[HN Gopher] New nanoparticle therapies target two major killers
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New nanoparticle therapies target two major killers
Author : rbanffy
Score : 84 points
Date : 2025-03-31 14:18 UTC (4 days ago)
(HTM) web link (www.science.org)
(TXT) w3m dump (www.science.org)
| pwdiscflatmajor wrote:
| Science and AAAS are killers?
| throwawa14223 wrote:
| That's how I read the headline at first.
| ceejayoz wrote:
| I suppose we'll have to hope researchers overseas complete the
| work.
|
| https://arstechnica.com/health/2025/03/federal-funding-for-m...
|
| > Federal support for mRNA vaccine research appears in jeopardy
| after KFF Health News reported Sunday that officials at the
| National Institutes of Health have directed scientists to remove
| all references to the lifesaving technology from their grant
| applications. All such research is now under direct scrutiny from
| health secretary and long-time anti-vaccine advocate Robert F.
| Kennedy Jr.
| nimbius wrote:
| Chinese scientists under the steadfast leadership of the
| communist party of China will gladly undertake this important
| scientific research.
| rbanffy wrote:
| There is a point to be made in favor of political stability.
|
| One of the great things in Ireland is the list-based voting
| that punishes extreme viewpoints and policies. OTOH,
| sometimes we need politicians willing to make unpopular
| choices, and our system makes that more difficult.
|
| China, IIRC, has a different concept, one where a person
| can't be a candidate to a position more than one level higher
| than the highest one they were previously elected for. This
| prevents anomalies like Trump, and seems to be a very
| sensible approach (if coupled with a couple extra freedoms
| and multiple parties).
| wkat4242 wrote:
| Xi Jinping has removed many of those protections though
| like the maximum term count so he could stay in power.
|
| And Ireland politics got me pretty sad. It just seems to
| pingpong between two equally inept parties (fianna fail and
| fine gael) and nothing new ever happens. They just keep
| piling problem on problem without ever solving anything. I
| remember there being a lot of fuss about patients in
| hallways during mary harney's reign in the mid '00s and I
| don't think that was ever solved. Last time I ended up in
| hospital there I ended up in exactly that situation. The
| post-2007 housing crisis is another one. Does anyone
| actually expect that to be ever solved? And the strange
| thing is, this country has no shortage of land whatsoever.
|
| What happens is that one party blames their predecessor and
| wins the election and then next term things switch back
| again through exactly the same mechanism.
|
| I think something more left like sinn fein would be good
| for the country but they have too much image baggage due to
| their past. And labour seems to really just sit at the
| sidelines forever.
| TechDebtDevin wrote:
| >What happens is that one party blames their predecessor
| and wins the election and then next term things switch
| back again through exactly the same mechanism.
|
| This is literally the United States for the last half
| century.
| colechristensen wrote:
| The unpopular choices that need to be made in America are
| the centrist ones.
|
| One of them being "whether it's left- or right-aligned,
| let's not engage in your social agenda on the federal level
| for a while"
|
| >where a person can't be a candidate to a position more
| than one level higher than the highest one they were
| previously elected for
|
| For much of the time in the Roman Republic they also had
| this
|
| https://en.wikipedia.org/wiki/Cursus_honorum
| jimbob45 wrote:
| So you have to work your way up from the bottom? Surely
| there's a mathematical impossibility to get to the
| presidency here unless you're making astronomical progress
| year over year?
| ceejayoz wrote:
| There aren't _that_ many (11) levels.
|
| https://en.wikipedia.org/wiki/Civil_service_of_the_People
| %27...
|
| Functionally, the US _mostly_ works the same way - people
| start in small local roles and move to county, state, and
| national levels over time. It 's just not enforced as a
| hard rule, just a practical thing.
| jimbob45 wrote:
| That makes more sense then. The US probably has around
| that number too and you're right that we do mostly work
| up from the bottom. The most common method of avoiding
| the ladder is through military service but that's
| basically a parallel ladder requiring very similar work.
| ceejayoz wrote:
| Yeah. If you're a somewhat senior officer in the
| military, you know how to do things like budget, manage,
| lead, etc. that all come in handy running an organization
| like a campaign or Congressional office.
| ajuc wrote:
| The only 2 countries on Earth - USA and China.
|
| You don't have to choose between oligarchy and communism.
| There's normal countries out there.
| slowmovintarget wrote:
| Some more words from Aristotle to aid the discussion:
| https://www.worldatlas.com/articles/the-different-forms-
| of-g...
|
| I'd probably go with plutocracy for the U.S., but we're in
| the process of trying to disrupt that. (Trying...)
| TechDebtDevin wrote:
| Yes, lets go back to how it was in the 20s and 30s in the
| United Sates... Said noone ever. I wish I had a time
| machine for these people.
| FuriouslyAdrift wrote:
| I'm a huge fan of how Switzerland does it. We USED to be
| that pre-Great Depression / New Deal.
| moffkalast wrote:
| _in mice_
| fnord77 wrote:
| so how long until clinical deployment?
| bookofjoe wrote:
| I don't know if I did the right thing when I stopped posting
| research articles here involving mice rather than humans. All I
| know is that I got tired of always seeing
|
| >in mice
|
| as the top comment.
| tqi wrote:
| (I have not taken a biology class since high school so please
| bear with me if this is a stupid question)
|
| For this treatment to work in people, does the targeting peptide
| have to be tailored specifically for the individual receiving the
| treatment, or is mostly universal?
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(page generated 2025-04-04 23:02 UTC)