[HN Gopher] Novel color via stimulation of individual photorecep...
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       Novel color via stimulation of individual photoreceptors at
       population scale
        
       Author : radeeyate
       Score  : 165 points
       Date   : 2025-04-20 02:03 UTC (20 hours ago)
        
 (HTM) web link (www.science.org)
 (TXT) w3m dump (www.science.org)
        
       | K0balt wrote:
       | What is meant by population scale in this context?
        
         | turnsout wrote:
         | It's jargon for "a lot of cones." 10^3 to be specific.
        
           | K0balt wrote:
           | Cool, thanks. I skimmed the article on how to introduce new
           | colors to entire populations, that seemed like a really
           | promising capability! lol.
        
       | throwanem wrote:
       | Very _Snow Crash,_ maybe. If I recall, the cyberdecks in that
       | story used lasers to draw on the user 's retinas, rather than an
       | HMD.
        
         | NitpickLawyer wrote:
         | Microsoft Research had a project like this at one point, with
         | "goggles" that used lasers on your retina instead of LCDs to
         | project images. No idea what happened to the project, as I
         | haven't heard anything recently.
        
         | corysama wrote:
         | I swear I remember reading in the 80s about the Air Force
         | having monochrome VR goggles consisting of a per-eye laser,
         | magnetic oil lens for per-pixel depth focus, two perpendicular
         | rotating mirrors for the raster scan and a curved glass lens to
         | reflect and focus the raster scan on to the retina.
        
           | fy20 wrote:
           | Imagine walking through a shopping mall and suddenly having a
           | Nike logo projected directly onto your retine, obscuring
           | everything you see.
        
             | Levitz wrote:
             | "Welp, time for terrorism I guess"
        
             | throwanem wrote:
             | Yeah, I mean I haven't been to Vegas myself, but I've had
             | pillow talk with some people who went.
             | 
             | (All illuminated signage could be said to draw on one's
             | retinas, after all. The major differences I see with this
             | method beyond improved gamut are first that it rasters, and
             | second that I think we have to worry what happens if it
             | _fails_ to raster...)
        
       | jonas21 wrote:
       | > _Five subjects were recruited for this experiment ... Subjects
       | 10001R, 10003L, and 20205R are coauthors on the paper and were
       | blinded to the test conditions but were aware of the purposes of
       | the study. The other two subjects were members of the
       | participating lab at the University of Washington but were naive
       | to the purposes of the study._
       | 
       | Is it normal for the authors to experiment on themselves and
       | their colleagues like this? Or did they not like the idea of
       | laser-stimulating the photoreceptors of random strangers?
        
         | pvg wrote:
         | That is the tradition.
         | 
         |  _I tooke a bodkin gh & put it betwixt my eye & the bone as
         | neare to the Backside of my eye as I could: & pressing my eye
         | with the end of it (soe as to make the curvature a, bcdef in my
         | eye) there appeared severall white darke & coloured circles_
         | 
         | https://www.newtonproject.ox.ac.uk/view/texts/normalized/NAT...
        
           | sebmellen wrote:
           | Wow, I never knew that Newton risked retinal detachment to
           | prove his theories.
        
             | gnabgib wrote:
             | Not a Neal Stephenson fan then? (The Baroque Cycle
             | https://en.wikipedia.org/wiki/The_Baroque_Cycle)
        
           | parpfish wrote:
           | Also google "Giles Brindley" for another great self-
           | experimentation tale
        
             | krispyfi wrote:
             | Also Albert Hofmann and Alexander Shulgin
        
         | parpfish wrote:
         | Self experimentation is pretty common in psychophysics
         | experiments. I think a big part of it is that the experiments
         | are long and boring, so the scientists themselves are the only
         | people likely to pay attention and perform the task accurately
         | the whole time.
        
         | etrautmann wrote:
         | Yes - many psychophysics experiments require a LOT of time and
         | careful attention that would be tricky to get from random
         | participants. It's often not at all an issue of safety or risk
         | and more just the length, tedium, and motivation.
        
       | robertclaus wrote:
       | There is a theory that specific shades of colors are difficult to
       | recognize or differentiate unless you name them. I wonder how
       | unique these 100% saturated colors would look without context
       | compared to other colors.
        
         | qingcharles wrote:
         | A great many languages don't differentiate between green and
         | blue. There is simply one word for both.
        
           | Muromec wrote:
           | A great deal of languages only have one blue color
        
         | carlosjobim wrote:
         | Learning to see is a skill that we have to train. If you ever
         | try to paint or draw a picture from a photographic reference,
         | you will realize that you've spent your whole life blind. Even
         | with the photo right in front of you, it can be extremely hard
         | to paint certain details, because the brain simply refuses to
         | accept the photographic reality when it has another idea of how
         | an object should look.
         | 
         | As for colour, language does not help very much with being able
         | to see and understand them. What helps more is playing with
         | photographic software and getting a feel for the relations
         | within a system like HSL, or RGB.
        
       | tianqi wrote:
       | This story makes me remember that I had heard a fun fact a long
       | time ago that many people have never actually seen the colour
       | "violet" which is a single wavelength of visible light. Because
       | there are very few things that reflect only this wavelength in
       | reality. The purple colour we see is formed from a mixture of red
       | and blue, whether it's something in nature, screen displaying or
       | printing. I was so intrigued that I bought a 405nm laser torch
       | and invited some friends to a home party to 'See the real
       | violet'. That single wavelength of purple really made a different
       | experience, and with good friends, we had a great day.
       | 
       | The olo experiment was very interesting, and it told me that
       | today we even have the technology to stimulate a single cone cell
       | one by one in time. I know that we can't accurately display the
       | olo on screen right now, which also prevents any of these
       | articles from actually containing a picture of the olo. I think
       | it's very close to #00FFEE, and I'm making it the colour of my
       | Hacker News's top bar.
        
         | tines wrote:
         | > Because there are very few things that reflect this
         | wavelength in reality.
         | 
         | You mean few things that reflect only this wavelength? Because
         | I would think anything white would reflect this wavelength just
         | like any other.
        
           | tianqi wrote:
           | Yes, I meant reflecting only this wavelength. Thanks.
        
         | subb wrote:
         | You did send a specific wavelength to your retina, but that
         | wasn't violet. Because violet is a construct by your brain.
         | 
         | Color is not a property of wavelength. There's nothing special
         | about photons wiggling in the 380 to 750nm range.
         | 
         | In general it's not necessary to be this pendatic, but given
         | the topic here, I think it's important to realize this. It
         | takes a while because we are so good at projecting our internal
         | experience outward.
         | 
         | Remember the blue / black dress?
        
           | tianqi wrote:
           | In my personal conception, violet is the kind of colour at
           | the lower edge of the rainbow, which is a single wavelength.
           | And purple is what the brain constructs. However, of course,
           | the names of the colours are themselves vague.
        
             | bdelmas wrote:
             | Hmm if you talk to a colorist violet and purple are 2
             | different colors one more on the red and the other more on
             | the blue. That's still the construct of 2 wavelength
             | colors. So a made up color of our brain that doesn't exist.
        
               | dleary wrote:
               | "Violet" is a spectral color, which means that it is a
               | color formed by a single wavelength of light. And it is a
               | member of the rainbow (the spectrum).
               | 
               | "Purple" is a mixture of red and blue.
        
           | eviks wrote:
           | > did send a specific wavelength to your retina, but that
           | wasn't violet.
           | 
           | It was, by definition
           | 
           | > Color is not a property of wavelength.
           | 
           | Sure, it's a label
           | 
           | > There's nothing special about photons wiggling in the 380
           | to 750nm range.
           | 
           | There is - they activate different receptors your brain
           | relies on, hence leading to a distinct (from other
           | wavelengths) sensation
        
             | subb wrote:
             | The waves aren't inherently special, your retina is.
             | 
             | What if we were sensitive to the 200 to 500nm range? What
             | would be blue, violet and red then?
             | 
             | Our eyes and brain are the one constructing what we
             | perceive as color. It doesn't exists outside of us.
             | 
             | Here's good article on the subject:
             | https://anthonywaichulis.com/regarding-perception-
             | photograph...
        
               | Smithalicious wrote:
               | >What if we were sensitive to the 200 to 500nm range?
               | 
               | https://www.youtube.com/watch?v=A-RfHC91Ewc
        
           | carlosjobim wrote:
           | Violet is a real wavelength, below blue on the spectrum.
           | Where it becomes invisible to the human eye, it starts
           | getting called ultraviolet.
           | 
           | Magenta and purples are constructs by the brain, as you
           | mention.
        
             | subb wrote:
             | No, they are all constructed, including blue.
             | 
             | If I shine some wavelength to your eyeball and you say "it
             | looks blue", but then I change the surrounding and now it
             | looks white, I don't think you would conclude that the
             | original wavelength is blue.
             | 
             | We have a many examples like this, which prescribe that
             | vision is not at all an accurate wavelength measurement
             | device.
        
         | scotty79 wrote:
         | How did you spread laser light over larger area?
         | 
         | The idea I'm having right now is reflecting it off of the rough
         | side of aluminum foil.
        
           | tianqi wrote:
           | I remember we just simply shone at a white wall.
        
         | perilunar wrote:
         | > The purple colour we see is formed from a mixture of red and
         | blue, whether it's something in nature, screen displaying or
         | printing.
         | 
         | Well if it's on an RGB screen, or printed with CMYK inks then
         | it's not 'real' violet, but there must be plenty of natural and
         | artificial pigments that are actually reflecting violet light
         | and not blue + red light. I imagine any pure compound would be
         | doing this. E.g cobalt phosphate (aka cobalt violet).
         | 
         | You could tell by illuminating a sample with different light
         | sources. See metameric failure:
         | 
         | https://en.wikipedia.org/wiki/Metamerism_(color)#Metameric_f...
        
         | erik wrote:
         | > many people have never actually seen the colour "violet"
         | which is a single wavelength of visible light
         | 
         | The violet seen in a rainbow (in nature, not a photo) is legit
         | single wavelength violet. Same with the rainbows created from
         | shining white light through a prism.
         | 
         | It's true that you don't really get to see it in isolation very
         | often though. Maybe some flowers, birds, or butterflies? Or
         | maybe the purple glow you get from UV lights?
        
           | phkahler wrote:
           | Why is violet in the rainbow not a very blue color? I would
           | think it only activates the blue cones. 405nm is a nifty
           | color.
        
             | jfengel wrote:
             | Because the cone isn't really a "blue" cone, and neither is
             | the "red" one. The curves overlap in complex ways. A pure
             | violet photon also slightly stimulates the long wavelength
             | cone.
             | 
             | That's why red+blue=purple feels a bit like violet. It
             | creates a similar double firing.
             | 
             | (And why red plus green gives an even more accurate yellow.
             | The long and medium cones have a lot of overlap.)
        
               | GrantMoyer wrote:
               | This is a common misconception, but the sensitivity of L
               | cones ("red" cones) increases monotonically until about
               | 570nm (monochromatic yellow), so violet light stimulates
               | L cones the least out of all visible wavelengths of
               | light. Magenta light, a mixture of red and blue
               | wavelengths, stimulates L cones far more than violet
               | light. See Wikipedia's LMS responsivity plot[1] or the
               | cone fundamental tables from the Color & Vision Research
               | Laboratory at [2].
               | 
               | I think the misconception comes from plots of XYZ color
               | matching functions[3]. The X color matching function
               | indeed has a local maximum in the short wavelengths, but
               | X doesn't represent L cone stimulation; it's a
               | mathematically derived curve used to define the XYZ color
               | space, which is a linear transform of LMS color space
               | selected for useful mathematical properties.
               | 
               | [1]: https://en.wikipedia.org/wiki/LMS_color_space#/media
               | /File:Co...
               | 
               | [2]: http://www.cvrl.org/
               | 
               | [3]: https://en.wikipedia.org/wiki/CIE_1931_color_space#/
               | media/Fi...
        
             | carlosjobim wrote:
             | It is technically the bluest color possible. What we
             | perceive as true blue is different, and the brain has the
             | weird imaginary magenta gradient between blue and red to
             | confuse.
        
               | _aavaa_ wrote:
               | Meganta isn't imaginary, it's just non-spectral.
        
               | carlosjobim wrote:
               | It's imagined only in our minds, it fits the definition
               | better than anything else.
        
               | _aavaa_ wrote:
               | First of all, all colors are imagined only in our minds.
               | 
               | Second, the term imaginary color already exists, and it
               | refers to a specific thing [0], and the colors on the
               | line of purple are not one of them. What you are
               | describing is a non-spectral color. They exist in day to
               | day life and in nature, they simply do not have an
               | associated wavelength.
               | 
               | [0] https://en.wikipedia.org/wiki/Impossible_color
        
               | carlosjobim wrote:
               | What exactly are you trying to prove? The gradient
               | between red and blue (magentas) are the only fully
               | saturated colors that we can perceive, which aren't part
               | of the electromagnetic spectrum. That's fantastic. Do you
               | want to waste your life arguing about nothing instead of
               | enjoying the miracles of nature?
        
             | GrantMoyer wrote:
             | Blue light looks different from violet light, because blue
             | light activates M cones ("green" cones) more than violet
             | light does.
        
         | Nesco wrote:
         | You can make the difference between a single wavelength color
         | and a composite color which looks the same, by looking at
         | objects nearby.
         | 
         | If they are of one of the composite colors, they should appear
         | in their natural hue
         | 
         | Else they will just appear darker
        
         | bitwize wrote:
         | Violet is a true wavelength, and does occur in nature.
         | 
         | Magenta, formed by mixing red and blue, does not exist in
         | nature. For that reason, "magic pink" (full-brightness magenta,
         | #ff00ff) is often used as a transparency color when the image
         | format does not support an alpha channel (e.g., sprite sheets,
         | Winamp skins).
        
           | jameshart wrote:
           | It's not true to say that mixtures of red and blue 'do not
           | exist in nature'. Fuchsia petals really are that color. All
           | you need is a substance that preferentially absorbs green
           | wavelengths but reflects reds and blues.
           | 
           | What 'does not exist in nature' is a single wavelength that
           | produces the equivalent stimulation of your L, M and S cone
           | cells as a mixture of red and blue light does.
           | 
           | But most of what we see in nature is not single wavelength
           | light - it's broad spectrum white light reflecting off things
           | with absorption spectra.
           | 
           | The reason stuff looks so weird under certain LED lights or
           | pure sodium light is that the source light isn't broad
           | spectrum - it's missing wavelengths already - so the way it
           | interacts with absorption spectra is unintuitive. Something
           | that looks blue under white light should still look blue
           | under blue light - but a blue LED might just be emitting blue
           | frequencies that the object absorbs, so it looks black
           | instead.
        
       | foota wrote:
       | My shitpost is that they're lucky they didn't trigger a buffer
       | overflow :-) but really, it doesn't seem completely out of
       | question to me that it's possible that some unintended and
       | serious consequence could occur from your brain receiving some
       | stimulus that it doesn't naturally receive. I guess maybe there's
       | no biological analog, but obviously bad things can happen in
       | circuits, computers, etc., when this happens.
        
         | ImHereToVote wrote:
         | We can do this test on an ANN.
        
         | braingravy wrote:
         | The brain is remarkably resilient to that type of issue...
         | Temporary buffer overflow (if you like) can be easily induced
         | and observed with chemicals that modify function at the
         | receptor level; Psychedelics being a classic example. (Worth
         | noting there are many such chemicals used in medicine and
         | research that induce overflow in function besides perception.)
         | 
         | What I find fascinating is the neurological resilience that can
         | be observed at cellular and behavioral levels to bounce back
         | after an event like that.
         | 
         | Non-chemical interventions, like adaption wearing special
         | glasses that flip vision(1), are quickly accounted for by a
         | healthy brain.
         | 
         | 1:https://www.npr.org/2012/12/14/167255705/a-view-from-the-
         | fli...
        
         | OscarCunningham wrote:
         | An easy way to percieve an oversaturated colour like this is to
         | stare at one colour for a long time, and then switch to its
         | complementary colour. The superposition of the colour and the
         | afterimage of the same colour produces a more intense effect.
        
         | Skgqie1 wrote:
         | Your comment reminded me of an old short story:
         | https://en.m.wikipedia.org/wiki/BLIT_(short_story)
        
       | foota wrote:
       | This is really fascinating to me. I'm amazed they're able to
       | image the cells of the eye with sufficient resolution and speed
       | to achieve this. From the paper, "and targeting 10^5 visible-
       | wavelength laser microdoses per second to each cone cell.".
       | 
       | If I understand correctly, they first use one type of
       | spectroscopy (AO-OCT) to image the eye and build a map
       | classifying the type of cells, and then use AO-SLO to find the
       | positions of cells in real time. I assume that AO-OCT can't image
       | at a sufficient rate for the second part (or they would just use
       | one type?) so they need to first build this classification map,
       | and then use it to match the position of cells to their type (e
       | g., by overlaying the positions of cells with the classifications
       | and making them line up).
        
       | ratatoskrt wrote:
       | The Guardian's article on this[1] includes a quote from an
       | eminent colour expert at City:
       | 
       | > The claim left one expert bemused. "It is not a new colour,"
       | said John Barbur, a vision scientist at City St George's,
       | University of London. "It's a more saturated green that can only
       | be produced in a subject with normal red-green chromatic
       | mechanism when the only input comes from M cones." The work, he
       | said, had "limited value".
       | 
       | [1]
       | https://www.theguardian.com/science/2025/apr/18/scientists-c...
        
         | codesnik wrote:
         | identifying and shining light only on specific type of cells on
         | retina through the iris is of limited value? I personally
         | didn't know we even have that kind of precision.
        
           | ratatoskrt wrote:
           | It's just a typical response. What he means (in an admittedly
           | unnecessary, snarky way) is that this is not going to
           | revolutionise perceptual colour science. It's not going to be
           | an out-of-this-world experience, nor will it change our
           | understanding of how humans perceive colour. I personally
           | think it's pretty cool, though.
        
       | shermantanktop wrote:
       | As a colorblind person, I look forward to you normies arguing
       | over whether a dress is green or "super green."
        
         | nkrisc wrote:
         | Let's just settle it with a spectrometer.
        
           | fouronnes3 wrote:
           | Spectromers don't measure the subjective perception of color.
        
             | nkrisc wrote:
             | Of course, but trying to agree on the precise subjective
             | perception of color is fruitless since no two people will
             | perceive all wavelengths of visible light exactly the same.
        
       | InsideOutSanta wrote:
       | There are a bunch of "weird" colors that we don't see naturally.
       | Wikipedia has a page on them:
       | https://en.wikipedia.org/wiki/Impossible_color
       | 
       | Some can be created at home without any special equipment. For
       | example, you can't mix red and green and create a "redgreen," but
       | if you cross your eyes and have one eye see red and the other see
       | green, you might see a new color you haven't seen before.
       | 
       | I also see weird colors in displays with a high frame rate that
       | cycle between colors quickly. And at one point, I had a laser
       | shot in my eye, which destroyed part of my vision. Initially, in
       | that spot, I saw a weird iridescent silver-greenish color I had
       | never seen before. Although that was pretty cool, I wouldn't
       | recommend repeating this involuntary experiment just to see that
       | color.
        
         | soulofmischief wrote:
         | Stygian blue is my favorite. What an insane color.
        
           | dataflow wrote:
           | I see it but it doesn't really feel like a new _color_? It
           | just looks like blue on top of black. Maybe a new intensity,
           | if I was being super generous, but not a new color.
        
             | bigyabai wrote:
             | I think it qualifies as a new color. If we can't
             | differentiate colors on saturation, hue or intensity then I
             | don't know how there are supposed to be multiple colors at
             | all. It seems like fair play by the scientists, if a bit
             | shrewd in defining "new".
        
               | dataflow wrote:
               | > If we can't differentiate colors on saturation, hue or
               | intensity
               | 
               | I don't think I follow. We can obviously distinguish all
               | of these and do it on a daily basis... what do you mean
               | we can't?
        
             | InsideOutSanta wrote:
             | To me, Stygian blue doesn't look like blue on top of black.
             | It looks like black that glows blue, which doesn't make
             | sense in the real world. I think it is fairly described as
             | a new color--I would be quite unsettled if I encountered it
             | in real life.
             | 
             | Of course, colors are a hallucination our brain produces,
             | so perhaps different brains deal differently with an
             | unusual experience like Stygian blue.
        
               | dataflow wrote:
               | > It looks like black that glows blue
               | 
               | I could maybe buy that as a description, but...
               | 
               | > I think it is fairly described as a new color--I would
               | be quite unsettled if I encountered it in real life.
               | 
               | I don't feel this follows. There are a lot of things that
               | would unsettle me if I saw them, like if someone gave off
               | a visible aura. Heck, I even found a "black flame" a bit
               | unsettling, and I saw a literal video of it on YouTube
               | (look it up if you don't know what I'm referring to). I'd
               | feel similarly if I saw a transparent human too. The
               | feeling you get - or the fact that you haven't seen
               | something visually similar before - doesn't really imply
               | it's a new _color_ , I think!
        
               | daveguy wrote:
               | I get more of a black in the middle and blue glow around
               | the edges. Also not sure it qualifies as a new color. To
               | me, it's more like an interesting illusion that combines
               | black and blue.
        
         | eddd-ddde wrote:
         | I tried really hard to see the "redgreen", but it just felt
         | like an occlusion bug when two 3d objects have the exact same z
         | layer and fight to render on top of the other.
        
       | exe34 wrote:
       | it should be called octarine, since it was brought forth by the
       | magic of science!
        
       | perihelions wrote:
       | There's another ongoing thread about this paper,
       | 
       | https://news.ycombinator.com/item?id=43736005 ( _" Scientists
       | claim to have found colour no one has seen before
       | (theguardian.com)"_ -- 27 comments)
        
       | mppm wrote:
       | Very cool!
       | 
       | It would be cooler still if this technique could be used for
       | future VR technology, creating full immersion by targeting all
       | photoreceptors individually. But unfortunately... the optics of
       | the eye does not actually allow individual cones to be fully
       | isolated, as the spot size would be below the diffraction limit.
       | They discuss this in Fig. 2 and the first section of the results.
       | 
       | Even with a wide-open pupil and perfect adaptive optics, there
       | would be 19% bleedover to nearby cells in high-density areas,
       | while what they achieve in practice is 67% bleedover in a lower-
       | density (off-center) area. This is enough to produce new effects
       | in color perception, but not enough to draw crisp color images on
       | the retina. :(
        
       | thenoblesunfish wrote:
       | I wonder if hallucinogens or other altered mental states can
       | produce this effect, by inducing these sorts of internal signals
       | that can't be created by input through the normal channels.
        
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