellbeing Food & Recipes Arts & Culture Fashion & Beauty Relationships Travel People Celebrity Motoring * Economy Companies Munster Business Farming Technology * Residential Commercial Planning Development & Construction Home & Outdoors * Columnists Comment & Analysis Our View Your View * Ask Audrey Mick Clifford Weekend GAA Soccer Rugby * Family Notices Jobs MyHome.ie Horoscopes Photosales Newspaper books Podcasts Subscribe ePaper Newsletters Competitions Place ad Archive Contact Us * news * sport * lifestyle * opinion Toxic people could become a reality, scientists researching snake venom say Mice and even humans have the potential to become venomous - giving a new meaning to the description of someone as a toxic person - according to research Toxic people could become a reality, scientists researching snake venom say Scientists used venom glands collected from the Taiwan habu snake (OIST/Steven Aird/PA) Tue, 30 Mar, 2021 - 06:41 Aine Fox, PA Mice and even humans have the potential to become venomous - giving a new meaning to the description of someone as a toxic person - according to research. Scientists have found the genetic foundation needed for oral venom to evolve is present in both reptiles and mammals, and said their study shows the first concrete evidence of a link between venom glands in snakes and salivary glands in mammals. The research, published in the PNAS journal, indicates that while neither humans or mice are venomous currently, our genomes have the potential under certain ecological conditions. Study author Agneesh Barua joked: "It definitely gives a whole new meaning to a toxic person." He described venom as "a cocktail of proteins" used by animals to immobilise and kill prey, as well as for self-defence. For their research, instead of focusing on genes that code for the proteins that make up the toxic mixture, scientists from the Okinawa Institute of Science and Technology Graduate University (OIST) and the Australian National University looked for genes that work alongside and interact with the venom genes. They used venom glands from the Taiwan habu snake - a pit viper found in Asia - and identified about 3,000 of these "co-operating" genes, noting they played important roles in protecting the cells from stress caused by producing lots of proteins. The researchers also looked at the genomes of other creatures including mammals like dogs, chimpanzees and humans, and found they contained their own versions of such genes. Having investigated the salivary gland tissues within mammals, they saw the genes had a similar pattern of activity to that seen in snake venom glands - therefore concluding that salivary glands in mammals and venom glands in snakes share an ancient functional core. Mr Barua said: "Many scientists have intuitively believed this is true, but this is the first real solid evidence for the theory that venom glands evolved from early salivary glands. "While snakes then went crazy, incorporating many different toxins into their venom and increasing the number of genes involved in producing venom, mammals like shrews produce simpler venom that has a high similarity to saliva." He said experiments in the 1980s had shown that male mice "produce compounds in their saliva that are highly toxic when injected into rats". He added: "If under certain ecological conditions, mice that produce more toxic proteins in their saliva have better reproductive success, then in a few thousand years, we might encounter venomous mice." He added that although it is unlikely, if the right ecological conditions ever existed, humans also have the potential to become venomous. 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