[HN Gopher] Intermittent fasting+protein pacing can lead to weig...
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       Intermittent fasting+protein pacing can lead to weight loss, gut
       health
        
       Author : instagib
       Score  : 29 points
       Date   : 2024-06-07 16:45 UTC (6 hours ago)
        
 (HTM) web link (nypost.com)
 (TXT) w3m dump (nypost.com)
        
       | instagib wrote:
       | Nature study pdf link also from the article:
       | https://www.nature.com/articles/s41467-024-48355-5.epdf
        
       | miesman wrote:
       | Summary of the diet used in the study via ChatGPT4:
       | 
       | IF-P Diet Instructions:
       | 
       | Protein Pacing Days:
       | 
       | * Women: 4 meals/day; Men: 5 meals/day.
       | 
       | * Meals: 2 shakes (breakfast + one), 1 whole food dinner, 1
       | afternoon snack (men only), 1 evening protein snack.
       | 
       | * Calories: Women: 1350-1500/day; Men: 1700-1850/day.
       | 
       | * Macros: 35% carbs, 30% fat, 35% protein.
       | 
       | * Fiber: 20-30 g/day.
       | 
       | Intermittent Fasting Days:
       | 
       | * Calories: 350-550/day.
       | 
       | * Fasting Duration: 36-60 hours with supplements and snacks.
       | 
       | Protein Intake:
       | 
       | * Each Shake: 30-36 g protein, 9 g fiber.
       | 
       | * Evening Snack: 200-250 kcals.
        
         | grecy wrote:
         | Even shorter summary:
         | 
         | Eating less energy than the body burns results in burning of
         | stored energy reserves.
        
           | JumpCrisscross wrote:
           | > _Eating less energy than the body burns results in burning
           | of stored energy reserves_
           | 
           | Nope [1].
           | 
           | Even proponents of the energy-balance model clarify that "the
           | brain is the primary organ responsible for body weight
           | regulation operating mainly below our conscious awareness via
           | complex endocrine, metabolic, and nervous system signals to
           | control food intake in response to the body's dynamic energy
           | needs as well as environmental influences" [2].
           | 
           | Calorie in calorie out is the flat-earth model of metabolism,
           | trading truth for simplicity.
           | 
           | [1] https://www.health.harvard.edu/staying-healthy/stop-
           | counting...
           | 
           | [2] https://www.sciencedirect.com/science/article/pii/S000291
           | 652...
        
             | 0cf8612b2e1e wrote:
             | Yet, you can lose weight on Mountain Dew and Doritos by
             | counting calories.                 Little Debbie Snacks,
             | Oreos, Doritos and Diet Mountain Dew sure don't sound like
             | diet food. But a nutrition professor at Kansas State
             | University ate only convenience store snacks for two months
             | and lost 27 pounds.            The key? Moderation.
             | Mark Haub kept his food intake below 1,800 calories a day
             | -- no extra exercise required.
             | 
             | https://www.npr.org/2010/11/12/131286626/professor-s-
             | weight-...
        
               | miesman wrote:
               | Dirty Keto!
        
             | Zanfa wrote:
             | > Each group was given meals with the same number of
             | calories and instructed to eat as much as they wanted, but
             | when participants ate the processed foods, they ate 500
             | calories more each day on average. The same people's
             | calorie intake decreased when they ate the unprocessed
             | foods.
             | 
             | Your own Harvard link supports the calories in/out theory,
             | but argues against counting calories. Different things.
        
               | JumpCrisscross wrote:
               | > _own Harvard link supports the calories in /out theory_
               | 
               | Calorie in / calorie out isn't a theory, it's a
               | thermodynamic corollary. I compare it to flat eartherism
               | because "things go down" is similarly a corollary of
               | gravity. The missed link with the latter is that down
               | isn't what it intuitively means. The missed link with
               | colloquial energy-balance interpretations is "calorie in"
               | and "calorie out" don't mean what people think it does.
               | 
               | If you have a healthy metabolism, cutting calories and
               | increasing burn-- _cereris paribus_ --should spike a
               | starvation response. That has some perks. But it should
               | also reduce your resting metabolism, sometimes below even
               | maintenance levels; it should increase your absorption
               | and sequestration of energy; it should alter your taste
               | to make calories more appetising, and increase
               | existential anxiety around the procuring of those.
               | (Counterfactial: I'm someone who is fine being hungry. )
               | 
               | Just as one can design short bridges on a flat-earth
               | model and be fine, one can deploy this simplistic model
               | (it's not a theory, that's the vastly more complex
               | energy-balance model) to make short-term gains. But it's
               | fundamentally wrong in that it builds the wrong
               | intuitions. Similar to how thinking of our brains as a
               | steam engine or microcomputer sort of works, in some
               | cases, or if you're trying to be punchy in internet
               | comments, but is fundamentally wrong and misleading.
        
         | instagib wrote:
         | From the referenced study supplemental documentation on the
         | "fasting" days and non-fasting days. Even the fasting days they
         | allow you to eat 350-550 calories as aforementioned
         | supplements/snacks for a ~9% weight loss and 17% reduction in
         | desire to eat over 8 weeks. Not bad at all if you can manage to
         | do it: 205lbs->184.
         | 
         | Table
         | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107279/bin/OB...
         | 
         | Doc
         | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107279/bin/OB...
         | 
         | #15 study
         | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107279/#oby23...
        
       | paipa wrote:
       | Title is misleading, the intermittent fasting this paper is
       | talking about is a brutal 350-550 calories per day restriction.
       | That's just fasting.
        
       | penjelly wrote:
       | I'm actually more interested in side effects of prolonged IF or
       | fasting in general. My impression over the long term is it can
       | contribute to gastritis. I don't see any evidence to support this
       | other than anecdotally how it feels to me.
        
       | MrGuts wrote:
       | NY Post: "Mysterious alien eggs spotted in Oklahoma lake"
       | 
       | NY Post: "Trump tells Dr. Phil evil forces are controlling Biden"
       | 
       | NY Post: "How intermittent fasting, protein pacing can lead to
       | weight loss"
       | 
       | What could go wrong?
        
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       (page generated 2024-06-07 23:02 UTC)