[HN Gopher] Brain Scientists Discover the Glue That Makes Memori...
       ___________________________________________________________________
        
       Brain Scientists Discover the Glue That Makes Memories Stick for a
       Lifetime
        
       Author : kungfudoi
       Score  : 46 points
       Date   : 2024-09-01 18:59 UTC (4 hours ago)
        
 (HTM) web link (www.scientificamerican.com)
 (TXT) w3m dump (www.scientificamerican.com)
        
       | ImPostingOnHN wrote:
       | Not that Scientific American doesn't deserve to be funded, but
       | I'm not sure how I feel about this article being paywalled while
       | the scientific paper it's summarizing is free:
       | 
       | https://www.science.org/doi/10.1126/sciadv.adl0030
        
       | PcChip wrote:
       | Why are there so many paywalled links lately?
        
         | fnordpiglet wrote:
         | Advertising based funding was always a scam and doomed to be a
         | race to the bottom as per unit margins can barely support unit
         | costs of production. The incentives for attention capture and
         | sale of private information are the only material market
         | pressure.
         | 
         | Sadly in a world of scarcity journalists need to eat too, have
         | families, retirement funds to accumulate, etc. Quality of work
         | requires paying humans, which requires funds from the consumers
         | of the product one way or another. By paying as a first order
         | user you boost the unit margin considerably and change the
         | incentive structure to prioritize your priorities, not the
         | priorities of advertisers and surveillance economy
         | participants.
         | 
         | Sadly I don't think anyone has come up with an alternative way
         | of paying for the people to do the work.
        
           | sgc wrote:
           | Here is a (not very novel) idea: Netflix for news. I would
           | happily pay for a solid aggregator subscription. But the
           | number of times that some random news site from halfway
           | across the world is the site of the day just keeps me away
           | from news subscriptions. It feels like I am pigeon-holing
           | myself and limiting my worldview to that of a couple of
           | editorial boards / companies.
           | 
           | Also, for sites that want to have single-site subscriptions:
           | If you bundle with print, give me the option of donating my
           | print subscription to a library if I don't want the hard
           | copy. Many people for whom the subscription is too much
           | friction / not a great value proposition, will bite if at
           | least they know the libraries are eating for free.
        
             | ASalazarMX wrote:
             | Just imagine this 2034, and the NewStream service is
             | competing with a bunch of newspapers selling their own news
             | streams. The original NewStream is hiring reporters to make
             | its own news, and some people like them.
        
             | bn-l wrote:
             | This is what I want also (it's strange it doesn't exist
             | yet). I'm not going to pay a subscription to a hundred
             | different news sites.
        
             | crooked-v wrote:
             | Apple News+ is the shitty cable network version of this,
             | where you pay for access but you still get the ads anyway.
        
         | bookofjoe wrote:
         | https://archive.ph/MSetk
        
       | bookofjoe wrote:
       | Dupe: https://news.ycombinator.com/item?id=41385322
        
         | metadat wrote:
         | No discussion == no dupe.
         | 
         | (Unfortunate sometimes. You are absolutely one of the most
         | prolific HN submitters, Joe!)
        
           | bookofjoe wrote:
           | "No discussion == no dupe." Excellent point, taken!
        
           | bookofjoe wrote:
           | "You are absolutely one of the most prolific HN submitters,
           | Joe!"
           | 
           | It took me until I reached 76 years of age to finally
           | discover what I'm good at.
        
       | pfdietz wrote:
       | This is mildly terrifying. Imagine a drug that penetrates the
       | blood-brain barrier and inhibits the interaction of these two
       | proteins. Administered over a long enough period of time, could
       | it erase your memories... effectively, erasing you? Imagine such
       | a thing being used maliciously, by governments against their
       | critics, or as a covert weapon.
        
         | PaulKeeble wrote:
         | My first thought is someone is going to do these experiments,
         | probably on a prisoner. Then my second thought was death row
         | prisoners being given the choice of a memory wipe or death as
         | some sort of attempt at rehabilitation. I can't yet see half
         | the ways this could go horribly for humanity.
         | 
         | On the other hand knowing how this works we might be able to
         | boost the process and make people super fast learners, that
         | could be really cool.
        
           | crooked-v wrote:
           | That kind of thing is what gets you a society with incentives
           | to produce more death-row convictions.
        
           | akira2501 wrote:
           | > My first thought is someone is going to do these
           | experiments, probably on a prisoner.
           | 
           | In the animal model, they surgically altered the animals to
           | have an injection cannula placed in their skulls, it's
           | obviously hard to target, so you just install it and run the
           | experiment, then after the experiment, you kill and necropsy
           | the animal to see if it was in the right place after all. If
           | it was you can keep those results, if it wasn't, you throw
           | those results away.
           | 
           | Meanwhile the test is putting them on a rotating platform and
           | shocking their feet on certain platform areas. Then waiting
           | for them to avoid it habitually. Then you inject them. Then
           | you see if they still avoid it.
           | 
           | These guys basically know next to nothing about how memories
           | are formed at this point. Their test is so amazingly cruel
           | while being particularly narrow that you can't actually
           | divine anything useful from it. Except maybe more funding to
           | keep shooting in the dark at these animals expense.
        
         | mewpmewp2 wrote:
         | Yes, although, you could just poison and kill anyone as easily
         | already now, so I'm not sure if it's exactly more terrifying or
         | not.
        
           | grugagag wrote:
           | Possibly more humiliating to see an opponent mind be
           | completely wiped out, possibly living the rest of their lives
           | as a vegetable and to need the care of someone. When one is
           | killed for their ideas they become a martyr of sorts.
        
             | smith7018 wrote:
             | It is already much easier to turn someone into a vegetable
             | or to mentally incapacitate people
        
             | mewpmewp2 wrote:
             | I think if you want terrifying, look for the "Devil's
             | Breath" or Scopolamine. This has been actively used by
             | robbers and can ruin a life forever.
        
         | wtetzner wrote:
         | I wonder if there's something in our food and/or environment
         | that effectively does that over long periods of time,
         | ultimately causing some forms of dementia?
        
         | throw7 wrote:
         | MKUltra v2.0
        
         | dv_dt wrote:
         | On the other hand something like that might also have
         | legitimate medical uses with ptsd treatments.
        
         | mdhb wrote:
         | Of course the most deranged and paranoid government is out to
         | get me comment got voted to the top of HN of an unrelated
         | article.
        
       ___________________________________________________________________
       (page generated 2024-09-01 23:00 UTC)