[HN Gopher] Bacteria found in the human intestine capable of imp...
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Bacteria found in the human intestine capable of improving muscle
strength
Author : gnabgib
Score : 108 points
Date : 2026-04-05 19:01 UTC (3 hours ago)
(HTM) web link (www.ugr.es)
(TXT) w3m dump (www.ugr.es)
| rendall wrote:
| ...in mice. :/
| Aboutplants wrote:
| Maybe we need to flip it and start testing new mouse drugs on
| Humans?
| RobRivera wrote:
| We need deeper research into mouse bites as medicine.
| wpm wrote:
| More mouse bites!
| wellthisisgreat wrote:
| The mouse lobby rears its [tiny] head again
| stefs wrote:
| As always. But it's a first step.
| jb1991 wrote:
| The reflex "in mice" meme has been annoying for quite some
| time.
| adrian_b wrote:
| It is not that simple.
|
| They have found first a correlation between the presence of
| this species of bacteria and muscle strength in humans.
|
| Then they have made an attempt to determine whether this
| correlation reflects a causal relationship.
|
| So they have fed mice previously treated with antibiotics, to
| remove their own gut bacteria, with this kind of bacteria
| extracted from humans.
|
| They have indeed seen an increase in muscular strength at the
| mice that have received the human bacteria, which seems to
| confirm causality between the presence of this bacterium and
| muscle strength.
|
| While they have also determined the biochemical changes in
| muscles that have caused increased strength, the mechanism of
| how the bacteria have influenced that remains a mystery.
| Perhaps this bacterium produces some substance that mimics a
| human hormone, e.g. a steroid.
|
| Paywalled research article:
| https://gut.bmj.com/content/early/2026/03/03/gutjnl-2025-336...
| rendall wrote:
| So, literally, "Bacteria found in the human intestine capable
| of improving muscle strength in mice" then.
| SV_BubbleTime wrote:
| If we wanted to we could either make super mice. Or have a
| great head start on really unethical but impressive human
| health progress... that just comes from all the horrible
| human testing that would be necessary.
| grg0 wrote:
| This is why I tell my gym bros that they should quit all that
| Celsius garbage and stick to the basics. You should measure your
| gut health by the quality of your feces (consistency, texture,
| colour, shape), and then your muscles and rest of your body will
| thank you. This research is evidence of that. The science is
| still catching up.
| stefs wrote:
| Celsius?
| grg0 wrote:
| Corrected, thank you.
| acessoproibido wrote:
| What do you mean by celcius garbage?
|
| Fun fact: in Germany most toilets have a built in 'inspection
| plate' so you can look at your shit before you flush it. In
| other places I often found it hard to judge the quality because
| you can't even see it well or it gets flushed instantly
| grg0 wrote:
| I meant Celsius, a popular energy drink in the US, but more
| generally that and the processed foods people take in for
| some supposed performance gains.
| SV_BubbleTime wrote:
| It's gross sugar water. I accidentally bought some once and
| years later I found out people are intentionally drinking
| it.
| unsupp0rted wrote:
| I always wondered if the "inspection plate" was really for
| inspection or some side-effect of plumbing or something
| p1anecrazy wrote:
| One explanation I heard is "helps save water when flushing"
| b65e8bee43c2ed0 wrote:
| I assume they existed to prevent backsplash.
| soopypoos wrote:
| it also helps avoid Neptune's kiss
| b112 wrote:
| It's literally in the bowl you were just sitting in. I'm not
| sure where the inspection plate goes. Is this an AI saying
| this? Is the rest of the thread AIs? Is this all made up.
| What's happening!?
|
| I thought learning about bidets was a new experience, now
| inspection plates?!
|
| I thought I understood this part of my life.
|
| _scared and confused_
| kadoban wrote:
| It's just different shapes of toilets. There's a part
| without water directly under you, and then when you flush
| it's flooded.
| rokkamokka wrote:
| Just do a quick search for German toilet and you'll see.
| grg0 wrote:
| There are no AIs here, only gains.
| tvshtr wrote:
| "Bro, take a look at my poop"
| notesinthefield wrote:
| It is so wonderful to hear someone else say this. My spouse and
| friends think In so weird for emphasizing optimizing your diet
| for things that digest well, macro dense and give you good
| shits. I am quietly pleased when my own looks completely normal
| and uninteresting.
| RobRivera wrote:
| GAINS
| youalmosthadit wrote:
| No grain no gain
| toomuchtodo wrote:
| Roseburia inulinivorans probiotic when? Probably add it to the
| premade protein shakes and mix specific to those building muscle.
|
| https://en.wikipedia.org/wiki/Roseburia_inulinivorans
| Giorgi wrote:
| Well... assuming this article is just shilling, soon.
| FurstFly wrote:
| My gym bros gonna be so shocked lol
| shevy-java wrote:
| So Homer Simpson was right in the end.
|
| Beer is basically fermented sugar (well, glucose converted to
| ethanol by yeast, for the most part; though its maltose first,
| yeast, bacteria etc... prefer glucose and maltose is a
| disaccharide of glucose: Maltose).
| mikrl wrote:
| Pretty sure Duff was a heavily filtered macro beer.
|
| Not saying engineered beer is necessarily bad- Sapporo and
| Asahi never disappoint- but I imagine you would want to stick
| to unfiltered and unpasteurized to retain some of the more...
| alive compounds.
| joshuahaglund wrote:
| No beer has nothing to do with Roseburia genus bacteria
| rramadass wrote:
| Perhaps there is also a direct correlation between this
| microbiome and longevity in the so-called "blue zones" of the
| world like Okinawa, Sardinia etc.
|
| We _are_ what we eat.
| tvshtr wrote:
| Some of the blue zones were disproven, due to falsified
| documentation or lack of it.
| patmorgan23 wrote:
| IIRC there are several of the "Blue Zones" where just bad
| government records. (People who had incorrect birth dates, or
| had already died and the government just didn't know about it)
| SV_BubbleTime wrote:
| Jose DeSanquin Demarco of Bolivia is now the world's oldest
| man at 117, he attributes his health to 10 hours daily in the
| sun and fields farming quinoa.
|
| Photographed here, Jose's 90 year old wife holds their
| newborn twins.
| jareklupinski wrote:
| > We are what we eat.
|
| putting together a theory on how bacteria organized
| multicellular life to exploit our macro-movements and
| proliferate between damp spots
| roschdal wrote:
| I need this
| culi wrote:
| It works by converting fibers into butyrate. You should maintain
| a high fiber diet to promote Roseburia in your gut
| adrian_b wrote:
| It is known that the bacteria that produce high amount of
| butyrate are beneficial, e.g. by decreasing the risk of colon
| cancer, but this does not seem sufficient to explain the
| increase in muscle strength that seems to be caused by this
| species alone.
|
| The study has first found in humans a correlation between
| muscle strength and the presence of this bacterium. Then they
| have attempted to determine whether this correlation is due to
| a causal relationship by killing the gut bacteria in mice, then
| feeding them with this kind of human gut bacteria. The result
| was an increased muscle strength, which seems to confirm
| causality.
|
| How the bacteria increase muscle strength remains unknown. I
| think that a possible explanation may be that this bacterium
| produces some substance that mimics a human hormone, e.g. a
| steroid, in which case it would be a kind of natural doping.
| sandworm101 wrote:
| Natural or otherwise, one must wonder if there are similar
| downsides.
| adrian_b wrote:
| True.
| DiscourseFan wrote:
| I've always eaten a ton of fiber, to the point where if I stop
| I get constipated, and I've always put on muscle fairly easily.
| b65e8bee43c2ed0 wrote:
| the fiber will promote all bacteria in your gut, not just this
| particular strain.
| blargey wrote:
| All fiber-consuming gut bacteria, yes - but that's basically
| synonymous with "good"/beneficial gut bacteria, so it's good
| advice even if it doesn't give people the massive gainz they
| might have been hoping for.
| moffkalast wrote:
| You know it would be funny if at least once the finding would
| be "you should eat more hamburgers" or something.
| ben8bit wrote:
| Eat some apples and add 10lb to your bench. Nice!
| sublinear wrote:
| > This opens up the possibility that the bacterium under
| investigation could be used as a probiotic to help preserve
| muscle strength during aging
|
| Maybe, but it's really hard to control for other variables here.
| They don't know what's causing this bacteria to diminish over
| time in older adults in the first place.
|
| It could totally just be dietary habits getting worse over time
| as people let themselves go. Regardless of age, most people
| already don't eat enough protein and when they do they might not
| be getting "complete" proteins either (missing amino acids is
| common with plant-based foods).
| fylo wrote:
| For me personally, as I've gotten older I have continued to eat
| better and more consistently than I ever did earlier in life. I
| think the long term study of your own life tends to show you
| that diet is one of, if not the, primary factor in short and
| long term health and well being.
| ramoz wrote:
| Did quick research on how to support the bacteria growth
|
| > Dietary modifications that emphasize high-fiber and prebiotic
| foods and dietary supplements may support the healthy growth of
| Roseburia [1]
|
| > As stated above, a Mediterranean diet is associated with
| increased Roseburia growth. This diet emphasizes primarily plant-
| based foods: whole fruits and vegetables, whole grains, legumes,
| nuts and seeds, olive oil, and fatty fish. The high fiber and
| resistant starch content of these foods may fuel Roseburia and
| the other beneficial flora of the human microbiome [1]
|
| > Polyphenols are plant compounds abundant in fruits, vegetables,
| tea, and coffee. Emerging research indicates that polyphenols can
| enhance Roseburia abundance indirectly by inhibiting harmful
| bacteria and fostering beneficial ones. [2]
|
| [1] https://www.rupahealth.com/post/roseburia-spp-101
|
| [2] https://www.innerbuddies.com/pages/gut-microbiome-101/gut-
| ba...
| OfirMarom wrote:
| Thanks for the dietary info! Helps make it concrete.
| underlipton wrote:
| tl;dr They don't know.
|
| I wish scientists would be more open about how little they
| understand digestion and nutrition, particularly on an
| individual level. Advice gets presented as an if-then, when
| it's not.
| soopypoos wrote:
| Neisseria gonorrhoeae doesn't even have muscles but it can pull
| 100,000x its own weight
| emanuele-em wrote:
| Every few months there's a new study showing gut bacteria control
| yet another thing we thought was "us." Mood, cognition, immune
| response, and now muscle strength. Starting to wonder what's even
| left.
| dd8601fn wrote:
| And yet, still no serious fixes for any of it that aren't just
| jabronis pitching overpriced and ineffective supplements.
| g-b-r wrote:
| Will people really go after Tom Brady's stuff now? xD
| sharpshadow wrote:
| Active cultures are available[0] and there is certainly a way to
| make them available to the gut isn't there?
|
| 0. https://webshop.dsmz.de/en/bacteria/Roseburia-
| inulinivorans....
| blitzar wrote:
| Gym bros are going to be eating their own faeces for the gainz.
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(page generated 2026-04-05 23:01 UTC)