[HN Gopher] Psychedelics researcher approached his death with ca...
       ___________________________________________________________________
        
       Psychedelics researcher approached his death with calm and
       curiosity
        
       Author : ianai
       Score  : 129 points
       Date   : 2023-11-05 12:26 UTC (10 hours ago)
        
 (HTM) web link (www.npr.org)
 (TXT) w3m dump (www.npr.org)
        
       | Arubis wrote:
       | For those so inclined, Tara Brach had a lovely interview with
       | Roland early this year: https://overcast.fm/+SWwgtYFDM
       | 
       | From the podcast summary:
       | 
       | Meditation, Psychedelics, Mortality: A conversation with Tara and
       | Roland Griffiths - Roland is a long-term meditator, a
       | psychopharmacologist and professor at Johns Hopkins, and a leader
       | in researching the clinical effects of psychedelics, including
       | their impact on those struggling with cancer, depression or
       | addiction. At the end of 2021, he discovered he had incurable
       | stage 4 Colon Cancer. This conversation explores the relationship
       | between meditation and psychedelics, and how they both can serve
       | profound spiritual awakening and deep inner freedom in the face
       | of mortality.
       | 
       | Information about the endowment fund: The Roland R. Griffiths,
       | Ph.D. Professorship Fund in Psychedelic Research on Secular
       | Spirituality and Well-Being.
        
         | jseliger wrote:
         | I'm not a psychedelic researcher, but I have taken
         | psychedelics, and I recently wrote "Strange trip: Psychedelics
         | and confronting the fear of death:"
         | https://jakeseliger.com/2023/09/25/strange-trip-
         | psychedelics..., which covers similar themes.
        
           | nekitamo wrote:
           | Your blog is deeply moving, thank you for posting the link.
           | When my time comes, I hope I accept it with the equanimity
           | and grace you display.
        
             | jseliger wrote:
             | Thank you and you're welcome, too!
        
           | ggpsv wrote:
           | A beautiful read, thank you for sharing. May you and your
           | partner be well.
        
             | jseliger wrote:
             | Thank you and you're welcome, too!
        
         | manuelmoreale wrote:
         | There's also this episode with Sam Harris that is worth
         | listening to: https://www.samharris.org/podcasts/waking-up-
         | conversations/p...
        
       | bobosha wrote:
       | I wish there was more support to not just decriminalize but
       | legalize psychedelics broadly. I know there are plenty of ongoing
       | clinical trials, but the collection of Psilocybin, LSD,
       | Mescaline, Ibogaine is genuinely a treasure chest and probably
       | the best thing that has happened to medicine in a long time, if
       | not ever.
       | 
       | Edit: i highly recommend watching Michael Pollan's "How to change
       | your mind" (Netflix documentary).
       | https://www.youtube.com/watch?v=X8LRb4jfZ9g
        
         | sedivy94 wrote:
         | I'm not going to be that guy, because I don't read nearly
         | enough to begin with, but I read the book and... it was
         | amazing. I have a deep appreciation for the psychedelic
         | experience and reading his trip reports brought me, a 30 year
         | old man, to tears.
        
         | zozbot234 wrote:
         | What do psychedelics achieve here that ordinary meditation as
         | in e.g. vipassana does not? They seem like a pointless
         | shortcut, and potentially a problematic one. If the
         | hallucinatory dynamic is specifically what you care about,
         | that's also typical of perfectly ordinary experiences such as
         | dreaming, or even just drifting in and out of sleep. What
         | "treasure" are we gaining by dosing the brain with chemicals,
         | that we couldn't otherwise?
        
           | freedomben wrote:
           | This is very similar to "what do antidepressant medications
           | achieve that regular diet and exercise do not? "
           | 
           | Assuming equal efficacy is possible in the first place, and
           | assuming every human is even capable of reaching those
           | levels, there are people who can't spend the sometimes years
           | it takes to practice meditation to a point where they can
           | achieve psychidelic efficacy.
           | 
           | Why not have both available and you can do you?
        
           | cyberpip wrote:
           | The argument here is that psychedelics are more than
           | "chemicals" and comparing them to drifting in and out of
           | sleep is not a real comparison. Can't argue against them
           | sometimes being problematic though, of course, but the
           | argument here isn't acknowledging the real psychedelic
           | experience. If curious, check out some reports on
           | https://www.youtube.com/@Vivec
        
             | zozbot234 wrote:
             | What I compared to drifting in and out of sleep was merely
             | one effect of psychedelics that people tend to be curious
             | about, namely hallucination. Moreover one can very much
             | approach these dreamlike states with a meditation-like,
             | non-judgmental, non self-centered mental posture, and this
             | is going to make their effects even clearer.
        
           | explaininjs wrote:
           | Yes. As captured by the Big Lez Show:
           | 
           | > Donny: Panaeolus cyanescens, psychadellic.
           | 
           | > Lez: What do they do to ya?
           | 
           | > Sassy: Take you on a journey of self-discovery, you find
           | out who you really are, this and that.
           | 
           | > Donny: Either that or you trip out for four or six hours.
           | But in our current situation this will be really good for us,
           | gunna heighten our senses so we'll be way more in tune with
           | our surroundings.
           | 
           | > Lez: These heighten senses?
           | 
           | > Donny: They heighten senses you didn't even know you had.
           | 
           | > Lez: Have we got more than five?
           | 
           | > Donny: So many.
           | 
           | > Lez: How do I turn them on?
           | 
           | > Sassy: Meditate.
           | 
           | > Donny: Yeah meditation's probably the best way. Or, trip
           | out on some psychedelic mushrooms.
           | 
           | https://www.youtube.com/watch?v=HPeSVlk6E70
        
           | omginternets wrote:
           | I think the transcendent experience has a lot to do with it.
        
           | lukasb wrote:
           | I love meditation and practice daily, but not everyone can do
           | 1 hour a day (Goenka recommends two) and one ten day retreat
           | a year.
           | 
           | If one or two guided trips can transform someone's
           | relationship to death, that's hugely valuable.
        
           | oooyay wrote:
           | > What do psychedelics achieve here that ordinary meditation
           | as in e.g. vipassana does not?
           | 
           | I actually don't think it's worth comparing the two. They
           | achieve a similar end goal depending on your intentionality
           | but I don't think it's fruitful to say one is better than the
           | other.
           | 
           | > They seem like a pointless shortcut, and potentially a
           | problematic one.
           | 
           | Psychedelics certainly have a higher ability to be abused.
           | People need to be educated on looking at their family mental
           | health history, they need an informed trip sitter, and they
           | need to be well informed on what the experience will entail.
           | 
           | On the other hand, how many guru cults that incorporate
           | meditation as a form of psychological warfare and isolation
           | have we witnessed in our lifetimes? The people who are
           | casually allowed to walk around and profess themselves as
           | prophets or gurus is highly adjacent to the consequences of
           | ill-informed ego death and return in the psychedelic space.
           | 
           | > If the hallucinatory dynamic is specifically what you care
           | about, that's also typical of perfectly ordinary experiences
           | such as dreaming, or even just drifting in and out of sleep
           | 
           | Psilocybin, LSD, and DMT are _nothing_ like dreaming. They
           | 're very vivid experiences. They can rip you out of your
           | rooting in this reality which is why, imo, they're not good
           | to do unless you have an informed trip sitter who can ensure
           | your mental, emotional, and physical safety. That's what also
           | makes them powerful teachers in the way of perspective; imo,
           | it's not that you're "unlocking secrets to the universe"
           | during a trip, moreso you've been granted a perspective
           | outside of your sense of self that is difficult to achieve
           | otherwise. Depending on the dose it could also be total
           | dissolution of the ego. These things wear off, of course, but
           | someone who can help you do a "soft landing" in the case
           | where you run into some trauma makes a huge difference. The
           | things you process _afterward_ are where  "the work" is done.
           | 
           | > What "treasure" are we gaining by dosing the brain with
           | chemicals, that we couldn't otherwise?
           | 
           | You could meditate until your ego dies and likely achieve
           | many of the same machinations from what I've read from
           | peoples testimonies. Again, the work isn't done _during_
           | meditation, it 's how you decompose your experience and
           | incorporate it into your life later. Psychedelics are the
           | same, just a different mechanism that you cannot choose to
           | say "I'm done" halfway through.
        
         | vorpalhex wrote:
         | Psychdelics can and do kill meaningful amount of people, almost
         | exclusively due to injuries while under their affects.
         | 
         | 147 psychedelic deaths over three years -
         | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523208/
         | 
         | I'll have to find a youtube video but there's a good one with
         | one of the psychdelic guru's describing a trip where had mis-
         | dosed (he didn't realize the mushrooms he was consuming were
         | significantly stronger than anticipated) and he ended up stuck
         | in a "loop" of not being able to start his car.. for three or
         | four hours. His exprience was distressing but not much of an
         | injury, but he then delves into a story about how a similar
         | loop resulted in one of his friends dying from repeatedly
         | falling into cement.
        
           | grogenaut wrote:
           | How did the guy end up with 2 different neophyte people they
           | were instructing in dangerous situations and sharing that.
           | Let's not mince word, if the first had started the carit
           | would be a dangerous situation. In college with alcohol wed
           | stick a sober watcher over the pre-frosh who decided to drink
           | the first time away from home.
           | 
           | Having just one go slightly sideways would make me really
           | cautious. I was because freshman year I found some random
           | pre-frosh who had hidden in a closet cause they thought
           | they'd be in trouble (they were not, wet campus) who needed
           | help.
        
           | freedomben wrote:
           | If 147 in 3 years is "a meaningful amount of people" then
           | we're gonna need to ban a lot of other stuff to stay
           | consistent.
        
             | debo_ wrote:
             | Like lakes, for example.
        
               | jvm___ wrote:
               | Stairs
        
               | Turing_Machine wrote:
               | Bathtubs.
        
               | huytersd wrote:
               | Running
        
               | quaddo wrote:
               | Earthquakes.
        
           | zoklet-enjoyer wrote:
           | Why was he trying to start his car? I'm glad he couldn't
           | figure it out otherwise he could have killed someone. This is
           | a personal responsibility thing.
        
           | rpearl wrote:
           | The paper you linked does not say what you claim it says.
           | 
           | Instead, it appears to investigate psychoactive drug deaths
           | not to do with overdose.
           | 
           | There appear to be no "traditional" psychedelics
           | (serotonergic hallucinogens like LSD, psilocybin, etc)
           | covered here _at all_ except perhaps one death categorized as
           | a "hallucinogen", which is definitely a lot less than 100% of
           | the 147 deaths investigated.
        
           | Projectiboga wrote:
           | You misquoted the title, which is actually, "Fatal injuries
           | while under the influence of psychoactive drugs". There was
           | no psychedelic fatalities other than 1 MDMA & alcohol one.
           | Those were all booze, and other drugs. I'm not saying there
           | are none, it's just the death rate during psychedelic trips
           | is a actually lower than for sober people. On average those
           | drive less and are often in group settings, so it's more
           | those substances don't alter the death rate and the safety is
           | provided by the context of not driving as much as typical,
           | and not working with machinery.
        
         | almatabata wrote:
         | When you say legalize broadly i guess you mean allow doctors to
         | prescribe it to their patients with proper protocols and not
         | just allow anyone to buy it over the counter?
        
           | fullspectrumdev wrote:
           | When I talk about legalising drugs, I mean being able to buy
           | them with the same level of control as beer or cigarettes.
        
             | gymbeaux wrote:
             | Because beer and cigarettes are both mind-altering drugs
             | yet get a pass because of mostly-economic reasons.
        
               | freedomben wrote:
               | Not economic, historical. It's purely because both were
               | things before the puritan movement (which still greatly
               | impacts society today) and people are already familiar
               | with them. If alcohol were discovered today, there's no
               | way in hell it would be legal
        
               | almatabata wrote:
               | Do cigarettes have such a big mind-altering effect?
        
             | almatabata wrote:
             | thanks for clarifying.
        
         | huytersd wrote:
         | I understand that people are very different because if I took
         | mushrooms when I was terminally ill, I would have a trip so bad
         | it would break my mind.
        
           | ngai_aku wrote:
           | Did a previous trip lead you to this belief are you just
           | speculating on what your experience would be like?
        
             | huytersd wrote:
             | I've had one bad trip (not terrible) when I was expecting
             | some bad news. I'm basing it off of that experience. I've
             | had a dozen other good trips but I was always careful to
             | make sure I was in a good headspace before doing it.
        
       | pizzafeelsright wrote:
       | How is this different from escaping problems through drug use?
        
         | wombat-man wrote:
         | Psychedelics are so different from alcohol and narcotics, idk
         | how to explain. Instead of being distracted or numbed from your
         | problems, you may concentrate on them deeply and from new
         | angles.
         | 
         | But delusions can occur too. Ymmv.
        
         | freedomben wrote:
         | Is it fair to infer that you have a value judgment on escaping
         | problems through drug use, and think it's wrong or bad?
         | 
         | If so, why?
        
           | pizzafeelsright wrote:
           | Yes. Instead of escaping, let's solve the problem instead.
        
             | freedomben wrote:
             | Why do you think the former precludes the latter?
             | 
             | This seems to be like if someone comes to a doctor with an
             | arrow stuck through him, someone saying "don't give him any
             | pain killers, that's bad. Just take the arrow out so the
             | problem is solved."
             | 
             | You should obviously remove the arrow to correct the root
             | cause, but you don't need to deny the patient pain killers
             | in order to do so. Judging him morally or legally for
             | wanting them doesn't make sense to me, short of claiming
             | that an unprovable all powerful being who talks to man only
             | through extremely unreliable and non reproducable channels
             | has revealed to us that it's actually a sin.
        
               | gehwartzen wrote:
               | For me it depends on context; Pain exists for a purpose
               | (i.e don't put wait on a broken leg otherwise you could
               | extend healing time or make things worse) but if
               | technology allows us to mitigate the potential problems
               | (i.e fixing the bone and apply a cast will allow you to
               | walk but not add strain) getting ride of pain in the
               | meantime is probably a net good.
               | 
               | If you have chronic pain of some sort and you use
               | substances to mask that pain the root problem hasn't been
               | addressed and still exists, you just won't be aware of
               | it. If loosing awareness (which at its simplest is what
               | painkillers do) of the ongoing problem is okey with you
               | by all means take a substance to mask it, just don't be
               | surprised when the original problem grows worse latter.
               | 
               | Im okey with people masking or not masking. It should be
               | a personal choice free of judgement.
               | 
               | There are two guys and both are extremely depressed. One
               | guy decides to seek out a therapist and has a meeting set
               | for two weeks from now, the other guy decides to take
               | MDMA/LSD/shrooms (or whatever) every day. He feels
               | amazing and is living his best life every day. The first
               | guy is super depressed day to day but maybe the therapy
               | will help...
               | 
               | The next week they are on a plane together that crashes.
               | Who made the better decision?
               | 
               | Alternatively they don't die and instead live decades
               | more. The first guy got to the root of his issues and
               | lived a very happy life while the second eventually
               | burned out and fell into even deeper depression for his
               | remaining years. Who made the better decision?
               | 
               | It is not fair for us to judge others on how they would
               | like to treat their own bodies and minds. We don't know
               | the totality of their path through life.
        
               | jonathanlb wrote:
               | Your point is taken, but it's not quite apples-to-apples.
               | 
               | Therapy can be a deep healing process or a superficial
               | fix, just as psychedelics like shrooms, LSD, or MDMA can
               | be used daily by some (suggesting a shamanic lifestyle,
               | in my opinion) or lead to profound insights in a single
               | ayahuasca trip for others.
               | 
               | It's true we shouldn't judge what works for someone
               | without knowing them well, and even then, we can only
               | offer suggestions. But when comparing, we should ensure
               | we're not misrepresenting the situation, whether
               | intentionally or not.
        
             | jamiek88 wrote:
             | How do you solve stage 4 terminal cancer?
        
               | pizzafeelsright wrote:
               | My parent was diagnosed with stage 4. We tried to help
               | and ultimately we all accepted death was near.
        
               | rpearl wrote:
               | The problem to be solved in this case is unnecessary
               | distress and pain about one's inevitable death.
        
               | wholinator2 wrote:
               | And how do you solve that
        
               | dieselgate wrote:
               | One common solution is the hospice system. There's no
               | silver bullet for any of this and it's a bit irksome see
               | so many comments treating this like a "5 whys" exercise
        
             | omginternets wrote:
             | The problem here is acceptance of one's mortality. What
             | solution do you propose?
        
               | pizzafeelsright wrote:
               | Accept it fully.
        
               | omginternets wrote:
               | Quite. How do you propose to do that?
               | 
               | And more importantly, how do you propose people who
               | struggle to do this reach that acceptance?
        
               | The_Colonel wrote:
               | The article talks about that and it seems the patient did
               | accept the mortality fully:
               | 
               | > It wasn't that he was filled with spiritual language
               | like, "God's gonna save me." No, it was an acceptance for
               | his condition and a reassurance to the people he loved
               | most, that everything was OK, everything was as it should
               | be, and they felt uplifted by that.
        
               | wholinator2 wrote:
               | It seems you're nearing the message. How does one accept
               | that fully? What do we do in the face of struggles with
               | what may be the greatest struggle a human being ever
               | faces? Could there be some technique that could help?
               | What would that technique look like? Could it include the
               | ingestion of a substance? If ingesting said substance
               | along with guided meditation was vastly superior to all
               | other techniques of death acceptance, would that be
               | avoiding the problem with drugs?
               | 
               | I think what you're not understanding is that taking the
               | drug _is_ the death acceptance technique. It _is the
               | thing_ that allows these people to quickly transition
               | into peace. Do you have a better way? Could you please
               | share that so all of our dying family members could
               | finally have the simple solution you seem to be aware of?
        
               | zozbot234 wrote:
               | The drug is just exposing these subjects to the
               | experience of living fully in the present moment. This is
               | not something that can be done as "one weird trick", it
               | requires true spiritual maturation-- and yet, people who
               | haven't learned how to do this are literally dying every
               | single day, whether they realize this or not. Whatever
               | time is past for them, is in Death's hands already. They
               | can choose to dwell on this, or just not bother and live
               | life to the fullest as best they can.
        
               | omginternets wrote:
               | We are lucky enough to have two tools at our disposal:
               | 
               | 1. Cultivating the spirit. This is slow and has a high
               | abandonment rate, but it is second-to-none in terms of
               | living a fulfilling life. It is worth pursuing, but is
               | unfortunately ill-suited for rescuing people who are in
               | the midst of a mental-health emergency. It should be
               | thought of as "prevention".
               | 
               | 2. Cultivating psychoactive substances. This is riskier
               | than the first option, but it has two main advantages:
               | (1) with some precautions, it is immensely helpful in
               | connecting people with their spiritual lives and (2) in
               | an emergency, it is reliably effective. This is on par
               | with the discovery of antibiotics, in terms of medical
               | significance. It should be thought of as "intervention".
               | 
               | Why anyone would willingly renounce the use of either? On
               | what principle? This is obscurantism.
        
             | barbs wrote:
             | That's ideal, but some people don't have the resources to
             | do that.
        
         | temp0826 wrote:
         | Because it can be about _facing_ the problem, with assistance
         | of an altered state opened by the psychedelic. They are tools
         | in the right context.
         | 
         | (Disclaimer, working at ayahuasca retreat centers for the last
         | 3 years so maybe biased as to what that context actually is :))
        
         | martopix wrote:
         | Because the kind of drug use you're thinking of means
         | _addiction_ to a substance (one that typically numbs you or
         | makes you feel unnaturally happy). Here he 's discussing about
         | people improving their condition after a single dose.
        
         | specproc wrote:
         | IMHO, it's perfectly fine, positive even to escape one's
         | problems with drug use. You just can't do it every day.
        
           | gehwartzen wrote:
           | If one could do you think that would be a problem?
        
             | specproc wrote:
             | I guess depends on the drug and the problem.
             | 
             | Daily use of lots of substances, e.g. alcohol, isn't
             | necessarily a bad thing in itself (though it really can
             | be), but if it's to escape a problem then there's a serious
             | risk there. As the above suggested, the problem also
             | remains unresolved.
             | 
             | So yeah, I don't think a person self-medicating on a daily
             | basis is always problematic, but it's never worked out well
             | for me, and it's not something I'd advise.
             | 
             | My original point was really that getting out of one's head
             | once in a while can give a fresh perspective on a problem.
        
             | JasserInicide wrote:
             | Depends on the drug.
             | 
             | Caffeine? Probably the most used and least worst, could
             | still cause sleep disruptions.
             | 
             | Weed? Could be a problem. It's very easy to get mentally
             | addicted to it and turn you into a bowl of mush, but if
             | you're using it in medical doses I imagine it's less so.
             | 
             | Microdosing LSD? Depends from person to person. I think
             | using it too often isn't good for the heart.
             | 
             | Alcohol? Absolutely a problem, even if the worst side
             | effects take years to manifest.
        
         | dbtc wrote:
         | Confronting problems with medicinal assistance.
         | 
         | Intention makes a difference.
        
         | 0max wrote:
         | Most folks associate taking psychedelics and hanging out in a
         | living room, out in nature, being at a club, festival or
         | warehouse. The difference here is that the dugs are being used
         | in a directed mental health setting with process and procedure.
         | This has roots going back to Native American spiritual and
         | communal experiences like the ayahuscaeros of today.
         | 
         | Joe Rogan's old content postulates that religion as we know it
         | today was formed from psychedelic experiences. For example, the
         | bush that burned in front of Moses was acacia and widely known
         | in the levant to have psychedelic properties
         | 
         | https://www.youtube.com/watch?v=fwV8_Oc0EuY
        
         | pacificmaelstrm wrote:
         | Simple answer, It's not.
         | 
         | Approaching a horrible situation with calm acceptance and
         | resignation is pathological insanity.
         | 
         | Don't let anyone tell you different.
        
       | ganzuul wrote:
       | "This life is only a prelude to eternity." - Seneca
       | 
       | You can mostly avoid upsetting people with the God language by
       | talking about love of truth instead.
        
         | nwiswell wrote:
         | Can't we say, with nearly as much accuracy, that this life is
         | an epilogue to eternity?
        
           | dartos wrote:
           | I don't think so. Eternity, by definition, never ends, so
           | this life couldn't come after the end.
        
             | nwiswell wrote:
             | Mmm. That presupposes infinite linear time. By most
             | accounts, "this life" bookends about 13.7 billion years of
             | linear time, but how do we understand the state of things
             | before that?
             | 
             | How could we understand the state of things once the heat
             | death of the universe is a distant cosmic memory, and
             | entropy no longer provides an "arrow of time"?
        
           | jareklupinski wrote:
           | it's a stop along the way from infinity to forever
           | 
           | stretch your legs :)
        
       | ipnon wrote:
       | Griffiths was the driving force behind mainstream acceptance of
       | psychedelic medicine with his work at Johns Hopkins. He showed
       | that psilocybin was not only effective but was the most effective
       | treatment for terminal psychiatric care and addiction, and he did
       | it all within the mode of academic medical research. I hope his
       | death was painless. A great scientist deserves no less.
        
         | unihd2kno wrote:
         | it was his character in combo with the delics. this kind of
         | treatment can only be taught if aspiring teacher/psych/shrink
         | is super-rational and NOT at all if said person is rational
         | (=pseudo-rational)
        
       | ggpsv wrote:
       | This is not mentioned in the article, but upon learning about his
       | prognosis Griffith worked on establishing an endowment to support
       | the continued research on psychedelics and "secular spirituality
       | and well-being".
       | 
       | I recommend watching Griffith's video message [0] where he talks
       | about the research and reflects on his condition. I also
       | recommend the conversation with Sam Harris that someone else
       | shared in a comment.
       | 
       | [0]: https://griffithsfund.org/vision/
        
       | rjbwork wrote:
       | Sam Harris did an interview with him last year that was pretty
       | good on the topic of psychedelics and death.
       | 
       | https://www.samharris.org/podcasts/making-sense-episodes/306...
        
       | georgex7 wrote:
       | Beautiful
        
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