[HN Gopher] Richard A. Cash, who saved millions from dehydration...
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       Richard A. Cash, who saved millions from dehydration, has died
        
       Author : impish9208
       Score  : 151 points
       Date   : 2024-11-07 15:54 UTC (7 hours ago)
        
 (HTM) web link (www.nytimes.com)
 (TXT) w3m dump (www.nytimes.com)
        
       | joecool1029 wrote:
       | https://archive.ph/wTJu9
        
       | kylehotchkiss wrote:
       | What a legacy to leave behind. RIP Mr. Cash, thank you for your
       | contributions to humanity. May many others follow in your
       | footsteps.
        
       | Scoundreller wrote:
       | Also mitigated many millions of hangovers, including my own.
       | 
       | Too bad the commercial nature of "sports drinks" have dialed up
       | the sugar and broke away from the clinical goal of rehydration.
        
         | paulpauper wrote:
         | they sell sugar free sports drinks
        
           | willcipriano wrote:
           | Gatorade has a entire line of drinks for different purposes.
           | Zero is what OP is looking for: https://performancepartner.ga
           | torade.com/content/products/hyd...
           | 
           | The normal one is for high powered endurance activities and
           | contains some carbs (sugar) to help fuel you through them.
           | 
           | They have one with even more carbs, sodium and potassium for
           | people running marathons.
           | 
           | The last two on that chart aren't a good choice for someone
           | who isn't active. Stick to the first two for that.
        
             | bigfatfrock wrote:
             | Propel and Zero (the first options) both contain sucralose,
             | aka Splenda - I'd prefer to just drink salt water
             | personally, or take the hit on a tablespoon of sugar mixed
             | in and walk it off.
        
               | willcipriano wrote:
               | The majority of Americans are overweight, as far as the
               | science shows artificial sweeteners are the best choice
               | for them vs full calorie.
               | 
               | If you look up the evidence for the downsides of
               | artificial sweeteners anything that finds one is
               | generally an observational study. So for example, the
               | claim that they cause obesity is backed by the
               | observation that obese people consume it in greater
               | amounts than people who are not obese. That's like
               | standing in front of a hospital and noticing everyone
               | with a broken leg is on crutches and coming to the
               | conclusion that crutches are the problem. Double blinded,
               | placebo controlled studies don't find this effect. The
               | best evidence we have indicates they are safer than the
               | obesity that full calorie sweeteners cause in most
               | people.
        
               | swatcoder wrote:
               | > The majority of Americans are overweight, as far as the
               | science shows artificial sweeteners are the best choice
               | for them vs full calorie.
               | 
               | This is a false choice and has nothing to do with the
               | above commenter's preferences.
               | 
               | Many people just desperately long for convenient
               | foods/drinks that aren't so sweet in the first place and
               | feel frustrated that the largest brands don't want to
               | bother with them.
        
               | xtracto wrote:
               | I maje my own electrolyte drink with water, spoonful of
               | sugar and spoonful of "low sodium" salt: they add
               | potassium to those, which completes the electrolyte menu.
               | 
               | Sometimes I add a dash of lime
               | 
               | Veeeey low cost and great. And you can pre-mix it in a
               | zip lock bag to have it always available. And add some
               | orange flavour kool-aid powder if you need flavour.
               | 
               | Commercial Rehydration drinks are overpriced and
               | overhyped IMHO
        
               | foxyv wrote:
               | I like pickle juice. The vinegar helps the salt go down
               | better.
        
             | ajb wrote:
             | Yeah, although worth noting that glucose is useful to
             | promote absorption of the electrolytes, you may not need it
             | in a sports drink but it's an integral part of the diarrhea
             | med.
        
           | thinkingtoilet wrote:
           | That's the point. A little sugar is good. Too much sugar is
           | bad. No suger is not as good. It's very modern to have two
           | options, one with waaay too much sugar and one with zero
           | sugar (or some sugar replacement).
        
         | soperj wrote:
         | You can always go with a Roman sports drink. Salt, water and
         | some red wine vinegar (apple cider vinegar works too)
        
         | Reason077 wrote:
         | > _" Too bad the commercial nature of "sports drinks" have
         | dialed up the sugar and broke away from the clinical goal of
         | rehydration."_
         | 
         | The ones that come as tablets which dissolve in water give you
         | the electrolytes without the sugar. Less packaging waste, too.
         | SIS (Science In Sport) is good, and other brands are available.
        
           | Scoundreller wrote:
           | You want _some_ sugar, but putting even more than necessary
           | sells better.
           | 
           | Sugar, like salt, is a solute and will impair water
           | absorption.
        
         | tmoertel wrote:
         | You can always make your own sports drink, starting with the
         | recipe from the World Health Organization:
         | 
         | https://www.who.int/publications/i/item/WHO-FCH-CAH-06.1
         | 
         | Just 4 ingredients:
         | 
         | Glucose, anhydrous (dextrose)
         | 
         | Sodium chloride (salt)
         | 
         | Potassium chloride
         | 
         | Trisodium citrate, dihydrate
         | 
         | Of course, the batch size of 75 kg may not be the most
         | convenient for home use, but it's easy to scale down.
        
         | spondylosaurus wrote:
         | Generic Pedialyte is great for hangovers and migraines--way
         | less sugar. You can even get the individual powder packets
         | instead of having to buy a huge jug of liquid.
        
         | MisterTea wrote:
         | There's a bananna bag mix you put in water. Comes in packets.
         | Quite invigorating.
        
       | greentxt wrote:
       | "We're enamored by high technology," he said at the Council on
       | Foreign Relations. "And we're not in love with low-tech. Low-tech
       | is always seen in our eyes as second-class. Why would you do
       | this, when you could do that? And I would argue just the
       | opposite."
       | 
       | Noteworthy that others tried to gatekeep thier low tech approach
       | and experimental efforts. So much "perfection, enemy of the good"
       | in expert circles.
        
       | cyberax wrote:
       | People tried oral rehydration before with isotonic solutions,
       | even going as far as matching the concentration of minerals in
       | plasma. It didn't work well for cholera.
       | 
       | The amazing discovery was that just a bit of glucose made the
       | world of difference.
        
       | andrewinardeer wrote:
       | On a side note, his Wikipedia page has one of the worst, low res
       | leading photographs for a topic I've ever encountered on that
       | site. Surely a man of his stature deserves better?
        
       | WarOnPrivacy wrote:
       | This caught my attention. From the article:
       | Other doctors and nurses found their experiment [drinking water
       | w/ sugar+salt] bizarre and tried to stop them.
       | 
       | To me that seemed like professionals clinging to orthodoxy for
       | orthodoxy's sake. They forget that endless reevaluation is needed
       | for a practice to remain 'best'.
       | 
       | And maybe it was that. But I also found this talk from Dr Cash;
       | he gives other examples of resistance (along with their causes).
       | Whereas, in one country I went to, Jamaica, I was puzzled, even
       | though I was working at that time for PAHO, that there was
       | terrific opposition. It seemed that they wouldn't cooperate with
       | anything. Even they wouldn't give my assistant a bed in the
       | residence quarters.               So I found out gradually--I was
       | investigating this--and I found out several things. One is, the
       | head of the hospital was so skeptical about this working that he
       | had made a hundred dollar bet with his residents that it would
       | fail. So obviously there was an incentive for it to fail.
       | (Laughs.)               Secondly, the head of hospital stores, I
       | found out, was making a lot of money on kickbacks from the IV
       | company. So he had no interest in terms of resource flow of
       | substituting oral for IV.
       | 
       | ref: https://www.cfr.org/event/simple-solution-saved-fifty-
       | four-m...
        
         | wetpaws wrote:
         | >people clinging to orthodoxy for orthodoxy's sake.
         | 
         | Always been like this. Even something as simple as making them
         | wash hands was a pain.
        
         | WorkerBee28474 wrote:
         | > To me that seemed like professionals clinging to orthodoxy
         | for orthodoxy's sake.
         | 
         | There's much I don't know about medicine in Bangladesh, but I'm
         | guessing doctors think it's unethical to treat patients with
         | anything other than the best accepted standard of care, unless
         | engaging in an experiment for which the risk and benefits can
         | be described and there exists a reason to believe the benefits
         | outweigh the risks. I suspect that was not communicated well by
         | the experimenters.
        
       | encoderer wrote:
       | Reminds me of Norman Borlaug.
       | 
       | Talk about leaving a dent.
        
         | textlapse wrote:
         | People are so against GMOs without realizing how many millions
         | of lives GMO'ed wheat and rice saved in India and elsewhere.
         | 
         | Both (Norman Borlaug and Dr Cash) go to show that modern and
         | traditional medicines can be carefully manipulated in amazing
         | ways to save millions of lives.
        
           | marcosdumay wrote:
           | If you press them, you'll discover most people are against
           | Monsanto and only a tiny minority actually cares about GMO.
        
         | alecco wrote:
         | But most people worship vapid celebrities. As a species, we
         | need some more evolving.
        
       | throw0101a wrote:
       | Regarding the dehydration work see:
       | 
       | > _Oral rehydration therapy (ORT) is a type of fluid replacement
       | used to prevent and treat dehydration, especially due to
       | diarrhea.[1] It involves drinking water with modest amounts of
       | sugar and salts, specifically sodium and potassium.[1] Oral
       | rehydration therapy can also be given by a nasogastric tube.[1]
       | Therapy can include the use of zinc supplements to reduce the
       | duration of diarrhea in infants and children under the age of
       | 5.[1] Use of oral rehydration therapy has been estimated to
       | decrease the risk of death from diarrhea by up to 93%.[2]_
       | 
       | * https://en.wikipedia.org/wiki/Oral_rehydration_therapy
        
         | emmelaich wrote:
         | ORT seems to have been developed in the mid 1960s, around the
         | same time as Gatorade.
         | 
         | I wonder how much one informed the other.
        
           | throw0101d wrote:
           | * https://en.wikipedia.org/wiki/Gatorade#Origin
        
       | zusammen wrote:
       | I met him in the late 1970s. I was too young then to understand
       | his work at the time, but he was one of the few famous people I
       | have met who genuinely cared about other people. He was as one of
       | the good ones. RIP.
        
       | CalChris wrote:
       | So I had cholera.
       | 
       | I was in a cholera study at the University of Maryland for a
       | week. Read a lot of sci fi, played ping pong and drank fluids
       | with electrolytes. There is a first phase which is uncomfortable
       | but otherwise, as the docs said, cholera is a piece of cake if
       | treated with hydration.
        
         | throwaway4220 wrote:
         | Whoa! I didn't know you could do such studies on humans this
         | day and age. Were you compensated handsomely?
        
           | plorkyeran wrote:
           | https://eukaryotewritesblog.com/2024/10/21/i-got-
           | dysentery-s... is a writeup of a similar trial that hit HN
           | recently. That person got $4000 for 10 days.
        
           | foxyv wrote:
           | Yup, they are called Human Challenge Studies. Compensation is
           | typically modest. Most participants are students at
           | universities.
           | 
           | https://en.wikipedia.org/wiki/Human_challenge_study
        
       | nelblu wrote:
       | for a few moments I was thinking "saved millions of dollars from
       | dehydration". The title could be clearer if it said "saved
       | millions of people from dehydration".
        
         | joemi wrote:
         | I thought the same thing before clicking on it.
        
         | ricksunny wrote:
         | I wonder if headline writers these days generate several
         | permutations of a headline via GPT, and have some way of A|B
         | testing the early readers to figure out which one generates the
         | most clicks (especially due to people clicking through to
         | satiate curiosity of a freshly quizzical headline from what
         | would otherwise have been an at-a-glance comprehensible one
         | that would fail to elicit the all-lifegiving click.)
        
       | acyou wrote:
       | I also have a feeling that the pH of rehydration drinks should be
       | low (acidic). To an extent, my body knows pretty well what's good
       | for it. The salt+water tastes terrible, add a little acid and
       | it's delicious. Maybe it takes a little load off of the digestive
       | system by providing the acid that would otherwise need to be
       | generated.
        
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       (page generated 2024-11-07 23:01 UTC)