[HN Gopher] On the trail of the Denisovans
       ___________________________________________________________________
        
       On the trail of the Denisovans
        
       Author : georgecmu
       Score  : 23 points
       Date   : 2024-03-02 15:01 UTC (7 hours ago)
        
 (HTM) web link (www.nytimes.com)
 (TXT) w3m dump (www.nytimes.com)
        
       | goles wrote:
       | https://archive.is/TXTdK
        
       | rhelz wrote:
       | No doubt there are many, many other varieties of humans which
       | we'll never know about because we'll never find any bones.
       | 
       | What chilling is that shows very clearly that humans can go
       | extinct. In fact, humans go extinct all the time: 50,000 years
       | ago, we shared the earth with at least 5 different varieties of
       | humans (Homo Neanterthalensis, Homo Denisova, Homo Naledi, Homo
       | Florensiensis, and Homo Luzenenensis). Probably also some late
       | surviving populations of Homo Erectus and Homo Rudolfensis.
       | Almost certainly more we'll never know about.
       | 
       | Since the last ice age we've been dropping like flies. In fact,
       | we're the only humans left. And what with climate change,
       | accidental nuclear war, or the singularity looming, we are
       | arguably in a more precarious position than we've ever been.
        
         | huytersd wrote:
         | Humans have never had the numbers they've had right now. It
         | would be very hard to eradicate 8 billion individual organisms.
        
           | Simon_ORourke wrote:
           | What do you mean hard? I do this all the time with some
           | bleach and a scrubbing brush.
        
             | huytersd wrote:
             | Global scale bleach events are rare.
        
               | AndrewKemendo wrote:
               | This offered me a good laugh. Thank you.
        
           | account-5 wrote:
           | We're trying our best though.
           | 
           | EDIT: for those downvoting, I'd like to discuss why you don't
           | agree. I mean, climate change, war, etc. What else can you
           | call it?
        
             | echelon wrote:
             | No amount of climate change short of Venusian runaway
             | heating will scour the earth of humans.
             | 
             | If we launch all of our nukes, we might collapse
             | civilization, but even that would likely leave humans
             | around. We might get stuck in our gravity well for a long
             | time, though.
             | 
             | Whatever makes us go extinct will either be cosmic or
             | something we haven't invented yet.
        
               | account-5 wrote:
               | I think the amount of climate change that kills off our
               | food or the atmosphere we breath might do it.
        
               | huytersd wrote:
               | An appropriate virus would do it. Spread through the air,
               | 5 year incubation rate, 90%+ mortality would do it.
        
               | rhelz wrote:
               | // venusian runaway...//
               | 
               | We cool our bodies by sweating, a process which ceases to
               | work at about 95 degrees at 100% humidity, or 115 degrees
               | at 50% humidity. Its been estimated that an average
               | temperature of above 122 degrees F would kill off all
               | mammalian life on the planet.
               | 
               | Currently the earth is warming at about 1/3rd of a degree
               | F per decade.
        
               | echelon wrote:
               | Seeing how the summer mean daily maximum in my city is
               | 95.8 deg F and the mean humidity averages 80%, I think we
               | already cross your threshold frequently. It hasn't killed
               | us yet. I would frequently go running in the afternoon
               | during "heat stroke" days. I love that weather. Hot and
               | humid summers are personally invigorating. I grew up with
               | them. I'd like to see your sources.
               | 
               | > Currently the earth is warming at about 1/3rd of a
               | degree F per decade.
               | 
               | Every decade our technological capability increases
               | dramatically. We're already working on climate
               | engineering. Nothing here will extinct us.
        
               | rhelz wrote:
               | // I'd like to see your sources //
               | 
               | See the July 19, 2022 Issue of the Scientific American,
               | "How Hot Is Too Hot for the Human Body?"
               | 
               | // I would frequently go running //
               | 
               | Recall, it's 95 degrees at 100% humidity. The more humid
               | the air, the less sweat will evaporate. I don't care if
               | you are Jesus Christ Usane Bolt Superstar, above 95
               | degrees at 100% humidity, if you run long enough you will
               | get heatstroke.
               | 
               | // Nothing here will extinct us // Extinction has
               | happened to every other species of Homo. Every. single.
               | one. I wonder how many of them accurately predicted when
               | and why they would go extinct....
        
               | echelon wrote:
               | I spent fifteen minutes in a 112 deg F shower today [1]
               | at presumably near total humidity. I do this all the
               | time, and that isn't even hot.
               | 
               | I was born and live in heat, so when I hear cold climate
               | SF denizens say the end is nigh, I have to chuckle.
               | 
               | I took a look at your source [2]. I'll have to read the
               | underlying literature. The way this is presented to a lay
               | audience doesn't make it clear if they're controlling for
               | acclimation. I'm not educated in physiology beyond an
               | undergrad class, so I'm not sure if their measure is a
               | good proxy.
               | 
               | It'll take sixty years to raise the temperature two
               | degrees, after which I'll probably be dead. It'll take
               | centuries to push into dangerous ranges. I think we're
               | already building the tech to deal with this, and very
               | little growth is exponential. This is going to be yet
               | another sigmoid. And in geologic times, just noise.
               | 
               | I will say I am worried about loss of species diversity.
               | But I'm more worried about a lack of cheap energy to fuel
               | our ascendent climb to the next stages. And more worried
               | about nukes.
               | 
               | As far as green tech goes, I've always been worried about
               | particulate matter in the air leading to cardiopulmonary
               | diseases. So it's not a bad thing and I've never once
               | been against it.
               | 
               | What I am concerned about is that we're teaching Gen Z
               | and Gen Alpha to just give up. Go look at /r/GenZ and all
               | the threads about climate - these kids are just giving up
               | on life because of these memes. In reality, their lives
               | will not be impacted by climate change whatsoever. We're
               | scaring them to death and their entire generation is
               | experiencing trauma because of this.
               | 
               | We do need to control these systems, and we do need to
               | protect ecosystem biodiversity, but this hysteria is
               | ridiculous.
               | 
               | [1] I just measured the water temperature.
               | 
               | [2] https://www.scientificamerican.com/article/how-hot-
               | is-too-ho...
        
               | rhelz wrote:
               | // I spent fifteen minutes in a 112 deg F shower...I
               | spent fifteen minutes in a 112 deg F shower //
               | 
               | Did you measure your body temperature? Were you able to
               | cool yourself by sweating, or was your body temperature
               | monotonically rising?
               | 
               | Recall, it is recommended that you go to a doctor if you
               | have a fever of over 103 degrees, and over 108 degrees
               | you risk brain damage.
               | 
               | Soaking some nice heat into your sore muscles in a
               | 20-minute shower is one thing; but 24/7 your body is
               | absolutely, positively not able to cool itself down is
               | quite another.
               | 
               | // They don't control for so many things, let alone
               | acclimation. //
               | 
               | Hey man, I gave you a source as requested. Whether or not
               | evaporating water can cool down a body of a certain
               | volume and surface when that body is internally
               | generating heat--that isn't a matter of acclimation, its
               | a matter of thermodynamics.
               | 
               | // after which I'll probably be dead // And why think
               | about extinction after I'm dead, eh? :-) But far before
               | 60 years passes, you'll find yourself in the age
               | demographic for which death from hot weather is a risk.
               | The body's ability to thermoregulate degrades as we get
               | older, alas...
               | 
               | // worried about a lack of cheap energy // Wind farms are
               | already cheaper to build than coal-fired plants. And if
               | you factor in all the externalities, fossils fuels don't
               | even come close to being a cheap source of energy.
               | 
               | // we're teaching Gen Z and Gen Alpha to just give up...
               | this hysteria is ridiculous // Worrying about how the
               | media affects "kids these days" is a normal, expected
               | part of the aging process :-) ....maybe, perhaps, the
               | thought that Gen-Z and Gen-X are just giving up is a bit,
               | well, I won't say hysterical, but perhaps a bit
               | hyperbolic? And inasmuch as they are going to be here
               | longer than we are, they do have a bit more of a stake in
               | the future than we do.
        
             | cgh wrote:
             | War? We live in one of the most peaceful times in human
             | history.
        
         | polishdude20 wrote:
         | Wonder if there's a structure of ours that's akin to the
         | pyramids. But like, something that would last millennia.
        
           | blamazon wrote:
           | Hoover dam? Svalbard seed vault?
        
           | klyrs wrote:
           | Open pit mines seem to be a pretty good candidates for this.
           | They're pretty much the opposite of a structure, but I can't
           | imagine them looking "natural" even thousands of years from
           | now. I can imagine one or two getting overgrown, but ones in
           | desert areas like Utah could last until the next deep ice
           | age.
        
             | polishdude20 wrote:
             | Yeah I guess you can look at ancient craters from meteors
             | or volcanos to see how it would look.
        
               | klyrs wrote:
               | Can we? I'm not under the impression that those were ever
               | terraced[1] like open-pit mines. But come to think of it,
               | terracing itself qualifies as a megastructure[2]. Where
               | the Long Now clock is an offbeat art project, rice
               | paddies are crucial for nutrition for a great many people
               | and they've already been around for at least 2 millenia.
               | As times get lean, I can imagine pilfering the Long Now
               | clock for parts; but those rice paddies will only gain
               | importance.
               | 
               | [1] https://www.dreamstime.com/stock-photography-bingham-
               | kenneco...
               | 
               | [2] https://en.wikipedia.org/wiki/Rice_Terraces_of_the_Ph
               | ilippin...
        
           | AlbertCory wrote:
           | There's a good book, _The World Without Us_ that goes into
           | great detail on what would happen if humans disappeared.
        
         | fredsmith219 wrote:
         | The other species are gone because we eliminated or out
         | competed them. Even with climate change we're in no danger of
         | extinction
        
           | slashdev wrote:
           | This. It would take something truly catastrophic to make
           | humans extinct now that there are so many of us on every part
           | of the globe.
           | 
           | Climate change won't cut it, neither would total nuclear war.
           | 
           | Even if you had something like an impact big enough to
           | superheat the entire atmosphere, enough humans might survive
           | inside buildings, basements, subways, etc to carry on.
           | 
           | Modern civilization though is a lot more fragile. It's
           | possible to blast us back to pre-industrial times and the
           | easy to access resources are mostly gone. It's not clear that
           | we could bootstrap a second industrial revolution easily.
        
             | Cacti wrote:
             | eh. you underestimate global thermonuclear war.
        
               | philipkglass wrote:
               | Global thermonuclear war would destroy technological
               | civilization, but even now there are small groups of
               | pastoralists and hunter-gatherers in remote regions who
               | use only muscle power and do not need factory
               | manufactured goods. Uncontacted tribes [1] would go on
               | living much as usual if a nuclear war depopulated
               | industrialized regions.
               | 
               | There would be some increase in mortality among remote
               | tribes as radioactive fallout from a large scale nuclear
               | war drifted down globally, but that wouldn't be enough to
               | cause human extinction.
               | 
               | [1] https://en.wikipedia.org/wiki/Uncontacted_peoples
        
             | bryanlarsen wrote:
             | OTOH our garbage and wreckage will provide a lot of
             | resources. For example there may not be any easily
             | accessible copper deposits, but there are a lot of wires to
             | scavenge. No easily accessible fossil fuels, but the amount
             | of plastic in garbage dumps makes them a fossil fuel
             | source.
        
             | nicklecompte wrote:
             | To be clear I don't think anthropogenic climate change will
             | cause human extinction. But a terrible series of volcanos
             | could absolutely turn Earth into a colder Venus for, say, a
             | couple hundred years - pelagic vertebrates and certain
             | microbes would be ok, but I am not sure humanity would
             | survive more than a few generations, even in underground
             | sci-fi bunkers.
             | 
             | https://en.wikipedia.org/wiki/Permian-
             | Triassic_extinction_ev...
        
               | slashdev wrote:
               | It would have to be worse than the previous volcanic
               | extinction events, which were massive. It's not clear the
               | Earth can even do that anymore.
        
               | nicklecompte wrote:
               | > It's not clear the Earth can even do that anymore.
               | 
               | This is a good point, but the event wouldn't need to be
               | more volcanic so much as that volcanism would need to
               | ignite more carbon-containing materials - naively I would
               | expect there to me more "fuel" in the Earth than there
               | was 300m years ago.
        
           | Anotheroneagain wrote:
           | We are at an imminent threat of extinction.
        
             | Cacti wrote:
             | We are? You have evidence for this?
        
               | Anotheroneagain wrote:
               | Yes. The near future will decide if and to what extent
               | the life on Earth will survive because of what those
               | madmen did.
        
           | mistrial9 wrote:
           | here are some non-human species "we eliminated" in Latin
           | naming system
           | 
           | https://en.wikipedia.org/wiki/IUCN_Red_List_of_extinct_speci.
           | ..
        
           | arp242 wrote:
           | Also the population for many of these earlier humans was much
           | much lower. It's hard to give accurate population counts for
           | many of these earlier humans - we don't know all that much
           | about Denisovans - but for Neanderthals the total population
           | was in the tens of thousands.
        
         | shrimp_emoji wrote:
         | https://en.wikipedia.org/wiki/Competitive_exclusion_principl...
        
         | hunglee2 wrote:
         | it's possible to have a more positive take on this - those
         | species did not go entirely extinct, as their genes continue
         | live on within many of us - and thus we carry their legacy as
         | much as we do for homo sapien. We might even speciate again one
         | day, should genetic populations isolate again for a time
        
           | lordnacho wrote:
           | That's what I understood as well. In a way, they live on with
           | us because they are part of the same species. We know that we
           | have bred with Neanderthals. Why aren't they just considered
           | a branch of humanity? It's normal for some designs to die out
           | in favour of others. Slightly stocky humans with bigger
           | brains. If you met one, I wonder what you'd think in
           | comparison with, say, a person from another culture?
        
         | softg wrote:
         | >Since the last ice age we've been dropping like flies. In
         | fact, we're the only humans left.
         | 
         | I was under the impression that was our doing. All of these
         | human varieties were outcompeted by homo sapiens who replaced
         | them. Modern humans don't need to worry about another hominid
         | taking their place because we're the last one standing.
        
           | shakezula wrote:
           | We're so good at it we're going to outcompete ourselves in
           | fact
        
           | rhelz wrote:
           | It's one possible theory, and no doubt, at the very least, it
           | was part of the reason they died. But that's not the only
           | smoking gun.
           | 
           | E.g. For at least 200k years, we can tell by fossils from the
           | middle east that we made many attempts to spread to Europe,
           | but were always pushed back. Fun fact: Neanderthals actually
           | had substantially bigger brains that we do today (their
           | average size was about 1400-1500ccs. Subtract the volume of a
           | tennis ball from that and you'll get the average size of our
           | brains today). Neanderthals were smart, tough, mofos.
           | 
           | So what changed 50k years ago which finally let us succeed?
           | Well, the climate was warming from the last ice age, and
           | Neanderthals were very much cold-adapted hominids. Their
           | short, stocky legs and heavy muscular arms were great at
           | sneaking through the woods and stabbing a deer with a spear,
           | but when the climate changed the woods disappeared, those
           | short legs, hauling a very heavy upper-body musculature, were
           | not so good at running the deer down on a plain.
           | 
           | Honestly, we have no real definitive answer to why we are
           | here and they aren't. Like anything else, probably it was a
           | complicated process in which lots of factors--including dumb
           | luck--played a role.
           | 
           | For about 4 million years, the earth was very hospitable to
           | all kinds of species of Homo--we find their bones, in a
           | kaleidoscope of shapes and sizes, all over the old world.
           | Since the last ice age, however, Homo has been having a
           | really rough time of it. And we are the only humans left.
           | 
           | If you were locked in a room with 10 people, and one by one
           | they started to disappear, when you were the only one left,
           | you might wonder whether it would happen to you too.....
        
             | allendoerfer wrote:
             | The fact, that I am sitting here slacking off, reading
             | something some dude wrote on the other side of the world
             | just because he had nothing better to do and wanted to
             | enjoy and share his own thoughts, takes away the fear of
             | imminent extinction of my species.
        
             | temp0826 wrote:
             | Fun to think about. Maybe they were bigger and stronger,
             | which forced us to actually be more clever and start to use
             | our smaller but still very capable brains to accomplish
             | stuff. I don't know if there were actually interactions
             | between the different species, but I sure wouldn't want to
             | fight a neanderthal without a plan or some tools.
        
       | verisimi wrote:
       | > In a new review paper, anthropologists tally all of the fossils
       | that have been clearly identified as Denisovan since the first
       | discovery in 2010. The entire list consists of half a broken jaw,
       | a finger bone, a skull fragment, three loose teeth and four other
       | chips of bone.
       | 
       | Right... is that enough? Then:
       | 
       | > "What we have found out about Denisovans is that, from a
       | behavioral perspective, they were much more like modern humans,"
       | said Laura Shackelford, a paleoanthropologist at the University
       | of Illinois.
       | 
       | How can anyone make those sorts of leaps, on the basis of a tooth
       | and some bone chips?
       | 
       | > Dr. Shackelford said findings like these raised the possibility
       | that Denisovans and modern humans coexisted and interacted for
       | tens of thousands of years -- though whether they communicated is
       | unclear. "That's really going down the rabbit hole," Dr.
       | Shackelford said.
       | 
       | What he's saying is we can't tell if these purported species
       | communicated, on the basis of what seems to me to be super
       | lightweight evidence. He said "communicate"!
        
         | WalterBright wrote:
         | How does one tell a skull fragment is a different species?
        
           | verisimi wrote:
           | Via DNA, it says. But I can't get to the bottom of why DNA
           | analysis is considered to be solid, when there are examples
           | of it being quite flawed, eg with these twin sisters:
           | 
           | https://www.youtube.com/watch?v=Isa5c1p6aC0
           | 
           | Someone said that these consumer outfits are known to be
           | trash - but I presumed that all DNA tests would end up going
           | to the same labs, and those labs would use the same
           | principles to test.
           | 
           | There is quite a big question for me about the validity of
           | DNA as evidence, when it is possible to show how some tests
           | fail.
        
             | Tagbert wrote:
             | Automatic genetic testing in a commercial lab is not the
             | same thing as controlled analysis by anthropologists and
             | geneticists.
        
               | verisimi wrote:
               | Are you arguing that adding an anthropological
               | interpretation over the top of the automatic testing adds
               | value? Or that it is a fudge to make the automatic
               | testing fit whatever criteria are required?
        
               | jvanderbot wrote:
               | I think the argument was that mass produced testing is of
               | lower quality than top scientific labs dedicating all
               | their expertise on a specific sample or two.
        
               | shakow wrote:
               | They are not the same process at all. Commercial
               | ``automated'' kits only genotype you, i.e. look at a
               | couple thousands of well known SNPs to put you in the
               | group you share more with. Resolution is low,
               | extrapolation is virtually impossible, but it's cheap and
               | fast, and Uncle Joe can claim his 15% Italian ancestry.
               | 
               | Work like those done on these denisovan is a whole other
               | can of worms, which is still a very vibrant field
               | (https://en.wikipedia.org/wiki/Ancient_DNA) - at least it
               | was when I left it a couple years ago. The main
               | difference being that it's trying to sequence as much of
               | the genome as possible, using the better preserved DNA
               | molecules, typically in the teeth or some places in the
               | skull. Then it's dozen of hours of menial work by
               | specialized worker using protocols light-years ahead of
               | what is done for the commercial kits.
               | 
               | To make a good ol' HN car comparison, it would be like
               | saying that because some chain carshop once screwed your
               | head gasket change, there is no way anyone could ever
               | restore a Cobra.
        
             | kjkjadksj wrote:
             | Those kits are genotyping you. For these ancient dna
             | analysis they are performing whole genome sequencing which
             | is a different technology.
        
           | Tagbert wrote:
           | Morphology and genetics
        
         | baerrie wrote:
         | https://youtu.be/g4F6BlD8mZs?si=iszAW6tgxH3oUWy1
         | 
         | This nobel winner's lecture on the topic goes into the genetic
         | details and covers how they make the more general conclusions
        
       | kgeist wrote:
       | The article says:
       | 
       | >In Tibet, Dr. Huerta-Sanchez and her colleagues have found a
       | Denisovan gene that helps people survive at high altitudes
       | 
       | Can't it be simply convergent evolution?
        
         | rhelz wrote:
         | Anything is possible, but it would kind of be like finding two
         | pc-clones, both which contained a copy of MS-DOS, and
         | concluding that each was independently programmed.
         | 
         | For the kinds of arguments which scientists use to support
         | these claims, see "Altitude adaptation in Tibetans caused by
         | introgression of Denisovan-like DNA" by Emilia Huerta-Sanchez,
         | et al.
        
         | kryptiskt wrote:
         | It would be weird to have the same DNA sequence from convergent
         | evolution, since even if evolution converged on exactly the
         | same protein (unlikely as that may be), most amino acids in the
         | sequence can be represented by several different DNA triplets
         | and there is absolutely no reason why it should converge on the
         | same triplets.
        
       | profsummergig wrote:
       | Because Neanderthals were discovered in Europe, people think
       | Neanderthal DNA is a marker of European ancestry.
       | 
       | East and South Asians, and Native Americans have higher
       | Neanderthal DNA than Europeans.
       | 
       | Source: https://images.app.goo.gl/Q1JLpT6MqiubCHq18
        
       | MilStdJunkie wrote:
       | There's a non-zero chance that many of the asiatic H. Erectus[0]
       | found during the late 19th and early 20th century are, in fact,
       | Denisovans or their relatives, but were recovered in a period
       | where our ideas about human migration were quite different from
       | today's . . and _long_ before genetic analysis[1]. When the
       | remains are examined in their entirety, the variations are quite
       | extreme, with brain sizes ranging from near-ape to practically
       | modern.
       | 
       | [0] i.e., Java Man [1] Revealing peoples like the Andaman
       | islanders as having a high proportion of non-Sapiens non-
       | neanderthal DNA, something that would fit into a 19th century
       | anthropology not at all.
        
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