[HN Gopher] First baby born in UK to woman with transplanted womb
       ___________________________________________________________________
        
       First baby born in UK to woman with transplanted womb
        
       Author : gmays
       Score  : 291 points
       Date   : 2025-04-17 14:36 UTC (3 days ago)
        
 (HTM) web link (www.bbc.com)
 (TXT) w3m dump (www.bbc.com)
        
       | sebazzz wrote:
       | Pretty amazing. I suppose that the effects of immunosuppressants
       | on pregnancy and the unborn child are already well understood.
        
       | dleeftink wrote:
       | I stopped and looked at the natal photo for a while. It is a
       | feeling I have not had before. This new life, chanced not only by
       | lineage but multiple family members and a host of research and
       | medical staff.
       | 
       | The image shows very little technology, but to me, is the epitome
       | of how life and progress can unite.
        
         | mbonnet wrote:
         | I was deeply moved looking at it as well.
        
       | jeffbee wrote:
       | This is incredible technology. But I am crying in American at
       | "Each transplant costs around PS30,000, he says."
        
         | throwuxiytayq wrote:
         | Completely dwarfed by the total cost of raising a child. It's a
         | surprisingly expensive hobby.
        
           | tough wrote:
           | Yea but in america such a transplant probably costs 300k just
           | to go to the hospital ez
           | 
           | prob also raising a child way expensier if you factor uni and
           | such into it vs UK
        
             | trollbridge wrote:
             | I don't think anyone in America is actually paying a bill
             | for $300,000 for a transplant. It's either paid for by
             | insurance, or if someone doesn't have insurance, via
             | hospital charity or a state medical aid plan. The only
             | exception would be an absurdly rich person who doesn't have
             | insurance.
        
               | nonethewiser wrote:
               | Why would insurance cover a womb transplant?
        
               | breppp wrote:
               | Presumably if the need is due to illness
        
               | Retr0id wrote:
               | Insurance often covers IVF
        
               | WalterGR wrote:
               | Only in some states, under some circumstances, and not
               | necessarily completely.
        
               | Rebelgecko wrote:
               | Would insurance cover a transplant that isn't necessary
               | for survival?
        
               | pyuser583 wrote:
               | They cover cornea transplants, which are necessary for
               | sight.
               | 
               | But they tend not to cover fertility stuff.
        
               | trollbridge wrote:
               | Don't worry, our current President promises to be the
               | "fertilisation President" and is pushing to cover IVF and
               | other fertility treatments mandatory on isursnfr.
        
               | lawn wrote:
               | Don't forget the people who don't have insurance and are
               | too poor to pay for the treatment, those suckers.
        
               | trollbridge wrote:
               | If someone is low income and doesn't have insurance, they
               | should apply for state Medicaid or other assistance
               | programs. These programs exist and are very helpful.
        
               | AngryData wrote:
               | While yes they should, that is still going to be minimal
               | coverage that doesn't cover tons of stuff, especially
               | something like voluntary uterus transplant.
        
               | trollbridge wrote:
               | It varies by state, but in some Medicaid is some of the
               | best coverage you can get. (I have a personal mission to
               | dispel the myth that poor Americans can't access health
               | care, because often they can - and spreading the idea
               | they can't leads to adverse health outcomes.)
               | Specifically, patients aren't ever charged for anything.
               | 
               | Uterus transplants are still experimental. The only ones
               | I could find in the U.S. are in clinical trials and are
               | being paid for by the institution to people accepted into
               | the program, such as the one at John Hopkins.
               | 
               | There are not gynecologists (yet) charging $200,000 for
               | uterus transplants in America.
        
               | wat10000 wrote:
               | "American health care is incredibly expensive."
               | 
               | "That's ok, other people bear the enormous cost."
               | 
               | Not really a win, that.
        
               | thehappypm wrote:
               | That's not how it works! The bill of $300k gets
               | negotiated down to like $20k.
        
               | wat10000 wrote:
               | The negotiated rate is still super high. There are
               | procedures where it costs less to fly overseas and get it
               | done self-pay than the out-of-pocket cost with insurance
               | in the US.
        
         | chrisrodrigue wrote:
         | That seems extraordinarily affordable for a permanent, life-
         | altering operation that needs 30 medics and takes 17 hours.
         | 
         | For a comparison, check out what a 1-month supply of a biologic
         | drug costs: https://www.goodrx.com/stelara
        
           | clort wrote:
           | It will not be permanent, she can have two babies but they
           | will remove the womb afterwards
        
           | morcus wrote:
           | The think that was the point, it's unimaginable that
           | something like that could only cost 30k in the US.
        
           | scythe wrote:
           | I'll raise you for the cost of a single dose of Pluvicto:
           | 
           | https://www.drugs.com/price-guide/pluvicto
        
           | pyuser583 wrote:
           | Is this permanent? I thought transplanted uteruses were
           | usually removed after birth.
        
         | morkalork wrote:
         | Only a low multiple of IVF treatment, remarkable!
        
         | adrianmonk wrote:
         | It's part of a clinical trial, and the staff donated their
         | time, so I don't think that number tells you anything
         | meaningful about what it would normally cost.
        
       | amelius wrote:
       | This is great news, but I wonder how that ever got approved given
       | the safety implications for mother and child.
        
         | bluescrn wrote:
         | Wondering the same. Surrogacy would seem like a much safer
         | option. Just use the working womb without transplanting it. Why
         | put two people through major surgery, plus additional risks for
         | the baby?
        
           | lloeki wrote:
           | > Surrogacy would seem like a much safer option. Just use the
           | working womb without transplanting it.
           | 
           | In some jurisdictions the former could be illegal while the
           | latter would be legal.
        
       | romaaeterna wrote:
       | "Grace was born with a rare condition, Mayer-Rokitansky-Kuster-
       | Hauser (MRKH) syndrome, where the womb is missing or
       | underdeveloped, but with functioning ovaries"
       | 
       | A rare, congenital, condition.
        
       | lifeisstillgood wrote:
       | It's incredible and Inwish long life and happiness to the newborn
       | and her family
       | 
       | I would like to reflect on the timing of this - the UK Supreme
       | Court just ruled something about a woman is a "biological"
       | definition - and I am willing to put a lot of money on many
       | people on both sides of that contentious debate struggling with
       | the idea that "someone born without a womb is a woman" and "hey
       | we can transplant wombs now"
       | 
       | Thousands of scientists and medical practitioners have taken
       | thousands of baby steps to get to this point. We should fund
       | every single one of them - we never know where research will take
       | us.
        
         | basisword wrote:
         | The Supreme Court wasn't deciding anything other than the
         | intention of an existing law and the meaning of the words in
         | that law (which were unclear enough to require clarification).
         | BOTH sides of the debate claiming that the Supreme Court has
         | now defined what constitutes a "woman" are wrong and doing
         | nothing but polarising people for their own selfish gain.
        
           | EA-3167 wrote:
           | Unfortunately when you try to explain this to people, the
           | most common response (regardless of which side they're on) is
           | to express that "Yes, but OUR side is right, so
           | misrepresenting the ruling in our favor is right too."
        
             | ChocolateGod wrote:
             | The same kind of people where if you're not on their
             | extreme, you're on the opposite extreme and might as well
             | be Satan himself.
             | 
             | You're not allowed to be in the middle anymore.
        
               | XorNot wrote:
               | People are rightly judged for saying they're "in the
               | middle" because too often their "middle" is just whatever
               | they perceptually decided the position of the left and
               | right was and then they picked their position in reaction
               | to that, rather then out of any consideration of the
               | issue.
               | 
               | People _love_ to be  "in the middle" and thus
               | "reasonable".
        
               | vacuity wrote:
               | You're both right. We don't distinguish between the
               | reasonable middle grounders and the unreasonable ones.
               | More broadly, we don't distinguish between reasonable and
               | unreasonable arguments. We never have. Truth as
               | determined by humans is basically a popularity contest.
        
               | EA-3167 wrote:
               | This is why the entire exercise of finding a place on a
               | political spectrum is a trap and a scam, the only thing
               | that really matters:
               | 
               | Are you an extremist or a moderate? Because I can get
               | along with a moderate person on the left, right, or
               | anywhere in between. By the same token extremists
               | regardless of stripe are unbearable.
        
           | qingcharles wrote:
           | This ^. It was your standard run-of-the-mill statutory
           | interpretation case. Limited to a single badly defined
           | statute, written somewhat carelessly. This is common for
           | statutes.
           | 
           | What often happens is that a "supreme" court like this will
           | file an opinion attempting to clarify the meaning as best
           | they can, but it really requires a statutory amendment by the
           | legislators to fix it. Often that is what happens next.
        
         | clort wrote:
         | As I understand it, the court ruled that specifically within
         | the text of the 2010 Equality Act, where it says 'woman' with
         | no qualifier, that refers only to biological females. I do not
         | know how many such places there are, but other parts of the act
         | do apparently refer to other women and that they should not be
         | discriminated against in the same way.
         | 
         | The court is really saying that the lawmakers did not specify
         | properly what they meant in certain cases and that they should
         | probably modify those sections (they are carefully not to tell
         | Parliament what to do), which can be done and does sometimes
         | get done when such things crop up.
        
           | ChocolateGod wrote:
           | > but other parts of the act do apparently refer to other
           | women and that they should not be discriminated against in
           | the same way
           | 
           | Yes, the act (as it should) protects people from
           | discrimination based on gender reassignment, e.g. you can't
           | fire someone for their gender identity or deny them from a
           | service.
           | 
           | The act makes it illegal to discriminate against someone due
           | to their "sex", but a portion of the act allowed for "single
           | sex" spaces where there is reasonable grounds to have them,
           | but the act (reasonably at the time) did not define what sex
           | was.
           | 
           | A piece of Scottish legislation referred to "woman as defined
           | by the Equality Act", but the Equality Act never said if it
           | was referring to biological sex or gender identity, the
           | Scottish government said it would include people with gender
           | reassignment certificates, a "woman's rights" charity
           | disagreed. Hence the court got involved and found the
           | original intention was to refer to biological sex, which was
           | confirmed by the politician that introduced the Equality Act
           | (Harriet Harman).
        
             | blippitybleep wrote:
             | _On the important issue of discrimination, Clause 9 makes
             | it clear that a transsexual person would have protection
             | under the Sex Discrimination Act as a person of the
             | acquired sex or gender. Once recognition has been granted,
             | they will be able to claim the rights appropriate to that
             | gender._
             | 
             | - Lord Filkin, the Minister who introduced the Gender
             | Recognition Bill in the House of Lords in 2003 (18th
             | December)
        
         | jl6 wrote:
         | It's not that confusing. "Has a womb" is not a common
         | definition of "woman". Women don't stop being women after
         | having a hysterectomy.
         | 
         | The woman in question is a woman because her sexual
         | differentiation followed the female pathway. Just because in
         | her case that pathway led to a DSD variant doesn't undo the
         | rest of her female development or make her a little bit less of
         | a woman, or male, or a third sex.
        
           | ben_w wrote:
           | There's at least four common definitions of "woman", and I
           | have in fact seen people use "has a womb" as one of them
           | despite, as you may guess, all the people piling on
           | immediately with a reply along the lines of what you yourself
           | say -- that this would exclude women who have had a
           | hysterectomy.
           | 
           | The other three I've commonly seen are:
           | 
           | (1) as you suggest, developmental pathway -- which tends to
           | trip people up over androgen insensitivity, and is also why
           | puberty blockers are part of the public debate
           | 
           | (2) chromosomes -- which has the problem of 0.6-1.0% of the
           | population doing something else besides the normal XX/XY
           | 
           | and (3) current external physical appearance -- which tends
           | to lead to confusion by both transvestites in public, and
           | also in private by anyone who has had top surgery but not
           | bottom surgery.
        
             | aisenik wrote:
             | Why do you use the the Nazi demographic term
             | "transvestite?"
             | 
             | (also, you should just not talk about trans people as you
             | display immense ignorance in a very short time, you clearly
             | have a concept of trans bodies that is rooted in fascist
             | propaganda: trans women on HRT develop breasts without
             | surgery).
        
               | ben_w wrote:
               | The word "transvestite" predates the Nazis by a few
               | decades, coined by someone the Nazis hated because he was
               | gay and Jewish:
               | https://en.wikipedia.org/wiki/Magnus_Hirschfeld
               | 
               | > trans women on HRT develop breasts without surgery).
               | 
               | Transgender people go both directions, not only AMAB but
               | also AFAB.
        
               | aisenik wrote:
               | I did intend to type "Nazi era", though I find the
               | clarification is meaningless to the point. I'm all for
               | reclaiming words, but I am unaware of any significant
               | efforts to reclaim and promote the word in question. It
               | is anachronistic and inextricably connected to 20th
               | century transphobia and violence against trans women in
               | particular
               | 
               | Re: your second point, a closer reading of the comments
               | will show that this thread is discussing "women."
               | 
               | e: The far more interesting discussion is whether the
               | revival of eugenics-era language is justifiable. This is
               | hardly the first example on this site of arrogant
               | commentators casually reviving language that came to be
               | understood as hateful in the 20th century.
        
               | ben_w wrote:
               | > I am unaware of any significant efforts to reclaim and
               | promote the word in question. It is anachronistic and
               | inextricably connected to 20th century transphobia and
               | violence against trans women in particular
               | 
               | It's the primary term I grew up with in the UK
               | specifically about what is also called cross-dressing.
               | 
               | It's also used by one of my favourite comedians, Suzy
               | Eddie Izzard, as self-description ("executive
               | transvestite") before she identified as transgender: http
               | s://en.wikipedia.org/wiki/Dress_to_Kill_(Eddie_Izzard)
               | 
               | > Re: your second point, a closer reading of the comments
               | will show that this thread is discussing "women."
               | 
               | 1) Quite a lot of transphobes focus entirely on women,
               | thus ignoring how their own rules end up forcing trans
               | men to end up in women's-only spaces.
               | 
               | 2) I am informed that many trans women have implants
               | before hormones. In fact, one woman I know openly
               | discussed face surgery as part of her transition.
               | 
               | Also: cis women have breast surgery. I'm told most often
               | as a reduction. Facebook, in its complete uselessness,
               | has advertised the surgery to me along with dick pills.
        
               | arrowsmith wrote:
               | I promise I'm asking this question in good faith because
               | I would genuinely love to understand your reasoning: why
               | does the term "transvestite" have anything to do with
               | Nazism?
               | 
               | From what I remember, that word was common and acceptable
               | when I was growing up in the 90s, and I don't remember
               | any Nazis using it. Nor did anyone tell me that the word
               | "transvestite" was derogatory or offensive, although if
               | social mores have shifted then fine, I won't say it.
               | 
               | What did I miss?
        
               | gcr wrote:
               | no worries, people typically use "transgender" or "trans"
               | as an umbrella term these days
               | 
               | I have heard of folks who claim the label "transveatite"
               | for themselves. Others see it as derogatory.
        
               | ben_w wrote:
               | I suspect there may have been a misunderstanding of my
               | earlier comment that led to this chain.
               | 
               | Where I wrote above:
               | 
               | > current external physical appearance -- which tends to
               | lead to confusion by both transvestites in public
               | 
               | That wasn't a statement about being transgender. I was
               | saying that people judge clothing, and are confused by
               | that clothing. "Public" being about clothing, because
               | there aren't many public places where you're going to see
               | enough skin for anything else to cause confusion.
               | 
               | ("vest" as in vestments, clothing).
        
           | crooked-v wrote:
           | US Republicans have literally passed laws defining "woman"
           | based on having a functioning womb
           | (https://kansasreflector.com/2023/07/05/what-is-a-woman-
           | heres...).
        
             | ChocolateGod wrote:
             | > US Republicans have literally passed laws defining
             | "woman" based on having a functioning womb
             | 
             | The bill referenced makes no direct mention of womb, nor
             | functioning. You're using "literally" a bit unfaithfully
             | there.
             | 
             | from the law
             | 
             | > a "female" is an individual whose biological reproductive
             | system is developed to produce ova,
        
               | gcr wrote:
               | isn't having a functioning uterus a hard prerequisite to
               | the ability to produce ova?
               | 
               | "is developed to produce ova" is a statement about
               | current capability. If they meant to include women with
               | hysterectomies, they would have worded it differently,
               | like "is or once was developed to produce ova;" if they
               | meant to include women with non-functioning wombs, they
               | would have written more broadly, like "is of the type
               | that usually produces ova" or something.
        
               | rkomorn wrote:
               | The uterus itself doesn't have much to do with ova
               | production.
               | 
               | Are you including ovary removal in your definition of
               | hysterectomy?
               | 
               | Or are you defining "ova production" as including
               | fertilization/implantation?
        
               | belorn wrote:
               | The answer is a yes, as in, the ovaries can still ovulate
               | even without a uterus. The ovaries also continue to
               | produce hormones, through there are a feedback loop
               | between the uterus and ovaries which get disrupted
               | without a uterus.
               | 
               | It is somewhat similar to how men with vasectomy still
               | produce sperm.
        
           | tomlockwood wrote:
           | What tests with what results would conclusively show which
           | individuals went down which pathway?
        
             | googlryas wrote:
             | Why do you suppose such a test could even exist?
        
             | jl6 wrote:
             | Depends why you need to know and with what level of
             | accuracy. Just looking at their face is about 96%-98%
             | accurate[0], and becomes even more accurate when other cues
             | are available such as voice, gait, and build. For casual
             | purposes, humans are incredibly good at predicting sex,
             | without any technology or scientific understanding. One
             | might speculate that being able to accurately find a mate
             | is an evolutionary advantage.
             | 
             | For the last few fractions of a percent accuracy, a SRY
             | cheek swab test is a simple non-invasive screening test
             | that can flag individuals for further investigation. World
             | Athletics have just implemented this test, stating it is "a
             | highly accurate proxy for biological sex".[1] A positive
             | result in this screening test could be combined with a
             | finger prick test for testosterone level to provide further
             | information, and at this point we're into methods of
             | medical diagnosis of DSDs. About 1 in 5000 individuals will
             | have a DSD, some of which are still unambiguously male or
             | female (e.g. XXY Klinefelter syndrome), and some of which
             | are almost unique individuals that defy categorization.
             | 
             | At this point, it is popular to seize on those rare
             | individuals and declare "aha! So sex isn't binary then! So
             | it must be a spectrum!", and while this is surely well-
             | intentioned, it is scientifically illiterate.[2] I suspect
             | part of the confusion is interpreting "binary" as a
             | mathematical Boolean value (where exceptions cannot, by
             | definition, exist) rather than as a scientific
             | classification, where exceptions can and do exist and
             | "prove the rule".
             | 
             | [0] https://www.sciencedirect.com/science/article/pii/S0042
             | 69892...
             | 
             | [1] https://www.bbc.com/sport/athletics/articles/cj91dr17d1
             | no.am...
             | 
             | [2] https://richarddawkins.com/articles/article/race-is-a-
             | spectr...
        
               | tomlockwood wrote:
               | So the SRY cheek swab test that the IOC ruled ineffective
               | before the 2000 Olympics is what you think is accurate?
               | Interesting.
        
               | jl6 wrote:
               | It is a _screening_ test, not a _diagnostic_ test. False
               | positives are possible, but so are followup tests for
               | those cases.
        
               | tomlockwood wrote:
               | I guess it doesn't answer my question then.
        
               | bryan_w wrote:
               | The question was:
               | 
               | >What tests with what results would conclusively show
               | which individuals went down which pathway?
               | 
               | You've managed to provide 0 tests that conclusively
               | answer the question.
        
           | gcr wrote:
           | A friend of mine takes estrogen and has breasts, feminine
           | voice, etc. Her body's arguably taken both sexual
           | differentiation pathways over the years. I think even this
           | definition isn't so clear-cut.
        
             | jl6 wrote:
             | Body modification through technology doesn't really
             | encroach on the scientific classification of the natural
             | world. The Vacanti mouse which had an apparent human ear
             | grown on its back was an amazing thing in its own right,
             | but its existence doesn't mean we need to update our
             | understanding of what a mouse is.
        
         | aaaja wrote:
         | > _I would like to reflect on the timing of this - the UK
         | Supreme Court just ruled something about a woman is a
         | "biological" definition - and I am willing to put a lot of
         | money on many people on both sides of that contentious debate
         | struggling with the idea that "someone born without a womb is a
         | woman" and "hey we can transplant wombs now"_
         | 
         | MRKH syndrome is a disorder of female sex development, and if
         | you look at this from the perspective of developmental biology
         | it's clear that anyone affected by this must be a woman. I feel
         | it shouldn't be too hard an idea to struggle with.
         | 
         | That they have a working womb transplant technique is
         | impressive from a medical technology point of view but I think
         | not enough has been said about the ethics of this
         | experimentation.
         | 
         | Personally I wouldn't risk exposing my baby to transplant anti-
         | rejection drugs. We don't know how this may impact the short-
         | term or long-term health of the baby.
        
           | XorNot wrote:
           | The same could've been said about IVF - the technology is
           | _not_ old, the first person born to it was only in 1978.
        
         | remarkEon wrote:
         | This is not actually a struggle whatsoever, it only is if you
         | pretend it is thus. Humans have 2 legs and 2 arms. It I was
         | born without legs, am I still a human?
        
           | contravariant wrote:
           | That's a gross oversimplification. Virilisation is a complex
           | process with many factors.
           | 
           | If you're still human if you're born without legs then
           | clearly neither genetic or developmental traits determine
           | someone's humanity.
           | 
           | So at what point do we call someone a woman born without a
           | uterus? When a 'normal' pregnancy would have resulted in them
           | having a uterus? When _different genetics_ would have
           | resulted in them having a uterus? Or when she herself
           | complains that she lacks a uterus?
        
             | remarkEon wrote:
             | I'm applying the same logic, I'm not simplifying anything.
             | You are using the word "humanity" to mean something
             | different from what the rest of the thread is talking
             | about. To address what I think your point is, many wish to
             | expand the malleability of basic biological concepts based
             | on edge cases. Edge cases for which we already have
             | definitions and categories. You are doing so now, by
             | attempting to entrench ambiguity on the entire concept of
             | "woman" by observing that the woman in TFA was born with a
             | specific, heritable, abnormality that prevented the nominal
             | development of a uterus.
        
           | ben_w wrote:
           | I was born as a baby, but I sure 'aint one now.
           | 
           | Here's another one for you, given how many people care about
           | XX/XY as a distinction of gender: Humans have 46 chromosomes,
           | but by this definition, about 0.6-1.0% of live births from
           | human mothers are of individuals who aren't human.
           | 
           | Language is a tool we use to create categories, don't let
           | language use you. Insisting that everything in reality must
           | conform to the categories that language already has, is
           | mistaking the map for the territory.
        
             | remarkEon wrote:
             | Language is more than a tool, though. It's how we
             | understand reality. My native language is English, I speak
             | a little Spanish, more than a little German, and used to
             | speak some other stuff (the use it or lose it kind). And in
             | every effort to learn those language you, well, learn
             | things about how to structure your thought and
             | understanding of things. I think you're mistaking my point
             | for something else.
        
               | ben_w wrote:
               | In learning German as an adult, one thing I keep noticing
               | is how a single word in one language is several in the
               | other.
               | 
               | English: Times, German: Mal or Zeiten.
               | 
               | "Every time" is "jedes Mal", but "good times" is "gute
               | Zeiten". "Three times four" uses "mal".
               | 
               | And every time a new thing gets invented, found, or
               | imported, neologisms pop up, or words get borrowed from
               | other cultures. In English, robins are said to have "red
               | breasts", because the colour orange had not yet been
               | coined when the bird needed a name, because the fruit
               | after which the colour is named had not yet arrived.
               | 
               | People also argue about if "vegetarian hamburgers" is a
               | sensible term, as if the "ham" implies meat, even though
               | (1) the meat varieties usually use beef, and (2) it's
               | named after the place Hamburg.
               | 
               | Before the development of hormonal and surgical
               | solutions, the only thing trans people could do was
               | change their clothes. At some point, the medical options
               | are so capable that any given previous definition of
               | gender becomes malleable. A womb implant is one such
               | option.
        
               | remarkEon wrote:
               | Sure, but Mal and Zeit intentionally elicit different
               | contextual meanings. The literal word is the same in
               | English but it's quite obvious that the context is
               | different, and in German the context calls for a
               | different word. English, while being within the Germanic
               | language family, isn't as particular in many ways as
               | German can be or is. If you can speak multiple languages
               | surely you understand what I am getting at. Vegetarian
               | "hamburgers" is a poor example because, well, the point
               | of calling something a "vegetarian hamburger" is that it
               | resembles a _real_ hamburger, which would contain meat.
               | Thus, you now understand my point about changing language
               | in this regard.
        
               | ben_w wrote:
               | > Thus, you now understand my point about changing
               | language in this regard.
               | 
               | I really don't.
               | 
               | As I say in such discussions, "you're only allowed to
               | call them 'hamburgers' if they're from the Hamburg
               | region, otherwise it's just a sparkling fried patty".
               | 
               | See also: https://xkcd.com/3075/
        
           | BriggyDwiggs42 wrote:
           | If you're writing laws, your choice of language matters quite
           | a lot. "Humans have 2 legs and 2 arms" alongside "humans are
           | entitled to unalienable rights" could lead to foreseeable
           | problems, so specifying in your writing that "humans
           | typically have two legs and two arms" would be a smarter bet.
           | It's not important in a hacker news comment, but is important
           | in law.
        
         | dyauspitr wrote:
         | This is just fudging to justify some trans based delusion. It's
         | all pretty straightforward.
        
         | noosphr wrote:
         | The biotech coming down the line will make our current culture
         | wars seem like a disagreement between two best friends.
         | 
         | All of the following are nearly possible today:
         | 
         | + A man implanted with a womb giving birth.
         | 
         | + A woman stealing genetic material and creating a baby, the
         | gender of the second parent is irrelevant here.
         | 
         | + A woman wanting an abortion, instead having the fetus removed
         | and placed in an artificial womb under the care of the father.
         | 
         | And one that I was working on:
         | 
         | + Farm animals grown with their brains shut off, used as
         | compute substrate for biological neural networks, while their
         | biological functions are controlled remotely.
        
           | lukemercado wrote:
           | > Farm animals grown with their brains shut off, used as
           | compute substrate for biological neural networks, while their
           | biological functions are controlled remotely.
           | 
           | I'm sorry, you were working on what? Where does one learn
           | more about this concept?
        
             | noosphr wrote:
             | >Where does one learn more about this concept?
             | 
             | One does not.
             | 
             | One builds the tools to run the experiments to discover the
             | rules.
             | 
             | The closest are FinalSpark and CorticalLabs, but they both
             | are only using in vitro neurons as the computational
             | substrate.
             | 
             | Neuralink et al. are working in vivo, but they are only
             | doing output and don't have any plans to do input, let
             | alone to actively disrupt normal neural activity and take
             | control of bodily processes.
             | 
             | If you're very interested feel free to drop me a line.
        
         | pyuser583 wrote:
         | I don't think anyone struggles with "someone born without a
         | womb is a woman."
         | 
         | When a woman is born without a womb, the doctors should
         | investigate and figure out why that is. Is something else
         | missing? Could there be other issues? A diagnosis should be
         | made.
         | 
         | No such investigation is necessary when a man is born without a
         | womb.
        
           | astura wrote:
           | You can't tell if a newborn girl has a womb or not. Not
           | without ultrasounds or scans.
        
       | Teever wrote:
       | This is really cool but it's ultimately a stop-gap measure.
       | 
       | Where we want to end up is with artificial wombs because that
       | will ultimately give individuals much more control over their
       | reproduction and will do away with the onerous physiological and
       | psychological stresses that pregnancy puts on women.
        
         | foolfoolz wrote:
         | brave new world
        
           | TrnsltLife wrote:
           | My baby banting Soon you'll need decanting
        
         | sitkack wrote:
         | I could see this being combined with pigs, to place human
         | embryos in pigs to carry humans to term.
         | 
         | An extra-uterine system to physiologically support the extreme
         | premature lamb https://news.ycombinator.com/item?id=14194422
        
         | TheBlight wrote:
         | Perhaps there's benefit to pregnancy for both the mother and
         | baby and fully detaching them from the experience might have
         | negative consequences.
        
       | Boogie_Man wrote:
       | Note this is currently not possible without the use of In vitro
       | fertilization
        
       | gbin wrote:
       | So if they do a DNA test, her sister is the actual biological
       | mother I guess.
        
         | astura wrote:
         | No, That's not how any of this works... The DNA comes from the
         | egg, the uterus (aka womb) is just an incubation chamber.
         | 
         | Would only have the sister's DNA if it was an ovary transplant.
        
           | mschuster91 wrote:
           | > Would only have the sister's DNA if it was an ovary
           | transplant.
           | 
           | Fun fact: fetal cells transmit back to the mother and can be
           | spotted in virtually every organ afterwards - it's called
           | "Fetomaternal cell microchimerism" [1].
           | 
           | It's not a far stretch to assume the transfer works also the
           | other way around and you can detect maternal DNA in the
           | fetus/child, but I'm not aware if there has been research
           | around that.
           | 
           | [1] https://www.sciencedirect.com/science/article/pii/S138357
           | 422...
        
             | veidr wrote:
             | Yep, mom-fetus/child is "maternal microchimerism" and it is
             | also widely studied (though less so than the reverse) and
             | seemingly confirmed.
        
       | amarant wrote:
       | I can't help but wonder if there is any hope of this working for
       | trans persons in the future?
       | 
       | Could someone born as a man have a transplanted womb and get
       | pregnant through in-vitro fertilization, in theory? anyone here
       | with more medical knowledge who can comment on how likely that is
       | to work at some point in the future?
        
         | jagger27 wrote:
         | It might work with a C-section. Reassignment surgery isn't
         | stretchy enough for a live birth. For trans girls who start
         | before male puberty they might get enough pelvic rotation for
         | there to be enough room for it, though.
        
           | spondylosaurus wrote:
           | Not transfem myself, but considering the risk of tears and
           | other unpleasantness from a vaginal birth I know I'd probably
           | opt for a C-section if I were in that position regardless...
           | recovering from bottom surgery once is tough enough without
           | the miracle of life wreaking havoc on the place after :P
        
             | jagger27 wrote:
             | Yeah exactly.
        
         | spondylosaurus wrote:
         | Considering how many trans people who are assigned female at
         | birth get hysterectomies (tissue that would otherwise be
         | discarded), maybe there could be a "give a uterus, take a
         | uterus" matching program...
        
           | tredre3 wrote:
           | Maybe I'm missing the point you're trying to make but people
           | who get hysterectomies aren't doing it for fun, they're doing
           | it because the organ is diseased so giving it to someone else
           | wouldn't work.
        
             | kgwgk wrote:
             | Among those "trans people who are assigned female at birth"
             | who "get hysterectomies" how many would you say are doing
             | it because the organ is diseased. (Not that the proposal is
             | practical, of course.)
        
             | throwawayk7h wrote:
             | This is not true; trans men get hysterectomies for
             | different reasons than that it is diseased.
        
               | spondylosaurus wrote:
               | Yep, and many cis women will remove completely non-
               | diseased uteruses as a form of permanent birth control :P
        
               | ben_w wrote:
               | One woman has told me she kept asking for this, but the
               | doctors kept refusing "in case [she] want[s] kids later".
               | 
               | As you may imagine, she was not happy with such
               | responses.
        
         | thrance wrote:
         | Apparently [1], it's not completely out of the question, but
         | more research is needed before it can be safely attempted on a
         | trans woman.
         | 
         | However, I fear the largest hurdle will be a political one,
         | with so many nutjobs [2] so hell-bent on imposing their
         | dogmatic definition of gender on everyone.
         | 
         | [1] https://www.euronews.com/health/2023/08/23/uterus-
         | transplant...
         | 
         | [2] https://www.theguardian.com/books/2025/apr/18/jk-rowling-
         | har...
        
           | Thorentis wrote:
           | Ah yes, the nut jobs are the ones opposing what for almost
           | all of human history, is something so far beyond the
           | imagination as to be bordering on the grotesque.
        
             | thrance wrote:
             | What historical "truth" are you defending? Flat earth?
             | Racism? You're being a bit vague.
             | 
             | If you couldn't tell, that was a jab at your appeal to
             | tradition.
        
               | Spivak wrote:
               | I always find it fascinating where people draw off the
               | line at natural given modern life is closer to "life in
               | plastic" than anything resembling nature. We stole fire
               | from the gods, domesticated ourselves via agriculture,
               | reshaped the world in our image, and have literally slain
               | two of the four horsemen.
        
               | thrance wrote:
               | Thank you, you worded an idea I carried in my head for a
               | while. Our world can hardly be considered "natural"
               | anymore.
        
             | alxjrvs wrote:
             | > what for almost all of human history, is something so far
             | beyond the imagination as to be bordering on the grotesque.
             | 
             | Citation needed
        
             | LadyCailin wrote:
             | You mean grotesque things like artificial insulin for
             | making type 1 diabetes not a death sentence? Don't confuse
             | your own personal bigotry and small mindedness with what
             | should be considered "grotesque".
        
               | Thorentis wrote:
               | Artificial insulin is akin to medicine, potions, etc, I
               | don't think anybody would consider this grotesque at any
               | point in time
        
               | thrance wrote:
               | Jehovah's Witnesses?
               | 
               | Transition is also a medical treatment, it is used to
               | treat gender dysphoria, as the only remedy we know to be
               | effective.
               | 
               | If you feel like documenting yourself out of your
               | ignorance (I doubt you will but who knows), here are some
               | pointers. You can check each claim I make against the
               | numerous studies and metastudies on the subject.
               | 
               | * Gender dysphoria is real and touches a non-trivial part
               | of the population.
               | 
               | * Gender dysphoria poses significant hazard to mental
               | health and can lead to suicide.
               | 
               | * Gender dysphoria almost never goes away, and when it
               | does, it's mostly from external pressures on the
               | individual (religious, political). In which cases, the
               | individual keeps most symptoms (depression...).
               | 
               | * Transition effectively cures gender dysphoria.
               | 
               | * Very few people regret transitioning (<1%).
        
         | throw_m239339 wrote:
         | > I can't help but wonder if there is any hope of this working
         | for trans persons in the future?
         | 
         | why just trans? it would work on any male regardless of what
         | they identify as if it were possible. No need for penis removal
         | either, C-section would work.
        
           | thrance wrote:
           | I guess trans women would have more of a desire to give birth
           | than men. As one of the latter, I don't particularly seek
           | experiencing child-bearing.
        
             | throw_m239339 wrote:
             | > I guess trans women would have more of a desire to give
             | birth than men.
             | 
             | No, since plenty of trans men have babies. All these
             | considerations would be completely irrelevant.
        
               | throwawayk7h wrote:
               | Trans men having babies is not strong evidence for cis
               | men having less of a desire to give birth than trans
               | women. If you have the equipment for it, it's going to
               | happen some percent of the time.
        
               | throw_m239339 wrote:
               | > Trans men having babies is not strong evidence for cis
               | men having less of a desire to give birth than trans
               | women. If you have the equipment for it, it's going to
               | happen some percent of the time.
               | 
               | It's strong evidence that the desire to birth child has
               | nothing to do with gender identity, which latter will be
               | pretty much pointless by the time science allows human
               | foetus gestation outside the human female body.
        
           | aisenik wrote:
           | Unless the procedure has changed dramatically, it requires a
           | functional vagina. Neovaginas are qualified but I would not
           | expect most male-identified people to opt for vaginoplasty.
        
             | throw_m239339 wrote:
             | > Unless the procedure has changed dramatically, it
             | requires a functional vagina. Neovaginas are qualified but
             | I would not expect most male-identified people to opt for
             | vaginoplasty.
             | 
             | First, male-identified people can be born biological
             | female. It's an identity.
             | 
             | Second, the procedure doesn't exist for biological males to
             | begin with right now, neovagina or not. A neovagina is
             | physiologically not a biological female vagina to begin
             | with anyway so I wouldn't help at all with the gestation.
             | Birth can be done via C-Section.
        
               | aisenik wrote:
               | You'll be surprised to learn that neovaginas are also
               | possessed by cis women. Trans men requiring vaginoplasty
               | and receiving a uterine transplant are the nichest
               | possible edge case, your "gotcha" is pure distraction.
               | 
               | Trans women will receive the modern* uterine transplant
               | operation, this I can state with certainty. Birth _is_
               | done via C-section as a requirement of the UTx operation,
               | the vagina is required for discharge. I haven 't been
               | able to pay attention to the operation for a few years,
               | but it is clear that you are operating from uninformed
               | conjecture.
               | 
               | *The first uterine transplant was performed on a trans
               | woman in Germany in 1930, Lili Elbe. This pioneering
               | surgery lead to her death, as transplantation medicine
               | was not adequately developed at that point in time.
        
               | throw_m239339 wrote:
               | > You'll be surprised to learn that neovaginas are also
               | possessed by cis women. Trans men requiring vaginoplasty
               | and receiving a uterine transplant are the nichest
               | possible edge case, your "gotcha" is pure distraction.
               | 
               | > Trans women will receive the modern* uterine transplant
               | operation, this I can state with certainty. Birth is done
               | via C-section as a requirement of the UTx operation, the
               | vagina is required for discharge. I haven't been able to
               | pay attention to the operation for a few years, but it is
               | clear that you are operating from uninformed conjecture.
               | 
               | > *The first uterine transplant was performed on a trans
               | woman in Germany in 1930, Lili Elbe. This pioneering
               | surgery lead to her death, as transplantation medicine
               | was not adequately developed at that point in time.
               | 
               | Not all transmen require a vaginoplasty, not all
               | transwomen have had a vaginoplasty or even have the
               | desire to do so.
               | 
               | No biological male has ever birthed a child so far, so
               | all that's speculation about what is or isn't needed from
               | you is just that, speculation, based on nothing since
               | it's technically not possible for now.
               | 
               | The desire to birth a child doesn't depends on anybody's
               | gender identity nor anatomy.
               | 
               | Now stop trying to put people in boxes and keep an open
               | mind.
        
         | drooby wrote:
         | I would suspect this is extremely dangerous. The female genome
         | is intricately evolved to handle the hormone war of pregnancy.
        
           | thrance wrote:
           | Are you an expert in the field? All I've read so far on the
           | subject induicates that it should be doable in the near
           | future.
        
             | staunton wrote:
             | Any sources you would recommend?
        
         | aaaja wrote:
         | What would be the point of that? I'd be surprised if it got
         | past an ethics committee.
         | 
         | Aside from this, the male pelvis isn't shaped to accommodate a
         | womb, and males don't have the hormonal milieu to enable
         | pregnancy.
         | 
         | The closest that researchers have come to having a male gestate
         | a foetus was in rats. But they had to connect the bloodstream
         | of the male rat to a pregnant female rat, where both were
         | implanted with embryos at the same time. Even then, it worked
         | less than 5% of the time.
        
           | derektank wrote:
           | Presumably, the point would be that a trans woman wanted to
           | have kids without using a surrogate (which some people have
           | ethical qualms with)
        
         | bobsmooth wrote:
         | "You will live to see man-made horrors beyond your
         | comprehension."
        
           | throwawayk7h wrote:
           | That's a very negative attitude. Think about how happy these
           | women must be to have this procedure done. Just because
           | something isn't natural doesn't mean it's horrible.
        
             | bobsmooth wrote:
             | I'm all for giving nature the middle finger but maybe we've
             | gone too far.
        
               | Krssst wrote:
               | Harmful divergence from nature: man-made climate change.
               | 
               | Harmless divergence from nature: helping women have
               | children.
        
               | rrgok wrote:
               | Harmless is yet to be seen, right?
        
           | Melonai wrote:
           | It's interesting how something that seems both incredible to
           | me and genuinely gives me hope for the future of myself and
           | many others can be viewed by others as horrific and a
           | perversion, although I am a bit saddened to think about it.
           | 
           | People's perspectives give wildly different views on things.
        
           | aisenik wrote:
           | I can totally comprehend trans women having babies. Heck, I
           | can comprehend cis men having babies: Arnold Schwarzenegger
           | did it in the 90s.
           | 
           | I can't truly comprehend the mass data collection and
           | surveillance system, how it interplays with intelligence and
           | law enforcement, and what the impact of connecting a global
           | constellation of privatized armed satellites and a
           | constellation of advanced phased array antennas & sdrs to
           | either end of the system will be, however. I believe there
           | are bigger threats to humanity than bodily autonomy.
        
         | aisenik wrote:
         | I've had my eye on the UTx op for the better part of the
         | decade. It is my understanding that there's no medical reason
         | to expect it would not be successful in a trans woman. I don't
         | have recent numbers but we passed >100 uterine transplants a
         | while back. The most complicated physical requirement is a
         | functional vagina for discharge (which is generally on the
         | roadmap for trans women interested in carrying a child).
         | 
         | I am unaware of trans women having received this operation yet,
         | but Lili Elbe died after the first uterine transplant nearly
         | 100 years ago, before the Nazi regime destroyed trans medicine
         | and eradicated contemporary trans existence. Given the global
         | climate, I don't expect any trans recipients to be eager for
         | publicity. It will happen, and soon.
        
       | veidr wrote:
       | Glad for this family, but also:
       | 
       | This is interesting to me at the margins, because one of the
       | things I learned when my wife got pregnant the first time was
       | that the womb is not exactly the warm cradle of nurturing that I
       | had always (without thinking much about it) imagined, but in many
       | ways a blast door or containment vessel to protect the mother
       | (host) from the fetus (roughly, xenomorph) that would otherwise
       | explode like an aggressive parasite (killing them both).
       | 
       | So I mean, you probably don't want to have any leaks or weak
       | stitches in your uterus transplant...
       | 
       | Keywords: fetal microchimerism, placental barrier, trophoblast
       | invasion
        
         | hinkley wrote:
         | They also check the blood type of the baby and the mother and I
         | believe this is to make sure the mother won't throw clots, and
         | to take precautions if there's a mismatch.
        
         | tommica wrote:
         | This is at the same time the most horrible description of what
         | is going on, and the most hilarious :D "roughly, xenomorph"
         | really got me!
        
           | ben_w wrote:
           | There is, famously, an alternative reading of the Alien
           | franchise where it's about a non-consensual pregnancy in a
           | society that forbids abortions.
        
             | CPLX wrote:
             | Pretty sure that's not some fringe theory. Didn't the
             | director and visual designers consciously use rape as the
             | model for how to depict the Alien attacks?
        
         | anvandare wrote:
         | Pregnancy is, it seems, just another (evolutionary) war.
         | 
         | https://aeon.co/essays/why-pregnancy-is-a-biological-war-bet...
         | 
         | Red in tooth and claw at every layer, from the smallest cell to
         | the entire biosphere.
        
           | sitkack wrote:
           | > It's no accident that many of the same genes active in
           | embryonic development have been implicated in cancer.
           | Pregnancy is a lot more like war than we might care to admit.
           | 
           | Amazing article. Another reason that hardshelled laid eggs
           | are such a great invention. The offspring can do its thing
           | from a safe distance.
        
             | andai wrote:
             | The article suggests the external egg also limits the
             | creature to a small brain.
        
               | nine_k wrote:
               | Birds, the inheritors of the venerable Dinosaur brand,
               | managed to both produce very large eggs (e.g. ostriches),
               | and impressively capable brains, rivaling those of larger
               | mammalians (e.g. parrots, corvids), interestingly,
               | without the use of very large eggs.
        
               | c22 wrote:
               | Okay, crows are impressive. But I'm not going to let one
               | do my taxes.
        
               | throw-qqqqq wrote:
               | The crow wouldn't let you build its nest either
               | -\\_(tsu)_/-
        
               | mort96 wrote:
               | No, but humans would be capable of making something which
               | could serve as a crow's nest, while a crow wouldn't be
               | able to do taxes if we let it...
        
               | throw-qqqqq wrote:
               | Are you sure? I would be very surprised if a human could
               | build a nest that a crow would accept unaltered.
               | 
               | Most birds' nests are built much more intricately than
               | just a pile of sticks thrown together! Usually built from
               | layers of different materials, sometimes weaved or
               | plastered with mud/clay/bird-spit.
               | 
               | E.g. sparrows pick up lavender in my garden, because the
               | oils repel some pests etc.
        
               | thih9 wrote:
               | Not doing taxes is a plus for corvids in my book.
               | Seriously, you picked one of the least impressive human
               | activities. Makes me think about my potential
               | reincarnation choices.
               | 
               | Crows fly, mate for life and are considered positive for
               | the ecosystem. Humans do taxes.
        
               | ekianjo wrote:
               | Still nothing remotely close to a human brain.
        
               | alganet wrote:
               | That seems about right according to research.
               | 
               | There are many articles about bird intelligence available
               | from multiple sources.
               | 
               | A more open minded perspective would instead try to look
               | to what is "remotely close" to a human brain.
               | 
               | Although primates can't quite communicate like humans,
               | they are known for being our closest relatives in
               | scientific biological terms.
               | 
               | I know I am deviating from the birds subject a little,
               | but stick with me. I need to address the "remotely close"
               | expression you used.
               | 
               | Primates can display what humans would recognize as human
               | behavior. Work in groups, social dynamics, use of simple
               | tools.
               | 
               | The "looks like human" effect could be explained by
               | anthropomorphization performed by those very humans (to
               | put it simply: an effect where humans see human features
               | in non human things). In fact, some behaviors considered
               | as human are not commonly displayed by primates, like the
               | ability to keep a pet. There is no clear definitive
               | answer to it, and any dismissal of such behaviors could
               | be also used to dismiss humans themselves, therefore I
               | must refrain from entertaining them too much.
               | 
               | Birds also show a lot of human like behavior. Like the
               | ability to gather objects (to construct a nest and to
               | attract a partner are common examples).
               | 
               | Remember, the closest thing to humans in anatomy and
               | biology (primates) is not very much different from birds
               | in terms of "how it presents human-like" behavior.
               | 
               | So, as a counter argument, I would ask: what makes the
               | difference of thinking between a primate and a bird so
               | different to you? Is it their anatomy that prevents you
               | from anthropomorphizing it so readily? Or do you also
               | think primate brains are "nothing remotely close to a
               | human brain"?
               | 
               | It cannot be denied that "closeness" is a loose
               | definition and could generate endless discussion. I tried
               | to concede a little bit to find a reasonable common
               | ground that is both based on rational thinking and a
               | little bit of open mindedness.
               | 
               | Under such criteria, I can assert that birds might be
               | much more intelligent than previously assumed.
        
               | disqard wrote:
               | Thoughtful (and thought-provoking) comments like yours
               | are why I frequent this site.
               | 
               | Thank you, stranger!
               | 
               | For my part, I'll add that "Humans are visual creatures",
               | which biases every aspect of our culture -- and might
               | help explain why many would consider other primates
               | "closer" to us than birds.
        
               | ekianjo wrote:
               | Thanks for your answer. Let me elaborate a little bit.
               | What diffentiates humans from most animals is not about
               | solving complex puzzles (some birds are able to do that)
               | or be able to learn things (birds and primates can do
               | that as well) but in the ability of humans to plan for
               | the future. As far as I know (but do correct me if you
               | have better information) there is no animal that
               | exhibits:
               | 
               | 1) the ability to plan ahead of time 2) in a non innate
               | way
               | 
               | The consequence is that humans actually build stuff by
               | investing time and energy by visualizing a future benefit
               | without immediate gratification. I believe this is unique
               | in the realm of animals, at least for now.
        
               | alganet wrote:
               | Primates do display acquired learning. Like the knowledge
               | to hunt ants with sticks. A non innate ability that
               | requires planning and is passed along to members of the
               | same social group.
               | 
               | It has been reported that some eagles and hawks spread
               | fire to drive out prey from dense vegetation. Whether
               | that is learned behavior and planning for the future, a
               | previously undiscovered innate behavior, or just a myth,
               | depends on results of further research.
               | 
               | Whales wearing salmon hats is a story that, if happens to
               | be true, would also be a non-innate behavior, whose
               | purpose we don't know, that could point to something
               | close to what you described.
               | 
               | Humans are different, I cannot disagree.
               | 
               | My play was to challenge our assumptions of what that
               | perceived distance from humans to animals is consisted
               | of.
               | 
               | We can come up with increasingly more convoluted ways of
               | defining what we are. Animals can't. Maybe that is our
               | innate ability.
        
               | __s wrote:
               | Also amazing with birds is how effectively they've
               | evolved intelligence with a small brain
               | 
               | https://medicalxpress.com/news/2016-06-term-bird-
               | brain.html
        
               | sitkack wrote:
               | We overfocus on brain volume, when we should be
               | calculating the number of neurons and neuron size varies
               | wildly.
               | 
               | I can't find the original video, but Suzana Herculano-
               | Houzel developed a technique to measure total neuron
               | counts by liquefying the brain and then counting the cell
               | nucleus density / volume.
               | 
               | WSU Master Class: Big Brains, Small Brains with Suzana
               | Herculano-Houzel
               | https://www.youtube.com/watch?v=rDM3TcfGoBY
               | 
               | (nice short popsci intro) The woman who turns brains into
               | soup: Suzana Herculano-Houzel
               | https://youtu.be/d2Uhv0_Ji1k?t=362 (talks about racoon
               | and bird brains)
               | 
               | https://news.vanderbilt.edu/2017/09/07/brainiac-with-her-
               | inn...
               | 
               | https://hn.algolia.com/?dateRange=all&page=0&prefix=false
               | &qu...
               | 
               | This paper is really fun, "Brains matter, bodies maybe
               | not: the case for examining neuron numbers irrespective
               | of body size"
               | https://www.semanticscholar.org/paper/Brains-
               | matter%2C-bodie...
        
               | pragma_x wrote:
               | It's something to marvel at, really. Birds _needed_ to
               | evolve super efficient brains due to all the constraints
               | that flight puts on the organism; they have to be more
               | efficient by weight as well as by size. Meanwhile, being
               | earthbound like you or I lets our DNA get away with a lot
               | more slop.
        
           | petermcneeley wrote:
           | The baby probably does not benefit from the death of the
           | mother.
        
             | tgv wrote:
             | But some form of evolution might make it a local optimum.
             | It would at least require 3 or more offspring per
             | pregnancy, and could not happen in mammals, though.
        
               | petermcneeley wrote:
               | Much harder than that. All mammals drink milk.
        
               | worik wrote:
               | > All mammals drink milk.
               | 
               | I don't
        
               | ben_w wrote:
               | If that was true when you were an infant, you're part of
               | an extreme minority.
               | 
               | You would not have survived more than a few weeks past
               | birth in the absence of modern medical interventions --
               | well, that part at least was true for most of us -- but
               | specifically an inability to process milk as an infant is
               | very rare, precisely because "mammary" is what puts the
               | "mam" in "mammal".
        
               | thaumasiotes wrote:
               | > precisely because "mammary" is what puts the "mam" in
               | "mammal"
               | 
               | It puts the "mamm" in; that second _m_ is also part of
               | the root.
        
               | c22 wrote:
               | As is the third _m_.
        
               | koakuma-chan wrote:
               | The word "mammary" contains two "m's." (c) ChatGPT
        
               | thaumasiotes wrote:
               | It contains one _m_ and one double _m_. They 're distinct
               | concepts.
        
               | echelon wrote:
               | I get downvoted every time I feel like posting this (the
               | thread is markedly appropriate), so I'll give some
               | background this time. I'll get to the point after a
               | little bit of setup.
               | 
               | To segue from your post, I was adopted as an only child
               | at birth, so formula was the only option. No IgA
               | exposure, which probably over-taxed my early immune
               | system.
               | 
               | But in being adopted, I have very nontraditional feelings
               | about cloning, artificial birth, etc. I knew about my
               | adoption from an early age, so it deeply worked itself
               | into my thinking. At about elementary school age, some of
               | my asshole neighbors bullied and called me a bastard, but
               | that didn't really impact me as much as the feeling of
               | being a genetic island completely alien to everyone else.
               | All of my peers were related to their birthing parents
               | and sometimes clonal siblings, yet I was alone in the
               | universe. My weird hobbies and behaviors and preferences
               | were out of the norm for my family. Despite my closeness
               | with them, I didn't feel the same as everyone else around
               | me. I wasn't. I was a nerd, absorbed into science books
               | and Bill Nye. The southern culture and football and
               | Christian God I grew up around wasn't my home, and I
               | couldn't understand it just as others couldn't understand
               | me. Everyone talks about blood as being a big deal - it's
               | even in the foundation of the religion I was raised in -
               | but to me, it meant nothing. It really shaped how I feel
               | about humanity and biology and families and reproduction
               | and the universe. Ideas, not nucleotides, are the
               | information that matters.
               | 
               | I've understated and undersold how fundamentally
               | differently this makes me feel about people.
               | 
               | Because of my perspective, I have controversial
               | viewpoints about human biology. I don't find them weird
               | at all, but there's a good chance it'll offend you:
               | 
               | If we can ever get over the societal (religious?) ick
               | factor, perhaps we could one day clone MHC-negative,
               | O-negative, etc. monoclonal human bodies in artificial
               | wombs. Use genetic engineering to de-encephalize the
               | brain, and artificially innervate the spine and
               | musculature. We'd have a perfect platform for every kind
               | of organ and tissue transplant, large scale controlled in
               | situ studies, human knockouts, and potentially crazy
               | things like whole head transplants to effectively cure
               | all cancers and aging diseases except brain cancers and
               | neurodegeneration.
               | 
               | Because they're clones engineered to not expose antigens,
               | their tissues could be transplanted into us just like
               | plants being grafted. No immunosuppressants. This might
               | become the default way to cure diseases in the future. We
               | could even engineer bodies that increase our
               | physiological capacity. Increased endurance, VO2 max,
               | younger age, different sex, skin color, transgenic
               | features. Alien hair colors. You name it.
               | 
               | I bring things like this up and get ostracized and
               | criticized. But it feels completely normal to me. Our
               | bodies are machines. We should do everything we can to
               | repair them and make them better. It appalls me that we
               | aren't making progress here.
               | 
               | In light of how others think, I don't think I'd have
               | these thoughts so comfortably if I didn't feel like
               | something of a clone already. A genetic reject, an
               | extraterrestrial growing up, tends to think differently.
               | 
               | Flipping this around, your aversion to this is because
               | you have a mother and father that birthed you that you
               | share blood with. That you grew up in a god fearing
               | society bathed in his sacrificial blood. If you were like
               | me, perhaps you'd think like me.
               | 
               | I'm totally perplexed that other people find this
               | disgusting or horrifying. It feels wholly natural.
               | 
               | And we should absolutely do it.
        
               | petermcneeley wrote:
               | Terry?
        
               | TimTheTinker wrote:
               | Have you ever seen the movie "The Island"? I'm curious
               | what your reaction to it would be.
               | 
               | > If we can ever get over the societal (religious?) ick
               | factor
               | 
               | I believe those kinds of "ick" factors are there for a
               | reason - protecting us from a descent into deep dystopia
               | or something.
               | 
               | Implementing new human things at scale often has
               | unanticipated indirect negative consequences.
        
               | echelon wrote:
               | > Have you ever seen the movie "The Island"? I'm curious
               | what your reaction to it would be.
               | 
               | It's a typical Hollywood sci-fi film with the usual
               | Hollywood lessons and platitudes.
               | 
               | We wouldn't be producing clones with brains or
               | consciousness. We might even have to modify the spine and
               | stomach.
               | 
               | So there's no thinking at all. They'd be like plants.
        
               | ben_w wrote:
               | I think that in this case, the ick factor is because
               | evolved traits can only work with relatively simple
               | patterns.
               | 
               | My guess is for many of us, our gut says "looks like a
               | human therefore is human"; if you try to tell gut
               | instinct it's fine because there's no brain, you're gut's
               | response is "Brain and brain! What is brain?"
               | 
               | My gut seems to care more about dynamic behaviour than
               | static appearance, but for what it's worth -- and despite
               | being able to understand the premise of @echelon's
               | suggestion without being upset by it -- even I find
               | images of a real, natural, human birth defect where the
               | brain is missing, to be horrifying (content warning: do
               | not google "anencephaly" unless you're strong stomached).
        
               | throaway1989 wrote:
               | Most of the ick factors are because of our empathy, which
               | triggers upon seeing another human being in "icky" states
               | of being and makes us imagine what it would feel like to
               | be in such a state.
        
               | aaaja wrote:
               | Have you found that other adoptees feel similarly about
               | or at least are more sympathetic to your ideas?
        
               | achenet wrote:
               | > Our bodies are machines. We should do everything we can
               | to repair them and make them better. It appalls me that
               | we aren't making progress here.
               | 
               | unlike man-made machines, we do not fully understand our
               | bodies yet, and as such should be careful when trying to
               | make them better. Don't start randomly `rf -rf *` on a
               | Unix system if you don't know what it does, don't start
               | randomly using steroids if you aren't sure of the long
               | term biological consequences.
               | 
               | Obviously, your proposed "monoclonal human bodies in
               | artificial wombs" would help with that.
               | 
               | If you'll also allow me a quick remark on your
               | upbringing, as someone from an intellectual Parisian
               | family who grew up in God-fearing, football-loving
               | Texas...
               | 
               | I'm sure that somewhere in the South, there is a little
               | gay kid, or one born with an odd mutation, to his birth
               | parents, who felt or feels the exact same way you did -
               | as something of an alien. I believe that the vast
               | majority of cultures will produce outsiders, and it's
               | also very probable that somewhere in Paris, there is
               | someone who doesn't feel at home in the midst of heavy
               | intellectual conversation and would prefer a simpler
               | world focused on traditional religion and football
               | (possibly association football/soccer, rather than
               | American football).
               | 
               | Humans can form 'tribes', in the loosest sense of the
               | word possible, based on genetics, but we also form tribes
               | based on similar beliefs, values and interests - for
               | example, Hacker News :)
        
               | echelon wrote:
               | > Humans can form 'tribes', in the loosest sense of the
               | word possible, based on genetics, but we also form tribes
               | based on similar beliefs, values and interests - for
               | example, Hacker News :)
               | 
               | I agree with this, and I'm glad we do. But I've posted
               | the "let's harvest clones for organs" idea numerous times
               | on HN -- a community where many of us are on somewhat of
               | a similar wavelength. It's usually met with a lot of
               | vitriol and disgust.
               | 
               | > Obviously, your proposed "monoclonal human bodies in
               | artificial wombs" would help with that.
               | 
               | That's one of the nice things about this. It would give
               | us an organismal research platform where we could
               | replicate experiments. No more animal studies, imperfect
               | chimera systems, or molecular experiments we can't scale
               | up. We'd have a perfect test bed for investigating almost
               | everything that ails us.
        
               | ben_w wrote:
               | > I don't find them weird at all, but there's a good
               | chance it'll offend you:
               | 
               | It does not offend me. I cannot say if I would be upset
               | if this were to be turned from idea to reality because
               | the closest thing in reality is quite upsetting; but
               | because I think that the only part of a body capable of
               | suffering is the CNS, I also regard any potential upset
               | on my part about a realisation of your idea as a "me
               | problem", not a "you problem".
               | 
               | That said, I don't know how far we are from being able to
               | perfom what you suggest, even in principle.
               | 
               | It may well be the case that growing a full human without
               | a CNS is harder than solving 3D bioprinting.
               | 
               | One downside of such a degree of biological mastery, is
               | that it does to trust in real life what AI is currently
               | doing to trust online.
        
               | vacuity wrote:
               | On a general note, if this feels natural and right to
               | you, don't be quick to dismiss others' views as having
               | less substance or credibility and being conditioned. But
               | I appreciate that you earnestly believe this, and for
               | that there is nothing _prima facie_ wrong with your view
               | either.
               | 
               | > Our bodies are machines. We should do everything we can
               | to repair them and make them better. It appalls me that
               | we aren't making progress here.
               | 
               | I feel like this is not obvious. Many people seem to want
               | to enjoy life more than anything else, and if this
               | biotech means curing cancer so they can do so for longer,
               | sure, but at some point it may be too invasive. Like if
               | you have to undergo a procedure every year to get
               | diminishing returns. A lot of the features you mention
               | are nice to have, but not strongly appealing to me
               | personally. Particularly for something like immortality:
               | if I'm going to have that, I want a lot of other things
               | too that biotech won't obtain.
               | 
               | Also, at that level of biotech, it seems like we could
               | forgo the clones and enhance our bodies directly. That
               | would remove the ethical concerns of cloning, in
               | particular the notion of creating clones for our own
               | purposes instead of letting them reach their own. Beliefs
               | that boil down to "I was here first" or "I beat you" are
               | common, but I find them problematic.
               | 
               | Birth/creation is a fascinating philosophical topic. I
               | have a radical view which isn't quite "life is suffering
               | so being born is a net harm", but I think that life is
               | not all that valuable. I won't go out of my way to harm
               | existing life, but I'm not sure I should go out of my way
               | to accomodate new life. If humans all died off naturally,
               | would that be such a bad thing? Life is great, but it's
               | not _that_ great. If we do gain cloning technology, I
               | think we should afford clones the potential to do as they
               | will, just as we want for ourselves. Again, we could
               | probably obviate clones for the purposes you see.
        
             | spwa4 wrote:
             | That depends. Look it up. You will find there is a point
             | where it switches. Normally the body (of both baby and
             | mother) will protect the mother. Something goes wrong or
             | just gets too far "out of spec"? Miscarriage. After a few
             | months, the body goes so far as to sedate the mother and
             | child before terminating the pregnancy. There is research
             | claiming it actually shuts down the baby's nervous system
             | before decoupling.
             | 
             | But about a month before birth things switch around. The
             | womb partially disconnects from control systems of the
             | mother's body and ... there's an extremely scary way of
             | pointing this out I once heard from a medical professor:
             | "you know just about the only thing a human body can still
             | do when it's decapitated? It can give birth"
             | 
             | In less extreme circumstances, you actually have a switch
             | in your circulatory system ... when pregnancy gets to this
             | point and the mother's body loses power, it will initiate a
             | rapid birthing process, and start shutting down organ after
             | organ to give birth with the remaining power. That
             | includes, eventually, the brain. Only the heart, lungs,
             | liver and womb will remain operational. The body will shut
             | down blood flow to the brain to continue giving birth. Once
             | shut down it cannot be turned back on. So this kills the
             | mother, despite the body remaining functional, in some
             | reported cases, for over an hour, and is something
             | gynaecologists get trained to prevent from happening.
             | 
             | Given how common it was even a century ago for women to die
             | giving birth, one wonders how often this mechanism was
             | involved.
        
               | andai wrote:
               | Ah, a bit of light bedtime reading... I should really
               | turn off my phone before going to bed.
        
               | klipt wrote:
               | No sources provided and internet failed to confirm ...
               | closest I found was
               | 
               | > In extremely rare forensic cases, a phenomenon called
               | "coffin birth" (post-mortem fetal extrusion) can occur,
               | where gases from decomposition expel a fetus from the
               | deceased mother's body. This is not true childbirth and
               | is extremely rare, occurring only under specific post-
               | mortem conditions.
        
               | spwa4 wrote:
               | Oh come on, any medical text will confirm that the womb
               | has it's own nervous system and blood supply and a good
               | text will tell you that the system will function
               | correctly in even completely paralyzed women. Just how do
               | you think that works? And any text will SCREAM at you to
               | keep a constant eye on the woman giving birth: if they
               | stop breathing IT WILL NOT stop the birth, rather it will
               | cause severe symptoms afterwards. A gynaecologist is not
               | telling women to breathe to calm them down.
               | 
               | The blood supply and nerves are weird special cases in a
               | great many ways. For instance, they're not left-right
               | symmetric (whereas the ones of "nearby" systems, like the
               | bladder, are. So this was not done because there's only
               | one womb)
        
               | serf wrote:
               | >a good text will tell you that the system will function
               | correctly in even completely paralyzed women. Just how do
               | you think that works?
               | 
               | the body has a lot of messaging systems; 'completely
               | paralyzed' people still enjoy the use of many chemical
               | messaging signals; they just generally have a hindered
               | spinal cord or neurological interface element.
               | 
               | A paralyzed person will still go into shock after a
               | dismemberment, blood-flow will be affected by vaso-
               | constriction, and so on. It doesn't surprise me to hear
               | that childbirth can trigger a similar set of conditions
               | to occur.
               | 
               | And that belittles the existence of the underlying
               | support nervous system and the secondary elements. Many
               | completely paralyzed men can achieve erection and
               | ejaculation even with a near total disconnect from the
               | rest of the nervous system. Why? The parasympathetic
               | nervous system and secondary nervous materials in the
               | region in question are taking up the slack from the brain
               | and still allowing 'normal' function.
        
           | andai wrote:
           | My uncle said yesterday that man's harsh nature goes back to
           | Rome: Homo homini lupus.
           | 
           | The article says it goes back a lot further than Rome!
           | 
           | > So if it's a fight, what started it? The original bone of
           | contention is this: you and your nearest relatives are not
           | genetically identical. In the nature of things, this means
           | that you are in competition. And because you live in the same
           | environment, your closest relations are actually your most
           | immediate rivals.
        
             | thaumasiotes wrote:
             | > My uncle said yesterday that man's harsh nature goes back
             | to Rome: Homo homini lupus.
             | 
             | What's "homini" supposed to mean?
        
               | dragonwriter wrote:
               | _Homini_ is the dative of _homo_ , meaning roughly "to
               | (a) man".
               | 
               | The phrase is a latin proverb meaning, roughly, "A man is
               | a wolf to another man".
        
               | azmodeus wrote:
               | Man man's wolf Homo homini lupus
        
               | n3storm wrote:
               | Homo homini lupus is the latin for "Man is wolf for man",
               | famous quote from Plautus.
               | 
               | Homini is the declination of Homo, is dative case. I
               | don't know how to properly translate dative to english,
               | something like "to give".
               | 
               | I know this from Philosophy and Latin (separate) in
               | Highschool around the nineties in Spain. They both were
               | compulsory global subjects. I think Latin is not
               | compulsory this days.
        
               | thaumasiotes wrote:
               | > famous quote from Plautus
               | 
               | The quote from Plautus appears to be _lupus est homo
               | homini_ , which is much easier to parse. There's a verb
               | and everything. (I didn't know that; I just looked it
               | up.)
               | 
               | > I don't know how to properly translate dative to
               | english, something like "to give".
               | 
               | Yes, the word literally means "giving [case]", but the
               | grammatical concept in English is generally called
               | "indirect object". English mostly doesn't have cases, so
               | supplemental arguments to verbs tend to be marked by
               | associated prepositions, making them "indirect".
               | 
               | When talking about Latin specifically or languages with
               | noun case in general, it is normal in English to refer to
               | the "dative case"; you don't really need to translate it.
               | 
               | I assume the case was named after the action of giving
               | because giving is a very common action that necessarily
               | involves three things. (Giver, gift, and recipient.) The
               | name tells you what it means by example: "if a gift is
               | given, the dative case is the one you'd use for the
               | recipient".
        
               | anal_reactor wrote:
               | > Homo homini lupus
               | 
               | And kiwi kiwi kiwi.
               | 
               | Couldn't help myself, being a speaker of a language with
               | grammatical cases, which allows the translation of "homo
               | homini lupus" without changing the grammatical structure.
               | At the same time, some loanwords escape the declination
               | system, giving birth to the joke above.
        
             | wahern wrote:
             | In all non-human species selfless cooperation falls off a
             | cliff beyond siblings, and AFAIU this comports well with
             | Game Theory-type models for understanding genetics. Popular
             | examples of non-human cooperation, naked mole rates and
             | bonobos, actually live in communities dominated by sisters.
             | (It's not often noted, though, in the breathless narratives
             | extolling the virtues of cooperation and anthropomorphizing
             | the rest of the animal kingdom.)
             | 
             | Human behavior, however, is still a deep, deep mystery in
             | terms of evolutionary biology. I'm always wary of people
             | applying evolutionary principles to human behaviors. Writ
             | large you can see contours of what we would expect to see,
             | but even then it's unclear why the boundaries are where
             | they are, or to what degree we're projecting expectations
             | into the data, etc. The speculation quotient is extreme. I
             | wouldn't put any stock into evolutionary biology-based
             | explanations for human behavior. And just as a practical
             | matter, it's not like most people would leave their most
             | hated cousin to die in a ditch; and though most people
             | wouldn't leave anyone to die in a ditch--at least, if they
             | knew that's what they were doing--I'm betting they're more
             | likely to save a cousin than a stranger.
        
               | achenet wrote:
               | my viewpoint is that the human ability to cooperate
               | effectively is why there's currently 8+ billion of us on
               | earth and chimpanzees are an endangered species.
               | 
               | Our capacity for stories and language helps us create
               | large cooperation networks, which is a unique
               | evolutionary advantage.
               | 
               | Chimps have cooperation limited to "we are genetically
               | close and you give me banana so I give you banana".
               | 
               | Humans can create something like the Roman Republic, or
               | modern nation states and corporations, based on a shared
               | set of stories and language (culture, also includes stuff
               | like rituals, socio-sexual taboos, etc), which enables
               | millions of us to collaborate together towards a common
               | goal. Which is why we're so successful as a species.
        
               | londons_explore wrote:
               | Capitalism allows thousands of people who don't know
               | eachother or even speak the same language to work
               | together to make all the components of a pencil.
               | 
               |  _All_ of those people might be selfish, yet they still
               | work together without even knowing they are doing so.
        
           | Barrin92 wrote:
           | what an odd coincidence to see David Haig mentioned in the
           | article. I just stumbled over his interview on Sean Carroll's
           | podcast a few days ago, discussing the exact same topic (http
           | s://www.preposterousuniverse.com/podcast/2020/11/30/125-...)
           | 
           |  _" And so while the cooperative outcome would be the most
           | efficient, you lead to a situation in which there are
           | conflict costs, and I think this explains why things go wrong
           | so often during pregnancy. Of course, at first sight it's
           | strange, my heart and my liver have been functioning very
           | well for for 62 years, and yet during pregnancy, you have a
           | natural process that only lasts for nine months, and yet many
           | things go wrong during it. And I would argue that the reason
           | why pregnancy doesn't work as smoothly as the normal
           | functioning of the body is that in normal bodily functioning
           | all the parts of the body are genetically identical to each
           | other and working towards survival of that body, but in
           | pregnancy, you have two different genetic individuals
           | interacting with each other and natural selection can act at
           | cross-purposes, there's a sort of politics going on, and we
           | know that politics does not always lead to efficient
           | outcomes."_
        
           | xg15 wrote:
           | > _Pregnancy is, it seems, just another (evolutionary) war._
           | 
           | I think this is a useful insight even on a higher level. For
           | evolution (if you want to anthropomorphize it), war and
           | conflict are just another set of tools in the toolbox. Where
           | humans see those as evidence of something going wrong and
           | evil to eradicated, for evolution it's "working as intended".
           | 
           | (Or, if you don't want to anthropomorphize it, an indication
           | how much of evolution and biology is just barely tamed chaos)
           | 
           | (Careful to draw conclusions for human society from this
           | though. People in the past had already seen the Darwinian
           | "struggle between the species" as a model for society, which
           | brought "Social Darwinism" and ultimately the Nazi ideology.
           | 
           | A different conclusion would be that biology is in fact not a
           | perfect ideal to aspire to, and even in the situations where
           | it "works", its factual objectives are not always the same as
           | ours. Which does give legitimacy for the endeavor to improve
           | upon it - for everyone)
        
         | Ygg2 wrote:
         | > containment vessel to protect the mother (host) from the
         | fetus (roughly, xenomorph) that would otherwise explode like an
         | aggressive parasite (killing them both).
         | 
         | You can also flip the perspective the fetus is trying to
         | survive in a hostile environment designed to strangle it. If it
         | isn't clawing for every ounce of food and air it will become a
         | miscarriage. It must interface with a system built for millenia
         | designed to kill anything that doesn't have its code.
         | 
         | In truth, it is the equilibrium that evolution has achieved.
         | Placenta must account for the most vicious fetus, and fetus
         | must account for most vicious placenta.
        
           | treve wrote:
           | I think in this metaphor the placenta is actually on the
           | fetus' side and also had the baby's DNA.
        
             | Ygg2 wrote:
             | Did you read the article? It's not. It's somewhat fighting
             | against it. Plus immune system would see baby's DNA as
             | corrupted, since half of it is just wrong.
        
               | thaumasiotes wrote:
               | > Plus immune system would see baby's DNA as corrupted
               | 
               | The immune system can't see DNA at all. It works by other
               | methods.
        
               | Ygg2 wrote:
               | True but it can detect DNA isn't the same by comparing
               | expressed proteins.
        
           | diggan wrote:
           | Not to mention when multiple fetuses are involved. It's a
           | miracle there are as many twins+ as there are.
        
         | gwerbret wrote:
         | > So I mean, you probably don't want to have any leaks or weak
         | stitches in your uterus transplant...
         | 
         | With this sort of surgery, they wouldn't be cutting into the
         | uterus (womb) itself when extracting it from the donor, but
         | instead will cut around it to remove it, along with some very
         | essential plumbing. The receiving mum will also be on
         | industrial-strength immune suppressants anyway.
         | 
         | Where you DO have to worry about leaks and weak stitches is
         | with said plumbing (uterine arteries and veins) -- they have to
         | support virtual firehoses of blood through the duration of
         | pregnancy, and their damage is one reason why a delivery can go
         | south very, very quickly. Obstetric medicine is definitely a
         | high-risk sport, which is why their malpractice insurance rates
         | are head and shoulders above any other medical specialty. But I
         | digress...
        
         | dwroberts wrote:
         | > fetal microchimerism
         | 
         | This is just a fact of reality for any women that have children
         | though.
         | 
         | Eg male chromosomes from fetuses being found in women's brains:
         | https://pmc.ncbi.nlm.nih.gov/articles/PMC3458919/
         | 
         | (I don't think this is believed to be unusual or an example of
         | 'containment failure' of the womb)
        
           | Qem wrote:
           | > Results also suggested lower prevalence (p = 0.03) and
           | concentration (p = 0.06) of male microchimerism in the brains
           | of women with Alzheimer's disease than the brains of women
           | without neurologic disease.
           | 
           | It appears it may even be protective.
        
             | HPsquared wrote:
             | It's probably the whole "lifestyle package" difference
             | between having children and not. Hard to pin down a single
             | biochemical factor in that.
        
         | mcv wrote:
         | Absolutely. From what I understand, there's been an
         | evolutionary war for resources between the womb and the
         | placenta, which is a big part of why human pregnancies are so
         | complicated and invasive compared to other mammals (because no
         | other mammal has this anywhere near as extreme as we do).
         | 
         | Why us and not other mammals? No idea.
        
           | danielbln wrote:
           | I believe it all comes down to our giant noggin/brain. It's a
           | giant resource tar pit, it's why we're born effectively
           | premature, it's why we take forever to be in any shape of
           | form self sufficient and it's why we would drain the mother
           | of all resources available if she wouldn't regulate that
           | desire to fuel our brain to the max.
           | 
           | Turns out, being the most intelligent apex comes with some
           | gestational specialities.
        
         | thaumasiotes wrote:
         | Your list of keywords is missing "ectopic pregnancy", which
         | seems like exactly the kind of issue your comment contemplates.
        
         | kccqzy wrote:
         | > not exactly the warm cradle
         | 
         | That would be the gestational sac, no?
        
       | casey2 wrote:
       | Whose baby is it? If I get a transplanted womb and have hundreds
       | of kids are they mine of the original owners? I would assume the
       | current owner, but Anglo laws tend to be completely backwards
       | when it relates to sex.
        
         | nathan_compton wrote:
         | I don't think there is any womb out there that is going to
         | produce 100 kids for you.
        
         | timthorn wrote:
         | In the UK, whoever gives birth to the child is the mother.
        
       | remarkEon wrote:
       | MRKH is inherited, which adds an additional ethnical layer to
       | this.
        
         | gadders wrote:
         | Apparently so are most of the male conditions that require ICSI
         | IVF.
        
           | remarkEon wrote:
           | Interesting, I did not know that. Makes me wonder if we're
           | compounding infertility issues into the future if this is
           | done at scale. Not saying that's right or wrong, but it's
           | worth thinking about.
        
             | qingcharles wrote:
             | Probably we are, but we're also negating them with science
             | at probably a higher rate.
        
               | remarkEon wrote:
               | Right, exactly, that's my point. We're building in a
               | dependency for future fertility on these advanced
               | techniques (again, assuming the scaling theory is true).
        
       | sneak wrote:
       | If everything scientific inquiry accomplishes is a "miracle",
       | then nothing is.
       | 
       | Is it a miracle I can go to JFK and fly through the air and be in
       | Europe for dinner?
       | 
       | It's a surgical procedure. It's cool that it worked. We don't
       | need to invoke the supernatural here, especially given the oodles
       | of hard work that went into this by very real and natural human
       | beings.
        
         | derektank wrote:
         | For my money I would say, yes, and I think Louis C.K. was right
         | when he said, "Everybody on every plane should just constantly
         | be going, 'Oh my God! Wow!' You're sitting in a chair in the
         | sky!"
        
           | sneak wrote:
           | Yes, but by that logic we should be dumbfounded with awe
           | every time we speak to turn on the lights, make a long
           | distance call, eat a fresh fruit grown on another continent,
           | or walk around after open heart surgery.
           | 
           | At some point we should just assign credit where credit is
           | due: thousands upon thousands of people working very hard for
           | many decades to make the impossible possible.
           | 
           | Our modern world is amazing, but it's not miraculous. It's
           | achievement, not supernatural.
        
       | nick238 wrote:
       | Just for clarity, "in UK" is qualifying the whole thing, not that
       | she just happened to be in the UK. A woman in Alabama had a child
       | via a uterus transplant, among other places.
        
       | jesprenj wrote:
       | > The first baby born as a result of a womb transplant was in
       | Sweden in 2014. Since then around 135 such transplants have been
       | carried out in more than a dozen countries, including the US,
       | China, France, Germany, India and Turkey. Around 65 babies have
       | been born.
       | 
       | https://www.bbc.co.uk/news/health-29485996
        
       | throwawayk7h wrote:
       | Lab-grown vaginas made from the patient's own stem-cells have
       | also been transplanted into women [1]. Hopefully soon it will be
       | possible to get the whole #!/usr/bash.
       | 
       | [1]
       | https://en.wikipedia.org/wiki/Vaginal_transplantation#Labora...
       | 
       | (I don't know why this lab stopped performing this procedure
       | though.)
        
       | throwawayk7h wrote:
       | It would be quite interesting to see how public discourse about
       | gender is affected by this, and in particular if this procedure
       | is done successfully on a transgender woman. Regardless of your
       | political outlook, it will no longer be possible to say that the
       | ability to give birth is a condition for being a woman. (And what
       | will happen should chromosome replacement become possible? It
       | seems unlikely that anyone would really invest in such a
       | procedure, but is it medically feasible?)
        
         | ericmcer wrote:
         | If the procedures got so good that a trans woman/man was
         | indistinguishable from one born that way who would still object
         | to them claiming the gender they choose, most of the arguments
         | fall apart at that point.
        
           | aisenik wrote:
           | Almost everyone who opposes trans people's existence today.
           | Opposition to trans rights is rooted in patriarchal hegemony
           | and the control of bodies. Our existence is a fundamental
           | threat to the foundational perspective of the predominant
           | power-structure in society.
           | 
           | No one does a womb-check before granting women validity. It's
           | always been a vibe thing and people who do not conform to the
           | prescribed model of existence as a man or woman are
           | constantly denied full privileges under the framework. It's
           | not just trans women getting the short end of the stick here,
           | it's everyone: men who do not embrace dominance culture or
           | otherwise display "effeminacy" are denied true Man status,
           | women who don't meet beauty standards or possess a submissive
           | demeanor are slurred as bull-dykes or the dreaded transexual.
           | 
           | This isn't an issue with any real reasonable basis for it's
           | opposition, it's a golem of pure hatred and disgust in a suit
           | vs. people who want to live full, free lives.
           | 
           | editing to add: the first known uterine transplant was
           | performed on Lili Elbe who received treatments through the
           | Institute of Sexology in Germany. The Institute was famously
           | destroyed by the Nazi regime. It's barely coincidental that
           | fascism has risen again as medical science brings this
           | technology to maturity. Trans women gave their lives for this
           | medical miracle.
        
           | mftrhu wrote:
           | They would just move to calling the procedure a violation of
           | the "natural order" - "Lovecraftian horror", "Frankenstein
           | arrangement", "something Mengele would do" - argue that it is
           | akin to rape, create conspiracy theories about uteri being
           | stolen, and/or invoke "Think of the children!"
           | 
           | I saw all of that already. Some of it in this very thread,
           | some of it on the defunct /r/GenderCritical: I remember
           | someone proposing committing suicide by volcano to keep her
           | uterus out of "male [sic] hands".
        
         | alxjrvs wrote:
         | Damn, it's almost like Gender is largely vibes and any attempt
         | to root it in a strict biological standard is as patently
         | ridiculous as it would be trying to do the same to horoscopes.
         | 
         | Giving birth is already not a precondition of being a woman, as
         | the category "infertile women" exist.
        
         | bsuvc wrote:
         | > it will no longer be possible to say that the ability to give
         | birth is a condition for being a woman
         | 
         | This "gotcha game" has become so tiresome.
        
       | smeej wrote:
       | > He told the BBC around 10 women have embryos in storage or are
       | undergoing fertility treatment, a requirement for being
       | considered for womb transplantation. Each transplant costs around
       | PS30,000, he says, and the charity has sufficient funds to do two
       | more.
       | 
       | Is this because they're not connecting the transplanted uterus to
       | the fallopian tubes or something? Or is there some other reason
       | that it wouldn't be possible to conceive the "old-fashioned way"
       | post-transplant?
       | 
       | Creating and freezing embryos otherwise seems like a very strange
       | thing for a woman to have done who has no uterus, unless she was
       | already considering surrogacy. Where was she expecting them to
       | grow?
       | 
       | Requiring the embryos to be created _before_ knowing whether the
       | womb transplant would be possible or successful seems really odd
       | to me.
        
         | saalweachter wrote:
         | Surrogacy is already a thing; stored embryos have a use without
         | womb transplants.
        
       | im3w1l wrote:
       | From an individual perspective this is absolutely crazy and
       | should never be done. But from a broader perspective it's clearly
       | very beneficial for the advancement of science to have such
       | fearless pioneers. Amazing stuff!
        
       | mertleee wrote:
       | I'm not religious, but publishing this the day before Easter is
       | disgusting.
        
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