[HN Gopher] Can you inherit memories from your ancestors?
       ___________________________________________________________________
        
       Can you inherit memories from your ancestors?
        
       Author : giuliomagnifico
       Score  : 113 points
       Date   : 2024-06-17 12:47 UTC (1 days ago)
        
 (HTM) web link (www.theguardian.com)
 (TXT) w3m dump (www.theguardian.com)
        
       | ch4s3 wrote:
       | This is such an odd preoccupation of places like the guardian and
       | has a lot of the hallmarks of the discredited recovered memory
       | movement/therapy[1][2]. There's never any discussion of epigentic
       | changes that effect somatic cells vs gametes, or even of the
       | competing definitions of epigenetic changes.
       | 
       | Here's a quote from the article:
       | 
       | > Scientists working in the emerging field of epigenetics have
       | discovered the mechanism that allows lived experience and
       | acquired knowledge to be passed on within one generation
       | 
       | This is obviously such a nonsense interpretation of epigenetic
       | changes that it's hard to take anything in the article seriously.
       | 
       | Obviously there's real science happening around epigenetics and
       | there are interesting findings, reporting like this is a really
       | big leap.
       | 
       | [1] https://en.wikipedia.org/wiki/Recovered-memory_therapy
       | 
       | [2] https://www.nytimes.com/2022/09/27/opinion/recovered-
       | memory-...
        
         | moralestapia wrote:
         | >This is obviously such a nonsense interpretation of epigenetic
         | changes that it's hard to take anything in the article
         | seriously.
         | 
         | No one (including you) really knows the whole extent of
         | epigenetic effects, so I would suggest you give it another
         | read.
         | 
         | We are still at (estimate) 10% known / 90% unknown in Biology.
         | Source: Biologist for 20 years now.
        
           | ch4s3 wrote:
           | I read the article, the linked study, and two studies citing
           | the linked study. The claim that memories or "lived
           | experience" is inherited is not supported by the study.
        
           | BenFranklin100 wrote:
           | Erm...memories -- by any biologically reasonable definition--
           | are separate from epigenetic changes. No serious researcher
           | would conflate the two, other than perhaps hippy-dippy
           | 'biologists' who struggled through 'Physics for Poets', as
           | undergrads. Source: Biophysicist for 30 years now.
        
             | moralestapia wrote:
             | And yet ...
             | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248710/
             | 
             | Btw, read the site guidelines. This is a place for
             | discourse, not berating others.
        
               | ch4s3 wrote:
               | Follow up work has not held up the 2008 article you
               | shared[1], and has in fact shown that larvae do not carry
               | over memories through metamorphosis.
               | 
               | [1] https://www.quantamagazine.org/insect-brains-melt-
               | and-rewire....
        
               | BenFranklin100 wrote:
               | Further, even if the study had held up, there is a vast
               | difference between memories retained through an
               | individual metamorphosis event, and passing memories
               | along to offspring resulting from sexual reproduction.
               | The OP fails to recognize this obvious point.
        
               | ch4s3 wrote:
               | Yes, I completely agree.
        
               | moralestapia wrote:
               | >The OP fails to recognize this obvious point.
               | 
               | I don't. You're attacking a straw man.
               | 
               | You wrote,
               | 
               | >Erm...memories -- by any biologically reasonable
               | definition-- are separate from epigenetic changes.
               | 
               | I replied with a study showing the opposite to be true.
        
               | BenFranklin100 wrote:
               | No, I said, "There is a vast difference between memories
               | retained through an individual metamorphosis event, and
               | passing memories along to offspring resulting from sexual
               | reproduction. The OP fails to recognize this obvious
               | point."
               | 
               | You're selectively quoting and then re-arranging the
               | quotes to attempt to make yourself look better.
               | 
               | Honestly, for someone to be posting this nonsense with a
               | link to their LinkedIn professional profile in their bio
               | is kind of career suicide. You've inadvertently stumbled
               | into an argument on a IT tech website with people who are
               | bona fide life scientists and are embarrassed and are
               | clumsily trying to save face.
        
               | moralestapia wrote:
               | My career is doing just fine, actually. Like, better than
               | ever and I'm not making this up.
               | 
               | Feel free to add me on LinkedIn, I have no issue in
               | people knowing who I am; should I be scared or anything?
               | Lol. You should try not being anonymous, just a
               | suggestion, :).
               | 
               | You said:
               | 
               | "Memory [...] is separate from epigenetic changes"
               | 
               | I replied with a study that seems to suggest otherwise.
               | That's not really hard to follow ...
               | 
               | >IT tech website
               | 
               | Hmm naw man, Hacker News is _way_ more than that. Also,
               | why would I be embarrassed? You are just projecting too
               | much unto others, chill.
        
               | moralestapia wrote:
               | >and has in fact shown that larvae do not carry over
               | memories through metamorphosis
               | 
               | Nope.
               | 
               | The 2008 study is _" the first to demonstrate
               | conclusively that associative memory survives
               | metamorphosis in Lepidoptera"_.
               | 
               | The article you cited does not disprove this, but rather
               | it shows the brain structure of (some, at least) insects
               | get completely re-arranged before/after their transition
               | to adulthood.
               | 
               | For me, this only makes the 2008 study _more_
               | interesting, since the memories could still persist, even
               | after a completely new brain architecture (!).
        
               | ch4s3 wrote:
               | That 2008 study has never been reproduced and the piece
               | in Quanta points towards it being impossible. Our current
               | understanding of memory is that it has a physical basis,
               | so that 2008 study is likely wrong.
        
               | moralestapia wrote:
               | Appealing to authority is one of the most primitive
               | logical fallacies out there.
               | 
               | But if we're going to do that, let's do it properly and
               | choose the peer reviewed article written by experts in
               | the field over a blog post written by a "science
               | communicator".
               | 
               | -\\_(tsu)_/-
        
               | BenFranklin100 wrote:
               | Ha. You tried to appeal to authority by insinuating
               | you're a professional biologist. First, you're not. You
               | appear to be primarily an app developer, not a
               | researcher. Which is why I mocked you by pulling my 30
               | years on you.
        
               | moralestapia wrote:
               | I definitely would not call myself a "professional
               | biologist" as that would make a whole room burst with
               | laughs, lol. So, you're right on that.
               | 
               | But I do work as a researcher, publish some interesting
               | papers from time to time and, yes, I think I'm also an
               | "app developer", in the sense that I've made some apps?
               | 
               | These kind of arguments you make really come across as
               | quite infantile, to be honest. I'm going to have to stop
               | engaging with you because no substantial value is added
               | to the conversation while you already crossed the line to
               | personal attacks, several times, even after you've been
               | told about it and pointed to this site's rules. Find
               | somebody else to engage with your tantrums, I'm out.
        
               | BenFranklin100 wrote:
               | You serve up a distasteful dish of arrogance and
               | ignorance. You drop into a conversation implying you're a
               | professional biologist ("Source: biologist for 20 year")
               | when you're not - that's the arrogance. You then make
               | wildly inaccurate statements any real life scientist
               | knows isn't true for cheap internet points from software
               | folks who don't know any better- that's the ignorance.
               | You finish it off with a dollop of childishness on top by
               | complaining when actual scientists call you out on your
               | nonsense. Do better. I know you can.
        
               | ch4s3 wrote:
               | Again the 2008 study has never been reproduced to my
               | knowledge and defies everything we know about how memory
               | is stored, so I think skepticism of such an incredible
               | claim is warranted.
        
               | BenFranklin100 wrote:
               | I'm not berating you. I'm ridiculing you. Anyone with an
               | actual 20 years experience as a biologist would not be
               | making such outlandish statements. From your profile, you
               | seem like more of an app developer than a genuine
               | biologist anyway.
        
               | moralestapia wrote:
               | This is definitely over the line.
               | 
               | cc @dang?
        
         | giantg2 wrote:
         | Eh, I mean what other explaination is there for "instinct". You
         | have genetic and epigenetic factors that give something a
         | predisposition to respond to stimuli in a specific way. Makes
         | sense to me, but it's just a theory (as most things are) and we
         | have a lot more to learn.
        
           | ch4s3 wrote:
           | There's a big difference between DNA methylation on gametes
           | leading to behavioral predispositions in offspring and the
           | claim that memories and experiences are inherited.
        
             | giantg2 wrote:
             | It depends on what you mean by memories. I'm not a fan of
             | the Guardian as I've seen stuff editorialized to the point
             | it conveys misinformation. This article is poorly written
             | to the point the writer doesn't seem to understand the
             | topic.
             | 
             | "Epigenetic memories" is different than colloquial
             | "memories". The article seems to completely miss this. And
             | of course people who haven't been exposed to that domain
             | specific concept are likely to misinterpret it.
        
               | everdrive wrote:
               | It's intentionally misleading given that "memory" has a
               | common understanding. If they simply wanted to keep the
               | article approachable, they could even just simply write
               | "they're analogous to memories, but don't work like
               | memory as most people understand it."
        
               | ch4s3 wrote:
               | Memory is the wrong word to use even like that. To the
               | extent that there is DNA methylation in gametes, it will
               | up or down regulate the expression of existing genes in
               | the DNA. Nothing is created de-novo as in memory, you
               | can't look at the resultant gene regulation and look
               | backwards to a cause.
        
               | giantg2 wrote:
               | Then please go tell all the publications and researcher
               | that they are wrong for using the term "Epigenetic
               | memory" in thier domain. Or are you a domain expert (in
               | the minority if you are)?
        
               | ch4s3 wrote:
               | The study[1] mentioned in the guardian does not contain
               | the phrase "epigenetic memory", and only contains the
               | word memory twice, and both uses are of the conventional
               | definition. The author in the guardian is misrepresenting
               | the science.
               | 
               | [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923835/
        
               | giantg2 wrote:
               | I agree that the article is garage. The point of
               | contention is around epigenetic memory being a thing or
               | not. It is a common term used in the domain, such as in
               | this paper and others.
               | 
               | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225062/
        
               | ch4s3 wrote:
               | You could probably replace the word memory in that paper
               | with maguffin and not change the meaning. It's totally
               | unconnected to the common definition or the use in
               | neurology. I guess what I'm getting at is that this kind
               | of reporting obscures what's going on intentionally for
               | the political aims of the guardian. Which I think is
               | lousy.
        
               | giantg2 wrote:
               | Yes, and that's true of computer "memory" as well.
        
               | moralestapia wrote:
               | >what's going on intentionally for the political aims of
               | the guardian
               | 
               | Ok, now this is something!
               | 
               | So, please enlighten me, what could be the political
               | agenda being pushed by an article pondering around
               | whether memories can be inherited or not?
        
               | ch4s3 wrote:
               | Vague notions of "inherited trauma" are a regular hobby
               | horse of people in the broader political sphere of the
               | guardian at the moment.
        
               | biotinker wrote:
               | I'm not a domain expert in epigenetics, but in grad
               | school for bioinformatics I did a bunch of research on
               | nucleosome positioning[0] which is epigenetics-adjacent.
               | 
               | "Epigenetic memory" is the term of art I was taught in
               | grad school. Either they've changed that in the last 10
               | years, or ch4s3 is attempting to assert a different
               | definition of "memory" than the one used in the field.
               | 
               | They are also incorrect. DNA methylation is an actual
               | methyl group chemically binding to an actual DNA
               | nucleotide, and staying there. When we flip a bit on a
               | hard drive platter we call that "memory" as well.
               | 
               | [0] https://scholar.google.com/citations?user=MJO2lYIAAAA
               | J&hl=en
        
           | squidbeak wrote:
           | Instinct is totally different from memory.
        
             | ch4s3 wrote:
             | That's precisely the problem outside of the lack of any
             | direct evidence of the underlying mechanism.
        
             | conradolandia wrote:
             | How do you know?
        
             | giantg2 wrote:
             | Which "memory" are you talking about? "Epigenetic memory"
             | is different, and it's related to, and influences,
             | instinct.
        
           | HarHarVeryFunny wrote:
           | Well, you've got brain wiring that causes you to respond to
           | stimuli in a certain way. A small portion of that wiring is
           | genetic (e.g. opposite sex attraction, fear of heights,
           | disgust at certain smells), and the rest comes from prior
           | sensory exposure (i.e. is learnt during your own lifetime).
        
         | everdrive wrote:
         | Is there a good, real-world example of how we think epigenetics
         | works? I've seen a lot of mentions that "epigenetics _proves_
         | that intergenerational trauma is real!" -- and at least to my
         | eyes this feels like a stretch of the science. For instance,
         | why are epigenetic effects inherited? Why is it not the case
         | that in environment, the parents experience one environment and
         | so some genes are expressed. (ie, epigenetics happens based on
         | that environment) and then the children are in the a different
         | environment, and so different genes are expressed.
         | 
         | Do I have a wholly-incorrect understanding of epigenetics? Is
         | there a clear and simple example of an epigenetic mechanism?
        
           | gmm1990 wrote:
           | just look up dna methylation
        
             | everdrive wrote:
             | Thank you, I will do so.
        
           | ch4s3 wrote:
           | It seems pretty clear for example that being an alcoholic can
           | cause DNA methylation in your gametes such that your
           | offspring have a higher risk above and beyond regular genetic
           | factors to become an alcoholic. However that is at a
           | population level and there are complicating factors.
           | 
           | Inherited trauma is totally unsupported but up or down
           | regulated gene expression based on environmental factors
           | before your conception are supported by some compelling
           | evidence.
        
             | jvanderbot wrote:
             | I'm trying on a mental model re: Epigenetics. How does this
             | look:
             | 
             | Your genes are a recipe book, not a blueprint. What recipe
             | is chosen is based somewhat on environmental effects. When
             | you reproduce, you shuffle together the parents book + the
             | earmarks on the pages.
        
               | ch4s3 wrote:
               | I'm not sure if that totally fits. There's a kind of
               | signal amplification or de-amplification happening.
        
               | jvanderbot wrote:
               | Yeah I was using dogear as a way of signalling "prefer
               | this page"
        
               | ch4s3 wrote:
               | Yeah, I assumed that, but down regulating isn't well
               | captured in that metaphor.
        
             | margalabargala wrote:
             | > Inherited trauma is totally unsupported
             | 
             | This is only true if you take a pretty narrow definition of
             | the word "trauma".
             | 
             | One example would be an ancestor experiencing famine, who
             | then passes down epigenetic markers have marked effects on
             | their offspring in terms of health, longevity, and
             | behavior.
             | 
             | Here's a Nature article on it:
             | https://www.nature.com/articles/s41418-023-01159-4
             | 
             | > "Collectively, these discoveries infer the existence of
             | "a heritable memory of starvation/hunger"."
        
               | ch4s3 wrote:
               | The Dutch Hunger cohort study is highly suspect. However,
               | the idea that someone is literally starving to death just
               | before or during gestation having some knock on genetic
               | effects is not all that surprising. But again, the phrase
               | "inherited trauma", as it's typically used is bunk.
               | 
               | Also the phrase "a heritable memory" is kind of nonsense
               | even with respect to epigenetic changes. Again what we're
               | talking about with epigenetics is up or down regulation
               | of your existing genes, not some new information being
               | encoded.
        
               | margalabargala wrote:
               | I found the research about the Chinese Suihua cohort to
               | be more compelling.
               | 
               | I fully agree that someone starving to death right around
               | the time of pregnancy could have some knock on effects;
               | this is discussing changes in the _following_ generation,
               | the ones that are tens of years removed from the
               | starvation event.
               | 
               | > Also the phrase "a heritable memory" is kind of
               | nonsense even with respect to epigenetic changes. Again
               | what we're talking about with epigenetics is up or down
               | regulation of your existing genes, not some new
               | information being encoded.
               | 
               | I wonder if you are missing the forest for the trees here
               | somewhat. We're talking about the up/down regulation of
               | specific genes based on specific methylation patterns in
               | DNA that are present only because of some event that
               | occurred. It's not memory in the sense of "I remember
               | what I had for breakfast this morning", but it's memory
               | in the sense of "these methylation patterns exist because
               | their genesis was triggered by a specific event in the
               | last few generations". That _IS_ new information being
               | encoded, just in a more fuzzy way than with neurons or
               | computer memory.
               | 
               | I would need more convincing to think the phrases you
               | mention are nonsense/bunk. Could you perhaps articulate
               | the definitions you're using for "trauma" and "memory"? I
               | think we are using different definitions, as it seems
               | clear what is meant by the phrases as used.
               | 
               | EDIT: what issue do you take with the Dutch hunger study?
               | I hadn't heard criticism about it before, and I just
               | googled "dutch hunger cohort study criticism" and found
               | nothing.
        
               | moralestapia wrote:
               | >just googled "dutch hunger cohort study criticism" and
               | found nothing
               | 
               | x2
               | 
               | @ch4s3 is making some pretty strong claims here and
               | there, for which I do not see the evidence either.
               | 
               | Don't take me wrong, I don't mean to suggest he's just
               | being a quack; but rather, this is an invitation for him
               | to substantiate his knowledge. The more we learn the
               | better, :).
        
               | ch4s3 wrote:
               | So check this study out[1] it uses the Dutch hunger
               | winter families cohort day as a starting point, but uses
               | a web based form to follow up on obesity. This is
               | obviously not going to yield great results. And the
               | findings show that only the adult children of famine
               | exposed fathers are more likely to be obese which seems a
               | little add. It has nearly 600 citations.
               | 
               | My criticism is that a lot of studies based on the data
               | to lazy things like this, draw big conclusions, and get a
               | lot of citations but there just isn't much to them.
               | 
               | [1] https://scholar.google.com/scholar?hl=en&as_sdt=0%2C3
               | 9&q=%E2...
               | 
               | Wooos, posted the wrong link earlier. https://obgyn.onlin
               | elibrary.wiley.com/doi/abs/10.1111/1471-0...
        
               | moralestapia wrote:
               | The link you posted is a list of "About 1,870 results".
               | 
               | I really don't have the time or energy to go through all
               | of them, tbh.
               | 
               | -\\_(tsu)_/-
        
               | ch4s3 wrote:
               | Sorry, here's the correct link https://obgyn.onlinelibrar
               | y.wiley.com/doi/abs/10.1111/1471-0...
        
               | ch4s3 wrote:
               | I've never read the Chinese Suihua cohort study so I'm
               | not going to speculate or comment on it.
               | 
               | I think "in the last few generations" is a little
               | speculative. There's strong evidence for epigenetic
               | changes being passed from parents, but going further back
               | the evidence is much weaker.
               | 
               | > what issue do you take with the Dutch hunger study
               | 
               | It's a really narrow study of a rather genetically
               | homogeneous group picked from a really small geographic
               | area and it has all of the issues of any retrospective
               | study. The outcome could just be random chance. If you
               | look at any small closely related group you're just going
               | to find some sort of weird clustering, even if it varies
               | in that group. If similar epigenetic markers showed up in
               | other populations with similar well documented
               | circumstances it would be stronger.
        
               | mikhailfranco wrote:
               | The other cohort mentioned is Overkalix:
               | 
               | https://en.wikipedia.org/wiki/%C3%96verkalix_study
        
           | biophysboy wrote:
           | The basic idea is that genome modifications can be inherited
           | with the genome. Methylation is one example; histone mods are
           | another. If you want specific examples, I'd recommend
           | focusing on a specific type of modification and searching
           | "fill-in-the-blank inheritance", to avoid the more dramatic
           | pop science.
        
           | directevolve wrote:
           | I'm in a comp bio PhD studying epigenetics in development and
           | disease. Epigenetics can be thought of as the set of
           | biochemical mechanisms other than the linear sequence of DNA
           | that store and respond to information to control cell
           | behavior. This is how normal development from a single zygote
           | to an adult organism is controlled, why cells vary so much
           | despite having (mutations/mosaicism aside) the same DNA, how
           | cells respond to changing biochemical conditions, and where
           | cancer comes from.
           | 
           | The classic example of epigenetics - of stable information
           | transfer between cell generations not based on DNA sequence -
           | is methylation of cytosines. Here's the simplified version.
           | As you know, the DNA is based on ACTG. When you have a CG,
           | the C can be methylated, which means an extra carbon is
           | attached at a specific position on the molecule. That extra
           | carbon gets 'copied' when the DNA is duplicated during
           | mitosis and gets passed to the daughter cells. Yet it can be
           | added or erased during the cell's lifetime. It typically
           | works to block proteins responsible for transcribing genes
           | into mRNA from binding to the gene, so the gene is silenced
           | when it is methylated. This gives a way to transmit patterns
           | of gene expression across generations of cells.
           | 
           | This mark is extremely well-studied and understanding
           | everything about DNA methylation is beyond this humble PhD
           | student. But there are also extremely mechanisms for erasing
           | and/or resetting certain aspects of cell state during mitosis
           | or meiosis, including RNA, the proteome, and methylation
           | state. We can't take it for granted that just because there's
           | a mechanism by which biochemical information could be
           | transmitted that it actually is (or that it isn't).
           | 
           | A common source for the idea of intergenerational trauma
           | being supported by epigenetic evidence is the Dutch hunger
           | winter [1]. The idea is that an experience that parents had
           | in utero seems to have had an effect on the physical
           | development of their children, in a way that's specific to
           | parental sex. I'm willing to say "sure, that effect could be
           | real and there could be an epigenetic explanation." But AFAIK
           | we don't know specifically what that hypothetical mechanism
           | would have been.
           | 
           | Note that the bod(y|ies) of the mother and child are
           | interchanging material and engaging in biochemical crosstalk
           | constantly during gestation, so there is abundant opportunity
           | for environmental influences on the mother to have lifelong
           | impacts on the child. Since the child's body will in turn
           | engage in the same 'dialog' with the child's own children
           | during fertilization and gestation, it's entirely possible
           | for environmental influences on generation 1 to impact
           | generation 3 as mediated by generation 2 via an in utero
           | exposure.
           | 
           | All that said, I have a lot of uncertainty about what our
           | priors ought to be on how important such hypothetical
           | mechanisms might be. I think that in the coming decades,
           | we'll make huge progress in understanding development and
           | disease within an individual's body through an epigenetic
           | lens. We will probably also see some interesting controlled
           | experiments on "epigenetic inheritance" using short-lived
           | model organisms, such as fruit flies or worms. Possibly we
           | will collect enough epigenetic information in large-scale
           | biobanks over 20-40 years that we can get a more detailed
           | understanding of possible epigenetic inheritance mechanisms
           | in humans, but these assays are currently quite expensive,
           | and moreover there's no single measure applicable to an
           | individual person, since the whole point of epigenetics is
           | that the state varies across cell and tissue type.
           | 
           | [1] https://www.ohsu.edu/school-of-medicine/moore-
           | institute/dutc...
        
             | ch4s3 wrote:
             | The cohort studies around the Dutch Hunger Winter are
             | really interesting but it's a huge leap to generalize from
             | maternal starvation during gestation have all kinds of
             | effects to some fanciful ideas of inherited trauma writ
             | large.
        
         | ChuckMcM wrote:
         | Yeah but so many people _want_ to believe this idea. Consider
         | all the history of people of  "royal blood" as if that endeared
         | them with the knowledge and skills of ruling. There is a whole
         | industry that plays to this desire of people to "know". From
         | palmistry to genetic memory, they are all bonkers.
        
           | 47282847 wrote:
           | I can not look into my genes so I know nothing about that,
           | but what I can say with confidence is that trauma therapy
           | continues to fundamentally change how I judge, act and react,
           | and has deeply positive effects on all my relationships. I
           | can totally see how that positively influences how my
           | children will develop. That aspect of "passing on trauma" is
           | very real. I now stay calm and regulated in most stressful
           | situations, and in the few cases where I overreact I know how
           | to and I have the ability to (!) make up for it later and
           | correct my mistakes. And use the trigger to further heal past
           | pain.
        
             | rahimnathwani wrote:
             | The article is about genetic inheritance, not about
             | inheritance in general.
        
           | 0xcde4c3db wrote:
           | Definitely. People want to believe it so badly that they'll
           | just throw all logic out the window. I can't find it with a
           | cursory search, but I recall one case in which a person
           | allegedly inherited a fear of drowning via "genetic memory"
           | from her _uncle_ who drowned shortly before she was born. It
           | 's essentially "psychic medium" bullshit with a veneer of
           | pseudobiology. But hoo boy, does that ever play well.
           | 
           | It's one thing to suggest that psychological or metabolic
           | stress could affect the dynamics of DNA methylation in a way
           | that crosses generational boundaries. It's quite another to
           | identify those inherited dynamics as "memories".
        
             | jraph wrote:
             | Why yes, this stuff jumps _diagonally_. That 's called an
             | epigenic memory cross-transfer. It also works backwards and
             | if one of the being is dead, and affects you from your
             | birth even if the event had not happened yet at the time.
             | Retcon Epigenetics 101.
             | 
             | :-)
        
           | Cthulhu_ wrote:
           | It's easy to mistake upbringing with something inherited, or
           | culture and behaviour with familial / race / appearance. I'm
           | sure THAT part is partially inherited (same with the pattern
           | recognition mentioned above).
        
         | mech422 wrote:
         | I always wonder how animals that aren't raised by parents know
         | various things...like why do predators know bright colors are a
         | 'warning' if they don't have parents to teach them? How do
         | spiders know what their web 'should' look like (spider webs
         | come in multiple styles...)
         | 
         | People say 'instinct' by never mention what that means or how
         | it works :-P
        
           | AQuantized wrote:
           | There's an idea of 'fixed action patterns' where certain
           | behaviors are encoded in the neurology of an animal, and
           | triggered by certain stimulus.
           | 
           | For spiders then there is an action pattern that upon certain
           | stimulus they will use their spinnerets begin forming a web,
           | first placing anchor points and gradually building it up with
           | radial threads and spiral. The exact behavior differs by
           | species such that they have different resulting patterns. It
           | seems possible that there is an element of 'learning' beyond
           | the basic pattern as well, even in seemingly very simple
           | animals.
           | 
           | I doubt the spiders have a mental model of what their web
           | looks like as such, it's more evolutionary driven genetic
           | behavior, a particular neuronal pattern encoding the action
           | sequence rather than an underlying fundamental understanding.
        
             | mech422 wrote:
             | Thanks!
             | 
             | >For spiders then there is an action pattern that upon
             | certain stimulus they will use their spinnerets begin
             | forming a web, first placing anchor points and gradually
             | building it up with radial threads and spiral.
             | 
             | I can sorta understand stimulus causing them to start
             | making a web (sorta like stimulating a mammary can cause
             | lactation) - but how do it 'know' to use a radial pattern
             | rather then ah-hoc mess the black widows on my porch make?
             | The 'ad-hoc' pattern seems like it would be more 'likely'
             | then a nice pattern? Overall, I guess it just seems like a
             | rather complex pattern/behavior?
             | 
             | Also, I guess I have a more basic question of 'what is
             | instinct' if its not some sort of 'memory'? People seem to
             | have an 'instinct' of the mechanics of throwing a ball, yet
             | we have wildly different abilities with regards to
             | accuracy, 'form', distance/speed (due to muscalture?) - it
             | just seems like we have an 'instinct' for the 'simple'
             | mechanical movements but not for the more complex behavior
             | like throwing a ball to hit a target ?
             | 
             | Thanks again!
        
               | AQuantized wrote:
               | The stimulus starts the fixed action pattern, but that
               | action pattern includes the behavior to make the entire
               | web, not just the start off the process. Different
               | species of spider have different fixed action patterns
               | (and different neurology underlying that, and different
               | DNA underlying that neurology).
               | 
               | I think throwing a ball is more learned, although some
               | behaviors like grasping the ball may provided a fixed
               | action foundation on which higher order learning builds.
               | Baby humans have a grasp reflex that works in a similar
               | way to the fixed action pattern described, but with a
               | simpler action sequence. If you touch the palm of a
               | toddler, they will instinctively tightly grasp. It's
               | interesting that the grasp reflex disappears around 5
               | years old, so the fixed neuronal pattern is subsumed by
               | higher order learned behavior.
        
               | mech422 wrote:
               | >>includes the behavior to make the entire web, not just
               | the start off the process.
               | 
               | Thats where I get stuck..the 'behavior' has to account
               | for different sizes of webs (the spider might be in a
               | tight space, or a more open space), etc.
               | 
               | That just seems like an incredibly complex behavior to
               | encode...Cells are supposedly 'simple' organisms but they
               | manage to create/manage such complex behaviors...it's
               | mind blowing..
               | 
               | Thanks!
        
               | quectophoton wrote:
               | > I can sorta understand stimulus causing them to start
               | making a web (sorta like stimulating a mammary can cause
               | lactation) - but how do it 'know' to use a radial pattern
               | rather then ah-hoc mess the black widows on my porch
               | make? The 'ad-hoc' pattern seems like it would be more
               | 'likely' then a nice pattern? Overall, I guess it just
               | seems like a rather complex pattern/behavior?
               | 
               | My guess: It "just feels right".
               | 
               | In the beginning (?), the species didn't have any
               | "preference" and just did whatever. Some species cut the
               | pizza in circles (as in, cutting out a circle from
               | _inside_ the pizza, leaving a donut-shaped pizza), others
               | cut squares, others cut weird shapes, etc. All over the
               | place.
               | 
               | Over time, those predisposed to cutting the pizza in a
               | straight line, from border to border, passing through the
               | center, began to survive slightly longer than the rest
               | (for some unknown reason), becoming the dominant
               | predisposition. To anyone born since then, it just felt
               | right to cut the pizza that way. Not passing through the
               | center of the pizza was just weird. And stopping a cut
               | midway, without going all the way through, was also just
               | weird.
               | 
               | At that point the amount of cuts still varied though, so
               | it was all over the place. Some cut it in half, other
               | made 2 cuts (4 slices) but they were in ugly 20deg angles
               | (so 2 huge slices and 2 small slices), others made
               | hundreds of cuts so each piece was tiny and was annoying
               | to eat, stuff like that.
               | 
               | Over time, those who preferred to cut the pizza in 90deg
               | angles started to survive slightly longer, and over time
               | became the dominant predisposition.
               | 
               | And so on and so on. With these learnings it was becoming
               | easier for people to make pizza ("find food"). Pizza
               | sizes increased, and so did the amount of people sharing
               | a single pizza. Making it easier to attract others, and
               | share a pizza with them. Meeting more people makes it
               | slightly more likely to find a life partner.
               | 
               | Time passed, same old song and dance. Now all pieces must
               | be symmetrical. It was the most fair way to share. Not
               | doing it this way meant the one doing the cuts was evil
               | and must be avoided.
               | 
               | Current situation: Most people cut the pizza in 8 equal-
               | ish slices because it just feels right to do it that way.
               | Those who don't do it that way might still reproduce, but
               | are slightly more likely to be avoided because they are
               | weirdos. They are also slightly less able to get food,
               | because nobody wants to share their pizza with those
               | weirdos, so they are slightly more likely to starve due
               | to being unable to "attract" food.
               | 
               | In that parallel universe, someone named 224hcem asks:
               | 
               | > But how do they "know" to cut the pizza in 8 equal
               | slices rather than the ad-hoc mess the teenagers next
               | door make with their microwaved pizza? Overall it's way
               | more effort to try to make all pieces nice and equal, and
               | the movements have to be more precise meaning the brain
               | calculations are more complex compared to just winging
               | it.
        
               | mech422 wrote:
               | I guess I just get hung up on how such 'simple' cells can
               | encode such complex behaviors...
               | 
               | Thanks
        
               | fsn4dN69ey wrote:
               | You can basically think of insects like this as organic
               | ASICs. Input in, output out. It's a biological circuit
               | that just has a raw response that's hardcoded in. Kind of
               | like asking how does a computer know to do "MOV". It's
               | baked in to the circuit. Do trial and error trillions of
               | times and some of the circuits end up functioning and
               | survive.
        
               | mech422 wrote:
               | It just seems like a lot of behaviors are closer to full
               | blown programs rather than a single instruction :-)
               | 
               | And the more complex the behavior the more it blows my
               | mind :-D
               | 
               | Thanks!
               | 
               | Thanks for the link below - it was pretty neat :-D
        
               | fsn4dN69ey wrote:
               | Yeah, the depth of biology is insane. You can even look
               | closer to home - humans have built in visual mappings for
               | specific shapes. https://www.quantamagazine.org/a-math-
               | theory-for-why-people-...
        
               | sliken wrote:
               | It's been awhile, but I was reading about black widows.
               | Apparently the better fed they are, the worse the web, so
               | they don't over feed.
               | 
               | A chaotic web is a sign that the black widow spider is
               | well fed and not hungry.
        
               | mech422 wrote:
               | Huh...I didn't know that...the lil S.O.B.s on my porch
               | must be really well fed - the webs are everywhere :-D
               | 
               | Thanks
        
               | sliken wrote:
               | I'm pretty sure it's generally 1 spider per web, and I
               | thought blackwidows (assuming they are still alive) take
               | down the webs when done. So presumably you have quite a
               | few spiders.
               | 
               | In any case here's a discussion of said paper.
               | 
               | https://www.nationalgeographic.com/science/article/death-
               | tra....
        
             | hammyhavoc wrote:
             | Adjacent, and you've probably seen it before, but you and
             | others might be interested: https://en.wikipedia.org/wiki/E
             | ffect_of_psychoactive_drugs_o...
             | 
             | This is fascinating stuff.
        
               | mech422 wrote:
               | LOL - yeah, I remember seeing the spider ones and going
               | "probably better then I could do stoned" :-P
        
           | euroderf wrote:
           | Sidenote: My brother the biologist tells me that cats do not
           | instinctively understand that heights can be dangerous; they
           | have to learn it by trial & error.
        
             | mech422 wrote:
             | Wow - that surprises me - I would have thought heights
             | would be an 'instinct' thing - like water (animals know to
             | try not to drown...)
        
               | quectophoton wrote:
               | To be fair, animals who _don 't_ try to avoid drowning,
               | are more likely to drown before being able to reproduce.
               | Probably even by trying to drink water or wash their
               | face, since both mouth and nose usually lead to lungs (I
               | bet there exists some weird animal where that's not the
               | case).
               | 
               | Also, humans don't instinctively understand that fire can
               | be dangerous, so there's that.
        
               | mech422 wrote:
               | Heh
               | 
               | I didn't realize people don't have an instinct about
               | fire. I always thought kids touching hot stoves/fire was
               | because their hands touched it before their brains
               | registered 'hot! ouch!'
        
               | randomdata wrote:
               | Nine lives coupled with always landing on their feet
               | didn't leave much evolutionary pressure to be afraid of
               | heights.
        
               | mech422 wrote:
               | LOL :-)
        
           | Llamamoe wrote:
           | Most DNA is non-coding and encodes tweaks to which genes are
           | expressed where and how. The same way evolution evolved
           | reliable formation of complex body arrangements out of
           | stochastic molecular processes and variations in gene
           | expression based on location, nearby cells and their own
           | signalling, it's done the same for neurons which are far from
           | a homogenous mixture and thus can learn some
           | things("instinctual behaviour") easier than others, all the
           | way to it happening essentially automatically.
        
             | mech422 wrote:
             | I'm amazed by how cells know what to grow 'into' as well -
             | especially since stem cells seem to be able to grow into
             | just about any body part?
             | 
             | >>and thus can learn some things("instinctual behaviour")
             | easier than others
             | 
             | I don't understand this - Isn't 'instinctual behaviour'
             | something you don't have to learn? Also, I wonder if
             | there's a limit to how complex a behavior can be 'encoded'?
             | like bright colored animals == poisonous. That requires
             | being able to tell a say a toad from a bird, what a color
             | is, what colors = poison, etc? That seems like a pretty
             | complex behavior...Do we have any idea what the limit is
             | for complex behaviors in genes?
             | 
             | Thanks!
        
               | Llamamoe wrote:
               | To be clear, I'm not an expert, but the way I imagine it
               | is as genetically encoded biases to process information
               | differently based on its colour, position, which
               | neuron(s) or receptors it's coming in from, etc. that
               | don't necessarily encode the entire neural circuitry for
               | a behavior, but make it automatically learnable without
               | the need for full-blown experiences, just as a
               | consequence of the neurons developing and being exposed
               | to normal environmental information at all.
        
               | mech422 wrote:
               | I guess I just get floored that such complex behaviors
               | can be encoded. Like how some people seem to 'just know'
               | how to draw and I can't draw a straight line with a
               | ruler...
        
               | Terr_ wrote:
               | > I'm amazed by how cells know what to grow 'into' as
               | well - especially since stem cells seem to be able to
               | grow into just about any body part?
               | 
               | AFAIK the current explanations for this often involve
               | electrical and chemical gradients, along with "timer"
               | cyclic reactions among groups of cells.
               | 
               | A contrived example: Suppose the first progenitor cell
               | buds off two children, where one is set to be "Emit Head
               | signals, flee from Tail signals" and the other is "Emit
               | Tail molecules, flee from Head molecules". These two
               | daughter-lines promptly zip off in opposite directions,
               | and now there's a kind of chemical Head-to-Tail measure
               | in the middle for differently-calibrated cells to arrange
               | themselves on.
               | 
               | Then it buds off some cells that are tuned to create a
               | line in-between the two poles, and those cells
               | generate/follow a certain chemical "beat" in order to
               | subdivide, and if the beat lasts X cycles they create X
               | striped zones, which might become chunks of a spine...
        
               | mech422 wrote:
               | Thing is, it seems to me like some sort of 'master
               | control' needs to know what signals to emit. Which sounds
               | like it has to have a 'blueprint' of what the entire
               | organism should 'look' like?
               | 
               | I always think of some lil control room going "ok..we
               | need a heart and 2 lungs...send out the heart signals,
               | and send out 2 lung signals" (electrical or chemical or
               | whatever the signals are)
               | 
               | Just amazing such 'simple' organisms manage to co-
               | ordinate all this stuff...
               | 
               | Thanks
        
               | Terr_ wrote:
               | Homeobox genes [0] are relevant when it comes to pretty
               | high level "heads go on that end, butts go on that end"
               | stuff.
               | 
               | There's also this parody video of _Despacito_ [1] that
               | may be, er, educationally amusing.
               | 
               | [0] https://en.wikipedia.org/wiki/Homeobox
               | 
               | [1] https://www.youtube.com/watch?v=ydqReeTV_vk
        
           | qarl wrote:
           | > People say 'instinct' by never mention what that means or
           | how it works :-P
           | 
           | Have you never been afraid of spiders or snakes?
           | 
           | https://www.cbs.mpg.de/Fear-of-spiders-and-snakes-is-
           | deeply-...
        
         | biotinker wrote:
         | I don't see any connection between the Guardian and the
         | recovered memory movement.
         | 
         | Throughout this thread you have a bit of an insistence on
         | narrowly defining memory in terms of the brain, i.e. memories
         | that people have.
         | 
         | In the field of epigenetics, and in computer science, and other
         | areas, "memory" more broadly means a system of encoding
         | information. Which is what happens here, when methyl groups
         | physically bind to an adenine or cytosine molecule, like
         | flipping a bit.
         | 
         | It's incorrect to call information stored in epigenetics
         | "memories", but it's fine to call it "memory". I forgive the
         | article for doing this as it's written for consumption by the
         | broad public, and it's illustrative of the overall point if not
         | literally correct.
         | 
         | FYI, the author is a respected neuroscientist:
         | https://en.wikipedia.org/wiki/Hannah_Critchlow
        
           | ch4s3 wrote:
           | > I don't see any connection between the Guardian and the
           | recovered memory movement.
           | 
           | It's a comparison.
           | 
           | Respected or not she's making the argument the "the body
           | keeps the score," which is redolent of the discredited book
           | of the same name.
        
             | mrcartmeneses wrote:
             | > Respected or not she's making the argument the "the body
             | keeps the score," which is redolent of the discredited book
             | of the same name.
             | 
             | The body keeps the score is discredited?
        
               | ch4s3 wrote:
               | Yes, the book is by one of the original nut bags behind
               | the recovered memory craze. Here[1] is an academic
               | publication talking about the problems with it.
               | 
               | [1]https://pubmed.ncbi.nlm.nih.gov/16483114/
        
       | humansareok1 wrote:
       | Can memories be explicitly encoded in genes? If not then no. End
       | of the story.
        
         | ch4s3 wrote:
         | To the best of my understanding, no and I'm aware of any
         | proposed mechanism.
        
           | alkonaut wrote:
           | Isn't the article describing in depth how an experiment
           | showed it possible or did I completely misread it? It even
           | explained the mechanisms behind it?
        
             | ch4s3 wrote:
             | The article glosses over some details of a decade old
             | study, that might have maybe shown that some types of
             | conditioning using electrical shock might have epigenetic
             | effects that persist in gametes and effect later behavior.
             | The study attempts to show it indirectly and hand waves at
             | the mechanisms. It doesn't test for DNA methylation or
             | anything similar.
        
               | oa335 wrote:
               | They did test for and find hypomethylation.
               | 
               | It's mentioned in the article here: > How had this
               | happened? The team discovered that the DNA in the
               | grandfather mouse's sperm had changed shape. ... The gene
               | for this olfactory receptor had been demethylated
               | (chemically tagged), ...
               | 
               | As well as in the abstract of the linked study:
               | 
               | > Bisulfite sequencing of sperm DNA from conditioned F0
               | males and F1 naive offspring revealed CpG hypomethylation
               | in the Olfr151 gene.
               | 
               | https://pubmed.ncbi.nlm.nih.gov/24292232/
        
               | ch4s3 wrote:
               | I must have missed that reading the study, and that
               | certainly is a little more compelling. I'm still very
               | skeptical about the way the guardian article presents the
               | claims, and the lack of any mention of follow up work
               | since the decade old study.
        
           | amelius wrote:
           | From TFA:
           | 
           | > The study made use of mice's love of cherries. Typically,
           | when a waft of sweet cherry scent reaches a mouse's nose, a
           | signal is sent to the nucleus accumbens, causing this
           | pleasure zone to light up and motivate the mouse to scurry
           | around in search of the treat. The scientists exposed a group
           | of mice first to a cherry-like smell and then immediately to
           | a mild electric shock. The mice quickly learned to freeze in
           | anticipation every time they smelled cherries. They had pups,
           | and their pups were left to lead happy lives without electric
           | shocks, though with no access to cherries. The pups grew up
           | and had offspring of their own.
           | 
           | > At this point, the scientists took up the experiment again.
           | Could the acquired association of a shock with the sweet
           | smell possibly have been transmitted to the third generation?
           | It had. The grandpups were highly fearful of and more
           | sensitive to the smell of cherries.
        
             | ch4s3 wrote:
             | I read the underlying study. It's pretty shy on
             | experimental details, and while an epigenetic change is the
             | possible mechanism they don't directly show that. It's also
             | a huge leap from the guardian article's claim that memories
             | are inherited.
        
               | moralestapia wrote:
               | They're not claiming that, though.
        
               | ch4s3 wrote:
               | The article includes this passage:
               | 
               | > Might this new understanding increase our capacity for
               | self-awareness and empathy? If we can grasp the potential
               | impact of our ancestors' experiences on our own
               | behaviour, might we be more understanding of others, who
               | are also carrying the inherited weight of experience?
               | 
               | They are literally refereeing to the concept of inherited
               | trauma and inter-generational memory throughout the
               | piece. It's a favorite hobby-horse of the guardian and
               | while they are somewhat subtle here and dress it up by
               | picking a very old study, they are in fact talking about
               | the kind of ideas appearing in popular self help books
               | like The Body Keeps the Score, and other things in their
               | orbit. The author of the article in question is hawking a
               | similar book on the guardian's books platform.
        
               | moralestapia wrote:
               | It has a question mark.
               | 
               | Claims don't have question marks.
        
               | ch4s3 wrote:
               | The whole article is full of similar statements, I just
               | found that short paragraph illustrative.
        
               | moralestapia wrote:
               | Well, it definitely wasn't illustrative as a claim.
               | 
               | But since there are so many such statemetns, feel free to
               | post a few examples.
        
               | ch4s3 wrote:
               | This is pretty misleading:
               | 
               | >Scientists working in the emerging field of epigenetics
               | have discovered the mechanism that allows lived
               | experience and acquired knowledge to be passed on within
               | one generation, by altering the shape of a particular
               | gene.
               | 
               | Also pretty debatable:
               | 
               | > or the trauma inflicted on your grandfather when he
               | fled his home as a refugee, might go on to shape your
               | parents' brains, their behaviours and eventually yours.
               | 
               | Or a reference to the thoroughly academically panned The
               | Body Keeps the Score:
               | 
               | > It's not just our body that keeps the score but our
               | very genes.
        
         | keithalewis wrote:
         | But never the end of clickbait.
        
         | dmd wrote:
         | Your understanding is half a century out of date.
         | https://en.wikipedia.org/wiki/Epigenetics
         | 
         | Note that I'm not claiming here that memories can be encoded in
         | genes; I'm also not making a strong claim here that memories
         | can be encoded epigenetically!
         | 
         | What I am arguing against is the claim that the only _possible_
         | method of transmission of traits is through DNA, which is what
         | parent comment said, and has been out of date for quite some
         | time.
        
           | humansareok1 wrote:
           | Oh yeah so you want to explain how Epigenetics can transfer
           | the memory of my Grandfathers 17th Birthday Party to my
           | brain?
        
             | jvanderbot wrote:
             | ELI5 attempt:
             | 
             | Your genes are a recipe book, not a blueprint. What recipe
             | is chosen is based somewhat on environmental effects. When
             | you reproduce, you pass on the book + the earmarks on the
             | pages.
             | 
             | In your comment, the word "Explicitly" is the controversial
             | part. Of course a memory cannot be _explicitly_ (like .mp4?
             | lol) encoded in genetics. But effects pass on, or so says
             | the field. It's the same as how the word "Memories" in the
             | title is doing a lot of hand-wavey hype generation. Can I
             | share a password or birthday party during intercourse? Of
             | course not.
        
               | humansareok1 wrote:
               | >Of course a memory cannot be _explicitly_ (like .mp4?
               | lol) encoded in genetics.
               | 
               | Indeed so the answer to the question: Can you inherit
               | memories from your ancestors? Is No. Full stop.
               | 
               | You want to talk about how the vibes during your
               | grandparents lives affected some obscure part of your
               | parents health then ok. But these things are completely
               | different.
        
               | moralestapia wrote:
               | >Can you inherit memories from your ancestors? Is No.
               | Full stop.
               | 
               | With our current knowledge, we cannot either prove or
               | disprove this.
        
               | jvanderbot wrote:
               | Yeah - so, if you want to be right about your takedown of
               | the title using narrow interpretations of "memories", you
               | probably can be.
               | 
               | But if you want a nuanced discussion of the article, we
               | should soften the gaze a little. That's all I'm saying.
        
             | francisofascii wrote:
             | Maybe your grandfather had chocolate cake at his party but
             | it turned out bad and people got sick. Now today you has an
             | unexplained aversion to chocolate cake.
        
           | Angostura wrote:
           | So, can you give any evidence or even point at a suggestion
           | that inheritable epigenetics can encode inheritable memories?
        
             | moralestapia wrote:
             | Not GP, but keep in mind that absence of evidence is not
             | evidence of absence.
             | 
             | We would still be cavemen with that attitude.
        
             | biophysboy wrote:
             | Its not a brain memory. The argument is that epigenetic
             | modifications can be inherited and thus the ancestor's
             | environment is "remembered". As for how long it lasts and
             | how much the memory is attenuated, well, that's another
             | matter.
        
         | passion__desire wrote:
         | "Nobody would suppose that the fact that human beings
         | everywhere always throw their spears pointy-end first shows
         | that there must be a gene for a pointy-end-first instinct." -
         | Daniel Dennett.
         | 
         | Counterpoint : "But, as Weiss discovered in a 2008 study, moths
         | and butterflies can retain memories from their time as
         | caterpillars, suggesting that the creatures' nervous system
         | remains during the transformation into a butterfly."
        
       | HPsquared wrote:
       | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923835/
       | 
       | "Parental olfactory experience influences behavior and neural
       | structure in subsequent generations" (2014)
        
         | frutiger wrote:
         | > "Parental olfactory experience influences behavior and neural
         | structure in subsequent generations"
         | 
         | "[...in mice]"
        
           | HPsquared wrote:
           | Yes, but the underlying mechanisms behind brains, neurons,
           | cells, DNA etc. aren't going to be so different.
        
             | frutiger wrote:
             | That's really not always true. And it's disingenuous to so
             | unequivocally write the title of a paper about mice when
             | the headline article is about humans.
        
               | HPsquared wrote:
               | The article talks about the mouse research, I'm giving a
               | link so people can read something other than a Guardian
               | article and judge for themselves. Fair enough mice are
               | different to humans but they're not exactly lobsters.
               | (Edit: although if a similar mechanism was found in
               | lobsters I would take that as evidence the phenomenon
               | being widespread. It's not ethically feasible to conduct
               | this experiment on human subjects)
        
           | francisofascii wrote:
           | Since human brains and DNA are more complex it is reasonable
           | to suspect the generational transference to be greater than
           | in mice.
        
       | prokopton wrote:
       | Fire up the Animus.
        
       | hliyan wrote:
       | Interesting! So basically: smell followed by electric shock (or
       | some other painful stimuli) -> demethylation of (already present,
       | but dormant?) gene that connects relevant olfactory receptor to
       | the amygdala?
        
       | taraparo wrote:
       | When memory is made by modifying DNA according to
       | https://www.nature.com/articles/d41586-024-00930-y and we inherit
       | DNA, then we probably also somehow inherit some form of memories.
        
       | jappgar wrote:
       | "Thus, when you and I, asleep or dozing off to sleep, fall
       | through space and awake to sickening consciousness just before we
       | strike, we are merely remembering what happened to our arboreal
       | ancestors, and which has been stamped by cerebral changes into
       | the heredity of the race."
       | 
       | https://www.gutenberg.org/files/310/310-h/310-h.htm
        
       | zarmin wrote:
       | See also: Rupert Sheldrake Morphic Resonance
       | 
       | https://youtu.be/jq1Z--HQp5k?t=9
        
       | fire_lake wrote:
       | Funnily this is an idea that both the far right and the far left
       | tend to like.
       | 
       | The far right to suggest that there is a sort of cultural memory
       | that immigrants can never integrate with.
       | 
       | The far left to suggest a kind of cultural trauma that requires
       | affirmative action.
        
         | Cthulhu_ wrote:
         | I'm not sure where you got the take that the left thinks of it
         | as trauma; it's consequent events (e.g. your ancestors could
         | not get an education, job, and/or buy a house because of racism
         | -> you did not benefit from generational wealth even though
         | there is now less racism).
         | 
         | I'm also not sure where you get the far right idea from; I
         | don't think they believe in "a sort of cultural memory", it's
         | just culture, nothing woo about it.
         | 
         | TL;DR it feels like you're misrepresenting political sides to
         | try and make this article about politics.
        
           | Unbefleckt wrote:
           | I only knew this existed because of the "left" take with
           | regards to people descended from slaves (black only of
           | course)
        
             | qarl wrote:
             | As someone on the left - there's nothing "woo woo" about
             | systemic racism.
             | 
             | The single greatest indicator of a person's financial
             | success is that of their parents. And that simply repeats
             | generation after generation.
             | 
             | There's nothing magical about it.
        
               | nsriv wrote:
               | Exactly this. My response is usually just asking if they
               | believe in compounding interest. It's the same concept,
               | but with those farther up the curve justifying
               | themselves.
        
               | randomdata wrote:
               | Hence the "woo woo". The promise of delivery of value in
               | the future, of which compound interest is a part of, is
               | an invented construct that hinges entirely on people
               | believing it to be the way things are. If people stopped
               | believing, it would all cease to exist. There is no
               | fundamental property of the universe that makes it so. It
               | is merely religion.
        
               | qarl wrote:
               | The fact that successfulness of parents predicts
               | successfulness of children is "woo woo"?
               | 
               | I hate racism. It makes people dumb.
        
               | randomdata wrote:
               | The fact _ors_ that successfulness of parents predicts
               | successfulness of children is  "woo woo".
               | 
               | It is not some fundamental property of the universe. It
               | is that way only because people believe it to be the way
               | things are. We could stop believing. It is just religion.
               | But it seems nobody wants to, "the left" included.
               | 
               | Why is that? Because they are a benefactor from it?
               | Because, as you suggest, their racist ways have "made
               | them dumb"? The youth population - those able to offer
               | the most future value and thus responsible for
               | maintaining the status quo - by and large "lean left". It
               | is not a "those other guys are to blame" situation.
        
               | qarl wrote:
               | > It is not some fundamental property of the universe.
               | 
               | LOL. You don't believe in social patterns?
               | 
               | Ok, well, you might be the only one. I hope you don't
               | invest in stocks or try to start your own company. Or
               | have friends.
        
               | randomdata wrote:
               | I don't have beliefs, but I do acknowledge your point
               | that actions speak louder than words. It is easy to say
               | you are racist, but hard to do something about it, and
               | social pattern data indicates that people are lazy and
               | racist and therefore won't do anything[1] about it.
               | 
               | [1] Posting silly comments on the internet for the sake
               | of entertainment is not doing something as it pertains to
               | this.
        
               | qarl wrote:
               | Yeah... you take care now.
        
               | randomdata wrote:
               | Is there some concern that Hacker News is going to fall
               | out of care? Or what do you mean by this?
        
             | exe34 wrote:
             | could you give an example?
        
         | qtplatypus wrote:
         | The left don't think that trauma can be inherited. They think
         | that wealth and social standing can. If your parents have money
         | they can use their wealth to make it easier for you to have
         | money
         | 
         | If your parents are poor (perhaps due to racism) then you will
         | live in a poor area with worse schools, possibly contaminated
         | with pollution, subject to higher insurance and basic costs.
         | 
         | This doesn't require magic ancestral memories it just requires
         | ecomonics.
        
           | shagie wrote:
           | > The left don't think that trauma can be inherited.
           | 
           | The epigenetic reaction to trauma is something that may be
           | able to be inherited.
           | 
           | Epigenetic transmission of Holocaust trauma: can nightmares
           | be inherited? - https://pubmed.ncbi.nlm.nih.gov/24029109/
           | 
           | Study finds epigenetic changes in children of Holocaust
           | survivors - https://www.research.va.gov/currents/1016-3.cfm
           | 
           | How Parents' Trauma Leaves Biological Traces in Children -
           | https://www.scientificamerican.com/article/how-parents-
           | rsquo...
           | 
           | Mechanisms of Epigenetic Inheritance in Post-Traumatic Stress
           | Disorder -
           | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10817356/
           | 
           | (Not trying to pose this as a left/right thing - but rather
           | "this is a thing" - and these aren't memories but rather the
           | result of epigenetic changes to the expression of hormones
           | and neurotransmitters that may be able to be passed from
           | mother to child and exhibit differences in how one reacts to
           | certain stimuli)
        
         | CyberDildonics wrote:
         | I've never heard any of these ideas. The question in the title
         | is nonsense and you are skewing and distorting other ideas into
         | more nonsense to make something that is already ridiculous
         | political.
        
       | hellodang_ wrote:
       | Yeah, nobody here knows a single thing they're talking about.
        
       | francisofascii wrote:
       | This is analogous to when we inherit an old application without
       | the git history and the original developers are long gone. Our
       | instincts are a bunch of logic rules encoded into our DNA like
       | "If you see a python snake, run away".
        
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