[HN Gopher] Nobel Prize in Physiology or Medicine 2025
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Nobel Prize in Physiology or Medicine 2025
Author : lode
Score : 318 points
Date : 2025-10-06 09:41 UTC (13 hours ago)
(HTM) web link (www.nobelprize.org)
(TXT) w3m dump (www.nobelprize.org)
| A_D_E_P_T wrote:
| It's a win for nominative determinism. The name Shimon, in
| Japanese, directly translates to something like "Determined
| Scholar."
|
| It's also a fairly weird and old fashioned name. The sort of
| thing that would have been in style 120 years ago. (Meiji and
| early Taisho era.) Japanese names today are usually less literal.
| coef2 wrote:
| His name could be interpreted as "aspiring to be a scholar". I
| guess he's done an exceptional job living up to it.
| matsemann wrote:
| I love how Nobel Prize always have a "popular information" with
| nice layman description of what was discovered and why it was
| important. From the sidebar:
| https://www.nobelprize.org/prizes/medicine/2025/popular-info...
| NeutralForest wrote:
| There's usually two pieces, a short one that can be taken as is
| for the general press and another which goes more in depth at a
| university level I would say.
| haunter wrote:
| There are actually three
|
| The press release
| https://www.nobelprize.org/prizes/medicine/2025/press-
| releas...
|
| The popular science article
| https://www.nobelprize.org/prizes/medicine/2025/popular-
| info...
|
| And an advanced scientific paper usually written by the
| members of the commitee
| https://www.nobelprize.org/uploads/2025/10/advanced-
| medicine...
| NeutralForest wrote:
| Indeed!
| falcor84 wrote:
| And then later on there's of course the recipient's Nobel
| lecture, most of which are fantastic.
| haunter wrote:
| Ah it's the Nobel Prize week! If anyone curious about this week's
| schedule:
|
| Tuesday: physics. Wednesday: chemistry. Thursday: literature.
| Friday: peace. Monday: economics.
| Keyframe wrote:
| obligatory comment about how economics one isn't a Nobel prize.
| alkonaut wrote:
| Next Monday also isn't in this week so it all works out.
| echelon wrote:
| https://en.wikipedia.org/wiki/Nobel_Memorial_Prize_in_Econom.
| ..
|
| > Although the Prize in Economic Sciences was not one of the
| original five Nobel Prizes established by Alfred Nobel's
| will, it is considered a member of the Nobel Prize system,
| and is administered and referred to along with the Nobel
| Prizes by the Nobel Foundation. Winners of the Prize in
| Economic Sciences are chosen in a similar manner to and
| announced alongside the Nobel Prize recipients, and receive
| the Prize in Economic Sciences at the Nobel Prize Award
| Ceremony.
| l5870uoo9y wrote:
| I think it's more the Nobel Peace Prize that stands out.
| mlyle wrote:
| The peace prize stands out for being different.
|
| The economics one stands out for not being endowed by Nobel
| but instead Sveriges Riksbank well after his death (thus
| it's the Nobel _Memorial_ Prize in Economic Sciences).
|
| But it's administered by the Nobel Foundation, etc.
| marbro wrote:
| The Peace Prize stands out because sometimes it is given
| to someone who wages war such as Henry Kissinger or
| Barack Obama.
| vjvjvjvjghv wrote:
| Giving the prize to Obama, whose main achievement at the
| time was not to be Bush, was a disgrace and did huge
| damage to the image of the committee. And he did nothing
| after that that would have deserved a prize.
| astrange wrote:
| Bush's PEPFAR was so good that if they gave him the prize
| it'd be more deserved than many other people who have it.
| tombert wrote:
| It still kind of baffles me that there's no Nobel prize for
| mathematics.
|
| I know there are plenty of other math awards out there, so it's
| not really "worse" or anything, I have always just thought it
| was a weird omission.
| slider22 wrote:
| In the past here on HN, someone spoke of a set of books that were
| an incredible resource on the body's immune response. Does anyone
| know which books those were? I'm assuming they will get an update
| to include info on T-reg.
| fabian2k wrote:
| These discoveries are old enough to be in the textbooks
| already.
|
| Not sure what would be good popular science books. There is
| quite a lot on the immune system in the Alberts (Molecular
| Biology of the Cell), but that is maybe too much without solid
| biology background knowledge. The typical textbook is the
| Janeway (Immunology), but that's certainly too much.
|
| What I liked as an introductory textbook in general was
| Campbell Biology, but that covers essentially all of Biology.
| There is a chapter on the immune system as well.
|
| All those books are horribly expensive in the US, and still
| quite expensive in other countries, though.
| jsenn wrote:
| I don't know the post you're referring to but I highly
| recommend How the Immune System Works by Lauren Sompayrac. It
| explains the interesting parts without getting bogged down in
| the details of every signalling pathway, but without dumbing
| things down too much.
| blackbear_ wrote:
| As a general introduction I quite like this one: https://shop-
| us.kurzgesagt.org/products/immune-a-journey-int...
| smath wrote:
| "How the immune system works", Lauren Sompayrac
| davikr wrote:
| I'd use Abbas' Immunology as a standard textbook and
| Sompayrac's How The Immune System Works as a more
| straightforward, lean book on the immune system.
| marcelotournier wrote:
| First pattern that comes into mind after reading about a gene
| called "Foxp3" and immune targets:
|
| Man frantically shakes whole body, then raises dramatically his
| fist and screams: - FOX...
| aspenmayer wrote:
| Metal Gear..?
|
| https://breezewiki.com/metalgear/wiki/FOXDIE
|
| > FOXDIE (originally rendered as FoxDie) was an engineered
| retrovirus developed by the DIA for the Pentagon. It was
| programmed to kill specific people by recognizing a person's
| DNA, causing cardiac arrest.
| astrange wrote:
| https://en.wikipedia.org/wiki/Sonic_hedgehog_protein
|
| But:
|
| https://en.wikipedia.org/wiki/Sonic_hedgehog_protein#Former_...
| jelsisi wrote:
| Very excited to live in a timeline where autoimmune diseases
| could be cured. 40 people are already in remission from Lupus in
| a trial conducted last year.
| osnium123 wrote:
| It's interesting that two of the two American recipients weren't
| recognized by other awards like membership in the National
| Academy of Sciences or the National Academy of Medicine. Truly
| black horse candidates which makes this fun.
| dangle1 wrote:
| Funny anecdote that Dr. Brunkow thought she was being spammed
| when the Nobel Committee tried to inform her:
|
| >Brunkow, meanwhile, got the news of her prize from an AP
| photographer who came to her Seattle home in the early hours of
| the morning. She said she had ignored the earlier call from the
| Nobel Committee. "My phone rang and I saw a number from Sweden
| and thought: 'That's just, that's spam of some sort.'"
|
| https://www.oregonlive.com/pacific-northwest-news/2025/10/sc...
| tombert wrote:
| I can't say I would react too differently. There are so many
| emails or phone calls claiming you've won a big award or sum of
| money that end up being scams.
| pdxandi wrote:
| Am I understanding correctly that this Nobel prize is for work
| that was completed over 20 years ago? I'm not a biologist but
| it sounds like they discovered regulatory T cells together,
| which sounds relatively major. Is it typical for a Nobel prize
| to lag that kind of discovery for decades? Or is it only now
| that we understand how major the discovery was? Or maybe I'm
| just misunderstanding the discovery and the timeline.
| osnium123 wrote:
| Yes, many Nobel prizes are awarded for work that was
| completed decades ago in part to ensure that the work passes
| the test of time.
| serioussecurity wrote:
| Highs had a delay of 49 years from paper to prize, though he
| got the prize the year after his theory was experimentally
| confirmed.
| tverbeure wrote:
| Meanwhile, Fred Ramsdell probably still doesn't know he's won
| it because he's backpacking in Idaho.
|
| He'll be in for a surprise when he switches his phone back on.
| SkinTaco wrote:
| That's Idaho, USA for anyone who lives in one of the 194
| other countries in the world (yes we do exist!)
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