[HN Gopher] Some fish live beyond 100 and get healthier as they age
       ___________________________________________________________________
        
       Some fish live beyond 100 and get healthier as they age
        
       Author : prmph
       Score  : 159 points
       Date   : 2024-01-21 13:01 UTC (9 hours ago)
        
 (HTM) web link (www.nationalgeographic.com)
 (TXT) w3m dump (www.nationalgeographic.com)
        
       | callamdelaney wrote:
       | Paywall
        
       | idopmstuff wrote:
       | https://archive.is/WTVrj
        
       | Jeff_Brown wrote:
       | tl;dr:
       | 
       | The older ones are better able to fight bacteria, and have a
       | "lower ratio of neutrophils to lymphocytes in the blood", which
       | ratio indicates stress. They evolved to live a long time because
       | good breeding conditions are rare. No word on biochemical
       | mechanisms.
        
       | j16sdiz wrote:
       | > These calcium carbonate structures, which allow fish to hear
       | and sense vibrations in the water, form a new layer each year
       | that can be read somewhat like tree rings.
       | 
       | Each time I read dating method like these, I wonder how stable
       | these method are. Sure they are sensitive to water temperature,
       | right? We have not-so-long-term climate changes, periodic solar
       | storms and irregular volcano eruption.. All these are affect
       | water temperture...
        
         | taway_6PplYu5 wrote:
         | Wait, so you are saying that over the course of 85 years, we've
         | had enough volcanic eruptions to disrupt the counting of the
         | equivalent of tree rings in fish bones, in a lake in Arizona?
         | When we KNOW when the fish were first put there?
         | 
         | Has Arizona had that many volcanic eruptions in the 20th
         | century which we somehow forgot to notice, but were still
         | strong enough to disrupt the fish?
         | 
         | https://tucson.com/news/local/environment/old-fish-in-arizon...
         | 
         | Just over a century ago, several hundred game fish raised in
         | ponds in Iowa were hauled across the country by rail to be
         | released into Arizona's newly dammed Salt River.
         | 
         | A recent study suggests some of those transplanted buffalofish
         | are still alive today in the waters of Apache Lake.
         | 
         | Not their descendants. Not members of the same species. The
         | same individual fish that were sent west in 1918, as World War
         | I was winding down in Europe during Woodrow Wilson's second
         | term as president.
        
         | MostlyStable wrote:
         | Yes, they are susceptible to temperature. Seasonal temperature
         | changes are mostly what causes them in the first place.
         | Additionally, researchers have used water temperature to create
         | otolith barcodes in captive fish before release. Otolith bands
         | are the result of seasonal changes in growth rate, which is
         | highly trusted to temperature and is why it's a less reliable
         | technique in tropical or deep water species.
         | 
         | That getting said, climate change and other things are unlikely
         | to overwhelm the seasonal cycles. Yes, it's gotten warmer, but
         | it's still colder in winter.
         | 
         | It's also preferable to have validation for a given taxa, but i
         | wouldn't expect that particular worry to be the failure more.
        
       | adrianvoica wrote:
       | That's because they drink a lot of water, and everybody knows
       | water is good for you. :)))
        
         | 6d6b73 wrote:
         | Or maybe that physican of the Chinese emperor was right that
         | mercury is the key to immortality?
        
           | bbarnett wrote:
           | Wait, is it? The FDA lied about masks, and bleach, and now
           | mercury?
           | 
           | Do you know where I can get some?
        
             | taway_6PplYu5 wrote:
             | The trick is you need to filter it through asbestos before
             | you drink it.
        
               | InSteady wrote:
               | Kindly consider taking these mediocre jokes back to
               | reddit, all of you.
        
         | MarkusQ wrote:
         | Nah, it's the fish oil that does it.
        
       | bestouff wrote:
       | > In one study, bigmouth buffalo had stronger immune systems than
       | younger fish.
       | 
       | Or maybe only fishes with a stronger immune system get older ?
        
         | crazydoggers wrote:
         | Selection bias ~= natural selection.
         | 
         | If bigmouth buffalo procreate for more years because they live
         | longer with stronger immune systems, then they will eventually
         | make up the majority of the population.
        
           | np_tedious wrote:
           | So long as they remain capable of reproduction in those later
           | years
        
             | baxtr wrote:
             | Is that so? I thought it's enough if they provide an
             | advantage for their genes.
             | 
             | Maybe healthier older fish protect their offspring more
             | effectively.
        
               | crazydoggers wrote:
               | Yes, you're 100% correct. You've described kin selection.
               | So if grandparent fish can somehow help their
               | grandchildren procreate more, then that can be selected
               | for.
               | 
               | I've heard of territory defense helping with fish, but no
               | idea about the fish mentioned specifically.
               | 
               | Also to the previous comment, I think there's already a
               | fair bit of evidence that older larger fish do continue
               | to breed, (hence throwing back the bigger fish breeders).
               | 
               | But if they stop breeding, and there is no kin selection;
               | then yes, natural selection wouldn't play a role.
        
             | DelaneyM wrote:
             | Or if they care for their descendants in their later years.
             | 
             | (Not saying fish do this, though I wouldn't be surprised if
             | giant elder fish clear out predators. A lot of people
             | forget this bit but it's suspected of being a big factor in
             | insect and lobster longevity, which both capable of
             | recognizing their offspring and not being territorial to
             | their presence.)
        
         | makz wrote:
         | You may be into something. I've been on the fish keeping hobby
         | for decades and right now the number 1 cause of mortality of
         | captive fish is immune system overload.
        
         | pitdicker wrote:
         | Or something changed in the environment that made younger fish
         | less healthy.
        
         | kristopolous wrote:
         | Do you really think the researchers aren't aware of
         | survivorship bias?
        
       | pingou wrote:
       | "The otolith analysis revealed that about 90 percent of Apache
       | Lake's buffalofishes were more than 85 years old". That sounds
       | very fishy. Perhaps they just have some sort of genetic code that
       | make them create those new layers of calcium carbonate structures
       | more often than once a year.
        
         | inciampati wrote:
         | This is not "genetic code"!
        
         | MostlyStable wrote:
         | It is important to validate any aging method, including
         | otoliths, and there have been cases of system misaging. The fin
         | ray and scale based ages used in West Coast ground fishery
         | management in the 80s resulted in systemic under aging that
         | contributed to the over fishing and collapse of multiple
         | rockfish species, for example. But otoliths in temperate fish
         | species are generally one of the most consistent and reliable
         | aging methods across multiple taxa.
         | 
         | So hopefully otolith aging has been validated for this species
         | in particular or at least a closely related one, but if not
         | it's more likely than not reasonably reliable.
         | 
         | As for the population dynamics, it's not actually necessarily
         | that strange. For many species, mortality occurs almost
         | entirely in the early life history. Once fish escape that
         | period, they are very unlikely to die. This can take in exactly
         | this kind of dynamic were very few young fish are alive at any
         | one point and most of the extent fish are very old.
        
           | pvaldes wrote:
           | > otoliths in temperate fish species are generally one of the
           | most consistent and reliable aging methods
           | 
           | Ha ha ha haaaa!!
           | 
           | Sorry, but that claim was hilarious. I had the (lets call it)
           | "pleasure" to read otoliths in the past, and consistent and
           | reliable is not how I would describe it. Not even close. For
           | most species it just happens that nobody validated the system
           | first. This means that everybody extrapolates, but nobody
           | really knows how many rings are formed each year. But "oh,
           | that fish lived for 800 years"... highly publishable
        
             | MostlyStable wrote:
             | I currently work in a lab that primarily does otolith based
             | growth and aging. It is and has been my primary job for
             | over 7 years (although I don't do that actual reading of
             | the otoliths, I work with the data that comes out of it)
             | 
             | I think you are misreading my comment. I did not say that
             | it was easy or that it was always consistent and reliable.
             | I said it was one of the most consistent and reliable aging
             | methods, which is an inherently relative statement.
             | Compared to other common aging techniques such as scales,
             | fin rays, and vertebrae, it is exactly those two things:
             | _more_ consistent and reliable.
             | 
             | It can be _more_ and yet still not _particularly_. And, in
             | many cases, yes, it is not always very reliable and in many
             | species it has not been specifically validated. But it is
             | still the best, more reliable technique we have for aging
             | fishes. In addition, please note that _literally_ the first
             | sentence in my comment was the importance of validating an
             | age technique. I am well aware of the issues in aging.
             | Those issues absolutely do not amount to the (implied)
             | conclusion of your comment that they are garbage that
             | shouldn 't be relied upon.
             | 
             | Also, just a piece of advice: you do not come off as
             | particularly authoritative when you make wildly hyperbolic
             | statements like contesting claims of 800 year old fish.
        
         | nilsherzig wrote:
         | Fishy
        
       | fb03 wrote:
       | That is beyond amazing to me.
       | 
       | As a layperson in biology related stuff, I'd like to ask: How do
       | scientists estimate the age of non-human animals?
        
         | rpmisms wrote:
         | For some fish, you can count the rings on their scales like a
         | tree.
        
         | momento wrote:
         | Look up Otoliths. It's a bone in the ear of fish that is
         | commonly used for aging.
        
         | MostlyStable wrote:
         | Otoliths are calcium carbonate structures that form in the
         | heads of fishes that help with balance and orientation. Humans
         | actually have similar things in their ear canals, they just
         | don't aggregate and it's more like sand.
         | 
         | These structured grow with the fish and seasonal changes in
         | growth rate cause lighter and darker alternating bands, similar
         | to tree rings. When prepared correctly, these bands can be
         | viewed and counted inter s microscope.
         | 
         | Similar methods are used in fin rays and spines, scales, and
         | vertebrae, although otoliths are generally considered the gold
         | standard
        
       | Symmetry wrote:
       | It's not clear from the article but animals can generally live
       | quite a bit longer than you'd expect if they continue to grow for
       | their entire life, which is true for some types of fish. Gunk
       | that builds up inside or between cells gets redistributed over
       | larger areas, as do cells that become senescent. And larger size
       | means more space for memory T cells. Those are only some aspects
       | of aging of course.
        
         | thfuran wrote:
         | Don't cancer rates tend to correlate positively with number of
         | cells?
        
           | BiteCode_dev wrote:
           | Not for whales so YMMV.
        
             | thfuran wrote:
             | It's not consistent across species because different
             | species have different mechanisms for averting tumor
             | growth. But within species (certainly among humans, and I'm
             | pretty sure also among others), more cells means more
             | opportunities for something to go wrong and so more cancer.
        
               | jb1991 wrote:
               | Counterpoint: elephants.
        
             | feedsmgmt wrote:
             | Isn't that because the ocean water blocks radiation?
        
           | wongarsu wrote:
           | Yes, but the bigger you are the bigger the tumor has to be to
           | notably impact your health.
        
           | jb1991 wrote:
           | No; elephants are a good example of animals with relatively
           | low cancer rates.
        
             | agumonkey wrote:
             | so it's a matter of density (which is probably what
             | grandparent was hinting at)
        
         | DougWebb wrote:
         | So, getting fatter as I get older is a good thing? /s
        
           | bloomingeek wrote:
           | Good morning to you, sir!
        
       | swayvil wrote:
       | It's all the cardio. Fish do cardio 24-7 their whole life.
       | Therefore older=better.
        
         | bbarnett wrote:
         | Most fish (non domesticated) I've seen, tend to find places to
         | hide while sleeping. Rocks, crevasses, in plants.
         | 
         | Are cattle doing cardio because they're standing while
         | sleeping?
         | 
         | I see what you're saying, but fish don't have to do a lot to
         | station keep.
        
           | pvaldes wrote:
           | well said, Catostomus are carps that remain still in the
           | bottom a lot of time. They are not big swimmers. Their main
           | concern is to suck a rock with enough force to stand their
           | ground against currents. Remaining in waters with a lot of
           | oxygen, that just travel straight to your gills, is like a
           | holiday for the heart.
        
         | InSteady wrote:
         | What's with the low effort, mediocre joke posts today?
        
           | swayvil wrote:
           | What takes less effort, the low effort post or the complaint
           | about the low effort post?
           | 
           | But seriously, it's a subtle joke meant for esoteric
           | perspectives. Intended for like 1%.
        
       | sirobg wrote:
       | > Buffalofish can go decades between successful reproductions
       | because they require very specific environmental conditions--most
       | of which are still unknown--to procreate. That's why the fish
       | evolved to live so long: It's an evolutionary adaptation to
       | account for long periods without breeding, according to Lackmann.
       | 
       | This reminds me of "The Fable of the Dragon-Tyrant" by Nick
       | Bostrom [1]. Senescence is engraved in our brains as universal.
       | Just like our expectation about health which should deteriorate
       | overtime.
       | 
       | [1] https://nickbostrom.com/fable/dragon
        
         | 7thaccount wrote:
         | What a wonderful fable. I enjoyed reading it and wish there was
         | more research occuring in this field. Still, I'm impressed from
         | what I hear in the news from time to time.
        
           | sirobg wrote:
           | Yes it's so good.
           | 
           | An amazing way to give a new perspective on life and death as
           | we know it _today_ imho.
           | 
           | Strong emphasis on _today_ because life expectancy, healthy
           | life expectancy and death are already really different from
           | some time ago.
           | 
           | https://en.m.wikipedia.org/wiki/Life_expectancy
        
           | nradov wrote:
           | There is an enormous amount of money being spent on research
           | to figure out how to prevent people from dying. You're
           | welcome to donate your own money to the many non-profit
           | foundations issuing research grants in that field.
        
         | flqn wrote:
         | A well written fable, but its moral would not be equitable in
         | the world of today. It's inevitable that access to "defeating
         | the dragon" would be available to only the most affluent in
         | society, whom have also led the most comfortable lives. There
         | is no fairness in allowing these people to enjoy extended or
         | indefinite lifespans whilst countless others suffer inhumane
         | conditions only to die early.
        
           | narcraft wrote:
           | This is an argument against pursuing equitability as an end
           | in and of itself
        
             | flqn wrote:
             | I disagree, it's more an argument that even though
             | advancement of human capability can bring great gains
             | (defeating the dragon) we need to pursue equitability in
             | these gains or otherwise they are unethically allocated.
             | 
             | The rising tide should raise ALL boats, otherwise
             | inequitability will lead to social instability as seen
             | througout human history so far.
        
               | benlivengood wrote:
               | While I agree that modern societies and especially global
               | wealth are very inequitable I think medicine is one of
               | the areas where it is _almost_ universally agreed in
               | practice to raise all boats. Generic medications are made
               | available, foreign aid is often in the form of medicines
               | and medical support, and global institutions are funded
               | with the aim of raising all boats. Should life extension
               | become possible through medicine or treatments it seems
               | likely that the existing process of trying to achieve
               | global medical equity will continue. Clearly life
               | extension will be very highly valued and if it is out of
               | reach of 95% or 99% of the human population there will be
               | intense pressure to socialize its benefits to everyone.
               | Where I can see problems is if life extension is out of
               | reach of 50% or 75% of the world population due to
               | material /equipment/personnel costs; that's a lot harder
               | to socialize globally and would be similar to advanced
               | cancer treatments and organ transplants/replacements
               | which could be seen as the leading edge of longevity
               | treatments.
               | 
               | I don't think there's a moral argument against expensive
               | cancer/organ treatments being made available in wealthy
               | countries; it doesn't seem like any progress on treating
               | those diseases will be made at all if the treatments
               | can't be made available, regardless of their extreme
               | inequity.
        
           | sirobg wrote:
           | I think medicine gave a good hit to the dragon over the
           | years.
           | 
           | At first only rich people beneficiated from it. But
           | thankfully today medicine advantages are better distributed.
           | We are not equals by any means and some countries are lagging
           | behind, but it is better.
           | 
           | Link to my other comment:
           | https://news.ycombinator.com/item?id=39080399
           | 
           | I have good hopes the same pattern could occur here.
        
             | flqn wrote:
             | Perhaps the "rising tide" takes longer to reach some than
             | others. I hope for a more equitable, fairer future, but
             | it's likely my outlook is somewhat jaded.
        
               | sirobg wrote:
               | Honestly I also get your take. I think it will depend on
               | the "thing" that will enable us to live longer and
               | healthier.
               | 
               | If it is something very expensive and an overnight
               | discovery, then it is likely that a dystopian era will
               | occur... Just imagine some kind of tyrant (as a reference
               | to the fable!) reigning over a country for 100+ years.
               | 
               | But it could also be somewhat like what happened with
               | medicine: the sum of smaller improvements, some more
               | expensive than others, years after years.
        
               | wholinator2 wrote:
               | I agree, the tide analogy kinda breaks down here though.
               | We're all familiar that it's somewhat rare that a
               | technological advancement goes from no usage to film and
               | wide distribution in one step. New technologies are
               | distributed only to the rich precisely because they are
               | time and resource intensive to develop and can only be
               | feasibly prepared via a process which will inevitably
               | occur costs that the majority of humans will not be able
               | to meet. But you _need_ those first few rich people,
               | because the money they put in starts the feedback cycle
               | that would not be able to start otherwise. Ideally this
               | then begins a process of optimization which gradually
               | allows these products to become available to everyone.
               | 
               | Inequality is the price of innovation, but it doesn't
               | have to be paid forever.
        
             | nradov wrote:
             | The major increases in human lifespan have come from public
             | sanitation, food safety, vaccinations, antibiotics, and
             | trauma care. The rest of medicine has had only a small
             | impact.
        
           | ghodith wrote:
           | Imagine a world where immortality is given to 1% of the
           | populace per year such that in 100 years everyone is
           | immortal, but it is given in order of decreasing wealth.
           | 
           | Now imagine a world in which no one is immortal for 99 years,
           | but on the 100th year everyone gains immortality at once.
           | 
           | The latter is vastly more equitable, but to choose such a
           | world would be horrific in cost of lives.
           | 
           | I can imagine the dystopia that would come from an undying
           | elite ruling over a mortal underclass. However, in any
           | situation short of that extreme, I would never promote
           | anything that would slow the search for immortality.
           | Especially not for the mere bog standard modern conception of
           | _equity_ ; crab-bucket mentality here will only serve to keep
           | us all scrabbling in the dirt.
        
           | D-Coder wrote:
           | > It's inevitable that access to "defeating the dragon" would
           | be available to only the most affluent in society, whom have
           | also led the most comfortable lives.
           | 
           | I don't see that it's inevitable at all. (a) The solution may
           | be very affordable. (b) Any government that does not get the
           | treatment to all citizens is likely be voted out or
           | overthrown.
        
         | ijhuygft776 wrote:
         | The environmental conditions are unknown but they _know_ that
         | they are the cause....
        
           | alpaca128 wrote:
           | If the fish can't be normally observed procreating at times
           | then it's quite obvious it needs different conditions.
        
             | ijhuygft776 wrote:
             | are they environmental conditions though?
        
               | iakov wrote:
               | What else can be a factor? Fishies libido?
        
         | charrondev wrote:
         | It's a well written fable. There's a pretty well narrated
         | animation of the fable as well [0].
         | 
         | [0] https://youtu.be/cZYNADOHhVY?si=3zJIGBlfWmnml5i-
        
         | cubefox wrote:
         | Unfortunately he doesn't address overpopulation. Admittedly,
         | birth rates are declining rapidly.
        
           | optimalsolver wrote:
           | People would definitely put off having kids if they had
           | extended lifespans.
           | 
           | They're already doing it with our regular lifespans.
        
           | pie420 wrote:
           | There is an entire universe to fill, overpopulation is just
           | as worthy of worrying about as is running out of numbers.
        
             | cubefox wrote:
             | Currently there is only Earth to fill.
        
         | yieldcrv wrote:
         | Evolution doesn't choose these things and it isn't a conscious
         | choice with the organism
         | 
         | It's just random mutations selected for or we never get to see
         | a buffalofish, the latter happens far more often and is the
         | crux of evolution by natural selection: orders of magnitude
         | more species that died out
        
         | rtourn wrote:
         | I think Altered Carbon brought up the most chilling view of a
         | world without death. In that exploration only the rich are
         | immortal, because the poor can't afford immortality. Someone
         | being rich for hundreds of years will only cement their their
         | power, position, and their perspective. How do we feel if
         | Rockefeller were still alive and powerful? What if our old
         | kings never died? If any of them had a sexual perversion, what
         | if it continued for hundreds of years? Where does that road
         | lead?
        
           | unsupp0rted wrote:
           | I wonder if people really would ossify after hundreds of
           | years or eventually learn to be hyper-adaptable.
           | 
           | Current centenarians are a bad example, because their brains
           | and bodies are falling apart.
           | 
           | Some sci fi suggests that the fact of our living and dying in
           | just one century means we die as immature children.
           | 
           | Maybe it takes a thousand years or ten thousand years to
           | "know thyself" to any useful degree.
        
             | godelski wrote:
             | In a rather unpopular opinion, I think most people are more
             | of a product of their environments than we like to believe.
             | If you look at the rate at which social change happens and
             | public opinion about certain topics, it happens much faster
             | than new generations replace the old. A good example of
             | this is with same-sex marriage. Opinion changed rapidly and
             | I'm sure many have even forgot all the things said before
             | Obergefell v. Hodges. Certainly new generations have new
             | ideas and put pressures on the environment, but I think
             | there's too much weighting in most people's models of how
             | much change is held up and requires older generations to
             | exit the decision making process.
        
               | Georgelemental wrote:
               | > If you look at the rate at which social change happens
               | and public opinion about certain topics, it happens much
               | faster than new generations replace the old.
               | 
               | To the contrary, it happens exactly that fast.
               | https://scholars-stage.org/culture-wars-are-long-wars/
        
               | pie420 wrote:
               | This is so incorrect it's laughable. If you look at the
               | data, public opinion in america has changed almost
               | exactly in step with new generations emerging and old
               | generations dying. People almost never change their
               | opinion on political issues, they just die.
        
               | poulsbohemian wrote:
               | >A good example of this is with same-sex marriage.
               | Opinion changed rapidly and I'm sure many have even
               | forgot all the things said before Obergefell v. Hodges.
               | 
               | Do you live on one of the US coasts? Because if so, you
               | are probably right - before Obergefell, most people
               | didn't care about your private life and after Obergefell
               | it could all finally be out in the open. But in a big
               | chunk of this country, it really doesn't matter what the
               | courts decided because there is major political and
               | religious pressure that says that ain't ok. Don't pretend
               | for a moment that a wide swath of states wouldn't send us
               | straight back to 1863 if they could.
        
             | KineticLensman wrote:
             | > Some sci fi suggests
             | 
             | Jonathon Swift explored this idea in 1726, in Gulliver's
             | Travels, with the Struldbruggs [0] - decrepit immortals.
             | Struldbruggs also popped up in Larry Niven's Known Space
             | universe [1], albeit there as the name of a club for the
             | old and powerful (IIRC with an increasing minimum age to
             | keep out the young whippersnappers).
             | 
             | [0] https://en.wikipedia.org/wiki/Struldbrugg
             | 
             | [1] https://en.wikipedia.org/wiki/World_of_Ptavvs
        
             | m463 wrote:
             | I think people stop adapting lots earlier than the time
             | their body starts breaking down.
             | 
             | In fact, the body breaking down might be a reason people
             | become adaptable.
        
           | andromeduck wrote:
           | This is the premise of In Time (film) too.
        
             | BLKNSLVR wrote:
             | Yeah, but Altered Carbon does it immeasurably better from
             | all angles.
        
             | __MatrixMan__ wrote:
             | I've heard that "In Time" was ripped off from "Repent
             | Harlequin Said The Tictockman"
             | (https://www.d.umn.edu/~tbacig/cst1010/chs/ellison.html).
             | It's worth the 5 minutes it should take to read it, even if
             | you take 6 ;)
        
           | huytersd wrote:
           | Why specifically point out a sexual perversion. It seems like
           | the least of the bad things an authority figure like a king
           | could do.
        
             | BLKNSLVR wrote:
             | Epstein.
        
           | blargey wrote:
           | > what if only a tyrannical nobility could benefit from this
           | new technology, and it stayed that way forever?!
           | 
           | Yeah it goes without saying that's a bad thing, for any
           | technology. That shouldn't convince anyone that Logan's Run
           | is preferable.
        
           | somesortofthing wrote:
           | This is dependent on a world where immortality is expensive
           | because it's difficult to actually make someone immortal
           | rather than because it's difficult to figure out how to make
           | someone immortal. For all we know, immortality is as simple
           | as a one-time injection into an egg cell, and the challenge
           | is almost entirely in figuring out _what_ to inject.
           | 
           | Also, how much is the death of bad individuals actually
           | contributing to making the world a better place? It seems to
           | me like the various abuses of robber-barons and tyrants past
           | and present are perpetuated by institutions built around them
           | rather than their own personal capacity to affect the world.
           | A king in exile on a remote island or a Rockefeller driven to
           | bankruptcy can remain unchanged as a person while losing
           | virtually all of their capacity to impose their will on the
           | world, while a kingdom or corporation can keep going
           | centuries after the death of its leader if conditions stay
           | favorable.
        
           | sorokod wrote:
           | Nit, there is RD - real death in the altered carbon universe.
           | Happens when an individual's cortical stack is destroyed.
        
       | Solvency wrote:
       | How does this track with bioaccumulation of plastics and mercury
       | and other pollutants over such a long life?
        
       | verisimi wrote:
       | It must be their vaccination schedule
        
       | stevebmark wrote:
       | If you're curious to learn more, look into cold blooded vs warm
       | blooded animals and longevity. Cold blooded animals might give us
       | hints to slow aging in humans.
       | 
       | Energy expenditure might be related to longevity. Eating more and
       | exercising more (and the energy required to keep your core
       | temperature up) might kill you faster, maybe through free radical
       | production from metabolism.
        
       | huytersd wrote:
       | Aren't lobsters immortal if they never have an accident?
        
       | givemeethekeys wrote:
       | That one time a goldfish lived for more than 200 years:
       | 
       | https://en.wikipedia.org/wiki/Hanako_(fish)
        
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