[HN Gopher] Sleep deprivation disrupts memory
       ___________________________________________________________________
        
       Sleep deprivation disrupts memory
        
       Author : sabrina_ramonov
       Score  : 178 points
       Date   : 2024-06-14 14:39 UTC (8 hours ago)
        
 (HTM) web link (www.nature.com)
 (TXT) w3m dump (www.nature.com)
        
       | k1ck4ss wrote:
       | now I feel very bad about going to sleep between 11PM and 1AM and
       | getting up between 5AM and 6AM for many many years now.
        
         | failuser wrote:
         | Why? Do you experience memory issues? If you can do that for
         | years and not go insane or break down you must be built
         | different. I know people like that and envy them, but this is
         | not typical.
        
           | sethammons wrote:
           | Since I became a sleep maintenance insomniac (I fall asleep
           | fine but wake up 5hrs later and generally can't fall back
           | asleep), my memory has gone from phenomenal to abysmal. I
           | struggle to keep things in mind. More than ever, I rely on
           | notes and reminders
        
             | JohnBooty wrote:
             | That seems like possibly the hardest kind of insomnia to
             | treat.
             | 
             | Is there any treatment for this specific kind of insomnia?
        
               | SoftTalker wrote:
               | When that happens to me it's often because I'm ruminating
               | about something, can't get it out of my mind and relax.
               | If that's what's keeping you up, CBT (cognitive
               | behavorial therapy) techniques can help to stop that
               | thought pattern, or just taking some daily action (any
               | concrete action besides just turning it over in your
               | mind) towards resolving the thing you're thinking about
               | can help.
               | 
               | White noise sometimes helps me sleep too, especially
               | after waking up in the middle of the night.
        
               | eggdaft wrote:
               | My theory is this is cause by stress hormones.
               | 
               | You can get to sleep because you're so damn exhausted,
               | but you wake up as soon as you're physically able because
               | of the hormones.
               | 
               | The answer is exercise. Aerobic and weights. Three times
               | a week minimum. And for a good amount of time.
        
             | weeksie wrote:
             | I have issues with that as well, started taking magnesium
             | (both normal, elemental magnesium and magnesium
             | l-threonate) and it's made a world of difference for me.
        
           | SoftTalker wrote:
           | > this is not typical
           | 
           | going to sleep between 11PM and 1AM and getting up between
           | 5AM and 6AM is completely typical for a parent with kids in
           | school.
           | 
           | OK 1AM might be pushing it but by the time you eat dinner,
           | help with homework, do chores, get the kids to bed, and take
           | a bit of time for yourself and spouse to decompress, yeah
           | it's easily getting close to 11PM.
           | 
           | Then getting up in time to get dressed, get the kids up, make
           | breakfast, get them to school and get yourself to work,
           | you're probably getting out of bed at aroud 6AM or maybe 7AM
           | at the latest.
        
             | bluefirebrand wrote:
             | Last I spoke to a sleep doctor, I was told that 6-8 hours
             | is enough sleep for a lot of people.
             | 
             | That would mean 11-5 is is actually enough sleep, as is
             | 12-6
             | 
             | So really the problem with these times is only the
             | incidents when staying up to 1am, or when getting up at 5
             | after sleeping at midnight
        
             | failuser wrote:
             | 11PM to 6AM is very different from 1AM to 5AM. Parents of
             | little children who need you to wake up multiple times per
             | night have it worse, IMO. And they often report memory
             | problems and overall mental decline.
        
         | pcurve wrote:
         | If you've been doing if for many years chances are you are one
         | of those folks who don't need as much sleep. Apparently there
         | is genetics involved
         | 
         | https://www.nih.gov/news-events/nih-research-matters/gene-id...
        
           | inanutshellus wrote:
           | It's more concerning if he intentionally deprived himself of
           | sleep during adolescence (e.g. forcibly staying up to play
           | video games), as brain development continues through age 25.
        
       | neilv wrote:
       | The Web page is breaking text selection for me until I disable
       | JS.
        
         | jessetemp wrote:
         | I've had the same problem. In my case it was uBlock hiding the
         | full page cookie dialog but the dialog was still disabling text
         | selection. I really wish websites would just respectfully set
         | the minimum by default and let users opt in to the extra
         | tracking. Then reward those users with internet points or
         | something. People go nuts for internet points.
         | 
         | Regarding the article itself... I always wonder (while laying
         | awake at night) what impact trains have on people's mental
         | health. I'm thankfully not close enough to get woken up by
         | them, but they roll through at like 1am, horns blaring at every
         | hint of an intersection. It's gotta be measurably unhealthy for
         | people living near the tracks
        
         | bowsamic wrote:
         | Please keep comments focussed on the content
        
           | neilv wrote:
           | In case someone wanted to quote text for discussion, now they
           | know to turn off JS.
        
             | bowsamic wrote:
             | It is against the rules here to comment on the form of the
             | website itself. Remain focussed on the content
        
               | neilv wrote:
               | One line, informing people how they can quote text from
               | the article under discussion, vs. a cascade of policy
               | meta-discussion? :)
        
               | bowsamic wrote:
               | Yes
        
       | mattgreenrocks wrote:
       | The mention of deep sleep being necessary to memory formation is
       | especially interesting to me.
       | 
       | I went 5-8 years or so with poor quality sleep. While it is
       | difficult to estimate correctly at home, my Zeo was regularly
       | giving me 15-20m of deep sleep a night and I had a very hard time
       | fixing it. While I performed fine at work, I had a hard time
       | recovering from any sort of physical symptoms (such as tension)
       | and building muscle memory. I certainly felt pretty bad, and it
       | was like things didn't 'stick'.
       | 
       | Nowadays I get 40m on average. Still not great but getting
       | better.
        
         | thesuavefactor wrote:
         | May I ask what you did to improve your deep sleep?
        
           | mattgreenrocks wrote:
           | Hard to pin it on any one thing unfortunately.
           | 
           | I notice it goes up when I'm doing as much as I can of the
           | following: get 20-30m sunlight, talk with friends in person,
           | avoid alcohol, work out, and be more active in building my
           | life (vs having it built for me). Also, doing necessary
           | emotional work with a counselor. All of those IME reduce my
           | low grade anxiety.
           | 
           | It's basically all eating your vegetables stuff. Way more
           | impactful than any supplement or protocol.
           | 
           | N=1 and all that. HTH
        
           | justsomehnguy wrote:
           | Not the OP, but first of all you need enough time. If you
           | constantly have only 5-6 hours of sleep per day then there is
           | nothing what would help.
           | 
           | But if you have enough time than you need to try everything,
           | beginning with air quality, noise and light reduction,
           | bedding quality.
        
           | chasebank wrote:
           | One of the first episodes in the huberman podcast, he
           | references a study where insomnia was cured in 100% of study
           | participants by taking them camping for a week. I think
           | sleeping is like weight loss, it's really simple but people
           | don't want to do what's necessary. Non-sedentary lifestyle,
           | eat right, wake up and go to sleep with sun, don't use
           | electronics, etc.
        
             | vundercind wrote:
             | Only candles after dark (I could read comfortably by two
             | beeswax candles, _very_ dim light compared even to most
             | night lights) and no electronics entirely cured my
             | "insomnia" of decades within a couple days. Go figure,
             | hundreds or thousands of candle-power lighting up whole
             | rooms, and entertainment more compelling than a Roman
             | emperor could command on tap, is extremely bad for sleep.
             | What a surprise.
             | 
             | It's goddamn hard to keep up, though.
        
               | moffkalast wrote:
               | Pro tip: use RGB light strips for room lighting and set
               | them to pure red an hour or two before sleep.
               | 
               | I don't have any trouble sleeping, but that's what I do
               | when someone requires me to suddenly disrupt my sleeping
               | schedule so I can get up at some ungodly early hour and
               | it's the only way I can go to sleep sooner than usual and
               | actually fall asleep.
               | 
               | If you really wanted to do it every day it would make far
               | more sense to automate it and make it gradual to simulate
               | a sunset though.
        
             | vitehozonage wrote:
             | I dislike how you frame it as a personal failure to do what
             | is necessary. It is a societal failure. People may have
             | strong self-control, and want to have completely more
             | primitive lifestyle which would likely improve their mental
             | state, but escaping the industrial society can be simply
             | out of reach for many people. For example if you're poor
             | and born in a city-state you may never even have the
             | capacity to experience camping.
        
               | piuantiderp wrote:
               | Individual problems have individual solutions.
        
               | janalsncm wrote:
               | I disagree that they are individual problems. This isn't
               | Sparta. Many of the negative mental health externalities
               | were created either inadvertently or deliberately to
               | maximize shareholder (read: wealthy, mostly older people)
               | money. It's irresponsible.
               | 
               | And notice I didn't say value. Profiting off of making
               | another person doesn't add value. It extracts it from
               | them, like the scream extractor in Monsters Inc.
        
             | gfourfour wrote:
             | Being outside for an hour during sunset is the best sleep
             | medicine. Don't even have to go camping.
        
             | pseudalopex wrote:
             | Episode 2 was about sleep. But the transcript had no
             | matches for insomnia or camping.[1]
             | 
             | It sounds like a distorted memory of a small study where
             | subjects without sleep disorders slept earlier but not
             | longer or better when camping with natural light and fire
             | only.[2] How long the effect lasted was not studied.
             | 
             | [1] https://www.youtube.com/watch?v=nm1TxQj9IsQ
             | 
             | [2] https://www.cell.com/current-
             | biology/fulltext/S0960-9822(13)...
        
             | consf wrote:
             | > I think sleeping is like weight loss, it's really simple
             | but people don't want to do what's necessary.
             | 
             | What an excellent comparison
        
           | tivert wrote:
           | > May I ask what you did to improve your deep sleep?
           | 
           | I think Steve Gibson (of the Security Now podcast, and
           | absolutely not a doctor), had a "healthy sleep formula" of
           | taking a time release melatonin and a time-release
           | niacinamide supplement, and he claimed his Zeo would register
           | more deep when he took it. I got the impression he thought
           | his own sleep was poor and was trying to fix it, and just
           | talked about his personal project on his podcast.
           | 
           | I tried it, and anecdotally I did feel like I slept deeper.
        
           | radicalbyte wrote:
           | In my case - I've had sleep problems for a decade - it
           | started to improve once my kids stopped waking me up 3-4
           | times a night.
           | 
           | It's still not as good as it was before as I've not been able
           | to get sporting properly and, well, they kids do wake us just
           | not every night anymore.
        
         | alexpotato wrote:
         | There was a post here on Hacker News many years ago about a
         | software developer who became a bicycle messenger.
         | 
         | One point from that post related to this discussion:
         | 
         | "Once I became a bike messenger, I slept like a log for 8 hours
         | every night."
         | 
         | In my own life, having worked both manual, physical labor and
         | been a tech worker, I noticed the following:
         | 
         | - When I worked construction, my body would be exhausted but my
         | mind would be very active when I tried to go to sleep.
         | 
         | - In tech work, it's my mind that is exhausted but my body
         | still has energy
         | 
         | - I've also worked jobs that required a high amount of both
         | physical and mental focus and that's when I usually sleep the
         | deepest.
        
           | jajko wrote:
           | Good old saying - if you work hard manually, rest by doing
           | something mentally challenging, and vice versa. For most of
           | us vice versa applies hard.
           | 
           | I do something every day or evening, even if its just 1.5-2h
           | evening walks. Days I don't do anything are definitely harder
           | to fall asleep, to say the least, and some small achievement
           | is missing.
        
       | yamrzou wrote:
       | > To Diba's surprise, rats that were woken up repeatedly had
       | similar, or even higher, levels of sharp-wave-ripple activity
       | than the rodents that got normal sleep did. But the firing of the
       | ripples was weaker and less organized, showing a marked decrease
       | in repetition of previous firing patterns.
       | 
       | I wonder what would happen if their sleep was disrupted in a
       | "regular" way, thus creating new firing patterns..
        
       | JohnBooty wrote:
       | sleep disruption could be used to prevent          memories from
       | entering long-term storage,          which could be useful for
       | people who have          recently experienced something
       | traumatic,          such as those with post-traumatic stress
       | disorder
       | 
       | This makes sense, but it's hard to see how this would work in
       | practice.
       | 
       | You'd have to induce this sleep deprivation right after the
       | traumatic event. "Sorry you watched your house burn down today
       | with your favorite hamster inside. Here's some modafinil so you
       | won't sleep for two days. It will help you not remember this."
        
         | LoganDark wrote:
         | Bleh. At that point just dissociate. By the time you've got
         | PTSD symptoms it's usually too late to simply prevent memories
         | from being recorded.
        
         | bitcoin_anon wrote:
         | I've always wondered why it's hard to sleep after stress and
         | anxiety. Seems counterproductive, but perhaps it is adaptive.
        
         | 01100011 wrote:
         | > people who have recently experienced something traumatic
         | 
         | As a parent of a 5 month old baby, I can say that nature has
         | already provided a mechanism for this to work. If it were not
         | for the lack of memories of the first 3 months, I would never
         | agree to have another child. It appears evolution has found a
         | use for this quirk of our brains already.
        
         | swatcoder wrote:
         | When you say "in practice", you're thinking of artificially
         | operationalizing it and how one would force that through
         | medication or whatever. Of course that would be hard to
         | sensibly apply in practice! How would you distinguish a
         | traumatizing experience from a manageably negative one in time
         | to formulate a prescription, how would you prescribe
         | wakefulness to someone who didn't seek it themselves, how do
         | you know how much wakefulness is appropriate or what other
         | trouble you might be causing by artificially amplifying it?
         | 
         | But if you step back, the real "in practice" is the thing that
         | bodies already do. Sleep is often a mess after truly shocking
         | experiences, and this mechanism suggests some reason why. For
         | the folk that need scientific studies to justify things that
         | their bodies naturally want to do, this is the study that says
         | it's okay to toss and turn and have weird sleep hours when
         | something bad happens.
        
         | numpad0 wrote:
         | I've attempted that in the past out of similar naive idea. I
         | didn't use any stimulants, just slept on a chair without proper
         | blankets. It did seem to get rid of a lot of unwanted data,
         | though it also posed cognitive penalties, possibly some
         | permanent. I guess it's a last resort option, not something
         | generally recommendable.
        
         | alexpotato wrote:
         | I imagine this correlates somewhat with having children.
         | 
         | It's both a "traumatic" single event (especially for the
         | mother) and also traumatic over time in that your sleep
         | schedule is affected, big changes to your life etc.
         | 
         | People joke that evolution made it so we don't remember how
         | hard it is to have small children but maybe there is some truth
         | to that statement.
        
         | etiam wrote:
         | I severely doubt messing with sense-making and coherence of
         | traumatic episodes is going to prove beneficial.
        
       | 42lux wrote:
       | It feels accurate to me. Whenever I experience a manic episode,
       | my sleep patterns are severely disrupted. Often, I don't sleep at
       | all, or I manage only brief 1-2 hour naps. During these periods,
       | my memories become fragmented and disjointed, making it difficult
       | to recall events clearly. The weeks or even months during these
       | episodes blend together, creating a haze of scattered memories.
        
       | methuselah_in wrote:
       | Because anything on earth requires rest. There is a limit in
       | universe for everything. Now science I know neuron and all. But
       | that's my perception
        
       | jorisboris wrote:
       | Can confirm, ever since having children my memory is pretty poor.
       | Baby brains they call it.
        
       | tantony wrote:
       | I have personally experienced this. I went to a concert in NY
       | while living in the midwest. I was a pretty broke grad-student at
       | the time and hence opted not to get a hotel for the night before
       | the return flight. The concert ended late and we reached the
       | airport by around 3:30 AM for a 7AM flight. I think I took some
       | naps at the gate before the flight and got very little sleep on
       | the flights.
       | 
       | I barely remember anything from that night. The concert itself is
       | mostly blank except for one or two moments. I remember some
       | moments of driving late at night afterwards (getting lost at one
       | point) and having a very late night dinner at an IHOP. I barely
       | remember getting on my connecting flight.
       | 
       | Overall a very surreal experience.
       | 
       | Now I make it a point to get proper sleep on such trips. What is
       | the point of doing these things anyway if we don't get to keep
       | the memories?
        
         | EvanAnderson wrote:
         | I've attempted to use the effect strategically. Not sure if it
         | really worked or not. It's certainly not healthy, and it
         | certainly didn't improve the quality of my work, but I've
         | pushed thru some unpleasant times with an eye toward trying not
         | to form long-term memories by way of sleep deprivation.
        
           | liquid_bluing wrote:
           | Smart move:
           | 
           | Sleep deprivation facilitates extinction of implicit fear
           | generalization and physiological response to fear - PubMed
           | https://pubmed.ncbi.nlm.nih.gov/20889142/
           | 
           | "Clinically, trauma-exposed victims often experience acute
           | insomnia, indicating that such insomnia might provide
           | prophylactic benefits in reducing the development of
           | posttraumatic stress disorder via extinction of the fear-
           | magnifying effects of memory."
        
       | whitehexagon wrote:
       | My dreams are so vivid, and movie like, that I frequently wake up
       | very tired. My memory is shockingly poor, and I have often
       | wondered if it could be connected to poor quality sleep. I also
       | suffer from Aphantasia and suspect the vivid dreams are somehow
       | compensating for that. Mostly it feels like 40years programming
       | has rewired my brain!
        
       | cljacoby wrote:
       | I'm 29 years old, and I have definitely noticed my memory getting
       | worse over the last ~5 years. I've always wondered if this is
       | something to do with sleep deprivation, increased stress from
       | work/school, or just the natural effects of getting older.
        
         | xcv123 wrote:
         | Try doing a 24 hour water fast. It will feel awful during the
         | fast, but you may notice your mind is sharper the next day
         | after a good sleep. Cleans out the cobwebs at a cellular level
         | (autophagy).
         | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106288/
         | 
         | EDIT: I'm getting rate limited so cannot reply to the comment
         | below.
         | 
         | Water fast means only drinking water. Tea or coffee is
         | acceptable if black (meaning without milk or sugar).
         | 
         | "Water fasting is a type of fast during which you're not
         | allowed to consume anything except water."
         | 
         | I would never do a fast that cuts out water/liquids. That is
         | stupid.
        
           | LtWorf wrote:
           | How to die with one simple trick!
        
             | xcv123 wrote:
             | Most people browsing HN would survive 1 - 2 months without
             | food. 24 hours is nothing. Your pot belly has a spare
             | 50,000 calories.
        
               | LtWorf wrote:
               | If you read the comment. He said to "water fast", not
               | just skip food, which would be probably fine.
               | 
               | Also, not everyone is obese. For not obese active people,
               | it might not be the best.
        
             | darajava wrote:
             | Fasting is incredibly well tolerated and good for you. The
             | longest a person has gone without food was about 380 days
             | (Angus Barberi)
        
               | LtWorf wrote:
               | Read before comment? He said to "water fast", which I
               | presume means not drink.
        
           | nine_k wrote:
           | This works, I corroborate.
           | 
           | The problem is not a lack of will or capability to sleep for
           | 8 hours a day. It's usually the lack of ability to allocate 8
           | hours, because of various commitments and other
           | circumstances.
           | 
           | (It's like telling a poor guy to start saving some money.
           | While it's technically absolutely correct, the problem is
           | usually not the lack of the desire to have savings.)
        
           | catoc wrote:
           | "Try doing a 24 hour water fast"
           | 
           | In the referenced study water was available ad libitum.
           | 
           | It's _food_ that was restricted, for 24-48 hours, that
           | promoted beneficial cellular autophagy in mice.
           | 
           | [Longer ("chronic") fasting was detrimental (in rats, further
           | removed from humans; (and not examined in that paper, just
           | referenced))]
           | 
           | [This is why I like HN, replies backed up with literature
           | references to further meaningful interpretation and
           | discussion #ThumbsUp!)
           | 
           | EDIT: TIL: a _"water fast"_ is not fasting on water but on
           | food... with ample water.... should be called a "water feast"
        
       | josu wrote:
       | It's cool to back it up with data, but any parent who has looked
       | after a newborn knows this.
        
       | precompute wrote:
       | The key to beating this is being self-aware and figuring out when
       | your brain's maintenance cycles are bleeding into your waking
       | thoughts. And use something to cover your eyes while sleeping,
       | even if it's dark outside.
        
       | eggdaft wrote:
       | Hi Hacker News I'm Captain Obvious and I'm here to tell you (and
       | myself) an uncomfortable truth that most of us kinda know but
       | really can't face up to.
       | 
       | Many of us have sleep problems.
       | 
       | We don't have the healthiest lifestyles. Lots of screen use,
       | being very sedentary, many of us eating bad food (it's quick! I
       | can get back to thjngs). Denis Nedry is not a
       | mischaracterisation.
       | 
       | It's not true for absolutely everyone but for the vast majority
       | of people the answer is super simple. You need to exercise. Not
       | even a ton. Three times a week will probably do it. Some cardio
       | some weights, each visit to the gym a decent workout.
       | 
       | This will cost you PS40-PS90 a month. That's about the cost of
       | various Adobe Creative Cloud packages, which enable you to make
       | mediocre graphics on your home personal computer.
       | 
       | for the same price as those photo tweaks you can get: improved
       | longevity, improved all round health, protection against RSI and
       | back problems, hugely reduced stress levels, improved levels of
       | focus and happiness and better relationships. Hey, keep it up for
       | a bit and you'll even get a bit buff and your partner might like
       | that.
       | 
       | We all know this and yet we all seek alternative explanations and
       | remedies: eye masks, Vit D, meditation, dietary fads... because
       | they're so much easier than 2 hour trips to the gym a few times a
       | week. Sure for some people those things are real but for the rest
       | of us it's just procrastination because:
       | 
       | The gym isn't very fun.
       | 
       | Get over it. Put a podcast on, start small, accept that Tuesday
       | night and Thursday night are going to be mostly lost to the gym
       | and just enjoy the journey there and enjoy the music or podcast
       | accompaniment. It's a tax on living. Pay now or pay much more
       | later, your choice.
       | 
       | I struggle with this so hard, but I'm trying ringo, I'm trying,
       | and you should too.
        
       | manmal wrote:
       | Funnily I saw this just yesterday: ,,Dihydromyricetin ameliorates
       | memory impairment induced by acute sleep deprivation"
       | https://pubmed.ncbi.nlm.nih.gov/30876981/
       | 
       | Nootropics Depot now retails this (not affiliated).
        
       | consf wrote:
       | Now reading Why We Sleep: The New Science of Sleep and Dreams by
       | Matthew Walker. Recommend
        
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