[HN Gopher] Engineers develop wearable heart attack detection te...
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       Engineers develop wearable heart attack detection technology
        
       Author : PaulHoule
       Score  : 65 points
       Date   : 2025-05-07 17:32 UTC (4 days ago)
        
 (HTM) web link (medicalxpress.com)
 (TXT) w3m dump (medicalxpress.com)
        
       | krunck wrote:
       | How do you get a decent ECG with a wearable that has a single
       | point of contact with the skin. If you need to touch a contact on
       | the device to get a two lead equivalent ECG then how can this be
       | real time monitoring?
        
         | ashwinsundar wrote:
         | Real-time monitoring and continuous monitoring are different
         | goals. The use case for something like this is probably a
         | wearer who is experiencing heart palpitations, and has the time
         | and clarity of thought to actually find the correct app on
         | their device and start recording.
         | 
         | Continuous monitoring is extremely challenging still because
         | ECG data needs to be sampled at a relatively high frequency
         | (~200 Hz) to accurately identify the QRS complex in the
         | waveform. That uses a lot of power, and the batteries we have
         | still aren't good enough to support those types of demands. 200
         | * 60 * 60 = 720,000 samples per hour to collect and process.
         | 
         | It's possible that algorithmic approaches may be able to reduce
         | the sampling frequency required. Power-constraints were the
         | main issue when I studied this topic 10 years ago during my
         | master's degree. I had looked into non-frequency domain
         | techniques (such as empirical mode analysis/Hilbert-Huang
         | transform) as a possible way to reduce sampling frequency and
         | thus power consumption.
         | 
         | https://github.com/AshwinSundar/Empirical-Mode-Decomposition...
        
           | sneak wrote:
           | i would imagine you could take an ekg for 1-2 seconds every
           | 30 seconds and run it through a much more simple model to
           | determine if it should take a longer sample, no?
           | 
           | rather than reducing the frequency of the sampling,
           | dynamically adjust the duty cycle of when sampling is
           | happening?
           | 
           | this is probably a dumb suggestion, it seems pretty obvious.
           | for example the apple watch doesn't do o2 monitoring
           | continuously, just for some fraction of the time.
           | 
           | do you need to sample every second to detect heart attacks?
           | don't they continue to show up on an ekg for more than 30
           | seconds?
        
             | elric wrote:
             | > apple watch doesn't do o2 monitoring continuously, just
             | for some fraction of the time
             | 
             | Making it effectively useless? Unless the fraction of the
             | time is multiple times per minute? E.g. in sleep apnea it's
             | not uncommon for some desaturation to occur, triggering an
             | arousal and deeper breaths, restoring saturation, only for
             | the cycle to repeat 2 minutes later.
             | 
             | My Garmin has a similarly useless feature. I have no idea
             | what the supposed benefit is. Maybe they hope that if they
             | sample multiple nights they can detect some desaturation
             | anyway and can get the user in for polysomnography? Might
             | be worth it.
        
               | jml78 wrote:
               | I have mild sleep apnea and my Apple Watch is the reason
               | I figured it out. If you wear it every night, you will
               | catch it. I have on average 1-2 events an hour. Even with
               | that few, the Apple Watch would catch the O2 drop enough
               | times over a month that it worried me to see my O2 drop
               | under 90%
        
           | firesteelrain wrote:
           | Fitbit supports detection of Afib and has FDA approval. It's
           | not entirely out of the realm of possibility that one day it
           | could also receive approval to detect heart attacks. It
           | probably already has the data that might lead a savvy user to
           | infer it just by looking at elevated resting heart rate, SpO2
           | differences, and irregular heart rhythm alerts.
        
             | lazyasciiart wrote:
             | My Fitbit record showing heart rate spikes to 125 was one
             | of the things that I noticed that suggested I was having a
             | heart attack in 2020 (I was).
        
               | stavros wrote:
               | Hm, why is 125 a heart attack? Isn't that a fairly normal
               | heart rate for exertion? Or were you just at rest?
        
               | firesteelrain wrote:
               | GP could have been having a non STEMI heart attack.
        
               | lazyasciiart wrote:
               | I was, actually, but I don't know how that's connected?
               | This was something like a ten minute spike in the middle
               | of the night, a couple of times.
        
               | firesteelrain wrote:
               | The sympathetic nervous system activates, increasing
               | heart rate and the body is trying to compensate for the
               | compromised heart muscle. Then, there is the possible
               | adrenaline surge because you are actually in pain. If the
               | NSTEMI causes left ventricular dysfunction, the heart
               | compensates with a faster rate to maintain blood flow.
               | 
               | I went through this with a relative just two weeks ago
               | and learned this from the cardiologists
        
               | lazyasciiart wrote:
               | I was lying down at rest.
        
           | vlovich123 wrote:
           | There are audio recorders like TileRec by Attodigit that can
           | record for 30 hours on a single charge and voice is recorded
           | at 16khz and compressed live to mp3 and is super tiny at
           | 0.5z. I'm thoroughly unconvinced that power or complexity of
           | handling a 200hz signal is the bottleneck. 200hz is nothing
           | probably even to a low end microcontroller these days.
        
           | hwillis wrote:
           | This is out of my specific expertise, but the AFE1291 does 8k
           | 24 bit samples per second and uses 495 mW when sampling.
           | That's enough to run full rate for 10 straight days on an
           | apple watch battery (1.189 Wh was the first google result).
           | 
           | Integrated frontends have had big impacts on efficiency and
           | improving batteries have had basically the same increase in
           | specific energy. I would be shocked if power was a limiting
           | factor.
           | 
           | https://www.ti.com/lit/ds/symlink/ads1291.pdf?ts=17469713549.
           | ..
        
         | avs733 wrote:
         | There's a strong history of useful signals from single lead
         | ecgs.
         | 
         | Detection of ecg anomalies(especially episodic ones with
         | intermittent recording) was the subject of the physionet
         | cardiac computing challenge almost 10years ago[0].
         | 
         | It's amazing how far machine learning has come. I know teach a
         | version of this challenge as a one day in class activity in my
         | department's physiology class. They actually get to train
         | multiple models on a gpu cluster (and compare that to trying to
         | train models on their laptops).
         | 
         | One thing we reinforce in the lesson is human vs. computer
         | "interpretation". They/clinicians can look at ecgs and make
         | some sense of them. An LTSM is worse than random chance/a
         | medical student. However moving to the frequency domain makes
         | the LTSM more accurate than cardiologists, but neither they nor
         | clinicians can "see" afib ina spectrograph. It's a great way to
         | talk about algorithmic versus human reasoning and illustrate
         | that to students.
         | 
         | That then gets reinforced with other case studies of the ying
         | and yang of human and machine decision making throughout our
         | curriculum- like alpha fold working great until you ask it
         | about a structure in the absence of oxygen, because that's not
         | in its training data.
         | 
         | [0] https://physionet.org/content/challenge-2017/1.0.0/
        
           | closewith wrote:
           | > There's a strong history of useful signals from single lead
           | ecgs.
           | 
           | But to be clear, a single lead ECG requires two electrodes at
           | a minimum and commonly a third as ground. So a single lead
           | ECG will have minimum two cables attached to electrodes on
           | the patient. The placement depends on which lead (eg lead I,
           | lead II, etc) but there's always two minimum.
        
       | elric wrote:
       | Article seems very light on details. Is this trying to detect ECG
       | markers of heart attacks (like ST segment issues)? Is it somehow
       | detecting troponin in the blood stream? How? And how are they
       | going to prevent false positives if this is indeed a wrist-based
       | device as I imagine it will be?
        
         | user_7832 wrote:
         | It seems to be using ECG, the (correct) springer link is
         | https://link.springer.com/chapter/10.1007/978-3-031-82377-0_...
        
           | elric wrote:
           | Can't read the full article. Abstract mentions 92% accuracy.
           | That could be abysmal depending on how it's calculated?
           | Correctly identifying 92% of heart attacks and missing 8%
           | might be pretty good. But reporting false positives 8% of the
           | time would be awful.
        
             | bobmcnamara wrote:
             | Even 'return false' would best 92% accuracy.
        
               | closewith wrote:
               | Yes, global afib prevalence is about 1-2%, so return
               | false would be 98-99% accurate, which is why accuracy is
               | not a metric used to assess medical diagnostics.
               | 
               | However, the sensitivity of return false is 0%, which
               | renders it useless (and why sensitivity and specificity
               | are used in this context).
        
             | absolutelastone wrote:
             | I suspect it's probably worse than that in reality. From a
             | quick search on state of the art ECG results (the full
             | system of leads attached all over your torso) it looks like
             | around 90 percent specificity (True negative rate) and
             | under 50 percent sensitivity (true positive rate). So it's
             | only pretty good at ruling out heart attacks, but still
             | misses them sometimes. But is pretty bad when it comes to
             | false alarms. I think they use it along with multiple other
             | tests and consideration of symptoms in triage at the
             | hospital.
        
       | ETH_start wrote:
       | This kind of technology has been technologically viable for
       | decades. The fact that we're only now seeing prototypes, not mass
       | adoption, is an indictment of the legal framework around medical
       | devices.
       | 
       | The FDA classifies these devices as high-risk because they might
       | give a false result but completely ignores the guaranteed harm of
       | not having them at all. It's a system that punishes action and
       | rewards delay.
        
         | dennis_jeeves2 wrote:
         | >is an indictment of the legal framework around medical
         | devices.
         | 
         | Well medical devices aside, the legal framework around
         | anything, including business, manufacture etc. is more impeding
         | while failing to address things like environmental
         | destruction/pollution which causes real harm. ( notice, that I
         | did not say climate change, a separate subject).
         | 
         | It all makes sense when one sees it either though the lens of
         | either corruption of more likely human stupidity - where a
         | bunch of rules give people the comfort of being protected.
        
         | avalys wrote:
         | There's no "might" here, in a device advertised as "92%
         | accuracy". This device _will_ give false results, almost
         | certainly an overwhelmingly number of false results relative to
         | the actual heart attacks it detects. And those false results
         | have real, guaranteed harm and cost as well.
         | 
         | Both false positives and false negatives are harmful. False
         | positives will send people to the hospital for no reason and
         | divert resources from people with real emergencies - not to
         | mention leaving them with a large ER bill to pay. False
         | negatives will result in people with actual heart attacks
         | dismissing their symptoms and dying.
        
           | vlovich123 wrote:
           | The counter is that people can build their own informed
           | intuition about whether these things are helpful,
           | particularly in coordination with their doctor and experience
           | of using it. And a product is easier to improve and will
           | improve more quickly if the company can easily bring updates
           | and find investment that improve quality to product they have
           | revenue for.
           | 
           | I think the FDA safety margin for things like this should be
           | more "this has no actual obvious harm to use, it has a
           | plausible mechanism of action to help + isn't fraudulently
           | measuring what it claims to measure and its science backed.
           | 
           | Something like this hits all the targets already.
        
         | absolutelastone wrote:
         | I agree the legal restrictions (and liability) should be
         | looser. But other countries are pretty bad about this too in my
         | experience. It's more of a medical establishment monopoly thing
         | it seems.
         | 
         | Also you can already buy home ECG devices for a couple hundred
         | bucks. Not sure if there is some history of being banned in the
         | past or whatever, but otherwise I'd guess the main problem is
         | just a lack of much interest in the market.
        
         | hwillis wrote:
         | What is burdensome about the regulations? They are here:
         | https://www.fda.gov/medical-devices/guidance-documents-medic...
         | 
         | They allow a summary report. They don't require a clinical
         | human trial. They barely care if you follow the FCC and safety
         | requirements for electronics in general. This does not look
         | burdensome.
        
       | neiesc wrote:
       | Awesome
        
       | croes wrote:
       | Is the ECG for a heart attack the same for women and men?
       | 
       | The symptoms aren't.
        
         | hwillis wrote:
         | The most common heart attack symptoms are the same for men and
         | women. The less common, less diagnostic symptoms are more
         | common in women. Over time the medical opinion has swung back
         | and forth (eg thinking women had less pain, until it was
         | recognized that many men have heart attacks without pain) but
         | the current consensus is that the important symptoms are pretty
         | much the same between men and women. Women may be more likely
         | to experience nausea during a heart attack, but you can't use
         | nausea to diagnose a heart attack and men get nauseated a
         | similar amount. These symptoms also don't take into account
         | body types, which have a big impact on the type of attack and
         | symptoms.
         | 
         | Men and women have slightly different ECGs and a doctor can
         | usually tell your gender from an ECG. The appearance of a heart
         | attack will be more similar than a normal heartbeat. Gender
         | differences have a much smaller impact on an ECG than things
         | like body mass and blood pressure. Overworked hearts will look
         | more like overworked hearts.
        
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