[HN Gopher] Influential study on glyphosate safety retracted 25 ...
       ___________________________________________________________________
        
       Influential study on glyphosate safety retracted 25 years after
       publication
        
       Author : isolli
       Score  : 228 points
       Date   : 2025-12-05 13:39 UTC (9 hours ago)
        
 (HTM) web link (www.lemonde.fr)
 (TXT) w3m dump (www.lemonde.fr)
        
       | jeffwask wrote:
       | Faking research data that then leads to the death of citizens
       | from your product should result in a corporate death sentence.
        
         | oftenwrong wrote:
         | The problem is always how well one can prove that any harm was
         | done, or that theoretical harm would be done.
        
         | readthenotes1 wrote:
         | and criminal penalty consequequences fornthe people who
         | prepared and signed the paper in bad faith
        
         | CGMthrowaway wrote:
         | What is a corporate death sentence? And if true, the list would
         | be LONG
        
           | isolli wrote:
           | Wiping out shareholders. I bet shareholders would be a lot
           | more cautious if that was an option.
        
           | u8vov8 wrote:
           | Ideally this:
           | 
           | https://en.wikipedia.org/wiki/2008_Chinese_milk_scandal
        
           | peppersghost93 wrote:
           | Dissolution of a company by revoking the charter and
           | liquidating all it's assets to anyone who will buy them.
        
         | dmix wrote:
         | It's not clear if the data is fake. Retraction Watch said it
         | was retracted because:
         | 
         | > authors didn't fully disclose their ties to Monsanto
         | 
         | and
         | 
         | > He also called out the authors' reliance on unpublished
         | studies from Monsanto for their conclusions that glyphosate
         | exposure did not cause cancer, though other studies existed.
        
         | zackmorris wrote:
         | A mechanism for harm could be that glyphosate disrupts the gut
         | lining barrier and flora, which can cause or contribute to
         | leaky gut, a loose term for digestive waste and foreign bodies
         | entering the bloodstream.
         | 
         | Those bodies can cause chronic inflammation and the strange
         | autoimmune disorders we see rising over time. Note that some
         | brands like Cheerios (which don't sell an organic equivalent)
         | can contain 700-800 ppb of glyphosate, well over the 160 ppb
         | limit recommend for children by the Environmental Working Group
         | (EWG).
         | 
         | US wheat and other crops seem to have become harder to digest
         | for some people due to genetic tampering. They contains
         | substances borrowed from other species to reduce pest damage,
         | which the body has little or no experience with, which may
         | trigger various reactions (this has not been studied enough to
         | be proven yet).
         | 
         | All of these effects from gut toxicity could lead to ailments
         | like obesity, malnourishment, cardiovascular disease, maybe
         | even cancer. This is why I worry that GLP-1 agonists may be
         | masking symptoms, rather than healing the underlying causes of
         | metabolic syndrome that have been increasing over time.
         | 
         | Many people have chosen to buy organic non-GMO wheat from other
         | countries for this reason. I believe this is partially why the
         | Trump administration imposed a 107% tariff on Italian wheat for
         | example, to protect US agribusiness.
         | 
         | Before you jump on me for this being a conspiracy theory, note
         | that I got these answers from AI and so will you.
         | 
         | My personal, anecdotal experience with this was living with
         | leaky gut symptoms for 5 years after a severe burnout in 2019
         | from (work) stress, which may have been triggered by food
         | poisoning. I also had extremely high cortisol which disrupted
         | everything else. So I got to the point where my meals were
         | reduced to stuff like green bananas, trying everything I could
         | to heal my gut but failing, until I finally snapped out of my
         | denial and sought medical attention.
         | 
         | For anyone reading this: if holistic approaches don't fix it
         | within say 6 weeks to 6 months, they aren't going to, and you
         | may need medication for a time to get your body out of
         | dysbiosis. But you can definitely recover and return to a
         | normal life like I did, by the grace of God the universe and
         | everything.
        
       | Havoc wrote:
       | Corporations will keep misbehaving until the consequences are
       | suitably sized to provide an incentive not to.
       | 
       | One of the reason I've been glad to see EU hand out chunkier
       | fines. Or at least attempt it...but there is remarkable
       | enthusiasm for defending billion dollar corporation's
       | misbehaviour because that would be over regulation
        
         | nathan_compton wrote:
         | When are we going to start imprisoning people, I wonder.
        
           | smt88 wrote:
           | It's bizarre that the right wing wants to execute people
           | convicted of a single murder, but tobacco and opioid execs,
           | responsible for millions of deaths, don't receive jail time
           | or even fines.
        
             | nielsbot wrote:
             | capitalism is our natural environment. like the air we
             | breathe. how can you punish it?
        
               | titzer wrote:
               | Can't you see the billionaires sprouting in the Spring?
               | Didn't you know they spread their delicate flowers just
               | like Jasmine has for millions of years?
               | 
               | /s
        
           | onli wrote:
           | Right. This is not an area of fines. This is a criminal
           | conspiracy with intent to kill on a wide scale. Absolutely
           | deserving of prison for everyone involved.
        
           | franktankbank wrote:
           | In this economy? We have people murdering CEOs for free!
        
             | antonvs wrote:
             | Are you saying Mangione should be tried for illegal dumping
             | of assassination services?
        
           | expedition32 wrote:
           | Yep. There was a company in my country that got a hefty bill
           | after they contaminated a river for a few decades. They
           | simply decided to go bankrupt and leave the country.
           | 
           | Apparently corporations can spin up subsidiaries that are
           | legally siloed.
        
           | frmersdog wrote:
           | When the alternative is regular and predictable violence. The
           | corporate elite who don't cause issues will vouch for a
           | stronger rule of law wrt their actions, out of fear of
           | becoming an undeserving victim of the zeitgeist. It's better
           | to get dragged into court and be able to prove that you
           | didn't do anything wrong (or even to actually face that
           | prison term), than to get dragged into the street and not see
           | the next sunrise.
           | 
           | I do think that Thompson and Kirk are finally opening some
           | eyes to the possibilities, on both sides.
        
           | hermitcrab wrote:
           | When their employers stop giving freebies to politicians?
        
           | 11101010001100 wrote:
           | Pay the fine and Pay for pardon is the business du jour.
        
         | SamaraMichi wrote:
         | Considering the cogs at corporations are going above and beyond
         | to cover for their wrongdoings despite our perceived lack of
         | consequences is concerning, it would seem their efforts to hide
         | their actions would only balloon.
        
       | delichon wrote:
       | I can feel the pull of glyphosate. I want to kill the weeds right
       | around my house, but that's where my dog sleeps and rolls and
       | eats the grass. Roundup is the popular weed killer and I've got a
       | bottle in the garage. So I look up its effects on pets, and it
       | says "manageable with precautions", particularly waiting for the
       | fluid to dry before letting the dog on it.
       | 
       | I'm not very comfortable with that so looking around for other
       | solutions I see a guy on Youtube telling me how to manage weeds
       | with vinegar. I figure that must be safe, so I buy a bottle of
       | the recommended concentration, but for the hell of it look up its
       | safety for dogs before applying it. They say hell no, this is way
       | too strong for pets and can cause burns, etc. I would need to
       | dilute it quite a bit, making it a lot less effective.
       | 
       | So I ended up using glyphosate, but I'm looking for something
       | better.
        
         | moab wrote:
         | How about not killing the weeds? One doesn't need to live a
         | perfectly manicured pesticide-ridden hellscape.
        
           | GaryBluto wrote:
           | How about letting him do what he wants with his own land and
           | not insulting his ideal home?
        
             | snapdeficit wrote:
             | How about thinking about society and not just every man for
             | himself? Clearly you didn't read TFA.
        
               | morkalork wrote:
               | No, this is HN where we voraciously advocate for the
               | libertarian ideals of "I do what I want" then pontificate
               | about the tragedy of the commons from an ivory tower when
               | it inevitably all goes wrong.
        
             | moab wrote:
             | You're entitled to your own opinion, but imo the point of
             | posting anything on HN is to subject yourself to feedback.
             | That's what I gave. Feedback.
        
             | striking wrote:
             | Their comment asked for an alternative.
        
               | GaryBluto wrote:
               | He wanted an alternative method to achieve X, not abandon
               | X and do Y.
        
             | oftenwrong wrote:
             | What if I want to do something on my land that will poison
             | the ground water for the area? What if I want to raise an
             | invasive species on my land that will likely escape and
             | devastate local wildlife? Should society be permissive and
             | wait for the damage to be done before stopping me, instead
             | of being proactive and stopping me from doing so before the
             | fact?
        
               | GaryBluto wrote:
               | Last time I checked that wasn't what he was planning on
               | doing.
        
               | nullstyle wrote:
               | Last time i checked you were giving out blank checks. We
               | live in a society
        
               | filoeleven wrote:
               | That is literally what he is doing. None of your lawn
               | grass is native.
        
           | delichon wrote:
           | I live in an extremely high wildfire risk area. I also have
           | an extreme rodent problem. Keeping the vegetation low around
           | structures is indicated.
        
             | triceratops wrote:
             | Keeping vegetation low is a different problem from removing
             | weeds in a targeted fashion. A simple mower or trimmer
             | should suffice.
        
             | moab wrote:
             | You can do that by mowing, fyi.
        
               | Zach_the_Lizard wrote:
               | Can't do that in cracks in a sidewalk, between pavers, on
               | a wall, etc. where plant growth can damage them.
        
               | komali2 wrote:
               | Weed whacker and edger? You'll have them out anyway.
        
               | delichon wrote:
               | I weed whack acres, it is a huge sink of my free time.
               | But there are areas where I don't want to mow, I want to
               | eliminate growth, like on my gravel driveway, and the
               | area adjacent to my house. I should probably install
               | concrete instead of gravel, but that's telling myself to
               | just eat cake since I have no bread.
        
           | Zach_the_Lizard wrote:
           | Some weeds are quite unpleasant, such as sticker burrs. I'd
           | rather not have a dog and children covered in those.
           | 
           | Some weeds can be damaging to property, trees, sidewalks,
           | etc. or are poisonous.
           | 
           | It's not always about being annoyed by dandelions in an
           | otherwise overly fussed over sterile lawn environment.
        
             | onli wrote:
             | Even then, spraying cancer causing chemicals into the land
             | is beyond stupid. Killing yourself and the humans around
             | your land for having a bit less work, one can't be more
             | antisocial.
        
           | derriz wrote:
           | Or if you do want a manicured plot, just cut them with a
           | lawnmower?
           | 
           | The bane of my young life was having the job of cutting the
           | grass around the house - we lived in the country at the time
           | and had about 1/2 an acre of lawn as well as fruit trees,
           | plants, vegetables, etc.
           | 
           | We never considered using weedkiller - I just can't see the
           | need. Isn't it just as easy to pull the weed out of the
           | ground as it is to spray round-up on it and wait for it to
           | die, before presumably anyway pulling the remains of it?
           | 
           | Ignoring the health implications completely, I can see some
           | "value" of using round-up in a commercial environment where
           | your dealing with 100s of acres or more but fail to see what
           | benefit it provides in a domestic setting when the number of
           | weeds is small enough that it would just takes minutes to
           | remove them physically and toss them into a compost heap.
        
             | Retric wrote:
             | I rarely use weed killer on poison ivy to avoid coming into
             | physical contact. Lawnmowers work fine for flat yards, but
             | for steps down a steep embankment you really need a weed
             | eater and weed eater + poison ivy is a major hassle.
        
             | mrgoldenbrown wrote:
             | Digging weeds and their roots up one by one by hand out of
             | cracks in concrete/asphalt is much slower than spraying.
             | Also much more physically challenging, which is a metric I
             | didn't care about when young and able bodies but nowadays
             | is very relevant to me. I'm not saying roundup is good, but
             | there are plenty of reasons for it to be appealing. I
             | haven't tried the boiling water method yet, it seems like
             | it'd be easier than digging but harder than spraying,
             | unless perhaps one has a mobile, outdoor source of boiling
             | water.
        
               | reeredfdfdf wrote:
               | What is the point of removing weeds from those cracks in
               | the first place? Do they cause some kind of physical harm
               | to creatures or objects that move on that concrete or
               | asphalt surface?
        
               | hexaga wrote:
               | The concrete itself can be damaged further over time by
               | expanding root networks / growth.
        
           | analog31 wrote:
           | In my area, some weeds will absolutely take over and choke
           | out everything else while also spreading throughout the
           | neighborhood to the delight of all.
           | 
           | But roundup isnt much of an option when the weeds are next to
           | the nice stuff. My compromise is to pull the weeds when I'm
           | motivated to and call it a day.
        
             | TitaRusell wrote:
             | This is how humans had to do it for millennia- by hand.
             | Backbreaking work. But necessary unless you wanted to lose
             | half the harvest.
             | 
             | I dislike gardening and enjoy my apartment!
        
           | malfist wrote:
           | Pesticides aren't used to kill weeds.
           | 
           | Herbicides are useful, they certainly help prevent invasive
           | weed species from taking over native plants and grasses. I'm
           | Kentucky I'm always fighting Johnson grass, thistle and
           | Japanese knotweed in my bluegrass
        
             | Angostura wrote:
             | Pesticide is a catch-all term that encompasses herbicides,
             | insecticides, fungicides etc.
        
               | malfist wrote:
               | No, it isn't. Pesticide are used to kill pests, such as
               | insects in the case of insecticide or rodents. It does
               | not include fungicides nor herbicides
        
               | dragonwriter wrote:
               | > Pesticide are used to kill pests, such as insects in
               | the case of insecticide or rodents. It does not include
               | fungicides nor herbicides
               | 
               | Wrong.
               | 
               | See, e.g., https://www.fda.gov/food/chemical-
               | contaminants-pesticides/pe...
               | 
               | "Pesticides are used in agriculture to protect crops from
               | insects, fungi, weeds, and other pests."
        
           | psunavy03 wrote:
           | Why is something someone else enjoys a "pesticide-ridden
           | hellscape?"
           | 
           | How would you like me to come and pompously shit all over
           | something you enjoy?
        
           | jhide wrote:
           | I agree about with your claim, but the answer to your
           | question is that "weeds" is a set of species that contains
           | both invasive, ecologically harmful species, and crucial
           | native annual and perennial forbs+grasses.
           | 
           | From the universalizability principle, if everyone merely let
           | "weeds" propagate, because of the ecology of invasives that
           | are in that set, we would be MUCH worse off for the next few
           | millennia than we are now. Until the ecosystems healed and
           | the "invasives" become "keystone species". Not sure how long
           | that would take but we won't see it :)
        
           | hermitcrab wrote:
           | We don't mow one part of our lawn and have sowed it with
           | wildflowers) which some people might call weeds) to attract
           | insects. Some wildflowers prefer poor soil, so my wife
           | scythes it at the end of the season and removes all the
           | cuttings. I'm hoping we might get some native orchids
           | eventually.
        
           | mvdtnz wrote:
           | Sorry you think my Japanese garden is a hellscape.
        
         | hammock wrote:
         | You sound neurotic. Anyway just pull the weeds out with a towel
         | and you hands, or use boiling water to kill them
        
           | Zach_the_Lizard wrote:
           | Pulling weeds by hand works for a lot of weeds and is the
           | most environmentally friendly solution where possible. It's
           | what I've done, for the most part.
           | 
           | I will say for some weed species that can be ineffective or
           | counterproductive, unfortunately, and for those a chemical
           | (or other) solution may be in order.
           | 
           | Weeds can also be a sign of a potential problem, such as poor
           | drainage, a leak, etc.
           | 
           | Nutsedge is an example of that. As I recall, pulling it out
           | results in it sending more shoots up if you don't get the nut
           | (which can be feet underground).
           | 
           | At that point, you have to continuously pull weeds on a daily
           | (or multiple times daily) basis in order for it to use up
           | more energy growing than it generates.
           | 
           | It likes water, so if it's there, it might be because there's
           | standing water from rain.
           | 
           | I dug up a raised flower bed to get rid of it once. Nuts were
           | absolutely everywhere because of poor drainage. I had to go
           | down 2 feet I think to get them all, I replaced the bottom
           | layers of impermeable clay soil with something that drained,
           | along with a drain pipe or two.
           | 
           | Now the sedge is gone, the risk of foundation damage from
           | being too wet is gone, and no chemicals were required.
        
         | zzzeek wrote:
         | you had to choose between vinegar and glyphosate, I'd use the
         | vinegar. your dogs aren't going to roll around in a too-strong
         | concentration of vinegar, it has a smell and if it were
         | actually going to cause burns (what kind of vinegar is this,
         | something from a chemical supply house? ) animals would be
         | immediately repelled by it (plus it evaporates quickly anyway).
         | whereas with glyphosate, none of that applies, it's a fully
         | synthetic chemical that stays in the atmosphere for _days_ ,
         | would not send any cues to animals, and its effects on animals
         | may be long term, concealed for years, and fatal.
         | 
         | but as someone else said above, if this is a certain area that
         | your dog wants to be, you can always pull weeds for that area
         | by hand, just make sure you get the entire root.
        
           | delichon wrote:
           | Thanks for the advice. I bought 30% vinegar on Amazon. The
           | instructions are to add in a little dish soap. Do you think
           | that will safely repel the dog when dry?
        
             | quesera wrote:
             | The soap is a surfactant to make the vinegar stick to the
             | weed leaves for longer.
             | 
             | It's not necessary, but it probably lets you use a little
             | less vinegar, so it's probably worthwhile. I don't add
             | soap, I just spray straight 30% (agricultural) vinegar in
             | the small set of areas where a torch would be dangerous.
             | 
             | Dried vinegar does not irritate dogs. They will avoid the
             | area while it smells like pickles.
             | 
             | A better chemist than I will hopefully corroborate this,
             | but I think that the strength of smell is directly
             | correlated to the reactivity of the acid. So when the smell
             | is mild (i.e. near the level of household vinegar (5%)),
             | the risk to skin and mucous membranes is low-to-zero.
        
             | kergonath wrote:
             | I don't think there will be much left of the vinegar when
             | dried. Acetic acid is much more volatile than water. If
             | it's dry, it means that it's gone. And it has an unpleasant
             | smell even at harmless concentrations, if it's not quite
             | dry yet.
        
         | lqet wrote:
         | Weeds on the lawn: just use a lawnmower each week, the grass
         | will usually handle being cut on a weekly basis _much_ better
         | than any weed.
         | 
         | Weeds between tiles / slabs or on gravel: just pour boiling
         | water over them. The weeds will become mushy and die within 1-2
         | days. Repeat every 6 weeks during summer.
         | 
         | Source: we bought a house with a garden full of goutweed [0],
         | which I consider the final boss of any garden owner, and which
         | we have in control now through regular mowing / hot water.
         | Goutweed will just laugh at any herbicide you throw at it, and
         | regrow from its underground rhizomes. I also doesn't seem to
         | require sun, because I have seen plants grow to a height of
         | 10cm _completely underground_. The joke in my family is that it
         | could grow on foreign planets. As Wikipedia dryly puts it:
         | "Once established, goutweed is difficult to eradicate."
         | 
         | [0] https://en.wikipedia.org/wiki/Aegopodium_podagraria
        
           | dwroberts wrote:
           | This is just a recipe to spread weeds everywhere. If you mow
           | them, most of the time you'll just break them open and spread
           | their seeds
        
             | n4r9 wrote:
             | But if you then keep mowing the lawn regularly, those seeds
             | won't be able to compete with the grass.
        
               | lupire wrote:
               | Why wouldn't they be able to compete?
        
               | amanaplanacanal wrote:
               | Usually seeds need soil contact and sunshine to germinate
               | and grow. Thick lawn can mitigate that.
        
               | hermitcrab wrote:
               | IIRC grass grows from the bottom, which means it is very
               | resistant to being mowed or grazed. Weeds/wildflowers not
               | so much.
        
               | DeepSeaTortoise wrote:
               | Unless you mow your grass too low. Always assume the old
               | rule of "your grass reaches just as far underground as it
               | reaches up in the air" still holds.
               | 
               | Also if you mow your grass drastically shorter or you let
               | it grow for a long time before mowing, do not fail to
               | fertilize it from above right or soon after, start
               | aggressively plucking the leaves of weeds (or other
               | selective methods of fighting them) for a few weeks and
               | (optimally, but highly recommended) verticulate it no
               | sooner than 1 week after cutting. Also time it well to
               | grant your lawn at least 3 weeks of ideal growing weather
               | and climate (It won't die because of a week or two of
               | awful weather, but you'll have A LOT more work fighting
               | weeds ahead of yourself).
        
             | lqet wrote:
             | I you mow them after they have developed seeds, you are
             | mowing them too late.
        
             | mvdtnz wrote:
             | Or you can learn the lifecycle of plants and don't let them
             | go to seed.
        
           | lupire wrote:
           | I don't understand. What we call "weeds" are plants that
           | evolved to grow quickly and spread quickly. Many gave
           | segmented stems/leaves to resist core damage from cuts and
           | pulls.
        
           | DeepSeaTortoise wrote:
           | You can also use just heat. Like a long propane torch or one
           | of the newer electric infrared ones. It doesn't need a lot of
           | heat, a short burn (like a bit less than a second) is
           | perfectly sufficient to make them wilt within a few days.
           | 
           | Weeds are the flora equivalent of VC-hype-startups. All
           | growth, no substance and no plan B. They pop-up everywhere,
           | with seemingly infinite growth resources and hope you'll
           | despair and do nothing.
           | 
           | Just going around plucking leaves from everything that looks
           | like you won't like it for a few weeks twice a year works
           | wonders.
           | 
           | Basically regulatory capture for your lawn. No need to help
           | along your darlings (in the beginning), just make everyone
           | else play with stupid rules. And once things start going down
           | the drain, it's time for subsidies (fertilizer) and public
           | contracts (pre-germination).
        
             | pengaru wrote:
             | Thank you for making my morning coffee, consumed while
             | looking down on downtown San Francisco, presently chock
             | full of "AI" weeds, substantially more entertaining.
        
             | SoftTalker wrote:
             | Never had much luck with burning or cutting weeds from the
             | top. They just resprout and grow back. Haven't tried
             | boiling water.
             | 
             | I just use roundup, honestly. It works.
        
           | BigTTYGothGF wrote:
           | I will hate the ground elder as long as I live (but did
           | manage to eradicate it from our garden thru hard work, only
           | to see it spring back up in our neighbor's yard, it's their
           | problem (for) now).
        
         | whalesalad wrote:
         | absolutely insane that you held glyphosate and vinegar in two
         | hands and decided to opt for glyphosate. vinegar will not hurt
         | your dogs. use vinegar, or fire, or drench the weeds in water
         | and pull them out by hand.
        
           | starkparker wrote:
           | If it's low-concentration or diluted vinegar, then yes, but
           | more for maintenance than to kill established weeds.
           | 
           | But industrial-strength vinegar is corrosive and harmful on
           | skin, eye, and lung contact. If OP looked at the bottle and
           | saw skin irritant or corrosion warnings required to be
           | present on it (in the US, at 8% or higher acetic acid
           | concentrations; in the EU, I think it's skin irritant 10-25%,
           | corrosion 25%+), then it's probably that.
           | 
           | Garden stores often sell 20%-45% concentration vinegars, and
           | YouTube/TikTok influencers often promote industrial-strength
           | vinegar at 75% concentrations, at which point it'll damage
           | turf on contact. And any repeat or large pour of high-
           | concentration vinegar can reduce the soil pH deeper than
           | expected, which can be harmful to nearby trees or other root-
           | system plants.
        
         | oldandboring wrote:
         | As I'm sure you're aware, glyphosate is usually only
         | appropriate as a weed killer on your property if you're looking
         | to kill all vegetation in/around where you spray it. For
         | example if you wanted to "nuke" your lawn by killing all the
         | grass and starting over with new grass. It's a non-selective
         | herbicide in this context, it kills everything.
         | 
         | If you've got some dandelions or thistle, and it's not out of
         | control, the nice safe way is to pull them up by hand or, if
         | they're between pavement cracks, pour boiling water on them.
         | 
         | Broadleaf weeds growing in your lawn that aren't easily hand-
         | pulled can be killed with a selective herbicide like 2,4-d.
         | Tough underground vine-style weeds like creeping charlie or
         | wild violet will need a selective called triclopyr. Crabgrass
         | is best killed by a selective called quinclorac. Yellow
         | nutsedge requires a selective called sulfrentrazone or another
         | called halosulfuron.
         | 
         | Selectively kill the weed infestations as best you can, get rid
         | of the bad ones before they go to seed, and focus on the health
         | of your grass -- in most parts of your lawn, healthy grass will
         | out-compete weeds.
        
           | DeepSeaTortoise wrote:
           | Don't spray herbicides everywhere (unless you're certain
           | that's what you want or need).
           | 
           | Instead, just spray each weed a little bit, right above where
           | the leaves connect to the stem.
        
           | itsdrewmiller wrote:
           | I get a little paintbrush and paint the leaves of each
           | dandelion with round-up - that ends up killing them but
           | largely leaving other plants alone.
        
             | ok_computer wrote:
             | How is this easier than pulling the plant out of the soil?
        
               | jhide wrote:
               | It depends on the target and the surrounding soil. It's
               | often easier to pull especially for the random weed that
               | sprouts up around your landscaping. However if you are
               | trying to manage an infestation of invasive species,
               | where the surrounding soil will have a seed bank heavily
               | contaminated with seeds from the years of invasive
               | reproduction, it's usually a bad idea to merely pull. You
               | can expose soil to sunlight and cause an explosion of
               | dormant seeds. And some nasty invasives are nearly
               | impossible to remove by hand because of their root
               | structure -- some species even leave little rhizomes
               | broken off in the soil along the root structure when you
               | pull off the foliage causing a hydra effect.
               | 
               | tl;dr targeted herbicide is a much less evolutionarily
               | selected-for offense, as opposed to hand cultivation
               | which mimics attacks plants have evolved to survive for
               | eons
        
               | jfengel wrote:
               | Dandelions are really, really hard to eradicate by
               | pulling. The roots grow very deep, and if you don't get
               | them completely, the plant can re-grow from what's left.
               | 
               | Even if you do successfully get it out, it really is
               | going to be more work than painting a weed killer on
               | them.
        
               | SoftTalker wrote:
               | My dad use to have my brother and I work for hours during
               | the summer pulling dandelions in the lawn (to be fair he
               | was out there with us doing it himself also). We each had
               | a knife with about a 4" long blade, we would cut the root
               | as deep as we could and pull the top out. Never really
               | seemed to reduce the number we had.
        
             | detritus wrote:
             | I did much the same, but with a hypodermic syringe, on
             | knotweed many years ago.
             | 
             | Yours is so much more.. tender though. Poor dandelions, but
             | at least you made it personal!
        
             | BigTTYGothGF wrote:
             | I learned to appreciate the dandelions.
        
           | mvdtnz wrote:
           | Glyphosate is extremely effective as a targeted weed killer.
           | It only impact what you spray it with. It does not teleport
           | from one plant to another. It's also not strong enough to
           | kill heathy mature plants with a small amount of overspray.
        
           | mapontosevenths wrote:
           | When I really want to nuke it so that nothing grows, like in
           | a decorative stone area, I use water softener salt. I
           | dissolve it in a bucket of water until no more will dissolve
           | then pour it wherever I want the vegetation to stop growing.
           | 
           | Anything there will die, and nothing will grow again for a
           | long time. Although, it does spring back to life eventually.
           | Usually once a year is sufficient.
        
         | mapt wrote:
         | Depending on weather and the site, a weed burner can be very
         | effective for what people used to use glyphosate for.
         | 
         | For large areas, tarping can work pretty well in the summer. I
         | accidentally cut a perfectly rectangular hole in my lawn by
         | leaving a tarp on the ground as I was moving soil into
         | containers. Enough sunlight was absorbed through the
         | translucent plastic that it quickly baked the area underneath
         | to death.
        
         | gnv_salsa wrote:
         | Unless you have an old Roundup bottle, you don't have
         | glyphosate in it. From the Bayer website:
         | 
         | "The active ingredients found in our Roundup Lawn & Garden
         | products in the U.S. are: fluazifop-p-butyl, triclopyr TEA
         | salt, diquat dibromide and imazapic ammonium. These ingredients
         | have been used safely and effectively in many different weed-
         | control products from a variety of companies for decades."
         | 
         | "We have been very transparent about the new formulation of
         | Roundup Lawn & Garden products and are no longer producing
         | glyphosate-based Roundup products for the U.S. residential lawn
         | and garden market. While Bayer no longer produces or sells
         | glyphosate-based Roundup products - which are also EPA-approved
         | - some quantities may remain on store shelves until remaining
         | stocks are sold. "
        
           | rithdmc wrote:
           | This is cool, & new to me. Do you know when they made the
           | change? "some quantities may remain on store shelves until
           | remaining stocks are sold" implies it was recently to the
           | post, but I'm not sure when that was.
        
             | pixl97 wrote:
             | 2023, so yea, there may still be some older product around.
        
           | oatmealcookie wrote:
           | I wonder if that includes Roundup Pro, because they still
           | have it as being glyphosate on their website:
           | 
           | https://www.rounduppro.com/products/roundup-promax-
           | herbicide...
        
           | qwerpy wrote:
           | I had a tree root growing through the driveway asphalt. My
           | handyman told me to get Roundup Pro because it will actually
           | kill the root, unlike the other herbicides. So I got a
           | gigantic gallon tub of it. It was effective. Good to know
           | that "the good stuff" is now found to be not problematic.
        
           | BigGreenJorts wrote:
           | In Canada while the majority is vinegar now, I still see
           | glyphosate roundup products.
        
         | troyvit wrote:
         | If it's dandelions, wait a few seasons (now that you've used
         | Roundup) and then eat them! The leaves taste like arugula (the
         | younger the better). The heads, when they bloom, can be dried,
         | ground, and baked into cookie recipes. If you let the heads
         | close, pick them before they start transforming into seeds and
         | either pop them into your mouth raw while you're doing yard
         | work or save them, bread them, and fry them up for a nutty
         | flavor. The roots apparently make a good caffeine-free coffee
         | replacement but who the hell wants to _replace_ coffee?
        
         | BigTTYGothGF wrote:
         | > I would need to dilute it quite a bit, making it a lot less
         | effective.
         | 
         | Doesn't the vinegar act pretty quickly? Keep the dog inside
         | that afternoon, then hose it down in the morning.
        
         | mvdtnz wrote:
         | Glyphosate is perfectly safe at the levels we use it
         | domestically. If there is a safety issue it's at commercial
         | dosages.
        
         | NoGravitas wrote:
         | A garden torch is unreasonably effective.
        
           | bluGill wrote:
           | Terrible for the environment though what with all the co2.
        
         | DANmode wrote:
         | Places with common sense regarding human health do weed control
         | with a small torch.
        
         | vinibrito wrote:
         | Salt for cattle.
         | 
         | Lasts for a few months.
        
         | rsync wrote:
         | "So I ended up using glyphosate, but I'm looking for something
         | better."
         | 
         | Not for everyone and not for every situation, but ...
         | 
         | If you get a propane torch - the full sized ones that attach to
         | a 5gal. propane tank - you can very quickly point-and-shoot a
         | large area with similar effort expended to walking around
         | spraying a liquid.
         | 
         | We have a 2500sf veranda made of decomposed granite and it
         | takes about four man-hours to fully clear it of all creepers
         | and flat broadleafs and all the other things that are
         | impossible to pull by hand ... and since it kills them you're
         | clear for the season ...
        
       | rybosworld wrote:
       | The sole surviving researcher attached to that paper is still
       | actively publishing:
       | 
       | https://www.sciencedirect.com/author/24433485700/gary-m-will...
        
       | samlinnfer wrote:
       | So what's the current speculation on how it causes cancer?
       | 
       | Glyphosate acts on the Shikimate pathway that doesn't exist in
       | humans.
       | 
       | Is it killing gut bacteria?
        
         | hammock wrote:
         | Mechanistic evidence shows low doses cause genotoxicity and
         | oxidative stress in human lymphocytes and other cells.
         | 
         | A novel mechanism proposal is that glyphosate may chelate and
         | accumulate in the bone, slowly releasing into the bloodstream,
         | exposing bone marrow and potentially triggering hematologic
         | malignancies.
         | 
         | https://www.sciencedirect.com/science/article/abs/pii/S21522...
        
         | pfdietz wrote:
         | My theory is that if you torture a chemical with enough diverse
         | studies, you can find some where it confesses to causing
         | cancer, even if it actually doesn't.
        
           | smt88 wrote:
           | If what you say is true, we would know almost nothing about
           | pharmacology and modern medicine wouldn't exist.
           | 
           | There are basic scientific and statistical methods to avoid
           | this.
        
             | pfdietz wrote:
             | There are, but there are also strong incentives for what
             | amounts to fraud, on both sides. Glyphosate has become both
             | highly politicized -- it's used as an argument against GMOs
             | -- and subject to concerted and lucrative legal attack. At
             | the same time, the patent is expired, so the motivation to
             | continue to defend it has waned. If anything, herbicide
             | producers would now benefit if a cheap, public domain
             | chemical were illegitimately banned in favor of more
             | expensive chemicals still under patent protection.
             | 
             | Even when supposedly honest scientists publish, it's often
             | wrong.
             | 
             | https://en.wikipedia.org/wiki/Why_Most_Published_Research_F
             | i...
        
               | earlyreturns wrote:
               | This was and probably still is true about tobacco.
               | Personally, I choose to not smoke.
        
               | pfdietz wrote:
               | The evidence against tobacco was overwhelming.
        
               | cbolton wrote:
               | > the patent is expired, so the motivation to continue to
               | defend it has waned. If anything, herbicide producers
               | would now benefit if a cheap, public domain chemical were
               | illegitimately banned in favor of more expensive
               | chemicals still under patent protection
               | 
               | That doesn't square with the fact that Monsanto thought
               | it worthwhile to commit scientific fraud to push the
               | narrative that glyphosate is safe, in a scientific paper
               | published the same year that the patent expired.
        
               | pfdietz wrote:
               | They had patents on Roundup Ready seeds. Those patents
               | have also now expired.
        
           | hombre_fatal wrote:
           | When it comes to mechanistic speculation, absolutely.
        
         | NotGMan wrote:
         | Human gut bacteria have the Shikimate pathways so it can kill
         | them.
         | 
         | Basicaly glyphosate could act like a gut bacteria antibiotic.
         | 
         | >> 54% of the human core gut bacterial species are potentially
         | sensitive to glyphosate, which targets an enzyme in the
         | shikimate pathway, suggesting that roughly half of gut bacteria
         | possess this pathway
         | 
         | https://www.sciencedaily.com/releases/2020/11/201120095858.h...
        
       | striking wrote:
       | https://archive.is/dRAMg
        
       | pella wrote:
       | https://retractionwatch.com/2025/12/04/glyphosate-safety-art...
       | 
       |  _" """Their request "was actually the first time a complaint
       | came to my desk directly," Martin van den Berg, a co-editor-in-
       | chief of the journal, told Retraction Watch. The article was
       | published long before he took over, said van den Berg, a
       | toxicologist at the University of Utrecht in the Netherlands, and
       | "it was simply not brought to my attention" until Kaurov and
       | Oreskes' article. The retraction "could have been done as early
       | as 2017, but it is clearly a case of two parallel information
       | streams not connecting earlier," he said.""""_
        
       | Zigurd wrote:
       | The longest thread on this topic is currently about household use
       | of glyphosate as weed killer. As many have pointed out that's
       | unnecessary. There are plenty of ways of killing weeds without
       | glyphosate.
       | 
       | It's also not a huge problem in the way that industrial use of
       | chemicals, like lead in gasoline, are a mass-poisoning event.
       | Glyphosate is used to desiccate wheat to make it easier to
       | harvest. That's where the big problems could come from.
        
         | masfuerte wrote:
         | Oats too.
        
         | xhkkffbf wrote:
         | Not just wheat. Other crops. I was pretty shocked to see a
         | field full of soybeans that were all dead. They were being
         | dried before harvest.
         | 
         | Terrible scheme.
        
           | bluGill wrote:
           | I've never heardof a farmer spraying soybeans for that
           | reason, and I know a fair number of soybean famers. The
           | plants naturally die at the end of the year, and farmers then
           | wait a few weeks for them to dry
        
         | fransje26 wrote:
         | > Glyphosate is used to desiccate wheat to make it easier to
         | harvest.
         | 
         | Wheat, soy, lentils, ...
        
       | zug_zug wrote:
       | Tl; dr:
       | 
       | One of the cornerstone studies claiming glyphosate was safe is
       | now suspected to have been written entirely ghost-written by
       | Monsanto.
       | 
       | A recent analysis (2025) shows that this paper has been cited
       | more than 99.9% of all glyphosate-related research -- i.e. it
       | disproportionately shaped scientific and public perceptions of
       | glyphosate's safety for decades.
       | 
       | [ https://undark.org/2025/08/15/opinion-ghostwritten-paper-gly...
       | ]
        
       | mhitza wrote:
       | Veritasium has a couple months old video that talks about this
       | issue, and other various issues around agriculture area (Monsanto
       | "seed mafia") in this video
       | https://www.youtube.com/watch?v=CxVXvFOPIyQ
        
       | jl6 wrote:
       | > The disavowal comes 25 years after publication and eight years
       | after thousands of internal Monsanto documents were made public
       | during US court proceedings (the "Monsanto Papers"), revealing
       | that the actual authors of the article were not the listed
       | scientists - Gary M. Williams (New York Medical College), Robert
       | Kroes (Ritox, Utrecht University, Netherlands), and Ian C. Munro
       | (Intertek Cantox, Canada) - but rather Monsanto employees.
       | 
       | Why wasn't the paper retracted 8 years ago?
        
         | readthenotes1 wrote:
         | It's hard to admit we're wrong
        
         | CGMthrowaway wrote:
         | Trust the science. The World Health Organization on glyphosate
         | in 2016:                 "The only large cohort study of high
         | quality found no evidence of an association at any exposure
         | level"       "Glyphosate is unlikely to be genotoxic at
         | anticipated dietary exposures"       "Glyphosate is unlikely to
         | pose a carcinogenic risk to humans from exposure through the
         | diet"       "The Meeting concluded that it was not necessary to
         | establish an ARfD for glyphosate or its metabolites in view of
         | its low acute toxicity"
         | 
         | https://www.fao.org/fileadmin/templates/agphome/documents/Pe...
         | 
         | Tptacek in 2018:                 "There are no credible studies
         | indicating that glyphosate is a carcinogen, and it would be a
         | little bit surprising it if was, since it targets a metabolic
         | pathway not present in animals. Meanwhile, many of the
         | herbicides that glyphosate displace, plenty of which remain in
         | use, are known human carcinogens. The most widely reported
         | declaration of glyphosate's carcinogenicity, by IARC, was
         | disavowed by the WHO, IARC's parent organization...The evidence
         | seems to suggest that glyphosate is basically inert in humans"
         | 
         | https://news.ycombinator.com/item?id=17043887
         | 
         | When Dr. Oz in 2015 spoke out against glyphosate, ten prominent
         | physicians wrote a letter to Columbia University in demanding
         | his removal from the faculty for an "egregious lack of
         | integrity" and for his "disdain for science and for evidence-
         | based medicine." He replied "I bring the public information
         | that will help them on their path to be their best selves" and
         | provides "multiple points of view, including mine, which is
         | offered without conflict of interest."
         | 
         | https://www.agrimarketing.com/ss.php?id=95305
         | 
         | Here is Reuters with a 3000-word Special Inverstigative Report
         | filed under "Glyphosate Battle" carrying water for Monsanto,
         | after IARC declared the chemical 2A (probably carcinogenic):
         | 
         | https://www.reuters.com/investigates/special-report/who-iarc...
        
           | hombre_fatal wrote:
           | Big Dr Oz fan eh? Got any quotes from Oprah or other HNers to
           | balance the epistemic master class?
        
             | superxpro12 wrote:
             | even a broken clock can be right every now and then
        
               | dctoedt wrote:
               | > _even a broken clock can be right every now and then_
               | 
               | But a broken clock isn't a _reliable_ indicator of time:
               | You don 't know when it's right unless you have another,
               | known-good indicator -- in which case just use that other
               | one.
        
             | CGMthrowaway wrote:
             | No the opposite. I trust Monsanto, they know this chemical
             | better than anyone.
        
               | davidw wrote:
               | I wouldn't really trust either one. Plenty of big
               | companies have known how horrible their own products are,
               | like cigarette companies, or fossil fuels. We'll probably
               | learn about social media companies in a few years.
               | 
               | That said, just because a product comes from a big
               | company doesn't mean it's bad either. I want to see
               | independent research.
        
               | isolli wrote:
               | We already know about social media companies (allegedly,
               | at least):
               | 
               | > Meta buried 'causal' evidence of social media harm, US
               | court filings allege [0]
               | 
               | > In a 2020 research project code-named "Project
               | Mercury," Meta scientists worked with survey firm Nielsen
               | to gauge the effect of "deactivating" Facebook, according
               | to Meta documents obtained via discovery. To the
               | company's disappointment, "people who stopped using
               | Facebook for a week reported lower feelings of
               | depression, anxiety, loneliness and social comparison,"
               | internal documents said.
               | 
               | > Rather than publishing those findings or pursuing
               | additional research, the filing states, Meta called off
               | further work and internally declared that the negative
               | study findings were tainted by the "existing media
               | narrative" around the company.
               | 
               | > Privately, however, a staffer insisted that the
               | conclusions of the research were valid, according to the
               | filing. "The Nielsen study does show causal impact on
               | social comparison," (unhappy face emoji), an unnamed
               | staff researcher allegedly wrote. Another staffer worried
               | that keeping quiet about negative findings would be akin
               | to the tobacco industry "doing research and knowing cigs
               | were bad and then keeping that info to themselves."
               | 
               | [0] https://www.reuters.com/sustainability/boards-policy-
               | regulat...
               | 
               | Edit: it was discussed here a few days ago [1]
               | 
               | [1] https://news.ycombinator.com/item?id=46019817
        
               | 0cf8612b2e1e wrote:
               | Got any hot tips from Marlboro I should read as well?
        
               | mistrial9 wrote:
               | Thank You for Smoking !
        
               | jibal wrote:
               | Great movie, opened the Santa Barbara International Film
               | Festival years back.
        
               | cbolton wrote:
               | Is this sarcasm or are you seriously saying you trust
               | Monsanto on a thread about them committing scientific
               | fraud to influence our perception of their product?
        
               | tsimionescu wrote:
               | Sarcasm, given the previous comments.
        
           | xenophonf wrote:
           | CGMthrowaway writes:
           | 
           | > _Trust the science._
           | 
           | Science is a process, not a result. Retractions like this
           | promote the integrity of scientific research and evidence-
           | based medicine.
           | 
           | > _When Dr. Oz in 2015 spoke out against glyphosate..._
           | 
           | Oz also promoted MLM dietary supplements, antimalarial drugs
           | as COVID treatments, gay conversion "therapy", colloidal
           | silver, and vaccine skepticism. He has zero credibility and
           | cannot be trusted.
        
             | KK7NIL wrote:
             | > > Trust the science.
             | 
             | >
             | 
             | > Science is a process, not a result. Retractions like this
             | promote the integrity of scientific research and evidence-
             | based medicine.
             | 
             | He was obviously poking fun at people who say "trust the
             | science" when what they really mean is "trust these
             | scientits" or, even better, "trust this one study".
             | 
             | Undoubtedly "trust the science" is little more than an
             | appeal to authority when used in a casual debate, not some
             | appeal to skepticism, peer review and testability.
        
               | imoverclocked wrote:
               | "Trust the science" ... always when talking to a flat-
               | earther or similar huckster.
               | 
               | There definitely needs to be more nuance to the phrase in
               | the general case. Eg: "trust established science" Let's
               | be honest though, it's a lack of nuance in some world
               | views that need science as an authority the most.
        
               | Lord-Jobo wrote:
               | "Trust x,y" will also basically never mean "trust,
               | completely, always, equally, and blindly".
               | 
               | Trust the science was a shorthand for "you, or even I,
               | may not understand this thing in perfect detail, but the
               | people working on it do, and they GENERALLY aren't making
               | catastrophic mistakes that you can detect as an amateur.
               | And when these people collectively stand behind a
               | conclusion the odds of it being completely wrong are
               | exceptionally low. We don't have a more accurate
               | alternative regardless. Please stop JAQing off about it"
               | 
               | But writing all of that over and over again is annoying.
               | And a lot of """"critical thinkers"""" can't be bothered
               | to read it. So the shorthand emerges. Sometimes used
               | incorrectly? Definitely.
        
               | KK7NIL wrote:
               | > Let's be honest though, it's a lack of nuance in some
               | world views that need science as an authority the most.
               | 
               | I agree but if they're flat earthers they've already
               | rejected established science, so what's that appeal to
               | authority going to do?
               | 
               | This is why "trust the science" is so memeable, it's a
               | lazy appeal to authority the other party has already told
               | you they don't trust and yet people are shocked when this
               | argument doesn't work.
        
           | DustinEchoes wrote:
           | > The only large cohort study of high quality found no
           | evidence of an association at any exposure level
           | 
           | Was that the retracted study or a different one?
        
           | hshdhdhj4444 wrote:
           | How many retractions has Dr Oz published?
           | 
           | Has he retracted his claim that "raspberry ketones" are a
           | miracle for burning fat in a jar?
           | 
           | Idiots look at people who never admit they were wrong and
           | think those are the people to follow.
           | 
           | People with the slightest bit of intelligence look at the
           | people (or process in this matter) who are constantly
           | checking themselves and willing to admit they were wrong (or
           | in this case misled by frauds) when they find the truth.
           | 
           | Meanwhile, the real issue here is not the science. The real
           | issue here is the American GRAS system, because Europe didn't
           | allow glyphosates because their political system requires
           | stuff going into your food to be proven safe, whereas the
           | American system simply requires it to not be proven harmful.
        
             | DANmode wrote:
             | This is a lot of words to make no real point to who it's
             | replying to.
        
               | hombre_fatal wrote:
               | The guy they replied to didn't make a point, instead
               | threw together some quotes by an HN user and Dr. Oz,
               | relying on you to make the point for them.
        
               | collingreen wrote:
               | Would be more effective to simply ask for a point to be
               | clearly made rather than grandstanding about what stupid
               | people vs people with even slight intelligence believe as
               | a way to try to indirectly insult other posts.
        
           | baq wrote:
           | > The evidence seems to suggest that glyphosate is basically
           | inert in humans
           | 
           | It actually might be the case and it _still_ can be damaging
           | to people by affecting the gut microbiome:
           | 
           | https://www.thelancet.com/journals/lanplh/article/PIIS2542-5.
           | ..
        
             | RealityVoid wrote:
             | > affecting the gut microbiome
             | 
             | That is so vague it can apply to everything. Probably
             | drinking a glass of water affects the gut microbiome.
        
             | sokoloff wrote:
             | I would disagree with the claim/usage of "inert" if it was
             | damaging to gut microbiome.
        
             | tptacek wrote:
             | Did you read the paper? I just did. There's no data in it.
             | It's a broad statement about research directions in
             | glyphosate accompanied by concerns that all chemical
             | agricultural supplements are objects of concern,
             | epidemiologically, with Parkinsonism.
             | 
             | I think the point about the microbiome is well taken, for
             | what it's worth. It's a good response to "humans lack a
             | shikemic acid pathway, which is where glyphosate is
             | active".
        
               | baq wrote:
               | reference [5] (right in the middle of point 3, the one
               | about gut microbiome) links to
               | https://journals.sagepub.com/doi/full/10.3233/JPD-230206
               | which is way too dense for me to unpack in general...
               | 
               | e.g.                    Rotenone Mouse Oral gavage |
               | Firmicutes-to-Bacteroidetes (F/B) ratio, | Rikenellaceae
               | and Allobaculum; | Bifidobacterium in both the caecal
               | mucosa-associated and luminal microbiota community
               | structure [169]
        
               | tptacek wrote:
               | I'm definitely not going to go crate digging through the
               | cites in this paper! I think for the level of discourse
               | we keep here on HN, it's more than enough to note (1)
               | glyphosate targets metabolic pathways animals don't have,
               | but (2) bacteria do have those pathways, which could
               | implicate the gut microbiome. Point taken!
               | 
               | In all these discussions, if I could ask for one more
               | data point to be pulled into the context, it's what the
               | _other_ herbicides look like (my understanding: much
               | worse). I think these discussions look different when it
               | 's "late 20th century SOTA agriculture writ large vs.
               | modern ideal agriculture with no chemical
               | supplementation" than when it's "Monsanto vs. the world".
               | 
               | A very annoying part of the backstory of the "Monsanto
               | vs. the world" framing are people who care about
               | glyphosate not because they have very fine-grained
               | preferences about specific herbicide risks (glyphosate is
               | probably the only herbicide many of these people know by
               | name), but rather because of glyphosate's relevance to
               | genetically modified crops. I'm automatically allergic to
               | bank-shot appeals to the naturalist fallacy; GM crops are
               | likely to save millions of lives globally.
        
               | sbxfree wrote:
               | to build on this further, glyphosate disproportionally
               | targets bifidobacterium and lactobacillus (PMC10330715).
               | It mimics what happens to the gut as people age
               | (PMC4990546) and increasing bifidobacterium, in research,
               | improves dementia symptoms. In the guts of people with
               | allergies, ibs, asthma, and cystic fibrosis there are
               | decreased amounts of certain strains of bifidobacterium.
               | 
               | In mice models, Alzheimer's is transferrable via gut
               | microbiota. (https://www.nature.com/articles/s41380-023-0
               | 2216-7?fromPaywa...).
               | 
               | So to say it messes with the gut is no small thing.
        
           | potato3732842 wrote:
           | >Tptacek in 2018:
           | 
           | Makes me want to punch everyone else on the high score board
           | into a search engine and see how they did.
           | 
           | Kinda funny how the "it kills stuff, it can't be good for ya"
           | luddite crowd turned out to be right all along.
        
             | GeoAtreides wrote:
             | [ On second thoughts, retracted ]
        
               | potato3732842 wrote:
               | While it's not great I vastly prefer that sort of not
               | great behavior to achieving the same results by being one
               | of those people who has crappy opinions and then just
               | cherry picks links to back them up when called out on it.
               | 
               | Probably a good call on the retraction TBH.
        
             | pstuart wrote:
             | Speaking of luddites, I've recently stumbled on posts that
             | point out that the framing of "luddites" was intentionally
             | misleading and that it was never being against technology
             | but how it was wielded.
             | 
             | https://www.brookings.edu/articles/we-should-all-be-
             | luddites...
        
             | kalkin wrote:
             | Did they turn out to be right? Maybe, I'm not familiar with
             | the research here, but no evidence for that has actually
             | been posted. This study being untrustworthy doesn't make it
             | prove its opposite instead.
        
           | mapontosevenths wrote:
           | Retracting a paper showing it's safety isn't the same as
           | proving it is unsafe. I don't see anything here that does
           | that.
           | 
           | The IARC says the 2A designation was "based on "limited"
           | evidence of cancer in humans (from real-world exposures that
           | actually occurred) and "sufficient" evidence of cancer in
           | experimental animals (from studies of "pure" glyphosatese"*
           | 
           | * https://www.iarc.who.int/wp-
           | content/uploads/2018/11/QA_Glyph...
        
           | tptacek wrote:
           | It's been awhile since I've done any reading on glyphosate,
           | which I mostly paid attention to because of a wave of
           | bullshit stories about how Monsanto was suing people over
           | seeds that blew onto their land (that basically never
           | happened). Nothing in the intervening years, including this
           | specific retraction, changes what I think about glyphosate,
           | which is that it's probably safer than the herbicides that
           | are used when glyphosate isn't.
           | 
           | I don't know why you think bringing me into this discussion
           | is useful. If you were thinking that some regulatory agency
           | made decisions based on the persuasiveness of my HN comments,
           | probably no.
           | 
           | I'm generally comfortable being on the other side of whatever
           | Mehmet Oz is talking about.
        
             | rsync wrote:
             | I think it's quite the compliment - you should be
             | flattered!
             | 
             | Unrelated:
             | 
             | I really enjoy "Security, Cryptography, Whatever".
        
               | tptacek wrote:
               | I'm not offended, it's just weird. And thank you! We've
               | got fun stuff coming out. If anybody knows someone
               | involved in GrapheneOS, we'd _really_ like to get their
               | perspective on modern mobile platform hardening. I will
               | repay them in Monsanto Roundup-Ready(tm) gift
               | certificates.
        
               | Aurornis wrote:
               | I agree. It's weird to see HN comments turn into cheap
               | shots (albeit fallacious ones from someone who isn't
               | making a logical argument) against other HN users.
               | 
               | Maybe I'm a little sensitive to this since I've rotated
               | HN screen names a couple times after someone tried to
               | track me down off-site to argue a (rather benign) comment
               | I made about something.
        
             | Teever wrote:
             | Yeah but that's a bit of a motte-and-bailey fallacy isn't
             | it?
             | 
             | Just because the chemical in question is safer than the
             | previously existing alternatives doesn't mean that the way
             | that Monsanto promoted it and marketed it for use and the
             | way people ended up using it because they believed that
             | marketing didn't result in a net greater detriment to
             | society and the ecosystem than if we had adopted totally
             | different pest management protocols that didn't require as
             | many chemicals that a company like Monsanto conveniently
             | sells.
             | 
             | I had a boss at a greenhouse tell me once that his old-
             | timey agriculture prof at a big university would swear by
             | the safety of glyphosate and he would literally drinking a
             | shot glass of the stuff in every first year class like he
             | was that dude who drank H. pylori to prove ulcers were
             | caused by an infection.
             | 
             | This kind of insane grandstanding where a professor openly
             | drinks herbicides for years in university classrooms came
             | from absurd marketing from Monsanto and neither of these
             | things have any place in our society.
             | 
             | Monsanto had a financial interest to make that professor
             | into a fervent Jonestown-esque believer of their product
             | and the end result was that spread that fervour to
             | thousands of students who went out into the industry and
             | figured that if it's alright for that guy to drink it then
             | it must be alright to spray that shit everywhere as often
             | as they want.
             | 
             | The downstream effect of that is you're on HN in 2018
             | advocating for glyphosate and then again in 2025 when
             | someone points out how ubiquitous confidentially incorrect
             | opinions about glycophosate are.
        
               | Aurornis wrote:
               | > Yeah but that's a bit of a motte-and-bailey fallacy
               | isn't it?
               | 
               | Speaking of motte-and-bailey fallacy, pivoting from "Dr
               | Oz was right about glyphosate" to this run-on claim:
               | 
               | > Just because the chemical in question is safer than the
               | previously existing alternatives doesn't mean that the
               | way that Monsanto promoted it and marketed it for use and
               | the way people ended up using it because they believed
               | that marketing didn't result in a net greater detriment
               | to society and the ecosystem than if we had adopted
               | totally different pest management protocols that didn't
               | require as many chemicals that a company like Monsanto
               | conveniently sells.
               | 
               | Is a textbook motte-and-bailey play. The original
               | argument wasn't that "society and the ecosystem would be
               | better if everyone didn't use chemicals". The claim above
               | was that anyone who said there wasn't evidence that
               | glyphosate caused cancer was wrong and Dr. Oz was right.
               | 
               | And _that_ argument was a fallacy in itself. The
               | retraction of a single paper is not equivalent to saying
               | that glyphosate _is_ dangerous, that it causes cancer, or
               | that Dr. Oz was right.
               | 
               | These threads are frustrating because a small number of
               | people are trying to share real papers and talk about the
               | subject, but it's getting overrun with people who aren't
               | interested in discussing science at all. They've made up
               | their minds that chemicals are bad, glyphosate causes
               | cancer, and Dr. Oz was right and they're here to push
               | that narrative regardless of what the content of the
               | linked article actually says.
        
               | tptacek wrote:
               | I don't know what you're talking about. None of my
               | opinions about glyphosate have anything to do with some
               | stunt where somebody drank glyphosate. I wouldn't drink
               | glyphosate. Nothing has happened between 2018 and 2025
               | that has changed my (not very strongly held) beliefs that
               | glyphosate is broadly safer than the herbicides that get
               | used when it isn't. I also don't give a shit how Monsanto
               | is promoting glyphosate; Monsanto's success or failure as
               | an enterprise simply doesn't factor into my thinking _at
               | all_.
        
               | Teever wrote:
               | I'm not saying your views came from some professor
               | drinking glyphosate. I'm saying the social and regulatory
               | environment around glyphosate was distorted by decades of
               | industry driven messaging, ghostwritten research, and
               | normalization of reckless demonstrations.
               | 
               | That environment shaped the baseline assumptions many of
               | us including farmers, scientists, regulators,
               | journalists, and yes even minor-celebrity HN commenters
               | such as yourself.
               | 
               | My point is that the issue isn't whether glyphosate is
               | 'safer than alternatives' but whether the entire
               | ecosystem of evidence and perception surrounding it was
               | manipulated. This paper that we're talking about is but
               | one example of that. So the question isn't about your
               | personal motives but how you came to believe what you
               | believe about Monsanto products and who stands to gain
               | from you believing those things and expressing them on
               | social media.
        
               | tptacek wrote:
               | _That environment shaped the baseline assumptions many of
               | us including [...] yes even minor-celebrity HN commenters
               | such as yourself._
               | 
               | No it isn't.
        
             | CGMthrowaway wrote:
             | Very US-centric POV. The herbicides that would be used in
             | the US to replace glyphosate, that are potentially worse
             | (paraquat/diquat, atrazine, and 2,4-D), are are already
             | banned in the EU.
             | 
             | If the EU were to officially ban glyphosate, their food
             | supply would increase in quality as a result, since these
             | worse pesticides are not available.
             | 
             | The US needs to catch up. Eliminating glyphosate is not a
             | one-shot kill for human health and never meant to imply
             | that
        
               | quickthrowman wrote:
               | Sounds like you might be confused as to which crops use
               | glyphosate as an herbicide, it's not being used on
               | vegetables and fruits being sold in the produce section,
               | so it would do nothing for the quality of European
               | produce. It's possible that glyphosate overspray touches
               | some human foods crops, but I wash my produce before
               | eating it, I hope you do too.
               | 
               | Here is a list of plants that have glyphosate tolerant
               | varieties: _soybeans, alfalfa, corn, canola, sugar beets,
               | and cotton._ There is no glyphosate tolerant wheat plant.
               | 
               | These plants are used to make ethanol, sugar, soy animal
               | feed, canola oil, cotton fabric, and feed corn. Humans
               | consume canola oil and sugar, both of which are refined
               | in a distillation process. Possibly some of the corn ends
               | up as cornmeal or corn flour. All of the soy and alfalfa
               | are sold as animal feed.
               | 
               | I'm not afraid of glyphosate or microplastics until the
               | evidence shows otherwise.
               | 
               | Edit: I am out of replies, I hadn't considered either of
               | those routes for glyphosate to enter the human food
               | supply. The concentration of glyphosate in a cow that
               | eats feed grown with glyphosate has to be much more
               | concentrated as well. Thanks for replying, my apologies
               | for making a bad assumption.
        
               | CGMthrowaway wrote:
               | Confused where you think I said fruits and vegetables.
               | There is glyphosate in beef and other meat, just because
               | an animal eats it does not wash it away.
               | 
               | And glyphosate is also used for burndown and/or
               | dessication on a number of non-glyphosate tolerant crops
               | such as wheat, oats, beans, potatoes, etc that go
               | directly to the grocery store
        
               | tptacek wrote:
               | By the logic you're using here, the epidemiological
               | impact of glyphosate should be widely observed across the
               | population (you're going so far as to look at traces of
               | it left in the meat supply). And yet the correlations we
               | have all tend to focus on agricultural workers dealing
               | with it in large volumes directly. Can you square that
               | circle?
        
               | CGMthrowaway wrote:
               | Study funding (or lack of)
        
               | ephelon wrote:
               | While there isn't a commercially grown glyphosate
               | tolerant wheat; there is a significant pathway for
               | glyphosate into the wheat you eat through the process of
               | desiccation[1]. It is common practice to kill the plant
               | with an herbicide shortly before harvest, which helps to
               | maximize yield.
               | 
               | Personally, I suspect that many people who present as
               | wheat/gluten sensitive may in fact be reacting to the
               | herbicides present in the wheat.                 [1]
               | https://en.wikipedia.org/wiki/Crop_desiccation
        
             | samdoesnothing wrote:
             | The precautionary principle clearly states that if you have
             | a chemical that kills living things and you have a company
             | who stands to make a lot of money off of this chemical as
             | long as it's safe for humans, that you should be very very
             | careful about it. Probably should be avoided until there is
             | not just proof from a lab or from paid off scientists.
             | 
             | Kind of crazy that this isn't just obvious to everybody.
        
               | tptacek wrote:
               | It's not obvious to everybody because it's false. The
               | Precautionary Principle is deeply problematic. For
               | instance: it is generally interpreted to favor existing
               | fossil fuel power sources over nuclear, despite the fact
               | that fossil fuel power generation and extraction kills
               | enormous numbers of people every year. Precautionary
               | Principle thinking is extremely vulnerable to narrative
               | capture. A closer-to-home example: Precautionary
               | Principle thinking cautions against adoption of
               | genetically modified crops. The status quo agriculture it
               | favors instead have both lower yields (and thus greater
               | ecological impact) and _more_ pesticide /herbicide use.
               | 
               | Precautionary Principle thinking, taken on its face,
               | would have immediately halted the rollout of COVID-19
               | vaccines (VAERS data almost immediately showed things
               | like blot clots), because Precautionary thinking tends to
               | fixate on individual risks rather than a global risk
               | picture; fortunately, Precautionary thinking failed to
               | win the day and vaccines saved millions of lives instead.
               | Note that this example flunks your Extended Precautionary
               | Principle logic: there were certainly big companies that
               | stood to profit from the right decision there!
               | 
               | You can put together a coherent and persuasive defense of
               | the Precautionary Principle, but if you just cite it in
               | passing and say things like "crazy everyone doesn't agree
               | with me about this", expect pushback.
        
           | Aurornis wrote:
           | > Trust the science.
           | 
           | I haven't kept up with research. Do you have any actual
           | science showing that glyphosate is a carcinogen?
           | 
           | Retraction of a paper doesn't automatically mean the opposite
           | is true. It doesn't make Dr. Oz's methods right.
           | 
           | Using the retraction of a paper to elevate a known
           | pseudoscience pusher who constantly makes claims without
           | scientific basis is intellectually dishonest. It's a common
           | tactic among pseudoscience and alternative medicine peddlers
           | who think that any loss for the other side is validation for
           | their beliefs.
        
             | CGMthrowaway wrote:
             | Non-Hodgkin lymphoma odds ratio 1.41-1.45 (AKA 41-45%
             | higher relative risk):
             | https://pubmed.ncbi.nlm.nih.gov/31342895/
             | 
             | NHL odds ratio 2.26:
             | https://pubmed.ncbi.nlm.nih.gov/18623080/
             | 
             | Positive trend of NHL risk with exposure:
             | https://pubmed.ncbi.nlm.nih.gov/12937207/
             | 
             | 7x risk of follicular lymphoma in those ever exposed:
             | https://pmc.ncbi.nlm.nih.gov/articles/PMC8082925/
        
           | zug_zug wrote:
           | On what basis should we blindly trust this fao.org study as
           | conclusive? If Monsanto ghost-wrote one paper, how many other
           | studies did it put its finger on the scale for?
        
         | DANmode wrote:
         | It takes time for conspiracy theory to become conspiracy fact.
        
       | ChrisMarshallNY wrote:
       | _> The scientists are suspected of having signed a text actually
       | prepared by Monsanto._
       | 
       | I think that this kind of thing has been happening for decades.
       | I'm hoping that these types of things start getting discovered,
       | now that advocacy orgs can do things like run an LLM on a huge
       | pile of old records, reports, and news articles.
        
         | observationist wrote:
         | Can even do things like stylometric analysis, and make good
         | predictions about the authorship of any particular line or
         | paragraph or paper. Semantic search and RAG aren't the only
         | thing you can do with a high quality vector database system.
        
         | CGMthrowaway wrote:
         | Many such cases. Aspartame, BPA, tobacco, Paxil (paroxetine),
         | neonics (pesticide) all have documented trails of how
         | researchers and policy makers were working for the industry and
         | often hiding the fact
        
       | reeredfdfdf wrote:
       | I can understand the use in agriculture, but I've never
       | understood why anyone would use the stuff on their own lawn. Who
       | cares if there are some weeds growing, when you can cut them down
       | with lawnmower anyway?
       | 
       | Heck, my relatives in the countryside don't even have lawn, they
       | just let the dandelions and other natural plants grow, and only
       | use lawnmower in areas where they need to walk. Much better for
       | the environment, and even looks pretty nice. Of course areas
       | where they grow food or fancier flowers require some digging to
       | keep weeds away.
        
         | Stevvo wrote:
         | Cutting dandelions with a lawnmower just sends the seeds
         | everywhere making the problem worse.
        
           | quesera wrote:
           | Only if you wait for them to go to seed. If it's important to
           | you, don't do that.
           | 
           | I let them grow. Dandelions are harmless.
        
         | WillAdams wrote:
         | Some neighbors spray poison ivy --- I just cover it with
         | stones/bricks when I see it.
        
       | quesera wrote:
       | Peer-reviewed science is the best scale of measurement we have.
       | When that standard is subverted with intent to deceive, there
       | should be severe repercussions for the beneficiaries.
       | 
       | There have also been numerous, extremely confident and
       | impassioned, defenses of Monsanto and glyphosate here on HN over
       | the years. These might deserve some reexamination.
        
         | hombre_fatal wrote:
         | Imo, the best defense of glyphosate is that if occupational
         | cohorts can't even be shown to have a strong, reproducible jump
         | in effects like cancer at 100s of times the exposure than
         | genpop, then we shouldn't go Kony 2012 on dietary exposure.
        
           | quesera wrote:
           | OK, but that is _not_ how you properly test pesticides for
           | safety.
        
             | hombre_fatal wrote:
             | Well, don't leave me hanging.
             | 
             | Though I didn't prescribe a test. I set a low bar of
             | evidence that we should at least pass before we Kony up
             | over our bowl of Cheerios.
        
               | quesera wrote:
               | Are you asking me to describe modern pesticide safety
               | testing protocols? I'm not qualified to do that
               | authoritatively.
               | 
               | But I'm certain that "spray it everywhere for 30 years
               | and see if people die" is not the way.
               | 
               | Bypassing the proper protocols, publishing dishonest
               | research, is the issue under discussion today. Glyphosate
               | might be safe, or safe enough. Proper research could
               | reveal more subtle effects than mortality numbers.
        
               | hombre_fatal wrote:
               | I still don't understand what you're responding to.
               | 
               | Glyphosate is already out there.
               | 
               | We have large papers that look into occupational and
               | dietary exposures of real world cohorts, and they don't
               | converge on much of anything that should make us
               | concerned about our dietary exposure.
               | 
               | Yet you have some sort of "testing protocol" in mind that
               | would somehow be more robust than the analyses already
               | being done on real world populations that were
               | inconclusive?
               | 
               | At least pitch a rough idea of what these experiments
               | look like.
        
               | quesera wrote:
               | This is outside my field.
               | 
               | If you tell me that EPA doesn't have a better process
               | than "dunno, seems OK", then I'll humbly defer.
               | 
               | Not holding EPA up as infallible, just asserting that
               | intentionally-deceptive research should not be tolerated
               | -- and should demand a higher degree of skepticism of
               | other research from the same entities or with the same
               | beneficiaries.
        
               | hombre_fatal wrote:
               | > This is out of my field.
               | 
               | This is what I've come to expect from discussion on
               | things like glyphosate, cholesterol, seed oils, etc.
               | 
               | You supposedly are raising an issue, yet you can't even
               | squeak out the smallest concrete claim.
               | 
               | You're "in the field" enough to claim they didn't do the
               | proper "testing protocols", but when simply asked what
               | you mean by that or how it's different from the existing
               | research, you're so "out of the field" that you can't
               | even elaborate on the words you just used -- that's a
               | task for the experts.
        
               | quesera wrote:
               | I never claimed to be "in the field" or anywhere
               | adjacent. One does not need to be an expert to know that
               | dishonest research is bad for the world. Why are you OK
               | with this??
               | 
               | And I'm not raising an issue. The article is.
               | 
               | For the record, I do not have an opinion on the safety
               | profile of glyphosate _at all_. And I 've spent zero time
               | even wondering about cholesterol, seed oils, etc. You're
               | dropping me into the middle of the wrong argument.
               | 
               | I do have strong opinions about research integrity, and
               | this story about Monsanto is unfavorable. Do you disagree
               | with that?
        
               | zug_zug wrote:
               | Well we have no idea what the effects of glyphosate are
               | because almost everybody has it in their system. Is it
               | possible that's why autism, depression, add are so much
               | higher among us than amish? Who's to say?
        
             | phil21 wrote:
             | The public discourse on glyphosate is useless. As witnessed
             | by calling it a pesticide, which is quite common among
             | those most vocal against its use.
             | 
             | Less is more when it comes to chemicals, which is why
             | reasonable uses of glyphosate seems to be the best we have
             | come up with so far as a species - regardless of abuses of
             | the chemical.
             | 
             | It's probably the most studied herbicide on the planet at
             | this point with very little evidence that it causes human
             | health issues when used as intended. Doesn't mean it's zero
             | risk, but we also feed an incredible number of people off a
             | very small amount of landmass at this point in history.
        
               | quesera wrote:
               | Herbicides are pesticides. Are you implying that I made a
               | mistake with that word? I did not.
               | 
               | Your other points are valid, but would you advocate for
               | dishonest research to be acceptable as evidence that a
               | pesticide is ready for widespread human field trials?
               | 
               | Assuming you would not, then I think you'd agree that
               | there should be repercussions. Monsanto is not Uber for
               | agriculture.
        
               | chrisbrandow wrote:
               | Herbicides kill plants, pesticides kill bugs, right?
        
               | quesera wrote:
               | Weeds are pests, as defined by the EPA at least.
               | 
               | https://www.epa.gov/minimum-risk-pesticides/what-
               | pesticide
        
         | red-iron-pine wrote:
         | HN is plagued by bots and shills. Arguably is one of the main
         | selling points of the site -- it's a news aggregator run by
         | Angel Investors
         | 
         | Why would you expect anti-corporate narratives? If I'm F500 and
         | am trying to sway opinion here is one of the places I'd direct
         | my marketing drones to hit hard, as the tech-bro demographic
         | would then parrot it everywhere else
        
       | lenerdenator wrote:
       | Scientific fraud here feels like a reaction to people not
       | understanding the bargain we have to make given the needs of the
       | world's population. It should be punished, but I can't help but
       | feel there's a point that doesn't get discussed.
       | 
       | The thing that sucks about this is, past a certain point,
       | herbicide/pesticide safety doesn't matter.
       | 
       | We use this stuff, at least industrially, to grow food. Humans
       | need food to live. More food, generally speaking, means healthier
       | humans, Western processed food trends notwithstanding. There's
       | the consumer market that uses glyphosate to make yards pretty in
       | North America, but that's not the real reason we invent
       | herbicides, and yards themselves are problematic, so we'll ignore
       | that for now.
       | 
       | It's not an accident that global starvation deaths have decreased
       | since the 1960s[0]. We started applying chemistry and automation
       | to agriculture. Food security and yields went up. Some of these
       | chemicals we use are, over the long term with chronic low-level
       | exposure, hazardous to human health.
       | 
       | However, they're still less immediately hazardous to the general
       | public than malnutrition and starvation, so the question becomes
       | this: Do you want millions to die of malnutrition _now_ , or do
       | you want an unknown number of people to die of various health
       | issues (particularly cancer, though there are others) caused by
       | chemical exposure at an unknown point in the future, and gamble
       | that medicine will, some day, be able to treat or cure the health
       | issues?
       | 
       | [0]https://ourworldindata.org/famines
        
       | myrmidon wrote:
       | This kind of shit happened before, is happening right now and is
       | going to happen again. Something needs to be done.
       | 
       | IMO the best way to stop companies from messing with science and
       | law is to hold them accountable for the actual damage, ideally
       | both company leadership (CEO goes to prison) and shareholders
       | (potentially lose everything) when it comes to light that
       | companies prevented regulation or research into negative
       | externalities that they caused.
       | 
       | We had the exact situation with leaded gas (paid shills, lawfare
       | and discrediting campaigns against critical scientists), the
       | exact same thing is happening right now with the fossil fuel
       | industry and if we don't change anything it is invariably gonna
       | happen again.
        
       | wslh wrote:
       | Science and law (in snail motion) are clearly broken. The paper
       | "Association between Cancer and Environmental Exposure to
       | Glyphosate" [1] shows population groups with significantly higher
       | cancer incidence linked to glyphosate exposure. When findings
       | like these struggle to gain broad acknowledgment, it becomes
       | evident how powerful companies can still "hide the sun with their
       | hands"
       | 
       | [1] Association between Cancer and Environmental Exposure to
       | Glyphosate
        
       | Beijinger wrote:
       | I have a feeling that it is this causing the collapse of our
       | insect population.
        
         | chrisbrandow wrote:
         | If so, presumably because it kills the weeds that feed the
         | bugs.
        
           | Beijinger wrote:
           | Research from the National Institutes of Health (NIH) and
           | related studies shows glyphosate negatively impacts bees by
           | disrupting their gut microbiota, weakening immune responses,
           | impairing learning/memory, affecting foraging behavior, and
           | increasing mortality, with effects seen from both pure
           | chemical and commercial formulations at environmentally
           | relevant levels, impacting both adult bees and larval
           | development.
        
       | shrubble wrote:
       | So any misdirection has served its purpose.
        
       | chrisbrandow wrote:
       | I'm not actually familiar with current state of scientific
       | research. Are there any quality studies that contradict the
       | ghost-written report?
       | 
       | I understand the valid reasons for pulling the study, but that
       | does nothing to specifically address its claims or evidence.
        
       | lisbbb wrote:
       | The same thing is going to happen with that covid "vaccine" study
       | that claims there were no excess deaths found. Wait and see.
        
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