Post A74RPIe8HCh1cqE78a by TradeMinister@freespeechextremist.com
(DIR) More posts by TradeMinister@freespeechextremist.com
(DIR) Post #A6klkQ5PvDVqhg8e7k by TradeMinister@freespeechextremist.com
2021-04-29T23:07:07.631694Z
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Can mRNA-based COVID-19 vaccines cause prion disease or Alzheimer’s?Short answer: ‘no, and wassamadda, you stoopid or something?’https://sciencebasedmedicine.org/can-mrna-based-covid-19-vaccines-cause-prion-disease/
(DIR) Post #A6ktJlxRIPqGLoDAmW by Simpadoo@freespeechextremist.com
2021-04-30T00:31:57.090363Z
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@TradeMinister https://scivisionpub.com/pdfs/covid19-rna-based-vaccines-and-the-risk-of-prion-disease-1503.pdf
(DIR) Post #A6mun5bpndTXy1ZLd2 by TradeMinister@freespeechextremist.com
2021-04-30T23:57:52.647983Z
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@Simpadoo It's the same bullshit paper by a fake scientist torn to bloody shreds by someone who is actually scientifically literate in the thing I posted.But you have to understand what a prion is, and have a notion of what tRNA, mRNA, and nuclear RNA are.If you don't, you should stay in the kiddie pool. Because these are actual things that actually exist: actual science.
(DIR) Post #A6n0s3jOoClBJcrPGa by Simpadoo@freespeechextremist.com
2021-05-01T01:06:00.345726Z
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@TradeMinister interesting that people think that XXI century science is too complicated to understand. Not really seeing a proper rebuttal. I supposed Faith can keep someone on the path. I think the Rona is an obvious hoax and all the corollaries are, of course, a way to get the population to embrace things they would never have unless they have been convinced that the risk is great.Futile, as 911 and its aftermath amply demonstrated.The vaccine is not a good thing and it will be many years until the effects of the first of its kind potion is really understood.When scientific papers can’t be replicated in its majority, Faith is misplaced and the ability to argue doesn’t make something true.
(DIR) Post #A6qbZOQfuRgPmkwcnw by TradeMinister@freespeechextremist.com
2021-05-02T18:41:21.117307Z
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@Simpadoo There is no one Covid vaccine.There are two types of Covid vaccine, which are very different. Can you define these two basic families of Covid vaccine?This is a core competency for even beginning to dispense what amounts to medical advice, as is defining 'prion' and having some notion about different types of RNA to address the fake-science claim that mRNA vaccines cause prion diseases.All the orotund liberal-arts-degree verbiage that politicans and philosophers could ever produce has precisely no scientfic value and thus no relevance or worth in simple factual questions about vaccine risk/benefit analysis and giving medical advice to the general public which may have actual life/death consequences.
(DIR) Post #A72yTXnwliOjy3WrTs by ThatWouldBeTelling@poa.st
2021-05-08T17:54:32.425547Z
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@TradeMinister @Simpadoo All good, but we shouldn’t forget that a lot of people in the Third World are getting what are probably at least minimally useful inactivated whole virus vaccines from the PRC (and some from India, but it’s stopped exporting 2/3rds of its production as of mid-March). Also some “subunit” vaccines in development and at least partial deployment; paradigmatic Western example if it gets approval is Novavax: stabilized spike protein grown in bug cell culture like Sanofi/Protein Sciences FluBlock, except also has an adjuvant.(It is impressive what the anti-vaxxers keep coming up with; the latest I’ve seen is “vaccine shedding” but have they even identified what’s they’re claiming is being “shed?” That goes beyond the prion “a little knowledge is a dangerous thing” trope.)
(DIR) Post #A74RPIe8HCh1cqE78a by TradeMinister@freespeechextremist.com
2021-05-09T10:53:26.161920Z
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@ThatWouldBeTelling @Simpadoo "Vaccine shedding" LOLIt will be interesting to see if the vascular damage which the Salk Institute says the spike protein causes is also caused by current and new vaccines. A non-spike approach, such as a protein-coat target, would be helpful.
(DIR) Post #A74aWwnyGUXjn2YAPQ by ThatWouldBeTelling@poa.st
2021-05-09T12:35:39.576464Z
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@TradeMinister @Simpadoo Problem is this is an enveloped virus (https://en.wikipedia.org/wiki/Cell_membrane) so it’s not environmentally stable and has no protein coat. Your choices for immediate antibody attacks are strictly limited, there’s like two other small proteins that stick out of the surface. In terms of observed natural immunity I’ve read there’s one or more enzymes created inside cells for function, and the nucleocapsid one under the envelope, the latter considered a dangerous target to try for. Plus of course all of these can only be engaged after a cell has been hijacked, I gather more a target for cellular immunity.For spike protein pathology, I’m guessing some if not a lot or all of these mechanisms require a functioning protein, which the stabilized ones for the mRNA vaccines, Janssen and Novavax don’t supply, while (AZ/)Oxford does and Sputnik V is reputed to do. After that, I’m hoping the toxicologist’s maxim “the dose makes the poison” applies for the relatively few spike proteins which will escape vaccine hijacked cells, especially the mRNA ones that don’t create them for very long. Maybe two days someone said, maybe only hours I’m guessing.
(DIR) Post #A74nMdI9G6tRmM4qRc by TradeMinister@freespeechextremist.com
2021-05-09T14:59:27.869946Z
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@ThatWouldBeTelling @Simpadoo I think most viruses are enveloped, meaning they have an outer shell of phospholipids, glycoproteins &c. There is work on glycoproteins as vaccine targets, iirc.The vascular ACE receptor vaccine risk is theoretical and may not actually occur, but should be studied.
(DIR) Post #A7GxG8rEpUo35fYL8S by Simpadoo@freespeechextremist.com
2021-05-15T11:46:52.640042Z
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@TradeMinister Yes. Anyone that reads any news media can. Are there any other RNA vaccines out there now that have gone through the normal testing?It would be foolish to take the vaccine with a disease that has a lower mortality rate than a hang nail.Why are the shilling so hard for it? Is it because they want to show that the threat was real or is there another motive.I can tell you that the CDC data on the Rona tests is laughable. If even the litmus test used to determine spread is a joke, why would anyone take this ?
(DIR) Post #A7Gzpp3c7l720vU0tE by judgedread@freespeechextremist.com
2021-05-15T12:15:44.149643Z
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@Simpadoo They have to maintain the story because it was essential to the election steal. If it were revealed that the whole thing was spun out of almost nothing too many people would ask why.
(DIR) Post #A7HaSG35oaz354rkw4 by TradeMinister@freespeechextremist.com
2021-05-15T19:06:03.769752Z
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@Simpadoo There are some definite real-science questions about all the current Covid vaccines, and any future ones that target the spike protein.My advice, which I followed in getting the J&J vaccine, is that if you are in a low-risk group, you might want to skip them for now and wait for more data.Bullshit anti-vaxxxer fake-science like 'vaccines give you Alzheimers' only serve to discredit those raising legitimate concerns.
(DIR) Post #A7HaYxZ0wO6TmFzbo8 by TradeMinister@freespeechextremist.com
2021-05-15T19:07:16.444668Z
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@Simpadoo None of the Covid vaccines have gone thru normal testing, or they wouldn't be out for another year or so.
(DIR) Post #A7HalPpLgRsWuTZYRs by ThatWouldBeTelling@poa.st
2021-05-15T19:09:31.228245Z
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@TradeMinister What concerns do you have for the current and leading in development like Novavax spike protein vaccines?
(DIR) Post #A7HeMPEX9bb5e4gNay by ThatWouldBeTelling@poa.st
2021-05-15T19:49:49.256839Z
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@TradeMinister @Simpadoo In the US they’ve all gone through proper Phase I-III testing, the not normal thing is of course FDA Emergency Use Authorizations (EUAs) after only two months of safety data. Now with six months of efficacy data rolling Biologics License Applications have been made for the mRNA vaccines, and with the exception of @Paultron’s understanding which comes from his medical devices side of the FDA licensing experience, I keep seeing assertions that this is the final step in licensing.For example, https://www.fda.gov/vaccines-blood-biologics/development-approval-process-cber/vaccine-development-101 the first paragraph under Seeking Approval:“By submitting a BLA to the FDA, a company is seeking permission to distribute and market a vaccine for use in the United States. FDA evaluates the data to determine whether the safety and effectiveness of the vaccine has been demonstrated and whether the manufacturing and facility information assure product quality and consistency. After its evaluation, FDA decides whether to approve (also known as to license) the vaccine for use in the United States. If FDA approves the vaccine, the company is permitted to market it in the United States for use in the population for which it is approved.”(Novavax is at best having a terrible time spinning up production, which would make sense with AZ/Oxford and to a lessor extent Janssen and Sputnik V vacuuming up so much cell culture growing capacity, supplies, etc., some of which are also needed for mRNA vaccine production).For the timeline, I keep hearing periods of around six months for expedited/priority processing as a goal. Which would indeed put us around next year depending on which side of that is hit.
(DIR) Post #A7HtXmo1LqRfFfALVA by Simpadoo@freespeechextremist.com
2021-05-15T22:39:57.443106Z
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@ThatWouldBeTelling @TradeMinister lol! Bill Maher testing positive for the Rona in spite of being vaccinated kind of publicly demolished this charade.
(DIR) Post #A7HwpVmffzU7XCg7WK by ThatWouldBeTelling@poa.st
2021-05-15T23:16:46.301072Z
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@Simpadoo @TradeMinister You are so stupid you don’t realize ~95% efficacy means ~5% aren’t fully protected by a vaccine?That assumes he got a more effective mRNA vaccines instead of the one jab version of Janssen’s.
(DIR) Post #A7I79Ym3Ggvw8oaSR6 by Simpadoo@freespeechextremist.com
2021-05-16T01:12:26.960783Z
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@ThatWouldBeTelling @TradeMinisterAh, Bill Maher is part of the 5% then? How many gymnastics must you go through to convince yourself that you’ve been duped? So, another Rona shill contributing to the hoax. Nice to know that you’re intellectually dishonest. It’s a MADE IN CHINA product, obviously inferior and vomited to the people via MSM propaganda who are too stupid to understand basic math.It’s all a charade for the gullible. Unfortunately, after decades of demolishing critical thinking, it’s much easier to dupe the population than before. Lol! Keep shilling, I am immune to your lies.
(DIR) Post #A7JHz2Csn68OtTHSoC by TradeMinister@freespeechextremist.com
2021-05-16T14:48:30.818581Z
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@ThatWouldBeTelling All the spike protein vaccines may do the same (so far unproven but likely) damage that the SARS-Cov-2 spike protein does. The Salk Institute paper on vascular damage caused by spike protein overstimulation of ACE² receptor is deeply concerning.Note that this (so far unproven) damage will be caused both by vaccine spike protein and Covid infection, and that whether one has symptoms or not, eventually catching an endemic contagious virus is as likely as catching the (Corona virus) common cold: it's sort of a pick-your-poison situation.I would still prefer the adenovirus-vector vaccines over the mRNA vaccines because I suspect (with no evidence) that the mRNA vaccines are producing a heavier surge of spike protein.Note that viruses usually or always enter cells via a receptor (I believe the iron receptor is a favorite) so this kind of problem could occur with other viruses and vaccines.https://pubmed.ncbi.nlm.nih.gov/32582574/
(DIR) Post #A7JICRvyRsy8Rxlhxo by TradeMinister@freespeechextremist.com
2021-05-16T14:50:56.288537Z
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@ThatWouldBeTelling @Simpadoo I think the effectiveness of all current Covid vaccines is over 90% (except, of course, the Chinese version).
(DIR) Post #A7JIWb7W0LKojRm3rE by TradeMinister@freespeechextremist.com
2021-05-16T14:54:34.766567Z
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@Simpadoo @ThatWouldBeTelling Bear in mind that the tests are prone to false positives, and that even genuine positives seem to usually have no or mild symptoms.So the real vaccine question is not whether vaccinated people eventually test positive, but their mortality-morbidity compared to unvaccinated people.
(DIR) Post #A7JIepYmCaArpgS29g by Simpadoo@freespeechextremist.com
2021-05-16T14:56:04.040129Z
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@TradeMinister @ThatWouldBeTelling I’m more in the 60% effective camp, based on the shit accuracy of the Rona tests.
(DIR) Post #A7JIjeVaiaHr0OGDCa by Simpadoo@freespeechextremist.com
2021-05-16T14:56:56.323069Z
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@TradeMinister @ThatWouldBeTelling Yes, but the Rona is quite the unformidable bug, so I hardly think it’s worth it.
(DIR) Post #A7JKmV9u8XBWmhbRpo by mystik@midnightride.rs
2021-05-16T15:19:51.103244Z
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@TradeMinister @Simpadoo @ThatWouldBeTelling There are no "genuine positives". I'll try to explain why. Every human being is expected to test positive at least once in a while, because the targeted RNA code is present in all human beings.Yes, ill people may return "positive" more often than healthy people, but that is expected as well, because when we are ill our body gets rid of a lot of "weak" cellular stuff. Including the exosomes labeled as "coronavirus" and whatever they call "sars-cov-2" (an arbitrary selection of human RNA).Can you see how this whole "tests" thing is a tremendously large logical fallacy?There is no virus, there are only logical fallacies.
(DIR) Post #A7JMBkxYctpsz3Qyga by mystik@midnightride.rs
2021-05-16T15:35:36.112400Z
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@TradeMinister @ThatWouldBeTelling @Simpadoo Nonsense.The vaccines are literally poison and nothing more. People get more than sick after taking them.You'll understand this when you realize that there is no such thing as a "virus" (the reaction to exosomes known as "contagion" is natural and positive in nature).The real pandemic here is vitamin D deficiency.
(DIR) Post #A7JPGdaNlkRpQOc5Am by ThatWouldBeTelling@poa.st
2021-05-16T16:10:07.503358Z
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@TradeMinister Am prepared a detailed response; in the meanwhile, can you tell me on what you based your opinion that the virus vector vaccines will produce less spike protein than the mRNA ones?
(DIR) Post #A7JWPGlagAZ0wBv2Bc by ThatWouldBeTelling@poa.st
2021-05-16T17:30:07.221147Z
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@TradeMinister Sorry, I’ve been avoiding dunking on single jab Janssen because it’s what you chose and it’s not a terrible choice if you don’t need max protection, but can’t avoid it now.Not 90% for the single jab Janssen one, especially since it’s “co-primary” endpoint was preventing moderate and severe disease, and I think they didn’t get enough mild cases, the symptomatic “molecularity confirmed” (RT-PCR) to be sure that really shifted the results (all this data as of their EUA application, they know more now). This is essentially by intent, the goal being the very best single jab vaccine, two jabs eight weeks apart being tested in another Phase III trial gravy if it does better. So particularly aimed at the Third World, but also useful for situations where only one jab is desired, the homeless, those terrified of needles, etc.And thus it was tested in Brazil and especially South Africa where variants of concern are a very big or overwhelming issue, around ~71% and ~96%. Results were US > Brazil > South Africa, and as of yet we don’t think variants of concern beyond the B.1.1.7 which is mostly better at transmission are big in the US. But that might change as more people get natural or vaccine immunity, and we should assume so in our planning.Note also your body steadily fine tunes your antibody response for months after exposure to an antigen, we believe in part in anticipation of being exposed to variants (mutations) in the future.So we’re generally talking in the 70% plus or minus range and the confidence intervals are pretty wide, except getting up to 85% against “severe/critical” disease, and better and better the longer after the jab, like 28 and 56 days but limited data on the latter. 3/19 deaths vaccines/placebo, none COVID-19/effectively 7 COVID-19. Which is consistent with the above efficacy results.You can find the summarized data I’m using from the “sponsor’s” (Janssen) submission here: https://www.fda.gov/advisory-committees/advisory-committee-calendar/vaccines-and-related-biological-products-advisory-committee-february-26-2021-meeting-announcement
(DIR) Post #A7JiOF44ihlwosqEHg by ThatWouldBeTelling@poa.st
2021-05-16T19:44:23.550585Z
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@TradeMinister Not all spike proteins are alike. There’s wild type (WT) which is what is posited to be causing the pathology you’re citing, 2P stabilized (https://cen.acs.org/pharmaceuticals/vaccines/tiny-tweak-behind-COVID-19/98/i38), and what Janssen added to the 2Ps to further stabilize it. My guess is that the stabilized proteins, which are stuck in their “prefusion” configuration, that is prior to fusing with an ACE² receptor and thus can’t do that, will not cause most or any of the pathology the WT proteins might be causing.I also note of the leading Western vaccines, only the strong women of Oxford and maybe Gamaleya’s Sputnik V people ignored this line of research which started with a crude inactivated whole virus vaccine which killed several infants in the late 1960s, the researchers at the NIH finally cracking it for SARS type coronavirus vaccines. I’m under the impression out of all these vaccines AZ/Oxford has by far the worse serious adverse effect profile, although some of that is EU political posturing.There is the issue of how much spike proteins escape the hijacked cells in which they are made, I doubt it will happen, or happen much, until the cell is zapped one way or another, ultimately by the adaptive immune system responses that are the objective of vaccines.Based on theory, I believe the mRNA vaccines might produce much less of the spike protein than the viral vector ones, but that might be a desired outcome for the one jab version of Janssen, which as previously noted is their primary objective, if two jabs eight weeks apart produces better immunity that’ll be gravy.Normally it’s DNA->mRNA->proteins, then the mRNA strands are broken up into individual nucleotides and go back to the nucleus to be made into other strands. So there has to be all sorts of regulatory mechanisms that control how much protein the strands of mRNA make. A major one is the sequence of adenines (A) at its end, called poly(A) and created by https://en.wikipedia.org/wiki/Polyadenylation. Those nucleotides get removed as more and more proteins are made by a strand, and when they’re used up it’s recycled.The adenovirus vector vaccines are replication deficient versions of DNA viruses that normally cause “the common cold” in humans and something in chimpanzees for Oxford’s. They have an E1 set of genes removed so they can’t make more copies of themselves, and have the sequence for the spike protein spliced in, for Janssen and Oxford replacing that set. Both also remove the E3 set genes which subvert defenses against viruses, including the cell’s “OMG!” mechanism which causes it to press the red button of apoptosis AKA self-destruction. Which per Wikipedia “Unlike necrosis, apoptosis produces cell fragments called apoptotic bodies that phagocytic cells are able to engulf and remove before the contents of the cell can spill out onto surrounding cells and cause damage to them.”Unfortunately without a lot more study I can’t figure out how long these viral vectors will operate in cells, it might be more productive to find stated claims about that. But in theory they could do it a lot longer and and create more spike proteins, but that doesn’t say how many might be released into your bloodstream, vs. just hang out in the cells or on their surfaces.
(DIR) Post #A7LBIcPq52E9KheUDo by TradeMinister@freespeechextremist.com
2021-05-17T12:43:02.430267Z
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@mystik @Simpadoo @ThatWouldBeTelling Show up just once more with your retard-science and I'll block you.
(DIR) Post #A7LBSWc8VOtMEe7ydM by TradeMinister@freespeechextremist.com
2021-05-17T12:44:49.852982Z
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@ThatWouldBeTelling Not really on much, tbh. The techs involved, the fact that the bad mRNA reactions all seem to be with the 2nd (over?)dose.
(DIR) Post #A7LBjGCqlLQWGoHRKa by TradeMinister@freespeechextremist.com
2021-05-17T12:47:51.320833Z
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@ThatWouldBeTelling Sure, the adenovirus vaccines may be slightly less effective. They also *seem* to be less dangerous than the 2nd mRNA shot.
(DIR) Post #A7LCUYy2pJJy4EuWxM by TradeMinister@freespeechextremist.com
2021-05-17T12:56:24.252977Z
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@ThatWouldBeTelling I had read about the prefusion configuration, but haven't done detailed research on the vaccine constructions.Afaik, an actual infection should produce spike proteins as part of complete virions, not the free spike proteins I think the vaccines produce.There should be ongoing research about what if any amino acids could be substituted in the spike-coding RNA reducing affinity for the ACE² receptor while still producing an adequate immune response to the generated spike protein.
(DIR) Post #A7LGGPCAlJ51WR1Wnw by ThatWouldBeTelling@poa.st
2021-05-17T13:38:39.592830Z
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@TradeMinister “Afaik, an actual infection should produce spike proteins as part of complete virions, not the free spike proteins I think the vaccines produce.”An actual infection is going to produce both, and some scenarios of cell destruction will result in some release of the spike proteins. Part of the mRNA header of the wild type (WT) virus and copied by the vaccine varieties or at least BioNTech’s is directions of where to put the protein, in this case in the surface of the cell, in its membrane. I assume the same for the other virus surface proteins. So when viruses bud off a cell, stealing some cell membrane to make their envelope, they’ll naturally include the required surface proteins including the spike which gives them their “corona.”
(DIR) Post #A7LGeVesNtkUW5wXxo by ThatWouldBeTelling@poa.st
2021-05-17T13:43:00.860195Z
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@TradeMinister Second dose reactions of any vaccine to people naive to the antigen(s) are going to be different in nature because the immune system has already developed reactions to the antigen. The second dose, in some vaccines there’s a third dose, is really needed to gain the best efficacy. There’s a also a Pfizer illustration of a number of two dose sizes and a single big dose and what cellular (non-antibody mediated) immunity they elicit, in all cases it’s many times greater for two doses.
(DIR) Post #A7LVAzoVCaeqfNpZ7A by mystik@midnightride.rs
2021-05-17T16:25:42.742649Z
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@TradeMinister @Simpadoo @ThatWouldBeTelling
(DIR) Post #A7PSMyr74CQ3wMulfs by TradeMinister@freespeechextremist.com
2021-05-19T14:13:09.566616Z
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@ThatWouldBeTelling If you were to find the vascular ACE² spike protein question raised by the Salk Institute interesting, your research on that would be welcome. The ACE² question is the only real-science probable problem with the spike-protein vaccines I've seen. It seems likely that it may be behind some of the serious side-effects of the vaccines and pathological effects of SARS-Cov-2.
(DIR) Post #A7PV00Da8QnLMs9vOq by ThatWouldBeTelling@poa.st
2021-05-19T14:42:37.033550Z
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@TradeMinister Not sure any research by myself is required for this, because stabilized spike proteins can’t fuse with ACE2 receptors! Of course that doesn’t mean they are pathology free, so I’d first look for in vivo lab work that sees if these stabilized spike proteins can still attach themselves to ACE2 receptors, even if they then can’t then fuse with them.Here I’m mostly depending on “the dose makes the poison,” neither of the vaccines we took with their stabilized spike protein templates, super stabilized for your’s, are produced in great quantities, let alone the massive quantities in an uncontrolled infection. Also on the suspicion that (AZ/)Oxford’s worst in the West?? adverse effect profile comes from it not using a stabilized spike protein, although somehow they seem to have avoided antibody-dependent enhancement (ADE).
(DIR) Post #A7RxvdavanBl1zGmqu by TradeMinister@freespeechextremist.com
2021-05-20T19:16:12.064829Z
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@ThatWouldBeTelling I went back and read that stabilized-protein link you provide. I had read some version of that already, but it hadn't occured to me that the stabilized pre-fusion spike protein wouldn't bind with ACE². I'd like to see this confirmed with in-vitro binding affinity tests, but the theory at least is sound: an image in your link shows the huge difference in the conformation of pre- and -post spike protein. One doesn't always think about protein conformation, but if prions have taught us anything, it is that confirmation is king.
(DIR) Post #A7RzSNWQTFoch2L8Lo by ThatWouldBeTelling@poa.st
2021-05-20T19:33:19.092402Z
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@TradeMinister It’s likely to be a difference between what might be a mostly harmless binding, and the “engulfing” that the WT spike protein does after that. I’m assuming the latter is part of the pathology that appears to be associated with the spike protein, since that’s what the spike protein normally to ACE2 receptors? Are there any other posited pathological mechanisms?A simple binding at some level of affinity, since whatever starts the attachment process that followed by the engulfing should still be there, that’s could be desired to present as a target to make neutralizing antibodies against. Unless there are other human proteins that look the same to do whatever they do with ACE2 receptors, in which case that part of the protein is probably superfluous for vaccine purposes, the body won’t believe it’s alien.And here I go back to the dose make the poison, lots of ACE2 receptors in the body, only so many free spike proteins created by any first dose of a vaccine (ones from additional doses should get quickly attacked by an already activated immune system, which in the process learns how to do this better, it appears especially for cellular (non-antibody) immunity). These will mostly be the copies of the proteins that get sent to the surface of hijacked cells, vs. the ones chopped up to present epitopes of them for the immune system to recognize. Wnless there’s some mechanism which causes the insides of cells to be exposed, something apoptosis is supposed to avoid according to Wikipedia, but it makes sense. I’d want to look into all the non-apoptosis cleanup mechanisms for cells realized to be alien, or marked by antibodies as such.
(DIR) Post #A7UsEP2oyNcF6E4YNc by TheyBannedMe@freespeechextremist.com
2021-05-22T04:56:29.779983Z
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@TradeMinister the vaccines is retarded.imagine wasting an adenovirus variant that could be used to treat a disease that actually matters.