[HN Gopher] Bill Atkinson's psychedelic user interface
       ___________________________________________________________________
        
       Bill Atkinson's psychedelic user interface
        
       Author : cainxinth
       Score  : 344 points
       Date   : 2025-07-11 11:03 UTC (11 hours ago)
        
 (HTM) web link (patternproject.substack.com)
 (TXT) w3m dump (patternproject.substack.com)
        
       | xeonmc wrote:
       | Ok, where is this psychedelic community found?
       | 
       | I must sample their handles for videogame character names.
        
         | diggan wrote:
         | > Ok, where is this psychedelic community found?
         | 
         | Bit like asking where all the beer drinkers are! People who are
         | into psychedelics come from all walks of life and we're
         | everywhere :) Start talking about fringe stuff with people and
         | eventually you'll stumble upon others.
        
         | firtoz wrote:
         | There are some decent communities in Discord, for both research
         | oriented but also hobby oriented communities of psychedelics.
        
         | trenbologna wrote:
         | Burning man and other festivals are a good resource
        
           | copperx wrote:
           | Bill disliked the expensive retreat hurdle.
        
         | dudeinjapan wrote:
         | Visit your local Hobby Lobby and ask around.
        
         | zeckalpha wrote:
         | The article mentions Erowid
        
       | demiters wrote:
       | Not a big fan of the ongoing productisation of transcendental,
       | possibly brain-scrambling experiences. Keeping them somewhat less
       | accessible tends to filter out people who don't do their homework
       | to understand the substance and who consider it just another
       | novel experience to try on a whim, which increases the risk of
       | negative outcomes.
        
         | hnlmorg wrote:
         | That has been various governments approach to drugs for
         | literally decades and it got us nowhere.
         | 
         | The problem isnt that this still is casually available. Drugs
         | have been casually available since forever.
         | 
         | The problem is that pushing drug usage to the fringes makes it
         | less safe for people who haven't done their homework.
         | Ironically the exact opposite of that you claimed.
        
           | demiters wrote:
           | You're right. I'm all for across-the-board decriminalisation
           | btw. But I don't really know where a responsible balance
           | would be for psychedelic availability, my intuition is we
           | shouldn't be aiming at OTC disposable DMT vapes etc.
        
             | JKCalhoun wrote:
             | Perhaps administration of the drug from a professional?
             | Make the treatment an affordable and legal option.
        
               | athenot wrote:
               | The difficulty here is professional skill entails money,
               | money entails risk management, risk management entails
               | legalities.
               | 
               | The only way in the US is to have a powerful lobby that
               | can fight to ensure broad waivers stand up in court, like
               | the NRA: you can buy a gun and literally shoot yourself
               | in the foot.
               | 
               | But if transaction, money, service, profession are all
               | removed, then under a co-op / non profit this might work.
               | Of course, those structures are also vulnerable to well-
               | funded legal opponents.
               | 
               | Some European countries do provide a framework for this
               | but it's more from a public health perspective and to
               | eliminate the raison-d'etre of criminal drug
               | organizations.
        
               | zoklet-enjoyer wrote:
               | That sounds awful. I'll stick to my home and nature
        
           | mathiaspoint wrote:
           | I think with psychedelics it's fine. The problems you're
           | talking about are with addictive stimulants.
        
             | asveikau wrote:
             | With psychedelics the risk profile is very different.
             | Firstly, people can do harmful things during the trip.
             | Second, a more vague, difficult to measure and predict
             | concern around long term psychological effects to some
             | people.
        
               | mathiaspoint wrote:
               | Right, my pronoun is dangling here. "It" was meant to
               | refer to the status quo of making them inaccessible
               | without a lot of difficulty and breaking the law.
        
         | perching_aix wrote:
         | > do their homework to understand the substance
         | 
         | Is that actually _the_ common thing to do amongst recreational
         | psychadelics users (i.e. is there research backing this up)?
         | 
         | And how do these folks "understand the substance(s)"? We
         | (humanity) know very little about how the brain works
         | comparatively as far as I'm aware, and psychadelics research is
         | further relatively lacking due to regulatory and funding
         | constraints. Most resources I hear of just seem to be
         | compilations of anecdata, frequently muddled with subjective
         | remarks.
        
           | demiters wrote:
           | I can only speak for my own circle that I know about where
           | test kits are the norm. Anecdata isn't ideal but it does seem
           | to be valuable as long as the reader considers both positive
           | and negative reports equally and understands the risks rather
           | than just yoloing. I still consider Erowid a great harm
           | reduction resource, TripSit wiki is also fantastic, and I
           | very much support the approach taken by the Subjective Effect
           | Index website.
        
             | perching_aix wrote:
             | I see, fair enough. I'd be just hesitant to say "xy keeps
             | yz from doing zx" without data, cause it sounds like a
             | claim (or even a fact) rather than an opinion/anecdote, and
             | it's pretty hard to pick up on this difference.
             | 
             | We were able to clarify it and we're both being decent
             | sports about the topic, but you can imagine how well this
             | might go over in less careful and open minded situations.
             | Or even desperate ones.
        
         | zeta0134 wrote:
         | I suppose this is a dangerous counterargument to make,
         | especially as I'm not a substance user at all myself, but...
         | what's wrong with wanting to seek out novel experiences? I'd
         | much rather folks who wish to do this be able to do so safely,
         | with good sources of information about those risks and with a
         | support network that is allowed to talk about it. I feel like
         | the taboo nature of substances in general causes folks with
         | this interest to hide it from their peers, exactly the people
         | who would otherwise be first in line to spot problems and offer
         | assistance. Shouldn't it be okay to talk about it?
        
           | lostmsu wrote:
           | They are totally OK as long as healthcare is not socialized.
        
             | Gravityloss wrote:
             | There's angles to socialization. If a person with brain
             | issues gets free doctor visits and a medicine, that is at
             | cost to society.
             | 
             | If they are safe to be around and are able to hold a job or
             | have children, then there's societal benefits gained. One
             | could consider the treatment costs as investments.
             | 
             | If that person was untreated and they did something
             | unpleasant or bad in public, or ended up in prison, that
             | also has a cost to society though it might be more complex
             | to quantify.
        
               | lostmsu wrote:
               | You are assuming treatment benefits, but the comment was
               | about "recreational" use and its consequences.
        
             | dtj1123 wrote:
             | Does that line of reasoning extend to things like fast food
             | and motorcycles in your eyes? Not trying to undermine your
             | point, just genuinely curious.
        
               | patcon wrote:
               | > things like fast food and motorcycles in your eyes?
               | 
               | motorcycles...? in... my eyes?
               | 
               | What wizardry is this? First "computers in my brain", now
               | this. I'll have the singularity that you're smoking pls
               | :)
               | 
               | EDIT: was at first genuinely confused, and then tickled
               | by my own misunderstanding
        
               | lostmsu wrote:
               | I don't see why not. Maybe no need to ban altogether, but
               | a heavy tax on both might be useful. For motorbikes maybe
               | just exclude accidents from coverage.
        
               | bee_rider wrote:
               | I guess they aren't very widespread anymore, but should
               | this cover police who ride motorbikes? Or farm/ranch
               | workers (they might ride ATVs)?
               | 
               | I guess we could do something like:
               | <normal coverage> - <adjustment for risky behavior> +
               | <adjustment for pro-social outcomes>
               | 
               | But I think we will have trouble puzzling out the last
               | term!
        
               | lostmsu wrote:
               | One has to draw the line somewhere. What you are doing is
               | called a slippery slope fallacy.
        
               | bee_rider wrote:
               | I'm not sure it is a slippery slope. With a slippery
               | slope we expand the scenario through a sequence of "if X,
               | when what's to stop Y," right?
               | 
               | Motorcycle cops are an obvious subset of people who ride
               | motorcycles. It isn't an extension at all to include them
               | in your logic.
               | 
               | ATVs might be more of an extension. But, I bet if we
               | wanted to we could find all sorts of jobs that are more
               | dangerous than motorcycle riding.
               | 
               | (Edit: just to be specific, you say we have to draw the
               | line somewhere. Well, then where?)
        
               | lostmsu wrote:
               | There's a long list of topics where this particular
               | reasoning could draw a line somewhere. It is unfeasible
               | and pointless to cover them all unless they are all
               | banned or all allowed (this essentially is the current
               | state +- AFAIK).
               | 
               | I'd say it is worth looking at redrawing that based on
               | the maximum effect achieved. Drugs would be at the top of
               | this list, followed by motor vehicle use and unhealthy
               | foods. There is probably not enough justification to go
               | beyond the 3.
        
               | bee_rider wrote:
               | I'm not clear on what the effect actually is. If it is
               | cost reduction, not sure where motorcycles should be on
               | the list (they are probably more costly for life
               | insurance agencies than for health insurance ones...).
               | 
               | I guess I've been beating around the bush, but my point
               | is that targeting drugs specifically for this sort of
               | thing would seem kind of, I dunno, puritanical to me (as
               | someone who doesn't partake). I'd rather just insure
               | everybody and hope they don't hurt themselves, just out
               | of their own self interest.
        
               | daedrdev wrote:
               | I think motorcyclists should pay more for health
               | insurance insurance considering they will use it way more
               | often no matter how well a driver they are, the risks are
               | simply always present.
        
               | aeonik wrote:
               | If they die more often in accidents, and their organs are
               | harvested from that, they should pay less though, right?
        
           | wbl wrote:
           | Four entered the garden: Ben Azzi, Ben Zoma, Acher and Akiva.
           | One looked and died. One looked and was harmed. One cut down
           | all the trees. And one entered in peace and departed in
           | peace.
        
             | mock-possum wrote:
             | Lemme guess, Ben Zoma was the peaceful one?
        
               | aradox66 wrote:
               | Nope! Rabbi Akiva, who, as the story goes, was an
               | illiterate shepherd until he started studying in his 40s,
               | and went on to become one of the most renowned scholars
               | of his era. This is why some Jewish tradition teaches
               | that for mystical study, one should wait until the age of
               | 40
        
             | aswegs8 wrote:
             | I didn't know this story, but thanks for pointing this out.
             | It's scary how people in this thread talk about
             | hallucinogens like they could not ruin your life.
             | 
             | Citing Sam Harris:
             | 
             | "Ingesting a powerful dose of a psychedelic drug is like
             | strapping oneself to a rocket without a guidance system.
             | One might wind up somewhere worth going, and, depending on
             | the compound and one's "set and setting," certain
             | trajectories are more likely than others. But however
             | methodically one prepares for the voyage, one can still be
             | hurled into states of mind so painful and confusing as to
             | be indistinguishable from psychosis."
             | 
             | "This is not to say that everyone should take psychedelics.
             | As I will make clear below, these drugs pose certain
             | dangers. Undoubtedly, some people cannot afford to give the
             | anchor of sanity even the slightest tug."
        
         | diggan wrote:
         | > Keeping them somewhat less accessible
         | 
         | I agree this is important, which is why psychedelics should be
         | legalized so there is at least some sort of control instead of
         | the current approach where 14 year olds can easier get their
         | hands on it.
        
         | Etheryte wrote:
         | I'm of very two minds on this topic. On one hand, it's widely
         | accepted that most (not to say all) drugs leave a permanent
         | mark on brains that are not yet fully developed, so teenagers
         | who are often most curious about these things. Gated access is
         | highly desirable in this context, especially as you can't take
         | self regulation for granted. On the other hand, many of these
         | substances show great promise in many clinical trials for a
         | wide variety of issues, and decades of hostile legislation has
         | kept all of that on the back foot. Openly sharing information
         | about these topics can help people make more informed choices
         | whereas those who came before them often had to go it blind.
        
           | BolexNOLA wrote:
           | Yeah - I feel like we need a little bit more of a stripped
           | down approach to drugs in the US. If you're 18 or under,
           | there need to be a lot of restrictions because we know for a
           | fact that a lot of these things have a profound negative
           | impact on brain development, and we also know that we don't
           | even fully understand the extent to which various mind
           | altering substances can impact development. It's just safer
           | to say "no" until then as much as I am loath to endorse
           | anything remotely akin to prohibition culture.
           | 
           | Teens will always get their hands on things so it's up to
           | parents to teach kids how to be safe around drugs and
           | alcohol, but I know I personally will be really trying to
           | communicate to my kids that they need to wait until they're
           | 18 to really start exploring all this stuff. I know they will
           | before that, but as long as it's a little experimentation
           | here and there and not regular use I'll consider it a
           | success.
           | 
           | Once you're past 18 or so, it needs to be all about education
           | and general availability for most substances. Safe usage and
           | community protections (such as not driving while intoxicated)
           | should be the #1 goal.
        
             | 512 wrote:
             | > I know they will before that
             | 
             | I'm curious in what demographic/location context you're in
             | to say that. As a teen I wasn't aware of anyone in my
             | social circles experimenting with drugs and would estimate
             | usage to be <10% and from very particular kinds of people.
        
               | BolexNOLA wrote:
               | Teenagers (in the US) before they go to college pretty
               | typically at least try weed and alcohol at some point.
               | Whether or not they tell their parents is a different
               | story entirely
        
               | jjcob wrote:
               | I was on a student exchange in the US at age ~15 and was
               | offered both weed and alcohol. Funnily enough, weed
               | seemed to be easier to get since dealers don't care about
               | your age. For alcohol you needed to find someone older
               | than 21 who'd buy it for you.
        
           | justinrubek wrote:
           | I'd be interested in seeing specifics on brain development.
           | When are they "fully developed" or what is a sufficient point
           | that they could be considered to be. What other things do we
           | practice that should be gated around brain development?
        
         | t-3 wrote:
         | I disagree. Every time I've seen someone get a "bad trip",
         | they're people who read a lot and worked themselves into a
         | state of anxiety over the fact that something could go wrong.
         | If they had just approached it like "ooh lets get high and have
         | fun" rather than "I have to do X, Y, Z or else it's going to be
         | horrible!", they would have probably been OK. Hallucinogens
         | have _way_ too much gatekeeping and mysticalization around them
         | for what they are.
         | 
         | Understanding the risks of buying potentially adulterated or
         | counterfeit products is another thing entirely, which would be
         | helped greatly by increased commodification and legalization.
        
           | hampowder wrote:
           | Whilst that might true as per your observations, I've also
           | seen people do zero research, take a substance in the wrong
           | place/frame of mind, and subsequently had a more turbulent
           | experience than they were expecting
        
             | patcon wrote:
             | Yes to both.
             | 
             | We often attract certain types of people, and have a wealth
             | of experience with that type.
             | 
             | We probably all take this as obvious knowledge. But only
             | when I uncomfortably enter a group of people unlike me --
             | and feel totally alienated not just by their norms and
             | assumptions, but their misunderstandings of my own -- only
             | then do I truly confront the implications in a visceral,
             | non-academic sense :)
        
             | esseph wrote:
             | That's true with anything, though.
        
           | colecut wrote:
           | I know two people who had prolonged psychotic episodes, as
           | in, for weeks they were in their own world. These were both
           | people who had many fun/enjoyable experiences beforehand.
           | 
           | I myself have had bad / hell like experiences a small
           | percentage of the time, despite literal hundreds of good
           | experiences prior.
           | 
           | Becoming a father many years ago significantly altered my
           | trip experience.
           | 
           | Dosage also plays a strong role..
           | 
           | These things are generally less toxic than alcohol and it is
           | criminal to punish someone for having them or using them..
           | But they are also extremely powerful, and despite potential
           | amazing experiences, do carry risks.
           | 
           | And they are definitely not for everyone.
        
             | Bnichs wrote:
             | Can you explain how it changed after being a father?
        
               | colecut wrote:
               | I tripped a lot in my early 20s, a whole lot, and never
               | had a bad time. Well, I had some uncomfortable
               | experiences, but not what I can now call a bad trip.
               | 
               | One of my first times after, in my experience, I
               | literally went to hell. I was convinced I was on the
               | outskirts, all the people at the party around me were
               | demons, I was about to be tortured forever, and I was
               | never going to see my son again and he was going to grow
               | up without me..
               | 
               | I convinced myself I was in that position because I had
               | wrecked and killed someone, and my punishment was forever
               | replaying the experiencing of a life where I would grow
               | up to have a son, only to have him ripped away from me,
               | reminded of what I did, and then tortured for some nearly
               | eternal amount of time....
               | 
               | Any conversations people had with me at the time, I heard
               | the words they were saying but completely twisted the
               | meaning of the words to fit whatever crazy narrative was
               | going on in my head.
               | 
               | This has happened 4 or 5 times. Despite being familiar
               | with the experience, in my mind it just reinforces that I
               | am in a "loop" at the time, about to be tortured again..
               | 
               | It's happened with LSD, Mushrooms, and surprisingly even
               | ketamine. *edit it also happened during an intense changa
               | experience with a shaman in Tijuana, which was my most
               | intense experience with anything to date..
               | 
               | You'd think I would not take this stuff anymore =p I have
               | at least slowed down considerably...
        
               | copperx wrote:
               | Regarding your trip to hell, I'm interested to know if
               | you have a lifelong belief in heaven and hell, or if it
               | came by itself during the trip.
               | 
               | As an atheist with no supernatural beliefs (that I know
               | of), I wonder if a trip on LSD for me would just be
               | boring, or if these supernatural things become real
               | during a trip even if you don't truly believe in them.
        
               | colecut wrote:
               | I am definitely influenced by Christianity..
               | 
               | Regardless of your beliefs, whatever your experience, I
               | highly doubt you would find it "boring".
               | 
               | I can't even imagine that really, it would take a very
               | boring person.
               | 
               | I've heard a lot of acid stories, but never "I was just
               | kind of bored"
        
               | dekhn wrote:
               | It's unlikely you'd find it boring simply because you're
               | an atheist. The experience is typically quite intense,
               | although it's dose-dependent as well as setting-
               | dependent. I'm agnostic but my own experience was a
               | heightened sense of panpsychism which went away later,
               | because my rational, scientific mind didn't find the idea
               | highly plausible.
        
             | 01100011 wrote:
             | Also worth noting that persistent negative effects do not
             | require a bad trip. You can have a wonderful time and still
             | have long lasting issues.
        
           | turnsout wrote:
           | I have a family member who jumped off a balcony on LSD and
           | needed extensive reconstructive facial surgery. I'd call that
           | a pretty bad trip. It's kind of kept me away from anything
           | more than mushrooms.
        
         | Someone wrote:
         | It also makes doing your homework a lot harder. If I want to
         | buy alcohol, I can go to a shop and can get something that's
         | correctly labeled with an alcohol percentage and is highly
         | unlikely to contain methanol.
         | 
         | If I go buy some psychedelic, chances are it is diluted or
         | laced, so I would have to know how to test that what they sell
         | me is what I asked for.
        
           | allears wrote:
           | There are jurisdictions where it's legal, and shops that will
           | ship it virtually anywhere. The product is pure, tested, and
           | consistent.
           | 
           | Of course you have to find such a shop (hint: try Canada),
           | and it's still a lot of hassle for something that should be
           | perfectly legal, and is, in many places.
        
         | throwforfeds wrote:
         | The thing that bothers me the most are the companies out here
         | trying to get psychedelics to a state where they own the tech
         | and can try to make as much money as possible off of it. Not so
         | much the part where it becomes more available with consistent
         | quality for more users.
         | 
         | I was getting ads for MindMed's clinical trials of their LSD
         | analogue a few months back and was considering signing up for
         | it, as I'm totally down with more scientific research on these
         | compounds. However, the idea that a corporation with a patent
         | on an analogue that is lobbying to make it so their version is
         | the one that is approved is kinda the worst. We already have
         | LSD, it's cheap and it's amazing, yet here we are marching down
         | the road of some patented version being the one that's approved
         | for use. I get that these companies want to fund research, but
         | this isn't the way.
        
           | jamal-kumar wrote:
           | Welcome to the USA. Psychedelics are just the tip of an
           | iceberg here. There's shit like highly effective cough
           | medicines or antidepressants available in other countries
           | which show promise in saving lives but nope mired in patent
           | stuff and corrupt regulation...
           | 
           | https://lfpress.com/news/local-news/european-cough-
           | medicine-...
        
         | havefunbesafe wrote:
         | The high horse of HN generally suggests that every person on
         | the planet does empirical research on every step of their
         | journey through life. I've personally seen several, otherwise
         | normal people, one-shot their brain into purgatory with
         | hallucinogens.
        
         | jexe wrote:
         | Incidental gatekeeping by leaving it on the black market isn't
         | the way to keep it safe, quite the opposite - that poses a lot
         | of dangerous risks.
         | 
         | Bringing it into the light under thoughtful consideration and
         | openly discussing and encouraging harm prevention is the only
         | way to make this safe. Everyone should have the right to to
         | exploring this if they want to, and there should be plenty of
         | open discussion, research, and education. I really appreciate
         | the open-source approach here, the spirit of this movement
         | feels like the right thing for humanity.
        
         | flufluflufluffy wrote:
         | I feel similar about this productisation but for slightly
         | different reasons. Psychedelics can provide a sacred
         | experience, at least they have for me, and I treat each
         | psychedelic experience I have as a sacred ritual. It's a
         | sacrament. So forcing them into the materialist, capitalist
         | system we currently have just feels so wrong. It'd be like a
         | company coming out with pre-blessed Eucharist cookies. But
         | worse because what you are shown so often reveals how insidious
         | capitalism is, and how there is so much more than the material
         | realm. I know this is just my personal view and experience.
         | Anyway, I don't feel so bad about LightWand as the whole point
         | was the open source, sharing nature.
        
         | mock-possum wrote:
         | I'm fine with 'less accessible' - I am not fine with
         | 'criminal.'
        
         | dkarl wrote:
         | > Keeping them somewhat less accessible tends to filter out
         | people who don't do their homework
         | 
         | I strongly disagree. Your circles might be different, but in my
         | experience, wanting to do your homework makes it less
         | accessible, because it tends to put you at odds with the people
         | who are otherwise eager to grant you access. They want people
         | with a certain mindset and an up-front faith in the process.
         | They want people who aren't careful about ingesting
         | psychoactive substances, are eager to put their mental health
         | in the hands of some guy they barely know, and are going to
         | blame their own baggage or spiritual shortcomings if it doesn't
         | go well.
         | 
         | These drugs, and many others, are already pretty accessible if
         | you are willing to take that heedless approach.
         | 
         | In contrast, the approach described in the article is expressly
         | tailored for people who want to be careful and do their
         | homework. It's for people who have access to the drug and
         | implicitly already have access to cruder ways of using it, but
         | who want to put in extra effort for a more controlled
         | experience.
        
         | 01100011 wrote:
         | Basically this. Many times I've gotten too casual with them and
         | then been reminded that they are not a party drug. Persistent
         | HPPD(ok, redundant) and long lasting anxiety and/or motor
         | issues(tics).. inability to focus. It's great that there are
         | people who can gobble psychs like candy and not have
         | issues(that they're aware of anyway) but they need to chill on
         | trying to get everyone to trip out. I get it. I felt that
         | "everyone should try this" vibe. But seriously, no. Don't take
         | people's psychology lightly.
        
       | fedeb95 wrote:
       | thinking that our own judgement is better than a doctor
       | judgement, supported by a vast community and shared knowledge, is
       | epistemically interesting. Beware that I'm not saying that
       | doctors, or the scientific community, can't be wrong, everyone
       | can be wrong, even ourselves.
       | 
       | Personally, I'd rather have a proper doctor prescribe me said
       | medicine than take it myself.
        
         | RamblingCTO wrote:
         | I'd say it's irrelevant. Doctors typically have no exposure,
         | interest nor knowledge about these things. So they are not the
         | ones to have an opinion about it.
        
           | JKCalhoun wrote:
           | We should fix that then. (Timothy Leary was in fact a doctor.
           | Perhaps though his overly zealous enthusiasm for LSD makes
           | him not the ideal example in this case though.)
        
             | RamblingCTO wrote:
             | Not sure tbh. This is still in its infancy and not "stable"
             | enough for a bigger adoption rate. So while we're still
             | researching I feel like it's ok that we don't get it out to
             | the masses.
        
         | soulofmischief wrote:
         | In an ideal world maybe, but in the real world, most doctors
         | are conditioned by US propaganda and the War on Drugs. Their
         | views are compromised.
         | 
         | Furthermore, I've had mixed experiences with health
         | professionals. It took me 10 years across multiple clinics and
         | states to get diagnosed with gout that I've had since at least
         | my late teens. Laughed out of multiple doctor's offices because
         | I'm a "healthy young male" even though each day and night was
         | filled with excruciating pain and drastically reduced mobility.
         | "Full test panels" that _specifically_ did not test my uric
         | acid, because no healthy young male has gout.
         | 
         | No mention of gout ever to me, of course. I had to self
         | diagnose as the disease progressed due to lack of treatment.
         | Got my diagnosis confirmed by a physician's assistant, because
         | both doctors at that clinic were on vacation at the same time
         | for like the third time that quarter. He ordered a uric acid
         | test, and was surprised that I'd never been offered one.
         | 
         | Both doctors had _literally_ laughed me out of the office over
         | the previous months. But I was persistent and it turns out the
         | physician 's assistant there was both more thorough and more
         | knowledgeable than either doctor, helping me finally begin a
         | path to treatment. I was damn near about to kill myself from a
         | decade of extraordinary pain. From my discussions with older,
         | typical gout sufferers, my case is extraordinarily bad and most
         | of them only experience mild pain.
         | 
         | It's equally as silly to place 100% trust in doctors as it is
         | to place 0% trust in them.
        
           | z3c0 wrote:
           | When there's millions of doctors, not only are there going to
           | be more mediocre doctors than anything, but there has to be a
           | bottom of the barrel as well.
           | 
           | It took me years to be diagnosed with PTSD, a problem I knew
           | I had. Because I am not a vet, I had to go through every
           | other diagnosis first -- schizo, bipolar, borderline -- each
           | with a new set of pills to take. Some of the shrinks who
           | diagnosed me wouldn't do anything but open my file, make some
           | remarks, and fill out a prescription, with nary any eye
           | contact.
           | 
           | Finally got a very expensive doctor who wasn't under the
           | thumb of insurance companies. Her first question, upon
           | hearing my issues, was "how is your sleep?" "I don't, really"
           | was my reply. Screened me for PTSD and I clocked 76/80 pts.
           | She set me up with the proper therapy, and within a year, I
           | was screening at 30/80 pts. All it took was asking me one
           | question that wasn't loaded towards the doctors favorite
           | diagnosis & prescription.
        
           | 1718627440 wrote:
           | Isn't every medicine a drug, since a drug with medical
           | application in the right dose is just called medicine?
        
         | hiddencost wrote:
         | Given that the current regime is bringing back measles, appeals
         | to authority are becoming fraught.
        
         | AyyEye wrote:
         | After seeing someone I love tortured for weeks at a hospital
         | primarily because every one of the doctors was convinced they
         | knew better than her -- I'm very much on the 'we can do just
         | fine on our own' train. Do some research, use good sources, let
         | docs stop you from bleeding out if it comes to that.
        
         | gwbas1c wrote:
         | > thinking that our own judgement is better than a doctor
         | judgement, supported by a vast community and shared knowledge,
         | is epistemically interesting.
         | 
         | The medical community is concerned with physical health, mental
         | health, ect.
         | 
         | The Psychedelic community is more like a religion; it is "vast"
         | and there is a lot of "shared knowledge" if you go looking. The
         | thing is, western medicine's purpose really isn't to do the
         | kind of thing that psychedelics are for.
         | 
         | It's probably better not to conflate the two communities,
         | because they use drugs for very different purposes.
         | 
         | A different way to say it: Don't confuse the pharmacy and the
         | liquor store.
        
           | esseph wrote:
           | This is absolutely /bullshit/.
           | 
           | That medical doctor doesn't even know how most of the
           | medications work, or why!
           | 
           | If it was just about "health" a lot of things with our modern
           | medical care would be different.
        
             | 1718627440 wrote:
             | Isn't this what the years-long studies and rigorous state
             | examination is for? How would they selecting medication,
             | when they wouldn't know the mechanism of action?
        
         | corry wrote:
         | I agree with you for the most part. But the same medical
         | establishment that pumped opioids everywhere, demonized fat
         | instead of sugar, claimed tobacco was fine, overprescribed
         | mental health drugs, etc is perhaps not a slam-dunk example of
         | why we should trust the "expert consensus" on emerging
         | treatments and techniques.
         | 
         | Compounding the issue is the eye-rolling hypocrisy that in the
         | so-called "Land of the Free", a healthcare system controlled by
         | the gatekeepers of big pharma and for-profit companies gets a
         | blind pass... but putting certain plants (that you can grow
         | yourself) into your own body is considered a serious felony...?
         | 
         | There's at least a sliver of daylight here that mean YMMV
         | (which I'm sure you and I would agree on) - but if you lack the
         | freedom to choose anyways, then it doesn't matter. And the
         | people who decide for you are clearly part of a system that is
         | compromised by regulatory capture, political polarization, and
         | the insatiable greed of American healthcare.
        
         | spjt wrote:
         | With things the way they are, it's not hard to be more
         | knowledgeable about a condition than your doctor. Doctors have
         | to know about all the possible conditions people can have, I
         | only have to know about the one I have, so I've spent more time
         | researching it than the doctor.
         | 
         | If you don't know what's wrong with you, then a doctor is
         | absolutely the way to go. But if you already have a diagnosis,
         | you can go spend time researching it, the doctor isn't going to
         | do that.
        
       | croisillon wrote:
       | the first pic looks like Jobs and Bill Watterson
        
       | WillAdams wrote:
       | For the technological context and result:
       | 
       | https://www.folklore.org/Joining_Apple_Computer.html
       | 
       | Still very sad that HyperCard got sidelined and that even its
       | successor, Livecode abandoned the idea of being available to
       | everyone --- though it looks as if folks are still working that:
       | 
       | https://openxtalk.org/
        
         | wvlia5 wrote:
         | This is off-topic, we are discussing drugs here.
        
           | LocalH wrote:
           | It's not off-topic, it's the intersection of two things that
           | Bill Atkinson was extremely passionate about.
        
           | phaedryx wrote:
           | Hypercard was inspired by an LSD trip.
        
           | Ylpertnodi wrote:
           | Perhaps the gp's comment was written and posted whilst being
           | smashed, and that's just one of the effects.
        
           | WillAdams wrote:
           | which the link in question references:
           | 
           | >Inspired by a mind-expanding LSD journey in 1985, I designed
           | the HyperCard authoring system that enabled non-programmers
           | to make their own interactive media.
        
       | Euphorbium wrote:
       | I have not used 5-meo, but for n,n DMT the vape is without a
       | doubt the most convenient method.
        
         | gavinray wrote:
         | I've done it a few times. Unlike DMT, you don't have to
         | vaporize it.
         | 
         | It's active intranasally and well as buccally/sublingually.
         | 
         | Effects-wise, it feels roughly identical to DMT but with a
         | longer duration.
        
           | fer wrote:
           | I found it significantly less visual. As in, about as
           | immersive, but somewhat lacking visual depth/detail to
           | things. But everyone's different anyway.
        
           | gehwartzen wrote:
           | To me it feels like a completely different drug compared to
           | nnDMT. 5-meo-DMT also feels very different depending on the
           | roa from my experience (vaped vs IM)
        
             | wvlia5 wrote:
             | Expand on roa effect difference?
        
             | gavinray wrote:
             | Ah, a fellow "I've IM'ed tryptamines" person.
             | 
             | I made this mistake exactly once, with 4-AcO-DMT.
             | 
             | That was the last time I ever did such a thing.
        
               | Euphorbium wrote:
               | Can you expand on this? I just so happen to have
               | evrything to try this, but never even considered it.
        
               | gavinray wrote:
               | I dissolved 20mg of 4-AcO-DMT in 1mL of bacteriostatic
               | water in a sealed, sterile vial and then injected it
               | intramuscularly into my glute.
               | 
               | (If you do this, make sure you inject the upper-outer
               | quadrant. The closer to your midline you go, the further
               | the risk of you hitting a nerve.)
               | 
               | If you're very experienced and want to do it for
               | novelty's sake, go for it; I'd warn you, but anyone
               | considering this should know what they're likely in for.
               | 
               | Nearly immediately after injection, I became so filled
               | with vibrating, psychedelic energy I thought my soul was
               | going to be ripped from my body. I had to clutch the edge
               | of the sink, trying not to vomit while staring at the
               | exploding fractals swirling in the metallic reflection.
               | 
               | It only lasts about 2 hours. I'd not particularly rate
               | the experience as "good".
        
               | esseph wrote:
               | Thank you for this, astral traveler
        
           | temp0826 wrote:
           | As someone who has done a lot of both (as well as drank
           | ayahuasca several hundred times), they are completely
           | different animals especially at the full-dose levels.
        
             | turnsout wrote:
             | Several hundred times? There's a story there...
        
               | temp0826 wrote:
               | Maybe, maybe not. It's just life when you work at a
               | center :)
        
       | franze wrote:
       | I used that exact same image for ma Atkinson Dithering Algo
       | Learning Page https://atkinson.franzai.com/
        
       | _fat_santa wrote:
       | We need to push to make this stuff legal. I wouldn't go so far as
       | to say lets sell it OTC vape pens at gas stations but a middle
       | ground where you can go to a doctor to have this treatment
       | performed.
       | 
       | I personally have never taken DMT though from everything I've
       | read and heard on podcasts it's not something to be taken
       | lightly. I think having a sort of "DMT Clinic" that you can go to
       | would be the best middle ground of allowing the public access to
       | these substances while also ensuring that there is a trained
       | professional there to guide you through the process.
       | 
       | Saying "trained professional" in this context feels wired because
       | this stuff has been underground for so long but I think it's
       | starting to bubble up into the mainstream enough that we need to
       | start bringing all that "into the light". Lets have training
       | programs that teach people how to administer this stuff properly,
       | how to deal with the negative side effects, etc.
       | 
       | One of the things that while I find understandable is ridiculous
       | is the fact that Bill had to use a pseudonym in the community. I
       | feel like if were at the point where you have C-suite types at
       | Apple taking this stuff, it's time to think about making it
       | available to the broader public.
        
         | temp0826 wrote:
         | Fwiw, "DMT" usually refers to nn-DMT, which is a lot different
         | than 5-MeO-DMT (or bufo).
        
         | kelseyfrog wrote:
         | Agree, but the proponents of "Big Reality" _really really
         | really_ fight against its disruption.
        
           | pdabbadabba wrote:
           | Could you explain what you mean by that? Who are the
           | proponents of "big reality"? How do they fight against its
           | disruption?
        
             | gregschlom wrote:
             | It's a joke. People often have conspiracy theories about
             | Big Pharma trying to prevent access to novel drugs that
             | could disrupt their cash cows. The parent was jokingly
             | talking about "Big Reality" as an imaginary group of people
             | who hate to see "reality" disrupted by psychedelic
             | experiences.
        
               | colecut wrote:
               | I took it as being a joke in the way "the matrix" was "a
               | movie"
        
               | aeon_ai wrote:
               | When someone has a profound psychedelic experience that
               | shows them the arbitrary nature of many social
               | constructs, or reveals possibilities for consciousness
               | that mainstream science doesn't acknowledge... that's
               | genuinely disruptive to systems built on those
               | constructs.
               | 
               | The resistance is real, systematic, and rational (from
               | the perspective of maintaining current power
               | arrangements). Not a joke.
        
               | jonathanlb wrote:
               | I'm curious whether you think that resistance is
               | genuinely adversarial or more based on ignorance and
               | institutional inertia.
               | 
               | For example, someone might have insights about the
               | interconnectedness of all life and wants to transition to
               | regenerative agriculture or communal land use, but face
               | zoning laws that enforce individual property ownership.
               | Or someone might experience ego dissolution and wants to
               | create more egalitarian workplace structures, but runs
               | into rigid corporate hierarchies.
        
               | aeon_ai wrote:
               | Moloch devours breakthrough potential not through
               | conspiracy but through everyone rationally optimizing for
               | their individual/local situation while collectively
               | producing suboptimal outcomes.
               | 
               | Individual insight doesn't map to institutional action.
               | Systems can't integrate experiences they can't measure or
               | systematize.
               | 
               | I do think that there are _some_ truths to government
               | desire for narrative management, too. It is unwise to be
               | a hugger in a knife fight, and you don 't want the
               | populace to get high, see God, and deteriorate national
               | security.
               | 
               | All in all though, it all boils down to life being
               | complicated. The resistance isn't adversarial - it's
               | structural. Which makes it both less intentionally evil
               | and harder to overcome.
        
               | buildsjets wrote:
               | As RAW wrote in Cosmic Trigger: "Why does the gnosis
               | always get busted?"
        
             | kelseyfrog wrote:
             | Psychedelics challenge the post-Enlightenment project of
             | "rational" adulthood. Western civilization has a deep myth:
             | the myth of necessary order - a yoking of rationality,
             | order, and progress together into what forms the basis for
             | modernity. Psychedelics cannot have intrinsic value outside
             | of rationality, so, they must either be accepted on the
             | basis of rationality and order or face rejection. We
             | express this using the rational basis of improved mental
             | health. The contradiction of course is obvious;
             | psychedelics provide us with profoundly irrational
             | experiences that don't obviously fit into our cultural
             | value system.
             | 
             | The point is that western civilization values rationality,
             | order, and progress in a self-justifying way. The values
             | that our culture provides to us form a feedback cycle of
             | myth and virtue. Every argument that assumes this basis,
             | reinforces its truth.
             | 
             | "Order is _obviously_ preferable to chaos ", is one of many
             | subjective perspectives. Why should it hold more truth than
             | "Plurality of perspectives are obviously preferable to the
             | fragility of one perspective for the sake of objectivity"?
             | The apparatuses of the state[1] all rely on the same
             | cultural myth and promote it in a way that crowds out all
             | possible alternatives. Thus the myth of necessary order has
             | become synonymous with reality.
             | 
             | Like all deeply rooted cultural myths, this is something
             | that's going to appear obviously true which coincidentally
             | serves as a way of shielding it from honest critique. If
             | there's one thing that I've learned, it's that questioning
             | foundational myths feels like a cultural violation. Rene
             | Girard's theory holds; when a community is anxious or
             | unstable, it lashes out most viciously at people who
             | somehow threaten its central, but unspoken, truths or
             | anxieties. The greater the received response that a
             | cultural axiom obviously true; the more certain I am that
             | it reflects a core cultural myth than any semblance of
             | reality.
             | 
             | 1. See Louis Althusser, Ideology and Ideological State
             | Apparatuses, 1970.
        
           | rekttrader wrote:
           | That's an amazing sentence...
        
         | lukan wrote:
         | "I think having a sort of "DMT Clinic" that you can go to would
         | be the best middle ground "
         | 
         | Well, Ayahuasca (with DMT as the active ingredient) retreats
         | seem more and more common and are for some reasons tolerated
         | more and more in europe. Technically it is illegal, but I can
         | still book them online.
         | 
         | But I won't, as I don't trust the competence of the average new
         | age "shaman".
        
           | copperx wrote:
           | I dislike the idea of potential life threatening toxicity,
           | the constant vomiting, the feeling like shit for days.
           | 
           | Ayahuasca trips seem to be like edging with poison. But maybe
           | the documentary I saw was biased.
        
         | evmar wrote:
         | The state of Oregon is experimenting along these lines:
         | 
         | https://www.oregon.gov/oha/ph/preventionwellness/pages/psilo...
         | 
         | "A client may only access psilocybin at a licensed service
         | center during an administration session in the presence of a
         | trained, licensed facilitator."
        
           | hncomment wrote:
           | Oregon had gone with a broader decriminalization as of
           | February 1, 2021, but rolled that back in 2024:
           | https://en.wikipedia.org/wiki/2020_Oregon_Ballot_Measure_110
        
         | chrisweekly wrote:
         | "wired" -> weird
        
           | GuinansEyebrows wrote:
           | immediately jogged my memory for one of my favorite stupid
           | Simpsons moments:
           | 
           | "why, there's no magazine _called_ 'Weird' is there?" [0]
           | 
           | [0] https://www.youtube.com/watch?v=QjZ0GBL9ArA
        
         | mosburger wrote:
         | Last year I underwent treatments for my treatment-resistant
         | major depression using Ketamine. It was a clinical setting,
         | where you'd get wired up to blood pressure, pulse-ox, and other
         | monitors while you were monitored by an RN via video camera.
         | This was IV Ketamine, so not the inhalants that are available
         | now. According to the clinic, the inhalants (which they also
         | offered) are also generally less effective than IV, and the IV
         | was safer in my case because I have other medical conditions
         | where being able to "shut it off" was a good thing - you can
         | turn an IV off, but once you inhale, you're on your own.
         | 
         | So... this clinic was not entirely unlike what you're proposing
         | w/ DMT.
         | 
         | FWIW, the results were incredible. I was effectively "cured."
         | But unfortunately my insurance changed, and it became no longer
         | covered, and I couldn't afford the $2000 every six weeks for
         | the treatment anymore. And it's not super convenient to take
         | two hours off from work to go to the trip-sitter's to get the
         | treatments.
         | 
         | I hope that they figure out what it is in psychadelics that
         | make them effective at treating stuff like depression and PTSD
         | and make it more accessible because it seems like there's so
         | much potential there.
         | 
         | (Also: fuck Elon Musk for making Ketamine a punchline)
        
           | copperx wrote:
           | I like the potential healing value of Ketamine.
           | 
           | But that doesn't make replacing every instance of ketamine
           | with "horse tranquilizer" any less funny.
        
         | shpongled wrote:
         | N,N-DMT is very intense and not to be taken lightly - but you
         | could say the same with LSD, psilocybin, etc. Personally, I am
         | much more wary of large doses of LSD/psilocybin than DMT, in
         | part to the substantially longer duration of the former. Ego
         | death and the complete dissolution of reality makes it harder
         | to have a bad trip
        
           | gavinray wrote:
           | I'd generally agree with you, but:                 >
           | substantially longer duration of the former
           | 
           | When time stops until the end of this universe gives way to
           | the beginning of this universe and the snake eats it's tail,
           | "longer" doesn't hold much meaning...
        
             | shpongled wrote:
             | True, I should have qualified "actual" duration, not
             | perceived duration!
        
         | hncomment wrote:
         | A wise legalization might help with access & harm-reduction...
         | but legalizations are sometimes bungled.
         | 
         | In the SF bay area - & plenty of other regions around the world
         | - the criminal enforcement against hallucinogens is, de facto,
         | a very low priority as long as you're not flagrantly
         | endangering or inconveniencing others.
        
       | tiahura wrote:
       | I can't tell you the number of times I've thought that what this
       | country needs is more druggies running around.
        
         | criddell wrote:
         | More people like Bill Atkinson? That sounds good to me.
        
         | knowaveragejoe wrote:
         | How can you look at this and think "druggies"?
        
         | jobs_throwaway wrote:
         | More people like Bill Atkinson and Steve Jobs sounds great to
         | me!
        
         | edm0nd wrote:
         | these are the 'good' type of drugs though
        
       | damnesian wrote:
       | Am I the only person who read the article like this: "blah blah
       | BOTH BILL ATKINSON AND STEVE JOBS DIED FROM PANCREATIC CANCER
       | blah blah"?
        
         | duckbot3000 wrote:
         | Steve Jobs tried to treat his cancer by eating apples and
         | ignoring the diagnosis until it was too late... not sure if
         | that's really connected to psychedelics
        
       | wvlia5 wrote:
       | I'm developing a much more advanced digital device (like bicycle
       | to spaceship compared to this). I'm currently blocked by
       | chemistry issues.
        
       | nonelog wrote:
       | While DMT definitively has its merits (and is produced naturally
       | in the human body), know also that Psilocybin allows for an
       | increases of the human lifespan of over 50%, which is absolutely
       | massive. [0]
       | 
       | It's entirely natural, easy to do, has no side effects, costs
       | next to nothing, and can even be "fun". As usual, the media will
       | not talk about this discovery, as it is too much of a game-
       | changer for our current systems.
       | 
       | [0] https://neurosciencenews.com/psilocybin-longevity-
       | aging-2942...
        
         | ashalhashim wrote:
         | I assume this comment is trolling. But to be clear to readers,
         | the link states psilocybin 50% increase in lifespan of human
         | skin etc. not human lifespan.
        
           | nonelog wrote:
           | "[...] extended the cellular lifespan of _human skin and lung
           | cells_ by more than 50% "
           | 
           | If we assume that the effect is the same for all types of
           | cells, it follows that the life is extended by 50% (when
           | keeping "all other factors" constant, as usual).
        
             | nick__m wrote:
             | It has to also down-regulate cells divisions, else it could
             | be quite problematic.
        
       | demaga wrote:
       | I feel like someone is trying really hard to push public
       | perception of psychedelics towards "acceptable". I don't know who
       | it benefits, but this is a really weird Overton window.
       | 
       | I wouldn't say a word if it weren't nth article about
       | psychedelics that appears on HN frontpage. I was quiet the last
       | n-1 times.
       | 
       | If you google psilocybin right now, you can see articles that
       | state how it "slows ageing" and "cures depression". There
       | probably is some truth to it, but only in very specific sense and
       | specific circumstances. Most people will NOT benefit from taking
       | the drug (as with any drug).
       | 
       | So it hurts my soul when I see words like "legalize" being thrown
       | in this context. We know very very little about effect of such
       | drugs. And the goal should not be to legalize, but rather to
       | expand our knowledge on how it works, and create safe medicine
       | that actually helps people.
       | 
       | Rant is over now. Thank you.
        
         | kloop wrote:
         | > So it hurts my soul when I see words like "legalize" being
         | thrown in this context. We know very very little about effect
         | of such drugs.
         | 
         | That seems like exactly when we should legalize it. The default
         | is legal, and without definite knowledge of serious harm, that
         | should be the status.
         | 
         | The burden of proof should be on the people who want it to be
         | legal, and by your comment, their case seems pretty weak.
        
           | 1718627440 wrote:
           | Sure, just let people use any weapon, we don't know for sure,
           | if any particular bullet is mortal, maybe they don't cause
           | any harm that time.
        
         | pazimzadeh wrote:
         | It's a lot easier to study if it's legal. It's also pretty hard
         | to come up with a convincing placebo. The experience is also
         | highly colored by "set and setting", and the clinical
         | environment or office space is probably not ideal for this
         | knowledge expansion..
         | 
         | An article just came out showing that psilocybin extends life
         | in aged mice, so that's why you're seeing it a lot. Yet we have
         | no idea what causes this lifespan increase. Is it a result of
         | "hallucination" experience itself , a purely chemical effect,
         | or something in between? (aka will a 'bad trip' give the same
         | effect on lifespan?)
         | 
         | > Most people will NOT benefit from taking the drug (as with
         | any drug)
         | 
         | Now you're just making things up.
        
         | hnthrowaway0315 wrote:
         | That's something I'm really worried about, especially when SV
         | is pushing it. And it is difficult to prove that research is
         | unbiased.
         | 
         | One of the commenters of your post says "If we legalize it we
         | can better research it". Allow me to be rude -- this is BS. If
         | we follow this logic we should legalize pretty much everything!
         | 
         | I think it is polite to be rude to such dangerous thoughts.
         | Downvote me as you see fit.
        
           | allears wrote:
           | But following your logic everything would be illegal! There's
           | a whole lot we don't know about how aspirin works, for
           | instance.
           | 
           | Governments should not be in the business of banning things
           | unless there's a clear and present danger. Citizens should
           | have the autonomy to do risky things if they want to.
        
             | nick__m wrote:
             | Aspirin mechanisms is known since the late 1970s, it's a
             | COX inhibitor.
             | 
             | Acetaminophen is the one that still mysterious, there are
             | credible theories but they don't explain everything the
             | substance does. The latest one I know of is that one :
             | https://www.pnas.org/doi/10.1073/pnas.2413811122
        
           | justinrubek wrote:
           | I think a blanket ban under schedule 1 stating that it has no
           | acceptable use is dangerous. It's a clearly false designation
           | and doesn't have evidence to back it up. This isn't a simple
           | matter of a dangerous substance. This is a hard-core human
           | rights violation.
        
       | notarobot123 wrote:
       | Related: Hypercard was inspired by an LSD trip which Bill
       | explains in an interview
       | (https://www.youtube.com/watch?v=bdJKjBHCh18)
        
         | DonHopkins wrote:
         | HyperCard and Timothy Leary's Mind Mirror would be a match made
         | in heaven!
         | 
         | Timothy Leary's Mind Mirror (1985) (usc.edu)
         | 
         | https://scalar.usc.edu/works/timothy-leary-software/index
         | 
         | https://news.ycombinator.com/item?id=32578683
         | 
         | https://www.youtube.com/watch?v=9oabRxvjf9k
         | 
         | I extracted all the text and data from the Apple ][ floppy
         | disk:
         | 
         | https://news.ycombinator.com/item?id=37486524
         | 
         | https://donhopkins.com/home/mind-mirror.txt
         | 
         | https://github.com/SimHacker/lloooomm/tree/main/00-Character...
        
       | brainless wrote:
       | I am on the fence with these topics because I have years of fear
       | drilled into me. These topics are a taboo and I have rarely ever
       | tried anything at all. The experiences did not ruin me, they made
       | me more curious about my brain in a positive way. But the social
       | taboo lingers.
       | 
       | What surprises me the most is that we have accepted sugar,
       | alcohol, cigarettes and a ton of mass manufactured food which are
       | harming us. I am struggling with high blood glucose for 12 years.
       | Yet, the substance which I can grow in my* own backyard and may
       | actually not be as harmful is just brainwashed out of my limits.
       | 
       | edits: you to me
        
         | zoklet-enjoyer wrote:
         | Is there that much of a social taboo? Maybe it's just the
         | people I hang out with and work with, but most people are open
         | to psychedelic use and a lot have at least tried some.
        
           | skyyler wrote:
           | Some people's conception of "normal people" is people on the
           | bus or train.
           | 
           | Some people's conception of "normal people" is people at a
           | church ice cream social.
           | 
           | Different perspectives, I think.
        
           | lelandfe wrote:
           | Yes, it's your bubble. There are American states still
           | charging people over marijuana. Having grown up Christian I
           | personally know people in their 30s who view psychedelic and
           | _heroin_ users similarly. Those people would have the
           | opposite view of you.
           | 
           | Years back, my friend's parents asked me to stage an
           | intervention for him after they found out he regularly took
           | LSD. He was 19 at the time.
        
             | zoklet-enjoyer wrote:
             | I live in a Republican state where marijuana is illegal
        
               | humpty-d wrote:
               | Farm bill and delta-8 really flipped that whole table
               | though
        
               | zoklet-enjoyer wrote:
               | Yeah, but our legislature banned that too
        
               | marcelox86 wrote:
               | Texas? :(
        
             | dudeinjapan wrote:
             | Growing up my friend's dad was a conservative christian and
             | a frequent caller into conservative talk radio shows. There
             | was a state referendum to legalize marijuana, so I asked
             | what he thought. "Of course it should be legal. It says
             | right there in Genesis--God said: I give you every herb
             | bearing seed upon the Earth. What could be more clear-cut
             | than that?"
        
         | stego-tech wrote:
         | As a similar "Boy Scout" of sorts, the fear is/was real. I
         | didn't experiment with so much as nicotine or alcohol until I'd
         | tried "stuff" with the supervision of an experienced "sitter";
         | I ended up having some of the best times of my life in the
         | safety and context of home and friendships. Combined with my
         | own life experiences with drug abuse and addictions, I was able
         | to build a healthy relationship with those substances that
         | didn't result in dependency or abuse.
         | 
         | In the time since, my views have changed dramatically on these
         | substances, and I'd like to try more of them. However, my
         | personal moral compass prevents me from using substances
         | outside of a legally permissible setting, at least at present -
         | and that's something I'm fine with.
         | 
         | Ultimately, the taboo side of things is something the
         | individual has to grapple with on their own. I can only
         | commiserate with your frustrations, not help overcome them
         | unfortunately. My only other advice would be to use _any_
         | substance only to amplify good vibes, never to cope with bad
         | ones.
         | 
         | If all you do is chase a lost feeling, you're missing out on
         | what's in front of you now.
        
       | jekwoooooe wrote:
       | Without rigorous science and licensed professionals it would be
       | insanity to take these drugs. They can potentially PERMANENTLY
       | traumatize your brain possibly even _literally_ ruining your
       | entire life. I guess that risk is worth it for some people
        
         | Ylpertnodi wrote:
         | Your concern is warranted, but a tad hyperbolic. Getting into
         | a[n even minor] car crash, and thereafter recovery, can have
         | equally devastating effects, as can being attacked by a dog.
        
         | justinrubek wrote:
         | [flagged]
        
           | dang wrote:
           | Can you please express your substantive points without
           | getting personal? I'm sure you didn't intend to cross into
           | personal attack but this comment is a step in that direction.
           | 
           | https://news.ycombinator.com/newsguidelines.html
        
         | bongodongobob wrote:
         | I used to be very active in the hippy music scene. Permanent
         | effects are exceedingly rare. I know people who trip fairly
         | frequently and beyond some dreadlocks or tie dyed shirts off
         | the clock, they are perfectly normal well adjusted people. You
         | are being extremely hyperbolic.
        
         | wtetzner wrote:
         | I mean, so can alcohol.
        
       | hnthrowaway0315 wrote:
       | I'm skeptic about psychedelic. Is there enough unbiased research
       | about these stuffs? I myself is interested in it too but so far
       | it is in general illegal in Canada, and I don't consider myself
       | knowledgeable enough to try it out.
        
         | nick__m wrote:
         | there are plenty of psychedelics legal in Canada, I know of a
         | few chemical suppliers that specialize in this. It's been at
         | least a decade since I last ordered from them, but they are
         | still in bussines.
         | 
         | However you said that your not knowledgeable and I guess that
         | you doesn't have access to a milligrams scale, so your better
         | to stay away and learn the theory first. A lot of psilocybin
         | analog (alpha-MethylTryptamine was one of my favorite and it's
         | still available) from Thikal are still legal in Canada so that
         | book is a good place to start learning.
        
         | xsmasher wrote:
         | There is not enough research because, at least in the US, there
         | was a blanket ban on any research since 1970 when most
         | psychedelics were placed on "Schedule I" - meaning they had "no
         | accepted medical use" and "high potential for abuse."
         | 
         | "Big Reality" was either terrified of everyone becoming
         | drooling monkeys, or people seeing behind the curtain of
         | society, depending on who you ask.
        
       | dare944 wrote:
       | Off-topic, but I have to...
       | 
       | (From the photo caption) "Bill ... with his iphone prototype"
       | 
       | Nope. That's a Sony Magic Link, built by Bill (and others, myself
       | included) during his time at General Magic. I feel General Magic
       | is another one of Bill's endeavors that isn't widely understood
       | or appreciated.
        
         | radicaldreamer wrote:
         | There was a great documentary on Magic Leap!
         | https://www.generalmagicthemovie.com
        
           | Stratoscope wrote:
           | That is a great documentary, but it's about General Magic,
           | not Magic Leap.
           | 
           | https://en.wikipedia.org/wiki/General_Magic
           | 
           | https://en.wikipedia.org/wiki/Magic_Leap
        
           | dare944 wrote:
           | Yep. I can be seen briefly in one scene, listening intently
           | in the background while Marc Porat waxes poetic.
        
           | piyiotisk wrote:
           | This is my favourite documentary on tech! If you know more
           | please let me know
        
         | yyzaxle wrote:
         | Hi there. I will correct the iPhone prototype reference. Thanks
         | for the heads up. - Axle / www.patternproject.ca
        
         | piyiotisk wrote:
         | Who are you sir? I am a big fan of the general magicians
        
           | dare944 wrote:
           | My name is Jay. I guess I was one of the "lesser" magicians.
           | I worked on the Telescript side, doing infrastructure for the
           | Telescript engine. But I got to interact with both Bill and
           | Andy, and Phil and Tony, who I followed to further ventures.
           | My experience at General Magic was certainly eye opening and
           | super educational.
        
       | nsxwolf wrote:
       | What if "dissolving the ego" is bad though?
        
         | allears wrote:
         | Thousands of years of Buddhist practice says it isn't
        
         | Synaesthesia wrote:
         | Psychedelics are not some harmless cure-all. They can provide
         | remarkable experiences, life affirming experiences and being
         | quite effective against depression. They can also cause some
         | pretty scary and bad times. So they need to be treated with
         | respect. But I think they're well worth exploring.
        
       | esseph wrote:
       | I hope research with psilocybin, DMT, and other psychedelics
       | continue and that some of these possible discoveries pan out.
       | 
       | Example that just came across my news feed: "psilocin, a
       | byproduct of consuming psilocybin, the active ingredient in
       | psychedelic mushrooms, extended the cellular lifespan of human
       | skin and lung cells by more than 50%."
       | 
       | https://neurosciencenews.com/psilocybin-longevity-aging-2942...
        
       | kmoser wrote:
       | > His open-source approach democratized psychedelic exploration,
       | shifting power away from costly retreats and elite gatekeepers
       | toward broader accessibility.
       | 
       | No surprise that, in keeping with the hacker spirit, Bill wanted
       | to democratize information that is otherwise accessible only to
       | "high" priests.
        
         | trenbologna wrote:
         | If you have ever had the experience you will want to share with
         | the world and give everyone the opportunity to experience it.
        
           | ComplexSystems wrote:
           | Is this different from regular DMT?
        
       | ge96 wrote:
       | People talk about getting out of software and doing woodwork Now
       | this... I've actually done DMT one time was crazy and instant the
       | effects but brief. I did it at a dining room table with wooden
       | grain and concentric ring placemats. I remember seeing my arm
       | like wtf is that. And then the grain/rings moving. Even closing
       | my eyes I'd see colors but was over in a couple minutes.
       | 
       | What I had my friend made. Bought some root, had to use naptha to
       | separate it in a fridge then put it (powder) on top of something
       | flammable and smoke it like weed.
       | 
       | Further thoughts:
       | 
       | On a side note/comparison, weed for me it's like. Day to day
       | you're driven by a known process/system. You have to get to work
       | at 9 AM, go to this, then that. Smoking weed you stop and are in
       | the moment, suddenly focused on how vibrant this red shrub is
       | that you normally ignore. I don't smoke weed anymore because it
       | makes me super paranoid like afraid cops are going to arrest me
       | or I can't interact with people as I already have social anxiety.
       | The other thing is it would enforce my delusions thinking some
       | idea was great/fixate on some design (I was trying to use it to
       | come up with ideas to make money).
       | 
       | DMT is like losing steady state/reality, solid things start to
       | move. The colors were not solid for me, it's like when you push
       | your eyes (while closed) and you see flashes of light. This was a
       | long time ago I did it so might not be remembering as well, it
       | was intense though and brief.
       | 
       | I have not done acid or shrooms as I have bad repressed childhood
       | memories and I don't want to get stuck in that for hours.
       | 
       | Did K one time, I just sat on a couch throughout a party doing
       | nothing/sipping on a cup of water.
       | 
       | K2/Salvia that stuff was whack, I felt like I was sinking into a
       | couch when I smoked it in a shed with a buddy and I felt dumb
       | like I couldn't talk correctly.
       | 
       | C and Addy, amazing. I mean if you could operate life like that
       | all the time you'd probably die just because you'd do crazy
       | things like do a jump that you normally wouldn't just because of
       | the overconfidence. But yeah the ability to sit down/cram 12 hrs
       | of work and pass a test, amazing or nail every note on a guitar.
       | The weight loss is great but I found my p would shrink so much it
       | was crazy. At one point started to defecate blood (was just a
       | fissure) so yeah that was a problem. I would use A for times when
       | I couldn't get sleep and would just do these overnighters at a
       | data-entry job.
       | 
       | Also did M before (fake addy) and yeah, that's great for
       | drinking, you can just pound beers/liquor and not feel it. The
       | bad thing is the come downs, you are drained of happiness, can't
       | do anything and it is hard to recover. A way to recover is to
       | jerk off a lot. But yeah I don't do that anymore just because the
       | sadness is crazy.
        
         | hncomment wrote:
         | Note that 'DMT' isn't a shortened name for '5-MeO-DMT'. While
         | related, 'DMT' and '5-MeO-DMT' are different compounds, with
         | different effects:
         | 
         | https://en.wikipedia.org/wiki/5-MeO-DMT#Effects
         | 
         | https://qualiacomputing.com/2020/07/01/5-meo-dmt-vs-nn-dmt-t...
        
         | ge96 wrote:
         | I don't partake anymore, only drink nowadays and even that try
         | to only do a day a week since it costs money but also I don't
         | actually enjoy the taste of alcohol. I use it for the social
         | aspect but then I do too much of it and do dumb things like
         | climb buildings or try to fight people, go to strip clubs drop
         | money I don't have. (I spent $1.2K one time it's bad since I go
         | out to try and meet women)
         | 
         | My other drug of choice is adrenaline from driving fast my car
         | currently tops out just under 160mph and I'd go even faster if
         | I could but maybe thankfully I can't. Fear is funny too, I
         | don't fear this but I fear talking to people ha.
         | 
         | I'm trying to stop this because the tickets part, I only screw
         | around on highways when I'm alone and day time, I don't do
         | swimming/cutting people off but yeah.
         | 
         | The speed thing is easy get an old ZR1 it can go 200 but going
         | in a straight line can be boring. It's the acceleration.
         | Recently been watching this guy drive an Elise down roads in
         | Switzerland that's pretty fun and not that fast. I know you can
         | track too but idk.
        
       | kragen wrote:
       | Is the world's most powerful psychedelic the personal computer,
       | or is it 5-MeO-DMT (Jaguar)? Not having tried the latter, and
       | therefore speaking from a position of ignorance, I'm inclined
       | toward the former. I think Timothy Leary agreed with me.
        
         | dpc050505 wrote:
         | Having experience with a lot of psychedelics it's completely
         | ridiculous to put the personal computer in that category.
         | 
         | Timothy Leary might've drawn a parallel on the psychological
         | impact of computers (I have no idea on the exact quote or it's
         | context), which is enormous, but computers are just not
         | psychedelic.
        
       ___________________________________________________________________
       (page generated 2025-07-11 23:00 UTC)