[HN Gopher] Migraine is more than a headache - a rethink offers ...
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       Migraine is more than a headache - a rethink offers hope
        
       Author : rntn
       Score  : 243 points
       Date   : 2025-02-18 15:47 UTC (1 days ago)
        
 (HTM) web link (www.nature.com)
 (TXT) w3m dump (www.nature.com)
        
       | markx2 wrote:
       | I was around 13 when I had my first migraine. A solid block of
       | pain on the right side of my head. That occasional migraine
       | became more frequent over the years. I had a headache 24/7 in one
       | specific place in my head.
       | 
       | In my early 30's, after blood tests, food elimination, x-rays and
       | finally an MRI I was told that I had Chronic Daily Migraines.
       | 
       | Most days were 6-7/10 pain. Those days that were 10/10 I
       | perfected the art of lying down and breathing in such a way that
       | I barely moved. Noise / light were never an issue, the pain got
       | worse when I moved.
       | 
       | Then I got a daith piercing.
       | 
       | I had read that a daith could help.
       | 
       | I got the daith ~14 years ago and I have not had any sort of
       | headache since. Both my daughters who had migraines got a daith
       | and they too have no headaches.
       | 
       | I get the sample size is not useful, but if you have migraines,
       | go into your local proper piercing studio and ask for a daith -
       | they will almost certainly reply "On which side of your head is
       | the pain?"
        
         | canadiantim wrote:
         | fascinating, thanks for sharing
        
         | ToDougie wrote:
         | truly fascinating comment..... will have to research this
         | further!
        
         | isoprophlex wrote:
         | If this is because of the piercing doig some vagus nerve
         | stimulation, do you think a simple, small clip or something
         | placed in the right position could help as well?
        
           | markx2 wrote:
           | That I do not know.
           | 
           | It's worth trying but the positioning would be tricky.
           | 
           | All I know is as I have posted - the daith piercing stopped
           | the pain.
        
             | isoprophlex wrote:
             | Thanks anyway, I'm definitely looking into this.
             | 
             | Suffering from the occasional migraine myself (3-4x year)
             | it seems a bit too drastic for myself... but my wife has
             | very frequent migraines, anything that could possibly help
             | is worth investigating
        
               | markx2 wrote:
               | I got a new puppy - Dogue de Bordeaux - some months ago
               | and she was/is on a raw food diet, so I had to get that
               | delivered frozen.
               | 
               | Couple of deliveries in and I got chatting to the guy
               | bringing the food. He mentioned he had headaches
               | constantly. I told him about the daith.
               | 
               | Days later he messaged me - he'd got a daith after we
               | talked and today, for the first time in 10+ years he woke
               | in no pain, no need to take codeine.
               | 
               | Just go to a proper piercing place, not some "Claire's"
               | type place.
        
               | spondylosaurus wrote:
               | Try https://safepiercing.org/ !
        
         | orthecreedence wrote:
         | I've heard of this piercing so many times and always wrote it
         | off as some mass hypnosis quick fix that would change nothing.
         | Your comment made me reopen that box I closed years ago. I'm
         | very curious now.
         | 
         | Did you get the piercing on your left or right ear?
        
           | markx2 wrote:
           | Right ear because the pain was on the right side of my head.
        
         | jmhammond wrote:
         | I'm willing to try it! Are you able to wear earbuds with the
         | daith piercing? Airpods Pro are one of my most-used pieces of
         | tech both at work live-streaming classes and at home listening
         | to books and music.
        
           | markx2 wrote:
           | Yes!
           | 
           | I have worn various and my current are Airpods 2 Pro.
           | 
           | The daith is discreet, does not get in the way of anything.
        
             | seattle_spring wrote:
             | What about wearing a winter hat? I was considering getting
             | one for the exact reasons as you, but I live in a pretty
             | cold area and not being able to wear a hat for 6 months
             | during its healing process is unfortunately a dealbreaker.
        
               | markx2 wrote:
               | Unless the hat has a hard edge which sits right on top of
               | the piercing you should be fine.
        
         | whutsurnaym wrote:
         | Throwing in my anecdata:
         | 
         | I had migraines at least once every two weeks for most of my
         | life. Nothing too out of the ordinary, just that 7/10 dull pain
         | in the center of my head that shut me down for 5 or 6 hours.
         | 
         | I'm very skeptical about supposed instant fixes like this. I
         | didn't expect it to work, but I wanted to start getting ear
         | piercings and I figured I'd give it a shot with something not
         | too flashy. I went with my wife to her piercing appointment and
         | convinced them to pierce my left daith while we were already
         | there.
         | 
         | That was at least seven years ago. I haven't had a migraine
         | since. I keep assuming it's placebo and it'll wear off, but it
         | hasn't.
        
         | LeoPanthera wrote:
         | Research says it's no more effective than a placebo, but hey,
         | if it works, it works.
         | 
         | https://headachejournal.onlinelibrary.wiley.com/doi/10.1111/...
        
           | dumbfounder wrote:
           | I have tried vagus nerve stimulation and it worked for about
           | a week and then became mostly ineffective. That is consistent
           | with this study. So, maybe try vagus nerve stimulation first
           | and see if that works long term.
        
           | willy_k wrote:
           | > Research says it's no more effective than a placebo, but
           | hey, if it works, it works.
           | 
           | The paper you cited doesn't say this, if anything it says the
           | opposite. It found that it reliably works for some amount of
           | time, but the mechanism is unclear.
           | 
           | "In all case studies and the retrospective study, patients
           | reported substantial reductions in pain immediately after
           | daith piercing; however, headache symptoms recurred several
           | weeks to months thereafter. From the perspective of the
           | Chinese and Western auricular systems, no sufficient
           | explanation for the described treatment effect of daith
           | piercing was found."
        
             | stuckonempty wrote:
             | A piercing that takes months to heal and has its own
             | potential side effects (infection for one) does not seem
             | worth weeks of relief after which pain returns. The authors
             | of this study therefore do not recommend this piercing for
             | migraines despite the transitory benefits
             | 
             | "current evidence does not support daith piercing for the
             | treatment of migraine, tension-type headaches, or other
             | headache disorders."
        
               | willy_k wrote:
               | That's very different from being equivalent to placebo.
               | And according to anecdotes in this thread, it may be
               | permanent in some cases.
        
       | aszantu wrote:
       | I seem to get migraines from plant fats and stimulants like
       | caffeine.also caffeine withdrawal.Been drinking chaga coffee a
       | few days and feel so much better in the evening
        
       | greenavocado wrote:
       | Magnesium L-Threonate changed my life. I no longer experience
       | headaches daily.
        
         | entangledqubit wrote:
         | If this ever stops working for you, try one of the magnesium
         | mixes like MagTech.
        
         | cenazoic wrote:
         | Yes! I'm a 50+ woman diagnosed as a teenager, and daily
         | magnesium changed my life. I rarely get a migraine these days,
         | and I'm glad to hear it's effective for others.
        
       | wozer wrote:
       | > Migraine can even drive full-blown visual hallucinations
       | similar to the 'reflections of the living light' painted by
       | Hildegard von Bingen, a twelfth-century abbess who was thought to
       | have experienced a condition that is now called migraine with
       | aura.
       | 
       | I don't think the aura effects are usually considered
       | hallucinations?
       | 
       | I get mild migraines sometimes, with hardly noticeable headache,
       | but with aura. In a way, it's pretty cool. You can directly
       | perceive the abnormal brain activity and how it develops in real
       | time. (I get the classic zigzag lines wandering across the field
       | of vision.)
        
         | readyplayernull wrote:
         | AI hype terminology? Should be a visual effect.
        
           | graypegg wrote:
           | Hallucination is a medical term.
           | https://en.wikipedia.org/wiki/Hallucination
           | 
           | The usage in relation to AI is a reference to the medical
           | term, not the other way around.
        
         | bootloop wrote:
         | I also have migraine with aura. There are visual effects but
         | also when I am looking into the mirror I can't see half of my
         | face and give this is a wrong perception of reality you might
         | consider it a hallucination?
        
           | constantlm wrote:
           | When I have aura it's always morbidly fascinating to me how a
           | part of my vision is not black, but it's just "missing"
        
             | orthecreedence wrote:
             | Same, the fortification aura is really kind of amazing,
             | putting aside the debilitating pain that's quickly
             | approaching. It's really weird to have a part of your
             | vision just "not there" as opposed to being black. It's
             | even stranger when looking at a face or some recognizable
             | object, and half of it disappears into nothingness while
             | the other half still exists. Fun to play with.
        
           | digitalsushi wrote:
           | the first time i had this, everyone's nose was missing. for
           | ten seconds it was funny and then i hid in a bathroom stall
           | at work, and texted my wife goodbye. i was positive i was
           | about to die. its really stressful to have bodies.
        
         | soupfordummies wrote:
         | my mom used to get these and said it was like "seeing dots"
         | 
         | anecdotally of course too, but is it more common for women?
         | I've only ever known 3-4 people that got these kinds of
         | migraines and they were all women.
        
           | isoprophlex wrote:
           | I sometimes but not always get an aura before a migraine.
           | 
           | Which was pretty fun the first time i got an aura, as i was
           | working in a chemistry lab. I described what was happening
           | (loss of vision, flashes of light, rapidly oscillating black
           | and white patterns) to this greybeard lab technician and
           | within 5 minutes the entire lab was evacuated, out of fear of
           | some weird chemical poisoning us all.
        
           | bootloop wrote:
           | Yes, its much more common for women, its rare for men.
        
           | doubled112 wrote:
           | I happen to be a man who gets migraines with aura, but I do
           | think they're more common in women. They started when I was
           | 14.
           | 
           | I get visual issues like tunnel vision and sparklies, but I
           | also get numbness in my face and extremities, confuse my
           | words (right parts of speech, not what I intend to say), and
           | often vomit.
           | 
           | Needless to say, the first one scared the crap out of my
           | mother and I.
           | 
           | I may or may not have a headache when this happens.
           | 
           | Neat, eh? I was talking to a guy who suffered from seizures
           | in college, and apparently his "aura" is very similar, and
           | I've always wondered if there was some connection since my
           | father also suffers from epilepsy.
        
             | tbirdny wrote:
             | Migraines and epilepsy have a lot in common, including some
             | symptoms and triggers. Drugs and things that lower seizure
             | threshold also tend to cause migraines. Some epilepsy drugs
             | also act as migraine prophylactics.
        
             | bpye wrote:
             | > I get visual issues like tunnel vision and sparklies, but
             | I also get numbness in my face and extremities, confuse my
             | words (right parts of speech, not what I intend to say),
             | and often vomit.
             | 
             | I've experienced migraines for years, but last year had my
             | first instance that messed with speech. It certainly
             | unsettled the friend I was with at the time.
        
           | valbaca wrote:
           | I'm male and I get visual auras with migraines (not often,
           | only once or twice a year). It's like a small area of old TV
           | static or (as I call them) "dead pixels" in my vision. It's
           | usually centered right in the middle of my vision, so reading
           | becomes impossible but I could do something else.
           | 
           | It usually spreads a little bit before dissipating. They can
           | happen with or before the actual migraine pain.
        
       | rconti wrote:
       | > "I used to think that disability travels with pain, and it's
       | only when the pain gets severe that people are impaired. That's
       | not only false, but we have treatments to do something about it,"
       | says Richard Lipton, a neurologist at the Albert Einstein College
       | of Medicine in New York City.
       | 
       | Am I the only one unable to grok this statement?
        
         | orthecreedence wrote:
         | He's saying that he used to just view the pain of migraines as
         | a disability, but now realizes that there are other components
         | to migraines besides pain that cause disability (such as brain
         | fog, emotional instability, blindness, etc)
        
           | rconti wrote:
           | Thank you, that makes more sense now; with that explanation I
           | can re-read the original quotes.
        
             | orthecreedence wrote:
             | I think "travels with" is an odd phrasing that distracts
             | from the meaning of the sentence. It took me a while to
             | parse as well.
        
               | rconti wrote:
               | Right- even though I was able to figure that bit out on
               | second or third reading, it threw me enough that the
               | second clause didn't truly make sense. Also, the subjects
               | of "That's not only false" and "to do something about it"
               | are _different_. So my train of thought kept derailing.
               | 
               | And this is for a native english speaker!
        
       | tiltowait wrote:
       | I think everyone who suffers migraines has their own
       | "relationship" with them.
       | 
       | Myself, I can tell when I am "pre-migraine" and know I have to
       | sit down for a bit lest one develops. They most often come from
       | eating junk food after exercise (I'm looking at you, Fritos). And
       | warming my hands often helps speed the recovery, though I always
       | end up with "tender brain" for 24-48h after.
       | 
       | I'm intrigued by another poster having success with Magnesium
       | L-Threonate and will be placing an order today. Even if I don't
       | have a migraine, I have a headache 8 days out of 10.
        
         | mh- wrote:
         | _> They most often come from eating junk food after exercise
         | (I'm looking at you, Fritos)._
         | 
         | Dehydration causes a good portion of mine, at least of the ones
         | that I can point to a proximate cause of. I wonder if that's
         | what you're experiencing, with the salty food after sweating?
        
       | tiahura wrote:
       | My eyes were opened a few years ago when I was reading my mom's
       | brain mri report. She had cancer and was undergoing radiation
       | treatment. The MRI noted lesions and said they could be due to
       | cancer/radiation OR MIGRAINES!
       | 
       | Holy moly! Migraines can cause brain damage!
        
         | bootloop wrote:
         | Anything backing this up except that one report? I haven't
         | heard of headaches or migraines causing permanent damage.
        
           | tiahura wrote:
           | Migraine Is Associated With Magnetic Resonance Imaging White
           | Matter Abnormalities https://jamanetwork.com/journals/jamaneu
           | rology/fullarticle/7...
           | 
           | "Research suggests that the answer is yes. Migraines can
           | cause lesions, which are areas of damage to the brain."
           | https://www.webmd.com/migraines-headaches/migraine-brain-
           | les...
        
             | dboreham wrote:
             | Some kind of local thermal overload?
        
           | spondylosaurus wrote:
           | Can confirm, I had a brain MRI in my early 20s and had a
           | number of white matter lesions that were supposedly caused by
           | migraines. No other cognitive or neurological issues. But I'm
           | due for another scan soon and hoping they haven't worsened :P
        
           | weddpros wrote:
           | Search Migrainous Infarction. I had one when I was 32 (53
           | now). It's very rare, but a migraine can cause a stroke (ie.
           | permanent brain damage), because of impaired blood flow. It
           | left me with a permanent scotoma ("black" hole in my fov,
           | visible from both eyes and with both eyes open).
           | 
           | I was scanning the comments to see if anyone needed that
           | information.
           | 
           | If the aura doesn't stop after an hour, better go to the
           | hospital (aura means reduced blood flow). Also NEVER take
           | triptans during an aura.
        
           | marsovo wrote:
           | Might be a question of cause and effect. My neurologist
           | theorized my migraines were triggered by microemboli leaking
           | through a PFO (leak between left and right side of the heart:
           | normally the lungs filter this stuff out)
           | 
           | PFO closed, migraines basically gone.
           | 
           | PFO can lead to stroke too for the same reason, and that's
           | when it's usually closed, after a stroke. Not all migraines
           | are caused by PFO. I went on blood thinners first for a year
           | as a test.
           | 
           | Here's the long story version:
           | https://news.ycombinator.com/item?id=40895116
        
       | bootloop wrote:
       | After checking on my migraine with aura by doing a MRI they found
       | a large AVM in my brain which could kill me any time.
       | 
       | So if you get the chance, take an brain MRI. You never know what
       | they might find.
        
       | orthecreedence wrote:
       | I've thought for a long time now that everyone has a migraine all
       | the time, but migraine sufferers temporarily lack the brain's
       | ability to ignore the ever-present pain.
       | 
       | In other words, the migraine isn't the addition of pain, but the
       | absense of a pain relief mechanism. I have no sources to back
       | this up, other than personal observation.
        
         | peterfirefly wrote:
         | That doesn't explain the auras.
         | 
         | https://en.wikipedia.org/wiki/Aura_(symptom)
        
           | bootloop wrote:
           | I got told that it could be indeed the case that my brain
           | continuously has small seizures but only from time to time
           | they break trough and cause the pain and auras which I would
           | then experience. They wanted to measure the brainwaves to
           | figure out if that was the case. That would also somehow fit
           | what OP said, so I guess this is known in the medical world
           | already. Or at least something in that direction.
        
             | elric wrote:
             | Only that's not how auras seem to work. The current
             | understanding is that they are caused by cortical spreading
             | depression - a slow travelling wave which depolarizes the
             | brain cells it passes through. These don't just happen
             | randomly in healthy controls.
        
           | groestl wrote:
           | Well, I think the Auras is my brain failing to filter out
           | visual noise, which then get's into a feedback loop and
           | builds up. And that might be related to other filter
           | functions failing. I think that, becaus4 once in a while, I'm
           | able to suppress the Aura conciously, when it is still very
           | small.
        
             | nextos wrote:
             | Some auras have a musculo-skeletal origin. For example,
             | some neck issue irritates a nerve or alters the pressure in
             | a blood vessel, which in turn affects the optic nerve.
             | 
             | I have suffered them myself, and they always came in a
             | sequence: arm pain, neck pain, headache and aura. Finally,
             | I'd release tension in my neck and it'd be gone.
             | 
             | My doctor confirmed injuries in cervical discs also seem to
             | be causally linked to auras, but there might be other
             | causes as well.
        
         | crazygringo wrote:
         | What personal observation makes you think everybody has a
         | migraine all the time?
        
           | orthecreedence wrote:
           | The pounding pain that corresponds with heartbeat. It makes
           | me think there are nerves that register this all the time but
           | there's some part of the nervous system that filters that
           | signal out.
        
             | crazygringo wrote:
             | I would suspect it is increased blood flow.
             | 
             | That's why you get a headache from caffeine withdrawal at
             | least, because the blood flow to your brain increases and
             | you then feel the pounding.
        
             | genewitch wrote:
             | Also tinnitus is said to always be present but the brain
             | can fail to filter it sometimes.
             | 
             | Like right now for me wtf
        
             | ianburrell wrote:
             | If you have pounding pain from heartbeat, you should go see
             | a doctor. That is not normal.
             | 
             | One feature of migraines is not just a headache. Some
             | people can feel it coming, called the aura. I feel weird
             | during and after the headache. I frequently get the
             | migraine weird feeling without the headache, so-called
             | silent migraine. Migraines and normal headaches feel
             | different.
        
       | iainctduncan wrote:
       | I have been a migraineur for decades. Mine are classic aura, with
       | the whole "looking through broken glass" thing for a half hour or
       | so when they happen. This year one of my partner's doctors
       | mentioned positive results from supplementing with Vitamin B-2
       | and Coenzyme Q10, and it has dramatcially lowered their
       | frequency. Mine are especially bad when the air pressure is
       | seesawing which it does a lot here in the spring and fall, but I
       | would guess I'm down to something like 20% of the previous years
       | numbers.
       | 
       | Definitely worth trying.
        
         | pan69 wrote:
         | > "looking through broken glass"
         | 
         | I think we have similar symptoms, but I have no headache, just
         | the "broken glass" that passes over my vision. Usually takes
         | about 15 mins to half an hour or so to pass.
         | 
         | This is the best visual representation that I have found of it
         | ove the years:
         | 
         | https://imgur.com/gallery/kY0I0Ht
        
           | bootloop wrote:
           | Yes that's silent migraine with aura, you experience the
           | visual effects but not the headache. It's rare but happens
           | for some people.
           | 
           | The representation is really good in my opinion! Gives me
           | flashbacks.
        
             | iainctduncan wrote:
             | I suppose an even better one would be "looking through
             | broken glass that keeps fucking moving around".
             | 
             | The weirdest thing I discovered was that, back when I
             | juggled professionally, I couldn't read at all during that
             | aura but could still juggle, even hard things like 5+
             | balls. Strangely it did not screw up peripheral vision.
             | 
             | Worst time was when it came on before a music school
             | performance. Not a hope in hell of keeping track of which
             | line the little circles were on...
        
           | alabastervlog wrote:
           | I used to get typical migraines, starting around junior year
           | of high school. One every 6-18 months, usually, for years.
           | Visual auras for twenty or thirty minutes, then a few hours
           | of bad headache.
           | 
           | Over the years the frequency has swung toward the longer end
           | of that, and now the last three times I haven't gotten the
           | headache part at all, but other weird symptoms. One time, bad
           | tunnel vision for a while and then feeling like I _had to_ go
           | to sleep immediately. Another, just a weird disconnected
           | /disembodied feeling for a couple hours. The most recent, I
           | got fairly bad aphasia for ten or fifteen minutes, which is
           | the fist time anything like that's happened to me. Not just
           | trouble thinking of words, though that too, but knowing the
           | word I wanted to say and having something else come out
           | instead, no matter how many times I tried.
           | 
           | Migraines are weird.
        
             | takomako wrote:
             | Have you tried a sumatriptan as soon as the aura starts?
             | Works for me. YMMV.
        
               | alabastervlog wrote:
               | I haven't tried anything but excedrine migraine. If I
               | still got a couple a year and they still gave me like 6
               | hours of killer headaches, I'd probably look into
               | something like that, but the frequency's been closer to
               | every other year than twice a year and I don't get much
               | pain with them now, so I've not bothered.
               | 
               | Maybe I should, though, given the other comments in this
               | thread about them causing brain lesions...
        
           | graypegg wrote:
           | The one aspect this misses that's so hard to communicate is
           | the lack of visual processing inside the sort of curled aura
           | "area". When I was getting them often as a kid, I would
           | basically become illiterate over the course of 15minutes,
           | because anything in that shimmering area was not parseable. I
           | could SEE the shape of a letter, but I couldn't read the
           | word. That shimmering area grows and grows till it's covering
           | all of your vision, but near the start you can still read out
           | of one side.
           | 
           | It was by far, the part of migraines I hated the most as a
           | kid because it took intense pain that people assume you're
           | overblowing, and prefaced it with 30-45 minutes of people
           | thinking I was an idiot/doing some weird awkward joke. (Or
           | having a stroke! The dread of not being able to speak
           | correctly, not being able to read, a slow pain in my temple
           | getting stronger and stronger, and now the teacher is calling
           | 911 while the class starts screaming.)
        
           | DontchaKnowit wrote:
           | Got this exact thing once last year a few months after
           | recovering from a very bizarre and severe viral infection
           | that ended with about 2 weeks of bells balsy.
           | 
           | It was bizarre. No headache at all. And unlike other posters
           | here, I could still read easily.
           | 
           | I think I had Parvo, no idea for sure tho
        
           | anonzzzies wrote:
           | Ah yes, that visual is perfect. I showed something similar to
           | a friend a long time ago and they said 'that's migraine? i
           | have that every few weeks but not much else so never thought
           | much of it; i thought migraines meant headaches'.
        
         | abrookewood wrote:
         | Just want to second this. I was getting migraines every 2 weeks
         | (visual auras, thumping headache for 3-6 hours etc) mainly
         | triggered by stress & lack of sleep as far as I could tell.
         | Started taking Vitamin B and I haven't had a migraine since -
         | for over a year).
         | 
         | There is research to back this up as well: -
         | https://pubmed.ncbi.nlm.nih.gov/33779525/ - Conclusion: Vitamin
         | B2 400 mg/day significantly reduced the duration, frequency,
         | and pain score of migraine attacks.
        
         | panta wrote:
         | There seems to be a link between migraines and Mithocondrial
         | Disease. If frequency/intensity of migraines diminishes with
         | Vitamin B and Q10, it may be worth investigating. Especially if
         | you have muscular fatigue or exhaustion.
        
         | elric wrote:
         | I've tried not CoQ10 and high doses of B2, without any impact
         | on my aura frequency or duration. Migraine auras are such a
         | pesky thing which medical science clearly doesn't understand.
         | The typical migraine drugs like triptans are useless for auras,
         | since the drugs typically take longer to kick in that the
         | duration of the aura.
         | 
         | Glad to hear the supplements are working. And you get to
         | impress peope with the colour of your pee!
        
       | tbirdny wrote:
       | First, I know different people have different triggers from me. I
       | used to have migraines every few days to every few months from
       | age 13 to 23. These would incapacitate me. I would get the aura
       | and be almost blind for an hour, then throw up a couple times,
       | and have a bad headache for 2-4 hours, then I could function
       | again but still felt crummy for the next 24 hours. I noticed that
       | pickles were a trigger, and I thought "pickles have a lot of
       | sodium". So, out of desperation as something to try, I read the
       | labels of everything I was eating and cut out everything that had
       | more than a little sodium: frozen pizza, frozen dinners, deli
       | meats, etc. At the time I was having migraines every few days,
       | and then I didn't have another migraine for years. I was so glad
       | they stopped. I now doubt it was the sodium. In cutting out
       | sodium, I happen to cut out processed foods, which includes lots
       | of suspicious ingredients. I suspect Tyramine was the main
       | culprit. There's a diet called The Headache Diet that is focused
       | on minimizing Tyramine. Guess what else pickles have a lot of?
       | For last last 30 years, here are all the things that have caused
       | my migraines: Lithium Carbonate (Orotate is OK), Pickled Herring
       | (Tyramine), Soy Sauce (Tyramine), Hyaluronic Acid (synthetic,
       | Mobilee is OK), Tianeptine, Sulbutiamine, and a strobe light.
       | Every migraine I have had in the last 30 years can be explained
       | by those - only 8-12 migraines total. I still precisely control
       | my sodium and eat no processed foods.
        
         | JKCalhoun wrote:
         | I too had nausea, auras with migraines when I was a teen. I
         | think I outgrew them. That or it was my girlfriend at the time
         | (I was about 20) that gave would snap my neck -- like some kind
         | of self-taught chiropractor.
        
       | cf100clunk wrote:
       | Any other migraineurs share what I call "Silver Bullet Fatigue"
       | at trying new treatments? I've been at this for six decades with
       | no magic solution for my own migraine problems, and I've lost
       | count of all the neurological investigations, meds, scans,
       | treatments, and helpful or sometimes utterly silly suggestions
       | that have come up short over the years. Some have come close but
       | had undesireable side effects, others made me very ill in their
       | own right. At this point I just don't have much desire to go
       | through the treatment wringer again. Am I alone in this sort of
       | fatigue?
        
         | munificent wrote:
         | Last spring, I broke my ankle severely (trimalleolar fracture
         | with dislocation). I had a very long string of complications
         | following that: fracture blisters, nerve block rebound pain,
         | opioid withdrawal, atrophy, infections, nerve pain, bone
         | fragments, etc. It seems that right when things seem to start
         | going well, a new complication arises.
         | 
         | I know it's not rational, but it's _really_ hard to not fall
         | into a mindset of  "Why even try to fix this one, another one's
         | going to happen anyway?" And once I start letting myself
         | believe that, I just feel even worse.
         | 
         | Even before this happened, I have had a pet theory that
         | _agency_ (and _perceived_ agency) is one of the most central
         | components of psychology around anxiety and depression. This
         | whole experience has reinforced it.
         | 
         | https://en.wikipedia.org/wiki/Learned_helplessness
        
           | cf100clunk wrote:
           | > I have had a pet theory that agency (and perceived agency)
           | is one of the most central components of psychology around
           | anxiety and depression
           | 
           | I like to think of that quality as being a person with a
           | willing desire to be a player on the team trying to solve the
           | health problem, in that I am generally a sunshine-y person
           | and try to see the best in things. To me, that's the key to
           | avoiding despair in facing my chronic, acute migraines.
           | Having said that, it is fatiguing to face batteries of tests
           | once again. If the science is very compelling, I'll consider
           | it.
        
         | geye1234 wrote:
         | CGRP blockers (specifically Nurtec) were practically a silver
         | bullet for me, but unfortunately not for everyone.
        
         | MR_Bulldops wrote:
         | Hey. I am not a migraine guy but a paroxysmal, full-body,
         | painful hives type of guy. Like some migraine people, my
         | symptoms eventually stopped happening after trying all sorts of
         | things for years, and I can't say precisely what the "cure"
         | really was. Or if I am not just in a 7-year-long remission.
         | 
         | Anyway, I experienced this fatigue you speak of. I am not sure
         | this will help you since your fatigue appears to come from
         | blood tests/medical treatments, but hopefully it helps
         | somebody. What helped was when the suggestion was something I
         | could do that was healthier/cheaper/more beneficial than what I
         | was currently doing, I would frame it as, "This might not fix
         | my debilitating problem, but it will improve my life in some
         | way. So, worst case scenario, I'm in the green."
         | 
         | Examples (I am not suggesting these as migraine silver bullets,
         | but I am trying to clarify what I mean):
         | 
         | - Someone in this thread mentioned cutting out xanthan gum and
         | other thickening agents has helped. Will that cure you?
         | Probably not. Is it a healthy lifestyle change? Probably. Why
         | not try?
         | 
         | - I cut out processed food, which helped me realize that I was
         | eating 1-3 frozen Trader Joe's meals per day. - I got an air
         | quality monitor that made me realize the brain fog I felt at
         | night was due to worsening air quality in my home. - I switched
         | to unscented soap and laundry detergent, which was cheaper.
         | (Artificial laundry scent now smells sickly and synthetic to
         | me, which may be a downside.) - I set up reminders for change-
         | by dates for furnace/car filters, vacuuming, dusting etc.
         | 
         | I don't know if any of this is why I don't experience symptoms
         | anymore, but I don't regret any of it, and have long-term
         | positive effects regardless.
         | 
         | Lastly, after several creams & allergy pills, I stopped getting
         | my hopes up that anything would fix me. Expectation management
         | is essential for avoiding fatigue.
         | 
         | Hope this helps you or somebody else. I am sorry you have
         | suffered for so long.
        
         | instagib wrote:
         | No. I read a migraine book which boiled down to once you figure
         | it out, your migraines change. Meds stop working, life changes,
         | stress, etc. I routinely get month long migraines over the
         | years. I've had all the scans, Mayo Clinic visits, eyes
         | checked, and follow-ups.
         | 
         | They say it's helpful to log things or journal but I don't feel
         | like it much with a migraine and blurred/double vision.
        
         | genewitch wrote:
         | I'm like this with back pain. I just reminisced the other day
         | about when I was a teen I could straddle on a brick wall and
         | pull with my arms to twist my torso around my hips and just pop
         | the f out of my lower back and hips, then I could stretch and
         | move normally again.
         | 
         | This worked for like 2 months. I've tried tiger balm, tens,
         | chiro, heat, cold, exercise, every medicine.
         | 
         | I have theracane, davinci back tool, and a long suffering wife
         | who will stand on my back to put enough pressure on the muscles
         | to help.
         | 
         | Tumeric, CBD. 7-hydroxymatiglynine nullifies the pain but I
         | puke 60% of the time I take it, about 4 hours later.
         | 
         | Mostly I just lay very still and whimper.
        
         | binary132 wrote:
         | For what it's worth, I got a sleep study and a CPAP machine due
         | to borderline hypertension, coincidentally also stopped taking
         | my migraine prevention medication, and I haven't had a single
         | migraine since, a year and a few months later. Maybe like half
         | of one, one time. Blood pressure is also back to normal.
         | 
         | In my case CGRP agonists made me feel absolutely horrible and
         | actually gave me long-lasting gut trouble that I am still
         | struggling with.
        
       | takklz wrote:
       | I get migraines when I drink too much water! Not even kidding.
       | Full blown visual aura followed by intense pain for a day.
        
       | FloorEgg wrote:
       | I got my first migraine in my early teens. I was over at a
       | friend's house and we were playing in the basement on a summer
       | day, then went outside where the sun reflected off a window into
       | my eyes.
       | 
       | It would start with a shimmering pattern obstructing my vision
       | where the bright light was, which would grow into a c shape and
       | get bigger until it surrounded my vision and then faded away.
       | About 15 min after the shimmering pattern faded the blistering
       | pain would start and last for about 5 hours, with lingering light
       | sensitivity until the next day.
       | 
       | I later realized that something about a rapid change in
       | brightness (from dark to bright) would trigger them for me.
       | 
       | Another time was triggered by a high school shop teacher lighting
       | a welding torch.
       | 
       | The best way to relieve the pain I found was to turn out all the
       | lights and dunk my head in cold water, which I discovered
       | eventually in desperation for relief.
       | 
       | I would only get them every few months, but when I did I would be
       | pretty useless for most of the day. I stopped getting them in my
       | early 20s. No idea why, but I am grateful. They sucked!
        
         | tim333 wrote:
         | I sometimes get shimmering patterns which I think they call
         | visual migraine or
         | https://en.wikipedia.org/wiki/Scintillating_scotoma but
         | thankfully mine don't go on to migraine proper. They often seem
         | set of by a bright light outside the center of vision like I'm
         | reading a book with sunlight coming in from 45 degrees.
        
           | fahrnfahrnfahrn wrote:
           | I've had fewer than a dozen episodes starting last year.
           | Luckily, like you, I have scintillating scotoma without
           | headache. I haven't noticed a trigger--they're just
           | spontaneous. A couple of years before, I had a couple of
           | episodes of binocular diplopia
           | (https://www.yalemedicine.org/conditions/double-vision).
           | Dunno if they're related.
        
           | Analemma_ wrote:
           | I've mentioned this before in previous HN threads about
           | scintillating scotomas, but it's worth repeating: in my case,
           | the issue was entirely due to excessive caffeine consumption.
           | When I got them frequently I was sometimes consuming upwards
           | of 450mg/day, when I cut intake way down they disappeared
           | entirely, and when I occasionally fall off the wagon and have
           | way too much that's when they come back.
        
           | jen729w wrote:
           | Exactly the same trigger here. I had one just the other day
           | at the pub. Sitting outside, under shade, but to my left was
           | a bright spot. It's weird how I can sense it arriving ...
           | something about the quality of my vision subtly changes, and
           | there it is.
           | 
           | Fortunately for me it isn't accompanied by a headache. It's
           | just really unsettling. At least now I've learned to
           | recognise them and I just try to chill out while it does its
           | thing.
           | 
           | (FWIW, also a tremendous consumer of caffeine here. But this
           | was at 17:00, a good 5 hours after my last cup.)
        
             | tw04 wrote:
             | For whatever it's worth, too much caffeine and dehydration
             | does this to me. Chugging about 48 oz of water and throwing
             | on a face mask for 30-60 minutes usually clears it up. If I
             | do "nothing" it takes significantly longer to clear up.
        
               | quackscience wrote:
               | I get the same, and all of these tend to be a trigger for
               | me too -- too much caffeine, dehydration, and rapid light
               | intensity change (like looking outside and then back to
               | my computer screen).
               | 
               | In addition to chugging water and staying in the dark
               | with a face mask, I've found that taking raw honey right
               | as it's coming on makes it go away rapidly.
               | 
               | My long term prevention is taking magnesium daily and LSD
               | once or so a year. Once I started doing that the
               | frequency went to almost zero, and whenever I don't do
               | that they start up again.
        
               | almuhalil wrote:
               | In my case it's the combination of too much caffeine,
               | dehydration, and intense exercise where my HR maxes out.
               | 2/3 risk factors will typically not be enough to trigger
               | one for me. HIIT workouts and soccer have done it in the
               | past.
               | 
               | The aura (with scintillating scotoma) starts coming on
               | usually an hour or so after the exercise is done, and I
               | know I've got about 15-20 minutes before the actual
               | migraine hits. Got prescribed Sumatriptan and it maybe
               | reduced the intensity by about 25%. I'll have to try the
               | water chugging, maybe with rehydration salts to speed up
               | absorption.
        
           | bregma wrote:
           | I've been getting scintillating scotoma for over 50 years.
           | They've changed character over the years from widespread
           | fortifications to virtually no scintillation at all but
           | always progress from a bright spot to a large blind spot to
           | an expanding toroidal blind region with vision restored at
           | the origin point until they pass out of my field of vision.
           | They used to lead to headaches and sometimes speech deficits
           | or other somatic experiences (like sizzling on my tongue and
           | lips) but now I just get mild abdominal discomfort. With a
           | couple of notable exceptions it lasts about an hour.
           | 
           | I have learned that while they're inconvenient, they're
           | harmless and I just generally continue with whatever I was
           | doing when they began. I have never been able to discern a
           | trigger: they appear to come on completely randomly.
        
             | elric wrote:
             | Exact same story here, including the occasional speech
             | problem. Well, I've only been getting them for 30 years.
             | It's always reassuring to hear this from people who have
             | been getting them for longer than me. They used to freak me
             | out when I was younger. Still worry me a bit when I get
             | multiple in a single week.
        
           | julian_t wrote:
           | I used to get these two or three times a year, but then I had
           | heart surgery last summer and had five in the first day after
           | I came round from the anesthetic, and two or three every day
           | for weeks after that. They've now settled down to one every
           | few days. Annoying, but they go away fairly quickly and just
           | leave me feeling a bit tired and headachy for a few hours.
        
             | h_squared wrote:
             | Same story for me, had a minor ablation procedure which
             | triggered a bunch of migraines that later settled down.
        
         | tclancy wrote:
         | That feels pretty similar to my story. I always put it down to
         | some kind of puberty changes.
        
           | xattt wrote:
           | Yes! At least some migraines are caused by whatever second-
           | order effect there is from hormonal changes.
        
         | e40 wrote:
         | Yep, I realized mine were caused by looking out the window
         | while I brushed my teeth in the morning. One day it was really
         | bright outside and really dark inside and the migraine started
         | almost immediately. More than a year and I keep the blinds
         | drawn while I'm in the bathroom in the morning and not a single
         | migraine!
        
           | mh- wrote:
           | This is interesting. I frequently had them triggered by
           | riding BART in the late afternoons in the winter, sun beating
           | in through the dirty windows. Going through the tube (dark)
           | and emerging in Oakland (raised track, clear view of the sky
           | on both sides) had a double-digit % chance of giving me a
           | migraine if my eyes were open at one point.
           | 
           | I can get them triggered by riding in a car in similar
           | conditions, too, especially if the windows aren't squeaky
           | clean. I frequently wonder why that is, something about the
           | remaining spectrum of visible light when the windows are
           | dirty?
        
             | error_logic wrote:
             | Reminds me of wearing non-prescription sunglasses despite
             | having myopia. It feels like the blurring of the world is
             | due to the glasses, even though they're actually only
             | blocking some of the light rather than distorting it.
        
         | dgacmu wrote:
         | I'm glad you shared this - I also have light triggered
         | migraines and I didn't realize there were so many others who
         | also did. :) huh! I take ibuprofen and two shots of espresso
         | and lock myself in a dark room and do deep breathing/relaxation
         | -- the latter seems to have been surprisingly helpful for me in
         | the last few years, and makes me wonder if my anxiety response
         | to having the initial aura was actually contributing to
         | worsening the migraine.
         | 
         | My favorite episode was when I went to my doctor, said "yeah,
         | it's good, I haven't had a migraine for like 6 months", and as
         | part of the physical he shined a pen light in my eyes ... and I
         | went home and developed a migraine. sigh.
         | 
         | (Fortunately, some time in my 20s, I stopped getting the
         | headache part for the most part and now just have aura -- which
         | renders me partly unable to see, alas -- and feeling pretty off
         | for a while.)
        
           | takomako wrote:
           | Have you tried cold brew? It has about 10x the caffeine of an
           | espresso shot. Espresso has the least amount of a caffeine of
           | coffee drinks. Cold water and long exposure extracts more
           | caffeine than hot water and short exposure. Source: I'm a
           | coffee nerd.
        
             | Talanes wrote:
             | The difference isn't typically that vast. At usual dilution
             | levels, drinking a 16oz cold brew would be slight caffeine
             | gain on the double-shot. Heat does extract caffeine better
             | that cold, which is why the shot is prepared in [?]25
             | seconds and the cold brew concentrate takes 12-20 hours.
             | 
             | Source:10 years experience as a working barista.
        
           | melllvar wrote:
           | There are OTC meds you can buy that are marketed as "migraine
           | relief" that are just acetaminophen + caffeine; my wife takes
           | that and it usually works to relieve the symptoms (if she can
           | catch it early enough).
           | 
           | Of course, then you take away the espresso - there's always a
           | trade-off :)
        
         | cdrini wrote:
         | Same! My understanding of migraines is that it's something to
         | do with blood pressure in your head. My hypothesis is that the
         | visual disturbances are your blood vessels dilating and
         | pressing against your retina. Then I think it can cause kind of
         | a runaway feedback loop of some sort that causes the blood
         | pressure to increase throughout your head, causing pain.
         | 
         | Thinking about it now, I wonder if the light trigger could be
         | the bright light causing minor damage to your retina,
         | potentially triggering an inflammation/repair response. The
         | fact that it happens when going from dark to light suddenly,
         | also makes sense, since your pupil is at its most dilated when
         | in the dark, meaning the most of your retina is
         | exposed/vulnerable. That might also explain why it always
         | starts in the periphery; because the edges of your retina are
         | likely less often exposed to light and potentially more
         | delicate -- but would be exposed if you see bright lights while
         | your pupils are fully dilated.
         | 
         | For me, I've found it's also closely related to irregular food
         | or sleep. And I find eating something with sugar or drinking
         | some water can reduce the likelihood of the visual disturbances
         | becoming a full-on migraine. My hypothesis is that these things
         | alter your blood chemistry/physics enough to interfere with the
         | runaway feedback loop that results in increasing blood
         | pressure. I imagine dunking your head in cold water likewise
         | works because it breaks the runaway process.
         | 
         | But this is all speculation.
        
           | tptacek wrote:
           | Just for what it's worth, the middle third of the article is
           | about the proposed limbic system causes of migraine.
        
         | beacon294 wrote:
         | I also discovered the dive / ice water reflex sometimes helped
         | my migraine. The reason I tested it is because caffeine
         | supposedly releases some chemicals related to the same
         | chemicals that are released when you vomit. Since my migraines
         | always ceased after vomiting, I used these other methods to
         | induce the same chemical response in the brain.
         | 
         | I now keep Excedrin migraine on hand (has caffeine). However,
         | my migraines completely ceased after I stopped using nasal
         | steroid spray and started with an allergy nasal spray.
        
           | wx196 wrote:
           | I underwent allergy treatment that stopped working, so I
           | decided to try steroid medication. After about four days, I
           | began experiencing unusual migraines every day. I had
           | migraines before, but they always came with a headache.
           | However, with the steroids, I started getting just very
           | strange optic auras. Everything began to sparkle out of
           | nowhere, becoming more intense until I had to close my eyes.
           | The symptoms stopped once I discontinued the steroid
           | treatment.
        
       | groos wrote:
       | I started having migraines at 8 years of age, several a week.
       | This persisted all through my life till 42 years later, I had a
       | blood pressure emergency where I ended up in ER with 190/100
       | blood pressure. Thankfully, it never repeated and was never
       | diagnosed but as a consequence I was put on Olmesartan, a blood
       | pressure medication that relaxes the blood vessels. Eventually,
       | the dose was reduced to the lowest, 5mg, once a day, to which I
       | added 240mg magnesium glycinate, which they sell in Costco. I
       | have been mostly migraine free since for several years and ones I
       | do get are mild compared to before.
       | 
       | My cardiologist, who prescribed the blood pressure medication, is
       | mystified saying that while beta blockers are a migraine
       | prevention medication, olmesartan isn't a beta blocker and maybe
       | it was just my (mild) hypertension which needed to be treated. I
       | doubt that I had hypertension when I was 8 but I'm just thankful
       | that decades of pain have come to an end.
        
         | fireflash38 wrote:
         | Hmm, I was prescribed Verapamil (calcium channel blocker, also
         | a blood pressure medication), and they helped reduce the
         | severity of my migraines with aura for a while. I eventually
         | went off it, and haven't had near as many since. Early twenties
         | was so awful for those migraines.
        
           | nooron wrote:
           | Did you find Verapamil had any mood altering or cognitive
           | properties for you? I take it for migraines. I think it makes
           | me a little more emotionally stable but a tiny bit slower
           | cognitively, especially in the mornings. It's a good trade
           | off, especially in light of how it basically stopped my
           | migraines, but it's one I have perceived.
        
         | nik9000 wrote:
         | I'm on a sartan and my migraine doctor thought it might help.
        
         | internet_points wrote:
         | Candesartan has been massively helpful and has very mild side
         | effects compared to beta blockers like metoprolol.
        
       | sepositus wrote:
       | I read a book a while ago. Unfortunately, I don't remember the
       | name (maybe AI can find it), but the premise was based on a
       | metaphor: there are multiple hot air balloons that, together,
       | affect the chance/severity of a migraine. Something like food,
       | sleep, stress, hydration, and one more. One of these "balloons"
       | filling up may be enough to trigger a migraine, while all of them
       | partially filling up can also trigger a migraine.
       | 
       | Sorry for the rough recall, but the point is that there may not
       | be a silver bullet solution simply because it's not one thing
       | contributing all of the time. I can trigger on all four of the
       | ones I listed. I've had migraines for a week straight now because
       | I recently developed tinnitus and am struggling to sleep.
       | However, I had a migraine the week before because I inadvertently
       | consumed red dye, which triggered massive inflammation in my
       | body.
       | 
       | So, for me, it's all about managing multiple things enough to not
       | get above the threshold.
        
         | dumbfounder wrote:
         | I don't think this is the same book but it is similar in its
         | thinking:
         | https://www.amazon.com/gp/aw/d/0761125663?psc=1&ref=ppx_pop_...
        
         | bonesss wrote:
         | A metaphor I heard once, second hand from a neurologist, was
         | that of making a stress stew. You add in the elements slowly
         | over time into the pot -- barometric pressure, painful
         | perfumes, an odd sleeping position, some traffic, marital
         | issues, whatever -- and then at some ill-defined point it
         | crosses a threshold into being a proper stress stew (ie a
         | migraine).
        
       | jcAUS wrote:
       | long-time listener, first-time caller on HN. I've had migraines
       | since I was a teen. Full blackout vision, then debilitating
       | headache for 48 hours. About 18months ago I cut out food
       | containing thickening agents (Xantham gum aka 415, et al). Have
       | only had a migraine since then when I've had food containing
       | these (which seems to be an increasing number of foods). I don't
       | suggest it's a cure all, but worth trying for others out there.
       | I've sat in job interviews, my wedding, kids' events dreading
       | having one occur.
        
       | dumbfounder wrote:
       | I have been diagnosed with vestibular migraines. No pain, just
       | dizziness and brain fog and vision issues (feels like my eyes
       | don't point in the same direction). I also have a doctor that
       | says I have symptoms of mold exposure (lots of correlative
       | testing and also house testing and remediation). I have also been
       | diagnosed with temporal lobe epilepsy by my neurologist, but my
       | mold doctor says that is consistent with mold exposure. I also
       | have a vestibular degradation, one side of my balance center is
       | damaged. I think all of it is related and linked by inflammation.
       | I do think that mold is part of the story, but definitely not all
       | of it. Anti seizure medication helps a lot. Ubrelvy (a gepants)
       | also helps a lot. Getting the right kind of sleep and exercise
       | and staying hydrated also all help. I am nearly 50 and this a new
       | thing that has happened in the last 2-3 years. Was not fun to go
       | through this on the tail end of running a startup. The brain fog
       | was debilitating. I am now 80% better with meds (and a shit ton
       | of supplements) but still on the journey to figure out how to get
       | back to normal and off all the meds. I do think it is
       | inflammation related but it could be one of a zillion things, or
       | a combination of many.
        
         | graeme wrote:
         | Have you tried vestibular rehab? Essentially a series of eye
         | tracking + neck mobility exercises that support the visual and
         | vestibular system.
        
           | dumbfounder wrote:
           | Yes. A lot of it. It was maybe 10% effective at best.
           | 
           | The way one ENT described it, I have 40% degradation on one
           | side. If it's constant, your brain adjusts and you are
           | essentially ok. If something happens to vary that then your
           | brain can't adjust. My theory is that you add inflammation or
           | migraines or epilepsy or all of it and the brain can't
           | compensate.
        
         | whoiswes wrote:
         | Wife has been struggling with vestibular migraines for about 20
         | years. It really came to a head about 5 years ago, and we spent
         | the following three years seeing specialist after specialist
         | and trying around a dozen different medications. During this
         | time she had daily flare-ups and missed a lot of work and spent
         | most days in bed or on the couch.
         | 
         | What ended up working in the end? We finally got into Mayo, and
         | they suggested an SSRI (at a fairly high dose). She also
         | figured out that she has a few food triggers (yogurt and
         | freshly baked bread are 2 bad ones). She also discovered she
         | has double vision, and now wears prism glasses. We think the
         | combination of double vision and whatever brain chemistry
         | imbalance she had was "overloading" her vision and vestibular
         | systems, and she would basically just shut down. Treating both
         | of those seems to have (mostly) alleviated things for her.
         | 
         | I completely understand what you've gone though and how
         | frustrating it is, especially given the very vague criteria for
         | diagnosing and treating vestibular migraine.
        
       | caitlinface wrote:
       | I've suffered from migraines all my life. It worsened as I've
       | gotten older. One day long attacks turned into three day long
       | attacks. Then turned into five day long attacks. I've taken
       | various preventatives and abortives over the years to varying
       | success. It runs in my family so I never thought to see a
       | neurologist for them. A couple years ago I had a bad string of
       | them and my medicine wasn't really touching it, so I finally
       | decided to see a headache specialist. The doctor very quickly got
       | me started one of these anti-CGRP medications.
       | 
       | Almost immediately, I dropped to 0-1 attacks a month, and when
       | they do happen they are both less painful and my other medicine
       | knocks them out fast.
       | 
       | Literally life changing.
        
         | usefulcat wrote:
         | My mom had migraine headaches pretty much all her life. For
         | many years she had been seeing the same doctor for her
         | headaches.
         | 
         | Then she got old enough that she was on Medicaid, and she had
         | to stop seeing that doctor because he didn't accept Medicaid.
         | So she found a different doctor. Different doctor prescribed a
         | different treatment and lo and behold, her headaches pretty
         | much went away after that.
        
           | dumbfounder wrote:
           | Moral of the story: if your doctor doesn't make you feel
           | better try another one.
        
           | cf100clunk wrote:
           | My paternal grandmother was a migraineur, but back in the
           | 1930s she was treated as a "hysterical" woman and given
           | opiates. Her battles could not be overcome and she lived a
           | short life. Thankfully the treatments have evolved.
        
             | cf100clunk wrote:
             | Alors, I've been reminded that I should have referred to
             | her as a migraineuse (feminine).
        
         | geye1234 wrote:
         | Yep, I was exactly the same. It took me decades to get
         | diagnosed, then several more years before I saw a neurologist.
         | Now I'm on a CGRP blocker, I hardly get them at all.
         | 
         | In addition, my anxiety/depression is almost gone and my ADHD
         | is about 50% improved (I'm not able to tolerate anti-ADHD
         | meds). I love Nurtec. Expensive, but worth every penny. If my
         | insurance didn't cover it, I'd pay out of pocket without a
         | second thought. It's that good.
        
         | 01100011 wrote:
         | I had them in my 20s on a weekly basis but since I could stave
         | them off with massive water intake I thought they were
         | something else. I didn't get optical symptoms, it was just a
         | really bad headache, nausea and chills that felt like a bad
         | hangover. It wasn't until my 40s when I started getting optical
         | migraines (which are scary as hell since they mimic a stroke)
         | that I went to a dr and he diagnosed me. Apparently it's common
         | for migraine sufferers to transition to optical migraines when
         | they're older.
        
           | timc3 wrote:
           | This is exactly the same as my experience. The first optical
           | migraine was super scary.
        
         | ErigmolCt wrote:
         | Did you have any side effects from the medication, or was it
         | pretty smooth sailing?
        
           | ne8il wrote:
           | I've been on Qulipta (a CGRP drug) daily for about a year
           | now. It started working pretty much immediately, and I cannot
           | think of a single side-effect in use, other than that you
           | will have a withdrawal period pretty much immediately if you
           | miss a dose.
           | 
           | Before that I've used Rizatriptan to treat rather than
           | prevent (works well, but can cause brain fog, mood swings and
           | GI issues). In order to get approval for the CGRP I had to
           | try lower-cost drugs like Verapamil (a calcium channel
           | blocker) which had no effects at all, positive or negative,
           | and Topiramate, which is the single worst medication I've
           | ever used. Compared to all of those, the CGRP is a miracle
           | and has been life-changing.
        
             | megaman821 wrote:
             | There a some small side-effects with Quilipta. I was a bit
             | low energy for a couple a weeks until my body got used to
             | it. Also, it is a mild appetite suppressant. I seem to be
             | able to miss doses of a day or two just fine though. Nurtec
             | also works well for me as an accute migrate treatment.
        
         | yoaviram wrote:
         | Same pattern for me. About a year ago migraines escalated to a
         | few times a week. Debilitating. I started searching for a
         | solution and discovered this book [1]. It basically recommends
         | a low carb or even a keto diet. After three weeks migrants
         | reduced to once every three to four months, and mostly because
         | I'm cheating on the diet. Life changing.
        
           | stewarts wrote:
           | Low carb/keto also had dramatic effects on frequency of
           | migraines/headaches for myself. CPAP however, has been even
           | more life changing in that regard for myself. From headaches
           | 4-7 days of the week to fewer than 1 per week.
           | 
           | Some confounding variables on diet/weight loss/sleep quality.
           | But I don't care, things are better and I'm happier for it.
        
           | tharkun__ wrote:
           | This is what helped me as well, plus probiotics to turn my
           | gut flora around.
           | 
           | I have a nagging feeling that "migraine" is actually not an
           | actual single disease. It's rather a syndrome, i.e. a set of
           | symptoms people have for various different reasons.
           | 
           | Through keto and the probiotics experimenting, I've learned
           | much more about how the whole gut thing "works" (very much
           | not an exact science!) for myself and that doctors in general
           | are clueless about it themselves. Or ignorant. Or don't want
           | to deal with anything they can't just diagnose with a 5
           | minute talk.
           | 
           | My migraines are food related. Without the probiotics I could
           | somewhat control when I might get one by not slipping and
           | eating something tasty but bad for me (like lasagna two days
           | in a row - tomatoes bad). Add to this the fact that food in
           | many cases takes two days to go through your system, eating a
           | food and getting symptoms is delayed. Evacuating the food
           | from your system would also cure the acute migraine headaches
           | and other symptoms. With the right probiotics I can now eat
           | all the lasagna I want and throw in blue cheese and red wine
           | as well!
        
       | kazinator wrote:
       | > _When May started researching migraine in the 1990s, the
       | leading hypotheses were that migraine was either a psychological
       | issue or a vascular headache disorder, with throbbing pain caused
       | by dilation of blood vessels. The psychological associations came
       | with stigma, May says. [...] A lot changed in the 1990s, when May
       | and others began conducting brain scans of people with migraine._
       | 
       | Sure, who the hell is this guy, and his discovery of the cortical
       | spreading depression phenomenon:
       | 
       | https://en.wikipedia.org/wiki/Aristides_Le%C3%A3o
        
       | apprentice7 wrote:
       | Hello, fellow migraine sufferers. I sincerely want you to read
       | the fantastic essay "In Bed" by Joan Didion. It is a fantastic
       | reflection on what it is like to have migraines and it makes me
       | cry every time I read it because it makes me feel seen and
       | understood.
       | 
       | "For I had no brain tumor, no eyestrain, no high blood pressure,
       | nothing wrong with me at all: I simply had migraine headaches,
       | and migraine headaches were, as everyone who did not have them
       | knew, imaginary."
       | 
       | Read it; it's a google search away. You'll thank me.
        
       | mccoyb wrote:
       | Anti-CGRP medicines are life changing.
       | 
       | The only medicine I've used that has all but completely
       | eliminated my migraines during usage (Aimovig).
       | 
       | Unfortunately, to get these -- you have to provide an arm and a
       | leg to insurance, even when a neurologist is vouching for you.
       | 
       | Nothing makes me consider violence more than meeting with a
       | highly educated, vetted, practitioner of medicine -- having a
       | conclusive conversation about a treatment plan, and then having
       | my fucking insurance say "ope, sorry -- you have to prove you
       | need this medicine by trying anti-depressants (which might
       | incidentally help, but not designed for migraines), or this other
       | thing which also may incidentally help (but not designed for
       | migraines)"
       | 
       | Get this -- I got a prescription for Aimovig, all positive
       | results (for a year and a half) and my insurance is still getting
       | in the way of fulfilling the script (each month). If I miss the
       | dose, I get a massive rebound migraine -- and I've missed several
       | doses because my insurance wants to send another letter to my
       | neuro "hey are you claiming this is still worth it?"
       | 
       | What does one do here? Lawyer up?
        
       | w10-1 wrote:
       | If you've suffered, seek a current expert (e.g., a neurologist
       | migraine specialist who has recently completed training).
       | 
       | The newer CGRP inhibitors have been highly effective, but that
       | also has made some specialists grow stale in their assessment
       | skills.
       | 
       | Pain is emotionally debilitating, but sorting out complex chronic
       | migraines takes persistence, patience, and an excellent
       | diagnostician. It can take a few long-term trials of treatment
       | and environmental/behavior changes. Be a good patient: bring
       | accurate contemporaneous journals and openness to new
       | suggestions, and stick with an agreed regime pending re-
       | evaluation. Above all, don't just try to power through or mask
       | the pain.
        
       | teaearlgraycold wrote:
       | I can get migraines, but they're "silent migraines" which means
       | there's little or no pain aspect. Thankfully it was pretty
       | straightforward to root out the trigger - caffeine. I still love
       | coffee, but I'm decaf only now. I drink Equator Coffee's natural
       | process decafs.
        
       | ChrisMarshallNY wrote:
       | I get one about once a decade. My mother got them frequently.
       | 
       |  _Real_ migraines absolutely suck. A lot of folks describe
       | regular headaches as "migraines," but they are a pale imitation
       | of the real thing.
       | 
       | In my case, they usually start in the morning, but don't get
       | really excruciating until early evening. I usually figure out
       | it's a migraine, about lunchtime. Around 9-10PM or so, I puke,
       | then the headache starts leveling off, until I fall asleep. The
       | next day, it's as if nothing happened.
       | 
       | I did "short-circuit" one, the last time one started, using
       | advice that I remembered from my mother. I sat in a recliner, in
       | a dark room, with a towel wrapped around the top of my head and
       | eyes (probably looked ridiculous). It's important not to engage
       | my eyes at all. After a couple of hours, the headache stopped.
        
         | notfed wrote:
         | On the contrary, I'd argue that migraines are probably much
         | more common than diagnosed, rather than the other way around.
         | Migraines, much like seizures, vary in both symptoms and
         | severity.
        
           | ChrisMarshallNY wrote:
           | Not my area of expertise, but anecdatally, everyone that I
           | know, that has suffered from diagnosed migraines, has had
           | really crippling symptoms. They seem to be fairly universally
           | severe. I have had headaches all my life (including ones
           | related to a brain tumor, back in the 1990s. The migraines
           | don't seem to be related to that tumor, which was treated
           | with surgery). In my personal experience, the comparison is
           | night and day. There's a clear difference.
           | 
           | Basically, a migraine is a "day-ending" event. In my case,
           | I'm fortunate that I can still get stuff done in the morning,
           | but after lunch, the day's pretty much a write-off.
           | 
           | I'm really grateful that they are so rare (I've had three
           | full-term, and one "aborted" one, in the last 30 years). My
           | mother used to get one or two a month, and her day ended
           | fairly early. When I was a teenager, I got them more
           | frequently.
        
       | digitalsushi wrote:
       | my wife would get a migraine every single day around 1pm. she
       | scheduled her college around them. she did a bunch of genetic
       | tests, and (this is not science to me, i dont know the process at
       | all) she ended up trying a methylated vitamin b complex, 8333%
       | usda dose, and they dried right up forever. i feel for anyone
       | dealing with them. i got my first one 7 years ago and learned i
       | am sensitive to soybeans. i can pop some raw soybeans into my
       | mouth and have a visual aura and migraine within 30 minutes, it's
       | fascinating.
        
       | Foofoobar12345 wrote:
       | I used to get frequent migraine attacks - there were times when I
       | would be down 3 days in a week, just unable to be productive. A
       | lot of it was induced by stress.
       | 
       | I then tried something novel - I took some LSD. I had an intense
       | psychedelic trip, dug deep into my psyche, realized I was a giant
       | ball of anxiety. The anxiety's root cause was ultimately a fear
       | of mortality (around the same time, my dad was going through a
       | terminal illness, we spent many years in and out of ICUs, so a
       | lot of that had soaked into me). I had to come to terms with my
       | own mortality, which happened when I just "melted" away and lost
       | sense of self momentarily, and once I did, I felt so much lighter
       | as I came out of the trip.
       | 
       | My migraines stopped right then and there; I kid you not. I
       | didn't get a single headache for the next 4-5 years, and in
       | general, I was also a lot more balanced and at peace, even though
       | I went through some highly stressful times. It was miraculous.
       | 
       | Of course, life has a way of creeping up on me, and I do get
       | migraines occasionally, but when I do, I know how to stop them -
       | I just need to slow down, meditate (not feel-good meditations all
       | these meditation apps promote, but actually meditate and _feel_
       | your muscles relaxing). That single LSD trip taught me how to
       | relax myself physiologically.
       | 
       | Not saying this is going to work for everyone, just sharing my
       | personal experience. Please keep in mind that playing with
       | psychedelics is like playing with fire. Exercise caution.
        
         | xvedejas wrote:
         | Even sub-psychedelic doses of tryptamines is known to have an
         | effect on certain migraines and cluster headaches:
         | https://en.m.wikipedia.org/wiki/Triptan
        
           | 3D30497420 wrote:
           | I take a triptan for mine (naratriptan) and it has helped.
           | Certainly not a cure though.
        
           | ulrikrasmussen wrote:
           | Can this family of drugs even give a psychedelic experience
           | at higher doses? They are acting on 5-HT1B and 5-HT1D, not
           | the 5-HT2A receptors that psychedelics act on.
        
         | Aurornis wrote:
         | As a counter-antidote: I know several people now who have
         | experimented with psychedelics with the goal of addressing
         | mental health issues who ended up significantly worse.
         | 
         | One of them got stuck with a nagging feeling that the world
         | wasn't quite real that lasted for a very long time, which
         | resulted in a lot of anxiety.
        
           | Foofoobar12345 wrote:
           | Yup - they can also give you migraines (or worse) if you
           | introduce bugs into the "software", just as I was able to
           | debug my problems away.
        
           | tkzed49 wrote:
           | Depersonalization and derealization are truly awful. Having
           | experienced them for non-psychedelic reasons, it's almost
           | indescribable.
           | 
           | Sometimes people say "seeing events in third person". My
           | experience was that my consciousness and actions were
           | completely disconnected from my observations of reality.
           | Like, I questioned whether I had any influence at all over my
           | existence. Basic, predictable events were suddenly uncertain
           | and terrifying. It left me with no mental capacity to do
           | anything but uneasily exist.
           | 
           | With treatment, it goes away gradually over months. I never
           | want to go back there.
        
             | vasco wrote:
             | One wonders if that's how it actually is and the rest is
             | just the brain fooling us into having control by way of
             | rationalizing the actions we were going to do anyway.
        
               | encipriano wrote:
               | We kinda know its like that dont we. Perhaps those who
               | suffer such condition see throuh the abstractions our
               | brain makes. Like seeing things in a rawer form that
               | doesnt align well with more normative views of society.
        
               | Galaxeblaffer wrote:
               | > Like seeing things in a rawer form that doesnt align
               | well with more normative views of society.
               | 
               | Psycedelics in a nutshell
        
               | iamacyborg wrote:
               | There's certainly a lot of research and a lot of
               | philosophical thought leaning in that direction.
        
               | shkkmo wrote:
               | Without the lies our brain tells our consciousness, we
               | couldn't function. Even core stuff like the way that we
               | see or our experience of choice, are dependent on our
               | brain fooling us in some way.
               | 
               | Luckily, we an pretty good at being hypocritical. This
               | allows us to learn and think about this stuff while still
               | believing the lies.
        
               | lo_zamoyski wrote:
               | This suffers from the homunculus fallacy.
        
             | quackscience wrote:
             | It definitely depends on the person and the state of mind
             | they have when they go into it. I've had really
             | overwhelming de-personalization episodes on LSD as well and
             | they were extremely positive, life transforming
             | experiences. I had studied and practiced Buddhism for years
             | prior to having those experiences, though, which helped me
             | integrate what was happening. It was like all of a sudden
             | getting a direct experience of what was previously just
             | words and philosophy -- "oh, _this_ is what he was talking
             | about. "
             | 
             | Had I gone into it totally blind with no way to frame it it
             | probably would have been a nightmarish scenario though.
             | There's a reason why Right View (samyak-drishti) is the
             | first of the 8 Noble Truths [1] and the one really
             | emphasized in the beginning of your Buddhist practice.
             | 
             | [1] https://en.wikipedia.org/wiki/View_(Buddhism)
        
           | dmos62 wrote:
           | There's something to be said about psychedelics and
           | introversion in general being a two-edged sword. There's also
           | something to be said about how we get into trouble when we
           | consider beliefs or abstract feelings as something outside
           | our control.
        
         | ErigmolCt wrote:
         | Stress is definitely a huge migraine trigger for me too, and
         | it's really interesting how that trip helped you get to the
         | root of it. I haven't tried psychedelics, but I can relate to
         | the idea that learning to truly relax (not just surface-level
         | relaxation) can make a big difference
        
         | shaky-carrousel wrote:
         | Stress is a common migraine trigger.
        
         | wonderwonder wrote:
         | I had a similar experience but with simple Marijuana. I was
         | getting migraines every week for months. Specifically my eye
         | would catch light at some strange angle and it would almost
         | burn itself onto my retina (massive light sensitivity). I was
         | also highly stressed at the time.
         | 
         | I was laying in bed with a migraine on a Saturday early
         | afternoon. Smoked some pot (I am not a day smoker, generally
         | pretty sober during the day) and then sat down. I just told
         | myself that this was stupid, I live an incredible life, have a
         | family that loves me and its all self induced and I was done
         | with it. Forced myself to get out of bed and just started
         | moving. Trudged my way through it that day and have not really
         | had a migraine since. This was years ago.
         | 
         | I have occasionally had that initial flash of light that tells
         | me a migraine is coming (always while sitting down to work so I
         | know its stress related). As soon as it hits, I close my eyes
         | and just will it to go away. Has been pretty successful. A
         | couple of times I have had to sit there for 10 minutes for the
         | lens flare (for lack of a better word) to go away. This has
         | happened maybe twice a year for the last ~4 years.
         | 
         | Not saying its self induced / stress for everyone but this
         | worked for me.
        
         | slibhb wrote:
         | This is where pseudoscience comes from. You dropped acid and
         | think it helped you but you probably tried many different
         | things before acid which "didn't work". In all likelihood the
         | acid had nothing to do with it; it was just a coincidence that
         | your symptoms improved.
         | 
         | Also, it's common to have a lot of migraines for a period in
         | your life and then stop having them. Or sometimes the reverse.
         | I used to get very painful migraines about twice a year.
         | Eventually that stopped. I still get migraines a couple times a
         | year but they're quick "silent migraines" i.e. not painful,
         | just annoying and disorienting.
        
           | quackscience wrote:
           | Possibly, but there are a lot of people that self-administer
           | LSD for migraines who say it helps tremendously. I'm also one
           | of those people. Between occasional LSD and daily magnesium
           | supplementation, my migraines are very infrequent these days.
           | 
           | https://www.science.org/content/article/lsd-alleviates-
           | suici...
        
           | mettamage wrote:
           | > This is where pseudoscience comes from.
           | 
           | I disagree, if it stopped it stopped. It could be from
           | something else, but his LSD intake is the most likely
           | candidate. It would become pseudoscience if he or she would
           | claim that this will work for everyone.
           | 
           | Also, don't forget that science can make a similar flaw. Just
           | because a drug works on average, doesn't mean that it will
           | work for you or that it won't have any negative side effects.
           | Human variation can be quite big with certain things.
        
           | dimal wrote:
           | This is also how many scientific discoveries start. An n=1
           | observation. Then more observations, then more validation.
           | This is how we ended up getting ketamine for depression.
        
           | AnthonBerg wrote:
           | Are you aware of the ample research and scientific knowledge
           | on the interplay between the 5-HT2A receptor and
           | inflammation, vasomotor effects, and effects of 5-HT2A
           | activation on migraine and cluster headaches?
           | 
           | In... all likelihood you do not?
           | 
           | This review paper is particularly interesting, especially
           | because nobody is discussing this and nobody has read it: htt
           | ps://www.frontiersin.org/journals/immunology/articles/10....
           | 
           | The author is a serious person and this is a significant
           | review paper of a solid and broad research foundation.
           | 
           | There are also studies on 5-HT2A agonists ("psychedelics") on
           | migraine and cluster headaches directly.
        
         | DiscourseFan wrote:
         | Psychedelic treatment of migraines has nothing to do with the
         | trip, however. Be careful of confusing your feelings with your
         | actual health, they are not always related.
        
           | snozolli wrote:
           | _Psychedelic treatment of migraines has nothing to do with
           | the trip, however._
           | 
           | What does this even mean, and where is your proof?
           | 
           |  _Be careful of confusing your feelings with your actual
           | health, they are not always related_
           | 
           | Why are you talking down to people, oh sage one?
        
             | DiscourseFan wrote:
             | https://en.m.wikipedia.org/wiki/Triptan From a comment
             | above.
             | 
             | And to respond to the latter, how many people are diagnosed
             | every year with terminal cancer after a routine doctor's
             | appointment? I didn't believe I needed an example.
        
           | smeeger wrote:
           | true. the one time i used lsd i had a horrifying bad trip,
           | like a waking nightmare. the kind of bad trip that people die
           | from. but my migraines completely stopped for five years
           | afterwards.
        
         | amelius wrote:
         | > actually meditate and feel your muscles relaxing
         | 
         | Could you provide a short description of how you approach this?
         | E.g. how do you start and which muscles do you focus on, etc.
        
       | perrygeo wrote:
       | I spent most of my life thinking "migraine" was just a really bad
       | headache. Until I started getting migraines. The best way to
       | describe it is a band of white hot pain, almost a stabbing
       | sensation. It started behind the eyes and would spread
       | everywhere. Not confined to my head, a full-on nervous system
       | meltdown: extreme light sensitivity, blurred vision, trouble with
       | balance and coordination, nausea, numbness, and residual effects
       | that lasted over a day. With a migraine, there is no "take an
       | advil and power through" - you sit in a dark room and pray.
        
       | theoryofx wrote:
       | Just throwing it in here in case it helps someone: if you have
       | migraines, get an eye exam to check if you need glasses (you
       | might not realize it!) and that your prescription is still
       | sufficient.
        
       | rakejake wrote:
       | I was diagnosed with migraine as a kid when I was 10. The doctor
       | made me undergo a battery of tests including a contrast CT scan
       | that consumed aj entire day, only to confirm at the end of the
       | day that it was migraine. The migraines weren't even that
       | debilitating but my mom was just being extra careful.
       | 
       | After that, I still got headaches at a good frequency and tried
       | all sorts of specialists from orthos to opthalmologists, all of
       | who checked their areas of the body and said I was perfectly
       | normal. The one doc I didn't see was a gastro and this was a
       | mistake.
       | 
       | Eventually I grew older and realised first that my headaches were
       | always preceded by some sinus congestion and milk was a trigger
       | of said congestion. So I switched to lactose free milk and that
       | helped.
       | 
       | Eventually I realised that I was a chronic acid reflux patient,
       | that a lot of small symptoms I had had over the years (a feeling
       | of something stuck in the throat, congestion etc) were basically
       | just the gut throwing up acid, or more accurately LPR/silent
       | reflux. The reflux was the actual trigger of my headache. So my
       | usual medication of Paracetamol, or worse, ibuprofen was actually
       | making it worse in the medium/long term.
       | 
       | I switched my strategies to fixing the gut/acid reflux instead of
       | treating the headache. The max I do nowadays is 325mg of
       | paracetamol if I need to sleep and the pain doesn't let me.
       | Ibuprofen is a nuclear option that I haven't resorted to in
       | years.
       | 
       | The gut issue is still not resolved, I suppose years of damage to
       | the oesophagus takes time to heal, so I'm still prone to reflux
       | but I make do with a bland diet, avoiding triggers like milk and
       | resorting to PPIs for short bursts during an attack. Oh and I
       | also do the bending while swallowing trick that was on HN
       | sometime back, which has helped immensely.
       | 
       | My headaches are mostly a thing of the past. Haven't had a
       | debilitating one in years.
        
         | ragtagtag wrote:
         | > I also do the bending while swallowing trick that was on HN
         | sometime back
         | 
         | Could you share the link for this, if you can find it?
        
           | beAbU wrote:
           | Dont have the hn discussion link, but it was this paper that
           | was posted.
           | 
           | https://pmc.ncbi.nlm.nih.gov/articles/PMC9106553/
        
         | genewitch wrote:
         | Gerd and the like are sometimes caused by too little acid.
         | Maybe your GP can discuss HCl pills to take if you feel a flare
         | up coming?
         | 
         | I only get bad reflux a few times a year and I use baking soda,
         | so I never think to buy HCl at a pharmacy.
         | 
         | Best of luck.
        
       | Wojtkie wrote:
       | Migraines being more than a headache has been the norm for at
       | least 15-20 years. I remember hearing about how cluster headaches
       | could be treated with psilocybin. I'm not able to access the rest
       | of this article, but what's the new thing here? We already knew
       | for years its not "just a headache"
        
       | ricardonunez wrote:
       | Commenting to save this for post for later. I suffer from
       | migraines regularly. I will try some of the suggestions here.
        
       | wsc981 wrote:
       | I tend to get migraines occasionally. For me the trigger is
       | stress. So if I can try to avoid stress, I wouldn't get migraines
       | as quickly. Sadly, in modern life it's sometimes hard to avoid
       | stress.
       | 
       | Maybe 5 years ago, to treat my migraines, my girlfriend advices
       | me to visit a massage therapist in Pattaya, as he's helped many
       | people, Thai and foreigner, to get rid of migraines. I had a
       | message session at his shop (including a lot of neck and head
       | massages) and he gave me some herbal medicine to eat for 1 or 2
       | months. Afterwards, didn't have migraines for a couple of years.
       | But the migraines came back, I think about 2 years ago. I might
       | visit the message therapist again in the future if we plan to
       | visit Pattaya (we live in Chiang Mai province, so it's like 800
       | km away).
       | 
       | I know of a girl in our village who also had a lot of migraines.
       | She visited some kind of Chinese medicine doctor in Chiang Mai.
       | He made some small holes in the head, blood would go outside. Not
       | sure how many sessions the girl got, but from my understanding
       | her migraines are gone now.
       | 
       | My migraines are usually as follows:
       | 
       | - usually lasts for around a day
       | 
       | - sometimes one side of the brain (temple area) is very painful
       | (like a drill inside), sometimes both sides
       | 
       | - arteries around the area in brain where is pain are visibly
       | thick
       | 
       | - pain in head & neck area, not so much in rest of body
       | 
       | - sensitive to light
       | 
       | Showering in hot water helps relieve the pain a bit, my guess is
       | because it might improve blood flow. I tend to take hot showers a
       | couple of times a day during migraine attacks.
       | 
       | Other things that seem to relieve a bit are ginger tea (fresh
       | ginger), tiger balm on pain area in head & head and neck
       | messages.
        
         | fi358 wrote:
         | I have also noticed that for some reason hot showers and also
         | shoulder and head massage help seem to help a lot, but only
         | about as long as I am in the shower or have the massage. And
         | also putting Vicks VapoRub on scalp seems to help a lot, but it
         | is quite messy. However, a triptan medication I have started to
         | use recently, seems to help even more.
        
       | jongjong wrote:
       | I get a migraine with aura about once every 6 months. It can last
       | between a few minutes to several hours. When this happens, part
       | of my field of vision disappears randomly and it becomes
       | difficult to focus on anything or read. Then after the aura, I
       | get a bad headache.
       | 
       | Sometimes, if I start to feel sensitive to light (a sign that I'm
       | about to have a migraine aura), I take a paracetamol and it
       | prevents it completely. The trick for me is to catch it early and
       | notice the signs. My migraines seem to correlate with my stress
       | levels, too much thinking and/or insufficient sleep.
        
       | beacon294 wrote:
       | I had migraines which ceased when I switched from a steroid nasal
       | spray to an allergy nasal spray. I guess the steroid spray was
       | not good for my brain.
       | 
       | Edit: I even reintroduced the spray 2 years later (out of allergy
       | spray) and had another migraine. It was surprising, as I only
       | used it for a few days.
        
       | elliotto wrote:
       | https://archive.md/Apbxw
        
       | taeric wrote:
       | I used to wonder if the headaches I have had were migraines. Then
       | I had the kind where you go blind for a few minutes, followed by
       | a migrain. Was the worst headache I've ever had, but I was so
       | glad to have my vision back.
        
       | anonzzzies wrote:
       | I used to have very many (multiple a week) and was under
       | specialist care for it in my 20s. Turned out to be stress though
       | (doctors didn't buy this but couldn't find any other reason
       | either, but once I stopped going to the office, I have had 0; I
       | stopped going 25 years ago and had 0 for 25 years). I found what
       | killed them almost immediately; 1 shot of vodka. When I saw the
       | lines and the auras starting to come (usually tunnelvision and
       | some vague jagged lines would announce an oncoming attack), I
       | would immediately knock down 1 shot of vodka and it would go away
       | while just causing a slight headache, but none of the rest of the
       | very bad things I would otherwise have like double vision,
       | splitting cluster headaches, auditory features, dizziness and
       | tingling in my face, some of that lasting for days. I would all
       | skip that with 1 shot. Just not having them is nicer though;
       | whatever helped, I am very happy I discovered it relatively early
       | on.
        
       | lifeinthevoid wrote:
       | I started having migraines in my late teens after drinking too
       | much alcohol at parties, I used to think they were hangovers. It
       | was only much later, after getting migraines in daily life, I
       | found out after visiting a neurologist that those hangovers were
       | migraines. Been having frequent migraines ever since, most of the
       | time triggered by stress. Often I'd have attacks 3-4 times a
       | week, fortunately the intensity is not crippling, more like a 6-7
       | out of 10. And now the good part, I have been supplementing Omega
       | 3 and Magnesium during the last couple of months and haven't had
       | a severe attack since. It's worth trying out if you suffer
       | frequent attacks like I did.
       | 
       | edit: my experience with sumatriptan, is that it helps stave off
       | an attack, but frequent use increased the frequency of my
       | attacks, leading to almost daily attacks, so I stopped taking it.
        
         | genewitch wrote:
         | Just so people are aware there are several types of magnesium
         | supplements and they all do different things. One of them is
         | for relieving constipation and will not help with migraines,
         | probably.
         | 
         | For instance I've recently started trying magnesium glycinate
         | as a sleep aid.
         | 
         | Anyhow I don't know which is which so I look it up.
        
           | lifeinthevoid wrote:
           | It's glycinate too.
        
       | ErigmolCt wrote:
       | As someone who deals with migraines, this article really hits
       | home. I'm glad there's progress being made, but it's also a bit
       | disheartening to see how much we still don't know
        
       | outime wrote:
       | I tried to find this advice in the thread but couldn't, and I'm
       | surprised since it's surprisingly common!
       | 
       | Some sweeteners such as aspartame can trigger migraines (also
       | some gut issues) depending on the quantity and person. While most
       | of the people can take them just fine in principle, others suffer
       | migraines a while after taking them. In my case, this was a
       | relative who suffered a lot until finding out by pure chance that
       | certain sweeteners where the reason, but you can find countless
       | cases.
        
         | genewitch wrote:
         | When I was a child I couldn't drink diet soda and then go play
         | outside during the summer, I'd get a wicked headache. I've
         | never had a migraine, based on the descriptions I've heard.
        
       | alkonaut wrote:
       | Lucky enough to get really quick relief from over the counter
       | migraine meds (triptanes) at even tiny doses. Life changing when
       | I realized I didn't have to do just obscene amounts of ibuprofen
       | and coffee for pretty poor results, and even a half of these tiny
       | pills worked.
        
         | stackedinserter wrote:
         | Careful with them, they can trigger medically-induced migraines
         | if overused. I did that mistake and it went to 3 days migraines
         | every week (and 3x10mg + more every week)
        
       | art0rz wrote:
       | Reading this as I'm just coming down from a migraine. I've been
       | getting them since I was a young teen. I get migraines with aura.
       | They used to last for hours. Sometimes I get them multiple times
       | per week, then they disappear for months/years and suddenly will
       | get them again. No significant life or dietary changes in
       | between. I've never been able to pin down what causes them.
       | 
       | These days they've become much more manageable. The aura and
       | headache part takes 30-60 minutes as opposed to 5+ hours when I
       | was a teen. I do experience brainfog, fatigue, dizzyness and
       | nausea for 24+ hours afterwards, but at least I'm not stuck under
       | the covers for hours.
        
       | piperly wrote:
       | I had a migraine for more than 15 years. After quitting caffeine
       | completely as a self-experiment, it never came back. When the
       | migraine came, I had it for at least 3 days without improving. So
       | I had to take something with Triptan, like Dolortriptan.
        
         | geye1234 wrote:
         | The book "Heal Your Headache" by David Buchholz which, while a
         | bit dated, has some good advice, recommends completely quitting
         | caffeine. It talks a lot about diet, but it has the strongest
         | words for caffeine. It considers it the worst of the food
         | culprits.
         | 
         | It also has some controversial/outdated info, like:
         | 
         | - A migraine is a normal headache, but worse
         | 
         | - Don't take triptans -- get off them if you're on them
         | 
         | - Migraines are vascular.
         | 
         | Not saying it's wrong, but it's definitely controversial. I
         | have no idea about the author's views on CGRP blockers, since
         | the book considerably predates them.
         | 
         | I've never tried hard enough to quit caffeine. I'd like to give
         | it a go. I typically feel better migraine-wise when I'm
         | drinking 1 cup daily than when I'm drinking 2-3. But
         | confounding variables etc etc etc.
        
       | internet_points wrote:
       | Some anecdata on prevention experiences:
       | 
       | * metaprolol (pulse-slowing beta-blocker): fewer attacks per
       | month, "dampened" attacks, bad side effects (fatigue, energy
       | loss, dark moods)
       | 
       | * magnesium supplements: no noticable effect (they say it might
       | have an effect if you happen to get too little through your food)
       | 
       | * vitamin B: no noticable effect
       | 
       | * simvastatin (cholesterol lowering medicine): some fewer attacks
       | per month, but attacks when they come seem full strength
       | 
       | * candesartan (also a blood pressure medicine): much fewer
       | attacks per month, "dampened" attacks, very few side effects,
       | current "winner"
       | 
       | (CGRP's are expensive, haven't tried.)
       | 
       | For stopping attacks, triptanes work well.
        
       | bfcapell wrote:
       | Anecdotal, but: I know someone with relevant migraine problems
       | did a log of everything she was eating or doing, searching for
       | possible triggers. After a few weeks there were a couple of
       | suspects: glutamate, chocolate, and also some legumes. Removing
       | these worked and reduced greatly the amount and extent of the
       | problem. Currently legumes is ok sometimes, but consuming one of
       | the first two is almost a guaranteed episode.
        
       | qweiop wrote:
       | I don't love Huberman, but his episode on headaches/migraines was
       | very informative. There was a lot of helpful tips for those
       | suffering.
        
       | adaptbrian wrote:
       | To hell with the drugs that they throw at you for headaches. It's
       | your diet, lifestyle and poor sleep that's drives this bus.
       | 
       | I'll save you 10 years of my suffering and the awful side effects
       | induced from the cocktail of drugs in this article and say I've
       | reversed cluster headaches and can now tell when anything is not
       | good for my body goes into it.
       | 
       | I did an elimination diet, I skip breakfast usually, and did 1
       | successful session of hyperbaric oxyegen treatment and it's
       | completely changed my life.
       | 
       | Ive been able to continue ketosis periodically and am adding
       | foods back now 1 by 1 to see what induces pain and believe it or
       | not your body will tell you.
       | 
       | My latest revelation was legumes which tricks you, high in carb
       | item that apparently is a different type of carb that doesn't
       | digest in the bottom of your gut like other carbs. (1)
       | 
       | This list of positive side effects can only seen as a miracle to
       | me from being on the edge of survival (my clusters were headed
       | towards a manic state)
       | 
       | -I don't get down and cynical at all like I used to -my daily
       | energy is a magnitude of about 5x stronger -confidence and
       | positivity are the first reactions i have now so it's greatly
       | uplifted everyone around me - there is a level of even keel
       | rationality that I have now that I've never ever had - just alot
       | more calmer overall and easier to get the busy mind not to
       | overworry
       | 
       | I've tried many drugs and techniques but everything felt like a
       | bandaid on the problem and not actually addressing it
       | 
       | Big and large psychedelic doses, triptans, cgrp, mood
       | stabilizers, steroids. If they had it i tried it.
       | 
       | It took about 1 month of major diet changes to start feeling
       | better. A year in now and the two things that feel the worst for
       | setting off mild nero inflamation are 1-not getting good sleep
       | and 2-eating highly processed foods
       | 
       | Your mileage may vary, everyone reacts to food differently.
       | 
       | 1 -
       | https://www.frontiersin.org/journals/nutrition/articles/10.3...
        
         | outime wrote:
         | As someone who has healed from some weird conditions by doing
         | what you suggest (specially diet), I would be cautious about
         | implying that everyone else is on the same path. Some people
         | may have excellent diets and sleep schedules but still suffer
         | from migraines or other debilitating conditions.
         | 
         | While I agree that lifestyle factors are often overlooked,
         | especially in the West where we tend to medicalize every
         | symptom, sometimes the root cause of the issue remains unknown.
         | Suggesting that it's always due to something like not following
         | a proper diet can be harmful.
        
           | takomako wrote:
           | Exactly.
           | 
           | I run or cycle daily and do small triathlons / half marathons
           | in the summer. I'm mostly vegetarian. I weigh 155 lbs and I'm
           | 5'11". I sleep fine.
           | 
           | I get random severe migraines 2-3 times a year.
           | 
           | I discovered sumatriptan. It stops the migraine almost
           | instantly when i sense one coming on (my vision starts to
           | "fuzz out").
           | 
           | Before this I would lose a day recovering in a dark room
           | lying down. I was scared whenever I backpacked or went on
           | long trips that I would have a migraine at the wrong time.
           | Sumatriptan freed me from this.
           | 
           | I'm glad OP found a cure that works for them but everyone is
           | different.
        
           | ianburrell wrote:
           | Another factor is that there are bunch of foods that are
           | common migraine triggers. It is possible that he cut out his
           | triggers with a limited diet.
           | 
           | For me, triggers include alcohol, chocolate, processed meats,
           | fermented and pickled food, and hops.
        
       | amelius wrote:
       | I had migraines with aura as a child from 12 to 16 years old. But
       | then I got bruxism and the migraines went away. Traded one
       | problem for another, I guess.
        
       | jncfhnb wrote:
       | I get migraines with aura prior to storms
       | 
       | I'll be damned if they're not the result of some sort of swelling
       | or inflammation of capillaries or the optic never or something. I
       | can feel it in such clear detail.
        
       | dghughes wrote:
       | I recall about 10 or 15 years ago at work in the lunchroom it was
       | me and maybe six younger people. Me age 40 them about age 20 six
       | all said they have migraines I didn't, didn't know anyone who
       | did. It seemed odd so many claimed to have migraines. I assumed
       | they meant a bad headache not actual migraines but were using the
       | term migraine to mean a bad headache.
        
         | assimpleaspossi wrote:
         | Just a note to say I noticed this, too.
         | 
         | Kids these days.
        
       | auc wrote:
       | Our understanding of migraines seems to be increasing
       | exponentially
        
       | atlanta90210 wrote:
       | Stop all forms of coffee for 3 months you will be amazed at how
       | few you get after that. Tea is fine, just no coffee. Life changer
       | for me.
        
       | mentos wrote:
       | Haven't had a migraine with visual auras since giving up alcohol
       | fwiw. My friend's dad specializes in headache treatment he said
       | majority is dehydration which would add up for my case but
       | interesting to see a comment below where someone gets them from
       | too much water so I guess having the correct water balance is
       | key.
        
       | savikko wrote:
       | Just an anecdote, but very close person of mine was diagnosed
       | with migraine when she was 12 yo old so.
       | 
       | Last year, being 40+ years old, suffering from weekly/daily pain
       | events, she found out that diagnose was wrong (one doctor just
       | asked that have you ever thought that this probably isn't
       | migraine) and correct diagnose was Horton / cluster headache.
       | 
       | Eating migraine meds (lots of different ones) for several years
       | were helping, but probably only due placebo effect.
       | 
       | Now, the medicine for headache attacks is simple: breathing pure
       | oxygen for 15 minutes.
       | 
       | After last attack (1.5 year ago, stopped almost immediately
       | breathing oxygen) there has not been any headaches.
       | 
       | Usually, it would not been nice to get diagnose for cluster
       | headache, but on this case it was kind of life saver.
       | 
       | Still, just an anecdote.
        
       | ghelmer wrote:
       | I have experienced migraines since my teens, usually starting
       | with annoying visual artifacts, facial numbness, difficulty
       | speaking, and progressing to intense pain. The worst of them
       | would also cause auditory discomfort. In my 20s, I could reliably
       | trigger a migraine by doing something intensely physical (like
       | playing basketball with friends) and drinking lots of cold water
       | or taking a cool shower. Since then, it's been harder to
       | determine a cause other than stress. About 15 years ago, work was
       | really stressful and I had numerous migraines in a four-month
       | period. Once I even got a demerol IM shot, which seemed like much
       | ado about nothing -- I was hoping for great relief, but it didn't
       | seem to do much. Now in my 50s, I only get about one a year, and
       | it's pretty mild.
        
       | qazwse_ wrote:
       | I always feel a bit weird when reading migraine threads on the
       | internet, because mine seem so much milder, but it's still
       | debilitating. I remember first noticing the migraines in grade
       | when I was 16, but it took me years before realizing they were
       | migraines. I thought that most people had pain like I did, and
       | just powered through with some Advil/Tylenol.
       | 
       | My migraines follow a very regular schedule. I wake up and just
       | know that I will have a migraine. It's like a nagging thought.
       | Worse after days of poor/little sleep, or days where the
       | temperature changes dramatically, or if there is a big storm. At
       | around 14:00 the pain grows in intensity, I feel nauseous and
       | uncoordinated, very sensitive to light. Lying in a dark room and
       | listening to a podcast/YouTube video is the best way to get
       | through this period, I can get to the edge of sleep and it makes
       | it easier. At around 20:00 the pain has usually mostly subsided,
       | and by 22:00 I'm pain free but exhausted.
       | 
       | I tried a few prescription medications after talking with a
       | doctor, but they didn't have much of an effect, so I just
       | accepted that once every 1/2 weeks I would have to deal with it.
       | Whenever I would read about migraines online, I would feel
       | relieved, because mine seemed so much more mild. No aura, the
       | pain is usually gone within a day, and if I needed to be out and
       | about I could manage, even though it was painful.
       | 
       | About 5 years ago an ex-partner offered me a Bufferin (Aspirin
       | mix), and right away it helped with the symptoms. Read into it
       | and saw a study that suggested some people respond well to high-
       | doses of aspirin and caffeine for migraine relief. It worked
       | exceptionally well for me. 9/10 migraines knocked out
       | immediately, with the rest being substantially reduced in length
       | and intensity. I get maybe 1 migraine a year now that is truly
       | bad.
       | 
       | Recently talked to a new doctor who prescribed me propanolol (he
       | was afraid about the high dose of aspirin on my stomach), and
       | it's been just as good.
       | 
       | I just feel fortunate to have easy access to migraine relief, and
       | I hope that others are able to find something that works for them
       | as well.
        
         | asveikau wrote:
         | I think my biggest trigger is changing weather. I usually
         | attribute this to changing light levels but I'm not sure.
         | 
         | I spent about 30 years getting migraines before I realized that
         | wearing sunglasses helps my light sensitivity. It seems like
         | that'd be a fairly intuitive thing to have tried, but somehow I
         | never did.
        
       | corry wrote:
       | I get migraines about 6 - 8 times a year, complete with visual
       | aura and very occasionally speech aphasia. I tracked them in a
       | spreadsheet for years so have a rough idea of triggers but it's
       | proven fairly bad at predicting.
       | 
       | I've tried many drugs to combat them, but there is one thing that
       | helps me short-circuit it 99% of the time is a high amount of
       | caffeine. It's not perfect -- I liken it to side-stepping a
       | train; you get missed by the train itself but still get thrown
       | off by the wind and noise, still fall hard on the ground, still
       | get bruised but not hurt as badly -- but it works well enough, so
       | as soon as I get the visual aura, I slam back a strong coffee and
       | know that it'll work. Why? No idea, perhaps the pressure in the
       | brain's blood vessels are affected?
       | 
       | What I don't see as often discussed is the subtle changes in
       | consciousness that accompany migraines.
       | 
       | For me, in the pre phase (12 hours or less before the true
       | onset), the first sign that I'm heading towards one is a sudden
       | immediate bias towards pessimism with a kind of resignedness too
       | (which is quite unlike my normal states of mind). That's often my
       | first clue. It's like the storm clouds are gathering on the
       | horizon and all light and colour is drained from my life.
       | 
       | Then, the visual aura hits. Now I know what's happening with
       | certainty and I hit my caffeine prophylactic. The caffeine
       | stimulation combined with the first inklings of pain and
       | knowledge that you're about to go "into the shit" gives you quite
       | a fight/flight feeling. You're at a bit of a loss as to what to
       | do, since you're amped up but there's nothing to do but wait it
       | out.
       | 
       | Then once the aura fades, you feel quite strange. I'll typically
       | go lie down at this stage. If the caffeine worked (which is like
       | 99% likely for me), I feel in a kind of haze but I'm not in deep
       | pain - just uncomfortable and mentally quite scattered, though
       | I'm no longer pessimistic about the future. In fact, it's like
       | time collapses, and I'm forced to be in the moment. It makes me
       | feel sick to try to think about the past or future - it all feels
       | like a huge burden to try to internalize those states of time. I
       | just try to focus on my body and how I'm feeling. It's almost
       | like a meditative state. I can't sleep due to the caffeine but I
       | try to rest and keep my mind clear.
       | 
       | At some point I'll realize that I'm mostly through it, and can
       | get up and move around and generally kind of resume my day. But
       | it feels like a hangover of sorts. Everything is hazy. Thinking
       | is difficult. Very sensitive to light and noise.
       | 
       | Then, surprisingly, the next day I'll feel mentally GREAT like my
       | mind was cleaned.
       | 
       | Which brings me to the most interesting part of all this for me -
       | the migraine has a lot of similarities to a psychedelic trip.
       | There's a come-up that's distressing, a plateau where one is
       | forced to be in-the-moment, a depletion afterwards, and the next
       | day onwards a feeling that things are cleaner and better ordered
       | than before, like your mind and spirit has been defragged.
       | 
       | Perhaps both the migraine and the psychedelics are stressors or
       | some kind of release valve on your brain.
       | 
       | One wonders if there's increased brain plasticity post-migraine
       | like with psychedelics.
        
       | Agentus wrote:
       | My migraines have been with me for ten years now and they have
       | slowly evolved their symptoms and triggers. Started off more as
       | typical migraines that happened every other day, though i had
       | head issues everyday. it later evolved to neck pain, jaw pain,
       | temple numbness, throbbing headaches, inability to think or
       | process things. lots of cooccurring head symptoms include feeling
       | of blood pulsing.
       | 
       | visited countless medical people, most offered no real solutions
       | or relief. only consistent insight, temperature baths for my head
       | reduced at least tthe superficial symptoms but not the cognitive
       | symptoms, the superficial symptoms seemed to be aggravated by
       | sleep. the cognitive symptoms correlated to hard processing and
       | thinking, straining the brain. but the detriment to my life made
       | it hard balancing work and responsibilities. worse is the
       | symptoms are debilitating at times and invisible, good luck
       | getting sympathy or understanding from other people with that
       | being the case. im homeless cause its better to not have
       | repsonsibilities and control how much i strain my brain than deal
       | with the headaches daily and worse.
       | 
       | this whole ordeal makes you realize how limited the medical
       | profession is.
        
       | smeeger wrote:
       | i have been getting bad migraines for as long as i can remember.
       | bad enough to vomit when i was a kid. nothing ever helped except
       | when i took a healthy dose of lsd in highschool and they stopped
       | completely for five years or so. i had been getting them around
       | once every two months before that. then they came back in college
       | and slowly got worse until i was having basically one long
       | migraine for up to a week at a time. then i started taking
       | nurtech. it helped a lot but only worked half the time -- and
       | when it did work i could still feel my body reeling from it but
       | without pain. here is something curious: i noticed that nurtech
       | would put me into an extremely good mood... almost to the point
       | of being a different person. without any euphoria or
       | intoxication. specifically, i noticed that i was much more open
       | emotionally, much more personable and friendly. more open to
       | letting people in. and thats when i really started to have a new
       | perspective on just how much this disease had robbed from me. i
       | cant even imagine how awesome it would have been to not be
       | interrupted by these migraines, to not have to feel the throbbing
       | pain, and maybe the whole trajectory of my life would have been
       | different if i had been a little kinder and likable which, if im
       | being honest, i was kind of known for not being. i dont really
       | take nurtech anymore because i have found that hard physical
       | work, sunlight, reducing total calories and cardiovascular
       | exercise basically put them into remission. and im afraid of what
       | nurtech might do to me long-term after seeing how profoundly it
       | alters my personality. based on everything i know, i think its
       | safe to say that migraines are a metabolic disorder. neurons
       | become overexcited due to metabolic dysfunction which then causes
       | a depolarization cascade that sweeps across other regions of the
       | brain. thats why keto helps so much. i wonder if ozempic has a
       | beneficial impact on migraine?
        
       | diob wrote:
       | I used to think everyone got migraines everyday, then I got
       | diagnosed with sleep apnea. Hardly a thing for me anymore now
       | that I use cpap, but I dealt with them constantly until my senior
       | year in college.
       | 
       | But it reminds me how we only really know our own reality, and
       | it's easy to assume our experience as "normal".
        
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