[HN Gopher] US FDA approves Gilead's twice-yearly injection for ...
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US FDA approves Gilead's twice-yearly injection for HIV prevention
Author : JumpCrisscross
Score : 35 points
Date : 2025-06-18 19:39 UTC (3 hours ago)
(HTM) web link (www.reuters.com)
(TXT) w3m dump (www.reuters.com)
| hughw wrote:
| Who will take this drug? Every sexually active person? Would
| insurers pay for prophylaxis?
| mystified5016 wrote:
| Insurance (at least some) do pay for oral HIV prophylaxis (in
| the US)
| hyperhello wrote:
| Couples with one infected partner, I suppose.
| foxyv wrote:
| I can think of a few cases where this would be a good idea. IV
| drug users, those engaging in risky sex, sex workers, hospital
| workers after accidental exposure, HIV positive mothers, those
| with drug resistant HIV, people with HIV positive partners, and
| anyone who cares to.
| toomuchtodo wrote:
| Anyone at risk of exposure.
|
| https://hivinfo.nih.gov/understanding-hiv/fact-sheets/pre-ex...
| hughw wrote:
| thanks for that link.
|
| _if you are HIV negative, have had anal or vaginal sex in
| the past 6 months, and:_ Have a sexual
| partner with HIV (especially if the partner has an unknown or
| detectable viral load), or Have not consistently used a
| condom, or Have been diagnosed with a sexually
| transmitted infection (STI) in the past 6 months.
|
| This is a very, very high number of candidate patients!
| Anyone who inconsistently uses a condom. "During 2011-2015,
| 14.8 percent of women and 19 percent of men aged 15-44
| reported that they used a condom 'every time' they had
| intercourse in the past 12 months," the NCHS team wrote in
| their report." [1]
|
| [1] https://www.nbcnews.com/health/health-news/third-u-s-men-
| use...
| toomuchtodo wrote:
| A wide net can be cast, but broadly speaking, you'll want
| to start with your highest exposure and compliance (having
| to take a pill everyday is not great) risk patients first
| and work your way down as you scale up manufacturing and
| last mile infrastructure. Daily pill users turn into twice
| annual injection users, healthcare workers who could
| receive the injection at the workplace, etc.
|
| This should, in theory, cause the infection rate to rapidly
| decline when you disrupt the most common and frequent
| transmission vectors. The slow long burn is going to be
| upkeep on all of this until HIV is eradicated (similar to
| the last days of a disease due to sufficient vaccination
| uptake, think smallpox).
| HWR_14 wrote:
| My guess is that it's cost effective to pay for prevention.
| JumpCrisscross wrote:
| The social case for heavily subsidising (if not making free)
| preventative care and treatment for _any_ contagious disease
| is strong.
| nerdjon wrote:
| This is awesome news, with a lot of the recent news I was worried
| this was not going to happen or we would get some stupid fear
| mongering (or some puritanical reason used).
|
| Now the real question is insurance. Is this cheaper than the
| pills?
|
| To my knowledge even the previous injections were hard to get
| insurance to pay for given how cheap you can get truvada since
| its generic.
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