[HN Gopher] Medical treatments devised for war can quickly be im...
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       Medical treatments devised for war can quickly be implemented in US
       hospitals
        
       Author : PaulHoule
       Score  : 26 points
       Date   : 2025-02-28 16:18 UTC (6 hours ago)
        
 (HTM) web link (theconversation.com)
 (TXT) w3m dump (theconversation.com)
        
       | westurner wrote:
       | > _Our research, and that of others, found that too much oxygen
       | can actually be harmful. Excess oxygen triggers oxidative stress
       | - an overload of unstable molecules called free radicals that can
       | damage healthy cells. That can lead to more inflammation, slower
       | healing and even organ failure._
       | 
       | > _In short, while oxygen is essential, more isn't always
       | better._ [...]
       | 
       | > _We discovered that severely injured patients often require
       | less oxygen than previously believed. In fact, little or no
       | supplemental oxygen is needed to safely care for 95% of these
       | patients_
       | 
       | Oxidative stress: https://en.wikipedia.org/wiki/Oxidative_stress
       | 
       | Antioxidant > Levels in food:
       | https://en.wikipedia.org/wiki/Antioxidant#Levels_in_food
       | 
       | Anthocyanin antioxidants:
       | https://www.google.com/search?q=anthocyanin+antioxidants
        
         | westurner wrote:
         | Deep sea divers know about oxygen toxicity;
         | 
         | Trimix (breathing gas)
         | https://en.wikipedia.org/wiki/Trimix_(breathing_gas) :
         | 
         | > _With a mixture of three gases it is possible to create mixes
         | suitable for different depths or purposes by adjusting the
         | proportions of each gas. Oxygen content can be optimised for
         | the depth to limit the risk of toxicity, and the inert
         | component balanced between nitrogen (which is cheap but
         | narcotic) and helium (which is not narcotic and reduces work of
         | breathing, but is more expensive and can increase heat loss)._
         | 
         | > _The mixture of helium and oxygen with a 0% nitrogen content
         | is generally known as heliox. This is frequently used as a
         | breathing gas in deep commercial diving operations, where it is
         | often recycled to save the expensive helium component. Analysis
         | of two-component gases is much simpler than three-component
         | gases._
        
         | westurner wrote:
         | HFNC (High-Flow Nasal Cannula) breathing tube therapy is
         | recommended by various medical guidelines.
         | 
         | HFNC and prone positioning is one treatment protocol for COVID
         | and ARDS Acute Respiratory Distress Syndrome: you put them on
         | their stomach and give them a breathing tube (instead of a
         | ventilator on their backs).
         | 
         | Which treatment protocols and guidelines should be updated
         | given these findings?
         | 
         | For which conditions is HFNC therapy advisable given these
         | findings?
         | 
         | Heated humidified high-flow therapy:
         | https://en.wikipedia.org/wiki/Heated_humidified_high-flow_th...
        
       | acc_297 wrote:
       | >To build on our findings, we've launched a trial to study the
       | use of artificial intelligence to automate oxygen delivery.
       | 
       | Not to beat a dead horse but looking over what I believe is the
       | patent [1] for the oxygen delivery device in question this seems
       | to be another case of a standard industrial control algorithm
       | being dressed up as "AI"
       | 
       | [1] https://patents.google.com/patent/EP3996787B1/en
        
         | Etheryte wrote:
         | Adding to that, I struggle to think of many things more
         | terrifying than relying on contemporary AI for oxygen delivery.
        
       | 42lux wrote:
       | Nothing can get quickly implemented in the medical field.
        
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       (page generated 2025-02-28 23:02 UTC)