[HN Gopher] Rejuvenating the Blood Cell Population
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       Rejuvenating the Blood Cell Population
        
       Author : etiam
       Score  : 17 points
       Date   : 2024-04-04 19:06 UTC (3 hours ago)
        
 (HTM) web link (www.science.org)
 (TXT) w3m dump (www.science.org)
        
       | robwwilliams wrote:
       | Original paper just published in Nature. This commentary helpful.
       | But not sure I understand this statement:
       | 
       | "...the rebalancing towards the innate immune system with aging
       | is very likely an evolutionary adaptation to keep up acute
       | responses with age while relying more on B-cell memory for the
       | adaptive immune system to handle variations of the usual
       | pathogens."
       | 
       | Selective pressure does not operate after the reproductive phase
       | of life. There is little or no "evolutionary adaptation" to cope
       | with degradation of function with aging.
       | 
       | (The so-called grandmother effect is still a weak hypothesis.)
        
         | throw310822 wrote:
         | > Selective pressure does not operate after the reproductive
         | phase of life.... The so-called grandmother effect is still a
         | weak hypothesis.
         | 
         | If so, then it's really hard to explain how female humans
         | manage to live 40 years past their reproductive age.
        
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