(C) Daily Kos This story was originally published by Daily Kos and is unaltered. . . . . . . . . . . Diabetes: Studies of Green Tea [1] ['This Content Is Not Subject To Review Daily Kos Staff Prior To Publication.'] Date: 2024-02-07 We have been looking at all sorts of new medical devices and medications for diabetes here for months now, so it is refreshing to be able to talk about simply drinking tea as a possible preventative and treatment. I would certainly enjoy that. The Effects of Green Tea on Obesity and Type 2 Diabetes Various studies have shown the beneficial effects of green tea, not only on cardiovascular diseases but also on obesity and type 2 diabetes itself [6,7]. In a retrospective cohort study performed in Japan, a 33% risk reduction of developing type 2 diabetes was found in subjects consuming six or more cups of green tea daily compared to those consuming less than 1 cup per week [6]. Wu et al. [7] reported that Taiwanese subjects who had habitually consumed tea for more than 10 years showed lower body fat composition and smaller waist circumference. Evidences from epidemiological studies suggest the possibility of green tea being a novel strategy for treatment or prevention of obesity and diabetes. However, a limited number of clinical trials using green tea, green tea extracts (GTEs), or its main ingredient catechin have shown disappointing results in controlling hyperglycemia in type 2 diabetic patients or protecting the condition in healthy subjects. GC [gallated catechin] acutely reduces blood glucose levels mainly through its activities in the alimentary tract while increasing the glucose level when in the circulation by blocking normal glucose uptake into the tissues. They suggested the development of nonabsorbable derivatives of GC with only positive luminal effect as a prevention strategy of type 2 diabetes and obesity. As mentioned above, many researches are being performed to define the precise molecular mechanisms of green tea and ultimately, its clinical application in obesity and type 2 diabetes. It is, of course, possible that these researchers are studying the wrong chemicals. A historical example is that when orange juice was shown to cure and prevent scurvy, a following study involved boiling the juice with the intention of concentrating the active ingredient. This destroyed the Vitamin C in the juice, leading to completely negative results, setting back research for decades. The American Journal of Clinical Nutrition: Effects of green tea consumption on glycemic control: a systematic review and meta-analysis of randomized controlled trials Results Twenty-seven trials involving 2194 subjects were included in the meta-analysis. The pooled results showed that green tea significantly lowered fasting blood glucose by − 1.44 mg/dL (95%CI:-2.26, − 0.62 mg/dL; P < 0.001) with no obvious heterogeneity (I2 = 7.7%). However, green tea consumption did not significantly affect fasting insulin and HbA1c values. The mean differences were − 0.46μIU/mL (95% CI: − 1.10, 0.17μIU/mL; P = 0.21) for fasting insulin and − 0.06%; (95% CI: − 0.12, 0.01%; P = 0.07) for HbA 1c concentrations. Heterogeneity was significant in fasting insulin (I2 = 46.8%) and mild in HbA 1c (I2 = 1.7%). Conclusions In short-term trials, green tea supplementation significantly reduced fasting glucose, but had no significant effect on fasting insulin and HbA 1c . Long-term trials assessing the effects of green tea supplementation on glycemic control are needed. Green tea and type 2 diabetes Green tea catechins are involved in many biological activities such as antioxidation and modulation of various cellular lipid and proteins. Thus, they are beneficial against degenerative diseases, including obesity, cancer, cardiovascular diseases, and various inflammatory diseases. Some reports also suggest that daily consumption of tea catechins may help in controlling type 2 diabetes. However, other studies have reported that chronic consumption of green tea may result in hepatic failure, neuronal damage, and exacerbation of diabetes, suggesting that interindividual variations in the green tea effect are large. This review will focus on the effect of green tea catechins extracted from the Camellia sinensis plant on type 2 diabetes and obesity, and the possible mechanistic explanation for the experimental results mainly from our laboratory. It is hoped that green tea can be consumed in a suitable manner as a supplement to prevent the development of type 2 diabetes and obesity. x This is the flower of tea plant (Camellia sinensis) Rize #Türkiye pic.twitter.com/mvZxFkTl84 — Awais Khan (@awaicekhan) February 4, 2024 Effects of Green Tea Extract on Insulin Resistance and Glucagon-Like Peptide 1 in Patients with Type 2 Diabetes and Lipid Abnormalities: A Randomized, Double-Blinded, and Placebo-Controlled Trial Within-group comparisons showed that green tea extract caused a significant decrease in triglyceride and homeostasis model assessment of insulin resistance index after 16 weeks. Green tea extract also increased significantly high density lipoprotein cholesterol. Notes From Myself I have had better blood glucose control of late, and have had to go off Ozempic as a result. As long as I avoid carbs, I don’t need to take insulin, either. I don’t pretend to understand it. My doctor is checking me for anything untoward that might cause that. I have done most of my experiments on sugary and other high-carb foods that some allege are harmless for diabetics. Nope. They all raise my blood glucose sharply, except for steel-cut oats, which do it only slowly, and with a lower peak. [END] --- [1] Url: https://www.dailykos.com/stories/2024/2/7/2221852/-Diabetes-Studies-of-Green-Tea?pm_campaign=front_page&pm_source=latest_community&pm_medium=web Published and (C) by Daily Kos Content appears here under this condition or license: Site content may be used for any purpose without permission unless otherwise specified. via Magical.Fish Gopher News Feeds: gopher://magical.fish/1/feeds/news/dailykos/