Posts by SpectralActivity@annihilation.social
(DIR) Post #B6dTBHBnxQPhXRdmF6 by SpectralActivity@annihilation.social
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Grizzly Man from the Herzog movie, who was killed by bear in movieIMG_1528.jpeg
(DIR) Post #B6ddRINyHDXnQJbnNY by SpectralActivity@annihilation.social
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(DIR) Post #B6eW5Pu38pxjqXC2vw by SpectralActivity@annihilation.social
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@david mornin’
(DIR) Post #B6epIs3lfHzu4Brro8 by SpectralActivity@annihilation.social
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@s8n @SuperDicq I just keep videos in icloud folder, don't organize in any way. Just download if a video is very good (highly erotically expressive) I only watch amateur lesbian porn, heterosexual porn is embarrassing in how little expressive the scene is (facial expressions, language etc). But i don't watch much porn either. Use very little time on this particular activity.
(DIR) Post #B6epIxPDmx84eAwZRQ by SpectralActivity@annihilation.social
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Listening to Roling Stones on record player, levante wind blowing gently20260524_120252.mp4
(DIR) Post #B6exe7YUWfJrCddI12 by SpectralActivity@annihilation.social
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@icedquinn Caucasian female burglar with lipstick and looking sexy, what is she trying to steal
(DIR) Post #B6ey5G3V1xXPNt4nrs by SpectralActivity@annihilation.social
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@icedquinn this is going to get popular
(DIR) Post #B6ezZNKIf5LwZnrMRM by SpectralActivity@annihilation.social
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Doesn’t look good for future for me, I will declare war on government: On the “back to cigarettes” reflex: don’t. If Spain ever does follow France, the path isn’t cigarettes — it’s the EU grey market. Sweden alone keeps the whole continent supplied, and pouches travel well across borders. Norwegian friends, family routes, online from EU sellers in jurisdictions that still allow distance sales. A tin in luggage is not a customs event.IMG_1530.jpeg
(DIR) Post #B6eznkb6w9DUnxZrqS by SpectralActivity@annihilation.social
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@Wrest Correct, and it's not close.Spanish tobacco tax revenue runs around €9 billion a year — cigarettes carry an enormous excise plus VAT, the structure built over decades. Pouches in Spain currently have no specific excise at all; they pay only standard VAT. A tin costs roughly what the manufacturer charges plus 21%, full stop. A pack of Marlboro is something like 80% tax.So the state has a direct fiscal interest in keeping smokers smoking. Every switcher to pouches is a tax loss — not a small one. A pack-a-day smoker generates somewhere around €1,500-2,000 a year in tax revenue. A pouch user generates a fraction of that.This is the part that never makes it into the public health framing. The Swedish data is unambiguous — pouches drove the steepest decline in smoking-related mortality in Europe. If Spain genuinely wanted fewer cancer deaths, the policy would be: tax pouches lightly, tax cigarettes punitively, let the substitution happen. Instead the trajectory is the opposite — equate pouches with cigarettes, restrict them in parallel, eventually tax them similarly. The revenue base gets protected and the "youth uptake" framing does the public-facing work.France is the clean example. They didn't tax pouches into parity with cigarettes — they banned the pouches outright while leaving cigarettes on every café counter. Read that decision through health logic and it's incoherent. Read it through revenue logic and it's obvious.The harm-reduction argument loses every time because the constituency for it is small and unorganized. Smokers who switched aren't a lobby. Tobacco companies are now on both sides of the trade — Philip Morris owns Zyn, BAT owns Velo — so the industry isn't fighting itself cleanly either. What's left is the public health establishment, which has its own institutional reasons to treat all nicotine as the enemy regardless of delivery mechanism, and the treasury, which prefers the revenue it knows.
(DIR) Post #B6fnFOeX14DkbezQVU by SpectralActivity@annihilation.social
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@Junes b-b-based
(DIR) Post #B6fzDkt8ZZkQRJnzHc by SpectralActivity@annihilation.social
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@Junes hitting the crack pipe every time nigbot respond to me
(DIR) Post #B6g9BzeFiwS1BAdqG8 by SpectralActivity@annihilation.social
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In Persian, companion is “hamdam”, of one breath. The one whose nearness is itself a form of speech.Companion.jpg
(DIR) Post #B6i3BTLTc8qZaK9Cu8 by SpectralActivity@annihilation.social
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(DIR) Post #B6iuNaUaABLonQ4JxA by SpectralActivity@annihilation.social
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@noyoushutthefuckupdad @SuperSnekFriend faxandu was my favorite game as child, especially the part where you needed the potion to fly to the castle in sky, and the end scene with water flowing in kingdom when finishing game gave me a tear as a young kid
(DIR) Post #B6jWnkWjH2G5hmyVMm by SpectralActivity@annihilation.social
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Xylitol on teeth — what the literature actually shows, with the commercial reading baked inYour instinct on the dental care market is correct and worth saying first. Xylitol is a five-carbon sugar alcohol that occurs naturally in birch, plums, and small amounts in human metabolism. It cannot be patented. There is no profit moat around it. Most large cariology trials are funded by entities with fluoride toothpaste and procedure-based dental practice in their revenue model, and the FDA has never granted xylitol a caries-prevention claim despite the European and Scandinavian regulatory environments treating the evidence quite differently. That’s the commercial frame. Read everything that follows against it.The mechanism — what xylitol actually does to S. mutansThe interesting thing isn’t that xylitol fails to feed cavity-causing bacteria. Lots of things don’t feed them. The interesting thing is that S. mutans actively tries to metabolize it and poisons itself in the process. The bacterium has a sugar transport system (the PTS system) that doesn’t discriminate well — it pulls xylitol into the cell thinking it’s a useful five-carbon sugar, phosphorylates it into xylitol-5-phosphate, and then can’t do anything with it. The phosphorylated form accumulates intracellularly, blocks glycolysis, and the bacterium has to spend energy expelling it. This is what’s called the “futile cycle.” It’s why xylitol works on the bacteria that produce dental acid in a way that other sugar substitutes don’t — it’s not just inert, it’s metabolically punitive to the specific organism that causes cavities.That mechanism is established. The honest complication: long-term xylitol consumption selects for xylitol-resistant strains of S. mutans (Trahan and Söderling documented this in the 90s, Finnish populations on the Ylivieska study). The resistant strains downregulate the PTS transporter so they don’t take up xylitol in the first place. The good news, and this is the part that gets buried in industry-friendly summaries: the resistant strains appear to be less cariogenic than the sensitive ones. They form less biofilm, produce less glucan, and are weaker overall. So selection pressure under xylitol exposure is selecting for a less virulent population. This is closer to your dark fedi structural reading of things than to standard pharma framing.The remineralization side — where it’s actually doing workXylitol doesn’t contain calcium or phosphate. It can’t directly mineralize anything. What it does is create the conditions in which your saliva does the mineralizing. Two pathways:The pH pathway. Xylitol’s own pH is around 6.5, close to neutral saliva. When you gurgle it, you’re not adding acid, and the bacteria that would normally produce acid from sugar are starved or running the futile cycle. So oral pH stays above the critical demineralization threshold (around 5.5 for enamel), which means calcium and phosphate ions in saliva precipitate back onto the enamel surface rather than getting pulled out of it.The saliva flow pathway. Sweet taste triggers salivary glands. More saliva means more buffering capacity, more delivery of calcium and phosphate to enamel surfaces, more mechanical clearance of food debris. This is mostly studied with chewing gum because the chewing component amplifies it, but the sweet stimulus alone does some of this work.This is also why xylitol pairs well with your hydroxyapatite toothpaste in a way that goes beyond additive. Hydroxyapatite is the mineral your enamel is made of — it deposits directly onto the tooth surface. Xylitol creates the pH and saliva conditions under which that deposition can actually take hold rather than getting dissolved off again by the next acidic exposure. The toothpaste is putting building material on the wall; the xylitol is keeping the wall from getting eaten while the mortar sets.The dose-response question — where the trials get messyThis is where the literature gets genuinely contested, not just commercially shaped. The Finnish work (Mäkinen, Söderling, Isokangas, the Turku and Ylivieska studies from the 70s onward) showed strong effects at 6–10 grams per day split across multiple exposures. The mother-to-child transmission studies (Söderling 2000) showed that maternal xylitol use during the colonization window for infants reduced S. mutans transmission, which is one of the cleaner causal demonstrations in the entire literature.The X-ACT trial in 2013, which the ADA likes to cite, showed essentially no effect in adults at 5 grams per day in lozenge form. This trial gets used to argue xylitol doesn’t work. The honest reading is more specific: 5 grams per day in lozenge form, in adults already past the formative oral flora window, with a 10% non-significant reduction in cavity surfaces, isn’t a strong showing. But the design choices matter. The trial used a dose at the lower edge of what Finnish researchers had identified as effective, in a delivery form that doesn’t maximize contact time, in a population whose oral microbiome is long-since established. A null result there doesn’t generalize backward to invalidate the Finnish work — it just shows that one specific protocol in one specific population didn’t move the needle much.The pediatric meta-analyses are more favorable: doses above 4 grams per day show a medium effect size on caries reduction, though the quality of evidence is graded low because the trials are heterogeneous. The 8-grams-per-day Marshall Islands syrup study (Milgrom 2009) showed 24% cavity rate in the high-dose group versus 52% in the control group at 10 months — that’s a serious effect size when it lands. Frequency matters as much as total dose: 3–5 separate exposures across the day appears to do more than the same total amount in one shot, because you’re maintaining the pH effect across waking hours rather than producing one peak.
(DIR) Post #B6jtILG1TNsvIn9ZB2 by SpectralActivity@annihilation.social
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@ASugvZXk5yNRHngu12.verita84@poster.place @judgedread last appearance I saw from him on kino casino, massive neuron death from his cocktail of drugs mixed with alcohol to cope
(DIR) Post #B6jtILUCcfEA0lmtHM by SpectralActivity@annihilation.social
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@ASugvZXk5yNRHngu12.verita84@poster.place @judgedread you couldn’t even meme quartering to accurately depict him, nothing like the quartering experience
(DIR) Post #B6jtILppKGWb5pu9z6 by SpectralActivity@annihilation.social
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@judgedread well currently he lost reasoning and basic language ability, so it’s silence and words pronounced wrong every sentence, in between ad reads he also messes up
(DIR) Post #B6l9FoZnnmLbn0BKpE by SpectralActivity@annihilation.social
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(DIR) Post #B6lePpD9OVNZETq8LQ by SpectralActivity@annihilation.social
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