[HN Gopher] How the Alzheimer's Research Scandal Set Back Treatm...
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How the Alzheimer's Research Scandal Set Back Treatment 16 Years
(2022)
Author : walterbell
Score : 37 points
Date : 2025-06-13 21:53 UTC (1 hours ago)
(HTM) web link (www.discovermagazine.com)
(TXT) w3m dump (www.discovermagazine.com)
| abetancort wrote:
| Old and outdated.
| djoldman wrote:
| Derek Lowe's take:
|
| https://www.science.org/content/blog-post/reaction-alzheimer...
| wileydragonfly wrote:
| Which is the only good take... if there wasn't "something
| promising" with the idea, people wouldn't have kept at it.
| There's only so much time you're going to waste on pure fantasy
| before you move on. The whole ordeal had me quite upset as I
| was supporting studies looking at this, and the patients are
| beyond desperate for any treatment. None of us got rich.
| throwawaymaths wrote:
| he was not in the trenches in 2003. in 2003 we were working in
| an Alzheimer's lab and everyone in our lab at least was
| expressing suspicion that there was something wrong with the
| hypothesis. pretty much every internal lab meeting started with
| "the amyloid hypothesis is... [this statement exists because
| our funding stream] though it is not conclusively proven, wink
| wink"
| PaulKeeble wrote:
| Its not the only disease this has happened to either. ME/CFS has
| been railroaded by European governments that funded only
| psychological research despite numerous pathological findings and
| better theories of the disease, this prejudiced treatment started
| in the 1970s and persists to this day including the corruption of
| the PACE trial results which researchers tried to hide the data
| of.
|
| Research fraud in medicine is alarmingly common.
| Henchman21 wrote:
| There's money to be made; don't let facts stand in the way of
| profits!
| Centigonal wrote:
| This argument gets invoked a lot when it comes to medical
| dishonesty, but I really don't think it applies in the case
| of ME/CFS. If we could find the pathology behind the
| condition, there is huge money to be made in pharmaceutical
| treatments. Just look at the enormous amount of money being
| made treating auto-immune illnesses with
| Humira/Skyrizi/Xeljanz/etc, treating diabetes with GLP-1
| agonists and CGMs, and treating obesity with GLP-1 agonists
| (and depression before all that!). Sometimes treating the
| chronically ill is the most profitable option.
| fnordpiglet wrote:
| This is from 2022
| seltzered_ wrote:
| Related articles:
|
| - The great brain clearance and dementia debate -
| https://www.nature.com/articles/d41586-025-00962-y (2025)
|
| - The Devastating Legacy of Lies in Alzheimer's Science -
| https://www.nytimes.com/2025/01/24/opinion/alzheimers-fraud-...
| (2025), referencing the book Doctored
| https://en.m.wikipedia.org/wiki/Doctored_(book)
|
| - The maddening saga of how an Alzheimer's 'cabal' thwarted
| progress toward a cure for decades -
| https://www.statnews.com/2019/06/25/alzheimers-cabal-thwarte...
| (2019, by the late Sharon Begley)
| robwwilliams wrote:
| Great and highly critical book on this general topic: "How Not to
| Study a Disease" by Karl Herrup from MIT Press:
|
| https://direct.mit.edu/books/book/5216/How-Not-to-Study-a-Di...
|
| The core problem is much older than stated in this focused
| review.
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(page generated 2025-06-13 23:00 UTC)