[HN Gopher] Ioannis Yannas invented artificial skin for treatmen...
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       Ioannis Yannas invented artificial skin for treatment of burns-dies
       at 90
        
       Author : bookofjoe
       Score  : 115 points
       Date   : 2025-11-01 17:18 UTC (11 days ago)
        
 (HTM) web link (news.mit.edu)
 (TXT) w3m dump (news.mit.edu)
        
       | toomuchtodo wrote:
       | https://en.wikipedia.org/wiki/Ioannis_Yannas
        
         | wnissen wrote:
         | If you have a weird phoneme / meaning mapping brain like mine,
         | I would note that he is not the doctor who is known for the
         | "replication crisis". Even though Ioannis means John in Greek.
         | Took me a second to tease that out.
         | 
         | https://en.wikipedia.org/wiki/John_Ioannidis
        
       | infinet wrote:
       | To understand the significance of artificial skin, first consider
       | all sorts of bad things that happen after deep burn. The dead
       | tissue in a burn wound can release toxins and provide nutrients
       | for bacteria to grow, which in turn can spread toxins and
       | infection throughout the body, eventually causing multiple organ
       | failure and death. Early treatment of deep burns focuses on
       | interrupting this cascade reaction by removing the dead tissue.
       | The now-cleaned wound needs to be covered. Skin from many
       | species, including chicken, rat, pigeon, cat, dog, frog, cow, and
       | pig, has been tested, and pig skin was found to be the best. As
       | the wound's condition improves, healthy skin from the same
       | patient is grafted or seeded onto the wound to assist healing.
       | Although pig skin is still widely used, the biggest problem is
       | that it is from a different species and therefore can be immune
       | rejected. Gene-edited pig skin helps, but it may still require
       | immunosuppressive therapy, which is not helpful when the patient
       | is at high risk of infection.
       | 
       | Artificial skin has the potential for better temporary wound
       | cover, and ideally, it can promote healing without skin grafting
       | or using less skin for grafting.
        
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       (page generated 2025-11-12 23:00 UTC)