[HN Gopher] Attention lapses due to sleep deprivation due to flu...
       ___________________________________________________________________
        
       Attention lapses due to sleep deprivation due to flushing fluid
       from brain
        
       Author : gmays
       Score  : 482 points
       Date   : 2025-10-31 13:14 UTC (9 hours ago)
        
 (HTM) web link (news.mit.edu)
 (TXT) w3m dump (news.mit.edu)
        
       | rtaylorgarlock wrote:
       | Long live healthy sleep for brain health, and thank goodness
       | light exercise helps this same glymphatic system.
        
         | cestith wrote:
         | ISTR that light exercise also helps with quality of sleep.
        
           | HPsquared wrote:
           | It stands to reason.
        
             | stOneskull wrote:
             | It lays to drain.
        
       | cdelsolar wrote:
       | I slept around 5 hours last night split up into two periods
       | because my baby daughter woke up crying from fever and wanted to
       | play / was hallucinating / etc. She's totally fine now but I am
       | wondering if there is a correlation between dementia and having
       | kids.
        
         | aethrum wrote:
         | Probably negatively correlated cause you have someone to
         | interact with in your old age/better chance of community :)
        
           | skeeter2020 wrote:
           | Also I think of (hopefully at least one of) my three kids as
           | a diversed retirement portfolio :)
        
         | arethuza wrote:
         | I remember this quote from when we had young kids:
         | 
         |  _" Insanity is hereditary. You can get it from your
         | children."_
         | 
         | And then as soon as they are in their 20s and reasonably self
         | sufficient we had to get a puppy to keep me sane!
        
           | spockz wrote:
           | Long days and short years.
           | 
           | Did you have empty nest syndrome?
        
             | arethuza wrote:
             | More like empty head syndrome - but getting a dog was the
             | best thing I've done in years.
        
         | sarchertech wrote:
         | I'm on my 3rd (she's 1 week old today) at 42. With the first 2
         | it was only terrible for the first couple months. Once I just
         | got used to going to sleep at 9:30 I was mostly fine.
        
           | micromacrofoot wrote:
           | Yeah that's the trick, sleep asap
        
           | grumpy-de-sre wrote:
           | We're expecting our first in a few months.
           | 
           | NGL I'm low key wondering if my messed up natural rhythm of
           | 9pm-4am is going to be potentially handy.
        
             | zurichisstained wrote:
             | I have a similar natural rhythm, or I should say "had". For
             | the first year, especially the first few months, it was a
             | godsend (for my wife, especially), but now that we're in a
             | fairly consistent sleep routine with our two year old
             | (~8pm-7am), I've shifted to something more like 8pm-1am out
             | of necessity.
             | 
             | Although... I was up until 4am and got up at 6:30am and
             | feel surprisingly great, so it still happens from time to
             | time. :)
        
             | Tade0 wrote:
             | As a father of two I would say "nope", primarily because
             | you won't be deciding the rhythm. Best you can do is
             | coordinate sleep with your partner so that there's at least
             | one somewhat functioning parent at all times.
             | 
             | As I'm typing this my 1.5yo is napping. I had maybe 6h of
             | sleep but I'm after (part time) work and at home already,
             | so I should probably nap as well.
             | 
             | Can't. My adult body won't go to sleep right now even
             | though I'm feeling drowsy because it's too bright, too loud
             | and chiefly I already had too much caffeine in the morning
             | and I have like 15 minutes until I'll have to head out to
             | collect my older child from preschool.
             | 
             | My SO is knocked out cold at the moment though, so I'll be
             | relying on her this evening.
        
         | debo_ wrote:
         | This kind of fear is a quick route to insomnia. One of the most
         | effective ways to reduce sleep is to worry about it.
        
           | grumpy-de-sre wrote:
           | And when that happens, of course HN has the answer
           | https://news.ycombinator.com/item?id=15997016
        
             | debo_ wrote:
             | I think CBTI is pretty horrible but I'm happy it works for
             | some people.
             | 
             | There's so much helpful stuff out there now it's rather a
             | blessing.
        
         | Mizza wrote:
         | Memory loss from sleep deprivation is an evolutionary
         | advantage. If you remembered how rough the first few months of
         | new children are, you wouldn't do it again.
        
         | zoeysmithe wrote:
         | I mean the baby stage doesn't last very long. I dont even
         | remember the sleepless nights from my own kids anymore lol
         | 
         | Chronic sleep deprivation is the larger issue. And how we
         | really don't have treatments on how to fix that, and how
         | ultimately sleep phase issues are a social issues (being forced
         | to follow a fixed modern schedule). Not to mention how closely
         | that's tied to ND people. So a lot of us deal with sleep issues
         | since we were little, but work and school dont give us the
         | flexibility we need. For example, flex hours could be helpful
         | here. I would rather work 10am to 6pm or 11am to 7pm most days.
         | Or 5-6 hours during the day and 2-3 hours late at night.
        
           | chasebank wrote:
           | "Chronic sleep deprivation is the larger issue. And how we
           | really don't have treatments on how to fix that"
           | 
           | Sure we do, however, not everyone is willing to hike 20-30
           | miles a day and sleep in a tent. It's not practical but it is
           | very effective.
        
             | zoeysmithe wrote:
             | Physically exhausting yourself isnt a solution. Its
             | tangential to the real issue. Its a bit like suggesting you
             | can solve anxiety caused by trauma by drinking large
             | amounts of alcohol everyday. No, instead we should be
             | treating trauma. Its like putting autistic kids through
             | rough ABA therapy, no instead we should finding
             | accommodations and support for autistic people.
             | 
             | People have natural sleep rhythms. Society should conform
             | to that, instead capitalism demands we conform to what it
             | deems profit maximizing.
        
               | chasebank wrote:
               | Not physically exhausting yourself is the real issue.
               | It's our natural state as humans. We're not meant to be
               | staring at screens having discussions about chronic sleep
               | deprivation on an internet forum, we're meant to be
               | outside moving our bodies.
        
               | sureglymop wrote:
               | I agree with you. I regularly have strong insomnia and I
               | have tried physical exhaustion.
               | 
               | It usually works for the first few days of doing it but
               | then it's like my body (probably moreso my mind) gets
               | used to it and it doesn't help with sleep anymore.
               | 
               | Arguably it feels even more unhealthy because it's like
               | my body is fully exhausted and tired but my mind won't
               | let me sleep so no restoration can happen.
        
           | randerson wrote:
           | I suffered chronic insomnia most of my life and seen my fair
           | share of experts and read a few books about it. There are
           | definitely treatments for the majority of insomniacs.
           | 
           | Sleep deprivation is often caused by alcohol, inconsistent
           | sleep/wake times, high color temperature lighting (>3000K) in
           | the hours before bed, failure to spend time outdoors in
           | natural light in the morning, temperature too warm (68F is
           | ideal), caffeine (or other stimulants) in the afternoon,
           | associating the bedroom with tasks other than sleep and sex,
           | or simply spending too much time in bed.
           | 
           | Following doctor's advice for the last one: Start by going to
           | bed at, say, 1am and waking up at 6am. Follow this without
           | fail for a few weeks. You'll be exhausted but keep at it.
           | Eventually you should find yourself falling asleep quickly.
           | If you wake up exhausted, pull back bedtime by 10 minutes. Do
           | this for a week. Rinse and repeat until you are waking up at
           | 6am refreshed. That is how you determine how many hours your
           | body needs to sleep, and how long you should be in bed.
           | Helped me.
        
             | zoeysmithe wrote:
             | I'm autistic with delayed sleep-wake cycle. For autistics
             | DSWPD is pretty common. There's just no fixing that for the
             | vast majority of us, we're just expected to follow strict
             | schedules and if we are underslept, too bad for us.
             | 
             | ND people get this pretty badly. 2023 study: The incidence
             | of sleep problems in ASD patients ranges from 32 to 71.5%,
             | especially insomnia, while an estimated 25-50% of people
             | with ADHD
             | 
             | Insomnia is different, but tbf, insomnia for many people
             | can't be treated well or if not at all. CBT is helpful if
             | you look at the studies and ignore the follow up studies
             | showing relapses between 40-70%. We can stuff people with
             | melatonin and hypnotics but after a while that no longer
             | works. So looking at this, it looks like things like drugs
             | and CBT can help 70% of insomnia sufferers but the relapse
             | rate is as high as 70%, so we're looking at people who can
             | actually be cured as low as 15-20% of total insomnia
             | sufferers.
             | 
             | Its not caffeine or screens for us, its just how the
             | machinery of the human body works. This is like telling a
             | depressed person to just 'cheer up.' I'm glad that worked
             | for you, but your story is just an anecdote, and the
             | science for this is still pretty dismal unfortunately.
             | 
             | The science can't work because at this point we're going
             | against our nature. A lot of people cannot subscribe to a
             | modern industrialized sleep schedule because its not
             | natural for us to have extremely strict sleep and wake
             | times.
        
         | aliljet wrote:
         | What have you done when your toddler wakes up at random hours
         | during the night to interrupt your sleep and come and play?
         | That's what has truly obliterated our sleep. Everything else
         | was a passing fad that was minimally painful at best..
        
         | freedomben wrote:
         | Ah, those days were the absolute grinder for me. How a precious
         | and sweet little baby girl can become an absolute monster all
         | night long, and then wake up the next day back to her normal
         | self while leaving me a hollowed out mess of a human is a
         | mystery for science to solve someday.
        
           | cdelsolar wrote:
           | aren't they the best though? but yeah, back to the grind, and
           | now i also have her respiratory disease and am trying to
           | launch my startup off the ground ...
        
       | ferguess_k wrote:
       | I wonder if a 30-min nap improves the situation. But I need to
       | tell the brain to hold the flushing until the nap.
        
         | rtaylorgarlock wrote:
         | There's controversy over exact mechanisms involved in
         | glymphatic function, so suffice it to say that _allegedly_ even
         | just NSDR  / yoga nidra will engage a rest deep enough for
         | glymphatic function to engage/improve
        
           | DenisM wrote:
           | I was disappointed the article didn't mention that. Can you
           | give me some pointers. I will use Google but HN curated
           | content is often a better starting point. :)
        
         | JKCalhoun wrote:
         | Anecdotally, it seems to. I have laid down and closed my eyes
         | even for a short while. And believe that I have even had a
         | "flushing" sensation, that feels like a mental fog being lifted
         | (or "drained", I guess).
         | 
         | I pop up 5 minutes later and feel completely refreshed.
        
           | nullstyle wrote:
           | Fwiw, i have the opposite experience of napping. Napping adds
           | to mental fog for me especially for the hour immediately
           | after napping. Its not until several hours later that i
           | actually experience any loss of mental fog or increase in
           | clarity.
        
             | g-b-r wrote:
             | It probably depends on how much sleep you're lacking, and
             | how long the nap is.
             | 
             | My experience after sleeplessness nights is that even few
             | seconds help significantly, especially when you're almost
             | unable to function anymore.
             | 
             | If the nap lasts longer than 30 minutes, though, you have a
             | good chance of feeling groggy afterwards.
        
           | ferguess_k wrote:
           | I had the same experience. The only trick is to keep it
           | short, like 5-10 minutes. Any longer and the nap may bring
           | negative impacts.
        
           | assimpleaspossi wrote:
           | Agree though it's 10 minutes for me.
           | 
           | When I owned some property out in the country, it was a 2 1/2
           | hour car trip to get there. Sometimes I just couldn't finish
           | the drive home but pulling over to the side of the road for a
           | 10-minute nap made me feel fully refreshed.
        
           | 256_ wrote:
           | I do something similar, although there's an added peculiarity
           | when I do it. I lie down for 5 minutes and wake up 9 hours
           | later.
        
         | gwbas1c wrote:
         | > I wonder if a 30-min nap improves the situation.
         | 
         | I pretty much wait until I feel drowsy, and then take a 15-30
         | minute nap
        
       | jongjong wrote:
       | Good to know that the brain finds a way to flush itself while
       | awake. I think I've become pretty good at putting unused parts of
       | my brain to sleep while awake. My brain is like that of a dolphin
       | now.
       | 
       | But on rare occasions (like a couple of times a year), I get
       | migraine auras and stuff disappears from my field of view. Can
       | last about an hour. I feel like that's my visual cortex falling
       | asleep.
        
       | paglaghoda wrote:
       | Rest in peace to all the college dudes covering the whole
       | syllabus within 24 hours of the exam
        
         | wslh wrote:
         | It is always great to follow the instructions from a
         | psychiatrist [1].
         | 
         | [1]
         | https://thelastpsychiatrist.com/2007/08/how_to_take_ritalin_...
        
           | plmpsu wrote:
           | I miss her.
        
             | MarcelOlsz wrote:
             | What happened? Did they pass or something or just stop
             | posting or what?
        
               | _--__--__ wrote:
               | TLP was doxxed in a way that threatened their real life
               | psychiatry practice, briefly blogged on Tumblr under a
               | different psuedonym, and has since had little online
               | presence other than rare tweets and randomly dropping a
               | self-published book on Amazon (_Sadly, Porn_ by 'Edward
               | Teach').
        
           | thesmtsolver wrote:
           | This is just outdated, bad and dangerous advice that a ton of
           | recent research invalidates.
           | 
           | 1. Ritalin, and other stimulants are not cognition enhancing
           | for non-ADHD adults and may in fact do the opposite.
           | 
           | https://www.cam.ac.uk/research/news/smart-drugs-can-
           | decrease...
           | 
           | 2. > Because the doctor will rigorously apply artificial and
           | unreliable diagnostic categories backed up by invalid and
           | arbitrary screens and queries to make a diagnosis. So after
           | this completely subjective and near useless evaluation is
           | completed, your doctor should be able to exercise prudent
           | clinical judgment to decide if Ritalin could be of benefit.
           | 
           | What else can you do for psychiatric conditions? We don't
           | have a magic ADHD-o-meter but know that it statistically
           | impacts lifespan, health, etc. Even for more objective
           | measures like blood glucose, BP, BMI, clinical interventions
           | are based on discrete thresholds that don't exist in nature.
        
         | znpy wrote:
         | Not a college dude, but i used to work on shits (including
         | night shifts) and adjusting to and from a five-nights
         | (23:30-07:30) shift isn't that pleasant either.
        
           | nfriedly wrote:
           | I think you meant to say "...I used to work on _shifts_... "
           | 
           | That, or maybe try a laxative.
           | 
           | (Man, if ever there was a time I wanted emoji support on HN,
           | this is it!)
        
       | kurisufag wrote:
       | anecdotally, i never feel better than when i haven't slept. spent
       | 8pm tuesday -- 8pm thursday this week awake nursing cheap energy
       | drinks, and not only could i manage a higher-than-usual level of
       | focus, i was genuinely content.
       | 
       | bombed a midterm halfway though, but at least i felt good about
       | it.
        
         | barrenko wrote:
         | Well, not sleeping through the night, you'll feel genuinely
         | euphoric around dawn, it's one of the most immediate "cures"
         | for clinical depression.
        
         | jcims wrote:
         | I've got pretty bad ADHD and I find that my mind is more quiet,
         | focused and productive on mornings after a night of 2-4 hrs of
         | sleep than it has ever been on meds or anything else. It all
         | falls apart by the afternoon, but for a while it's a nice
         | feeling.
        
         | 90ne1 wrote:
         | I see the same thing in myself.
         | 
         | I've attributed it to a my brain moving to power-saving mode
         | and muting some of my anxiety / perfectionism tendencies. Does
         | this explanation resonate with you at all?
        
           | kurisufag wrote:
           | That's possible. It feels a lot like the placebo component in
           | drinking: if you're free to ignore one of the few things you
           | need to /live/, it should be much easier psychologically to
           | be carefree (similar to "oh, haha, i'm drunk, might as well
           | get wacky").
        
         | puzzlingcaptcha wrote:
         | It's not unusual to feel good after pulling an all-nighter.
         | Sleep is when re-uptake of serotonin takes place, so if you
         | interrupt it you end up with a surplus. Although there are also
         | other possible explanations [1]
         | 
         | 1. https://www.pnas.org/doi/10.1073/pnas.2214505120
        
           | taeric wrote:
           | I'm assuming it is similar to the "runners high" people get
           | at the end of a long run? You will feel very energized in
           | ways that don't make sense. And if you don't force yourself
           | to just lay down and pass out, you can keep going for longer
           | than you would have thought. Will crash harder, though, if my
           | experience is common.
        
         | rtaylorgarlock wrote:
         | Age sounds like a factor here. I know zero long-term healthy
         | ppl in 30s and beyond who act/think this way.
        
           | freedomben wrote:
           | Indeed, as a 20 year old I would stay up all night pretty
           | regularly for work and occasionally fun. At 40 I'm not sure I
           | would live through it, at least not in a cognitive state
           | where I could converse.
        
           | jtuple wrote:
           | I've done a few all-nighters in my 30s and 40s, and they
           | generally feel the same as my 20s. Still get that clear
           | headed, high focus second wind around 4am that carries
           | through until noon or so.
           | 
           | But, I definitely crash harder than I did in my 20s and need
           | longer to recover after. In my 20s, would be fine if the next
           | night was a normal one, now it takes multiple days.
           | 
           | It's definitely something I try to avoid at this age, as
           | opposed to just being standard procedure back in college.
        
         | boogieknite wrote:
         | anecdotally i feel pretty good when im buzzed but reality is my
         | performance is impaired. there is a teeter-totter of
         | overconfidence and impairment where the liquid confidence
         | actually helps more than the impairment impairs but its a sweet
         | spot
        
           | kurisufag wrote:
           | sleep deprivation definitely reduces raw reasoning ability.
           | in some cases, though (and this is true for getting buzzed as
           | well) the trade-off is absolutely productive.
        
       | cyberdrunk2 wrote:
       | I wonder if this could help explain why creatine helps mitigate
       | the effects of sleep deprivation. Since creatine aids in water
       | retention.
       | 
       | https://pubmed.ncbi.nlm.nih.gov/16416332/
        
         | layer8 wrote:
         | It's not clear how water retention would help with the needed
         | flushing.
        
           | regularfry wrote:
           | Hypothetically, more water retention would mean that the
           | fluid being flushed is less concentrated, and if the flushing
           | mechanism is triggered by a certain concentration level then
           | it'll happen less frequently.
           | 
           | Hard to imagine that it would be worth more than a few
           | percent though.
        
             | layer8 wrote:
             | Less flushing sounds like it would also worsen the sleep
             | deprivation, even if it reduces the momentary lapses.
        
         | jorvi wrote:
         | Mix your cheap instant coffee with creatine powder and ORS for
         | that ultimate early morning flavor bomb!
        
           | zer00eyz wrote:
           | The mechanism of creatine isn't that straight forward.
           | 
           | You need to take it for a while for it to build up, and for
           | water to accumulate in cells.
           | 
           | It would also be disgusting in a cup of coffee!
        
           | pawelduda wrote:
           | Don't forget to intensely shake your head after consumption
           | for a proper brain flush
        
           | huemaahn wrote:
           | Welp, now I'm bout to make the nastiest coffee known to man
           | for the next 3 months
        
         | Citizen8396 wrote:
         | I would imagine it has more to do with its principal function
         | in recycling ADP back to ATP (fuel for cells). People who are
         | sleep deprived also have impaired glucose metabolism, meaning
         | that the cellular "fuel pipeline" is impeded. Perhaps creatine
         | is especially helpful under these conditions.
         | 
         | https://pmc.ncbi.nlm.nih.gov/articles/PMC1991337/
        
       | earless1 wrote:
       | So biological garbage collection pauses then? skip sleep, and the
       | brain tries to run gc cycles during runtime. Causing attention
       | and performance latency spikes. Evolution wrote the original JVM.
        
         | layer8 wrote:
         | Luckily it doesn't clear all unreferenced memory, though.
        
           | DenisM wrote:
           | Cleanup is an LRU process.
           | 
           | Once a memory lapses you have to relearn from life experience
           | (or not at all).
        
             | thaumasiotes wrote:
             | No, a lapsed memory can be provoked. It doesn't have to be
             | relearned. It is "lapsed" because the organizational path
             | to it within your brain has been lost, like a book in a
             | library that has been left out of the card catalog, but
             | just like the book, if you happen to find it anyway, it
             | will be there.
             | 
             | Compare, from https://evolutionistx.wordpress.com/2016/12/1
             | 6/anthropology-... :
             | 
             | > at the first news of English ships in the area, Buckley
             | rushed to the spot. He attempted to make contact, but
             | couldn't swim out to the ship and couldn't convince the
             | ship to send a boat to him (Buckley had, at this point,
             | forgotten how to speak English.) Buckley was again
             | heartbroken until another ship showed up, and he found the
             | English colonists and tried to approach them:
             | 
             | > "Presently some of the natives saw me, and turning round,
             | pointed me out to one of the white people; and seeing they
             | had done so, I walked away from the well, up to their
             | place, and seated myself there, having my spears and other
             | war and hunting implements between my legs. The white men
             | could not make me out-my half-cast colour, and
             | extraordinary height and figure [Buckley was around 6'5" or
             | taller,]-dressed, or rather undressed, as I was-completely
             | confounding them as to my real character. At length one of
             | them came up and asked me some questions, which I could not
             | understand; but when he offered me bread-calling it by its
             | name-a cloud appeared to pass from over my brain, and I
             | soon repeated that, and other English words after him. ...
             | 
             | > "Word by word I began to comprehend what they said, and
             | soon understood, as if by instinct, that they intended to
             | remain in the country; that they had seen several of the
             | native chiefs, with whom-as they said-they had exchanged
             | all sorts of things for land; but that I knew could not
             | have been
             | 
             | I submit that it takes more than a day to learn English if
             | you don't already know it.
             | 
             | Once I was in a Toys-R-Us and noticed a cover image among
             | the bottom-of-the-barrel DVD display which caused me to put
             | what I was doing on hold for several minutes while I stared
             | at the DVD. I bought it, and it turned out to be a movie I
             | had watched many times when I was very young, but that
             | information hadn't been accessible to me.
        
           | jyounker wrote:
           | Are you sure about that?
        
           | bigbuppo wrote:
           | I forgot what I was going to type, but I didn't get enough
           | sleep last night.
        
           | blauditore wrote:
           | Fun fact: Suppressed/hidden/lost memories due to trauma that
           | appear to re-surface through therapy are not a real thing, as
           | previously thought (and still by some psychotherapists).
           | Nowadays it's understood by psychology that any memories "re-
           | surfacing" in therapy are in fact newly created, although the
           | patient themselves cannot tell the difference. Allegedly,
           | whole accusations of childhood abuse may have been created
           | out of thin air, without the victim realizing.
           | 
           | https://en.wikipedia.org/wiki/Recovered-memory_therapy (see
           | research section)
        
             | slater wrote:
             | Gonna need some citations on that "fun fact"
        
               | blauditore wrote:
               | https://en.wikipedia.org/wiki/Recovered-memory_therapy
               | (especially the research section)
        
               | svnt wrote:
               | That is extremely weak to nonexistent counter-evidence
               | that seems to focus on supporting Loftus, who has put a
               | lot of effort into the defense of her public persona. I
               | don't disagree that it is possible to manufacture
               | memories but the evidence isn't there to support your
               | conclusion or the converse.
        
               | Aurornis wrote:
               | Recovered-memory therapy (the topic of the Wikipedia
               | article) is very clearly quack science and has been
               | discredited.
               | 
               | Some of the techniques used in the therapy include giving
               | patients sedative-hypnotic drugs to put the patient in a
               | waking dream-like state while the therapist asks leading
               | questions to get them to "remember" an event. The same
               | drugs they used are known to be associated with false
               | memories, like when someone falsely recalls something
               | from a vivid dream as having actually happened.
        
               | svnt wrote:
               | It has fallen out of favor based on a lack of evidential
               | support, for sure. It has not really been dismantled
               | publicly scientifically, but mostly quietly, perhaps in
               | order to protect its practitioners, perhaps because the
               | research cannot currently be ethically conducted.
               | 
               | I am not advocating for it, just stating the near total
               | lack of substantive scientific evidence presented either
               | in support or opposed.
        
               | ghurtado wrote:
               | Claim: "modern cancer research is a scam"
               | 
               | Proof: "colloidal silver has been used to attempt to cure
               | cancer".
               | 
               | Solid logic.
        
               | ghurtado wrote:
               | People downvoting a request for supporting evidence is
               | peak Hacker News.
        
               | fsckboy wrote:
               | people demanding supporting evidence without expending
               | any effort themselves is peak internet.
        
               | jjk166 wrote:
               | The onus of proof lies on those making a claim. If you're
               | unwilling to back up what you say, don't say it.
        
               | nwienert wrote:
               | In science. On a casual forum you have no obligation and
               | I'd rather someone leave a short comment so I at least
               | know, if I'm interested I'll go look and verify myself.
        
               | theshackleford wrote:
               | It's not my job to track down proof only every bullshit
               | claim thrown at me.
        
             | layer8 wrote:
             | People can remember things that hadn't re-entered their
             | mind for decades. It certainly happened to me a number of
             | times (completely trauma-unrelated and not actively
             | elicited).
        
               | worldsayshi wrote:
               | My guess is that long term memory recovery is inherently
               | a reconstruction from the pieces that you have retained.
               | So it is not unlikely to include dreamed up parts.
        
               | layer8 wrote:
               | The accuracy of recollection can certainly vary, but the
               | point is that _some_ information is retained long-term
               | even when it isn't made use of in the meantime. Of course
               | one could argue that actually it is being made use of
               | unconsciously, but I'm skeptical of that, given the
               | relative irrelevance of the details that can be
               | recollected. It's also not that difficult to imagine that
               | some memory-representing micro-structures in the brain
               | just happen to be stable over decades even when they
               | remain untapped.
        
               | Aurornis wrote:
               | The debunked recovered memory therapy was something
               | different: They would use different techniques and
               | leading questions to try to get a patient to think they
               | remembered something that may not have happened at all.
               | 
               | Some of the techniques included hypnosis or even giving
               | the patients (including children) sedative-hypnotic drugs
               | before pressuring them with the leading questions.
               | 
               | If they could eventually get the person or child to claim
               | to have some memory of the event (after asking a lot of
               | leading questions and maybe even drugging them) they
               | considered it to be a recovery of the memory.
        
               | bpj wrote:
               | This has been my experience as someone who has
               | experienced childhood trauma, and what I've inferred from
               | my therapist. He taught me that the memories I have are
               | typically exaggerations of what happened and it's hard to
               | pin down what truly happened. The only evidence I have
               | that has any merit is my siblings can corroborate with
               | similar experiences since it happened to all of us, and
               | I'm sensitive to things related to these traumas. Almost
               | every day I can feel the things that happened, and on my
               | worst days these areas are much more sensitive.
               | 
               | On top of that, I have legitimate memories that were not
               | traumatic, but still related to the same traumas because
               | said person attempted to encourage these activities
               | throughout my young life on rare occasions. I didn't
               | remember what happened as a kid, but I knew something
               | wasn't right and I wasn't comfortable. It wasn't until I
               | was almost 30 that I had my first "flashback" which was a
               | fractured memory, I still remember it looked like a faded
               | photograph in my mind, and it was accompanied by an
               | extremely uncomfortable feeling.
               | 
               | The re-surfacing memories aren't real in a sense, but in
               | my case they aren't entirely fake either.
               | 
               | I wonder if it's possible that things can be completely
               | imagined with absolutely no basis what-so-ever in certain
               | circumstances, and I also wonder how difficult it is to
               | discern that. It seems to be a difficult concept to
               | manage.
        
               | warmedcookie wrote:
               | Indeed. I was browsing a Nintendo fan site I made in 1998
               | on archive.org when I was just 11 years old. I don't
               | remember every detail about making it, but my brain had
               | no problem stitching all the pieces it did retain back
               | together.
               | 
               | On the other hand, I do have some Gandalf "I have no
               | memory of this place" moments for other things.
        
               | Aurornis wrote:
               | A valid memory spontaneously re-entering your mind is
               | different.
               | 
               | The idea of "repressed memories" was that people had
               | hidden memories that they couldn't access, even if they
               | tried. According to the theory, even if someone brought
               | up the past event and tried to remind the person about
               | it, they would be unable to recall it happening because
               | their brain had blocked it out.
               | 
               | The idea was that only intervention by a therapist or
               | some other special event could help the person "unlock"
               | the repressed memories, making them available for
               | remembering again.
               | 
               | What was really happening was that some therapists were
               | leading people into "remembering" things that didn't
               | happen through aggressive prompting and pushing, much
               | like what happens when an aggressive investigator
               | convinces a vulnerable person to falsely confess to
               | something they didn't do.
        
               | tehjoker wrote:
               | I wouldn't be surprised if there are inaccessible, partly
               | corrupted memories encoded in the hippocampus. I suspect
               | most of them cannot be prompted by a therapist though,
               | and likely there is no practical way to recover them.
        
               | strbean wrote:
               | I think it's all a matter of finding a trigger (or
               | reference) to grab the memory. A therapist talking to you
               | almost certainly wouldn't achieve that, but walking down
               | the street and smelling an odd smell might.
        
               | tehjoker wrote:
               | I think it depends on the stage of degradation and
               | whether the network is still connected to something that
               | can interpret it.
        
               | rkhassen9 wrote:
               | I once found a recording of a lab session in high school
               | physics. A day I completely forgot about. A moment that
               | had no bookmarks in my brain.
               | 
               | Other things about that day were surfaced. How my braces
               | felt and the fear I felt about forgetting a textbook.
               | 
               | All real, but unsurfaced until then.
        
               | t0mas88 wrote:
               | That makes sense considering that human memory is
               | strongly based on associations. Activating nearby
               | memories can bring things back.
               | 
               | If you hear the first tones or words of a song you're
               | much more likely to be able to tell the lyrics that
               | follow compared to being asked to say those lyrics based
               | on the title.
        
               | kulahan wrote:
               | They won't remember it accurately anyways, so it's kind
               | of a moot point.
               | 
               | Though you're right - a specific scent can easily call up
               | an ancient, forgotten memory.
        
               | GuB-42 wrote:
               | This is a more precise statement than just "you can
               | recall things you thought you forgot".
               | 
               | It is specifically about trauma, and generally you don't
               | forget traumatic events and that's often a big part of
               | the problem. We are not talking about trivial things like
               | the name of your maths teacher in high school, which have
               | a tendency to come and go.
               | 
               | It is also specifically about therapy, that is an
               | environment where you are actively encouraged to recall
               | memories. We know how easy it is to make up memories,
               | especially with the help of a third party (here, the
               | therapist).
               | 
               | Combine the two: memories that are hard to forget and an
               | environment conductive to making false memories and it
               | becomes very likely that the "lost" memories are
               | completely made up.
        
               | theshackleford wrote:
               | > and generally you don't forget traumatic events
               | 
               | That depends on how many you endured really. Only so much
               | room in the old noggin with everything else important
               | going on.
        
               | Muromec wrote:
               | >It is specifically about trauma, and generally you don't
               | forget traumatic events and that's often a big part of
               | the problem.
               | 
               | Oh, of course you can.
        
             | anal_reactor wrote:
             | Most people think that when their memory fails it's just
             | the act of not remembering something, but misremembering
             | something happens equally often, and completely making up
             | shit also does happen. It's just like LLM hallucinations.
        
             | bollocks9 wrote:
             | What about Dr. Jim Tucker's two child psych cases, James
             | Leininger and Ryan Hammons?
             | 
             | One remembered memories of a WWII pilot named James Huston
             | Jr. and the other a deceased Hollywood agent named Marty
             | Martyn.
             | 
             | Putting aside the reincarnation hypothesis for the moment,
             | do you think the kids invented the details and
             | coincidentally happened to match to a real person or were
             | they fully coached? Maybe they didn't get enough sleep or
             | got too much sleep?
        
             | elmomle wrote:
             | The statement "there is evidence of black swans" does not
             | justify the conclusion "every swan is black".
        
               | fsckboy wrote:
               | if you specialize in looking for black swans, and you've
               | looked for more black swans than anybody ever, and all
               | the black swans you thought you'd found have turned out
               | to be sooty white swans, people might be interested in
               | reading about your experience and have their faith shaken
               | that black swans actually exist.
               | 
               | I'm reminded of the story of dragon sightings in Great
               | Britain: after the printing press and newspapers and
               | newspaper reporters chasing stories emerged, as news
               | distribution out from city centers into rural areas
               | increased, it seems dragons picked up and moved farther
               | away, only being spotted in the hinterlands without news.
               | 
               | You apparently would keep your mind open to the idea that
               | dragons don't like the smell of newsprint as no other
               | conclusion could be more plausible sheerly on the basis
               | of logic?
        
             | ghurtado wrote:
             | > any memories "re-surfacing" in therapy are in fact newly
             | created,
             | 
             | You're saying that those memories are exactly the same as
             | all the other memories.
             | 
             | Every time you "recall" something, you are not pulling up
             | some file that is always the same. You are actively
             | recreating the memory.
             | 
             | There's nothing "fun" or insightful about this, this
             | mechanism has been known for a long time.
             | 
             | Obviously it's not unique to psychotherapy.
             | 
             | > may have been created
             | 
             | Most things that "may" have happened do not warrant
             | absolute statements such as "that's not a thing" (which,
             | incidentally, is a particularly empty statement in any
             | context, since every _thing_ is a thing)
        
             | DiscourseFan wrote:
             | There are two types of repression, however. The notion that
             | primarily repressed memories--say, those of being
             | breastfed, of being potty trained--could ever resurface is
             | bogus of course. But it is that original violence, first of
             | being cared for, and then having that care taken away and
             | even, in many cases, transforming into authoritarian
             | violence in order to be socialized properly, that
             | precipitates all other "secondary" repressions like
             | Freudian slips, even screen memories or rationalizations.
             | No, most people traumatized past the age of say, 5, won't
             | readily forget it. But perhaps they will have a way of
             | reconciling with that trauma in an unhealthy or not fully
             | conscious manner (consider self-harming, or drug abuse,
             | making up a narrative in order to stay with a partner who
             | violently abuses them). And they will not readily connect
             | their traumatic experiences with their unhealthy coping
             | mechanisms. And we could say that the connection between
             | unconscious behaviors and trauma, when revealed, could be
             | considered a "re-surfacing." Even if I can't remember being
             | breastfed, I know that I find the warm embrace of another's
             | arm's comforting and soothing, and this perhaps relates to
             | my original state of relaxation as a child in my mother's
             | arms, for instance.
        
               | drdeca wrote:
               | Why would it relate to your past experience of being held
               | in your mothers arms, rather than to whatever inbuilt
               | tendencies that lead one to respond well to being held in
               | one's mother's arms while a baby?
               | 
               | Like, if kissing is derived from impulses relating to
               | breastfeeding (which is a hypothesis that, AIUI, is in
               | good standing, though not the only one in good standing
               | nor necessarily more favored than a couple others), I
               | wouldn't think that therefore someone who was only ever
               | bottle-fed as a baby would therefore not get anything out
               | of kissing. The appeal of "my lips on another person"
               | should be there regardless, just as it was for the first
               | time a baby is breastfed (though, of course, it is also a
               | cultural thing: not all cultures have had kissing as a
               | standardized way of expressing affection, so whether one
               | grows up in a context where kissing plays a role, that
               | probably also plays a part in whether one finds it
               | appealing to have one's lips on another person).
        
             | dbspin wrote:
             | The problem is not that memories can't be repressed.
             | There's plenty of research demonstrating repression does
             | exist as a defence mechanism. The problem is that even
             | highly evocative memories can also relatively easily be
             | falsified, or modified through elicitation and reframing.
             | Since there's no neurological stenographer, there is no
             | mechanism even in principle to identify the difference
             | between the two. With potential consequences like the
             | satanic panic of recovered and elicited memories of sexual
             | abuse. That's what Elizabeth Loftus and others have shown,
             | and shown so thoroughly that eye witness testimony should
             | never be trusted.
        
               | saltcured wrote:
               | As a counterpoint to this, I am replying here because I
               | can't make myself write a polite response to the GPP.
               | 
               | Yes, witness testimony is always potentially flawed.
               | 
               | But knowing "some repressed memory recovery is false"
               | does not justify saying that repressed memories are not a
               | real thing. Repressed memories do happen. They do come
               | back sometimes. When they do, they are just as valid as
               | any normal memory that a person thinks they always had.
               | 
               | I know because I had them myself. Mine were of trauma in
               | the age range from 5-9. I had a high "ACE score" when I
               | eventually looked into this. I did not have any therapy
               | session prompting the recall, I just remembered them
               | spontaneously around age 15 when I was empathizing with a
               | schoolmate who told me about domestic violence. It was a
               | sickening feeling to have this whole phase of my past
               | come unlocked.
               | 
               | Amazingly, it submerged into repression again. I next
               | remembered it at about age 20. In between, I had years of
               | basically not remembering/knowing that I had any of this
               | trauma or that I had experience the earlier recall. They
               | all came back together, again triggered by an empathetic
               | moment in college. Again it was disorienting to have this
               | whole aspect of my past reopen.
               | 
               | At that later point, I confronted people who were around
               | my childhood and got enough of a painful discussion,
               | confession, and apology to know that these memories were
               | not invented.
               | 
               | I had other forms of childhood trauma that never
               | submerged. I don't know why this one section did.
               | 
               | I find it very offensive for someone to make broad
               | statements that these phenomena do not exist.
        
               | eiginn wrote:
               | This mirrors my experience as well of multiple instances
               | over my life of repressing childhood trauma and some
               | event or conversation suddenly bringing it back to the
               | surface.
        
               | jimmaswell wrote:
               | Not to minimize your experience or anything like that,
               | I'm just thinking out loud: What's typically the
               | delineation between repressed and "not on the mind at the
               | moment"? We naturally "forget" things all the time
               | because there's no need for them to be in our current
               | context window, e.g. I can't recite every coffee shop
               | I've been to, but maybe if you start talking about a
               | coffee shop with uncomfortable seats, I'll remember the
               | one I went to with uncomfortable seats. Not a comparable
               | experience in general of course, but one wouldn't say I
               | repressed the coffee shop. Is it more like if I started
               | at "uncomfortable coffee shop", nothing came to mind, but
               | then I later remembered only after smelling some special
               | flavor of coffee beans they had had?
        
               | mrsvanwinkle wrote:
               | I can objectively say your reply minimizes the previous
               | two posts who shared childhood traumas by the objective
               | fact that you are implying (if they are not able to
               | satisfy your Scientific Endeavor) that, if there is no
               | delineation, then their repression of childhood trauma is
               | equivalent and minimized or perhaps exalted if coffee is
               | your religion to the repression of your religious
               | experience of this coffee shop. If you were perhaps a
               | child victim in this coffee shop maybe? You literally
               | erased the trauma part. That is the delineation if you
               | still need to think about this out loud
        
               | saltcured wrote:
               | A repressed memory and its associated knowledge and
               | entailment is "not there" until triggered properly. To
               | the extent that our autobiographical memories construct
               | our sense of identity, repressed memories have been
               | censored from ourselves. And, I think it is censored for
               | a purpose, not because it was one too many bits of trivia
               | to keep in ready memory. I think it is a coping mechanism
               | like very deep and targeted denial or dissociation.
               | 
               | When such memories come back, it can be like a mini
               | identity crisis. You suddenly know things that are
               | counter to your self-identity from the moment before.
               | Once I was able to absorb the whole picture and not
               | recoil back into repression, it became a permanent and
               | unpleasant part of my self. .
               | 
               | There can be flashbacks of related events, some of which
               | I also might feel are remembered for the first time in a
               | long time. Those little flashbacks might be like
               | remembering your specific uncomfortable cafe. The overall
               | memory recovery is like suddenly realizing I spent years
               | in a theater of war, that happened to have such cafes in
               | it.
        
               | mrsvanwinkle wrote:
               | Thank you so much, the parent thread was truly an
               | uncomfortably disturbing read and your post is a
               | necessary contrast to "rational" "objective" "minds"
               | armchairing something so delicate with gross finality.
        
               | oceanplexian wrote:
               | You might "think" you had a repressed memory but it could
               | all be completely made up. You might even get other
               | people to believe it, because human memory is incredibly
               | faulty. Shared delusions are literally a "known bug" of
               | human biology. Wikipedia has a whole page on them
               | (https://en.wikipedia.org/wiki/Folie_%C3%A0_deux). The
               | Seattle Windshield Pitting Epidemic (https://en.wikipedia
               | .org/wiki/Seattle_windshield_pitting_epi...) is yet
               | another example
               | 
               | The thing that changed though is since the 2010s everyone
               | has a high definition camera in their pocket. Everything
               | you do is recorded online. Kids that grew up in the last
               | few years will have their entire childhood recorded in
               | some way or another. Every movement tracked by GPS.
               | Therefore, while I don't agree completely, I wouldn't be
               | surprised if some assumptions about psychology are
               | upended and a great deal of so called repressed memories
               | turn out to be bogus when we can easily disprove them.
        
               | saltcured wrote:
               | Malicious suppression and gas-lighting are also known
               | functions of human biology.
               | 
               | Yes, real life is messy and ideals like justice are quite
               | difficult or impossible to achieve.
               | 
               | Don't assume you can cleverly deduce a nice, absolute and
               | comfortable answer. That's just another coping mechanism
               | called rationalization.
        
               | JohnMakin wrote:
               | The person you're responding to said they did the work of
               | verifying themselves with third parties. Do you not
               | believe that too? People dont suddenly just admit to
               | committing severe abuse because they were convinced to do
               | so. In fact, usually the opposite happens with abusers -
               | they delude themselves into thinking the abuse never
               | happened and believe/defend this very aggressively.
               | 
               | This whole thread is gross. I'd say you should be ashamed
               | of yourself but you likely lack the prerequisite self
               | inspection.
        
               | JohnMakin wrote:
               | Thanks so much. I was wanting to write a scathing
               | response as well but you calmly explained what I wanted
               | to. I had severe childhood abuse that was documented by
               | third parties I'd completely forgotten about - when I
               | remembered them in therapy, my therapist thought they
               | were fake or delusional too and sorta gaslit me about it.
               | I had to go hunt down the receipts, which for me was
               | traumatic in and of itself and permanently severed a few
               | relationships with my family members, which didn't have
               | to happen. I fired her over it.
               | 
               | The comments in this thread are indeed disturbing.
               | Clearly many on this forum have led blessed lives and
               | can't imagine people having it differently,
        
             | pcthrowaway wrote:
             | Sure it's a real thing for memories to surface that were
             | previously buried. It's happened to me.
             | 
             | If it happens in therapy, that doesn't mean the memories
             | are "implanted". And not all memories lack the ability to
             | validate them... for example, if you've forgotten someone's
             | name, then remember it later, you can call out to them by
             | their name to confirm that you've correctly remembered it.
             | 
             | Memories tumble around in the brain all the time, not all
             | memories are easy to access, but that doesn't mean they're
             | inaccessible.
             | 
             | The point that memories can _also_ be implanted or
             | fabricated during therapy is absolutely an important one,
             | but dismissing the possibility for memories to resurface
             | (and conflating any situation where this might happen with
             | a specific type of discredited therapy) is needlessly
             | reductive.
        
             | agumonkey wrote:
             | I beg to differ, or at least I'd need clarification, some
             | people experience traumatic visions from what is assumed
             | repressed memories (with or without therapy)
             | 
             | It might be something that one might not understand if
             | he/she doesn't live through it I guess
        
             | bozhark wrote:
             | Careful with this absolute assumption. The brain
             | rationalizes. Though irrationally.
             | 
             | Sometimes yes, created to validate, sometimes no, unlearns
             | to disassociate
        
             | layman51 wrote:
             | This idea of unconscious memories perhaps being a type of
             | fantasy is also discussed in this article too:
             | 
             | https://en.wikipedia.org/wiki/Freud%27s_seduction_theory
        
           | ghurtado wrote:
           | I realize you're making a joke, but there is no such thing as
           | "unreferenced memories", as in, something that is no longer
           | in use and has been removed from the brain.
           | 
           | Every memory your brain has ever produced is still there,
           | even if most are beyond conscious access. Memories quite
           | literally become a permanent part of you.
           | 
           | A lot of people mistakenly think of human memory as a sort of
           | hard drive with limited capacity, with files being deleted to
           | make room for new ones. It's very much not like that.
        
             | pdonis wrote:
             | If you are implying that human memory has infinite
             | capacity, that's not possible. The human brain is a finite,
             | physical thing. It can't store an infinite amount of data.
             | 
             | If you just mean that human memory has a finite capacity
             | that's much larger than anyone has come close to reaching
             | by storing the memories of a normal human lifetime, that
             | might make sense.
             | 
             | Do you have any references for your statements about
             | memory? I'm not familiar with whatever science there is in
             | this area.
        
               | ghurtado wrote:
               | I didn't mean either of the things that you are wondering
               | whether I meant, so i can't give you evidence of those
               | things you made up yourself.
               | 
               | If you have questions about my comment, I'm happy to try
               | to explain myself better
               | 
               | "I didn't understand you at all, so you must have meant
               | either A or B" is not the way to reach an understanding
        
               | vanviegen wrote:
               | Your words: "Every memory your brain has ever produced is
               | still there [..]"
               | 
               | How would that _not_ imply infinite storage?
        
               | dragonwriter wrote:
               | It wouldn't imply infinite storage because human life is
               | not infinite in time and memories do not accumulate at an
               | infinite rate in storage consumed per unit time, so the
               | total storage over a human lifespan is finite, so the
               | claim can be true with finite storage.
               | 
               | It is almost certainly false, but it doesn't require
               | infinite storage to be true.
        
               | pdonis wrote:
               | _> human life is not infinite in time and memories do not
               | accumulate at an infinite rate in storage consumed per
               | unit time_
               | 
               | Which would put it into the category of the second part
               | of my comment--which the person I was responding to said
               | was not relevant to what they meant.
        
               | pdonis wrote:
               | _> i can 't give you evidence of those things you made up
               | yourself._
               | 
               | I didn't ask for that. I asked if you have references for
               | what _you_ said. Even if I misunderstood you, that
               | shouldn 't be a reason for you not to give references for
               | _your_ statements, if you have them.
               | 
               | If you don't have any references to back up _your_
               | statements, then I 'm not sure what you're basing them
               | on.
        
               | standardly wrote:
               | > The human brain is a finite, physical thing. It can't
               | store an infinite amount of data.
               | 
               | True, but it doesn't really detract from his statement
               | because do we really know what that upper bound even is?
               | I don't think we come close to the theoretical storage
               | limit... So saying "every memory you have is permanently
               | stored" is effectively true, at least true enough for a
               | thought experiment like this. Perhaps when people live to
               | be 200 years old and we know more about the brain we can
               | test this, though.
               | 
               | I used to be weary of learning new, complex things,
               | thinking I'd "lose" old knowledge XD
        
               | pdonis wrote:
               | _> I don 't think we come close to the theoretical
               | storage limit_
               | 
               | That was the point of the second part of my comment--
               | which the person I was responding to said was not
               | relevant to what he meant.
        
               | jjk166 wrote:
               | The claim that everything is there does not imply
               | infinite, or even large capacity.
               | 
               | Consider an exponentially weighted moving average - you
               | can just keep putting more data in forever and the memory
               | requirement is constant.
               | 
               | The brain stores information as a weighted graph which
               | basically acts as lossy compression. When you gain more
               | information, graph weights are updated, essentially
               | compressing what was already in there further. Eventually
               | you get to a point where what you can recall is useless,
               | which is what we would consider forgotten, and eventually
               | the contribution of a single datapoint becomes
               | insignificant, but it never reaches zero.
        
               | pdonis wrote:
               | _> The claim that everything is there does not imply
               | infinite, or even large capacity._
               | 
               | It implies enough capacity to store everything. But what
               | you describe is _not_ storing everything.
               | 
               |  _> lossy compression_
               | 
               | Which means you're _not_ storing all the information. You
               | 're not storing everything.
               | 
               |  _> When you gain more information, graph weights are
               | updated, essentially compressing what was already in
               | there further._
               | 
               | In other words, each time you store a new memory, you
               | throw some old information away.
               | 
               | Which the person I was responding to said does _not_
               | happen.
        
             | mym1990 wrote:
             | Knowing almost nothing about memory and the brain, I don't
             | know if I agree with "Every memory your brain has ever
             | produced is still there".
             | 
             | Memories seem to be constructed by a group of neurons
             | together, and it seems clear that neurodegeneration is a
             | thing, whether by trauma or due to aging. When pathways
             | degenerate, maybe you have a partial memory that you brain
             | can help fill the gaps with(and often incorrectly), but
             | that does not make it the original memory.
        
             | vanviegen wrote:
             | Bullocks. Memories fade. Or do you really believe that
             | 'subconsciously' I still know what I had for dinner today
             | exactly 30 years ago?
             | 
             | The way I understand it, it's just that, unlike on disk,
             | the deletion process is not binary. Weak connections that
             | are not revisited regularly gradually become weaker, until
             | they're undistinguishable from noise (false memories).
        
             | lux_sprwhk wrote:
             | I had this experience at Big Bend State park that makes me
             | think they are. I didn't bring enough water and camped in
             | the primitive area. At night, I was dehydrated pretty bad.
             | When I finally got a little sleep (it was tough to say the
             | least), I had this vivid dream where I put a pebble in my
             | mouth and started sucking on it to make saliva. Then I woke
             | up for real, and I knew it because there was a lot of wind
             | IRL, that wasn't in the dream. So I took out a coin from my
             | back, put it in my mouth to make saliva, and got a little
             | bit of relief. Enough for a couple hours until it was dawn,
             | and had enough light to hike down to the restroom area.
             | 
             | I don't know where I got this trick. Likely some survival
             | show or some novel. But I don't have any background in
             | survival, otherwise, I would have brought a lot more water.
             | 
             | So my brain knew there was a memory that could help and
             | made up a dream about it is my theory.
        
         | Zenul_Abidin wrote:
         | Is Sun Microsystems in the room with us?
        
         | dathinab wrote:
         | this might explain how "power napping" (<30min) can help so
         | much when you are sleep deprived even through it's too short to
         | really count as sleep. I wonder if you can find that when sleep
         | deprived people power nap a "flush" happens then
        
           | hinkley wrote:
           | There's a phenomenon we have known about since at least the
           | late 1980s when Race Across America riders were using it.
           | 
           | Essentially these guys try to stay up for the first few days
           | and then sleep less than 8 hours after that. Way less. Many
           | of them end up hallucinating by the end, and only their
           | extreme fitness levels probably save them from just dying
           | from lack of sleep.
           | 
           | The trick is that waking up to daylight makes you feel more
           | rested. So the teams would have their riders sleep 2-3 hours
           | from just before dawn until dawn so they would wake up to
           | sunlight. Physiologically the difference is small, but
           | psychologically it's much bigger.
           | 
           | Some of the effect of power napping is likely the same sort
           | of trickery, just as caffeine is partly trickery and partly
           | adrenal.
        
         | hinkley wrote:
         | Skip enough sleep and parts of your brain will try to nap while
         | you're doing things like meetings.
        
           | timeinput wrote:
           | Depending on the meeting it might be worth a nap even if I'm
           | well rested.
        
       | thimkerbell wrote:
       | [This is one of those article titles that would really benefit
       | from adding one more word.]
        
         | cvoss wrote:
         | Or some parentheses. Is "due to" naturally left-associative or
         | right-associative? I would have said 'right', which gives the
         | unintended reading of the sentence.
         | 
         | Attention lapses due to (sleep deprivation due to flushing
         | fluid from brain).
         | 
         | (Attention lapses due to sleep deprivation) due to flushing
         | fluid from brain.
        
       | shahbaby wrote:
       | > For example, what you don't want to do is NOT take amphetamines
       | at testing if you had used them to study;
       | 
       | Hard disagree there. If you get any anxiety during the test it's
       | better to take it only while studying.
        
         | lazide wrote:
         | Huh? Care to explain?
        
         | 85392_school wrote:
         | Did you mean to reply to
         | <https://news.ycombinator.com/item?id=45772306>?
        
       | epsilonic wrote:
       | Exogenous ketones (such as BHB salts) are known to help with
       | glymphatic drainage in the brain during sleep. I've used them
       | extensively and have noticed improved sleep with nearly a
       | doubling of the time spent in REM stage.
        
         | smith7018 wrote:
         | Could you go into detail what you take, how much, and when? I
         | could always use a little boost for my sleep!
        
           | epsilonic wrote:
           | Sure. When I have a night of poor sleep or anticipate one, I
           | usually take 6 grams of BHB salts in the morning on an empty
           | stomach. You can work your way up to a maximum of 12 grams,
           | but I would advise caution since it can cause diarrhea. I
           | would start by buying the cheapest product (nutricost) you
           | can find online; if it costs more than $80 for ~300g, then
           | you're probably getting ripped off. I noticed that I have
           | very lucid dreams and experience strong hypnagogic jerks when
           | I take this supplement.
           | 
           | Here is some literature that I've perused to support my
           | experimentation with BHB salts:
           | 
           | 1. b-hydroxybutyrate is a metabolic regulator of proteostasis
           | in the aged and Alzheimer disease brain (https://www.scienced
           | irect.com/science/article/pii/S245194562...)
           | 
           | 2. Refueling the post COVID-19 brain: potential role of
           | ketogenic medium chain triglyceride supplementation: an
           | hypothesis (https://www.frontiersin.org/journals/nutrition/ar
           | ticles/10.3...)
           | 
           | My motivation for pursuing this was protracted sleep
           | disturbance from long-covid.
        
       | 0xbadcafebee wrote:
       | So... can we trigger it manually? I'd love to be able to lay down
       | and press the 'flush brain' button.
        
         | vrx-meta wrote:
         | Research on NDSR, I have been using this for days I had to wake
         | up without proper rest.
         | 
         | If you have 15m, search this on YT for a guided practice and
         | test it yourself.
        
           | BobaFloutist wrote:
           | I believe you were referring to NSDR (Non-Sleep Deep Rest)?
        
             | Muromec wrote:
             | Mixing up acronyms is on brand with sleep deprivation.
        
           | GavinMcG wrote:
           | NSDR, rather--Non-Sleep Deep Rest.
        
           | niwtsol wrote:
           | Kind of related, but there is a concept of polyphasic sleep -
           | where you sleep for small increments throughout the day (like
           | 30 minutes every 3 hours). I did it for a bit at a startup
           | thinking we were "hacking sleep" and "getting more productive
           | hours out of every day!" - It takes awhile to transition to
           | it, but once there, your scheduled "sleeps" are insane, 15
           | minutes, feel like straight to REM. The main problem was if
           | you missed on schedule sleep you were a zombie.
        
             | tetha wrote:
             | Yeah, when I was looking into the plausibility and function
             | of polyphasic sleep, I stumbled across studies from the US
             | Airforce. Their conclusion was similar: In a controlled
             | enviroment, it can be spectacular and work really, really
             | well.
             | 
             | However, it is very, very fragile to any kind of
             | interruption, so they stopped looking into it.
        
             | cestith wrote:
             | When I worked an overnight shift and lived alone, I got
             | into a pattern of 2 to 3 hours a go three times a day.
             | These were after work, halfway or so through my personal
             | time, and before work. I used these separate times in
             | between sleeps for work, almost exclusively for chores, and
             | a dedicated slot for hobbies. I started each one refreshed,
             | which was great. It doesn't necessarily work so well when
             | aligning your life with a partner.
        
         | pbhjpbhj wrote:
         | Searching back, as I recall a video that was supposed to cause
         | [increased] CSF flow, I did find this -
         | https://news.ycombinator.com/item?id=34764730 about suggestions
         | some learning difficulties might be due to interrupted CSF
         | fluid flow.
         | 
         | The video (?) was related to clearing of plaques from the brain
         | with a view to mitigating Alzheimer's effects.
         | 
         | It was not the NSDR (Non-Sleep Deep Rest) videos a sibling
         | commenter posted.
        
           | krackers wrote:
           | https://news.ycombinator.com/item?id=41942775
        
         | g-b-r wrote:
         | If you're very tired you should be able to fall asleep, or at
         | least doze off, whenever you let yourself go.
         | 
         | It seems likely that you'll get those flushes right after
         | falling asleep, so a nap of a few minutes could help a lot.
         | 
         | In my experience, after a night without sleep even a 30 seconds
         | nap reinvigorates you significantly.
        
       | bzmrgonz wrote:
       | hmm.. this is interesting... the article says "spinal fluid exits
       | the cerebrospinal fluid (csf) flows out of the brain... I wonder
       | where it discharges these waste products. I ask because it is
       | believed we have a sort of chimney on our backs. I think I read
       | this on the article of the Irish lady who could detect alzheimers
       | years before any modern medical detection systems. But maybe it
       | is discharged in the gut? via the mesentery, the new organ they
       | finally named fo rthe stuff that holds our intestines together.
       | If anyone knows where it is discharged, please comment, I'm
       | interested in this, because I do prolong waterfasts every 3
       | months, and I strongly believe the brain drains waste into my
       | mouth during that time, because the taste in my mouth is
       | godawful, but if there are other exit points the brain discharges
       | waste, we probably need to know about them.
        
         | kingkawn wrote:
         | The description of the mesentery as a single organ dates to the
         | time of Da Vinci, at the latest.
        
         | canadiantim wrote:
         | I believe it's discharged basically half directly into the
         | venous system in the neck, the other half goes through the
         | lymphatic/glymphatic system and ultimately also the venous
         | system in the neck. That being said, that's just based on our
         | very crude understandings and I'm sure there are other
         | pathways.
        
         | jp57 wrote:
         | Why do you think that the taste in your mouth is waste draining
         | from your brain and not the result of some metabolic changes in
         | your body from the fast? Ketosis is known to cause a metallic
         | taste in the mouth, for example.
        
         | alfonsodev wrote:
         | What I understood from youtube gurus, take it with a grain of
         | salt, is that your brain is taking ketones as source of energy
         | to preserve the little glucose that goes into the system, and
         | as result it consumes less oxygen.
         | 
         | But I'm not sure the mouth taste comes from the brain's waste.
         | 
         | To some degree, if you had your brain inflamed by bad eating
         | habits, fasting would revert that and make the flushing more
         | efficient as well.
         | 
         | Again please take with with double grain of salt, since I don't
         | even know inflame brain is a thing for sure, or the correct
         | term.
        
       | pstuart wrote:
       | My pet theory is that dreams are the brain booting up/shutting
       | down and the equivalent of old analog TVs that have the flash of
       | static and bloom/collapse on the screen when turning off/on.
        
       | gwbas1c wrote:
       | Sometimes when I get a really bad migraine and poor sleep
       | together, I can literally feel a flushing feeling in my head once
       | I can fall asleep.
        
       | cozzyd wrote:
       | As a chronic undersleeper, good thing I don't drive!
        
       | codethief wrote:
       | > The scientists found that during these lapses, a wave of
       | cerebrospinal fluid (CSF) flows out of the brain
       | 
       | > Lewis and colleagues showed that CSF flow during sleep follows
       | a rhythmic pattern in and out of the brain
       | 
       | > Most significantly, they found a flux of CSF out of the brain
       | just as those lapses occurred. After each lapse, CSF flowed back
       | into the brain.
       | 
       | I can't believe the authors of the article didn't address one of
       | the most obvious questions: Where does the CSF flow to and where
       | does it flow back from? It's not like there are pipes leading out
       | of the brain, or the CSF will just leave my brain through my ears
       | or anything, will it?1 What happens with the waste products? (1
       | Though it would be kinda funny if this was where snot comes
       | from.)
       | 
       | EDIT: Wikipedia's got the answer:
       | 
       | > Clearing waste: CSF allows for the removal of waste products
       | from the brain,[3] and is critical in the brain's lymphatic
       | system, called the glymphatic system. Metabolic waste products
       | diffuse rapidly into CSF and are removed into the bloodstream as
       | CSF is absorbed. When this goes awry, CSF can become toxic [...]
       | 
       | https://en.wikipedia.org/wiki/Cerebrospinal_fluid
        
         | svnt wrote:
         | They didn't put it in there because knowing the flow of CSF is
         | so elemental to performing research in the field that it would
         | be a waste of everyone's time.
        
           | codethief wrote:
           | This is a pop sci article, though?
        
         | dragonwriter wrote:
         | > It's not like there are pipes leading out of the brain
         | 
         | There are, in fact, "pipes" leading out of the brain.
         | Cerebrospinal fluid is (and this is probably somewhat
         | oversimplified) produced from material in the bloodstream in
         | the ventricles in the brain, flows through the system of
         | ventricles and then out of the brain into the subarachnoid
         | space around the brain and spinal cord, and is then reabsorbed
         | into the bloodstream.
        
           | cvoss wrote:
           | And some people literally need an actual pipe implanted to
           | assist with CSF drainage.
           | 
           | https://www.mayoclinic.org/tests-procedures/brain-
           | shunt/abou...
        
       | rickcarlino wrote:
       | Could this be why SNRIs help some patients mitigate ADHD
       | symptoms?
        
       | JumpCrisscross wrote:
       | Could ADHD be caused by a broken flushing response? Lots of
       | flushing followed by intense focus caused by the _tabula rasa_?
        
         | delecti wrote:
         | I'm not an expert, but that wouldn't really fit with my
         | understanding of ADHD. It's not that we have a lack of
         | attention ("defecit" of attention, as the name suggests), it's
         | an impaired ability to direct it.
         | 
         | To abuse a metaphor, the sleep-deprivation-induced spontaneous
         | CSF flush is slamming on the brakes of a car, and ADHD related
         | attention shifts would be more like a drunk toddler is turning
         | the steering wheel wherever they please, but the gas/brakes
         | still work fine.
        
         | luciferin wrote:
         | I suppose it's possible, but it seems less likely to me because
         | ADHD is a life long neurodevelopmental disorder that shows
         | [visible physical changes in the brain on
         | scans](https://pmc.ncbi.nlm.nih.gov/articles/PMC7879851/). That
         | said, there are statistically more people with narcolepsy who
         | have ADHD, and the same goes for sleep apnea. There's a number
         | of hypotheses I've read as to why, to name a couple: related
         | epigenetic causes, or [possible misdiagnosis](https://pmc.ncbi.
         | nlm.nih.gov/articles/PMC7336577/) (narcolepsy is much harder to
         | diagnose than ADHD if you don't have textbook symptoms). So
         | there is definitely something there.
        
         | Citizen8396 wrote:
         | Disordered sleep can cause executive dysfunction similar to
         | ADHD, but it does not cause ADHD. It certainly can exacerbate
         | it or be diagnosed incorrectly.
        
         | Geee wrote:
         | Not sure if it's related, but I have way more ADHD-like
         | symptoms if I'm on late sleep schedule, but sleeping the same
         | amount of hours.
        
       | HEmanZ wrote:
       | I hope that the actual medical field starts taking note of this.
       | 
       | My wife still has to work 24 hour shifts with no sleep,
       | performing emergency surgeries no matter how long it has been
       | since she slept. During residency only a few years ago she and
       | her co-residents were almost weekly required to do 36 hour shifts
       | (on top of their regular 16 hours per day, 5 day per week
       | schedule) and once even a 48 hour shift when the hospital was
       | short staffed.
       | 
       | Of course I'm sure they won't. No one cares if doctors are over
       | worked.
        
         | lordnacho wrote:
         | I've never understood those long shifts. Unless a shift just
         | means you are there but sleeping, what is the reason for
         | allowing it? We don't let truck drivers do 24h shifts, why do
         | doctors the world over seem to do this?
        
           | munificent wrote:
           | My understanding is that the research shows that the harm to
           | patient care from information loss during doctor shift
           | turnover is worse than the harm from fatigued doctors.
           | 
           | Yes, a tired doctor sucks. But a tired doctor _who already
           | has the patient 's state loaded into their head_ may still be
           | better than doctor who is completely fresh in both senses.
           | 
           | It's a hard problem.
        
             | harperlee wrote:
             | That only works if the mean stay in the hospital (or at
             | least the critical care period) is several hours but also
             | way below 24h...
        
               | Timon3 wrote:
               | Longer shifts mean fewer shift turnovers for any patients
               | that stay a sufficient amount of time, especially if
               | longer than 24h.
               | 
               | The world doesn't run on boolean logic. A solution can
               | _improve_ an issue without solving it completely.
        
             | Fire-Dragon-DoL wrote:
             | What about the harm to the doctor themselves+the harm to
             | the patient? Would the sum of both be worse?
        
               | arjvik wrote:
               | One signed up knowing the risk
               | 
               | (not defending, I also think its insane, just devils
               | advocate)
        
             | thaumasiotes wrote:
             | > My understanding is that the research shows that the harm
             | to patient care from information loss during doctor shift
             | turnover is worse than the harm from fatigued doctors.
             | 
             | This would not appear to apply to emergency surgeries. They
             | aren't done by doctors who are familiar with the patient
             | anyway. (Neither are non-emergency surgeries. Surgeries are
             | done by doctors who do that kind of surgery. Familiarity
             | with the patient is useful in deciding what surgery should
             | be done, but not in doing the surgery.)
        
             | renewiltord wrote:
             | The European Working Time Directive has requirements for
             | rest, etc. Either Europeans have much better hand-off
             | procedures, they don't know how to comply with the rules
             | they make, or they're fucking idiots who are going to kill
             | people due to information loss during shift turnover. It
             | was proposed decades ago. I wonder what compliance is like
             | in Germany, etc.
        
             | K0HAX wrote:
             | Instead of 1 doctor covering a 24 hour shift, why not pair
             | them and overlap?
             | 
             | 12:00am - 6:00am: Doctor 1 and Doctor 4 are doing
             | everything together.
             | 
             | 6:00am - 12:00pm: Doctor 1 and Doctor 2 are doing
             | everything together.
             | 
             | 12:00pm - 6:00pm: Doctor 2 and Doctor 3 are doing
             | everything together.
             | 
             | 6:00pm - 12:00am: Doctor 3 and Doctor 4 are doing
             | everything together.
             | 
             | This way, all 4 doctors only do 12 hour shifts, and the
             | patient's state is maintained continuously through all 24
             | hours.
        
               | ineedaj0b wrote:
               | Doctors do not get along and that's too many Drs. Each
               | patient often has multiple speciality Drs visiting them
               | and reviewing their case up to 3 or 4 sometimes already.
               | Imagine being on consult and trying to figure out which
               | guy on a team of 4 you should talk to about such and
               | such.
        
               | someguyiguess wrote:
               | If engineers ran the world
        
               | lostlogin wrote:
               | That's a lot of handovers.
        
               | munificent wrote:
               | Here's an anecdote that might help answer. When my wife
               | was pregnant with our first doctor, she started
               | hemorrhaging spontaneously ten weeks before her due date.
               | We rushed to the ER.
               | 
               | 1. Shortly after, a doctor A came in, asked some
               | questions, looked at the chart, and told us she was
               | having the baby _tonight._ Holy shit our life is about to
               | get crazy and we 're going to be parents 2+ months early!
               | He leaves.
               | 
               | 2. Several hours later doctor B comes in. We ask about
               | delivery. "Oh, no. You're not going to have the baby now.
               | But you will have to be on bed rest until the due date."
               | Jesus, my wife is going to have to quit her job.
               | 
               | 4. Even more hours later, now the next morning, doctor C
               | arrives. "OK, you're free to go home. No bed rest needed.
               | Just let us know if anything else happens."
               | 
               | My general experience with doctors is that you get as
               | many unique opinions as there are doctors in the room.
               | This is not an indictment of the profession. Human bodies
               | are insanely complex, there is _way_ more variation
               | between them than most people realize, and doctors are
               | operating under very very limited time and information.
               | 
               | Having overlapping doctors would likely cause even more
               | patient confusion and increase the risk conflicting
               | treatments. Also, it would obviously double the cost of
               | care.
               | 
               | (My wife and baby were fine. Partial abruption. Very
               | scary and my daughter was born five weeks early, but no
               | other significant problems.)
        
             | arcticfox wrote:
             | > Yes, a tired doctor sucks. But a tired doctor who already
             | has the patient's state loaded into their head may still be
             | better than doctor who is completely fresh in both senses.
             | 
             | AI fixes this. Imagine the boot time of loading a patient's
             | state from dozens of labs and files vs. a summary that gets
             | you to exactly what they're going to end up remembering
             | anyways. And if a doctor finds something interesting that
             | the AI doesn't flag, they should be flagging it in the
             | chart for the next doctor anyways.
        
               | solsane wrote:
               | In my experience, AI summarization is a pretty lame
               | application. I don't really need a block of potentially
               | wrong, rephrased text. I've got a feeling that the same
               | applies to healthcare.
        
               | munificent wrote:
               | Jesus Christ you have to be fucking kidding me.
               | 
               | Your solution to information loss during doctor handover
               | is to insert a brainless hallucinating program with zero
               | responsibility into the middle?
        
           | cma wrote:
           | The AMA works to prevent importing doctors from other
           | countries, largely to maintain wages, but we don't have
           | enough doctors.
           | 
           | Doctors boards and AGME (partly governed by AMA, but there is
           | some amount of public representation) control residency
           | admissions and board certification. We don't necessarily want
           | low admissions standards, but there is a lot potential
           | conflict of interest in constraining supply.
           | 
           | Some states, I think I read Florida recently, have started
           | pushing back to allow in foreign doctors.
        
           | magicalhippo wrote:
           | Here in Norway the doctor's association have worked hard
           | against it, and talking to a relative which became a doctor
           | some years ago, it's primarly because they want to keep the
           | extra premium pay they get from the "uncomfortable hours" as
           | it's called here.
        
         | random3 wrote:
         | I think both doctors and patients would want a different system
         | for both doctors and patients. Having seen a poor performing
         | medical system, and comparing it with the US medical system,
         | all I can say it's that the US one doesn't seem designed to
         | optimize health and well being of patients and, based on
         | reading several articles representing doctors opinions, neither
         | doctors'.
         | 
         | I do think it's maximially optimized to extract revenue. That
         | can sometimes be good (e.g. good access to healthcare) but
         | often times it's not great.
         | 
         | Given healthcare, along with education should be a national
         | priority, both should be heavily "configured" to serve peoples'
         | goals first and any financial goal should be secondary
         | (although arguably useful).
         | 
         | I suspect the current shareholder structures from hedge funds
         | are (intentionally or not) driving things in the wrong
         | direction wrt to public health goals. This is article from a
         | few days ago is also interesting
         | https://news.ycombinator.com/item?id=45680695
        
         | jdthedisciple wrote:
         | Allow me to be a bit blunt here:
         | 
         | Don't you, as presumably a SWE in the US, make a sh!tton of
         | money?
         | 
         | Howcome your wife still is forced into such detrimental working
         | conditions?
        
           | cestith wrote:
           | Who said she was forced, and why the personal attack?
        
             | jdthedisciple wrote:
             | > still has to work 24 hour shifts with no sleep
             | 
             | Reads like being more or less forced to me, it doesn't to
             | you?
             | 
             | > and why the personal attack?
             | 
             | Not at all my intention! It's a genuine question, which I
             | would ask myself too were I in OP's shoes
        
               | cestith wrote:
               | I doubt her spouse makes her be a doctor. Most people who
               | go through premed and medical school are pretty dedicated
               | and driven on their own. This is a corporate vs labor
               | issue, and likely not a domestic issue. I'm sure he
               | dislikes it greatly, too.
        
               | HPsquared wrote:
               | It's not so much "forced", as "given an offer they can't
               | refuse".
        
           | switchbak wrote:
           | This is the nature of the medical system in North America,
           | and some other advanced nations. Also, you're not just being
           | blunt, you're being both ignorant and arrogant.
        
             | jdthedisciple wrote:
             | If OP feels the same way, I offer my heartfelt apologies.
             | 
             | I don't think what I said would come across this negatively
             | in person though, but okay..
        
             | cactusplant7374 wrote:
             | GP's wife isn't being forced into this profession and they
             | are making a lot of money from it. Do we need to offer
             | sympathy for all people with difficult working conditions
             | regardless of the remuneration?
        
           | astrange wrote:
           | A surgeon is going to make more than an SWE. Also, surgeons
           | are famously unhappy with anyone questioning any of their
           | decisions.
        
             | lostlogin wrote:
             | It's an interesting paradox.
             | 
             | Imagine doing your best to help someone and they die as a
             | direct result.
             | 
             | Then you get to go to work and deal with the next case.
             | 
             | Or the patient has life changing, negative outcomes. Damn,
             | that bad. Next case.
             | 
             | Living in that mental state takes a pretty unusual
             | character type. We can expect some extreme behaviour.
             | 
             | It's also interesting watching the change over time. The
             | trainee versus consultant, or the surgeon as they near
             | retirement.
             | 
             | I'm not a surgeon or a doctor and so I see a small part of
             | their world but see some of the perks (they get everything)
             | and some of the downsides, and there are a lot.
        
         | ineedaj0b wrote:
         | her at her worst is better than 90% of people at their best.
         | 
         | if you get through and into a good med school -match into
         | surgery- you are Peak in a way very few are.
         | 
         | I don't see this changing unless they reduce the requirements
         | for med school; if they let anyone in who wants in and force
         | that group to work 30hr shifts - you'll get enough bad outcomes
         | the system will change.
         | 
         | There was a study, I believe on nurses and shift durations. The
         | study found the nurses were happier with shorter shifts - but
         | the patients did worse. Patients come first.
         | 
         | I could see a group of Doctors loudly proclaiming love for
         | Donald Trump (and mentioning very much how great he is) and
         | pleading the case for a change and something happening. He is
         | an interesting president.
         | 
         | I would be interested in hearing a european drs perspective, I
         | heard they work shorter shifts (but no EU dr I met has
         | confirmed, it's like meeting a unicorn)
        
           | lostlogin wrote:
           | > her at her worst is better than 90% of people at their
           | best.
           | 
           | A fraction of a fraction of a percentage of people are good
           | at surgery.
           | 
           | If I need someone cutting me, I'd prefer someone good, and
           | that they were rested.
        
         | whamlastxmas wrote:
         | This stupid hazing ritual is only happening because of the AMA,
         | which is doing it for really stupid "because we had to" logic.
        
         | bmitc wrote:
         | Were these continual shifts? I thought that doctor's on shift
         | like this were given sleep rooms to sleep when they aren't
         | needed.
        
       | kurtis_reed wrote:
       | Title sucks
        
       | Olshansky wrote:
       | Need a cron job to flush that cache
        
       | shomp wrote:
       | In high school a friend of mine told me about "microsleep" and
       | how your brain will oscillate into it if you're under-rested.
       | This would align with that theory.
        
       | SilentM68 wrote:
       | That is very interesting. I have a somewhat related issue with
       | sleep cycles. This issue, waking around 3:00am every morning then
       | not going back to sleep until 6 or 7am, is not really a
       | productive sleep cycle. I read somewhere that taking a spoon of
       | sugary substance, like Raw Honey, MCT or Collagen, before going
       | to bed can replenish the brain of this energy, so it becomes
       | easier to fall asleep. I've been trying it with two to three
       | spoons of honey, right before hitting the sack to see if it can
       | help me fall asleep again. It seems to be having a somewhat
       | positive effect as it does not take me too long to go back to
       | sleep.
        
         | rsync wrote:
         | Extremely fine optimizations - like you are describing - only
         | make sense after the major, gross actions have already been
         | exhausted.
         | 
         | Do you have a regular, intensive, exercise routine with a good
         | mix of aerobic and resistance training?
         | 
         | Don't buy the fancy high flow air filter if you're not even
         | doing oil changes...
        
       | binary132 wrote:
       | What I'm picking up here is that if I can just get an automated
       | CSF circulator installed I won't need to sleep or get distracted
       | when I'm tired. That was the point of this article, right?
        
       | boogieknite wrote:
       | should have given them a cup of joe while in the fmri to see what
       | difference that made
        
       | gcanyon wrote:
       | What I want to know is: can we _trigger_ these flushes? My
       | grandfather died of /with Alzheimer's, and I'd prefer not to
       | follow in his footsteps. If we determine that these flushes are
       | key to good brain health, and there were a way either through a
       | pill or even a treatment to up the frequency of these flushes,
       | that would be awesome.
        
         | HPsquared wrote:
         | Choosing to sleep more, I guess.
        
         | pedalpete wrote:
         | We can't "trigger" the flushes, however, it looks like we can
         | increase the power of the pump.
         | 
         | This is specifically the area we work in traditionally called
         | slow-wave enhancement which is stimulating the restorative
         | function of sleep.
         | 
         | This paper [1] specifically looks at amyloid response as a
         | result of stimulation and shows a corresponding relationship
         | between stimulation response, amyloid response, and memory. I
         | wouldn't say it's putting a bow on the results, but it is a
         | very promising result.
         | 
         | If you're curious about what we're building, I'll be posting a
         | ShowHN next week which dives into some of the data in a way
         | regulatory requirements don't permit us to do on our website,
         | but until then, check out https://affectablesleep.com
         | 
         | [1] https://doi.org/10.1093/ageing/afad228
        
           | hammock wrote:
           | > We can't "trigger" the flushes
           | 
           | How do you know that?
        
             | pedalpete wrote:
             | I work in neurotech/sleeptech and this is the primary
             | function our work focuses on.
             | 
             | However, I also mis-stated that. It is possible to create a
             | slow-wave, however only through magnetic stimulation
             | (rTMS), but that is not realistic outside of a hospital
             | environment.
        
               | hammock wrote:
               | Ok awesome. Are you saying that because it is an
               | autonomic process or some other reason?
               | 
               | You will probably say no but I wonder if those yogis who
               | can exert some control over heart rate, blood pressure,
               | and breathing pattern might try to target this process as
               | well.
        
               | pedalpete wrote:
               | I'm just saying that based on known science. I don't know
               | if anyone has looked at if yogis, etc can control the
               | glymphatic system.
               | 
               | What blew my mind when I got into neuro just over 5 years
               | ago, is that the glymphatic system was only discovered in
               | 2012!!!! We have SO much to learn about the brain.
        
         | Muromec wrote:
         | I know a reliable way to trigger this. 400 gram of lamb, one
         | bell pepper, one or two leek, one zucchini, some random spices
         | (red chili pasta from the shop works a-okay), put in at slow
         | heat for an hour and a half, so by 4 in the evening it's ready
         | and you can close your laptop. Serve with rice or mercimek
         | chorbasi.
         | 
         | The fluids have no chance to not be flushed once you are done
         | with it.
        
       | assimpleaspossi wrote:
       | Maybe unrelated but, years ago, I had a job that had me criss-
       | crossing the country by plane Monday through Friday and sometimes
       | Saturday. So my sleep and the time zones and hotels could
       | sometimes mess with me.
       | 
       | One day, I went to a grocery store and mid-turn onto another
       | street, I forgot what city I was in. Worse, I was half a mile
       | from my apartment in my home town.
        
         | hollerith wrote:
         | How long did it take you to orient or to get home (whichever
         | one happened first)?
        
           | assimpleaspossi wrote:
           | It was very brief. Only a few seconds
        
       | handfuloflight wrote:
       | I can feel when this fluid hasn't properly flushed.
        
       | heywoods wrote:
       | This reminds me of delirium tremens a bit. Same compensatory
       | mechanism, different sleep process - or at least that's the
       | pattern I'm seeing.
       | 
       | The MIT study shows CSF waves--normally a sleep-only process that
       | flushes metabolic waste--intruding into wakefulness when you're
       | sleep-deprived. Your brain is apparently so desperate for the
       | cleanup that it forces the process to happen anyway. Cost:
       | attention lapses.
       | 
       | From what I've read, delirium tremens during alcohol withdrawal
       | seems to follow a similar pattern, except it's REM sleep
       | intruding into waking consciousness instead of CSF flushing.
       | 
       | [Polysomnographic studies from the
       | 1960s-80s](https://pubmed.ncbi.nlm.nih.gov/7318677/) documented
       | this. Patients in alcohol withdrawal exhibit what researchers
       | call ["Stage 1-REM"](https://www.sciencedirect.com/topics/neurosc
       | ience/delirium-t...)--a hybrid state where wakefulness and REM
       | sleep characteristics get mixed together. Right before full-blown
       | DTs, [some patients hit 100% Stage 1-REM](https://link.springer.c
       | om/chapter/10.1007/978-1-4757-0632-1_...). The hallucinations
       | appear to be [literally enacted dreams](https://www.sciencedirect
       | .com/science/article/abs/pii/S01651...) occurring while
       | technically awake. The sleep-wake boundary just completely breaks
       | down.
       | 
       | What strikes me is the system-level similarity here. Sleep
       | normally maintains clean states: you're either awake (alert,
       | reality-testing intact, no CSF flushing) or asleep (offline,
       | dreams permitted, maintenance running). But when the system gets
       | stressed enough--whether through sleep deprivation or the
       | neurochemical chaos of alcohol withdrawal--it seems to start
       | making desperate tradeoffs.
       | 
       | The brain apparently needs certain processes to run. Period.
       | Total no-brainer! CSF flushing can't wait indefinitely. Neither
       | can REM sleep, which serves its own critical functions. So when
       | normal sleep architecture fails, the system appears to force
       | these processes anyway, even though the conditions are completely
       | wrong for them.
       | 
       | Maybe that's why the costs are so specific. CSF intrusion during
       | wakefulness costs you attention. REM intrusion costs you reality
       | testing, because REM is the state where your brain accepts
       | impossible narratives without question. Same compensatory
       | mechanism, different critical process forced into the wrong
       | state.
       | 
       | What I find interesting is how the brain knows what lever it
       | needs to pull and how it pulls it. Sleep deprivation forces waste
       | removal. REM deprivation forces wakeful dream states; which might
       | be a side effect not the actual goal. The brain seems to know
       | what maintenance is overdue and attempts the repair, consequences
       | be damned.
        
       | hyperjeff wrote:
       | Back when I used to meditate regularly, I would find that an
       | extra meditation in the middle of a sleepless night would go a
       | long way toward pushing off the need for sleep. Generally,
       | meditating always left me in a slightly heightened awake state.
       | Perhaps the help with brain fluid regulation is a core reason for
       | both effects. (I should go back to meditating again.)
        
       | pedalpete wrote:
       | This is fascinating, and somewhat directly related to the work we
       | do increasing slow-wave response during sleep.
       | 
       | For those who are not aware, slow-wave are the hallmark of deep
       | sleep and closely linked to the flushing the glymphatic system,
       | which is what they are referring to in this article.
       | 
       | We can't create slow-waves, but we can increase their
       | effectiveness through precisely timed auditory stimulation. I'll
       | be posting a Show HN next week which dives into the data of how
       | this works, but if you want to know more, there is info on our
       | website and links to over 50 published peer-reviewed papers.
       | https://affectablesleep.com
       | 
       | This paper specifically looks at amyloid clearance as a result of
       | this glymphatic flush https://doi.org/10.1093/ageing/afad228
       | 
       | While many people will point to "getting more sleep" that isn't
       | really the answer. More time asleep does not automatically mean
       | increased glymphatic flush. Additionally, as we age, the power of
       | the pump gets weaker, and more sleep does not help with that.
       | 
       | We believe the focus on counting minutes of sleep misses the
       | point of what makes sleep truly restorative and beneficial, which
       | are the neurological processes, and downstream physiological
       | changes as a result. This is why we talk about restorative
       | function, and that should be the focus of sleep health, not time.
       | 
       | After all, you wouldn't measure your diet based on how much time
       | you spend chewing, would you?
        
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