[HN Gopher] A primer on the next generation of antibodies
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A primer on the next generation of antibodies
Author : abhishaike
Score : 16 points
Date : 2024-06-05 17:31 UTC (5 hours ago)
(HTM) web link (www.abhishaike.com)
(TXT) w3m dump (www.abhishaike.com)
| frankus wrote:
| I'm curious what the challenges are around using mRNA to
| synthesize antibodies in a person's own cells. A little googling
| turned up this company: https://acuitastx.com/technology/mrna-
| therapeutics/ but I'm curious if there are any obvious
| showstoppers for that kind of thing.
| typingonmyphone wrote:
| I assume the main issue is that antibodies are produced by B
| cells and probably wouldn't be functional if produced by the
| muscle cells that are the traditional mRNA target. And it would
| be transient, your immune system wouldn't learn to make that
| antibody (maybe a feature for a drug).
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