Posts by pmcdunnough@gigaohm.bio
(DIR) Post #AjXyBwLjlN1NwMVHYO by pmcdunnough@gigaohm.bio
2024-06-18T22:50:16.584516Z
0 likes, 0 repeats
He lost his tenured job as a Professor of microbiologist at the University of Waterloo, which was strange for Canada. He & quite a few other biology academic in Canada risked a lot trying to provide a counter narrative to Public Heath which has been out of control.
(DIR) Post #AjXyByoAccxBZ7p19M by pmcdunnough@gigaohm.bio
2024-07-02T07:35:10.672538Z
0 likes, 0 repeats
I don’t know if Canada has always been like this. It didn’t seem to have so many thinking their solution to life was the only way. Social media has provided us with a million Voltaire’s. I suppose we should be thankful for that, if we could only find the needle in the haystack.My coma?
(DIR) Post #AjXyC0Xw9x9mxMF57o by pmcdunnough@gigaohm.bio
2024-07-02T21:15:01.071824Z
0 likes, 0 repeats
I don’t know who you are, or what you are saying. I’ve lived 73 years in Quebec then Canada and have observed the transition from live human to human interactions in very trying times to the fake intellectuals with superficial knowledge and google search engine skills. The reference to delusional nostalgia is not for me to judge, nor you since you have no idea who I am. I have lived my life and will not accept some anonymous computer hinting that I was unaware of what I experienced.
(DIR) Post #AjXyC1wQyMLXHci9wm by pmcdunnough@gigaohm.bio
2024-07-03T03:30:52.129475Z
0 likes, 0 repeats
Thank you for the summary.
(DIR) Post #AjqdAsVGAiqegfqg6q by pmcdunnough@gigaohm.bio
2024-07-12T07:35:58.715193Z
0 likes, 0 repeats
Can anyone provide an idiot proof description of the login process? I can login to gigaohm.bio, but that login doesn’t appear to carry over to the other various entities.Thanks…
(DIR) Post #AlyZPctOjzzOIGsEHQ by pmcdunnough@gigaohm.bio
2024-09-13T03:11:52.884385Z
0 likes, 0 repeats
Still trying to read the map. I have been able to log in here, not anywhere else which is fine. I can find twitch, the home page of gigaohmbiological ( sometimes) but can’t log in. Now J.Couey mentioned a list of pdf’s on his homepage related to Bio 101. These are books that seem hard to find. Where is that page? Maybe someone can draw me a map to navigate to… Thanks…philip
(DIR) Post #AlyZR5FUnX8qWru9Dc by pmcdunnough@gigaohm.bio
2024-09-13T21:13:27.690421Z
0 likes, 0 repeats
I login on twitch, login on gigaohm.bio, login now on gigaohmbiological.com, login I think on SendOwl, etc… I no longer know who I am or whether I am different people all over the place. I think I am just burnt out and not able to handle the irreducible complexity of 5 or so sources which if you master one doesn’t lead to knowing about the other. Not the fault of @jjcouey of course, but rather frustrating with the increasing complexity of the internet, and even my Apple products which used to be simple.
(DIR) Post #ApwvYUtQ9vrUSVmtsW by pmcdunnough@gigaohm.bio
2025-01-10T01:52:23.710896Z
0 likes, 0 repeats
So just to be clear. What is meant by a pandemic? What is meant by RNA cannot pandemic? When measles hits a town and we all went and caught it, did we catch the same identical virus? Some people seem to feel measles is not your usual RNA virus. Am confused. Does the measles virus remain the same from year to year? If not, what’s different about it.
(DIR) Post #Astscb37nFOyIti0Xo by pmcdunnough@gigaohm.bio
2025-04-04T02:30:16.518256Z
0 likes, 0 repeats
Why is Dr Battacharyia dangerous?
(DIR) Post #AstscczeZ7oUKi6GPY by pmcdunnough@gigaohm.bio
2025-04-04T06:46:12.887011Z
1 likes, 0 repeats
I did not sign that for technical issues involving isolating healthy people & basic treatment of those sick,mostly based on what I consider a misunderstanding of randomization . The GBD was not feckless imho and calling Professors Gupta and Martin Kulldorff useless academics is outrageous. Easy to do anonymously I suppose.Not many fully grasped Jay Couey’s coverage of the infectious cycle, clones, etc… Not exactly simple material. People can only try their best. I disagree with your views completely.
(DIR) Post #AtNp9cneJtZKkODGam by pmcdunnough@gigaohm.bio
2025-04-23T05:22:06.766126Z
1 likes, 0 repeats
Definitely interesting. Am not a fan of randomization nor blinding for that matter, although blinding makes sense if knowing what one got affects behavior in a sequential design. Just take a large bunch and divide them into 2 comparable groups. Give group 1 the V, 2 saline. Then 4 weeks later 1 saline and 2 vaccine. Blind if you want of course which would please those who insist on it. The advantage of not blinding is you can follow along and see if something happens and save those who got the saline.Neat idea. Weird that something like that has never been done. Thanks for bringing it all up.
(DIR) Post #B0IDNXMxA7SGZeuyNU by pmcdunnough@gigaohm.bio
2025-11-14T23:45:44.088295Z
0 likes, 0 repeats
Assume, which is not obvious, that probability actually means something. It is currently used for extrapolating from small numbers of observations to whole populations. Examples include sequences with many restricted permutations, large populations of humans where opinions on whatever is of interest. The sampling of humans to guess opinions seems to work. Here’s why. Imagine a city with a large population, each with an identical opinion. In that case selecting any person and getting his opinion will allow you to extrapolate perfectly to the whole city. This is never the case of course but the trick is to divide the population into subsets of similar people ( neighbors, basketball players, etc…) in a way that people within each subset think alike. Now you only need 1, or to be safe, a few observation(s) from each subset to extrapolate to the whole population. This is stratification. Your extrapolation will only be as good as you are in identifying subsets of like minded people. Some experienced pollsters are quite adept at this. Notice you aren’t randomizing anything. People randomize out of a convenient way of generating numbers, amongst other reasons which involve reasons I can’t fully describe.In short, you can accurately extrapolate to a whole population only if you are good at identifying similar subsets. Within each of those subsets you can pick anyone you want for an opinion.Somehow there is a link to this way of viewing inference in finite populations to the sequencing issue, but that link is elusive to me. The Bayes folks will convince you with simple formulae but they have a problem in that uninformative priors don’t work in many situations without violating the rules of probability due to Kolmogorov. The same problem happen with Fisher’s fiducial inference and the extension of Fisher’s attempt by Fraser in the structure of inference. Fisher’s emphasis in hypothesis testing was on p values which is a type of random contrapositive ( proof by contradiction) and the medical world has fully embraced this approach.Sorry for the seemingly unrelated topic, but I suspect it is relevant to sequencing, AI claims and even the identification of pathogens under incomplete observation. The 2 pieces which have bothered me for quite a while are the RNA infinite persistence in a pathogenic form similar across different regions & the identification of a sequence from a partial observation of it.The final unknown that jjcouey has mentioned is the IM issue. This seems complicated. My impression is that IM vaccines do sometimes work, but when given to millions you will always have some unfortunate problems. As far as transfection goes I am curious why I know noone ( maybe one but they deny it now) who were harmed by them. It’s also true that I know noone who died in the recent pandemic, except 2 extended family members who were likely killed in the USA by hospital protocols. We are talking the elderly here so this should not be the case.Again, sorry for the confusing post but imho there is a larger link to statistics & our current mess than meets the eye.
(DIR) Post #B0IDNZBgOzd0DHf05Y by pmcdunnough@gigaohm.bio
2025-11-15T20:37:39.776070Z
0 likes, 0 repeats
Thank you. I don’t know if you could find this in any one place. The usual sources would likely present a simplified version of typical calculations used for specific problems, jumping over the tricky issues which underline the methods. If you have a good math background Silvey’s book on Statistical Inference will provide a short discussion of many topics, Cox & Hinkley is a somewhat dated overview of standard math stats and Cox’s texts on inference and applied statistics are advanced gems. I should imagine current texts integrate the influence of the data analyst. I wish I could suggest one book which did the trick, but I have been retired from the area for a long time. I’ll ask people I still know what they might suggest. In clinical trials there are books on design but they rarely discuss the underlying inference problem.JJ Couey is of course approaching matters from a very different perspective, which requires a type of background I don’t have. I am not familiar with the politics of the US beyond what I read.