[HN Gopher] The Cellular Secret to Resisting the Pressure of the...
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       The Cellular Secret to Resisting the Pressure of the Deep Sea
        
       Author : Brajeshwar
       Score  : 78 points
       Date   : 2024-09-11 16:00 UTC (3 days ago)
        
 (HTM) web link (www.quantamagazine.org)
 (TXT) w3m dump (www.quantamagazine.org)
        
       | andrewflnr wrote:
       | > Archaea lipids behave differently than those found in bacteria
       | and eukaryotes
       | 
       | That's a hell of a thing to drop with no further explanation. I
       | thought eukaryotes were supposed to have evolved from basically
       | archaea, or at least very archaea-like ancestors. How do
       | eukaryotes end up sharing chemistry with bacteria but not
       | archaea?
        
         | Sniffnoy wrote:
         | Bacterial genes migrating from the mitochondria to the nucleus
         | -- or at least, that's the theory I read in "The Vital
         | Question" by Nick Lane.
        
         | unddoch wrote:
         | It's one of the problems with the 'current' model of
         | Eukaryogenesis. Eugene Koonin has recently suggested an
         | interesting two stage model based also on shared virus
         | phylogenies: https://www.nature.com/articles/s41564-023-01378-y
        
         | adrian_b wrote:
         | The eukaryotes share most of their metabolic paths with
         | bacteria instead of archaea, not only their membrane
         | composition.
         | 
         | Because all the known eukaryotes have their origin after the
         | symbiosis with the bacteria that have become mitochondria and
         | most of the genome of the mitochondria has been moved to the
         | nucleus, one possibility is that all the bacterial
         | characteristics of the eukaryotes come from the ancestor of
         | mitochondria.
         | 
         | There are alternative hypotheses, e.g. that there have been a
         | few other symbiosis events with some bacteria, before the
         | symbiosis with the ancestor of mitochondria, so some of the
         | bacterial characteristics are inherited from different
         | bacteria.
         | 
         | A possibility is that some of the differences between archaea
         | and bacteria have arisen after the divergence between archaea
         | and eukaryotes, so the bacterial characteristics of the
         | eukaryotes would be primitive. However this supposition has
         | become more unlikely during recent years, because some evidence
         | has accumulated that appears to support a closer relationship
         | between eukaryotes and some of the archaea than with the other
         | archaea, in which case all characteristics shared by all
         | archaea would predate the divergence with the eukaryotes.
        
         | kleton wrote:
         | Archae have ether linkages in their lipids, bacteria and
         | eukaryotes have glycerol esters.
        
       | blackeyeblitzar wrote:
       | So is the idea that the behavior of the deep sea membrane, which
       | is like a compressed spring, could be mimicked in artificial
       | materials to resist high pressures?
        
       | noisy_boy wrote:
       | Very interesting - it is as if the healthy membrane shape is the
       | target bytecode to which the varying "source" shapes in varying
       | categories of jellies converge to under varying
       | temperature/pressure conditions in order to live.
        
       | jcynix wrote:
       | Interesting small creatures, which (as a side note) can have
       | enormous ecological impacts as the Wikipedia article mentions:
       | 
       | "On the other hand, in the late 1980s the Western Atlantic
       | ctenophore Mnemiopsis leidyi was accidentally introduced into the
       | Black Sea and Sea of Azov via the ballast tanks of ships, and has
       | been blamed for causing sharp drops in fish catches by eating
       | both fish larvae and small crustaceans that would otherwise feed
       | the adult fish."
       | 
       | https://en.wikipedia.org/wiki/Ctenophora
        
         | _Microft wrote:
         | What would be a solution to carrying lifeforms elsewhere in the
         | ballast tanks? Turning the water over regularily to reduce the
         | distances that these creatures can travel aboard?
        
       | littlestymaar wrote:
       | I don't really understand what's the "problem" with high pressure
       | for living things: they are full of water at the same pressure as
       | the surrounding water so there's no risk to be _crushed_ , so
       | it's not clear to me what "resisting the high pressure" means.
        
         | bondarchuk wrote:
         | It seems to be more about the different chemical properties of
         | proteins under pressure, rather than structural problems that
         | come with pressure difference. Just like e.g. water has a
         | higher boiling point when pressurized, all kinds of chemical
         | processes are different under pressure.
        
         | sega_sai wrote:
         | They talk about it in the article. The last figure shows what
         | happens to the normal membrane at high pressures, it becomes
         | too stiff/compressed and therefore cannot function (i.e. let
         | things through etc)
        
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