[HN Gopher] Entities enabling scientific fraud at scale (2025)
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       Entities enabling scientific fraud at scale (2025)
        
       Author : peyton
       Score  : 244 points
       Date   : 2026-03-11 13:32 UTC (9 hours ago)
        
 (HTM) web link (doi.org)
 (TXT) w3m dump (doi.org)
        
       | pixl97 wrote:
       | This is Goodhart's law at scale. Number of released papers/number
       | of citations is a target. Correctness of those papers/citations
       | is much more difficult so is not being used as a measure.
       | 
       | With that said, due to the apparent sizes of the fraud networks
       | I'm not sure this will be easy to address. Having some kind of
       | kill flag for individuals found to have committed fraud will be
       | needed, but with nation state backing and the size of the groups
       | this may quickly turn into a tit for tat where fraud accusations
       | may not end up being an accurate signal.
       | 
       | May you live in interesting times.
        
         | armchairhacker wrote:
         | There's an accurate way to confirm fraud: look for
         | inconsistencies and replicate experiments.
         | 
         | If the fraudsters "fail to replicate" legitimate experiments,
         | ask them for details/proof, and replicate the experiment
         | yourself while providing more details/proof. Either they're
         | running a different experiment, their details have
         | inconsistencies, or they have unreasonable omissions.
        
           | wswope wrote:
           | Yeah, but this happens all the time.
           | 
           | >>95% of the time, the fraudsters get off scot-free. Look at
           | Dan Ariely: Caught red-handed faking data in Excel using the
           | stupidest approach imaginable, and outed as a sex pest in the
           | Epstein files. Duke is still giving him their full backing.
           | 
           | It's easy to find fraud, but what's the point if our
           | institutions have rotten all the way through and don't care,
           | even when there's a smoking gun?
        
           | pixl97 wrote:
           | Of course this is slightly messy too. Fraudsters are probably
           | always incorrect, of course they could have stolen the data.
           | But being incorrect doesn't mean your intentionally
           | committing fraud.
        
           | john_strinlai wrote:
           | that approach is accurate, but not scalable.
           | 
           | the effort to publish a fraudulent study is less (sometimes
           | much less) than the effort to replicate a study.
        
           | awesome_dude wrote:
           | Is it that easy?
           | 
           | Machine Learning papers, for example, used to have a terrible
           | reputation for being inconsistent and impossible to
           | replicate.
           | 
           | That didn't make them (all) fraudulent, because that requires
           | intent to deceive.
        
             | itintheory wrote:
             | What do you think it is about machine learning that makes
             | it hard to replicate? I'm an outsider to academic research,
             | but it seems like computer based science would be uniquely
             | easy - publish the code, publish the data, and let other
             | people run it. Unless it's a matter of scale, or access to
             | specific hardware.
        
               | renewiltord wrote:
               | A lot of things are easy if you ignore the incentive
               | structure. E.g. a lot of papers will no longer be
               | published if the data must be published. You'd lose all
               | published research from ML labs. Many people like you
               | would say "that's perfectly okay; we don't need them" but
               | others prefer to be able to see papers like Language
               | Models Are Few-Shot Learners
               | https://arxiv.org/abs/2005.14165
               | 
               | So the answer is that we still want to see a lot of the
               | papers we currently see because knowing the technique
               | helps a lot. So it's fine to lose replicability here for
               | us. I'd rather have that paper than replicability through
               | dataset openness.
        
               | armchairhacker wrote:
               | But the lab must publish at least the general category of
               | data, and if that doesn't replicate, then the model only
               | works on a more specific category than they claim (e.g.
               | only their dataset).
        
               | awesome_dude wrote:
               | Even with the exact same dataset and architecture, ML
               | results aren't perfectly replicable due to random weight
               | initialisation, training data order, and non-
               | deterministic GPU operations. I've trained identical
               | networks on identical data and gotten different final
               | weights and performance metrics.
               | 
               | This doesn't mean the model only works on that specific
               | dataset - it means ML training is inherently stochastic.
               | The question isn't 'can you get identical results' but
               | 'can you get comparable performance on similar data
               | distributions.
        
               | armchairhacker wrote:
               | Then researchers should re-train their models a couple
               | times, and if they can't get consistent results, figure
               | out why. This doesn't even mean they must throw out the
               | work: a paper "here's why our replications failed"
               | followed by "here's how to eliminate the failure" or
               | "here's why our study is wrong" is useful for future
               | experiments and deserves publication.
        
               | awesome_dude wrote:
               | As per my previous comment - we are discussing stochastic
               | systems.
               | 
               | By definition, they involve variance that cannot be
               | explained or eliminated through simple repetition.
               | Demanding a 'deterministic' explanation for stochastic
               | noise is a category error; it's like asking a
               | meteorologist to explain why a specific raindrop fell an
               | inch to the left during a storm replication.
        
           | ertgbnm wrote:
           | That would be great if journals bothered publishing
           | replication studies. But since they don't, researchers can't
           | get adequate funding to perform them, and since they can't
           | perform them, they don't exist.
           | 
           | We can't look for failed replication experiments if none
           | exist.
        
         | bwfan123 wrote:
         | > This is Goodhart's law at scale.
         | 
         | Also, Brandolini's law. And Adam Smith's law of supply and
         | demand. When the ability to produce overwhelms the ability to
         | review or refute, it cheapens the product.
        
         | otherme123 wrote:
         | > Number of released papers/number of citations is a target
         | 
         | There was this guy, well connected in the science world, that
         | managed to publish a poor study quite high (PNAS level). It was
         | not fraud, just bad science. There were dozens of papers and
         | letters refuting his claims, highlighting mistakes, and so...
         | Guess what? Attending to metrics (citations, don't matter if
         | they are citing you to say you were wrong and should retract
         | the paper!), the original paper was even more stellar on the
         | eyes of grants and the journal itself.
         | 
         | It was rage bait before Facebook even existed.
        
         | bonoboTP wrote:
         | > Number of released papers/number of citations is a target
         | 
         | Only in stupid university leaderships is that truly what gets
         | you hired or promoted. It's simply not true. Junior researchers
         | in fact are believing it stronger than the facts actually
         | support. Yes, you have to have a solid amount of publications,
         | but doing a ridiculous amount of low-impact salami-sliced stuff
         | or getting your name on a ton of papers where you did no real
         | work is not going to win you a job. People who evaluate
         | applications also live in this world and know that these
         | metrics are being gamed. It's a cat and mouse game but the cats
         | are also paying attention. You can only play this against
         | really dumb government bureaucracies that mechanically give
         | points for publications and have hard numerical criteria etc.
         | Good institutions don't do that.
         | 
         | Good evaluators actually read the papers themselves. Of course
         | you can't read the papers of every single applicant if there
         | are many. But once the applicant gets into the a somewhat
         | filtered down list, reading the paper(s) or having an interview
         | about it, or having them give a talk is much more informative
         | than the number of the papers. Still not perfect, because some
         | people can't communicate well, but communicating is part of the
         | job, so maybe that's super bad but somewhat bad.
         | 
         | Evaluators will use also other evidence such as recommendation
         | letters (informally being aware of the reputation of the
         | recommender), previous fellowships or grants obtained, etc.
         | 
         | None of these are foolproof in themselves. But someone who has
         | super few publications relative to their career stage will need
         | some other piece of evidence in favor.
         | 
         | In machine learning and AI, peer reviews are known to be quite
         | random. If you have a good Arxiv-only paper that makes sense
         | and you can give a good talk on it and answer questions, that
         | will get you further than having a rubberstamp on some paper
         | that's "meh, so what".
         | 
         | There are some players in this game (which includes funding
         | agencies, journals, university administration, hiring
         | committees, conference organizers, students, etc) that are more
         | ossified and slow-moving than others.
         | 
         | And it's also true that double blind peer review and the
         | rubberstamp of a top-tier conference was mostly beneficial to
         | small, not well connected research groups, as it puts the paper
         | on an equal footing with the big labs. The more this system
         | erodes, to more we fall back to reputation and branding of big
         | labs and famous researchers. Again, because there is no
         | infinite time and infinite wisdom available to pick from
         | applicants and there never will be. There are only tradeoffs.
        
       | gjsman-1000 wrote:
       | The future of science, the Internet, and all things: The Library
       | of Babel by Jorge Luis Borges.
       | 
       | Some things should not have been democratized. Silicon Valley
       | assumes that removing restrictions on information brings freedom,
       | but reality shows that was naive.
        
         | honeycrispy wrote:
         | You shouldn't just assume that the inverse would be free from
         | fraud. The incentives for fraud still apply even when the
         | system is not democratized.
        
           | gjsman-1000 wrote:
           | Except with AI, a fraudulent gatekept world would still be a
           | smaller percentage of fraud than what is coming. Infinite
           | scale fraud.
           | 
           | The soviets may have rigged a few studies; but the
           | democratized world now faces almost all studies being rigged.
        
             | honeycrispy wrote:
             | I think it'd be a different form of fraud that would be
             | much harder to discredit. Think sugar industry blaming fat
             | for health issues. More of that.
        
         | rdevilla wrote:
         | Tearing down gatekeeping (i.e. "high standards") in pursuit of
         | maximal inclusivity is just another way of saying "regression
         | to the mean."
         | 
         | The gate has been removed from the signal chain, and now the
         | noise floor is at infinity.
        
           | qsera wrote:
           | There is a saying in my native language that goes something
           | like "If you mix poison and milk, the milk will turn
           | poisonous, instead of poison becoming milk (aka beneficial)".
           | 
           | I guess, to convert it into this context, we can say that if
           | you mix the high minded and infantile (which I think is what
           | Internet and social media did), the high minded becomes
           | infantile, instead of the other way around.
        
           | convolvatron wrote:
           | there is no 'sin of maximal inclusivity here', the gate is
           | broken, but primarily because it was largely an honor system
           | before, and no one has the motivation or resources to really
           | dig into a lot of these papers.
           | 
           | in no sense was it corrupted by the desire to include a
           | larger population in journal publications.
        
         | leoc wrote:
         | In what way was it was democratised? We're not talking about
         | Substacks and YouTube channels here, we're not even talking
         | about arXiv preprints and the like, we're talking about peer-
         | reviewed journal publications, and that system remains gated in
         | much the same way that it was in the 1980s when it comes to
         | trying to publish in it. If anything this system is the poster
         | child for top-down gatekeeping by the recognised authorities,
         | and it's precisely the value of that official recognition that
         | makes people so desperate to break into it. The major changes
         | seem to have been the easy availability of author publication
         | lists and the advent of publication metrics, not things which
         | have been or were ever meant to be particularly democratising
         | for would-be authors; and an increase in the number of people
         | playing the game, driven to a large extent by increasing
         | participation from developing countries, and hopefully not many
         | people would have the gall to argue for a ban on developing-
         | country participation.
        
         | niam wrote:
         | The Library of Babel comparison is too fatalistic imo, even
         | granting that it's maybe just an extreme example. The real
         | world doesn't quite resemble a closed system with no metadata.
         | We can still establish chains of trust.
         | 
         | Whether or not people will build resilient chains is another
         | story, contingent on whether the strength of that chain
         | actually matters to people. It probably doesn't for a lot of
         | people. Boo. But inasmuch as _I_ care, I feel I ought to be
         | free to try and derive a strong signal through the noise.
        
       | RobotToaster wrote:
       | It kinda skips over how large mainstream journals, with their
       | restrictive and often arbitrary standards, have contributed to
       | this. Most will refuse to publish replications, negative studies,
       | or anything they deem unimportant, even if the study was
       | conducted correctly.
        
         | tppiotrowski wrote:
         | Maybe we need a journal completely dedicated to replication
         | studies? It would attract a lot of attention I think.
        
           | pfdietz wrote:
           | And _funding_ dedicated to replication studies.
        
             | fsckboy wrote:
             | paid by the original authors if their study fails to
             | replicate
        
           | MichaelDickens wrote:
           | Economics has the Journal of Comments and Replications in
           | Economics: https://jcr-econ.org/
        
           | LargeWu wrote:
           | Is there a viable career path for researchers who choose to
           | focus on replication instead of novel discoveries? I assume
           | replications are perceived as less prestigious, but it's also
           | important work.
        
             | stanford_labrat wrote:
             | sadly no, this is not a thing and it's critically needed.
             | 
             | top on my list of things to do if i were a billionaire:
             | launch an institute for the sole purpose of reproducing
             | other's findings.
        
             | cvwright wrote:
             | The closest thing we have is, in security / privacy /
             | cryptography, you can write "attack" papers.
             | 
             | It's not perfect. You don't get any credit unless you can
             | demonstrate a substantial break of the prior work. But it's
             | better than in a lot of other fields.
        
           | fc417fc802 wrote:
           | We already have archival journals. What's missing is funding
           | and any prospect of career advancement.
        
         | CGMthrowaway wrote:
         | So much of this started with the rise of the peer-review
         | journal cartel, beginning with Pergamon Press in 1951
         | (coincidentally founded by Ghislaine Maxwell's father). "Peer
         | review" didn't exist before then, science papers and discussion
         | was published openly, and scientists focused on quality not
         | quantity.
        
           | john_strinlai wrote:
           | > _Pergamon Press in 1951 (coincidentally founded by
           | Ghislaine Maxwell 's father)_
           | 
           | perhaps a bit off-topic, but what is coincidental about this
           | and/or what is the relevance of Ghislaine Maxwell here?
        
             | benterix wrote:
             | It's useless, but I'm ashamed to admit I found this tiny
             | piece of trivia interesting.
        
               | readthenotes1 wrote:
               | Like the paywall blocking many scientific arti6, perhaps
               | it would be best if we released also the Epstein Files?
        
             | anonymars wrote:
             | I imagine it's the interesting peculiarity that the same
             | people seem to crop up over and over and over again. Six
             | degrees of Kevin Bacon or something, except it's like one
             | or two degrees. As George Carlin said, "it's a big club,
             | and you ain't in it"
             | 
             | For example Donald Barr (father of twice-former US Attorney
             | General Bill Barr) hiring college-dropout Jeffrey Epstein
             | whilst headmaster at the elite Dalton School
             | 
             | Additional fun facts about Donald Barr: he served in US
             | intelligence during WWII, and wrote a sci-fi book featuring
             | child sex slaves
        
               | jl6 wrote:
               | Also the Epstein-Barr virus causes Mono, the clone of
               | .NET, which was created by Bill Gates, known associate of
               | Epstein, whose father was president of the Washington
               | State Bar Association. And you know who _else_ works in
               | Washington? Join the dots, people.
        
               | Henchman21 wrote:
               | This might be my fav HN comment ever. Well done!
        
               | underlipton wrote:
               | We call people who make connections like these
               | "conspiracy theorists," until they're right, at which
               | point we call them "right". And somewhere in between, if
               | they manage to get a job, we call them "Simpsons
               | writers."
        
             | tialaramex wrote:
             | Ghislaine's father (Robert Maxwell) was _also_ a terrible
             | person but for different reasons.
             | 
             | Robert Maxwell was a crook, he used pension funds (supposed
             | to be ring-fenced for the benefit of the pensioners) to
             | prop up his companies, so, after his slightly mysterious
             | death it was discovered that basically there's no money to
             | pay people who've been assured of a pension when they
             | retire.
             | 
             | He was also very litigious. If you said he was a crook
             | _when he was alive_ you 'd better hope you can prove it
             | _and_ that you have funding to stay in the fight until you
             | do. So this means the sort of people who call out crooks
             | were _especially_ unhappy about Robert Maxwell because he
             | was a crook _and_ he might sue you if you pointed it out.
        
             | bryanrasmussen wrote:
             | I believe by saying it is coincidental they are saying
             | there is probably no relevance, just an interesting piece
             | of trivia, why put out this interesting piece of trivia?
             | Because maybe someone will be able to make an argument of
             | relevance.
        
               | pocksuppet wrote:
               | It's more than coincidental, but tangential to the point.
               | It shows crime runs in families.
        
             | bartread wrote:
             | If you want to know more about the history of Pergamon
             | Press there's a great Behind the Bastards episode on Robert
             | Maxwell (Ghislaine Maxwell's father) - who himself was a
             | scumbag in a variety of ways that were entirely distinct
             | from Ghislaine Maxwell's brand of scumbaggery - that covers
             | this. Might even be a multipart episode - it's a while
             | since I've listened to it, but I have a feeling it's at
             | least a two parter.
        
             | pessimizer wrote:
             | "Coincidental" means random, with no causal connection
             | being explicitly claimed. It just means that two things
             | share some characteristic (such as being relatives.) The
             | thing that is coincidental is that the person who founded
             | the company being discussed is also the father of another
             | person who current events have brought into prominence.
             | 
             | It's why you would say something like "more than
             | coincidental" if you were trying to make some causal claim,
             | like one thing causing the other, or both things coming
             | from the same cause.
             | 
             | So, "What is coincidental about that?" is a weird question.
             | It reads as a rhetorical claim of a causal connection
             | through asking for a denial or a disproof of one.
        
               | john_strinlai wrote:
               | sorry.
               | 
               | what is the relevance to the discussion about journals
               | and peer review is my main question.
               | 
               | if i randomly mentioned that your name appears to be an
               | alternate spelling of a 3-band active EQ guitar pedal,
               | coincidentally sharing all of the letters except one, in
               | my reply to you, most people would be confused. that is
               | how i felt when randomly reading "Ghislaine Maxwell" in
               | this context of journals and peer review.
        
           | leoc wrote:
           | I'm not sure that the system was ever that near to
           | perfection: for example, John Maddox of _Nature_ didn 't like
           | the advent of pre-publication peer review, but that
           | presumably had something to do with it limiting his
           | discretion to approve and desk-reject whatever he wanted. But
           | in any case it (like other aspects of the cozy interwar and
           | then wartime scientific world) could surely never have
           | survived the huge scaling-up that had already begun in the
           | post-war era and created the pressure to switch to pre-
           | publication peer reivew in the first place.
        
           | throwaway27448 wrote:
           | > coincidentally founded by Ghislaine Maxwell's father
           | 
           | A crazy world we live in where Robert Maxwell's daughter is
           | more notorious than he is.
        
             | LarsDu88 wrote:
             | Fun fact, he almost got the worldwide console rights to
             | Tetris back in the 80s, and tried going to Soviet officials
             | to get those rights. To the point he's the antagonist of a
             | recent "Tetris" movie that came out.
        
               | throwaway27448 wrote:
               | This is a fun fact, thank you.
        
             | lovich wrote:
             | Never knew of the guy but what a terrible sounding person
             | from his Wikipedia at least.
             | 
             | Shit apple doesn't fall far from the shit tree I guess.
        
           | butILoveLife wrote:
           | >scientists focused on quality not quantity.
           | 
           | I know a PhD professor doing post doc or something, and he
           | accepted a scientific study just because it was published in
           | Nature.
           | 
           | He didn't look at methodology or data.
           | 
           | From that point forward, I have never really respected
           | Academia. They seem like bottom floor scientists who never
           | truly understood the scientific method.
           | 
           | It helped that a year later Ivys had their cheating scandals,
           | fake data, and academia wide replication crisis.
        
             | fc417fc802 wrote:
             | When I read something in a textbook I blindly believe it,
             | depending on the broader context and the textbook in
             | question. Is that a bad thing?
             | 
             | People are constantly filtering everything based on
             | heuristics. The important thing is to know how deep to look
             | in any given situation. Hopefully the person you're
             | referring to is proficient at that.
             | 
             | Keep in mind that research scientists need to keep abreast
             | of far more developments than any human could possibly
             | study in detail. Also that 50% of people are below average
             | at their job.
        
               | irishcoffee wrote:
               | > When I read something in a textbook I blindly believe
               | it, depending on the broader context and the textbook in
               | question. Is that a bad thing?
               | 
               | It is if what you read is factually incorrect, yes.
               | 
               | For example, I have read in a textbook that the tongue
               | has very specific regions for taste. This is patently
               | false.
               | 
               | > Keep in mind that research scientists need to keep
               | abreast of far more developments than any human could
               | possibly study in detail. Also that 50% of people are
               | below average at their job.
               | 
               | So, we should probably just discount half of what we read
               | from research scientists as "bad at their job" and not
               | pay much attention to it? Which half? Why are you
               | defending corruption?
        
               | cyberax wrote:
               | The problem is that you can't just verify everything
               | yourself. You likely have your own deadlines, and/or you
               | want to do something more interesting than replicating
               | statistical tests from a random paper.
        
               | irishcoffee wrote:
               | > The problem is that you can't just verify everything
               | yourself.
               | 
               | So the problem is reduced to "I believe what I want! This
               | person said it and so I think it's true!"
               | 
               | Sounds like politics in a nutshell.
        
               | cyberax wrote:
               | No, it's not. It's reduced to "I trust people from a
               | respectable scientific journal with 150 years of
               | history".
               | 
               | > Sounds like politics in a nutshell.
               | 
               | Again, no. It sounds like the division of labor. The
               | thing that made modern human societies possible.
        
               | irishcoffee wrote:
               | Division of labor. Dividing labor between the "i'll pay
               | you to work" and "I'm paid to work"
               | 
               | The jokes write themselves,
        
               | cyberax wrote:
               | Yes? What is exactly funny here? This is literally how
               | the civilization works. I'm paid to do my work, and I pay
               | others to do their work.
               | 
               | Do you grow your own food and sew your own clothes? Also,
               | did you personally etch the microprocessor that runs your
               | computer? The division of labor inherently means trusting
               | others. So when I buy a bag of M4 screws, I'm not going
               | to measure each screw with a micrometer, and I'm not
               | taking X-ray spectra to verify their material
               | composition.
               | 
               | The academic world also used to trust large publishers to
               | take care to actually review papers. It appears that this
               | trust is now misplaced. But I don't think it was somehow
               | stupid.
        
               | fc417fc802 wrote:
               | You don't seem to be engaging in good faith.
        
               | Calavar wrote:
               | This is a good point. It is not humanly possible to
               | verify every claim you read from every source.
               | 
               | Ideally, you should independently verify claims that
               | appear to be particularly consequential or particularly
               | questionable on the surface. But at some point you have
               | to rely on heuristics like chain of trust (it was peer
               | reviewed, it was published in a reputable textbook), or
               | you will never make forward progress on anything.
        
               | natpalmer1776 wrote:
               | There is a vast difference between a student reading from
               | a textbook and a researcher / scientist reading studies
               | and/or papers.
               | 
               | As a student you are to be directed* in your reading by
               | an expert in the field of study that you are learning
               | from. In many higher level courses a professor will
               | assign multiple textbooks and assign reading from only
               | particular chapters of those textbooks specifically
               | because they have vetted those chapters for accuracy and
               | alignment with their curriculum.
               | 
               | As a researcher and scientist a very large portion of
               | your job is _verifying and then integrating_ the research
               | of others into your domain knowledge. The whole purpose
               | of replicating studies is to look critically at the
               | methodology of another scientist and try as hard as you
               | can to prove them wrong. If you fail to prove them wrong
               | and can produce the same results as them, they have done
               | Good Science.
               | 
               | A textbook is the product of scientists and researchers
               | Doing Science and publishing their results, other
               | scientists and researchers _verifying via replication_ ,
               | and then one of those scientists or researchers who is an
               | expert in the field doing their best to compile their
               | knowledge on the domain into a factually accurate and
               | (relatively) easy to understand summary of the collective
               | research performed in a specific domain.
               | 
               | The fact is that people make mistakes, and the job of a
               | professor (who is an expert in a given field) is to
               | identify what errors have made it through the various
               | checks mentioned above and into circulation, often times
               | making subjective judgement calls about what is 'factual
               | enough' for the level of the class they are teaching, and
               | leverage that to build a curriculum that is sound and
               | helps elevate other individuals to the level of knowledge
               | required to contribute to the ongoing scientific journey.
               | 
               |  _In short, it 's not a bad thing if you're learning a
               | subject by yourself for your own purposes and are not
               | contributing to scientific advancement or working as an
               | educator in higher-education._
               | 
               | * You can self-study, but to become an expert while doing
               | so requires extremely keen discernment to be able to root
               | out the common misconceptions that proliferate in any
               | given field. In a blue-collar field this would be akin to
               | picking up 'bad technique' by watching YouTube videos
               | published by another self-taught tradesman; it's not
               | always obvious when it happens.
        
               | jruohonen wrote:
               | > If you fail to prove them wrong and can produce the
               | same results as them, they have done Good Science.
               | 
               | Not really in my humble opinion. Sure, the Popperian vibe
               | is kind of fundamental, but the whole truncation into
               | binary-valued true/false categories seldom makes sense
               | with many (or even most?) problems for which
               | probabilities, effect sizes, and related things matter
               | more.
               | 
               | And if you fail to replicate a study, they may have still
               | done Good Science. With replications, it should not be
               | about Bad Science and Good Science but about the
               | cumulation of evidence (or a lack thereof). That's what
               | meta-analyses are about.
               | 
               | When we talk about Bad Science, it is about the
               | industrial-scale fraud the article is talking about. No
               | one should waste time replicating, citing, or reading
               | that.
        
               | fc417fc802 wrote:
               | > There is a vast difference between a student reading
               | from a textbook and a researcher / scientist reading
               | studies and/or papers.
               | 
               | Not really. Both are learning new things. Neither has the
               | time or access to resources to replicate even a small
               | fraction of things learned. Neither will ever make direct
               | use of the vast majority of things learned.
               | 
               | Thus both depend on a cooperative model where trust is
               | given to third parties to whom knowledge aggregation is
               | outsourced. In that sense a textbook and prestigious peer
               | reviewed journals serve the same purpose.
        
             | bee_rider wrote:
             | Academia has problems, like everywhere else. But that seems
             | like a big extrapolation from just one professor.
             | 
             | Fake data--you can only get that type of scandal when
             | people are checking the data. I'd be more skeptical of
             | communities that never have that kind of scandal.
        
             | gus_massa wrote:
             | Most of the times you don't "accept" results. You have to
             | build something on them, like an extension or a similar
             | version on other field. So usually the first step is try to
             | understand the cryptic published version and do a
             | reproduction or something as close as possible.
             | 
             | The exact reproductions is never published, because
             | journals don't accept them, but if you add a few tweaks
             | here and there you have a nice seed for an article to
             | publish somewhere.
             | 
             | (I may "accept" an article in a field I don't care, but you
             | probably should not thrust my opinion in fields I don't
             | care.)
        
           | underlipton wrote:
           | Some "fun" reading on the subject of Mr. Maxwell:
           | 
           | https://sarahkendzior.substack.com/p/red-lines
           | 
           | tl;dr He is the bridge that uncomfortably links Biden's
           | former Secretary of State, Antony Blinken, to Jeffrey Epstein
           | and Mossad. Hence, * _gestures at the last couple of weeks
           | and years_ *. Dude was just, like, Fraud Central, apparently.
        
           | canjobear wrote:
           | Peer review existed before 1951 in the US at least. See for
           | example Einstein's reaction to negative reviews when he tried
           | to publish in Physical Review in 1935
           | https://paeditorial.co.uk/post/albert-einstein-what-did-
           | he-t...
        
           | jayde2767 wrote:
           | I wish you had highlighted or bolded "cartel", which is
           | exactly how those industry players act.
        
         | leoc wrote:
         | Right, it seems that many of the weaknesses in the system exist
         | because they serve the interests of journal publishers or of
         | normal, legitimate-ish researchers, but in the process open the
         | door to full-time system-hackers and pure fraudsters.
        
           | bonoboTP wrote:
           | Any system that grows too fast has these kinds of problems.
           | When it's a small intimate circle where everyone knows
           | everyone, reputation alone can keep people in check. Once
           | it's larger you need to invent rules and bureaucracies and
           | structures and you will have loopholes that bad actors can
           | more easily exploit, hiding in the crowd, than in the small
           | version. It's the same with the Internet or computing.
           | Security was much less of a topic when it was mostly honest
           | academic nerds using the Internet, and the protocol designs
           | often didn't even assume adversarial participants. Science
           | also still runs on this assumed honesty system that worked
           | well when it was small.
        
         | ramraj07 wrote:
         | Do you want issues of Nature and cell to be replication
         | studies? As a reader even from within the field, im not
         | interested in browsing through negative studies. It'll be great
         | if I can look them up when needed but im not looking forward to
         | email ToC alerts filled with them.
         | 
         | Also who's funding you for replication work? Do you know the
         | pressure you have in tenure track to have a consistent thesis
         | on what you work on?
         | 
         | Literally every single know that designs academia is tuned to
         | not incentivize what you complain about. Its not just journals
         | being picky.
         | 
         | Also the people committing fraud aren't ones who will say "gosh
         | I will replicate things now!" Replicating work is far more
         | difficult than a lot of original work.
        
           | zhdc1 wrote:
           | > Do you want issues of Nature and cell to be replication
           | studies? As a reader even from within the field, im not
           | interested in browsing through negative studies.
           | 
           | Actually, yes, I do. The marginal cost for publishing a study
           | online at this point is essentially nil.
        
             | recursivecaveat wrote:
             | I think archives with pretty low standards for notability
             | are a good idea. At some point though you have to pick what
             | actually counts as interesting enough to go in the curated
             | list that is actually suggested reading, where the prestige
             | is attached. If there's no curation by Nature then it falls
             | to bloggers or another journal to sift through the fire-
             | hose and make best-of lists. Most of the value is in the
             | curation, not the publishing. Without exclusivity there's
             | very little signal.
        
             | mmooss wrote:
             | > The marginal cost for publishing a study online at this
             | point is essentially nil.
             | 
             | The marginal cost for doing a study remains the same, which
             | is quite a bit. Society doesn't have unlimited scientific
             | talent or hours. Every year someone spends replicating is a
             | year lost to creating something new and valuable.
        
           | Bratmon wrote:
           | > Do you want issues of Nature and cell to be replication
           | studies?
           | 
           | More than anything. That might legitimately be enough to save
           | science on its own.
        
             | dekhn wrote:
             | Maybe nature and cell and a few other journals should be
             | exceptions: they should be the place that the most advanced
             | scientists publish interesting ideas early for the
             | consumption by their competitors. At that level of science,
             | all the competitors can reproduce each other's experiments
             | if necessary; the real value is expanding the knowledge of
             | what seems possible quickly.
             | 
             | (I am not seriously proposing this, but it's interesting to
             | think about distinguishing between the very small amount of
             | truly innovative discovery versus the very long tail of
             | more routine methods development and filling out gaps in
             | knowledge)
        
               | Bratmon wrote:
               | > that level of science, all the competitors can
               | reproduce each other's experiments if necessary
               | 
               | But they don't, and that's the problem!
        
               | dekhn wrote:
               | Advanced groups usually replicate their competitor's
               | results in their own hands shortly after publication (or
               | they just trust their competitor's competence). But they
               | don't spend any time publishing it unless they fail to
               | replicate and can explain why they can't replicate. From
               | their perspective, it's a waste of time. I think this has
               | been shown to be a naive approach (given the high rate of
               | image fraud in molecular biology) but people who are in
               | the top of the field have strong incentives to focus on
               | moving the state of the art forward without expending
               | energy on improving the field as a whole.
        
               | Bratmon wrote:
               | All that makes it more important for top journals to
               | reward replication, not less!
        
               | jltsiren wrote:
               | Top journals are not inherently prestigious. They are
               | prestigious because they try to publish only the most
               | interesting and most significant results. If they started
               | publishing successful replication studies, they would
               | lose prestige, and more interesting journals would
               | eventually rise to the top. (Replication studies that
               | fail to replicate a major result in a spectacular way are
               | another matter.)
        
               | MarkusQ wrote:
               | "strong incentives to focus on moving the state of the
               | art forward without expending energy on improving the
               | field as a whole"
               | 
               | That sort of Orwellian doublethink is exactly the
               | problem. They need to move it forward without improving
               | it, contribute without adding anything, challenge
               | accepted dogma without rocking the boat, and...blech!
        
               | godelski wrote:
               | > challenge accepted dogma without rocking the boat
               | 
               | I think the funniest part is how we have all these heroes
               | of science who faced scrutiny by their peers, but
               | triumphed in the end. They struggled because they
               | challenged the status quo. We celebrate their anti
               | authoritative nature. We congratulate them for their
               | pursuit of truth! And then get mad when it happens. We
               | pretend this is a thing of the past, but it's as common
               | as ever[0,1].
               | 
               | You must create paradigm shifts without challenging the
               | current paradigm!
               | 
               | [0] https://www.scientificamerican.com/article/katalin-
               | karikos-n...
               | 
               | [1] https://www.globalperformanceinsights.com/post/how-a-
               | rejecte...
        
               | godelski wrote:
               | Are you explaining this from experience or from
               | speculation?
               | 
               | I can tell you that it doesn't match my own experience. I
               | also think it doesn't match your example. Those cases of
               | verified image fraud are typically part of replication
               | efforts. The reason the fraud is able to persist is due
               | to the lack of replication, not the abundance of it.
        
               | dekhn wrote:
               | Mostly experience (based on being a PhD scientist, a
               | postdoc, a National Lab scientist, and engineer at
               | several bigtech companies), partly speculation (none of
               | the groups/labs I worked in operated at "the highest
               | level", but I worked adjacent to many of those).
               | 
               | I'm pretty sure most image fraud went completely
               | unrealized even in the case of replication failure. It
               | looks like (pre AI) it was mostly a few folks who did it
               | as a hobby, unrelated to their regular jobs/replication
               | work.
        
               | godelski wrote:
               | In most of the labs I've worked in replication is not a
               | common task[0]                 > 'm pretty sure most
               | image fraud went completely unrealized even in the case
               | of replication failure
               | 
               | Part of my point is that being unable to publish
               | replication efforts means we don't reduce ambiguity in
               | the original experiments. I was taught that I should
               | write a paper well enough that a PhD student (rather than
               | candidate) should be able to reproduce the work. IME
               | replication failures are often explained with "well I
               | must be doing something wrong." A reasonable conclusion,
               | but even if true the conclusion is that the original
               | explanation was insufficiently clear.                 >
               | It looks like (pre AI) it was mostly a few folks who did
               | it as a hobby
               | 
               | I'm sorry, didn't you say                 >>> Advanced
               | groups usually replicate their competitor's results in
               | their own hands shortly after publication
               | 
               | Because your current statement seems to completely
               | contradict your previous one.
               | 
               | Or are you suggesting that the groups you didn't work
               | with (and are thus speculating) are the ones who
               | replicate works and the ones you did work with "just
               | trust their competitor's competence")? Because if this is
               | what you're saying then I do not think this "mostly"
               | matches your experience. That your experience more
               | closely matches my own.
               | 
               | [0] I should take that back. I started in physics
               | (undergrad) and went to CS for grad. Replication could
               | often be de facto in physics, as it was a necessary step
               | towards progress. You often couldn't improve an idea
               | without understanding/replicating it (both theoretical
               | and experimental). But my experience in CS, including at
               | national labs, was that people didn't even run the code.
               | Even when code was provided as part of reviewing
               | artifacts I found that my fellow reviewers often didn't
               | even look at it, let alone run it... This was common at
               | tier 1 conferences mind you... I only knew one other
               | person that consistently ran code.
        
               | dekhn wrote:
               | Note that my field is biophysics (quantitative biology)
               | while yours is physics and CS. Those are done completely
               | differently from biology; with the exception of some
               | truly enormous/complex/delicate experiments that require
               | unique hardware, physics tends to be much more
               | reproducible than biology, and CS doubly-so.
               | 
               | Replication of an experiment and finding image fraud are
               | kind of done as two different things. If somebody
               | publishes a paper with image fraud, it's still entirely
               | possible to replicate their results(!) and if somebody
               | publishes a paper without any image fraud, it's still
               | entirely possible that others could fail to replicate.
               | Also, most image errors in papers are, imho, due to
               | sloppy handling/individual errors, rather than
               | intentional fraud (it's one of the reasons I worked so
               | hard on automating my papers- if I did make an error,
               | there should be audit log demonstrating the problem, and
               | the error should be rectified easily/quickly in the same
               | way we fix bugs in production at big tech).
               | 
               | This came up a bunch when I was at LBL because of work
               | done by Mina Bissell there on extracellular matrix. She
               | is actively rewriting the paradigm but many people can't
               | reproduce her results- complex molecular biology is
               | notororiously fickle. Usually the answer is, "if you're a
               | good researcher and can't reproduce my work, you come to
               | my lab and reproduce it there" because the variables that
               | affect this are usually things in the lab- the
               | temperature, the reagents, the handling.
               | 
               | See https://www.nature.com/articles/503333a (written by
               | Dr. Bissell).
        
               | godelski wrote:
               | > physics tends to be much more reproducible than
               | biology, and CS doubly-so.
               | 
               | With physics I think there is a better culture of
               | reproduction, but that is, I believe, due more to
               | culture. That it is acceptable to "be slow". There's a
               | high stress on being methodical and extremely precise.
               | The prestige is built on making your work bulletproof,
               | and so you're really encouraged to help others reproduce
               | your work as it strengthens it. You're also encouraged to
               | analyze in detail and to faithfully reproduce, because
               | finding cracks also yields prestige. I don't know if it's
               | the money, but no one is in it for the money. Physics
               | sure is a lot harder than anything else I've done and it
               | pays like shit.
               | 
               | For CS the problem is wildly different. It should be easy
               | to reproduce as code is trivial to copy. Ignoring the
               | issue of not publishing code alongside results, there's
               | also often subtle things that can make or break works.
               | I've found many times in replication efforts that the
               | success can rely on a single line that essentially comes
               | form a work that was the reference to a reference of the
               | work I'm trying to reproduce. The problem here is
               | honestly more of laziness. In contrast to physics there's
               | an extreme need for speed. In physics (like everyone else
               | I knew) I often felt like I was not smart enough, and
               | that encouraged people to dive deeper and keep improving
               | or to give up. In CS (like everyone else I knew) I often
               | felt like I was not fast enough, and that encouraged
               | people to chase sponsorships from labs that provided more
               | compute, it encouraged a "shotgun" approach (try
               | everything), or for people to give up (aka "GPU poor").
               | 
               | The reason I'm saying this is because I think it is
               | important to understand the different cultures and how
               | replication efforts differ. In physics a replication
               | failure was often assumed to be due to a lack of
               | intelligence. In CS a replication effort is seen as a
               | waste of time. Both are failures of the scientific
               | process. Science is intended to be self-correcting.
               | Replication is one means of this, but at its heart is the
               | pursuit of counterfactual models. This gives us ways to
               | validate, or invalidate, models through means other than
               | direct replication. You can pursue the consequences of
               | the results if you are unable to pursue the replication
               | itself. This is almost always a good path to follow as it
               | is the same one that leads to the extension and
               | improvement of understanding.
               | 
               | There's a lot I agree and disagree with from Dr Bissell's
               | article. Our perspectives may differ due to our different
               | fields, but I do think it also serves as some a point of
               | collaboration, if not on the subject of meta-science.
               | Biology is not unique in having expensive experiments. I
               | want to point out two famous and large physics projects:
               | the LHC's discovery of the Higgs Boson[0] and LIGO's
               | Observation of a Gravitational Wave[1]. The former has 9
               | full pages of authors (IIRC over 200) while the latter
               | has about 3. These works are both too expensive to
               | replicate while also demonstrating replication. Certainly
               | we aren't going to take another 2 decades to build
               | another CERN and replicate the experiments. But there's
               | an easy to miss question that might also make apparent
               | the existence of replication: who is qualified to review
               | the paper and is not already an author of it? There's
               | definitely some, but it really isn't that many. In these
               | mega projects (and there are plenty more examples) the
               | replication is done through collaboration. Independent
               | teams examine the instruments that make the measurements.
               | Independent teams make measurements, using the same
               | device or different devices (ATLAS isn't the only
               | detector at CERN), different teams independently analyze
               | and process the information, and different teams model
               | and simulate them. With LIGO this is also true. It would
               | be impossible to locate those black holes without at
               | least 2 facilities: one in Hanford (Washington) and the
               | other in Livingston (Louisiana) (and now there's even
               | more facilities). Astrophysics has a long history of this
               | type of replication/collaboration as one team will
               | announce an observation and it is a request for other
               | observations. Observations that often were already made!
               | In HEP (high energy particle physics) this may be less
               | direct, but you'll notice other particle physics labs are
               | in the author list of[0]. That's because despite the
               | exact experiment not being replicatable in other
               | facilities, there are still other experiments done. In
               | the effort to find the Higgs there were many collisions
               | performed at Fermi Lab.
               | 
               | I don't think this same in biophysics, but I think there
               | are nuggets that may be fruitful. Bissell mentions at the
               | end of her argument that she believes replication might
               | have higher success were labs to send scientists to the
               | original labs. I fully agree! That would follow the
               | practice we see in these mega experiments in physics. But
               | I also do think she's brushing off an important factor:
               | it is far quicker and cheaper to replicate works than it
               | is to produce them. You're a scientist, you know how the
               | vast majority of time (and usually the vast majority of
               | money) is "wasted" in failures (it'd be naive to call it
               | waste). Much of this goes away with replication efforts.
               | The greater the collaboration the greater the reduction
               | in time and money.
               | 
               | And I do agree with Bissell in that we probably shouldn't
               | replicate everything[2]. At least if we want to optimize
               | our progress. But also I want to stress that there is no
               | perfect system and there are many roadblocks to progress.
               | Frankly, I'd argue that we waste far more time in things
               | like grant writing and publication revisions. I don't
               | know a single scientist who hasn't had a work rejected
               | due to reviewers either not giving the work enough care
               | or simply because they were unqualified (often working in
               | a different niche so don't understand the minutia of the
               | problem). As for the grant writings, I think they're a
               | necessary evil but I'm also a firm believer of what
               | Mervin Kelly (former director of Bell Labs) said when
               | asked how you manage a bunch of geniuses: "you don't"[3].
               | You're a scientist, an expert in your domain. You already
               | know what directions to look in. You've only gotten this
               | far because you've been honing that skill. We don't have
               | infinite money, so of course we have to have some bar,
               | but we can already sniff out promising directions and
               | we're much better at sniffing out fraud. Science has been
               | designed to be self-correcting.
               | 
               | [More of a side note]                 > Usually the
               | answer is, "if you're a good researcher and can't
               | reproduce my work, you come to my lab and reproduce it
               | there" because the variables that affect this are usually
               | things in the lab- the temperature, the reagents, the
               | handling.
               | 
               | And we should not undermine the importance of these
               | variables. Failures based on them are still informative.
               | They still inform us about the underlying causal
               | structure that leads to success. If these variables were
               | not specified in the paper, then a replication failure
               | shows the mistake of the writing. Alternatively a failure
               | can bound these variables, by making them more explicit.
               | I'm no expert in biophysics, but I'm fairly certain that
               | understanding the bounds of the solution space is
               | important for understanding how the processes actually
               | work.
               | 
               | [0] https://arxiv.org/abs/1207.7214
               | 
               | [1] https://arxiv.org/abs/1602.03837
               | 
               | [2] I also would be very cautious about paid replication
               | efforts. I am strongly against it as well as paywalls on
               | publishing (both in creation of publication as well as
               | the access of).
               | 
               | [3] https://1517.substack.com/p/why-bell-labs-worked
        
               | godelski wrote:
               | The problem is bigger. It even blocks research!
               | 
               | In my own experience I was unable to publish a few works
               | because I was unable to outperform a "competitor"
               | (technically we're all on the same side, right?). So I
               | dig more and more into their work and really try to
               | replicate their work. I can't! Emailing the authors I get
               | no further and only more questions. I submit the papers
               | anyways, adding a section about replication efforts. You
               | guessed it, rejected. With explicit comments from
               | reviewers about lack of impact due to "competitor's"
               | results.
               | 
               | Is an experience I've found a lot of colleagues share.
               | And I don't understand it. Every failed replication
               | should teach us something new. Something about the bounds
               | of where a method works.
               | 
               | It's odd. In our strive for novelty we sure do turn down
               | a lot of novel results. In our strive to reduce
               | redundancy we sure do create a lot of redundancy.
        
               | jltsiren wrote:
               | I've seen this from both sides.
               | 
               | Sometimes the result is wrong, or it's not as big or as
               | general as claimed. Or maybe the provided instructions
               | are insufficient to replicate the work. But sometimes the
               | attempt to replicate a result fails, because the person
               | doing it does not understand the topic well enough.
               | 
               | Maybe they are just doing the wrong things, because their
               | general understanding of the situation is incorrect.
               | Maybe they fail to follow the instructions correctly,
               | because they have subtle misunderstandings. Or maybe they
               | are trying to replicate the result with data they
               | consider similar, but which is actually different in an
               | important way.
               | 
               | The last one is often a particularly difficult situation
               | to resolve. If you understand the topic well enough, you
               | may be able to figure out how the data is different and
               | what should be changed to replicate the result. But that
               | requires access to the data. Very often, one side has the
               | data and another side the understanding, but neither side
               | has both.
               | 
               | Then there is the question of time. Very often, the
               | person trying to replicate the result has a deadline. If
               | they haven't succeeded by then, they will abandon the
               | attempt and move on. But the deadline may be so tight
               | that the authors can't be reasonably expected to figure
               | out the situation by then. Maybe if there is a simple
               | answer, the authors can be expected to provide it. But if
               | the issue looks complex, it may take months before they
               | have sufficient time to investigate it. Or if the initial
               | request is badly worded or shows a lack of understanding,
               | it may not be worth dealing with. (Consider all the bad
               | bug reports and support requests you have seen.)
        
           | benterix wrote:
           | > Do you want issues of Nature and cell to be replication
           | studies?
           | 
           | Of course I do! Not all of course, and taking (subjectively
           | measured) impact into account. "We tried to replicate the
           | study published in the same journal 3 years ago using a
           | larger sample size and failed to achieve similar results..."
           | OR "after successfully replicating the study we can confirm
           | the therapeutic mechanism proposed by X actually works" -
           | these are extremely important results that are takin into
           | account in meta studies and e.g. form the base of policies
           | worldwide.
        
             | smj-edison wrote:
             | Honestly even if they didn't publish the whole paper, if
             | there was just a page that was a table of all the
             | replication studies that were done recently, that would be
             | pretty cool.
        
           | paganel wrote:
           | >Also who's funding you for replication work? Do you know the
           | pressure you have in tenure track to have a consistent thesis
           | on what you work on?
           | 
           | This is partly why much of today's science is bs, pure and
           | simple.
        
           | notRobot wrote:
           | "Original research" isn't worth much unless replicated, which
           | is the entire problem being discussed in this thread.
           | Replicating studies are great though because they tell you if
           | the original research actually stands and is valid.
           | 
           | > Replicating work is far more difficult than a lot of
           | original work.
           | 
           | Only if the original work was BS. And what, just because it's
           | harder, we shouldn't do it?
        
             | ramraj07 wrote:
             | Why blame just the journals when every other system also
             | disintivizes the same.
        
               | anonymars wrote:
               | I must be missing something, surely the argument isn't
               | "other systems also disincentivize solving the problem,
               | therefore we shouldn't work to fix this one"
        
           | renewiltord wrote:
           | Realistically, everyone will say "yes" to the "do you want"
           | question because if you're not a reader or a subscriber you
           | benefit from the readers reading replication studies.
           | 
           | I believe people will enthusiastically say yes but that they
           | do not routinely read that journal.
        
             | andrewprock wrote:
             | Suggesting that people would stop reading Nature if they
             | also included replication studies send like an incredible
             | leap.
        
               | renewiltord wrote:
               | That is a novel interpretation of my comment certainly.
        
               | fc417fc802 wrote:
               | It would directly undermine the reason that people read
               | Nature in the first place.
        
               | MarkusQ wrote:
               | Not really.
               | 
               | "It ain't what you don't know that gets you into trouble.
               | It's what you know for sure that just ain't so."
               | 
               | Knowing that something I thought was true was actually
               | false would have saved me years in several situations.
        
               | fc417fc802 wrote:
               | I didn't understand us to only be talking about failed
               | replication studies of previous Nature papers which would
               | hopefully be few and far between and thus noteworthy
               | indeed. Rather replication studies _in general_ which on
               | average are arguably less interesting to the reader than
               | even the content of the typical archival journal.
        
               | MarkusQ wrote:
               | They certainly will be few and far between when the
               | system is structured to repress them. But there's reason
               | to believe they wouldn't be as rare as you seem to think:
               | 
               | https://www.nature.com/nature/articles?type=retraction
        
               | fc417fc802 wrote:
               | Are you seriously attempting to imply that Nature
               | retractions aren't few and far between?
               | 
               | What's even your point here? Hopefully we are at least in
               | agreement that Nature is seen as prestigious and worth
               | looking through precisely because of the sort of content
               | that they publish. Diluting that would dilute their very
               | nature. (Bad pun very much intended sorry I just couldn't
               | resist.)
        
               | MarkusQ wrote:
               | "Are you seriously attempting to imply that Nature
               | retractions aren't few and far between?"
               | 
               | No. I'm explicitly stating that they are few and far
               | between, but perhaps (not certainly, but conceivably)
               | they shouldn't be.
               | 
               | "What's even your point here?"
               | 
               | My point is that focusing on positive findings and
               | neglecting negative findings perverts the mechanism that
               | makes science work. Science isn't about proving things
               | correct, it's about rooting out errors.
        
               | fc417fc802 wrote:
               | I'm not sure I agree. The system certainly isn't optimal
               | but results aren't just dumped into a vacuum. Something
               | is only useful if people can build on it. Even if
               | negative results don't get published, even if it isn't
               | optimal, by virtue of future positive results building on
               | past things that _did_ reproduce you get forward
               | progress.
               | 
               | Regardless, I don't think that's at odds with my original
               | assertion that becoming a venue for publishing negative
               | results would undermine the "point" of Nature.
               | 
               | The missing link isn't a venue in which to publish. It's
               | funding to do the work in the first place. Also funding
               | to spend the time writing it up when you find that you've
               | inadvertently been tricked into doing the work while
               | trying to get something that builds on it to work.
        
             | RobotToaster wrote:
             | Tagging seems like an option here.
        
           | chocochunks wrote:
           | Even if that negative study could save you one, two, three+
           | years of work for the same outcome (which you then also can't
           | really do anything with)? Shouldn't there BE funding for
           | replication studies? Shouldn't that count towards tenure?
           | Part of the problem is that publications play such a heavy
           | role in getting tenure in the first place.
           | 
           | I'm sure you can more narrowly tune your email alerts FFS.
        
           | peyton wrote:
           | > Do you want issues of Nature and cell to be replication
           | studies?
           | 
           | Hell yeah. We're all trying to get that _Nature_ paper.
           | Imagine if you could accomplish that by setting the record
           | straight.
        
             | fc417fc802 wrote:
             | If you're thoroughly debunking a previous Nature paper they
             | just might publish that. But the expectation is that you'll
             | succeed. Publishing that sort of mundane article would
             | reduce the prestige of getting something into the journal.
             | Publishing in a high impact journal is only seen as an
             | achievement in the first place because of what it implies
             | about the content of your paper.
        
           | xandrius wrote:
           | I know you got a ton of responses already but not caring
           | about replicability just invalidates science as a method. If
           | we care only about first to publish we end up in the current
           | situation where we don't even know that we know is actually
           | even remotely correct.
           | 
           | All because journals prefer novelty over confirmation. It's
           | like a castle of cards, looks cool but not stable or long-
           | term at all.
        
           | lovich wrote:
           | > Replicating work is far more difficult than a lot of
           | original work.
           | 
           | I don't regularly read scientific studies but I've read a few
           | of them.
           | 
           | How is it possible that a serious study is harder to
           | replicate than it is to do originally. Are papers no longer
           | including their process? Are we at the point where they are
           | just saying "trust me bro" for how they achieved their
           | results?
           | 
           | > Do you want issues of Nature and cell to be replication
           | studies?
           | 
           | Not issues of Nature but I've long thought that universities
           | or the government should fund a department of "I don't
           | believe you" entirely focused on reproducing scientific
           | results and seeing if they are real
        
             | fc417fc802 wrote:
             | > How is it possible that a serious study is harder to
             | replicate than it is to do originally.
             | 
             | They aren't. GP was on point until that last sentence. Just
             | pretend that wasn't there. It's pretty much always much
             | easier to do something when all the key details have been
             | figured out for you in advance.
             | 
             | There is some difficulty if something doesn't work to
             | distinguish user error from ambiguity of original
             | publication from outright fraud. That can be daunting. But
             | the vast majority of the time it isn't fraud and simply
             | emailing the original author will get you on track. Most
             | authors are overjoyed to learn about someone using their
             | work. If you want to be cynical about it, how else would
             | you get your citation count up?
        
           | carlosjobim wrote:
           | If you're a reader within the field, then you are the one
           | person in the world who should be most interested in negative
           | replication studies.
        
         | dheera wrote:
         | Mainstream journals are complicit, but are not the biggest
         | problem.
         | 
         | The biggest problem by far is modern society: Tenure, getting
         | paid a livable wage as a researcher, not getting stack-ranked
         | and eliminated from your organization all overindex on positive
         | research results that are marketable. This "loss function"
         | encourages scientific fraud of sorts.
        
           | bonoboTP wrote:
           | When, in those mythical non-"modern" times, was it easy to
           | get tenure or a livable wage as a researcher? How open were
           | the doors to this and what proportion of society got a
           | realistic chance to pursue such a career? More people getting
           | a chance means more fierce competition.
        
         | canjobear wrote:
         | This isn't about honest researchers resorting to fraud to
         | publish their null results because they were blocked by big bad
         | Nature. It's about journals and authors churning out pure junk
         | papers whose only goal is to game metrics like citation count.
        
         | godelski wrote:
         | > Most will refuse to publish replications, negative studies,
         | or anything they deem unimportant, even if the study was
         | conducted correctly.
         | 
         | I think this was really caused by the rise of bureaucracy in
         | academia. Bureaucrats favorite thing is a measurement,
         | especially when they don't understand its meaning. There's
         | always been a drive for novelty in academia, it's just at the
         | very core of the game. But we placed far too much focus on
         | this, despite the _foundation_ of science being replication. We
         | made a trade, foundation for (the illusion of) progress. It 's
         | like trying to build a skyscraper higher and higher without
         | concern for the ground it stands on. Doesn't take a genius to
         | tell you that building is going to come crashing down. But
         | proponents say "it hasn't yet! If it was going to fall it would
         | have already" while critics are actually saying "we can't tell
         | you when it'll fall, but there's some concerning cracks and
         | we're worried it'll collapse and we won't even be able to tell
         | we're in a pile of rubble."
         | 
         | I don't know what the solution is, but I do know that our fear
         | of people wasting money and creating fraudulent studies has
         | only resulted in wasting money and fraudulent studies. We've
         | removed the verification system while creating strong
         | incentives to cheat (punish or perish, right?).
         | 
         | I think one thing we do need to recognize is that in the grand
         | scheme of things, academia isn't very expensive. A small
         | percentage of a large number is still a large number. Even if
         | half of academics were frauds it would be a small percentage of
         | waste, and pale in comparison to more common waste, fraud, and
         | abuse of government funds.
         | 
         | From what I can tell, the US spent $60bn for University R&D in
         | 2023[0] (less than 1% of US Federal expenditures). But in that
         | same time there was $400bn in waste and fraud through Covid
         | relief funds [1]. With $280bn being straight up fraud. That
         | alone is more than 4x of all academic research funding!!!
         | 
         | I'm unconvinced most in academia are motivated by money or
         | prestige, as it's a terrible way to achieve those things. But I
         | am convinced people are likely to commit fraud when their
         | livelihoods are at stake or when they can believe that a small
         | lie now will allow them to continue doing their work. So as I
         | see it, the publish or perish paradigm only promotes the
         | former. The lack of replication only allows, and even
         | normalizes, the latter. The stress for novelty only makes
         | academics try to write more like business people, trying to
         | sell their product in some perverse rat race.
         | 
         | So I think we have to be a bit honest here. Even if we were to
         | naively make this space essentially unregulated it _couldn 't_
         | be the pinnacle of waste, fraud, and abuse that many claim it
         | is. But I doubt even letting scientists be entirely free from
         | publication requirements that you'd find much waste, fraud, and
         | abuse. Science has a naturally regulating structure. It was
         | literally created to be that way! We got to where we are in
         | through this self regulating system because scientists love to
         | argue about who is right and the process of science is meant to
         | do exactly that. Was there waste and fraud in the past? Yes. I
         | don't think it's entirely avoidable, it'll never be $0 of waste
         | money. But the system was undoubtably successful. And those
         | that took advantage of the system were better at fooling the
         | public than they were their fellow scientists. Which is
         | something I think we've still failed to catch onto
         | 
         | [0] https://usafacts.org/articles/what-do-universities-do-
         | with-t...
         | 
         | [1] https://apnews.com/article/pandemic-fraud-waste-billions-
         | sma...
        
           | bonoboTP wrote:
           | You either have something documented and quantified and
           | measured and objective criteria tickboxes and deal with this
           | style of failure mode, or you rely on subjective judgment and
           | assessment and accept the failure mode of bias, nepotism, old
           | boy's clubs etc. Of course the ideal case is to rely on the
           | unbureaucratic informal wise and impartial judgment of some
           | hypothetical perfect humans you can fully trust and rely on,
           | and they always decide fully on merits etc. without having to
           | follow any rigid criteria and checkboxes and numbers on
           | hiring and promotion etc. But people are not perfect and
           | society largely decided to go the bureaucratic way to ensure
           | equal opportunities and to reduce bias through this kind of
           | transparency.
        
             | godelski wrote:
             | > You either have something documented and quantified and
             | measured and objective criteria tickboxes and deal with
             | this style of failure mode, or you rely on subjective
             | judgment and assessment and accept the failure mode of
             | bias, nepotism, old boy's clubs etc
             | 
             | My argument is that our current pursuit of the former only
             | reinforces the existence of the latter.
             | 
             | You have a fundamental flaw in your argument, one that
             | illustrates a common, yet fundamental, misunderstanding of
             | science. There is no "objective" thing to measure, there
             | are only proxies. I actually recently stumbled on a short
             | by Adam Savage that I think captures this[0], although I
             | think he's a bit wrong too. Regardless of precision we are
             | always using a proxy. A tape measure does not define a
             | meter, it only serves as a reference to compare with. A
             | reference where not only the human makes error when
             | reading, but that the reference itself has error[1]. So
             | there are no direct measurements, there are only
             | measurements by proxy.
             | 
             | You may have heard someone say "science doesn't prove
             | things, it disproves them", and that's in part a
             | consequence to this. Our measurements are meaningless
             | without an understanding of their uncertainty (both
             | quantifiable and unquantifiable!) as well as the
             | assumptions they are made under.
             | 
             | I'm not trying to be pedantic here, I think this precision
             | in understanding matters to the conversation. My argument
             | is that by discounting those errors that they accumulate.
             | We've had a pretty good run. This current system has only
             | really started to be practiced in the 60s and 70's. So 50
             | years is a lot of time for error to accumulate. 50 years is
             | a lot of time for small, seemingly insignificant, and easy
             | to dismiss errors to accumulate into large, intangible, and
             | complex problems.
             | 
             | There's something that I guess is more subtle in my
             | argument: science is self-correcting. I don't mean
             | "science" as the category of pursuits that seek truths
             | about the world around us, but I mean "science" as a
             | systematic approach to obtaining knowledge. A key reason
             | this self-correction happens is due to replication. But in
             | reality that is a consequence of how we pin down truth
             | itself. We seek causal structures. More specifically, we
             | seek counterfactual models. Assuming honest practitioners,
             | failures of reproduction happen for primarily for one of
             | two reasons: 1) ambiguity of communication between the
             | original experimenters and those replicating or 2) a
             | variation in conditions. 2) is actually quite common and
             | tells us something new about that causal structure. In
             | practice it is extremely difficult, if not impossible, to
             | exactly replicate the conditions of the original
             | experiment, so even with successful replication we gain
             | information about the robustness of the results.
             | 
             | But why am I talking about all this? Because without the
             | explicit acknowledgement of these limitations we seem to
             | easily forget them. We are often treating substantially
             | more subjective measures (such as impact or novelty) as far
             | more objective than we would treat even physical
             | measurements. It should be absolutely no surprise that
             | things like impact are at best extremely difficult to
             | measure. Even with a time machine we may not accurately
             | measure the impact of a work for decades, or more.
             | Ironically, a major reason for a work's impact to be found
             | only after decades (or centuries) is the belief that at its
             | time it had no impact, and was a dead end. You'd be amazed
             | at how common this actually is. It's where jokes similar to
             | how everything is named after the second person to discover
             | something, the first being Euler[2]. But science is self-
             | correcting. Even if a discovery of Euler's was lost, it is
             | only a matter of time before someone (independently)
             | rediscovers it.
             | 
             | I'm talking about this because there is no perfect system.
             | Because a measurement without the acknowledge of its
             | uncertainty is far less accurate than a measurement with.
             | I'm talking about this because we will always have errors
             | and the existence of them is not a reason to dismiss
             | things. Instead we have to compare and contrast both the
             | benefits and limits of competing ideas. We are only doing
             | ourselves a disservice by pretending the limits don't
             | exist. And if we mindlessly pursue objective measurements
             | we'll only end up finding we've metric hacked our way into
             | reading tea leaves. As we advance in any subject the
             | minutia always ends up being the critical element (see [0])
             | and so the problem is it doesn't matter if we're 90%
             | "objective" and 10% reading the tea leaves. Not when the
             | decisions are made differentiating the 10%. In reality
             | we're not even good at measuring that 90% when it comes to
             | determining how productive academics are[3-5]
             | 
             | [0] https://www.youtube.com/shorts/JGa_X4QfE-0
             | 
             | [1] https://www.youtube.com/watch?v=EstiCb1gA3U
             | 
             | [2] https://en.wikipedia.org/wiki/List_of_topics_named_afte
             | r_Leo...
             | 
             | [3] https://briankeating.substack.com/p/peter-higgs-
             | wouldnt-get-...
             | 
             | [4] https://yoshuabengio.org/2020/02/26/time-to-rethink-
             | the-publ...
             | 
             | [5] See the two links in this comment as further evidence.
             | They are about relatively recent Nobel works that faced
             | frequent rejections
             | https://news.ycombinator.com/item?id=47340733
        
               | bonoboTP wrote:
               | Someone has to pay for all this. That someone is most
               | often not a scientist themselves. They don't have a that
               | vague intuitive research taste that scientists have.
               | Beyond fairly trivial levels of technical correctness,
               | the value of research lies in its narrative implications,
               | its interestingness, its surprise factor etc. These are
               | not objective and are often more about aesthetics and
               | taste than popularly understood. Why does the research
               | matter? To whom does it matter? Are those people
               | important? Do they control resources?
        
         | bonoboTP wrote:
         | Plenty will publish it, but those are not as highly regarded by
         | the community. It's not a problem of journals. It's not hard to
         | start your own journal by teaming up with other academics. In
         | machine learning, ICLR is such a venue for example. The problem
         | is much deeper and more fundamental. You want to publish
         | alongside groundbreaking novel research. Researcher's own ears
         | perk up when they hear about something new. They invite
         | colleagues to talk about their novel discoveries not to
         | describe all their null results and successful replications of
         | known results. Funding agencies want research with novelty and
         | impact. They want to write reports to the higher ups and the
         | politicians and the donors that document the innovations that
         | their funding brought. The media will republish press releases
         | that have cool new results.
         | 
         | To have research happening, you need someone saying "I want to
         | give money to this researcher". There is an endless queue of
         | people lining up who are ready to take this money and do
         | something with it. The person with money (govt or private) has
         | to use some heuristics to pick. One way is to say "I trust this
         | one, I don't care too much what the project is, I'm sure this
         | person will do something that makes sense". But that is
         | dependent on a track record.
        
         | obviouslynotme wrote:
         | I have worked in this particular sausage factory. Multiple
         | funded random replications are the only thing that will save
         | science from this crisis. The scientific method works. We need
         | to actually do it.
         | 
         | Replications don't have to be in the journals either. As long
         | as money flows, someone will do them, and that is what matters.
         | The randomization will help prevent coordination between
         | authors and replicators.
         | 
         | In a better world, negative studies and replications would
         | count towards tenure, but that is unlikely to occur. At least
         | half of the problem is the pressure to continuously publish
         | positive results.
        
           | bonoboTP wrote:
           | Regardless of what gets taught in school about science being
           | objective and without ego, or having a culture of adversarial
           | checks on each other etc., the reality is that scientists are
           | humans and have egos and have petty feuds.
           | 
           | Publishing a failed replication of the work of a colleague
           | will not earn you many brownie points. I'm stating this as an
           | observation of what is the case, not as something that I
           | think should be the case. If you attack other researchers
           | like this and damage their reputation - even if for valid
           | scientific reason - you'll have a hard time when those
           | colleagues sit on committees deciding about your next grant
           | etc.
           | 
           | Of course if you discover something truly monumental that
           | will override this. But simply sniping down the mediocre
           | research published by other run-of-the-mill researchers will
           | get you more trouble than good. Yes it's directly in
           | contradiction to the textbook-ideal of what science should
           | be, as described to high school students, but there are many
           | things in life this way.
           | 
           | Of course it can be laudable to go on such a crusade despite
           | all this, and to relentlessly pursue scientific truth, etc.
           | but that just won't scale.
        
             | obviouslynotme wrote:
             | You are absolutely correct. Even distributing the
             | replication around the world will only help so much. It's a
             | small world out there and only smaller in the
             | specializations.
             | 
             | That's why replication has to be required and standard. It
             | will hurt to tear off the bandaid, but once the culture
             | shifts, people will hesitate to publish mediocre research
             | in the first place. Without mediocre research flooding the
             | zone, real numbers will dominate and inflated expectations
             | will wither.
        
       | temporallobe wrote:
       | My wife completed her PhD two years ago and she put a LOT of work
       | into it. Many sleepless nights, and it almost destroyed our
       | marriage. It took her about 6 years of non-stop madness and she
       | didn't even work during that time. She said that many of her
       | colleagues engaged in fraudulent data generation and sometimes
       | just complete forgery of anything and everything. It was obvious
       | some people were barely capable of putting together coherent
       | sentences in posts, but somehow they generated a perfect
       | dissertation in the end. It was common knowledge that candidates
       | often hired writers and even experts like statisticians to do
       | most of the heavy lifting. I don't know if this is the norm now,
       | but I simultaneously have more respect and less respect for those
       | doctoral degrees, knowing that some poured their heart and soul
       | into it, while others essentially cheated their way through.
       | OTOH, I also understand that there may be a lot of grey area.
       | 
       | My eyes have been opened!
        
         | titzer wrote:
         | I found the article and your third-hand anecdotes troubling.
         | The good news is that it does not match _any_ of the years of
         | experience in my field. Fraud is just not that rampant. At PhD-
         | granting institutions, the level of fraud you describe here is
         | very seriously punished. It 's career-ending. The violations
         | that you are serious enough that any institution would expel
         | said students (or harshly punish faculty--probably firing
         | them). She did no one any favors by not reporting them.
         | 
         | Unfortunately I don't think a dialogue around vague anecdotes
         | is going to be particularly enlightening. What matters is
         | culture, but also process--mechanisms and checks--plus
         | consequences. Consequences don't happen if everyone is hush-
         | hush about it and no one wants to be a "rat".
        
           | qsera wrote:
           | >It's career-ending..
           | 
           | That is where being good at politics come into play. And if
           | you are good at it, instead of being career-ending, fraud
           | will put you in the highest of the positions!
           | 
           | No one wants a "plant" who cannot navigate scrutiny!
        
           | delichon wrote:
           | > The good news is that it does not match any of the years of
           | experience in my field.
           | 
           | I worked for exactly one academic, and he indulged in
           | impossible-to-detect research fraud. So in my own limited
           | experience research fraud was 100%.
           | 
           | It was a biology lab, and this was an extremely hard working
           | man. 18 hours per day in the lab was the norm. But the data
           | wasn't coming out the way he wanted, and his career was at
           | stake, so he put his thumb on the scale in various ways to
           | get the data he needed. E.g. he didn't like one neural
           | recording, so he repeated it until he got what he wanted and
           | ignored the others. You would have to be right in the middle
           | of the experiment to notice anything, and he just waved me
           | off when I did.
           | 
           | This same professor was the loudest voice in the department
           | when it came to critiquing experimental designs and
           | championing rigor. I knew what he did was wrong, because he
           | taught me that. And he really appeared to mean it, but when
           | push came to shove, he fiddled, and was probably even lying
           | to himself.
           | 
           | So I came away feeling that academic fraud is probably
           | rampant, because the incentives all align that way. Anyone
           | with the extraordinary integrity to resist was generally
           | self-curated out of the job.
        
             | dekhn wrote:
             | I had a somewhat similar experience- was a postdoc for a
             | pre-tenure professor at berkeley. after writing up a paper
             | based on her methods, with poor results, I handed the draft
             | to her. She rewrote it- basically adding carefully
             | worded/presented results that made it look as good as
             | possible. And then submitted it (to a niche conference
             | where the editor was a buddy of hers). When I read her
             | submission I asked her to remove my name from it and she
             | immediately withdrew the submission. I left her lab shortly
             | after because I am not going to tarnish my publication
             | record with iffy papers like that.
             | 
             | Over time I learned that most papers in my field
             | (computational biology) are embellished to some extent or
             | another (or cherry-picked/curated/structured for success)
             | and often irreproducible- some key step is left out, or no
             | code is provided that replicates the results, etc. I can
             | see this from two perspectives:
             | 
             | 1) science should be trivially reproducible; it should not
             | require the smartest/most capable people in the field to
             | read the paper and reproduce the results. This places a
             | burden on the people who are at the state of the art of the
             | field to make it easy for other folks, which slows them
             | down (but presumably makes overall progress go faster).
             | 
             | 2) science should be done by geniuses; the leaders in the
             | field don't need to replicate their competitors paper. it's
             | sufficient to read the paper, apply priors, and move on
             | (possibly learning whatever novel method/technique the
             | paper shows so they can apply it in their own hands). It
             | allows the field innovators to move quickly and discover
             | new things, but is prone to all sorts of
             | reliability/reproducibility problems, and ideally science
             | should be egalitarian, not credentials-based.
        
             | renewiltord wrote:
             | My cousin (with whom I am very close) had a similar
             | experience that I posted about years ago.
             | https://news.ycombinator.com/item?id=32969092
             | 
             | I have repeated it many times on this site but here's the
             | reality of human experience: if the rate of fraudulent labs
             | is even as high as 10% you should expect that any viewpoint
             | that it's widespread would be drowned out by views that
             | it's not real.
             | 
             | Also, the phenomenon you observed where people are
             | champions till the rubber meets the road is more common
             | than one thinks.
        
               | Noumenon72 wrote:
               | > if the rate of fraudulent labs is even as high as 10%
               | you should expect that any viewpoint that it's widespread
               | would be drowned out by views that it's not real.
               | 
               | If "it" is fraud here I would expect the viewpoint that
               | it's widespread to be less and less drowned out as it
               | approached 10% since everyone would know that it's real.
               | I think I'm misunderstanding the sentence.
        
               | renewiltord wrote:
               | No, the guys at fraudulent labs and the guys at honest
               | labs will both claim no fraud. The only ones who will
               | claim fraud are those who cross over. So you'll get a
               | vast majority telling you it's not happening and a tiny
               | minority (even when as high as 10% are fraud) telling you
               | the fact. All rare things have this effect. There will be
               | so many people telling you it's not real "as someone in
               | the field". They will be adamant about it. You need
               | someone who has seen both.
               | 
               | To be clear, not "as it approaches 10%". I mean "even as
               | high as 10%".
        
         | mistrial9 wrote:
         | yeah - skeptical here. Among certain departments, at large
         | schools, under certain leaders.. The combination of "my
         | marriage almost crumbled" for motivated reasoning, and "I have
         | never seen any of this before" total inexperience with actual
         | process.. the post shows itself to be biased and unreliable.
         | 
         | However, among certain departments, at large schools, under
         | certain leaders.. yes, and growing
         | 
         | $0.02
        
         | russdill wrote:
         | Fucking hilarious to me when people claim academics are
         | motivated by the "money", eg, when claimed by climate deniers.
        
           | 1234letshaveatw wrote:
           | Undoubtably climate science is the exception and immune from
           | fraudulent data generation and sometimes complete forgery
        
             | russdill wrote:
             | I'm sure there's some, but the small point here is that it
             | almost certainly is more motivated by factors other than
             | financial gain. I'm sure it you search you can find such
             | cases though.
             | 
             | The much broader point though is the dismissal of the bulk
             | consensus of academic research because academics are in it
             | for the "money".
        
         | suddenlybananas wrote:
         | What field? I am aware this kind of stuff happens, but I don't
         | really see it among any of my colleagues.
        
       | fastaguy88 wrote:
       | It is useful to distinguish between "effective" scientific fraud,
       | where some set of fraudulent papers are published that drive a
       | discipline in an unproductive direction, and "administrative"
       | scientific fraud, where individuals use pseudo-scientific
       | measures (H-index, rankings, etc) to make allocation decisions
       | (grants, tenure, etc). This article suggests that administrative
       | scientific fraud has become more accessible, but it is very
       | unclear whether this is having a major impact on science as it is
       | practiced.
       | 
       | Non-scientists often seem to think that if a paper is published,
       | it is likely to be true. Most practicing scientists are much more
       | skeptical. When I read a that paper sounds interesting in a high
       | impact journal, I am constantly trying to figure out whether I
       | should believe it. If it goes against a vast amount of science
       | (e.g. bacteria that use arsenic rather than phosphorus in their
       | DNA), I don't believe it (and can think of lots of ways to show
       | that it is wrong). In lower impact journals, papers make claims
       | that are not very surprising, so if they are fraudulent in some
       | way, I don't care.
       | 
       | Science has to be reproducible, but more importantly, it must be
       | possible to build on a set of results to extend them. Some
       | results are hard to reproduce because the methods are technically
       | challenging. But if results cannot be extended, they have little
       | effect. Science really is self-correcting, and correction happens
       | faster for results that matter. Not all fraud has the same
       | impact. Most fraud is unfortunate, and should be reduced, but has
       | a short lived impact.
        
         | qsera wrote:
         | >methods are technically challenging.
         | 
         | And finanacially too..
         | 
         | >Science really is self-correcting..
         | 
         | When economy allows it....
        
         | perfmode wrote:
         | The distinction between effective and administrative fraud is
         | useful and I think underappreciated. A lot of the conversation
         | in these threads conflates the two, which makes it hard to
         | reason about what actually needs fixing.
         | 
         | I want to push back a little on "science is self-correcting"
         | though. It's true in the limit, but correction has a latency,
         | and that latency has real costs. In fields like nutrition,
         | psychology, or pharmacology, a fraudulent or deeply flawed
         | result can shape clinical guidelines, public policy, and drug
         | development pipelines for a decade or more before the
         | correction lands. The people harmed during that window don't
         | get made whole by the eventual retraction.
         | 
         | The comparison I keep coming back to is fault tolerance in
         | distributed systems. You can build a system that's "eventually
         | consistent" and still have it be practically broken if
         | convergence takes too long or if bad state propagates faster
         | than corrections do. The fraud networks described in TFA are
         | basically an adversarial workload against a system (peer
         | review) that was designed for a much lower rate of bad input.
         | Saying the system self-corrects is accurate, but it's not the
         | same as saying the system is healthy or that the current
         | correction rate is adequate.
         | 
         | I think the practical question isn't whether science corrects
         | itself in theory but whether the feedback loops are fast enough
         | relative to the rate of fraud production, and right now the
         | answer seems pretty clearly no.
        
       | pfdietz wrote:
       | One approach is more integration of researchers with businesses.
       | Fraud (or simple incompetence) by researchers negatively affects
       | businesses, as they expend effort on things that aren't real. I
       | understand this is a constant problem in the pharmaceutical
       | industry.
        
         | robmccoll wrote:
         | It's quite possible to be very successful marketing and selling
         | things that aren't real. The market consists of humans, not
         | perfectly rational machines.
        
       | stanford_labrat wrote:
       | the problem is two-fold in my opinion.
       | 
       | firstly, there are basically no _legal_ repercussions for
       | scientific misconduct (e.g. falsifying data, fake images, etc.).
       | most individuals who are caught doing this get either 1) a slap
       | on the wrist if they are too big to fail or in the employ of
       | those who are too big to fail or 2) disbarred, banned, and lose
       | their jobs. i don 't see why you can go to jail for lying to
       | investors about the number of users in your app but don't go to
       | jail for lying to the public, government, and members of the
       | scientific community about your results.
       | 
       | secondly, due to the over production of PhD's and limited number
       | of professorship slots competition has become so incredibly
       | intense that in order to even be considered for these jobs you
       | _must_ have Nature, Cell, and Science papers (or the field
       | equivalent). for those desperate for the job their academic
       | career is over either way if they caught falsifying data or if
       | they don 't get the professorship. so if your project is not
       | going the way you want it to then...
       | 
       | sad state of things all around. i've personally witnessed enough
       | misconduct that i have made the decision to leave the field
       | entirely and go do something else.
        
         | noslenwerdna wrote:
         | I unironically agree, p-hacking should be a criminal offense.
        
       | pjdesno wrote:
       | Perhaps relevant to this - if you go to this global ranking of
       | publications:
       | https://traditional.leidenranking.com/ranking/2025/list
       | 
       | and select "Mathematics and Computer Science", you'll find the
       | top-ranked university is the University of Electronic Science and
       | Technology of China.
       | 
       | My Chinese colleagues have heard of it, but never considered it a
       | top-ranked school, and a quick inspection of their CS faculty
       | pages shows a distinct lack of PhDs from top-ranked Chinese or US
       | schools. It's possible their math faculty is amazing, but I think
       | it's more likely that something underhanded is going on...
        
       | Atlas667 wrote:
       | Almost as if capitalism makes everything into a market, and the
       | profits make it self sustaining.
       | 
       | How many will see the connections between this and our capitalist
       | mode of production? Probably few since modern lit/news is
       | allergic to systemic analysis.
       | 
       | The blatant flaws of capitalism can't be ignored for much longer.
        
         | pooooka wrote:
         | What I get from this is that the professional academic
         | community -- as a whole -- has hit critical mass, which has
         | produced a cottage industry of paper mills and fraudulent
         | services to support said surplus.
         | 
         | Socialism wouldn't be the answer to this because socialism is
         | famous for struggling with surpluses and shortages. All
         | socialism would do is clamp down (hard) on academic's, which
         | case you wind up with the famous shortage where not enough
         | PHD's are available to produce research for an industry.
         | 
         | And that's not a problem specific to just socialism, that's the
         | fallacy of central-planning. The US government clamped down on
         | welfare fraud and the result were freak government social
         | workers sniffing people's bed sheets and rooting through
         | drawers and forcing everyone to document partners.
         | 
         | This is the situation where there needs to be a market
         | correction because the alternative could be far worse.
        
           | Atlas667 wrote:
           | It's the tax-payer funded business model, the NGO trap.
           | Subsidies, grants, tax-breaks, credit, deductions,
           | exemptions, etc. A whole class of profiteers live in this
           | sector. Even though academia funding isn't strictly
           | categorized as an NGO, it still fits/foots the bill. Public
           | funding of private gains is the oldest trick in the book. Ask
           | any capitalist, they know. And I'm not saying I'm against
           | public funding, but this is often codified into a mafia of
           | sorts when enough money flows through.
           | 
           | The real problem here is the fundamental lack of democratic
           | control over our agencies. That our political organization is
           | intensely lagging behind our productive organization. That
           | our whole political will involves TRUSTING strangers to not
           | be corrupt instead of directly democratizing these processes
           | as much as possible.
           | 
           | But besides that, you cannot remove history from historical
           | analysis. The reason socialism countries struggled in the
           | beginning wasn't an inherent flaw in its organization, but
           | the fact that they were under constant war war by capitalist
           | countries through out their existence. Also keep in mind that
           | most socialist countries did NOT have a whole section of the
           | world where-from to extract riches through murder (S.America,
           | Africa, Middle east, etc), like western capitalist countries
           | had. This is convenient for you to ignore. Maybe because you
           | don't know, or don't care about the super-exploitative
           | history of these places and how they tie into western
           | capitalism. But they are inherent to western wealth and these
           | countries' whole history is struggle against this
           | exploitation.
           | 
           | Not to mention that most of the countries on earth are
           | capitalists and are very very very poor.
           | 
           | To add: Socialism has nothing to do with "clamping down" on X
           | or Y industry, as you hypothetically claim would happen.
           | Socialism is almost exclusively about removing the need to
           | generate capital from production. It unleashes production
           | from its historical ball and chain that is profiteering.
           | 
           | In a single sentence: Instead of production being held back
           | by capitalists generating wealth we can produce for our own
           | needs. It is self sustaining production.
           | 
           | Central planning is not fallacious. Your problem is with
           | corruption, not democratic central planning. The US Govt is a
           | pro-capitalist entity that pro-capitalists try to distance
           | themselves from (ironically). So using them as an example
           | isn't saying anything at all.
           | 
           | Central planning is not "allow a small group of people to
           | decide things", as happens in the US Govt. Central planning
           | is to take into account all sources of information on
           | production to plan said production democratically.
           | 
           | This will always beat the highly highly inefficient
           | speculation of capitalism. Where trillions vanish on a whim
           | and cause of a tweet, where crisis occur every 8-10 years,
           | and where its whole trade market is built to hide that it is
           | mostly insider trading. Again, your problem is with
           | corruption not democratic central planning.
           | 
           | And the way to deal with corruption is to create more
           | democratic bodies where avg people hold real power. I don't
           | see you asking for that either. We call that socialism.
        
         | orbital-decay wrote:
         | All people in my extended family were Soviet scientists and
         | engineers from multiple fields, and outside of experimental
         | physics it was the same or worse. Same publish or perish
         | pressure, same amount of fraud and lack of reproducibility. A
         | ton of papers were made up. My father's lab lead was an
         | absolute fraud (biochemistry), everybody knew that, and my
         | father was unable to speak up until the late 90's.
         | 
         | When I was a kid I thought it was the issue with USSR rotting
         | to the core (it was), but when it crashed and later when the
         | web appeared, it became obvious that it's a common problem with
         | academia and its incentives.
        
       | pmarreck wrote:
       | why would anyone actually interested in scientific research come
       | to this, since it literally undermines the whole practice of
       | science?
        
         | cyberjerkXX wrote:
         | Publish or perish. Academia requiring PhDs to publish or be
         | fired. It's made entire fields echo chambers and prone to
         | political influence.
        
           | pmarreck wrote:
           | so a perverse incentive, basically. shocker. got it
        
       | zahlman wrote:
       | It's strange to me that in places full of smart people, it seems
       | to be well understood that this happens and there are lots of
       | anecdotes relating to it; yet the same people will be confused
       | that their political adversaries don't trust "the science" on one
       | issue or another.
       | 
       | Maybe it's the scien _tists_ they don 't trust?
        
         | Hendrikto wrote:
         | That's the beautiful thing about science: You do not have to
         | (and should not) trust any individual. And even if you don't
         | trust "the consensus" of "the scientific community", you can
         | empirically verify yourself.
        
           | zahlman wrote:
           | Can ordinary civilians feasibly measure, for example, global
           | trends in mean temperature without relying on the data of
           | others?
        
             | fc417fc802 wrote:
             | No, but the literature is open for you to read. Thus you
             | can judge the stated reasoning for yourself. You can also
             | assess how many independent groups are making the same (or
             | closely related) claim.
             | 
             | If only one person claims X then it might be fraud. If
             | large numbers of seemingly unrelated people all claim X
             | then you're forced to decide between X and a global
             | conspiracy to misrepresent X.
             | 
             | To your example. Importantly, even if you deemed one of the
             | global mean temperature datasets to be untrustworthy there
             | are other related (but different) datasets. There are also
             | other pieces of evidence related to the downstream claims
             | that don't look directly at temperature.
        
           | dekhn wrote:
           | Are you going to build a competitor to CERN?
           | 
           | There are many things that cannot be feasibly verified
           | empirically without access to rare resources.
        
           | tbrownaw wrote:
           | Once you move from abstract to practical - like say having
           | legislators or regulators make rules based on The Science, or
           | relying personally on more facts than you have time to
           | independently verify - yes you do need to have trustworthy
           | people.
        
         | bonoboTP wrote:
         | I think it's difficult to relay to the public that a lot of
         | this noise in "scientific publications" is not the same
         | category as real research by reputable institutions. Yes, in
         | certain cases the line can be blurry, fraudsters are sometimes
         | caught in big-name institutions, maybe more in some fields than
         | others, but serious researchers of the field know very well
         | which publication venues and research groups are the real deal
         | and what is bullshit. Overwhelmingly, these fraud papers and
         | nonsense LLM-generated fake stuff are not published in serious
         | journals or conferences.
         | 
         | It's a bit like how can we trust online shopping if I get all
         | these emails trying to sell me aphrodisiac pills?
        
       | gadders wrote:
       | This is what happens when people argue past each other on "Trust
       | the science".
       | 
       | Science is good, but it's mediated via corruptible humans.
        
         | MarkusQ wrote:
         | Also, "science" isn't some sort of dogma that you should trust,
         | it's a process you should follow.
         | 
         | "Trust the science" is anathema to the process. If anything,
         | the chant should be "Doubt the science! Give it your best shot,
         | refute it with data, with logic, provide a better explanation!"
        
           | bonoboTP wrote:
           | Realistically, the vast majority of people will not have a
           | real chance to "refute" or even evaluate scientific claims.
           | Maybe given a lot of time and foundational work to learn the
           | field, some percentage of people can usefully think about
           | them, but the vast majority can't. A lot of people are
           | functional illiterates. They will pick based on trust and gut
           | feelings either way.
           | 
           | For example, when deciding whether to give your kids certain
           | vaccines or not, you really can't expect that new parents
           | will read the primary literature and try to refute or confirm
           | the conclusions based on the numbers and will trace through
           | the citations and so on... Any of those claims will also have
           | some online account on social media refuting it with equally
           | scientifically sounding words. In the end it will come down
           | to heuristics and your model of how the world works, which
           | set of people operate with what kind of intention. Like maybe
           | you know people working in the field who you trust and hear
           | from them that generally this sort of stuff can be trusted.
           | Or maybe you had some bad experiences getting screwed by "the
           | establishment" (maybe even unrelated to medicine) and now you
           | lump all this together and distrust them.
        
       | barbazoo wrote:
       | It always comes back to Goodhart's Law and our apparent inability
       | to create sustainable incentive structures.
        
       | butILoveLife wrote:
       | Industry >> Academia
       | 
       | Profits are the deciding factor, not honor.
        
       | jjk166 wrote:
       | More broadly, an incredible amount of our society's systems are
       | built around actors being uncoordinated. Redesigning institutions
       | to resist networks of coordinated action between seemingly
       | unlinked individuals will, in my opinion, be one of the great
       | social challenges of this era.
        
       | ukoki wrote:
       | If you get paid by the government to do research you should make
       | all your raw data, code, results etc, accessible to the public.
       | 
       | If it then turns out any of it is fabricated, you should be
       | personally liable for paying it back
        
       | canjobear wrote:
       | I ran into an interesting incident of this recently. I got a
       | Google Scholar alert about a paper with some experiments related
       | to a paper I had published a while ago, by one "N. Tvlg". I read
       | the paper with interest but I started noticing that although the
       | arguments sounded good, they didn't really make sense, and also
       | the descriptions of the results didn't really match the figures.
       | Eventually I came across a cluster of citations to completely
       | unrelated papers---my field is computational linguistics and
       | these were citations to, like, studies of battery technologies
       | for electric cars. I looked up "N Tvlg" on Google Scholar and
       | they had "published" several articles very recently in totally
       | divergent fields, and upon inspection, all of them had citations
       | back to this materials science research buried deeply somewhere.
       | Clearly these were LLM generated papers trying to build up
       | citation count and h-rank for someone's career.
        
         | reactordev wrote:
         | Where there's a ranking, there's someone out there trying to
         | cheat at it. Citation count is a joke.
        
         | matthewdgreen wrote:
         | The purpose of scientific publication used to be to deliver
         | useful scientific results to one's peers. This meant that
         | everyone ran their own personal filter of which peers were
         | working on interesting things, and which collections (journals)
         | were reproducing the most interesting ones. This system still
         | works relatively well for most conscientious researchers. The
         | idea that we should also use publication metrics to rank
         | researchers was never part of this system, and it obviously
         | leads to all sorts of spam (that most scientists just work
         | around) but that seems to really upset non-scientists.
        
       | fph wrote:
       | Are these "entities" named and shamed somewhere? I just scanned
       | the paper but couldn't find explicit mentions.
        
       | ventuss_ovo wrote:
       | This is the part that feels hardest to fix: once a system starts
       | rewarding throughput over scrutiny, fraud stops looking like
       | individual misconduct and starts looking like a supply chain
       | problem.
        
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