[HN Gopher] Asteroid fragments upend theory of how life on Earth...
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       Asteroid fragments upend theory of how life on Earth bloomed
        
       Author : bookofjoe
       Score  : 93 points
       Date   : 2025-03-01 12:44 UTC (4 days ago)
        
 (HTM) web link (www.nature.com)
 (TXT) w3m dump (www.nature.com)
        
       | bookofjoe wrote:
       | https://archive.is/Zw2gh
        
       | disqard wrote:
       | > Not only does Bennu contain all 5 of the nucleobases that form
       | DNA and RNA on Earth and 14 of the 20 amino acids found in known
       | proteins, the asteroid's amino acids hold a surprise.
       | 
       | > On Earth, amino acids in living organisms predominantly have a
       | 'left-handed' chemical structure. Bennu, however, contains nearly
       | equal amounts of these structures and their 'right-handed',
       | mirror-image forms, calling into question scientists' hypothesis
       | that asteroids similar to this one might have seeded life on
       | Earth.
        
         | twothreeone wrote:
         | Hm, why would chirality need to be a consequence of the
         | panspermia hypothesis? I thought the mission defined "necessary
         | ingredients for life" as any bio markers that might have seeded
         | a primordial soup on Earth.
        
           | tomohelix wrote:
           | One way to interpret the results here is that all the
           | building blocks of life can naturally be formed right here on
           | earth or anywhere that has conditions similar to where Bennu
           | came from.
           | 
           | The fact that the components on the asteroid is racemic meant
           | or heavily suggested that they were formed using non-biogenic
           | means. And if so, it also means that Earth could have had the
           | same thing happened a long time ago, leading to the seeds of
           | life.
           | 
           | tl,dr: this discovery weaken the panspermia hypothesis.
        
           | lupusreal wrote:
           | Abiogenic synthesis of "primordial soup" is fairly straight
           | forward, see the Miller-Urey Experiment. A soup of random
           | amino acids and whatnot might be created in a number of ways
           | on Earth, so it's a stretch and not very interesting to
           | suppose that such soups didn't exist on Earth and were
           | brought in by space. The interesting panspermia hypothesis is
           | that actual life came down from space. Finding amino acids in
           | space could be evidence for that, but if the stuff found in
           | space is mixed chirality that undermines those chemicals as
           | evidence of life in space. Mixed chirality implies a mundane
           | abiogenic origin.
        
             | wjnc wrote:
             | Couldn't there exist a chirality filter on earth?
        
               | XorNot wrote:
               | The question is "how?" though. The chirality filter on
               | Earth is basically Earth-life: it almost ubiquitously
               | creates left-handed amino acids. But all known chemical
               | ways of doing this produce racemic mixtures of both
               | types.
               | 
               | If we found say, a high pressure synthesis method which
               | was heavily biased chirally, then that would be good
               | evidence but none has been discovered.
        
               | nkrisc wrote:
               | Is there any evidence of one or such a theory?
        
               | wjnc wrote:
               | I am a total noob in chemistry and Claude said that it
               | was a great question, but the answer were quite unclear
               | about the feasibility. Mainly theoretical filters on lab
               | scale. So that led me to put forward the thought.
        
               | jerf wrote:
               | Nobody has found or even so much as proposed a very good
               | one. There's a bare handful of reactions that can tend to
               | amplify chirality, but most uncontrolled chemistry
               | (including things like Miller-Urey) produce a
               | biologically-useless random high-entropy mix, and it is
               | fairly unclear that these handful of reactions, which
               | aren't even necessarily obviously useful ones and require
               | some fairly special conditions, could possibly overwhelm
               | the entropy of all the other reactions blasting out
               | random combinations of things.
               | 
               | AFAIK there isn't even a known way to start with "normal
               | chemicals" and produce highly-chiral reactions reliably
               | in the lab. We get all our chiral molecules by extracting
               | them from biology.
        
             | miramba wrote:
             | These findings show that biochemical compounds, once
             | thought to be fragile and denaturate quickly in non-earth
             | conditions, can apparently survive space conditions for a
             | long time, even in universe metrics, so they could travel
             | far. If they can, maybe cells can too. But that doesn't
             | mean it's likely to find actual life on a random asteroid.
             | Of course there is equal chirality in lifeless conditions.
             | The ultimate question is: How did the first cell came to
             | be? Everything after that seems explainable, if not
             | predetermined. But that the first cell just randomly
             | happened in the primordial soup - that looks extremely
             | unlikely, yet it's the best explanation so far. If cells
             | could travel on asteroids, it's (equally? Less? Who could
             | tell?) likely that the first cell just dropped here,
             | intentionally or otherwise. Which would put the question of
             | creation just to a different time and place. Somewhere in
             | the universe, billions of years ago, life happened. Maybe
             | it spread through the galaxy. Maybe sometimes a life
             | carrying planet explodes, spreading asteroids with cells.
             | Maybe some of them drop on planets with the right
             | conditions. Given enough time, how unlikely is that as
             | compared to random creation here?
        
           | dguest wrote:
           | There's a weak connection, but to me it reads like clever
           | marketing.
           | 
           | Actually _finding_ chirality in space would be extremely cool
           | in that it would mean one of two things:
           | 
           | - the panspermia hypothisis is correct, or
           | 
           | - some non-biological process creates chiral molecules.
           | 
           | Physics itself has plenty of chiral processes, but they only
           | show up in the weak interaction. As the name implies, the
           | weak interaction is really really weak and essentially
           | doesn't exist on the energy scales of molecular interactions.
           | So chirality would be a bit of a smoking gun for panspermia.
           | 
           | On the other hand, _not_ finding chirality just means we don
           | 't have a smoking gun. There might be another asteroid flying
           | around that is 100% chiral, or maybe 50% of them and we were
           | just unlucky.
           | 
           | The briefing joins the point about chirality with evidence
           | against panspermia, but really that might miss the point.
           | Chiral or not, abundant amino acids in space means that one
           | of the many steps to create life is relatively simple. If we
           | could show that every subsequent step is simple that would be
           | a big blow against panspermia. But in that case ruling out
           | panspermia would be pretty cool, since it would suggest that
           | life exists everywhere.
        
             | close04 wrote:
             | > the panspermia hypothisis is correct
             | 
             | What I don't understand is why would chirality and
             | panspermia be so tightly linked.
             | 
             | The data right now still leaves every option on the table
             | just because having any ratio of chiral molecules doesn't
             | _have_ to define how _life_ evolves. It can 't answer
             | whether those molecules formed on Earth or hitched a ride
             | on an asteroid, or life itself formed here or was brought
             | here.
             | 
             | We can assume that in a soup with balanced proportions of
             | each chirality, the left handed molecules created a self
             | replicating mechanism (some definition of "life") first or
             | faster than right handed molecules, either accidentally or
             | because some yet undiscovered advantage. Whether this
             | happened on Earth, or was brought to Earth by one or more
             | of the millions of asteroids is hard to prove.
        
               | dguest wrote:
               | That's a good point. You also need consistency in the
               | chirality on asteroids (also with earth).
               | 
               | If we find one asteroid with chirality that _doesn 't_
               | match earth, it's good evidence that self replication
               | just happens spontaneously rather than being seeded.
               | 
               | If we find only one asteroid with one chiral molicule
               | that _does_ match earth, that supports panspermia very
               | weakly: it still might just be random chance. But
               | multiple matching molecules, on multiple asteroids,
               | starts to seem like evidence for a common source.
               | 
               | On the other hand: If we find multiple molecules with
               | matching chirality, on multiple asteroids, and _none of
               | them match with earth_... well, we should probably start
               | preparing for the invasion.
        
             | marcosdumay wrote:
             | > There might be another asteroid flying around that is
             | 100% chiral, or maybe 50% of them and we were just unlucky.
             | 
             | The more asteroids we look and not find any asymmetry, the
             | more evidence we have that life never existed on any of
             | them.
        
           | roxolotl wrote:
           | I don't know a ton about how chirality works. Couldn't it
           | just be that half(or some number) the asteroids contain left
           | handed and half contain right? We only have a sample of one.
           | Or is there something fundamental about left handed molecules
           | that gives us reason to believe that if we see right handed
           | ones once we would rarely see left handed ones in similar
           | disconnected systems?
        
             | jcranmer wrote:
             | Chirality means that there is a mirror image of a molecule
             | that cannot be twisted into the original shape, despite
             | being structurally identical. Due to the particular ways
             | molecules tickle each other in living organisms to do
             | interesting things, that means that the mirror image
             | (racemate) of a molecule does something different.
             | 
             | In chemical synthesis, most (but not all) processes tend to
             | preserve chirality of molecules: replacing a bunch of atoms
             | in a molecule with another set will tend to not cause the
             | molecule to flip to a mirror image. If you start from an
             | achiral molecule (one where its mirror image can be rotated
             | to the original), almost all processes tend to end up with
             | a 50-50 mix of the two racemates of the product.
             | 
             | In biochemistry, you can derive all of the amino acids and
             | sugars from a single chiral molecule: glyceral. It turns
             | out that nearly all amino acids end up in the form derived
             | from L-glyceral and nearly all sugars come from D-glyceral.
             | The question of why this is the case is the question of
             | homochirality.
             | 
             | There's as yet no full answer to the question of
             | homochirality. We do know that a slight excess in one
             | racemate tends to amplify into a situation where only that
             | racemate occurs. But we don't know if the breakdown into
             | L-amino acids and D-sugars (as opposed to D-amino acids and
             | L-sugars) happened by pure chance or if there is some
             | specific reason that L-amino acids/D-sugars is preferred.
        
               | westurner wrote:
               | "I Applied Wavelet Transforms to AI and Found Hidden
               | Structure" https://news.ycombinator.com/item?id=42956262
               | re: CODES, chirality, and chiral molecules whose
               | chirality results in locomotion
               | 
               | Do any of these affect the fields that would have
               | selected for molecules on Earth? The Sun's rotation,
               | Earth's rotation, the direction of revolution in our by
               | now almost coplanar solar system, Galactic rotation
        
               | roxolotl wrote:
               | That's definitively helpful thank you. I guess I'm still
               | surprised that this finding is being taken to mean left
               | handed molecules couldn't have come from asteroids. If
               | anything it seems to me to increase the likelihood of the
               | panspermia hypothesis.
        
               | jcranmer wrote:
               | The reason this makes panspermia less likely is that the
               | panspermia hypothesis would prefer to put the point at
               | which all amino acids become L-amino acids before arrival
               | on Earth, whereas the evidence is that the amino acids on
               | this asteroid is before that point.
        
               | roxolotl wrote:
               | That makes sense. I'm just thinking statistically though.
               | All we've proven is that some asteroids have R-amino
               | acids. If it's a 50/50 shot you could easily find a dozen
               | R asteroids because it starts to look really bad for it
               | being a 50/50 split.
               | 
               | I guess the reason it makes things more likely is because
               | homochirality happens so aggressively that finding right
               | handed molecules at all drastically reduces the odds of
               | left.
        
               | divbzero wrote:
               | This is a good explanation of chirality but I think the
               | parent meant to say _enantiomer_ instead of _racemate_ :
               | 
               | - _enantiomer_ refers to each mirror image of the
               | molecule. https://en.wikipedia.org/wiki/Enantiomer
               | 
               | - _racemate_ refers to a 50-50 mix of the two
               | enantiomers.
               | https://en.wikipedia.org/wiki/Racemic_mixture
        
         | madaxe_again wrote:
         | I don't quite see how it disproves or undermines panspermia -
         | surely if earth began with a racemic mixture of the building
         | blocks, life could have started with either chirality (both
         | being an unlikely scenario what with it vastly increasing
         | complexity and therefore decreasing probability of evolution),
         | and would then select for that chirality exclusively - so it's
         | no great surprise we have ended up with a single-handed
         | biosphere.
        
           | throwanem wrote:
           | An explanation is required for why that selection occurred
           | here, and not in whatever biosphere from which this one was
           | panspermically inseminated.
        
         | bloomingkales wrote:
         | I wonder how much deep sea research we'd have to do to find all
         | the possible impact craters. There's gotta be lot of evidence
         | at the source.
        
       | metalman wrote:
       | given the very deep time that these fragments have existed, It
       | would be best to exhaust all possible or almost impossible ways
       | that perhaps left handed enantomers could convert to right handed
       | becuase 1 in a billion chances round up to every time....
        
         | japaget wrote:
         | The term for this process is "racemization".
        
       | datadeft wrote:
       | The evolution theory of origin of life just got a kick in the
       | wrong spot?
       | 
       | It is kind of weird how defensive is that crew. It is very much
       | possible that life on Earth has extraterrestrial origins. I do
       | not see why somebody would try to discard this idea.
        
         | JohnMakin wrote:
         | Uh, no? And I think you're confusing abiogenesis with the
         | process of evolution - they are different processes.
        
         | krapp wrote:
         | I don't think you understand what "very much possible" means.
         | It isn't a synonym for "I very much believe."
         | 
         | We have actual evidence of evolution as a real and active
         | process and can (and have) studied and mapped that process
         | across species and across time - including in humans - and we
         | find absolutely no evidence of nor the necessity for
         | extraterrestrial influence anywhere.
         | 
         | And even if some flavor of is assumed true for the sake of
         | argument, that still wouldn't somehow negate evolution. It's
         | entirely possible for life to have an extraterrestrial origin
         | _and to have evolved_ on Earth after that origin, having first
         | _evolved_ somewhere else.
        
           | datadeft wrote:
           | I am not saying it would negate evolution. I am saying
           | origins of life could be extraterrestial and then life goes
           | on a evolutionary process.
        
             | literalAardvark wrote:
             | This finding invalidates the idea that Bennu was seeded
             | with molecules by biological life: biological life would
             | have created chiral molecules, but the mix on Bennu is
             | racemic, which suggests that the molecules were created by
             | run of the mill geological processes and simply wouldn't
             | require extraterrestrial seeding.
             | 
             | Tldr the finding is that abiogenesis may be easier to get
             | to than previously thought.
        
               | pfdietz wrote:
               | > Tldr the finding is that abiogenesis may be easier to
               | get to than previously thought.
               | 
               | It doesn't really mean that, though. We already knew
               | synthesis of simple amino acids was pretty easy. Urey-
               | Miller did that decades ago. Making the easy part of a
               | multistep process easier doesn't make the whole process
               | much easier.
               | 
               | IMO, the rate-limiting step for OoL is later, when by
               | some means the enormous complexity barrier is reached
               | between abiotic stuff like this and the simplest self-
               | replicating system capable of evolution. Of the latter,
               | the simplest we know (the most stripped down cell) still
               | contains billions of atoms.
        
         | drbojingle wrote:
         | Evolution is a description of what we see happening in animals
         | over time. That's all. This is about the formation of life.
        
           | datadeft wrote:
           | "Historically, ideas on the origins of life have been mingled
           | with evolutionary explanations. Darwin avoided discussing the
           | origin of the very first species in public although he
           | acknowledged the possibility that life originated by natural
           | causes. Some of his followers adopted this materialistic
           | position and advocated some sort of spontaneous generation in
           | the distant past. Nevertheless, Pasteur's experiments were a
           | major obstacle for scientific acceptance of the sudden
           | emergence of life. The scientific study of the origin of
           | life, established in the 1920s, required abandoning the idea
           | of a unique chance event and considering a view of life
           | emerging as the result of a long evolutionary process."
           | 
           | https://evolution-
           | outreach.biomedcentral.com/articles/10.100...
        
             | drbojingle wrote:
             | That's nice but there's still no reason to talk about
             | things that reproduce and the origins of the building
             | blocks of things that reproduce using the same word. Might
             | as well say both the grocery store and the celery you
             | bought are both stew. Or that shopping is cooking.
        
             | User23 wrote:
             | I think "how did non-living matter become alive" and "how
             | do populations of organisms change over time" are two very
             | different questions.
        
         | 8bitsrule wrote:
         | I wouldn't discard the idea, but OTOH, life -had to happen
         | somewhere first-. That first clearly happened, and without
         | extraterrestrial seeding. So that life either evolved, or ...
         | because of the chemical makeup of the universe ... life is
         | inevitable given the necessary conditions. This latter is a
         | simpler and sufficient model.
        
       | MarkMarine wrote:
       | https://archive.is/3Wf9d
        
         | observationist wrote:
         | This is just a capture of the paywall, fyi.
        
       | pfdietz wrote:
       | This is interesting because the very earliest asteroids were
       | warmed by short-lived radioactive decay. So, even small ones
       | could have had interiors with liquid water. Their combined volume
       | would have been very large, making them all potential sites for
       | origin of life. Subsequently, impacts could have led to seeding
       | of this life on the inner planets, including Earth and Mars.
       | 
       | If these truly were the sites of OoL in our solar system, then
       | that means life either originated early, before these asteroids
       | froze up or dried out, or it wouldn't arise at all. This would
       | vitiate the argument that because life appeared early on Earth,
       | OoL must occur with high probability.
        
       | zkmon wrote:
       | Darwinism explains how the biological transformations and
       | adaptations lead to racial diversity. However, the very goal
       | which drives the adaptation, growth, reproduction or replication
       | etc is not clearly explained, in my view. Questions like, why
       | should the creatures have a root goal of growth and reproduction,
       | why should a cell divide etc might need more thought. Was there a
       | cognitive intention behind this adaptation? How did that
       | intention originate and evolve? If the intention originated from
       | inorganic material, does it still happen?
        
         | bandushrew wrote:
         | The why explains itself. Cells that do not divide and reproduce
         | disappear.
        
         | jhrmnn wrote:
         | There are no goals in evolution. The most fit strain reproduces
         | faster, eventually dominating other less fit strains. There's
         | no purpose, it just happens.
        
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