[HN Gopher] Four Thieves Vinegar Collective - Harm Reduction for...
       ___________________________________________________________________
        
       Four Thieves Vinegar Collective - Harm Reduction for the Living
        
       Author : Beijinger
       Score  : 143 points
       Date   : 2024-09-07 14:19 UTC (8 hours ago)
        
 (HTM) web link (fourthievesvinegar.org)
 (TXT) w3m dump (fourthievesvinegar.org)
        
       | Beijinger wrote:
       | This is FYI and NOT an endorsement!
        
         | samtho wrote:
         | I am legitimately unsure why you felt the need to make this
         | comment.
         | 
         | If you were uncomfortable posting this it here because you
         | think that someone else might take it an endorsement, then why
         | did you post it? People post things they find interesting and
         | disagree with all the time. What are you afraid of?
        
           | Beijinger wrote:
           | This is hackernews. I had problems in the past that people
           | mistake this for an endorsement.
        
       | zero-sharp wrote:
       | Healthcare in the US is terrible, sure. And making medicine more
       | accessible is a great thing. But I feel like the term "right to
       | repair" is being hijacked here. A manufacturer that creates a
       | piece of technology can theoretically publish repair instructions
       | and provide parts (at a reasonable cost). This is different than
       | the issue of accessibility in the drug space?
       | 
       | Maybe I'm making a fuss over nothing, but it just stood out to
       | me.
        
         | jstanley wrote:
         | Why is it different?
        
           | MobiusHorizons wrote:
           | Who is the manufacturer of the item to be repaired? How is
           | the manufacturer preventing repair? What design decisions
           | artificially limit repair to parties other than the
           | manufacturer? How does the manufacturer use existing
           | regulation (eg DMCA or copyright) to prevent repair or access
           | to information necessary for repair.
           | 
           | All of these questions make sense for right to repair, and
           | are mostly nonsensical in this case, since drug companies
           | don't manufacture bodies.
        
             | fnordpiglet wrote:
             | Essentially the instructions and tools to repair your own
             | body are restricted and only accessible to those who can
             | afford to pay for the health care systems processes. Have
             | an obvious infection? Spend a ton of money going to a
             | doctor to get a prescription to give to a pharmacy to
             | dispense at highly marked up substance that's easy to
             | manufacturer at a tiny unit cost. You had no right to cure
             | your own infection. You had to pay dozens of middle men for
             | something straight forward.
             | 
             | I'd note that in most of the world you would just go buy
             | the antibiotics directly from a pharmacy for almost
             | nothing.
             | 
             | Now - I'm not saying self medicating with antibiotics is
             | either good for you or the world, I'm saying at least in
             | the US, you don't have that right.
        
               | mnau wrote:
               | Please stop trying to co-opt established term for your
               | pet cause.
        
               | MobiusHorizons wrote:
               | Believe me, I agree that this is a problem. I have lived
               | in other countries, and have seen how broken certain
               | aspects of US healthcare are especially with regards to
               | cost. These problems are just totally different than
               | "right to repair" if in no other way than that the legal
               | solutions would be completely different. For example any
               | right to repair legislation would have no bearing on drug
               | prices.
        
               | grayhatter wrote:
               | If it was easier to get the federal approval required to
               | produce medications wouldn't that lower the cost of
               | producing those medications?
        
               | wpietri wrote:
               | That's some very careful cherry picking you've done there
               | with your example. Maybe next time you're in a pharmacy
               | you'll take a look at the aisles and aisles of over-the-
               | counter medicines and devices available and do some
               | thinking about your belief that "instructions and tools
               | to repair your own body are restricted and only
               | accessible to those who can afford to pay for the health
               | care systems processes".
        
               | grayhatter wrote:
               | I don't understand what you're trying to say, because
               | there are low potency options that are available over the
               | counter, that means the most effective treatments are
               | correctly access restricted?
               | 
               | Can you name an over the counter antibiotic that
               | successfully treats a staph infection? or strep throat?
               | or sinus infection?
        
               | wpietri wrote:
               | I am saying his cherry-picking of antibiotics
               | specifically while he make dramatic claims is ignoring
               | all of the over-the-counter mediation sold in the
               | pharmacy. There are quite a lot of illnesses one can
               | treat without ever talking to a doctor. I don't know what
               | other people's ratios are, but my use of OTC medication
               | and "tools" is maybe 10x more frequent than stuff that's
               | gatekept by a doctor.
               | 
               | He is also ignoring the reasons that we have ended up
               | with this system. Some of them are kind of dumb, but some
               | of them are about valid problems. That's very different
               | than what "right to repair" is fighting, which is mostly
               | about exploitative companies trying to maximize revenue
               | at the expense of their customers.
               | 
               | [Edit: misunderstood who replied; correcting pronouns]
        
               | pennybanks wrote:
               | its kind of wild your trying to create sides in this fake
               | debate and then somehow trying to side with repairing
               | electronics over peoples health?
               | 
               | why though lol, do you hate sick people? or just have no
               | empathy for people in general?
               | 
               | who cares about technicality and semantics and whois
               | using whos catch phrase better... we should be discussing
               | an issue far more important, like so much more important
               | its funny to even compare. then being able to switch your
               | iphone battery out.
        
               | wpietri wrote:
               | I have no idea why you take any of that away from what I
               | wrote. I am in favor of both repairing electronics and
               | people's health. I'm just saying that the right-to-repair
               | framing for medical stuff is not a great way to look at
               | it.
        
             | grayhatter wrote:
             | > Who is the manufacturer of the item to be repaired?
             | 
             | This isn't important to the point, but for the sake of
             | argument; lets say society is the manufacturer.
             | 
             | > How is the manufacturer preventing repair?
             | 
             | Local legal regulatory groups that deem some method of
             | fixing (treating) some defect (health condition) too
             | dangerous to allow.
             | 
             | > What design decisions artificially limit repair to
             | parties other than the manufacturer?
             | 
             | Company (local agency) wont allow my neighborhood repair
             | shop to buy (or make) replacement screens (medications) or
             | batteries (contact lenses).
             | 
             | > How does the manufacturer use existing regulation (eg
             | DMCA or copyright) to prevent repair or access to
             | information necessary for repair.
             | 
             | Existing is a stretch considering the age of the DMCA. But
             | drug scheduling in the US is an equivalent and equally
             | nonsensical application of logic for example.
             | 
             | > All of these questions make sense for right to repair,
             | 
             | I know how to fix it, but because of laws and regulations
             | and decisions outside my control, I'm unable to apply that
             | knowledge.
             | 
             | > and are mostly nonsensical in this case, since drug
             | companies don't manufacture bodies.
             | 
             | The DMCA is your own example, and it's a law built and
             | advocated to enable control, and reduce supply
             | artificially.
             | 
             | There's definitely a point to be made and a discussion to
             | be had about the origins for control over health and
             | medical issues. I think permitting the sale of snake oil is
             | harmful to society, and we should prevent it so people
             | don't have to become experts in human biology to not get
             | conned. But treating chronic health conditions shouldn't be
             | as hard as it is.
             | 
             | The core of right to repair, is you shouldn't be allowed to
             | prevent me from, or make it and possibly difficult for me
             | to improve something I own and control. I think saying I
             | own and control my body and health is a fair assertion, so
             | the same argument applies; it's wrong to make accessing
             | repair options for my health as hard as it is if I'm
             | willing to try to fix it.
             | 
             | I'd say the same concepts behind right to repair apply more
             | so to the body because I can't just replace it.
        
             | samtho wrote:
             | In some ways, the gatekeeping of healthcare should be met
             | with more resistance than repair an item that someone else
             | made but you now own.
             | 
             | Your body is something that belongs to you, you technically
             | manufacture, yet you are legally forbidden from applying
             | known and often the most effective remedies to your own
             | body if you don't engage with a giant government-sanctioned
             | system that can charge you whatever they want.
             | 
             | To top it all off, the rules are not even consistent and
             | are motivated by reasons other than what is best for the
             | patient.
             | 
             | For example, taking more than the maximum dose of Tylenol
             | at can cause long-term or permanent liver damage. This is
             | still available over the counter with no restrictions
             | whatsoever.
             | 
             | On the other side, we can see that the DEA was created to
             | enforce drug policy (or rather racism and classism via drug
             | policy) which has the effect of making access difficult for
             | many people who are prescribed scheduled substances. Yet we
             | have a opiate crisis that managed to appear within this
             | draconian regulatory environment.
             | 
             | Then we have situations like the FDA which been aware of
             | the dangers of high sugar in diets, but the sugar
             | industry's dollars into "studies" managed to convince them
             | that "dietary fat" is the problem.
             | 
             | The "for your own good" argument only works if they
             | actually acted for our best interests, but time and time
             | again, it's shown to us that this is just a big game in
             | which we have no say in, yet we are all subjected to.
             | 
             | We should have the right, as an informed human, to
             | independently decide what we want to do to or put into our
             | body, just as we should have the right to choose what we
             | wish to do with our possessions.
        
               | mnau wrote:
               | > In some ways, the gatekeeping of healthcare should be
               | met with more resistance than repair an item that someone
               | else made but you now own.
               | 
               | That is never the case. Humans are very risk averse and
               | risk of broken product is infinitely smaller than risk of
               | screwing up with your health.
               | 
               | That's how we ended up with the straightjacket system.
               | Rachet goes only one way, there is a crisis (e.g.
               | thalidomide in 70s, snake oil salesmen and so on), we
               | rachet it up to ensure confidence.
               | 
               | The consequences of a single case of problem have a
               | decade long consequences. E.g. baby formula was
               | contamined in China (wiki "2008 Chinese milk scandal"),
               | 300k were sick, six children died. Baby formula is not
               | trusted even a decade and half later and imported stuff
               | is used.
        
         | MobiusHorizons wrote:
         | I agree this is a totally different thing. It definitely feels
         | like they are trying to make use of the feelings people have
         | about the right to repair movement for their own agenda. Some
         | might say co-opt, others riff off of. I can see that there are
         | some similarities, but power struggle and regulatory situations
         | are totally different.
        
         | kevmo wrote:
         | If you just make a post about healthcare in the USA being
         | awful, it's highly likely to be removed/booted off the front
         | page. Call it a "right to repair", though, and you're hitting
         | the sweet spot for HN.
        
         | AlbertCory wrote:
         | Exactly. They've taken a popular term and applied it where it
         | doesn't fit.
         | 
         | You may have a "right to repair" something you bought. You
         | didn't buy your body.
         | 
         | Drug safety is an old, old issue. We can argue about how it's
         | applied without dragging in popular phrases that don't apply.
        
           | pennybanks wrote:
           | i mean we could. but it seems like you wouldnt want that
           | since your brining it up yourself. seems very like a very
           | easy thing to ignore since it doesnt seem any malicious.
           | unless there are trademarks im not aware of.
        
       | blackeyeblitzar wrote:
       | Interesting concept. I love the idea of a right to repair for our
       | body.
        
       | ZunarJ5 wrote:
       | I just saw this writeup on them:
       | https://www.404media.co/email/63ca5568-c610-4489-9bfc-779180...
        
       | Apfel wrote:
       | Saw these guys talk at DEFCON this year, absolutely fantastic
       | presentation. It was so powerful and important that I'd actually
       | recommend watching it before pretty much everything else from the
       | con.
        
         | greyface- wrote:
         | Recording here: https://www.youtube.com/watch?v=5rQklSmI_F0
        
           | polishdude20 wrote:
           | I've watched a bunch of this. Does he mention where to get
           | the precursors to the medicines he's trying to make?
        
       | michaelbuckbee wrote:
       | I'm not a big fan of getting dental work done, much less "DIY
       | home dental" so was pretty skeptical of what they could possibly
       | be doing and was really pleasantly surprised by their tooth seal
       | instructions.
       | 
       | They're taking a somewhat well-known cavity prevention and enamel
       | remineralization treatment that has the unfortunate side effect
       | of turning your teeth black and replicating steps from a study to
       | avoid that.
       | 
       | One of several studies they link to:
       | https://www.scielo.br/j/bdj/a/rHSG9jRQDdY7sCFZzpNXYXy/?lang=...
        
       | robodale wrote:
       | My wife is a clinical pharmacist (rounds with medical doctors and
       | provides detailed patient analysis of their drug needs).
       | 
       | This article blew her mind.
        
         | oidar wrote:
         | In what way?
        
       | easyThrowaway wrote:
       | Never felt too much at ease with the DIY medicine arguments. I
       | mean, I agree _on principle_ with the idea of not being at the
       | whims of the pharmaceutical industry, but they always give me the
       | feeling of being just one step away from going fully  "Cancer/HIV
       | is caused by mobile phones and you can cure them with vitamin C"
       | and "Covid is a big pharma conspiracy" kinda people.
        
         | vitehozonage wrote:
         | I think it's very sad and a big problem that people like you
         | don't have the capacity/willingness to appreciate nuance
        
           | throwaway48476 wrote:
           | A lot of people with rare conditions are pretty much forced
           | to become experts on it to where they're reading the
           | literature and going to conferences. The medical community
           | isn't set up to help you if you have an uncommon issue and
           | aren't a relentless self advocate.
        
         | im3w1l wrote:
         | Some people could manage their health much better than the
         | current system. Other people would totally try to cure their
         | cancer with vitamin c.
         | 
         | A parallel that comes to mind is "accredited investors". These
         | are people that have chosen to opt out of the guardrails and
         | been allowed to by fulfilling certain criteria. Maybe something
         | like that would make sense for medicine.
        
           | lores wrote:
           | It's starting to be the case. Patients with terminal cancer
           | can opt into experimental treatments.
        
         | pstuart wrote:
         | Lots of existing medicine is a crap shoot -- look at the
         | possible side effects many of them have (including death).
         | 
         | I don't believe in the conspiracies you listed, but I
         | absolutely believe there are plenty of conspiracies in plain
         | sight (AMA restricting the number of doctors and fighting
         | against single payer, the FDA being in bed with big pharma,
         | etc).
         | 
         | We all should have the right to control our own bodies (which
         | extends to recreational chemicals). For those compounds that
         | are not yet vetted, we should have the right to make informed
         | choices.
        
         | samtho wrote:
         | I am not sure how you got to this slippery slope that doesn't
         | have a good reason to exist.
         | 
         | This movement is not about filling capsules with powdered
         | ginger to treat something that it's unable to. The goal is to
         | synthesize molecules that have been studied and that we know
         | work as a replacement for having to pay a doctor to get
         | permission to buy them.
        
           | knowitnone wrote:
           | If the problem is "having to pay a doctor to get permission
           | to buy them", we should fix that through policy. I agree with
           | you that this is a problem. Some things shouldn't require a
           | doctor's involvement like an ultrasound, even medication. If
           | I kill myself with taking a certain med (which many people
           | are intentionally doing with drugs already), that would be my
           | own fault.
        
       | ldjkfkdsjnv wrote:
       | Most medicine is complete bullshit, doctors have a specific set
       | of protocols they have to follow to avoid mal practice. There is
       | no nuance. Most pills will cause far more damage in long term
       | dependency and side effects than they will solve. ESPECIALLY for
       | psychiatric conditions.
       | 
       | Medicine mostly makes sense with broken bones and physical
       | surgeries.
       | 
       | Don't even get me started on dentistry.
       | 
       | For years, I struggled with severe dental issues, leading to
       | advanced gum disease. Dentists told me I'd eventually need tooth
       | extractions or major gum surgery. I've always hated going to the
       | dentist.
       | 
       | Two years ago, I decided to take control of my own dental care. I
       | bought a dental scaler kit online and started removing plaque
       | from the backs of my teeth. I learned the proper technique by
       | watching YouTube videos and now do this about once a week. The
       | results have been incredible--my teeth are spotless, I have no
       | gum bleeding, and I haven't had any cavities. I still go in once
       | a year for a professional cleaning of harder-to-reach areas like
       | my molars.
       | 
       | If you google whether you can do this, the internet is full of
       | large WARNING YOU CANNOT SCRAPE PLAQUE OFF YOUR TEETH. Every
       | single website is full of dentists screaming that you cant clean
       | your own mouth. This is clearly bullshit, you can actually just
       | scrape it off from the comfort of your own home. There's clearly
       | some risk, but if youre an intelligent adult, you can do it.
        
         | atentaten wrote:
         | Any particular kit and/or videos you recommend?
        
         | rqtwteye wrote:
         | I also have my doubts about dentist advice after seeing the
         | dramatically positive effects a waterpik and oil pulling had on
         | me and several other people I know. No gum problems, less
         | sensitive teeth. Due to several moves and my laziness I didnt
         | go to a dentist for cleaning for more than five years. Last
         | year I went again and had zero problems. Not even much plaque.
         | 
         | I wonder why dentists don't tell everybody to get a waterpik
         | first before any other treatments.
        
           | nicolas_t wrote:
           | I've actually had multiple dentists either telling me to get
           | a waterpik or praising me for having one. That was in China
           | (Japanese dentist though) and in France.
        
           | howard941 wrote:
           | A waterpik can push debris underneath your teeth. If you have
           | receding gums I'd be very careful about using one (again).
        
           | SoftTalker wrote:
           | My dentist recommends and supports using a Waterpik.
        
           | thebigspacefuck wrote:
           | Electric brush made a huge difference for me
        
         | tcdent wrote:
         | I do this, too. And since we practice it far more regularly
         | than a periodic visit to a specialist, we probably have cleaner
         | teeth than most.
        
         | giantg2 wrote:
         | "Most medicine is complete bullshit, doctors have a specific
         | set of protocols they have to follow to avoid mal practice."
         | 
         | I mostly agree with this. Most doctors are just reading off the
         | Epic professional version of WebMD for most
         | symptoms/conditions. It's especially important to do your own
         | research and be your own advocate for any serious conditions so
         | that you can ask the right questions, which sometimes snaps
         | them out of the scripted response and consider other
         | possibilities or concerns.
        
           | ldjkfkdsjnv wrote:
           | Its risky for them to say anything that falls outside the
           | guidelines. And they really dont have much to gain. They see
           | so many patients
        
       | ethanol-brain wrote:
       | It sounds interesting, but it really feels like they are
       | downplaying the risks here.
       | 
       | I'd be hesitant to put anything mixed in a DIY device with off
       | the shelf peristaltic pumps into my body without some additional
       | analysis.
       | 
       | If something like automated analysis was a possibility, then
       | maybe this would be more alluring.
        
         | XorNot wrote:
         | Yep: as someone with a chemistry background, synthesis is the
         | easy part.
         | 
         | Purification and analysis? That's the hard part.
         | 
         | Not getting screwed by additives, coatings or contamination?
         | Thats what the big bucks in lab gear cost (i.e. a metered
         | dispensing pump comes with a list of every element which
         | touches the dispensed fluid).
        
       | lubujackson wrote:
       | Just seeing this for the first time, and I love the hacker ethos
       | displayed here. Obviously there are Risks Involved especially for
       | health care, but I appreciate the well-researched and documented
       | reasoning behind their solutions. Let the people control their
       | own lives a bit more.
       | 
       | To me, the hacker mentality has, at its root, been about more
       | about shortcutting red tape and discarding the guardrails the
       | gov't put in place "for your own good". Often that comes hand in
       | hand with rule breaking and illegal actions.
       | 
       | But since healthcare has been so fully co-opted by moneyed
       | interests it is good to see things like this and "medical
       | vacations" grow in popularity - not because they are great
       | solutions but because they underline how thoroughly the current
       | system has screwed the pooch and will hopefully lead to real
       | change.
        
         | AlbertCory wrote:
         | I know someone whose wife was judged terminal, and he took her
         | to Mexico for some unapproved cancer therapies. This is not a
         | rich guy.
         | 
         | (She's dead now, as you might have guessed.)
        
           | petermcneeley wrote:
           | >judged terminal ... She's dead now
           | 
           | What is the intended message of this short story?
        
             | stavros wrote:
             | "Don't go to Mexico".
        
             | woleium wrote:
             | don't waste your last days with quacks
        
         | stavros wrote:
         | > more about shortcutting red tape and discarding the
         | guardrails the gov't put in place "for your own good".
         | 
         | Well, this really _is_ for the good of the vast majority of
         | people. The problem is that this also applies to a minority of
         | people, who have the skills to research thing and make educated
         | decisions about things.
         | 
         | It's not a bad general rule, but maybe it should be overridable
         | in certain circumstances, e.g. when you are experimenting on
         | yourself.
        
       | avgDev wrote:
       | There is a group that is producing medication that has yet to hit
       | the market for self use. Someone got a hold of a patent, found a
       | chemist and a lab willing to test the substance.
       | 
       | I'm waiting for the actual medication to hit the market but if
       | the FDA approval takes a long time, I will make the med myself.
       | The substance in the medication has been used orally for a long
       | time with a good safety profile and it was discovered that it can
       | help regenerate nerves.
       | 
       | Maybe I made all of this up to sound cool on the internet. If you
       | know what I mean.
        
         | QuantumGood wrote:
         | The FDA does not take information from other countries into
         | account much. EDIT: Foreign approval and use history can be
         | supportive information in an FDA review process, but are not
         | determinative factors for U.S. approval.
         | 
         | For example, Promethazine has been popular in the UK for a very
         | long time (ingredient in UK Sominex), but its not approved in
         | the U.S. as a sleep aid.
         | 
         | InHousePharmacy.vu/search.aspx?searchterm=promethazine
        
           | lenerdenator wrote:
           | Seems rather myopic to me.
           | 
           | We already share critical intelligence with the Five Eyes
           | countries; why not share medication safety/efficacy
           | information with them too?
        
             | NetworkPerson wrote:
             | Because then you can't sue someone as easily in the US when
             | you find out the drug popular in Europe actually caused
             | cancer 50 years later.
             | 
             | The US has to be sure it's completely safe. Or that it will
             | make enough money to outweigh the lawsuits later...
        
               | mnau wrote:
               | > The US has to be sure it's completely safe.
               | 
               | That doesn't make sense to me, who does US refer to in
               | this case?
               | 
               | The manufacturer is the one that would be sued and they
               | generally only want to expediate process.
               | 
               | FDA is one that aproves/denies application. They wouldn't
               | get sued for using data from other countries (or at least
               | no more that they already are).
        
               | lenerdenator wrote:
               | The "Five Eyes" countries are the United States, Canada,
               | the UK, New Zealand, and Australia.
               | 
               | Of the four countries that _aren 't_ the US, I'm sure
               | that all have regulatory safety standards that would
               | satisfy the safety and efficacy expectations of the
               | American public.
        
             | Beijinger wrote:
             | I remember a blog post of an MD or psychologist about
             | Russian/Soviet psychotropic drugs that are not used or
             | unknown in the west and used as an analogy that if Russia
             | had found new elements in the periodic table, and we would
             | not use them.
        
               | XorNot wrote:
               | It might be worth considering that until very recently,
               | Russia's military was _definitely_ supremely capable and
               | on-par with NATO.
               | 
               | Russia _lies_. About everything. And culturally Russians
               | have been immersed in a narrative that they 're the
               | absolute best in the world at everything, that all good
               | ideas were originally Russian ideas (see how the
               | narrative of LK-99 started getting modified before
               | anything was verified).
               | 
               | So do they have processes or techniques not used in the
               | West? Sure it's possible: but it's also far more likely
               | that the reason we don't use them is that the actual
               | investigation of their effectiveness can't reproduce the
               | results.
               | 
               | Because no one looks up the clinical studies: they just
               | repeat the fun narrative about big mysterious super-
               | technology from behind the Iron Curtain. Which itself was
               | essentially an invention of interest groups looking for
               | funding in the West (i.e. there's was never a "missile
               | gap" the US was going to lose).
               | 
               | Like as noted here: you remember the story, but not any
               | actual specific drugs or processes? Why?
        
               | Beijinger wrote:
               | EDIT: Someone found the link:
               | https://slatestarcodex.com/2014/08/16/an-iron-curtain-
               | has-de...
               | 
               | I did not find the blog post anymore. But the blog linked
               | to a pharmacy website that had tons of stuff available.
               | 
               | A few links:
               | 
               | https://en.wikipedia.org/wiki/Phenazepam
               | 
               | https://nah.sen.es/vmfiles/vol9/NAHV9N2202155_68EN.pdf
               | 
               | https://cosmicnootropic.com/blog/popular-nootropics/
               | 
               | https://medicine.umich.edu/dept/psychiatry/news/archive/2
               | 020...
        
               | Beijinger wrote:
               | "It might be worth considering that until very recently,
               | Russia's military was definitely supremely capable and
               | on-par with NATO."
               | 
               | I think Russia was not on-par with NATO after it
               | collapse, at least not in conventional warfare. They
               | missed the electronic revolution in warfare (See US-IRAQ
               | Gulf War I). But they are now back on par, possibly
               | better. Their jamming, air defense and rockets are top-
               | notch, possible better than NATOs. They can disrupt our
               | GPS System, we can't disrupt theirs since it is much
               | younger, speak better.
               | 
               | As a comparison: Germany had 3000 tanks during the cold
               | war. Now they have 300, 200 operational. Russia looses so
               | many tanks every month, and actually builds 100-200 new
               | ones every month. Germany had ammunition for two days of
               | warfare. After they gave some to Ukraine, they have
               | ammunition for one day left.
               | 
               | Russia has been underestimated. They are back and their
               | future looks pretty good, even with a dubious leader.
               | They won their war:
               | 
               | Defeat of the West? Emmanuel Todd and the Russo-Ukrainian
               | War https://www.thearticle.com/defeat-of-the-west-
               | emmanuel-todd-...
               | 
               | They have energy, they are not overpopulated, they have
               | fewer problems with immigration. In fact, they're even
               | looking for immigrants: https://movingtorussia.ru/ru
               | 
               | In the US I can smell the recession and banks will go
               | belly up very soon:
               | https://www.visualcapitalist.com/which-big-u-s-banks-
               | have-th...
               | 
               | In Germany too. Without Russian Energy their
               | manufacturing heavy country will deindustrialize.
               | 
               | At the same time, Russia is actively trying to replace
               | the US Dollar as the world reserve currency, together
               | with BRICS+. If successful, this will have a tremendous
               | impact on the US.
               | 
               | I am not a Putin troll, and I hope that I am wrong. But
               | the future has the nasty habit of taking unexpected
               | turns.
        
               | aguaviva wrote:
               | They have not "won the war". Not by any stretch. That's
               | just a pundit's plainly ideology-driven projection.
               | 
               | The fact that this author chose to call their book _The
               | Defeat of the West_ , and that its main thesis is that
               | this defeat is due to the "vaporisation of Protestantism"
               | should give one serious pause.
               | 
               | Perhaps not the best source to turn to for a serious,
               | impartial military analysis.
        
               | Beijinger wrote:
               | "Perhaps not the best source to turn to for a serious,
               | impartial military analysis."
               | 
               | Fair point. But it is from Emmanuel Todd. Who the f. is
               | Emmanuel Todd?
               | 
               | "Todd attracted attention in 1976 when, at age 25, he
               | predicted the fall of the Soviet Union, based on
               | indicators such as increasing infant mortality rates: La
               | chute finale: Essais sur la decomposition de la sphere
               | Sovietique (The Final Fall: An Essay on the Decomposition
               | of the Soviet Sphere)."
        
               | aguaviva wrote:
               | It doesn't matter who he is, or what he said when he was
               | 25. His perspective this time around is plainly warped,
               | and his analysis is just as plainly flawed, given the
               | current reality of what's happening on the ground in
               | Ukraine. You can tell that all by yourself, without
               | having to take some supposed visionary's word for it.
               | 
               | That's what happens when people get lucky early in their
               | careers. Sadly, it tends to go to their head.
               | 
               | See also:
               | https://en.wikipedia.org/wiki/Argument_from_authority
        
               | throwaway12287 wrote:
               | Link to blog post being described:
               | 
               | https://slatestarcodex.com/2014/08/16/an-iron-curtain-
               | has-de...
        
               | knowitnone wrote:
               | who cares what a blog post of an MD or psychologist says?
               | If a new element had use, of course we would use it. Are
               | you seriously telling me that if they discovered copper,
               | we won't use copper?
        
               | Beijinger wrote:
               | https://slatestarcodex.com/2014/08/16/an-iron-curtain-
               | has-de...
        
               | jhbadger wrote:
               | Weird analogy. The USSR/Russia _did_ discover new
               | elements, and while there was a certain amount of arguing
               | over names (as it wasn 't always clear who discovered
               | them first), there was no "not using" them because they
               | were Russian. That isn't how science works.
        
             | e-_pusher wrote:
             | There is the famous example of Thaladomide, which was
             | approved by the regulators in the Germany and caused a
             | disaster in birth defects:
             | 
             | https://en.wikipedia.org/wiki/Thalidomide_scandal
             | 
             | US FDA however was skeptical of the safety of the drug and
             | never approved it for sale in US.
        
           | slashdave wrote:
           | > The FDA does not take information from other countries into
           | account.
           | 
           | The FDA doesn't care where data comes from. Much of drug
           | testing in the US is done overseas in CROs.
           | 
           | > but its not approved in the U.S. as a sleep aid.
           | 
           | Approval is not automatic just because another country did
           | so. Someone needs to take responsibility and formally apply.
        
           | spondylosaurus wrote:
           | It's still prescribed in the US for other uses though. I
           | fucked up once and took one as an antiemetic, forgetting it
           | was a sedative... right before I had an important meeting.
           | Lesson learned :P
        
           | MassPikeMike wrote:
           | But for that kind of thing it would seem to be much easier
           | and probably cheaper just to mail order the drug from
           | overseas, or even book an inexpensive flight and buy some.
           | For example, bromhexine and ambroxol are cold remedies that
           | many people find effective, are not available in the US, but
           | are easy to mail order from any number of Japanese sellers.
           | The difficulty of hiring a lab or setting one up yourself
           | would seem to be worthwhile only for new or unusual medicines
           | that could not be obtained this way.
        
             | pennybanks wrote:
             | gettong those drugs are legal? and do you know someone in
             | japan willing to do this ? sounds pretty specific.
        
         | SuperShibe wrote:
         | Out of actual interest for my own medical use: Which medication
         | would this be about?
        
       | paulddraper wrote:
       | Fish antibiotics are amazingly cheap sources of an amoxicillin.
        
         | LinuxBender wrote:
         | Many stores are being forced to pull it for that reason. The
         | prepping community used to promote it and that caught the
         | attention of the wrong people. One alternative are a set of
         | doctors doing very low friction online consulting and
         | prescribing, some even selling kits with assorted antibiotics
         | but they are also getting pressured to stop.
        
       | sdwolfz wrote:
       | "From the moment I understood the weakness of my flesh, it
       | disgusted me. I craved the strength and certainty of steel. I
       | aspired to the purity of the Blessed Machine.
       | 
       | Your kind cling to your flesh, as if it will not decay and fail
       | you. One day the crude biomass that you call a temple will
       | wither, and you will beg my kind to save you. But I am already
       | saved, for the Machine is immortal..."
       | 
       | This is basically what was going through my mind while browsing
       | this website ;)
        
         | TZubiri wrote:
         | What is that, warhammer?
        
           | sdwolfz wrote:
           | Yes
           | 
           | https://youtu.be/9gIMZ0WyY88
        
       | lenerdenator wrote:
       | This just feels like drug dealing with a far more benevolent
       | motivation. I agree that it should ultimately be up to the person
       | but there's a lot of ways this could go wrong.
       | 
       | Remember, you're putting these substances in your body. Make
       | damned sure you trust the person you got them from. Like, "I
       | would trust you to raise my child in the event of my death"
       | levels of trust.
        
         | tcdent wrote:
         | > Make damned sure you trust the person you got them from.
         | Like, "I would trust you to raise my child in the event of my
         | death" levels of trust.
         | 
         | Do most people feel this way about formalized medical
         | practitioners today?
        
           | lenerdenator wrote:
           | In theory they go through a lot of training and regulation to
           | make sure that the goons stay out.
           | 
           | It's not 100% effective, but I do trust my PCP more than a
           | guy in Midtown selling PCP.
        
             | pcthrowaway wrote:
             | Well that's the point of DIY medicine, empowering people
             | like yourself to make your own PCP. Of course you trust it
             | more than the PCP from that guy in Midtown.
        
               | jzemeocala wrote:
               | I'm just waiting for the libertarian drug reform so that
               | I can get my PCP from my PCP
        
           | MSFT_Edging wrote:
           | If you're a woman in the US, doctors will sooner call your
           | issues anxiety and throw Xanax at you than to try to help you
           | figure out the causes. Sometimes they'll even get mad at you
           | if you don't want to take Xanax and suggest you're mentally
           | unfit.
        
             | silverquiet wrote:
             | I'm not a woman and it wasn't Xanax, but Ativan was a
             | miracle drug that cured many physical symptoms for me.
             | Doctors follow an algorithm where they look for common
             | stuff first ("when you hear hoof beats..."), and anxiety is
             | very common; I believe more so amongst women.
        
             | knowitnone wrote:
             | so you're saying men don't mistakenly diagnosed with
             | anxiety when it's not?
        
           | singleshot_ wrote:
           | I do, but I'm married to mine.
        
           | knowitnone wrote:
           | The alternative is to not visit a doctor of any sort. You
           | might take that further and not visit a mechanic. Medical
           | practitioners are not perfect. I trust they are doing their
           | job and they can get it wrong. Medicine is not easy. People
           | have to advocate for themselves if they don't think the
           | doctor got it right.
        
         | fph wrote:
         | Isn't the point of DIY medicine that _you_ are the person
         | making the drugs?
        
           | lenerdenator wrote:
           | Then make sure you trust the guy you got the instructions,
           | ingredients, and equipment from.
        
             | Ekaros wrote:
             | Considering the issues with snake oil. And well what
             | currently is marketed as magic cures for various things, I
             | rather not trust most instructions...
        
       | samtho wrote:
       | The strange responses in this thread has solidified my belief
       | that HN has strayed far from the "hacker ethos" that once
       | existed, with many people just able to parrot the "correct"
       | opinion de jour devoid of nuance.
       | 
       | Whether or not something like this is a good idea is neither here
       | nor there, rather the willingness to approach something with
       | skeptical curiosity has really been lost, and it is
       | disappointing.
        
         | grayhatter wrote:
         | I appreciate your putting my recent disgust into words. I
         | hadn't identified why it doesn't feel like hacker culture
         | anymore but that's matches my aversion. Too many comments want
         | to be right, and too few are trying to figure out how and why.
        
           | saxonww wrote:
           | I think there's a balance that some people don't appreciate.
           | Hacking your health has some additional risk vs. some
           | external system or process; your health is often
           | irreplaceable, and you might not get a second chance if you
           | screw it up. I think you should be a little more careful with
           | DIY pharma than you would other things. And I think you
           | should be very careful about evangelizing it to other people.
           | 
           | It is the case that some people get so wrapped up in
           | overcoming authority that it becomes the driving factor
           | behind what they support and what choices they make. It's
           | essentially the same thing you say you're disgusted with:
           | it's not about figuring out how and why, it's wanting to be
           | right and the authority to be wrong. The exact same behavior,
           | just from the other side of the fence. Call this a strawman
           | if you want, but I'm still asserting it's fact.
           | 
           | This is why I don't immediately see groups like four thieves
           | vinegar as positive. I don't know if the stuff they're doing
           | actually works or not. I suspect that you don't know this
           | either. It might work. They assert that it's simple and just
           | use their stuff and boom, daraprim (or whatever). But what
           | happens if it doesn't? The result is not a failure to adapt
           | some device to do something it wasn't intended to do, or get
           | data from a device the manufacturer would rather sell, it's
           | direct impact to your health.
           | 
           | Specific to their microlab, my immediate questions are around
           | sanitizing or disinfecting it. I have skimmed the
           | documentation and parts list. They recommend using 'water'.
           | There's no discussion about distilled vs. deionized vs. tap
           | water. There's nothing here about ensuring the mason jars and
           | tubing are clean to any particular standard. I haven't seen
           | any discussion yet about cleaning the reactor between
           | batches, in terms of ensuring there is no residue from the
           | prior batch. I sure hope I've just missed it, or this is
           | called out as a 'human tasks' in each recipe. Contamination
           | is ok (ish) with a Coca-Cola Freestyle machine at McDonald's.
           | You can tolerate your Coke tasting like 8 other drinks. I
           | don't think it's OK when making sofosbuvir.
           | 
           | I think you should be able to do just about whatever you want
           | to with your own body. Please be careful. But I don't think
           | you should be able to set yourself up as a counterculture
           | medical authority and not have people ask questions about it,
           | especially because a lot of people _won't_ ask questions.
        
         | lores wrote:
         | Many hackers are now old enough to have reflected on dystopian
         | science-fiction and come to the conclusion regulations are
         | useful, sometimes. And many hackers realise most people are
         | ignorant most of the time, us included, and do not trust
         | amateurs to have all of sufficient knowledge, thoroughness, and
         | benevolent intentions to manufacture powerful stuff you put
         | inside you. I don't think curiosity is discouraged, just the
         | impetus to turn it into action in this case.
        
           | nataliste wrote:
           | Are you British by chance?
        
         | pcthrowaway wrote:
         | I didn't necessarily get the same impression from the comment
         | thread that you did, given that there are a range of responses.
         | But I will say that the idea of intermingling the ethos of
         | Right to Repair with the ethos of Self-ownership[1] is one of
         | the most decidedly "hacker" novel ideas I've encountered on
         | Hacker News and I don't have words for the joy I experienced
         | browsing the submission.
         | 
         | [1] https://en.wikipedia.org/wiki/Self-ownership
        
         | knowitnone wrote:
         | Tell us what you think after you try out their dental cream and
         | DIY pharmaceuticals.
        
         | tptacek wrote:
         | It is probably impossible to write a good comment that has as
         | its thesis a characterization of the whole of HN as a
         | community.
         | 
         |  _Please don 't sneer, including at the rest of the community._
         | 
         | https://news.ycombinator.com/newsguidelines.html
        
       | nicolas_t wrote:
       | Ok, so I was interested in https://fourthievesvinegar.org/tooth-
       | seal/ Was happy that they say it's completely safe but... there's
       | no linked study that proves it's safe. On what basis is it safe?
       | 
       | There's been multiple recent studies linking higher fluoride
       | amount with reduced intelligence in children. How is that
       | different?
        
         | basch wrote:
         | I don't believe you are supposed to ingest the tooth sealant.
        
           | nicolas_t wrote:
           | Well yes and they do mention you shouldn't leak it but given
           | that it's on your teeth, how much leaches? Given that it
           | degrades over a year
        
             | literallycancer wrote:
             | The fluoride added to the drinking water in the US exposes
             | you to many more times than using a fluoride tooth paste,
             | so any leeching from this is likely inconsequential.
             | There's also papers linked in the website and it appears
             | that it's an improved version of the silver diamine
             | fluoride treatment, which a quick search reveals is FDA
             | approved.
        
         | grayhatter wrote:
         | it's different because the risk analysis for individual
         | decisions is completely disparate from the risk analysis of
         | policy decisions.
         | 
         | How is it connected?
         | 
         | Also I'd be interested in you're citation for the fluoride
         | assertion, the last I remember that was a conspiracy theory and
         | the actual published research was mixed and inconclusive?
        
           | nicolas_t wrote:
           | > it's different because the risk analysis for individual
           | decisions is completely disparate from the risk analysis of
           | policy decisions.
           | 
           | That's true, but when doing the risk analysis for individual
           | decisions, it helps to have actual data to make that
           | analysis. The website says it's safe without justification to
           | say why it's safe, how it's similar to known-safe mechanism,
           | etc.. "Trust me bro it's safe" is not exactly confidence
           | inducing.
           | 
           | > Also I'd be interested in you're citation for the fluoride
           | assertion, the last I remember that was a conspiracy theory
           | and the actual published research was mixed and inconclusive?
           | 
           | There's this recent report. This is for countries where
           | children received fluoride exposure amounts higher than 1.5
           | mg fluoride/L of drinking water which is higher than what
           | you'd get in the US.
           | 
           | https://ntp.niehs.nih.gov/whatwestudy/assessments/noncancer/.
           | ..
           | 
           | Most of the studies that show lower IQ are in Canada, China,
           | India, Iran, Pakistan, and Mexico where those levels can be
           | reached.
           | 
           | Example of studies:
           | 
           | - https://pubmed.ncbi.nlm.nih.gov/18695947/
           | 
           | - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923889/
           | 
           | - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409983/
        
       | thrance wrote:
       | This looks more like a libertarian nightmare than an anarchist
       | dream. I couldn't care less what you inject your body with, and
       | will always support open science, but this is no solution to the
       | USA's disastrous healthcare system.
       | 
       | The real "right to repair your body" necessarily involves a
       | socialized healthcare system, like in the rest of the West.
        
       | cdev_gl wrote:
       | As much as I'd love a long-term solution to dental cavities, I'm
       | leery of any treatment using silver nanoparticles, which can
       | cross the blood brain barrier and accumulate in the brain, where
       | they've been shown (in mice and in human models) to contribute to
       | neurodegenerative diseases.
       | 
       | I'm not a biologist or chemist, so I don't know enough to judge
       | if the method listed here is completely safe, but even a cursory
       | google shows cause to be concerned:
       | https://www.tandfonline.com/doi/full/10.1080/17435390.2018.1...
        
       | HybridCurve wrote:
       | While I can appreciate some of the intent to make certain
       | healthcare more accessible, it is never a good idea to have
       | anyone inexperienced attempt to perform some of the reactions
       | required to synthesize medicines. This should always be done by
       | experienced individuals with quality reagents and the proper lab
       | equipment. While it might be easy to substitute a mason jar for a
       | proper glass reaction vessel it is not so simple to find a
       | substitute for a gas chromatograph/mass spectrometer in the back
       | of your pantry.
       | 
       | IMO, The test equipment required to analyze the results of the
       | reactions is generally most cost prohibitive aspect of this type
       | of 'research'. And this is where I have a problem with these
       | guys: I don't see any plans available for building any of that.
       | Building many of these devices is not out of reach for a skilled
       | individual, and it makes more sense to me that this equipment
       | should more readily accessible than a glorified Keurig machine
       | for drugs. This kind of arrogance and lack of respect for the
       | discipline required in organic chemistry is going to result is
       | someone getting hurt.
        
       | knowitnone wrote:
       | We've always had the right to repair our body. We've just not
       | always had the tools. My personal view on this is rather to
       | opensource the tools like ultrasound, MRI, heart monitor, etc.
       | This would give the people the tools to help diagnose issues
       | without needing a doctor involved. It is taking a year just to
       | see a doctor.
        
       | ajb wrote:
       | Question from a non chemist: Ok so you do some chemistry and
       | produce a vial of supposed medicine, how do you tell that you
       | didn't fuck up and produce something toxic? I guess a modern lab
       | would just stick the result in a gas chromatograph or something
       | but you're not going to have one at home.
       | 
       | I vaguely recall (from, er, Sherlock Holmes) that old school
       | analytic chemistry could figure out what an unknown chemical with
       | cheap reactions and tests, but does anyone even know how to do
       | that any more? Is it automatable?
        
       ___________________________________________________________________
       (page generated 2024-09-07 23:00 UTC)