[HN Gopher] Vagus Nerve Stimulation Erases PTSD: Study
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       Vagus Nerve Stimulation Erases PTSD: Study
        
       Author : rmason
       Score  : 57 points
       Date   : 2025-05-07 19:38 UTC (3 hours ago)
        
 (HTM) web link (neurosciencenews.com)
 (TXT) w3m dump (neurosciencenews.com)
        
       | PaulHoule wrote:
       | Not surprising, it's been conjectured for a long time that
       | suppressing the physiological response would improve the
       | effectiveness of PTSD therapy
       | 
       | https://www.ncbi.nlm.nih.gov/books/NBK562942/
        
       | binarymax wrote:
       | My friend's startup is doing great stuff in this space to make a
       | VNS device for consumers. https://zenbud.health/
        
         | dark-star wrote:
         | Do these work the same as the professional/medical ones? A
         | friend of mine had one during a study, and she claimed it
         | worked by electrostimulation (small electric shocks), not
         | ultrasonic waves?
         | 
         | She wanted to buy one of those devices because they really
         | helped her but the cost was upwards of 1500EUR, this would
         | probably be within range for her, assuming it works the same
         | way?
        
           | metalman wrote:
           | text says "implanted device", which is going to put in by a
           | neuro surgeon
        
             | dark-star wrote:
             | I wasn't talking about the article, I was replying to a
             | comment about the zenbuds
        
         | m101010 wrote:
         | They promote their peer-reviewed clinical trial in the header
         | area. However, the spelling mistake 'Tial' should be fixed asap
         | :)
         | 
         | Maybe you can tell him that and also tell him that I am quite
         | interested in the device to check if it can reduce my heart
         | palpitations!
        
         | j45 wrote:
         | Neat, sensate is another device in this area.
         | 
         | Bio and neurofeedback devices are going to be an interesting
         | space the next 10 years.
        
         | ajb wrote:
         | I'm skeptical of these devices that say they are safe based on
         | CE or FCC testing. (zenbud says it has been CE tested). That's
         | consumer product testing, not health-device testing; I would
         | like to see some evidence that long-term use of a nerve
         | stimulation device causes no long term damage. I don't believe
         | that CE or FCC tests show that. It's disingenuous to have a
         | press release saying "Yay! We passed CE testing!" as if that
         | was like FDA approval.
        
           | deno wrote:
           | FWIW the EU also has EUDAMED registry for producers,
           | distributors and importers of medical devices and there are
           | additional regulations beyond CE under the MDR directive.
           | 
           | I don't see "ZenBud" or "NeurGear" in the EUDAMED database.
           | 
           | An ultrasonic device delivering energy to human tissue would
           | be a class 2a or 2b active medical device under MDR.
        
       | neves wrote:
       | Just 9 patients. :-(
        
         | nativeit wrote:
         | Isn't that fairly common for the first round of human testing
         | for novel treatments like this? I could certainly understand
         | wanting some small scale reassurance that a wider study won't
         | be throwing good money after bad.
        
           | msabalau wrote:
           | And, as in study notes, to prioritize understanding safety
           | with this population before worrying about efficacy.
        
         | inglor_cz wrote:
         | It is quite normal to start with small groups for economic
         | reasons. If the first results look promising, you can scale up.
         | If they are a wash, you haven't spent too much money on chasing
         | yet another placebo.
        
           | j45 wrote:
           | Also an opportunity to further design or evolve the study.
        
           | jrsdav wrote:
           | Not just economic (although it definitely ties into it) --
           | finding an eligible patient population also another
           | complicating dimension.
        
       | nativeit wrote:
       | Not surprised, but the headline is pretty terrible. This is a
       | very small, early stage experiment with promising results. The
       | declarative statement-of-fact in the headline is just
       | irresponsible clickbait. That said, the results are promising.
        
       | amelius wrote:
       | Why not use EMDR instead?
       | 
       | https://en.wikipedia.org/wiki/Eye_movement_desensitization_a...
        
         | j45 wrote:
         | Instead of either/or why not try both?
        
         | carabiner wrote:
         | None of these treatments has a 100% success rate. You can try
         | EMDR on Youtube and if it worked all the time, psychiatrists
         | would be out of a job.
        
           | apercu wrote:
           | Not all licensed therapists or psychiatrists provide EMDR. Or
           | did you mean psychiatrists specifically as they prescribe
           | ssri's?
        
           | airbreather wrote:
           | Yeah I said it was dhit when my ex-wife said she was going to
           | do it, but it definitely did something.
           | 
           | And I am well aware of the placebo effect.
           | 
           | But just because something is not provable or falsifiable
           | under current scientific knowledge, it does not mean it is
           | neccesarily quackery, there's a Venn diagram there where some
           | things may be effective.
           | 
           | Automatically discarding something that even occasionally
           | gets results, because it doesn't fit current "knowledge" is
           | the height of arrogance.
        
             | Sylamore wrote:
             | Sadly it made my ex-wife worse off than before - she went
             | from a functioning anxious person to being completely
             | overwhelmed by anxiety all the time.
        
               | airbreather wrote:
               | Unfortunate, the whole landscape on this is littered with
               | mines and finding truly knowledgeable help is difficult,
               | most seem to just push their favourite flavour,
               | regardless of the patient.
        
         | breppp wrote:
         | > improving outcomes for therapy-resistant PTSD patients.
        
         | msc1 wrote:
         | From wikipedia:
         | 
         | EMDR has been characterized as pseudoscience, because the
         | underlying theory and primary therapeutic mechanism are
         | unfalsifiable and non-scientific. EMDR's founder and other
         | practitioners have used untestable hypotheses to explain
         | studies which show no effect.[55] The results of the therapy
         | are non-specific, especially if directed eye movements are
         | irrelevant to the results. When these movements are removed,
         | what remains is a broadly therapeutic interaction and deceptive
         | marketing.[52][56] According to neurologist Steven Novella:
         | [T]he false specificity of these treatments is a massive
         | clinical distraction. Time and effort are wasted clinically in
         | studying, perfecting, and using these methods, rather than
         | focusing on the components of the interaction that actually
         | work.[57]
        
           | tartoran wrote:
           | Possibly has placebo effect. I know someone who did EMDR and
           | said it helped them a lot.
        
         | creatonez wrote:
         | It may work, but there's essentially no evidence in the medical
         | literature that it does.
        
         | haswell wrote:
         | Purely anecdotal, but EMDR was not helpful for me. I'd heard
         | many good things about it and had high hopes, but found it
         | somewhat counterproductive. I think this somewhat depends on
         | the nature of the trauma leading to the PTSD (e.g. a one time
         | major event vs. complex trauma over an extended period).
         | 
         | I was dealing with the latter.
        
       | 0xWTF wrote:
       | Link to the actual abstract on PubMed:
       | https://pubmed.ncbi.nlm.nih.gov/40097094/
        
       | matthew_morgan wrote:
       | Anyone done VNS at home?
        
       | ferd wrote:
       | Any hope to treat tinnitus? :-\
        
         | computerdork wrote:
         | There with you:( ... and actually, scheduled to get that
         | "Lenire" device in a couple of weeks. Hope works
        
         | codr7 wrote:
         | I realize some people had severe damage to their ears, but for
         | the rest I would recommend having a look at Nada Yoga.
        
       | pizza wrote:
       | I don't think there is clinical level evidence for it, but
       | there's this thing called Trauma Releasing Exercise which
       | apparently some people swear by. The idea is that you do
       | extremely taxing, high neuromuscular-recruitment static holds etc
       | - til the point of total muscle control loss that turns into
       | widespread trembling. I would speculate that if a big part of
       | feeling bad is getting stuck in a state where tension becomes a
       | problematic passive default state that is hard to get out of,
       | that a short, hard 'nudge' in the form of overwhelming exertion
       | might be enough to 'reset'. All speculation until proven though.
       | 
       | What's interesting about the origins of the technique is that the
       | guy thought of the possibility that adults learn to suppress
       | visible trauma reactions - uncontrolled shaking, etc - whereas
       | children and animals wouldn't, and for whatever reason they would
       | also be able to return to normal more quickly. He wondered if
       | maybe that there was a tangible benefit to the shaking itself, in
       | that it could help perturb out of the traumatized state itself.
        
         | computerdork wrote:
         | Wow, this makes a lot of sense. Nothing like a super intense
         | workout to relieve stress. I need a short one every night after
         | a long day. Feels like it erases all the crap I went through
         | during the day.
        
         | pseudocomposer wrote:
         | In the last few years I've definitely learned I get some sort
         | of "release" from practicing/holding handstands and other
         | hand/arm-balancing moves and, later, (less so, but with less
         | weird looks from people) from yoga balances (tree, warrior 3,
         | eagle, [revolved] half moon, dancer).
        
         | goda90 wrote:
         | > I don't think there is clinical level evidence for it
         | 
         | Even if it's 100% placebo, if it's not harmful, and it works
         | for a person, then it works. But, determining if it's not
         | harmful should be a priority. I found this person saying it
         | made their life worse, for example:
         | https://www.reddit.com/r/CPTSD_NSCommunity/comments/ungaew/t...
        
           | detourdog wrote:
           | I think you are correct. The strangest things I have learned
           | about personality disorder is that diagnosis applies for as
           | long as the disordered behavior exists.
           | 
           | If the disordered person's behavior adapts to "social norms"
           | the diagnosis no longer applies.
        
             | parineum wrote:
             | You're somewhat implying this but I'm not sure if you know
             | it exactly but others might find it informative...
             | 
             | The reason for that is that the "disorder" part of it is a
             | requirement that it get in the way of normal living. You
             | can have anxiety but if you take a deep breath and you can
             | overcome it, it's not a disorder. If that doesn't help or
             | even if you just haven't tried it, it's a disorder.
        
         | sthatipamala wrote:
         | The holds are not "extremely" taxing, I would say. The tremors
         | can be induced through a simple 7 step sequence of holds like
         | wall sits or calf raises. There are walkthroughs on YouTube.
         | 
         | On the TRE subreddit [0], people report being able to tremor at
         | will once they have enough experience with the technique.
         | 
         | Not trying to be pedantic, just clarifying that it is very
         | accessible! I've personally been experimenting with it and find
         | it to be helpful.
         | 
         | [0] https://www.reddit.com/r/longtermTRE/
        
       | ivape wrote:
       | I don't know how I feel about this. The nature of PTSD is that
       | you have a true memory, that the event happened. Imagine if I
       | tell you, 9/11 was real and it happened, but from now you will
       | never feel any feeling about it. What exactly did we accomplish
       | here? The bombings in Gaza are real, but from now on, you will
       | feel nothing about it. You see? It reads like a dystopia.
       | 
       | There's an obsession with erasing the past and not digesting it.
       | The subconscious wants reconciliation, and it will emerge over
       | and over, that's what PTSD is. Lobotomizing someone is certainly
       | _one way_ of reconciling it. The only way out is through imho,
       | that you are forever changed and saw the face of mankind, and
       | your subconscious will not accept any cheap reconciliation for
       | the most part.
       | 
       | "Just zap it", I sense the subconscious will not let you get away
       | with that. You are custodian of the trauma.
        
         | The_Amp_Walrus wrote:
         | you're conflating "not having an overwhelming negative reaction
         | to it" with "never feel anything about it"
         | 
         | you can know something is bad and act accordingly without
         | having a disordered and painful relationship with it
        
           | ivape wrote:
           | But you are _supposed_ to have a painful relationship with
           | it. You are never ever supposed to be at peace with it. It 's
           | who you become as the holder of that pain that provides any
           | foundation. In a sense, "zapping it" limits your potential. A
           | surrogate mother robs the mother of child-bearing (in all
           | normal cases like Kim Kardashian, not for cases where the
           | original mother cannot physically give birth). That's just a
           | fact. The trauma event has already robbed them, why rob them
           | twice?
           | 
           | Most people will have no capacity to feel what you feel about
           | it. You have the gift of feeling what is _necessary_ to feel
           | about that event. It 's precious, and it needs to be
           | nurtured. My utter contempt and sorrow for what I feel about
           | certain things belongs in the world, as best as I can hold
           | and steer it.
           | 
           | No one can feel your pain, and if you zap it, then not even
           | you can feel it. It's unloving to yourself and your
           | experience.
        
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       (page generated 2025-05-07 23:00 UTC)