[HN Gopher] Neurotechnology numbers worth knowing (2022)
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       Neurotechnology numbers worth knowing (2022)
        
       Author : Jun8
       Score  : 141 points
       Date   : 2024-08-25 03:40 UTC (19 hours ago)
        
 (HTM) web link (milan.cvitkovic.net)
 (TXT) w3m dump (milan.cvitkovic.net)
        
       | danwills wrote:
       | I don't know why but I just love being able to read all of this
       | fascinating information in such a compact form, just amazing!
       | Heading back over to read the rest now!
        
         | DaiPlusPlus wrote:
         | > fascinating information
         | 
         | ...you don't find it uncomfortable or distressing to be
         | confronted with the dry facts and hard-limits of the 1.5Kg
         | squishy-pink prison we're all trapped-inside and all condemned
         | to die inside?
        
           | Terr_ wrote:
           | > "Not at all," said the medtech. "Think of all the work he
           | represents on somebody's part. Nine months of pregnancy,
           | childbirth, two years of diapering, and that's just the
           | beginning. Tens of thousands of meals, thousands of bedtime
           | stories, years of school. Dozens of teachers. And all that
           | military training, too. A lot of people went into making
           | him." She smoothed a strand of the corpse's hair into place.
           | "That head held the universe, once."
           | 
           | -- _Aftermaths_ by Lois McMaster Bujold
        
           | danwills wrote:
           | Quite the opposite for me it kinda just makes it seem even
           | more amazing that it exists and works at all and how much
           | humans have worked out about it!
           | 
           | There's some interesting regenerative medicine avenues
           | (Michael Levin's stuff, planarian worms don't die from old
           | age) that I have some hope might eventually slightly reduce
           | the 'condemned to die' side of the picture for humans also.
        
           | gary_0 wrote:
           | It's so delicate, too. Drop the squishy pink thing and its
           | ancillary support-meat on a random part of Earth and most
           | likely it drowns in an ocean, freezes on a mountainside,
           | dries out in a desert, or starves in a wasteland.
           | 
           | That's leaving aside the other 99.99999999% of the universe
           | where it chokes on vacuum or is blasted by radiation.
           | 
           | And even in a perfect habitat with an ideal genotype and
           | phenotype, its functional lifetime is a mere century
           | bookended by billions of years of nonexistence.
           | 
           | So yeah.
           | 
           | I try not to think about all that.
        
             | protomolecule wrote:
             | >the other 99.99999999% of the universe
             | 
             | You are off by so many orders of magnitude.
        
           | cen4 wrote:
           | And many of those numbers aren't static. They change.
           | 
           | The Theory of Bounded Rationality emerged as a reaction to
           | growing awareness within the chimp troupe, of the numerous
           | limitations of that chimp brain. Its a useful tool when
           | coping with complex ever changing reality.
        
           | layer8 wrote:
           | How does it make any difference about being trapped and
           | dying?
        
           | dennis_jeeves2 wrote:
           | >...you don't find it uncomfortable or
           | 
           | Well, you have heard it: Ignorance is bliss. That's how the
           | masses survive.
        
       | agumonkey wrote:
       | In case someone is as confused as I was, a french is a gauge unit
       | https://en.wikipedia.org/wiki/French_catheter_scale
       | 
       | It's also a good joke opportunity, but for the link above it's
       | not a joke.
        
       | dominicq wrote:
       | This is awesome. Even though many think it unpopular, I've always
       | found that a certain measure of rote learning is beneficial, if
       | not straight up necessary.
       | 
       | > Having them memorized and at your fingertips is great for
       | sanity checking ideas.
       | 
       | This is essentially the reason. There are certain idea pathways
       | you simply cannot traverse if you constantly need to check
       | specific values. And I think that it might be possible that your
       | subconscious simply won't "give" you an idea until you have
       | specific facts memorized.
       | 
       | Just think how much more difficult your life would be if you had
       | no concept of a kilometer/mile, and constantly needed to do the
       | math to check how far something is in... meters/yards, or
       | something.
        
         | HPsquared wrote:
         | It's like knowing how much clock speed, RAM and storage is on a
         | typical computer.
        
         | epgui wrote:
         | Yep. 12 years studying biochem and health science makes that
         | very clear.
         | 
         | Knowing and understanding are intimately tied, and it's
         | questionable whether one can meaningfully understand anything
         | without first knowing things.
        
       | fredgrott wrote:
       | hmm, you know there is this big book of all chemicals....no one
       | in the science communities with any professional sense and skills
       | recommends rote remember such lists....
       | 
       | For example, is it better to remember by rote all the amino acids
       | or is it better to reason which is which be the quantum mechanics
       | involved in the different bonding groups?
       | 
       | Most in biochemistry go with the 2nd option....and succeed.
        
       | egnehots wrote:
       | I would be interested in a computer science only version.
       | 
       | A quick search didn't bring up an already existing one :(
        
         | Sajarin wrote:
         | Isn't the computer science version Peter Novig's, "Latency
         | Numbers Every Programmer Should Know" table?
         | 
         | https://norvig.com/21-days.html#answers
         | 
         | Edit: This version is also quite nice -
         | https://gist.github.com/hellerbarde/2843375
        
         | teraflop wrote:
         | One classic set of numbers is Jeff Dean's "latency numbers
         | every programmer should know", as quoted in a bunch of places
         | including: https://highscalability.com/google-pro-tip-use-back-
         | of-the-e...
         | 
         | (EDIT: apparently Dean got this table from Peter Norvig as
         | another commenter mentioned.)
         | 
         | The disk numbers are a bit outdated now because of the
         | overwhelming shift from spinning hard disks to SSDs, but most
         | of the others have held up surprisingly well AFAIK. For
         | instance, neither CPU L1 caches nor the speed of light have
         | gotten dramatically faster in the last couple decades.
        
         | shepherdjerred wrote:
         | https://github.com/sirupsen/napkin-math
        
       | dragon96 wrote:
       | Next up: Numbers every math person should know
        
       | tsurba wrote:
       | >Tennis court size is in feet
       | 
       | Lol.
        
       | p0nce wrote:
       | I found this book very helpful to understand most cellular
       | process, and viruses, with an intuition of how things works at
       | these scales: https://www.amazon.com/Machinery-Life-David-S-
       | Goodsell/dp/03...
        
       | m3kw9 wrote:
       | I'm not getting why these are significant because it's spelling
       | out what it seems the tip of the ice berg numbers, and there are
       | a lot more missing, and even if you spell them all out, it's too
       | general to be useful. However it is interesting
        
       | mrgoldenbrown wrote:
       | Suggestions from someone who hasn't used sub mm units in decades
       | and is therefore out of practice: since the first section is
       | supposed to orient us, remove the French =3mm bullet point, you
       | never mention French again as far as I can see, so it's just
       | trivia. Instead, try to link the first 2 points - maybe express
       | human hair in nm instead of um, so that we can then visualize an
       | angstrom (something most people don't know about) in terms of
       | human hair (something most folks do know). Don't make us convert
       | nm and um our heads.
        
       | pazimzadeh wrote:
       | > A cage of 5 mice costs ~$1k upfront and ~$5k/yr recurring You
       | can get mice a lot cheaper than that, I'm not sure what kind of
       | mice he's referring to but the prices depend on the vendor and
       | mouse type.
       | 
       | Where I work it's about $2 a day to house a cage of 5 mice. It's
       | about $30 a mouse if you get C57BL/6NJ's from Jackson:
       | https://www.jax.org/strain/005304
       | 
       | So more like $150 for 5 mice and $800 to house for a year.
       | 
       | Another good one to know if the size of antibodies (10-12 nm).
        
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       (page generated 2024-08-25 23:01 UTC)