[HN Gopher] New studies offer insight into Lyme disease's treatm...
       ___________________________________________________________________
        
       New studies offer insight into Lyme disease's treatment, lingering
       symptoms
        
       Author : gmays
       Score  : 148 points
       Date   : 2025-05-06 11:38 UTC (11 hours ago)
        
 (HTM) web link (news.northwestern.edu)
 (TXT) w3m dump (news.northwestern.edu)
        
       | AnthonBerg wrote:
       | The studies mentioned (but not linked?):
       | https://scholar.google.com/scholar?oi=bibs&hl=en&cluster=179...
       | 
       | https://scholar.google.com/scholar?oi=bibs&hl=en&cluster=384...
        
       | jadbox wrote:
       | This is desperately needed. I have Midwest family who have
       | suffered ten years due to persistent lyme disease from having a
       | single tick bite.
        
         | registeredcorn wrote:
         | Same. Family member who lived out around Utah and Colorado. She
         | had been racked with pain for something like 15-20 years. She
         | was going to doctors constantly, trying to figure out what was
         | wrong. She was labeled as a "drug seeker" and got shoved around
         | for years as a result.
         | 
         | Later on, she came across a doctor who happened to used to live
         | in the North East and recognized it as Lyme disease pretty much
         | instantly. She still deals with pain on a constant on-going
         | basis, but has been _slightly_ lessened with more targeted
         | medications, etc. Hopefully something like this can offer her
         | and others like her some sustainable, long-term relief.
        
       | adregan wrote:
       | Wasn't there a new Lyme's vaccine in the works due to come out
       | soon? Anyone aware of how that's going?
        
         | giantg2 wrote:
         | The one I heard about is supposed to be an antibody injection.
        
         | bluGill wrote:
         | In clinical trials - the one I was able to find has the first
         | report due end of 2026, with the final end of 2027. I assume 6
         | months or a year after that to do paperwork before approval so
         | I'm guessing late 2028 before we get it (assuming it passes
         | trial, which isn't a given)
        
         | colinwilyb wrote:
         | Clinical trials still ongoing.
         | 
         | https://www.pfizer.com/news/press-release/press-release-deta...
        
       | giantg2 wrote:
       | I thought that there are approved human vaccines, but they were
       | voluntarily removed due to economic reasons and lack of adoption.
        
         | bluGill wrote:
         | There was, withdrawn in 2002. Protection wanes so even if you
         | were one of the few who got it then you have no protection
         | today. There are a couple new vaccines in the works, one in
         | phase 3 testing so hopefully we get something in a few years.
        
           | mplanchard wrote:
           | Yeah there's what looks like a solid candidate going through
           | a variety of worldwide trials right now.[0]
           | 
           | Very hopeful for a meaningful means of prevention in the
           | coming years.
           | 
           | [0]: https://www.pfizer.com/news/press-release/press-release-
           | deta...
        
             | giantg2 wrote:
             | How is this really different from the previous Lymerix?
             | Aren't they both 3 shot series and OspA based?
        
           | giantg2 wrote:
           | It was withdrawn, but the approval was never revoked.
        
             | bluGill wrote:
             | True, and I suppose the patent is expired by now so you
             | could in theory start making it. Though the FDA has rules
             | about how you can produce such things. Probably better for
             | a company to risk/start a new vaccine which they can patent
             | and thus get some benefit that way vs one out of patent.
             | Also just because you can legally make it doesn't mean it
             | is practical. It may require other things that are not
             | longer made, or specific equipment that would be expensive
             | to recreate. Still this is an opportunity for someone in
             | India (where a lot of generic drugs are made already,
             | though the country doesn't matter) if they want to.
             | 
             | I don't hike as much in areas where Lyme is common as I
             | used to, but I'd still take a vaccine if I could. (I didn't
             | know the vaccine existed in 2001 or I would have)
        
         | ixtli wrote:
         | iirc the vaccines stopped the tick from successfully
         | transferring the bacteria. it didn't make the body able to
         | better combat it. (and if you read the article linked it
         | explains that its not actually the killing of the spirochete
         | that is the problem its the remains of it and how the host body
         | responds to those remains.)
        
         | ghaff wrote:
         | It's a complicated story. There were (almost certainly
         | overstated by some) side effects and it just wasn't a super-
         | effective vaccine. Still IMO shouldn't have been take off the
         | market. Hopefully one of the vaccines under development pan out
         | because Lyme is a real problem in some areas and increasingly
         | spreading north.
        
         | micromacrofoot wrote:
         | There are multiple human vaccines in the works at the moment,
         | earliest might be available towards the end of 2027 as long as
         | they're not defunded by the current administration
        
       | dev_l1x_be wrote:
       | It is kinda funny that humanity can kills entire species like the
       | dodo while cannot eradicate a bacterium like Borrelia.
        
         | quesera wrote:
         | Big things are easier to eradicate, especially if they are
         | slow, unaccustomed to being prey, and nutritious.
         | 
         | Eradicating a bacterium with wild animal reservoir populations
         | (deer, white-footed mice, black-legged ticks, all of which are
         | endemic species) is ... a _much_ harder problem.
        
         | monster_truck wrote:
         | If I could hunt Borrelia with spears it would be over
        
           | voidmain0001 wrote:
           | I would like to kill more deer which are part of the Lyme
           | cycle. There are so many in the rural area I live, they
           | remind of big city rats.
        
         | rarrrrrr wrote:
         | Strangely enough, there's even some likelihood that killing off
         | the passenger pigeon actually promoted Borrelia burgdorferi.
         | The passenger pigeon's main food source was tree mast. Large
         | flocks of pigeons would descend and clear the forest floor of
         | food. After it went extinct, the population of small animals
         | which also eat tree mast exploded, and these are reservoir
         | species for Borrelia.
        
           | BurningFrog wrote:
           | A Passenger Pigeon relaunch is planned for 2032:
           | 
           | https://reviverestore.org/projects/about-the-passenger-
           | pigeo...
        
         | nkrisc wrote:
         | There were far fewer dodos than any given bacteria. You can
         | also see a dodo.
        
         | bregma wrote:
         | Borellia bergdorfii does not taste like chicken.
        
       | CyberDildonics wrote:
       | Bypassing the clickbait we have this:
       | 
       |  _In two new studies led by bacteriologist Brandon L. Jutras,
       | Northwestern scientists have identified an antibiotic that cures
       | Lyme disease at a fraction of the dosage of the current "gold
       | standard" treatment and discovered what may cause a treated
       | infection to mimic chronic illness in patients. The studies were
       | published in the journal Science Translational Medicine._
        
       | bentt wrote:
       | This is amazing and really needed in the northern US and Canada.
       | It is also great they speak to the chronic lyme condition because
       | many people get accused of it being psychosomatic or even false
       | (similar with long Covid). Their theory of it being bacterial
       | remnants in the liver is validating.
        
         | ixtli wrote:
         | Its sad that we needed to have a partially avoidable mass death
         | due to COVID in order for people to start considering these
         | chronic conditions more broadly in society. People have been
         | having these issues for generations.
        
           | bentt wrote:
           | I mean, sure.
           | 
           | But some things are just really complex and the root causes
           | are very, very difficult to pin down. There was a lot sad
           | about COVID, but like 4000th on the list is how it revealed
           | the human dynamics that lead to chronic diseases being
           | overlooked because science has no valid explanation for
           | what's happening to patients. I say this as someone who
           | suffered from Lyme Disease for a number of years.
        
           | agos wrote:
           | look at it the other way: we got a couple of unexpected
           | silver linings from the COVID hell. one is attention to these
           | chronic conditions (finally!)
        
             | bentt wrote:
             | Yes! It's vital that we continue to look for opportunities
             | in the midst of such a crisis.
        
           | almosthere wrote:
           | Now everyone agrees, experts are just normal people that have
           | built a bias towards one ideological thing or another.
           | 
           | Long COVID? (looks up "party" stance)... that doesn't exist.
           | Eat Apples.
        
         | Aurornis wrote:
         | > It is also great they speak to the chronic lyme condition
         | because many people get accused of it being psychosomatic or
         | even false (similar with long Covid).
         | 
         | I have a friend who worked in research for rare, chronic, and
         | misunderstood diseases for a few years. Post Treatment Lyme
         | Disease Syndrome (PTLDS or just PTLD) is well accept by now.
         | 
         | The problem they encountered was that so many of the people who
         | presented with "Chronic Lyme" diagnoses were either self-
         | diagnosed from the internet or diagnosed by uninformed primary
         | care doctors who used it as a catch-all for symptoms they
         | couldn't diagnose. Many had never received positive test
         | results, or they had received positive test results from cash-
         | pay alternative medicine labs who used their own in-house
         | alternate tests.
         | 
         | It was really depressing to hear stories about people who had
         | been misled into spending tens or hundreds of thousands of
         | dollars on things like year-long courses of expensive, IV
         | antibiotics for a condition they most likely did not have. Even
         | the idea of a persistent infection hasn't held up to scrutiny.
         | The current line of thinking is shown in this article, where
         | persistent particles of past infection might cause ongoing
         | immune-related symptoms. Those symptoms would not respond to
         | the high-dose, long-term antibiotic therapy pushed by the
         | alternative medicine Lyme treatment providers, obviously.
         | 
         | So while it's a difficult topic, having some better mechanism
         | to separate the verified Lyme cases from the self-diagnosed or
         | those wrongly diagnosed is actually very important for
         | improving acceptance of the condition. It's tragic that many
         | with persistent symptoms of true Lyme infections have been
         | dismissed, but it's also tragic that many with non-Lyme
         | conditions have been misled into thinking that "Chronic Lyme"
         | is the explanation for all of their problems contrary to the
         | evidence. Getting the latter group out of the "Chronic Lyme"
         | mindset and on to a path where their true underlying condition
         | can be addressed, whatever it may be, is a win for them.
        
       | ChrisArchitect wrote:
       | Earlier release that links the study:
       | https://news.northwestern.edu/stories/2025/04/the-antibiotic...
       | (https://news.ycombinator.com/item?id=43863980)
        
       | netaustin wrote:
       | I contracted Lyme disease while on vacation in Cape Cod last
       | year. The first symptom was left-side facial paralysis, which my
       | physician diagnosed as Bell's Palsy, so I spent two weeks on
       | steroids before we figured out the real issue. Three weeks of
       | doxycycline cured the Lyme but left feeling pretty wrecked for
       | more than a month afterwards! I seem to have avoided the chronic
       | symptoms some people experience, but a low-dose antibiotic would
       | have been great.
        
         | hentrep wrote:
         | Disclaimer: Not a doctor.
         | 
         | I think you're alluding to this in your last statement, but
         | standard treatment for Lyme can absolutely wreck your natural
         | gut microbiome. This could explain some of the lingering
         | chronic effects post-treatment. Did you try supplementing with
         | fermented foods or probiotics after completing dox?
        
         | voidmain0001 wrote:
         | I'm on a second round of Doxy. The first was 21 days and now I
         | have a 60 day prescription. It doesn't knock me out. I take the
         | first dose early in the morning with a lot of water. I don't
         | eat until noon, but not before first taking a capsule of
         | probiotics to replenish gut bacteria. I take the second Doxy in
         | the evening with a meal. Then 3 hours later I take another
         | probiotic capsule to restore gut bacteria overnight. Maybe that
         | regime is helping or maybe I'm just fortunate.
        
           | ToDougie wrote:
           | Which probiotic?
        
         | dec0dedab0de wrote:
         | Just to be pedantic, Bell's Palsy is the name of the condition
         | not the cause. So it was Bell's Palsy caused by Lyme disease.
         | 
         | I have noticed that the line between condition and cause is
         | often overlooked, even by doctors. For example this leads to
         | people thinking Pinkeye/conjunctivitis is highly contagious,
         | when it is still conjunctivitis if it is caused by getting
         | something in your eye. I think that holds for everything that
         | ends in -itis too Sinusitis, Arthritis, Tendonitis, etc.
         | 
         | I know that is a bit of a tangent, but you reminded me of
         | someone who had bell's palsy telling me that it was actually
         | shingles. I explained that just because it was caused by
         | shingles doesn't mean it stops being Bell's Palsy, just like
         | how it is still a cough if it's from the flu or from smoking.
         | They ended up getting really angry at me about it, but I think
         | hn might appreciate the semantics a bit more.
        
           | engineer_22 wrote:
           | Do you have trouble reading other people's emotions?
        
             | dec0dedab0de wrote:
             | No, I could clearly tell they were angry. I just never
             | understood why some people get angry about minor
             | corrections.
        
             | perching_aix wrote:
             | Do you?
        
           | brady8 wrote:
           | Much of being a physician is pattern recognition - the vast
           | majority of Bell's Palsy is idiopathic (generally viral), and
           | thus that's how we usually treat it. If we tested everybody
           | for everything everytime the health system(s) would collapse.
           | 
           | It definitely helps as a patient to advocate, and add
           | anything that a physician like myself maybe wouldn't always
           | ask, like if you've been a tick-infested area and/or
           | discovered a tick attached to yourself recently.
        
         | mikepurvis wrote:
         | My kid contracted it from a tick bite while camping in Ontario;
         | it showed as joint pain in the legs that would come and go for
         | like a week at a time. Made it tough to explain to the doctors
         | as by the time we'd get there, he'd be fine again.
         | 
         | In the end it was four weeks of doxycycline-- that was several
         | months ago and it doesn't seem to have recurred, thankfully.
        
         | serial_dev wrote:
         | A couple of years ago I had about 10 tick bites and one of them
         | resulted in the signature bull's-eye rash. Thankfully, I was
         | aware of the ticks and I was checking for the bull's-eye rash
         | to appear and it got treated with doxycycline.
         | 
         | Many people face symptoms months after the bite or they might
         | not remember getting bitten by a tick so it's common that it is
         | misdiagnosed and they get all kinds of ineffective and / or
         | unnecessary meds, so I added it to my "list of illnesses to
         | check" in case I ever get unexplainable neurological issues,
         | fatigue and joint problems.
        
           | tasuki wrote:
           | > was checking for the bull's-eye rash to appear
           | 
           | Note that the absence of that wouldn't mean you didn't get
           | lyme disease.
           | 
           | Where I live, most of the ticks carry lyme disease, yet not
           | that many people get infected: if you pull it out quickly,
           | you greatly reduce the chance of getting infected. Of the
           | people I know, perhaps 20% had lyme disease (and knew about
           | it, I must add).
        
             | hattmall wrote:
             | 1 in 5 people had Lyme disease where you live? Where is
             | that??
        
         | y-c-o-m-b wrote:
         | Doxycycline is my favorite antibiotic and the most effective
         | against chronic sinusitis and chronic prostatitis for me. I
         | only take it maybe once a year, but it does wonders for a good
         | long time.
         | 
         | It also cured my nearly lifelong IBS-D about a decade ago. I
         | had a small re-occurrence of IBS-D last year after so many
         | years without it. I was able to convince the doc that it fixed
         | it for me in the past, so he prescribed me doxycycline again.
         | Boom! All fixed just like before.
         | 
         | I have no idea why that particular antibiotic does the trick,
         | but I've taken so many others from amoxicillin line, bactrim,
         | even cipro, flagyl (gross) etc. and only doxy is the silver
         | bullet for me it seems.
        
       | binary132 wrote:
       | And here I thought "long Lyme" had been proven fake.
        
         | gavin-1 wrote:
         | "long Lyme" isn't well defined, but you're probably thinking of
         | chronic lyme [1]. This article refers to PTLD.
         | 
         | The distinction matters. Chronic lyme is quackery that
         | encourages people to pursue aggressive long-term antibiotic
         | treatment for a non-existent persistent bacterial infection.
         | Often these are people who have never been infected with
         | Borrelia in the first place.
         | 
         | The article directly contradicts the persistent (undetectable)
         | bacterial infection "chronic lyme" theory.
         | 
         | [1] https://en.wikipedia.org/wiki/Chronic_Lyme_disease
        
           | voidmain0001 wrote:
           | Agreed. Long Lyme certainly exists. I appear to have it as do
           | numerous acquaintances. I wrote "appear to have it" because a
           | blood test for Borrelia returns negative. However, just two
           | weeks ago a doctor told me that Borrelia can evade a blood
           | test by infecting the nervous system. That was news to me so
           | I found this from NIH in the USA.
           | https://pmc.ncbi.nlm.nih.gov/articles/PMC8870494/ Borrelia
           | can cross over to the CNS. Lovely.
        
             | IncreasePosts wrote:
             | What symptoms? How can you say your symptoms are from long
             | Lyme, and not something else, or just getting old?
        
               | voidmain0001 wrote:
               | My symptoms are spot on with Acrodermatitis chronica
               | atrophicans.
               | 
               | https://en.wikipedia.org/wiki/Acrodermatitis_chronica_atr
               | oph... https://www.ncbi.nlm.nih.gov/books/NBK563289/
        
             | Aurornis wrote:
             | > I wrote "appear to have it" because a blood test for
             | Borrelia returns negative. However, just two weeks ago a
             | doctor told me that Borrelia can evade a blood test by
             | infecting the nervous system.
             | 
             | The theory of persistent infection hasn't really held up.
             | There were a few researchers who claimed to have some
             | evidence, but it hasn't really been replicated. It's
             | largely been dismissed from mainstream research.
             | 
             | Sadly, it's still a favored theory in many alternative
             | medicine communities. It's also a really contentious topic.
             | There's a long history, including Lyme researchers leaving
             | the field after receiving death threats following
             | publication of research that didn't agree with the
             | alternative medicine theories.
             | 
             | > That was news to me so I found this from NIH in the USA.
             | https://pmc.ncbi.nlm.nih.gov/articles/PMC8870494/ Borrelia
             | can cross over to the CNS. Lovely.
             | 
             | To be clear, that article is about CNS penetration of the
             | infection, not _persistence_ of the infection.
        
               | voidmain0001 wrote:
               | Is there a reason you refer to alternative medical
               | communities in response to my comment? Considering I made
               | no reference to using alternative medicine, what does it
               | have to do with my comment? Do you have an agenda? I know
               | that I don't have one and neither did my comment.
        
       | loeg wrote:
       | > Northwestern scientists identified that piperacillin, an
       | antibiotic in the same class as penicillin, effectively cured
       | mice of Lyme disease at 100-times less than the effective dose of
       | doxycycline.
       | 
       | Would be nice if it translates to humans.
       | 
       | > The authors argue that piperacillin, which has already been
       | FDA-approved as a safe treatment for pneumonia, could also be a
       | candidate for preemptive interventions for those potentially
       | exposed to Lyme (with a known deer tick bite).
        
       | dcchambers wrote:
       | This is fantastic news. I live in Wisconsin - a tick and Lyme
       | Disease hot spot. Ticks are one of the few bugs that really freak
       | me out due to Lyme Disease, especially for my kids who spend a
       | lot of time out playing in the grass.
       | 
       | Any news on the development of the fight against Lyme Disease is
       | great news.
       | 
       | One key thing I've learned is that ticks are very unlikely to
       | spread disease-causing bacteria within the first few hours of
       | biting. So just do regular checks whenever you've been outside in
       | tick-prone areas and get them off right away if found. If removed
       | promptly the chance of infection is basically zero.
        
       | charlangas wrote:
       | Both of my sisters (currently mid-30s) have had their lives on
       | pause for over 10 years due to chronic Lyme disease because
       | doctors in Mexico hadn't ever even heard of it. It took 4 years
       | of pain for the first of them to be diagnosed. Not sure when, if
       | ever, they'll be cured because when you don't treat Lyme disease
       | within a few months of infection, it digs in and is incredibly
       | difficult to kill.
        
         | Aurornis wrote:
         | > Not sure when, if ever, they'll be cured because when you
         | don't treat Lyme disease within a few months of infection, it
         | digs in and is incredibly difficult to kill
         | 
         | FYI, the idea that active infection continues to exist in
         | hiding within the body is a fringe theory.
         | 
         | The linked article talks about one of the current theories for
         | why some patients have persistent symptoms after the infection
         | is treated. The theory involves certain components of the past
         | infection lodging themselves in the liver where they persist
         | and can cause symptoms.
         | 
         | This is a difficult topic because some alternative Lyme
         | treatment providers will tell patients they have a persistent
         | infection and then subject them to years of high-dose
         | antibiotics with no scientific basis, which can create a
         | separate set of problems without addressing anything.
        
       | formerphotoj wrote:
       | For more info on Lyme and related difficult to identify diseases,
       | NYT columnist Ross Douhat wrote a book about his experience w/
       | Lyme and his ongoing adaptations. It's called...
       | 
       | The Deep Places: A Memoir of Illness and Discovery
        
       | 3D30497420 wrote:
       | On a related note, the Trump administration frozen more than $790
       | million in federal funding for NU because of "ongoing federal
       | antisemitism investigations":
       | https://dailynorthwestern.com/2025/05/05/lateststories/by-th...
        
         | boplicity wrote:
         | This is what the "fight" with "elite" universities is _really_
         | about: No longer funding research.
         | 
         | That's the most important aspect of this thing. Every other
         | aspect of this is a sideshow to the main event. And the main
         | event very much is the de-funding of scientific research.
         | 
         | No longer funding this research is a _huge_ change. And one
         | that will eventually have far-reaching consequences for
         | _everyone._
        
           | 3D30497420 wrote:
           | I think it is even broader than that. It is removing any
           | potential opposition. That opposition is independent
           | institutions, such as universities, but also the truth
           | itself. If there's no one to research things, then how will
           | you know if something is "true" or not? If there's no one to
           | communicate those findings, how will anyone find out? Etc.
        
             | ToDougie wrote:
             | Independent institutions is an oxymoron.
        
       | roody15 wrote:
       | My mother got a tick bite and felt off and the doctor told her
       | she had allergies and sinus infection due to high pollen. Luckily
       | my younger brother is a physician and told her to go back and ask
       | for a Lyme disease test. They said okay but said Lyme disease is
       | really rare and wasn't necessary. Long story short she was
       | positive but was caught early enough that 30 days Doxy was all
       | she needed.
       | 
       | That same year I was bitten and had a super itchy spot near my
       | private regions. It was crazy itch and made a bullseye rash. I
       | went to a clinic and they said they had never seen the bullseye
       | rash and it was textbook Lyme disease (or one other common tick
       | disease). Same was treated with Doxy and was fine. It's an
       | strange disease because if caught early super cheap antibiotics
       | work well... but if has spread through your body it can take
       | years to recover and be quite serious!
        
         | The5thElephant wrote:
         | Why have I heard so many stories of doctors not wanting to
         | diagnose something as Lyme disease?
        
           | soulofmischief wrote:
           | I literally used to get laughed out of the clinic, told I was
           | a healthy young male and just needed to exercise more. After
           | a decade of this, I was finally diagnosed with gout,
           | something doctors had just been lying about testing for. No
           | one could believe someone could have gout in their 20s (It's
           | been developing since my late teens and I've generally had
           | arthritis my entire life, since I was a child).
           | 
           | It took a _physician 's assistant_, who happened to see me
           | one day when _both_ of my doctors were on their third
           | extended vacation of the quarter, to hear my plight, take my
           | suggestion of gout seriously, and do the leg work, also
           | revealing to me that  "full test panels" don't include uric
           | acid by default and that my doctors had been lying to me
           | about their thoroughness.
           | 
           | The assistant was also massively more knowledgeable about the
           | disease, its history, the history of treatment, etc., and
           | disease in general, than either of the two doctors running
           | the clinic. Really opened my eyes.
        
             | The5thElephant wrote:
             | Funny enough I also got diagnosed with gout once in my 20s.
             | I have always had somewhat bad toes/bunions (probably
             | partially genetic, and partially wearing only tight soccer
             | shoes as a kid) and I went to a wedding wearing some new
             | leather shoes that I hadn't broken in yet. The next day I
             | woke up with a fever and horrific pain in the sides of my
             | toes. Went to doctor and they did some tests and were also
             | seemingly surprised at the results indicating gout. They
             | asked me to come back in a week to double check, and by
             | then my symptoms were gone and the tests no longer
             | indicated gout.
             | 
             | Our bodies are such strange mechanisms.
        
               | soulofmischief wrote:
               | > They asked me to come back in a week to double check,
               | and by then my symptoms were gone and the tests no longer
               | indicated gout.
               | 
               | Ha. Do you still have symptoms? If not, yea just a bad
               | initial diagnosis. If you do still have symptoms
               | sometimes though, it should be noted that gout is hard to
               | test for when you're actively experiencing aggravated
               | symptoms, as the uric acid crystals are lodged into your
               | tissue and not freely available in the blood stream /
               | urine. This exacerbated everything quite a lot, as when I
               | was much younger I definitely got uric acid tests done
               | when my symptoms were at their worst.
        
           | dessimus wrote:
           | Lyme Disease : PCPs :: Lupus : Dr. House?
        
           | BiteCode_dev wrote:
           | Doctors are trained to be arrogant, dismissive of unknown
           | unknowns, and with a terrible understanding of statistics.
           | 
           | Add to that:                   - They have a lot of patients
           | and not enough sleep.         - They need to pay back a huge
           | student loan.         - They hold terrible responsibilities
           | and risk being sued.         - They don't have much time for
           | themselves, let alone update their knowledge.         - Most
           | patients are overreacting idiots, so it's a winning strategy
           | to ignore what they tell you most of the time.         - They
           | are not trained nor selected for empathy or open-mindedness.
           | 
           | And you get so many medical errors.
           | 
           | Basically, you have to double-check everything they do, and
           | endure their cynical rebuttal when you make suggestions, ask
           | questions or try things they didn't request.
           | 
           | I had to face many such errors myself, two almost lethal.
           | 
           | When you can, shop for one that is both good and is open to
           | discussion. But even then, there is a limit. At some point,
           | your doctor WILL fail you, so you have to take
           | responsibility, usually when you're weak and at a low point
           | in your life.
           | 
           | And if you are wrong, people will tell you you should have
           | listened to your doctor, but if the doctor is wrong, well,
           | shit happens.
           | 
           | One of my practitioners is a friend of 15 years, I literally
           | lived with him, he is considered top in his specialty. I'm
           | surrounded by people working at the hospital.
           | 
           | He saved my life once.
           | 
           | Even that is not enough. I still have to double check stuff
           | every time.
        
       | jpadkins wrote:
       | Good time to remind people that right next to the town of Lyme CT
       | is Plum Island Animal Disease Center, who happened to be
       | researching tick based disease transmission when Lyme disease was
       | first discovered (named after the town that had the first case).
       | Crazy coincidence.
       | 
       | https://www.defenseone.com/threats/2019/07/did-us-invent-lym...
        
         | goda90 wrote:
         | Evidence of bacterium that causes Lyme disease was also found
         | in the 5000+ year old "Iceman" mummy found in the alps. People
         | have described the disease in the 1700s, 1800s and in the 1900s
         | prior to the outbreak in Lyme. Ticks preserved alongside their
         | animal hosts in 1800s biologic samples also are found to have
         | it. Genetic sequencing of different bacteria samples suggests a
         | much older evolutionary tree than a few decades existence.
        
       | boplicity wrote:
       | How strange that scientific research just like this has become
       | extremely political.
       | 
       | Case in point: The Trump administration has cut Northwestern off
       | from over a quarter billion dollars in funding because of "anti-
       | semitism." Note, that the vast majority of this money is for
       | research just like the one linked in this article.
       | 
       | Of course, people seem to be arguing about anti-semitism more
       | than cutting off funding for research. But make no mistake:
       | cutting off research funding is _exactly_ what is happening. And
       | that has practically _nothing_ to do with antisemitism.
        
       | whyenot wrote:
       | Lyme disease does exist on the west coast, including in the Bay
       | Area. A friend in Los Altos got Lyme disease from a tick in her
       | yard. This is the worst time of year for ticks in the Bay Area.
       | I've picked off over 100 ticks while doing field work in Henry
       | Coe State Park. The one advantage we have on the west coast is
       | that our ticks are larger and you usually notice when one starts
       | crawling on your skin and especially when one bites you.
        
         | ToDougie wrote:
         | A friend from Sacramento visited me in SoCal and brought his
         | dog along. We hung out for a few days, and eventually I found a
         | bullseye rash on my leg but no tick anywhere on my body. I went
         | to urgent care and they recommended I see an infectious disease
         | specialist, pronto -- and to start doxy that evening. My
         | bloodwork came back with too few markers for them to call it a
         | case of Lyme disease, but the specialist felt strongly that we
         | made the right decision to use the antibiotics.
         | 
         | Everyone always told me there is no Lyme disease in NorCal.
         | Reading your comment helped me feel vindicated.
        
       | heelix wrote:
       | Our kid got bit by a tick. Was lucky enough that it had the bulls
       | eye pattern and was able to look it up. She got a crazy high
       | temperature. Was crazy. A strong antibiotic cleared it up.
       | 
       | I really wish there still was a vaccine available (for humans). I
       | treat my pant legs and jacket sleeves with permethrin, which
       | slowly kills the ticks - but does so usually before they would
       | attempt to bite. One of the better camping tricks that I've
       | applied to everyday life.
        
       | chasil wrote:
       | "...doxycycline (and other generic antibiotics) wreak havoc on
       | the microbiome, killing beneficial bacteria in the gut and
       | causing troubling side effects..."
       | 
       | Doxycycline is used as prophylaxis for a wide variety of
       | pathogens; either the risk is tolerable with them, or the alarm
       | is needlessly elevated.
       | 
       | https://www.fitfortravel.nhs.uk/advice/malaria/doxycycline
        
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