Post B1gWLEcShwziLxpkYK by deutrino@mstdn.io
 (DIR) More posts by deutrino@mstdn.io
 (DIR) Post #B1gWLEcShwziLxpkYK by deutrino@mstdn.io
       2025-12-27T20:05:22Z
       
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       scored 200 fexofenadine tabs for $20, always buy allergy meds in the dead of winter if you cansadly, that's only a 2-month supply. I take 540mg a day during grass pollen season, or I'd be wholly incapacitated.I used to take certirizine until I re-started a certain psych med and found the combo gives me dementia-like symptoms, lost a whole summer to that! turns out cetirizine has the highest brain penetration of the "non-drowsy" #antihistamine meds, and fexofenadine the lowest.
       
 (DIR) Post #B1gWLG9T0izP6cHcdU by adam@toot.nels.onl
       2025-12-27T20:25:19Z
       
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       @deutrino Makes sense, Zyrtec/cetirizine always makes me drowsy even though it's not supposed to. But I still take it because it's the only allergy medicine that does anything for me.Strange that Allegra/fexofenadine supposedly has the least brain penetration... I only ever tried it once, and stopped when I realized it was causing bizarre surreal nightmares.
       
 (DIR) Post #B1obWs4cPdj6wH3ECe by deutrino@mstdn.io
       2025-12-31T18:01:09Z
       
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       @adam whoa, you're the first person I've heard this from. the first season I took fexofenadine it was like an all-night ticket to virtual reality, dreams so wild & vivid I woke up a couple times seriously questioning reality! and after that season, never again, even at vastly higher doses.my slightly educated wild-ass guess is maybe it affects melatonin dynamics somehow. the brain penetration info was gotten by a radio-labeled PET scan study IIRC... seems unlikely to be a mistake.