[HN Gopher] Kangaroo tendons could rebuild human knees better, s...
       ___________________________________________________________________
        
       Kangaroo tendons could rebuild human knees better, stronger
        
       Author : geox
       Score  : 147 points
       Date   : 2023-07-19 12:07 UTC (10 hours ago)
        
 (HTM) web link (lighthouse.mq.edu.au)
 (TXT) w3m dump (lighthouse.mq.edu.au)
        
       | xwdv wrote:
       | Don't know why people have objections to this, we already use
       | bovine and pig valves in hearts, saves lives, improves health. I
       | am comforted by the fact that if I ever need to rebuild a knee
       | someday in the future, kangaroo tendons may be an option, so I
       | can stay off the bench and stay on the basketball court.
        
       | FpUser wrote:
       | >"undisclosed" materials for compatibility"
       | 
       | Should not it invalidate the patent?
        
       | reocha wrote:
       | This is very cyberpunk.
        
       | makeitrain wrote:
       | Question: Would my new kangaroo enhanced legs disqualify me from
       | the Tour de France?
        
       | jaggederest wrote:
       | Interesting related article I think I saw here a while ago:
       | 
       | Healing of acute anterior cruciate ligament rupture on MRI and
       | outcomes following non-surgical management with the Cross Bracing
       | Protocol
       | 
       | https://bjsm.bmj.com/content/early/2023/06/13/bjsports-2023-...
       | 
       | TL;DR they braced the knee at 90 degrees flexed and saw evidence
       | of some healing in 90% of enrolled patients after 3 months
        
         | taneq wrote:
         | This seems to be saying that a completely torn ACL will
         | actually reconnect if the knee is kept immobilized? I did my
         | ACL and in the MRI it was just _gone_ aside from a fuzzy puddle
         | on top of my tibia, it 'd be incredible if that could regrow.
         | 
         | > knee immobilisation at 90deg flexion in brace for 4 weeks,
         | followed by progressive increases in range-of-motion until
         | brace removal at 12 weeks
         | 
         | Compared with an ACL reconstruction with Gracilis tendon graft
         | (the procedure I had), I wonder if complete immobilization for
         | four weeks might do more damage than just having the surgery. I
         | was limping but still loading up the leg as much as possible
         | for four weeks after the accident and then off it for a week
         | after surgery, and the muscle loss and general degredation was
         | severe. It took months of physio and most of a year of exercise
         | to rebuild back to ~95%. Taking 2-3 months to get weight back
         | on it sounds light it could be worse overall.
        
           | throw1234651234 wrote:
           | If it grows back "correctly", that's still way better than
           | surgery, since who knows if they "get it right".
        
         | throw1234651234 wrote:
         | Is "rupture" a full tear? The "common knowledge" is that
         | "ligament full tears can't heal". In fact, 10 years ago, people
         | were told that partial tears can't heal either, and you might
         | as well not bother.
        
           | trogdor wrote:
           | >Is "rupture" a full year?
           | 
           | Yes. Complete discontinuity of ACL fibers on MRI.
        
         | pr0zac wrote:
         | Isn't this common treatment already? Don't actually know, just
         | remember my stepmom and everyone else I've known that had knee
         | surgery getting a cool knee scooter thing to roll around on for
         | the months long recovery period.
        
           | jaggederest wrote:
           | No, this is _instead of_ surgery, as far as I can tell just
           | splinting it bent at 90 degrees to allow it to heal.
        
           | swader999 wrote:
           | My wife healed her fully severed mcl without surgery. It's
           | difficult but possible. You have to be really disciplined and
           | follow the protocol.
        
             | jaggederest wrote:
             | From what I gathered from the article abstract I posted
             | above, this is unique because it's a protocol for healing a
             | fully severed ACL, where the MCL heals much more readily
             | than the ACL apparently for reasons of blood supply and
             | positioning.
             | 
             | I love it when doctors can use conservative treatment to
             | avoid the need for surgery though, very exciting when a
             | natural process can do the work.
             | 
             | If you have any anecdotal discussion from your wife's
             | experience I'd be interested to hear more about it - I
             | haven't banged up my knees yet but it's just a matter of
             | time, already down some functionality in an ankle.
        
               | swader999 wrote:
               | Yes, although if you have a few million and access to a
               | daily MRI you can even heal a PCL this way. See the
               | Connor McDavid documentary "Whatever it Takes".
               | 
               | For my wife, it was strict bracing at specified angles
               | with forced stretching to retear the tendon at periodic
               | intervals as it healed. She was on advil and a cryo cuff
               | immediately after injury which really helped. I'd
               | recommend having a cryo cuff on hand or a plan to quickly
               | get one if knee injuries are likely in your future.
               | 
               | Look into red light therapy for ankle, for example:
               | https://a.co/d/7CPLFkl
        
         | steve76 wrote:
         | [dead]
        
         | 5555624 wrote:
         | Discussed at the time:
         | https://news.ycombinator.com/item?id=36594634
        
       | TOMDM wrote:
       | One assumption this skips over is that it's okay to put athletes
       | on the field with ligaments 6 times stronger than human baseline.
       | 
       | Of course this is a phenomenal treatment assuming it works as
       | planned, but isn't there a performance enhancement angle that
       | needs to be considered for it's inclusion in professional sports?
        
         | swarnie wrote:
         | The Enhanced Games will be stoked for this.
        
           | chongli wrote:
           | Like the old SNL sketch: The All-Drug Olympics!
        
         | williamdclt wrote:
         | I'm okay with dealing with this problem when it comes, I
         | definitely do not consider it a good reason to slow down
         | medical progress. I'd rather sport adapts to medical progress,
         | not the other way around!
        
         | kingkongjaffa wrote:
         | I for one welcome tendons of a kangaroo, teeth of a beaver,
         | arms of a gorilla.
         | 
         | viva la meta-human!
        
           | HeyLaughingBoy wrote:
           | Good luck getting dates!
        
         | hef19898 wrote:
         | I don't think so, the tendons make the knee potentially more
         | stable, the performance so comes from the muscles. And it
         | requires surgery, usually that kind of surgery is hard on the
         | body, and requires extensive physio therapy and training
         | afterwards.
         | 
         | So, the kangaroo tendons are potentially better than
         | traditional implants, the question you pose so is whether or
         | not they are better than the original, human ones. And I
         | somehow doubt that, but I am just a semi-engineer with a
         | ruptured, but still working, knee and not a physician.
        
           | throw1234651234 wrote:
           | This surgery has a very long recovery time. The ligaments are
           | just part of the story, the bigger risk is the cartilage in
           | the joint - if it tears, good luck, we have nothing to fix
           | it. Expensive stem cell therapy maybe kind of works. CPM
           | (continuous passive motion) sort of works over years, and
           | then there are the cripple-you-for-life titanium joint
           | replacements surgeries.
           | 
           | In short, this is far, far from being a concern, as cartilage
           | will fail even if the ligament can take it. Similar issue as
           | steroid-user muscle growth outpacing tendonds.
           | 
           | Medicine can't repair anything. I will repeat this for the
           | 1000th time, if you think we have tech realize that we -
           | can't fix an artery, re-attach a nail to the nail bed, fix
           | some crystals on teeth (enamel), regrow hair, etc, let alone
           | re-attach a nerve (though we do bypasses now). Basically,
           | people way overestimate the reality of what they can do when
           | they hear 3d organ printing myths.
        
           | pmontra wrote:
           | I wonder if human muscles can pull those stronger tendons as
           | they should to walk and run normally. Probably the surgeons
           | can weaken them a bit before the implant.
        
           | [deleted]
        
           | TOMDM wrote:
           | That's my thinking too, but I am left wondering if athletes
           | with this implant will be able to pull riskier corners
           | knowing that their knees are unlikely to give this time.
           | 
           | I look forward to finding out either way
        
         | matwood wrote:
         | > One assumption this skips over is that it's okay to put
         | athletes on the field with ligaments 6 times stronger than
         | human baseline.
         | 
         | I would love this, if only so I have less chance of going
         | through a fix again. I received a patellagraph to fix a torn
         | ACL, and the rehab is what makes it such a PITA. It took 9ish
         | months to be cleared for sports again, and I didn't feel
         | confident in my knee until 18 months or so.
        
         | jpeloquin wrote:
         | Across species, tendon strength is strongly correlated with
         | modulus (normalized stiffness). Greater stiffness has the risk
         | of reducing range of motion. When a graft is used it is
         | intended/hoped that the graft will remodel over time to become
         | more similar to the original tendon's properties, which match
         | what the entire organ system needs to function properly. Nor
         | does a stronger graft mean that the connection between the
         | graft and the bone will be 6x stronger. 6x stronger might also
         | be optimistic; prior work suggests more like 2x stronger and
         | stiffer.
         | 
         | https://pubmed.ncbi.nlm.nih.gov/23599401/
        
         | Brendinooo wrote:
         | It becomes a problem if your post-college Tommy John requires
         | you to get a kangaroo tendon to be competitive in MLB. Not sure
         | how you solve that problem in a fair and repeatable way though.
        
       | pfannkuchen wrote:
       | Should genetic engineering on humans ever become feasible to the
       | point where you can make large changes to the body plan, I wonder
       | if reverting bipedalism would be easier than fixing all of the
       | problems it causes (such as, I assume, knees, due to taking all
       | of the load on half of the limb joints, but, also, back problems,
       | etc). With human computer interaction technology advancements, we
       | may eventually move beyond needing hands at all, anyway.
        
         | HeyLaughingBoy wrote:
         | Bipedalism doesn't cause problems. Sitting on your ass all day
         | and then occasionally doing stuff that overstresses your now-
         | weakened joints causes problems.
        
         | tcoff91 wrote:
         | This comment is peak HN. Like it's so absurd that it feels like
         | it must be satire.
        
         | adrian_b wrote:
         | When predictable genetic engineering of animals will become
         | possible, there will be no difficulty in growing both two hands
         | and four legs, like in the mythical Centaurs.
        
           | pfannkuchen wrote:
           | Not necessarily. That is like saying "when predictable
           | engineering of bridges becomes possible, there will be no
           | difficulty in creating a floating-in-air bridge". Engineering
           | challenges still exist. My point is whether going to a more
           | standard body plan is an easier engineering problem than
           | fixing the design flaws in the nonstandard human one.
        
             | adrian_b wrote:
             | Your counterexample is not valid. There are reasons why a
             | "floating bridge" would not be easy to make, but the fact
             | that all the vertebrates with jaws that exist today have no
             | more than four paired limbs is just a historical accident
             | and only small changes in their body plan would be
             | necessary to make one with six paired limbs or even with
             | much more.
             | 
             | In some vertebrates, i.e. amphibians, it is very easy to
             | generate supernumerary limbs without any genetic
             | engineering, but just by manipulating the embryos.
             | 
             | Due to defects in the development of the embryo, birds or
             | mammals and even humans are sometimes born with polymelia,
             | i.e. with extra legs, and some of them succeed to have a
             | relatively normal life.
             | 
             | https://en.wikipedia.org/wiki/Polymelia
             | 
             | The purpose of predictable genetic engineering would be to
             | ensure the development of a body precisely into a form
             | optimized for a certain purpose. Obtaining random monstrous
             | forms is easy even today, by using various mutagen agents
             | and/or embryo manipulations.
        
               | pfannkuchen wrote:
               | The problem isn't generating something with a certain
               | body plan, I agree that is easy. The problem is achieving
               | a design without common or significant mechanical
               | problems over the lifespan of the organism. Can we assert
               | that, in your example, animals with extra limbs don't
               | have problems on par with the back or knee problems of
               | bipeds? I don't think we can?
        
               | adrian_b wrote:
               | It is very unlikely that predictable genetic engineering
               | for animals will become possible earlier than twenty
               | years from now and a time between 50 years and 100 years
               | from now seems most likely.
               | 
               | We are still very far from completely understanding how a
               | single nucleated (eukaryotic) cell works. After
               | understanding a cell we should first be able to
               | completely understand simpler multi-cellular living
               | beings like fungi and plants. The animals are the most
               | complex and there is no doubt that they will be the last
               | for which it will become possible to change some genes
               | and then predict with certainty what kind of animal will
               | develop from such a modified cell.
               | 
               | In any case, when that will happen it will be possible to
               | design the body of an animal, within certain constraints,
               | like we design now any complex machine. Bad designs will
               | always remain possible, but good designs should easy
               | avoid mechanical problems in the legs. By that time the
               | simulation possibilities should be much better than
               | today.
        
       | rco8786 wrote:
       | What if the "bionic man" from SciFi is not robots and
       | nanomaterials but actually just us borrowing things from nature
       | that happen to work better than the human version
        
         | bryanmgreen wrote:
         | A menagerie of animal-part patchwork humans sounds like a great
         | time!
        
       | mrweasel wrote:
       | One has to be rather careful about the wordings of such
       | announcement. I keep thinking "Dr. Nick want's to replace bits of
       | my mom body with kangaroo parts.... I wonder how my dad feels
       | about that?".
        
         | merth wrote:
         | jumpy?
        
       | no_wizard wrote:
       | Is it possible to farm Kangaroos for this purpose? Perhaps its
       | brutal to suggest, but I imagine hunting wild Kangaroos is not
       | what we want here, as their numbers are already in decline, IIRC.
       | 
       | Can the rest of a Kangaroo be used in some productive way? I'd
       | honestly feel ethically bad that we are killing Kangaroos just
       | for their muscle tendon in certain areas
        
         | mrits wrote:
         | I was under the impression that Kangaroos were an overpopulated
         | nuisance.
        
         | senectus1 wrote:
         | The bloody things breed like rabbits... you dont need to farm
         | them.
        
         | ceejayoz wrote:
         | > Can the rest of a Kangaroo be used in some productive way?
         | I'd honestly feel ethically bad that we are killing Kangaroos
         | just for their muscle tendon in certain areas
         | 
         | From the article:
         | 
         | > It was important to Dr Hartnell that no kangaroos were killed
         | expressly for his research, and this has remained his practice
         | throughout his investigations: all of the work has been done
         | only using kangaroos that have either been culled for reasons
         | of population control or harvested for meat.
         | 
         | Kangaroo populations are fine; culling is done to keep them
         | from overpopulating. Similar to deer in the US.
         | 
         | https://www.theguardian.com/environment/2019/jul/12/koala-ka...
        
       | Zigurd wrote:
       | Excuse me while I go to Truth Social and create a moral panic
       | about trans women with superhuman knee tendons ruining college
       | basketball.
        
         | cmrdporcupine wrote:
         | Bold of you to assume someone hasn't already created that
         | thread/meme.
        
       | light_hue_1 wrote:
       | They claim they can prevent them from being rejected with their
       | "special sauce" which they won't reveal.
       | 
       | What else can this be other than washing away all of the cells
       | and leaving behind only the scaffolding? Decellularization is
       | already a thing for tendon xenografts. Maybe they have a unique
       | way of doing it but that's pretty doubtful. In general this field
       | is getting close to large scale use in humans as it is.
       | 
       | Oddly, there's already a different Australian startup from
       | another university doing extremely this.
       | https://www.imcrc.org/blt-allegra/
        
         | twic wrote:
         | Lo and behold, the patent [1] says:
         | 
         | > [0038] In preparing the xenograft for use, the tendon is
         | surgically dissected and removed from the paratenon (tendon
         | sheath). The tendon is composed mostly of an extra-cellular
         | collagen matrix, which is non-immunogenic. The tendon may
         | therefore require no denaturing (decellularisation) prior to
         | implantation into a mammal. In some embodiments, the tendon may
         | be subjected to a decellularisation process prior to
         | implantation. In removing the cells from the tendon, the
         | immunogenic antibodies within the cells are also removed, thus
         | rendering the tendon non- immunogenic. Methods of
         | decellularisation of tendon tissue are known in the art. Such
         | methods include physical, chemical and enzymatic treatments,
         | wherein the cells within the tendon are lysed, leaving an
         | undamaged extracellular matrix having the same physical and
         | biochemical properties as the natural tissue.
         | 
         | So it is decellularisation, they aren't claiming any particular
         | decellularisation method, but it's quite possible they have
         | some particular recipe for decellularisation which works well,
         | and which they are keeping secret.
         | 
         | [1]
         | https://patents.google.com/patent/WO2019014698A1/en?oq=20179...
        
       | moomoo11 wrote:
       | Cool but I'd rather have fully automated robotic legs that can
       | let me jump like 30ft and sustain falls from 100+ ft.
        
       | a_shovel wrote:
       | <joke>I wonder, does this also make knees harder and
       | faster?</joke>
        
         | a_shovel wrote:
         | Tough crowd.
        
           | Qwertious wrote:
           | The downvotes are probably due to the XML.
        
       | omnicognate wrote:
       | Kangaroo knees? Where do I sign up?
       | 
       | And if you could replace my spine too while you're at it, that'd
       | be great.
        
         | [deleted]
        
       | dvh wrote:
       | Doesn't this increase the chance of novel diseases when they
       | cross from kangaroo to human?
        
         | cududa wrote:
         | The ligament is denatured/ all cells removed which just leaves
         | a scaffolding for the natural tendon to populate
        
       | danw1979 wrote:
       | If they're using decellularization to prevent rejection, does the
       | tissue have to be ... freshly harvested (i.e. in a medical
       | setting) ?
       | 
       | Or would the offcuts from abattoir-killed roos be of sufficient
       | quality ?
        
         | orwin wrote:
         | It seems tu be sufficient. Although maybe the abattoir have to
         | really follow sanitary rules for once, that'll cut into the
         | profits.
        
       | twic wrote:
       | > They have also developed a way of ensuring the kangaroo
       | xenografts are not rejected after transplant. The key to this is
       | what he describes as "the special sauce", and it is a closely
       | guarded secret that has already been patented.
       | 
       | PATENTS DO NOT WORK THAT WAY!
       | 
       | Anyway this appears to be it:
       | 
       | https://patents.google.com/patent/WO2019014698A1/en?oq=20179...
        
         | jaggederest wrote:
         | I love it when people do this "patented secret" thing. Patents
         | are public for very good reason - society protects ideas that
         | are documented publicly so that the public knowledge is
         | improved after the patent expires.
        
           | twic wrote:
           | Although there are secret patents:
           | https://slate.com/technology/2018/05/the-thousands-of-
           | secret...
        
             | taneq wrote:
             | Like most (all?) governments the U.S. government has a
             | strict set of rules that it must follow unless it decides
             | it doesn't want to.
        
               | deaddodo wrote:
               | Well sure. Because if the US govt's patent on hypersonic
               | rocket propulsion (as a conjectural example) were public
               | knowledge, it would be trivially simple for their rivals
               | to use that information in their own programs or
               | countermeasures.
               | 
               | Surely it's evident that most nations would find an
               | imperative in keeping that knowledge guarded?
               | 
               | The govt doesn't _have_ to patent these techniques at
               | all. They do so for the benefit of public enterprises (so
               | contractors and military industry can benefit) and so
               | that the knowledge _does_ eventually enter the public
               | commercial sphere. That article itself mentions multiple
               | patents that eventually had the veil lifted and /or
               | expired.
        
               | Dylan16807 wrote:
               | How do contractors benefit from the patent?
               | 
               | They can "eventually" release the information whether or
               | not they had a secret patent.
        
               | red-iron-pine wrote:
               | they "benefit" by agreeing to play ball getting the
               | (often absurdly huge) defense contract.
               | 
               | and since the contractors are taking federal money, the
               | gub'mnt reserves the rights to any of their findings;
               | agree or don't get the contract.
               | 
               | but this then gives the Gov another angle if the
               | contractor deliberately or accidently releases or sells
               | those secrets -- not just distributing classified
               | materials, but also patent violations, and potential
               | lawsuits. it's a tool to ensure compliance if/when the
               | government is funding stuff they don't want released
        
               | sparrowInHand wrote:
               | And who watches the watchmakers?
        
         | aidenn0 wrote:
         | Furthermore the patent states that "Methods of
         | decellularisation of tendon tissue are known in the art." which
         | means he either lied in the patent, or it's not "special sauce"
        
           | DebtDeflation wrote:
           | I mean, it starts out by saying that the special sauce
           | usually isn't even needed.
        
         | benatkin wrote:
         | Another case of this:
         | 
         | > You've heard of the golden rule, haven't you? Whoever has the
         | gold makes the rules.
        
         | arijun wrote:
         | Ah, yes, ahem, I definitely understood exactly what that patent
         | is saying, but perhaps you could summarize it for all the other
         | people who can't parse a patent immediately?
        
           | jaggederest wrote:
           | It basically confirms the theory discussed in this thread:
           | 
           | https://news.ycombinator.com/item?id=36785816
           | 
           | In layman's terms, they're using achilles or tail tendon from
           | certain kangaroo species that have been carefully dissected
           | to retain only non-immune-reactive tissue (or
           | decellularized), and sticking it in people's knees and other
           | ligament sites in the body because it's strong.
        
           | deaddodo wrote:
           | Which part is difficult to understand? They use medical and
           | scientific terminology, but otherwise it's pretty
           | straightforward.
           | 
           | It essentially covers the usage of macropod (kangaroo,
           | specifically, of an enumerated variety) tendon and ligaments
           | in a grafting procedure using "undisclosed" materials for
           | compatibility. It then enumerates specific elasticity
           | parameters before giving a description of the problem
           | (background).
           | 
           | Basically, exactly what the topic article summarizes into
           | layman.
        
         | ckemere wrote:
         | Ironically, the whole patent appears to be about the concept
         | (how is that patentable?!). The actual treatment is "known in
         | the art ".
         | 
         | Quote: "The tendon is composed mostly of an extra-cellular
         | collagen matrix, which is non-immunogenic. The tendon may
         | therefore require no denaturing (decellularisation) prior to
         | implantation into a mammal. In some embodiments, the tendon may
         | be subjected to a decellularisation process prior to
         | implantation. In removing the cells from the tendon, the
         | immunogenic antibodies within the cells are also removed, thus
         | rendering the tendon non- immunogenic. Methods of
         | decellularisation of tendon tissue are known in the art. Such
         | methods include..."
        
         | AYBABTME wrote:
         | Seems like the special sauce is nothing at all but what seems
         | to be well known prior art:                   [0038] In
         | preparing the xenograft for use, the tendon is surgically
         | dissected and removed from the paratenon (tendon sheath). The
         | tendon is          composed mostly of an extra-cellular
         | collagen matrix, which is non-         immunogenic. The tendon
         | may therefore require no denaturing
         | (decellularisation) prior to implantation into a mammal. In
         | some          embodiments, the tendon may be subjected to a
         | decellularisation process          prior to implantation. In
         | removing the cells from the tendon, the          immunogenic
         | antibodies within the cells are also removed, thus rendering
         | the          tendon non- immunogenic. Methods of
         | decellularisation of tendon tissue are          known in the
         | art. Such methods include physical, chemical and enzymatic
         | treatments, wherein the cells within the tendon are lysed,
         | leaving an          undamaged extracellular matrix having the
         | same physical and biochemical          properties as the
         | natural tissue.
        
           | koheripbal wrote:
           | This was tried with pig tendons about 20 years ago.
           | 
           | I wonder what has changed.
        
         | rcxdude wrote:
         | Patents can in fact work that way in practice. Generally
         | speaking the art of the patent is to describe the technique in
         | as broad a way as possible as to cover any possible way to
         | accomplish anything similar while avoiding as many important
         | details needed to actually accomplish the goal as possible.
         | That way the patent is useless for anyone who wants to solve
         | the problem but very useful for you to go after anyone who
         | manages to figure it out on their own.
        
           | toss1 wrote:
           | That is indeed the current practice, but it is the opposite
           | of the original intent of patent concept. The idea was to
           | grant a temporary monopoly in exchange to revealing the
           | technique -- it was supposed to advance technology faster.
           | 
           | The standard was (and AFAIK, still is) that the technique or
           | technology must be revealed in sufficient detail that it can
           | be reproduced "by a skilled practitioner in the field without
           | undue experimentation".
           | 
           | Of course, that was at a time when technological progress was
           | much slower, and less transnational.
        
             | rcxdude wrote:
             | yeah, there's a pretty wide gulf between patents in
             | practice and their original intent, alas.
        
       | dylan604 wrote:
       | Just in time for the WWC where there's recent news articles about
       | why the women's game has so many ACL type injuries.
        
       | pluijzer wrote:
       | As someone with trouble giving up on meat this is a highly
       | hypocritical comment but news like this always gives me an
       | unsettling feeling in my stomach. We are sacrificing the life of
       | an intelligent entity to fix the knee of another. Like I said it
       | is hypocritical and I probably found a way to explain it away if
       | I needed itvmyself and am happy for the people it will help but
       | still, we as a species do have the tendency to put ourselves
       | above others. I feel very conflicited by it.
        
         | mensetmanusman wrote:
         | It's possibly the Disney effect on the culture affecting your
         | subconscious.
         | 
         | If we had happy cows as cartoon characters we might not eat as
         | much beef.
        
         | xgl5k wrote:
         | I am not conflicted in the slightest. It's a "dog eat dog"
         | world where every species put's its survival over others.
         | 
         | I hunt and slaughter animals. While I do fully understand and
         | appreciate the sanctity of all forms of life, I also understand
         | that my actions are part of the natural order of the universe.
        
         | ceejayoz wrote:
         | I'd draw a pretty big distinction between this and regular meat
         | eating; you're not getting a new tendon several times a week.
         | 
         | In this case, it's not even extra animal deaths:
         | 
         | > It was important to Dr Hartnell that no kangaroos were killed
         | expressly for his research, and this has remained his practice
         | throughout his investigations: all of the work has been done
         | only using kangaroos that have either been culled for reasons
         | of population control or harvested for meat.
        
           | foobarian wrote:
           | TIL kangaroos are harvested for meat
        
             | microtherion wrote:
             | If you're in the US, meat selection tends toward the
             | conservative. People have literally been fired for serving
             | kangaroo: https://time.com/5430454/nebraska-school-cook-
             | fired-kangaroo...
             | 
             | But in some European countries, more bits of the animal are
             | being eaten (beef tongue, e.g.), and more animals are being
             | eaten (e.g. horses). In Switzerland, kangaroo and ostrich
             | became somewhat popular when at the height of the Mad Cow
             | Disease epidemic, people were reluctant to eat beef.
        
             | reaperman wrote:
             | Leather as well - kangaroo leather was rather prized in the
             | motorcycle community for being more abrasion-resistant per
             | thickness/weight than cow-hide leather. I think its
             | popularity has somewhat fallen off but I believe it's still
             | the most performant material.
        
               | abracadaniel wrote:
               | Same for whips as I recall. Niche use cases, but it's
               | apparently much better than others.
        
             | tsol wrote:
             | You can buy the jerky on Amazon last I checked. This amazed
             | me the first time I learned about it but apparently it's
             | pretty mundane in Australia
        
             | ceejayoz wrote:
             | Yeah. Very similar to venison, in both taste (lean and a
             | bit gamey) and reasons for culling; too many in an area and
             | no real predators other than humans.
        
               | aziaziazi wrote:
               | That sounds ironic as kangaroo's predators were predated
               | ("culled") by humans.
        
               | callalex wrote:
               | Same with deer (wolf culling)
        
               | 9991 wrote:
               | We're just going to work our way down the food chain.
        
               | pfannkuchen wrote:
               | Already have, many people personally cull grass
               | periodically.
        
               | ambicapter wrote:
               | Out of curiosity, what are/were kangaroo's predators?
        
               | ceejayoz wrote:
               | https://en.wikipedia.org/wiki/Thylacoleo
               | 
               | https://en.wikipedia.org/wiki/Thylacine too, but probably
               | not for adult kangaroos.
        
               | aziaziazi wrote:
               | Also dingos, crocodiles, pitons and eagles.
        
               | Qwertious wrote:
               | Also australian aborigines.
        
             | pdabbadabba wrote:
             | It's a common ingredient in dog food. If a dog is having
             | some sort of allergic reaction, a vet will often recommend
             | switching to kangaroo food to try to rule out a dietary
             | cause. (I guess because kangaroo allergies are rare in
             | dogs? At least in NA?).
        
               | nineteen999 wrote:
               | It's a common ingredient in human food here in Australia.
               | 
               | https://www.coles.com.au/search?q=kangaroo
               | 
               | It's pretty gamey, I don't find it unpleasant, but I
               | wouldn't eat it in favour of a good beef steak.
        
             | senectus1 wrote:
             | not just, but yeah !
             | 
             | Kangaroo meat is super lean and very tasty. needs to be
             | cooked very carefully or it goes very chewy and dry.
        
           | aziaziazi wrote:
           | Thanks for pointing that quote up. Nonetheless I have the
           | feeling it only respond to GP in a very short-sighted term. I
           | do understand medical research should go on but don't
           | mismatch research process with industrial application,
           | especially when they bring ethical concerns.
        
           | pluijzer wrote:
           | That is true, I think I agree with this.
        
         | dehrmann wrote:
         | NSW is culling them because of overpopulation. At least that's
         | what the kangaroo scrotum keychain the gift shop was selling
         | said.
        
         | 542354234235 wrote:
         | >we as a species do have the tendency to put ourselves above
         | others
         | 
         | I mean, all species do this. Antelope don't lay down to be
         | eaten by lions because it is good for the lion.
         | 
         | It is funny that you feel like this is wrong while eating meat.
         | I also eat meat and I would say it is morally much worse to
         | kill a pig because I like the taste of the food and killing a
         | kangaroo to provide significant quality of life improvement
         | through increased mobility to those with severely damaged
         | knees. I have zero issue with this being used until a better
         | solution without killing a kangaroo could be developed.
        
         | Tade0 wrote:
         | I suppose this sort of grafting is a behaviour unseen in the
         | natural world, whereas eating is.
         | 
         | I admit my first thought was "are they going to at least eat
         | the kangaroo?" - like that's any consolation for the animal.
        
           | SoftTalker wrote:
           | Almost all of medicine (aside from the few natural/herbal
           | remedies that actually work) is unseen in the natural world,
           | I don't think we justify closing all the hospitals and
           | medical clinics on that basis.
        
         | xutopia wrote:
         | I understand that paradox. The way I rationalize when it comes
         | to food is that we wouldn't feel bad for a lion eating a
         | gazelle... well we might but it would be required as lions eat
         | that food. We're somewhere on that spectrum of omnivores who
         | eat meat and that means eating animals.
        
           | hombre_fatal wrote:
           | > we wouldn't feel bad for a lion eating a gazelle
           | 
           | Most people probably do feel bad. Presumably you'd also feel
           | bad if a lion attacked and ate a human even though it was
           | just doing what you purport to be "required".
           | 
           | Where it goes south is when people cherry pick the behavior
           | of animals to justify their own actions.
        
             | xutopia wrote:
             | Say you're driving down the road and get into an accident.
             | A choice in front of you is that you either hit a squirrel
             | or a child.
             | 
             | Would you feel better or worse?
        
           | ceejayoz wrote:
           | The lion doesn't really have our capacity to reason (to the
           | same extent) or come up with alternatives. Lions can't make
           | an Impossible Burger; we can, which changes the ethical
           | calculus a bit.
        
             | reformedveget wrote:
             | That's because the lion doesn't have an abundance of
             | resources that allow it care about "ethical calculus." It
             | simply eats, mates, socializes, and sleeps; and it is
             | satisfied with this arrangement -- never feeling the need
             | for "more."
             | 
             | In my opinion, thought that verges beyond: "how to acquire
             | food," "how to acquire mate," "how to acquire friend," and
             | "how to acquire sleep" is "too much," and a neuroses. Or
             | maybe all of our actions are predicated on fulfilling these
             | base needs? And that our civilization has created an
             | environment where these needs can no longer be simply
             | attained, so we come up with ever more complex ways to
             | attempt attaining them.
             | 
             | One can also make the distinction that those needs are also
             | simply just "feel good" and "don't feel bad." For a lion,
             | the aforementioned things are enough to "feel good." But
             | for us people, the simple pleasures have become
             | unattainable in any sustainable sense. So we once again try
             | to find something to make us feel good. For the GP, that
             | might be practicing vegetarianism; for the readers of
             | Hacker News, it might be stuffing their minds full of
             | information of only temporary utility.
             | 
             | And for what? So we can feel good, and escape the bad.
             | "Ethical calculus" is no different. It's simply a
             | rationalization of our base needs. Though I wish the
             | simpler pleasures were more readily available... I'm
             | getting awfully tired of working harder and smarter to find
             | outlets!
        
           | inkcapmushroom wrote:
           | Chimps kill and eat monkeys and even other chimps. Not sure
           | what I should rationalize through that behavior.
        
         | go_prodev wrote:
         | If it helps to put your mind at ease, in some parts of
         | Australia Kangaroos are a pest. They are culled in agricultural
         | areas and this treatment prevents some of the animal from going
         | to waste. They're also often roadkill as they chase headlights
         | at night.
         | 
         | Companies pay hunters around $1-$2 per kg for the kangaroo
         | meat. An adult kangaroo can be upwards of 60kg (130lb). The
         | meat is often used for dog food, but is extremely lean but a
         | bit gamey tasting I've been told.
         | 
         | So, hopefully this treatment doesn't cause additional death of
         | the roos, but helps to make their deaths less wasteful.
        
         | JamesBarney wrote:
         | I don't I always find it crazy that society has drawn these
         | weird lines where if you want some chicken tenders you can
         | slaughter a billion and treat them terrible but if you want to
         | push the limits of human knowledge you need 6 levels of
         | oversight.
        
           | hombre_fatal wrote:
           | It's a phenomenal demonstration of the human brain when a
           | video of a guy being mean to a dog will win the outrage of
           | Twitter while 23,000,000+ land animals are slaughtered per
           | day for food in the US.
           | 
           | What we seem to care about as a civilization is like a
           | narrowly focused laser: we can only wrap our heads around the
           | things small enough to fit in the tiny spotlight. Anything
           | bigger and we just kinda take it for granted.
        
             | OkayPhysicist wrote:
             | It's not that weird. We bred dogs for millennia to read and
             | express human-recognizable emotional responses. They are
             | sympathetic by design. In contrast, We bred most everything
             | else to be delicious. A more fun one is to look at people's
             | responses to guinea pigs, which were bred for eating but
             | now are seen as pets.
        
               | hombre_fatal wrote:
               | That may be a satisfying explanation at first pass, but
               | it breaks down quickly under scrutiny, I think.
               | 
               | We can recognize the emotional state of pigs and cows,
               | probably more than even we can with cats. Certainly more
               | than we can with rodents and other pets.
               | 
               | I also think most people wouldn't accept a video of
               | someone abusing a cow, pig, or even a chicken. Let's just
               | replace dog with piglet in my comment if that helps track
               | the point.
               | 
               | I'd wager most people wouldn't find footage inside a
               | slaughterhouse or factory farm very palatable. But this
               | happens by the hundreds of millions daily.
        
               | OkayPhysicist wrote:
               | Cats may not emote in human terms as well as dogs, but
               | they are unusually good among the animal kingdom at
               | reading human emotional expression.
        
         | DashAnimal wrote:
         | I really encourage you to try and give up meat and eggs again!
         | It's not too hard -- just like any other habit to build and
         | continue. And honestly I have the same mindset as you. The
         | sacrifice we make to intelligent creatures for 5 minutes of
         | sensory pleasure (taste/smell) makes no sense.
        
           | stuff4ben wrote:
           | But they're sooooo tasty! Other animals kill other animals,
           | humans are no different.
        
             | balloonthief wrote:
             | Other animals also commit rape for pleasure, but we don't
             | use that as a moral guideline for human behavior.
        
             | legulere wrote:
             | Other animals also practice cannibalism and so do humans.
             | Killing other animals for food is not the same as killing
             | humans, but also we humans differ from other carnivores and
             | omnivores.
             | 
             | I find meat also very tasty and eat meat. There are several
             | ways to reduce impacts though: Eating less will most likely
             | also have a health benefit. Game doesn't suffer it's whole
             | life but only when it gets hunted.
        
             | spicymaki wrote:
             | Sure I think there is broad agreement with taste argument.
             | However, I think we can agree that humans are on another
             | scale with respect to animal killing. We are way past the
             | survival of the fittest on the plains of the Serengeti
             | here.
        
               | ChatGTP wrote:
               | We might be, but that's not by choice for many.
               | 
               | I _hate_ factory farming and if we lived in a world with
               | more wilderness and healthier oceans, I think hunting is
               | a fairly humane to operate. For most wild animals they
               | die horrible deaths, the most humane way to go is being
               | taken by an expert marksman or archer during adulthood.
               | 
               | I've seen a fish have it's face mauled off by squid, and
               | much worse. If that fish could've been dispatched by fish
               | spike in seconds as opposed to having it's face mauled
               | off, I think it would've went with the spike.
        
               | flextheruler wrote:
               | What would you say to someone who's only qualm is the
               | animals humane treatment?
               | 
               | I typically only eat chicken but I just don't see an
               | issue with if the chickens are humanely treated and
               | killed. What else would we do with all the chickens
               | besides eat them? They'd die out if we stopped eating
               | them and it's not like anyone's going to put them in a
               | zoo.
               | 
               | The way I see it is we've bred these animals as livestock
               | and we're responsible for them as livestock and that's
               | okay. It's how we treat them as livestock that matters.
               | Factory farms are one of many gross byproducts of
               | industrialization that we now have to deal with like
               | fossil fuels.
        
               | ceejayoz wrote:
               | > They'd die out if we stopped eating them and it's not
               | like anyone's going to put them in a zoo.
               | 
               | There are feral chickens in quite a few places.
               | https://en.wikipedia.org/wiki/Feral_chicken
               | 
               | Tahiti's airport has a bunch of them.
        
               | SoftTalker wrote:
               | I'm not sure I agree that a feral chicken has a better
               | life than a domestic chicken being humanely raised for
               | meat/eggs. The feral chicken probably lives in a state of
               | borderline starvation and is at risk from disease and
               | predators; the domestic chicken gets to walk around in a
               | protected area and has a good supply of nutritious food
               | and water and a place to get inside at night and when the
               | weather is bad.
               | 
               | Sure the big factory chicken farms are something else,
               | but you can buy ethically sourced chickens (or raise them
               | yourself if you have the space) if that bothers you.
        
               | ceejayoz wrote:
               | I mean, we're getting into Star Trek episode
               | ethical/moral dilemmas; is it better to live in a gilded
               | cage, or be free but at risk of poverty? No right answer
               | to this.
        
               | hombre_fatal wrote:
               | Well, the decision isn't between having feral chickens
               | vs. caging them.
               | 
               | Domesticated chickens are bred into existence. We could
               | just stop doing that if we had ethical problems with it.
               | The consideration doesn't hinge on whether there exists
               | some wild variant of the animal we're breeding.
        
               | ceejayoz wrote:
               | My note about feral chickens was to contest the stated
               | idea upthread that the species would die out if we
               | stopped intentionally breeding them.
        
               | hombre_fatal wrote:
               | True, my comment was really for them: What's wrong with
               | stopping the breeding of a species, especially one we
               | bred to exploit.
        
               | digging wrote:
               | > I typically only eat chicken but I just don't see an
               | issue with if the chickens are humanely treated and
               | killed.
               | 
               | If that's your only concern, and not environmental
               | destruction, then that's fine - if you're ensuring that
               | the chickens you eat are humanely treated and humanely
               | killed. The best way to do that is to buy from local
               | farms you can visit - otherwise it's just aspirational
               | and in effect identical to someone who doesn't care at
               | all.
               | 
               | > The way I see it is we've bred these animals as
               | livestock and we're responsible for them as livestock and
               | that's okay.
               | 
               | But we can stop mass producing them. There don't need to
               | be 30 billion of them. Scale is what makes factory
               | farming such a catastrophe (environmentally, ethically,
               | and for our own health).
        
               | hombre_fatal wrote:
               | > What would you say to someone who's only qualm is the
               | animals humane treatment?
               | 
               | The typical response to this would be a game of Name The
               | Trait.
               | 
               | For example, what would be wrong about farming humans as
               | long as we treat them humanely?
               | 
               | Or more generally, what's true of animals that if made
               | true of humans would make it okay to farm humans? And
               | then when you come up with a symmetry breaker, we apply
               | it to humans and see if you're okay with the reductio. If
               | so, you bite the bullet on a crazy human atrocity, and if
               | not, then it's not the trait that actually matters to
               | you.
        
               | somenameforme wrote:
               | There's a philosophical problem you run into here. A man
               | who has no hair is obviously bald, and so is a man with
               | exactly 1 hair. But how many hairs does it take for this
               | man to suddenly no longer be bald? Not only is there no
               | "real" answer; the practical answers will vary in
               | subjective and inconsistent ways from person to person.
               | It's an abstract and largely subjective value judgement.
               | And I think the same is true here. There's no single
               | binary value where something goes from A to B.
               | 
               | Take mosquitoes. Even in areas where mosquitoes rarely if
               | ever carry diseases, people are perfectly cool with
               | widescale genocide. Why? Because half of those animals
               | can, on occasion, give us a little itchy that's mildly
               | inconvenient for a few moments. Roaches are another
               | example. In their case, their life itself is often worth
               | less than our mild annoyance or discomfort at seeing
               | them. And so on. In practice, most people are perfectly
               | fine with killing the overwhelming majority of species of
               | animals.
               | 
               | And so too here. I simply do not see any problem with
               | killing a e.g. chicken for food. Oddly enough I have a
               | _strong_ suspicion that the more one is around animals,
               | the more this becomes true. Which is paradoxical, because
               | contrary to what you might think, even chickens can be
               | awesome little affectionate critters. It 's probably
               | because you see the cycle of life itself more regularly.
               | Foxes are cute, clever, and awesome critters - until one
               | makes its way into your chicken coop, kills every hen,
               | and takes exactly 1 away. At the same time, that's just
               | the nature of life. It's all as natural and normal as the
               | fact that you and I too will be wormfood soon enough.
        
               | OkayPhysicist wrote:
               | That's trivially solved with shared culture. Simply by
               | both being human, we share a level of shared experience
               | that would make me uncomfortable eating you. To a lesser
               | extent, we have a shared experience with our domesticated
               | pets, which is why we find it repugnant to eat them, but
               | unlike with Grandma it's okay to give them the Old
               | Yeller' treatment when need be.
               | 
               | Most edge cases you could come up with are covered by "it
               | wouldn't necessarily be unethical to eat them, but we
               | have a universal taboo because edge cases are so absurd
               | and rare."
        
               | hombre_fatal wrote:
               | You're putting forth multiple traits, btw, but I don't
               | think it's as trivial as you think it is.
               | 
               | One trait seems to be "shared culture" whatever that
               | means. What about humans with cultures we don't share?
               | What about humans with downright alien cultures we can
               | hardly understand nor agree with? What does "shared
               | experience" with a dog mean? What about brain-dead humans
               | that we don't share an experience with?
               | 
               | Another trait seems to be "being a human". What about
               | Santa's elves or any hypothetical sentient being that's
               | not a human? Does any alien race that discovers us have
               | the ethical justification to farm us?
               | 
               | > it wouldn't necessarily be unethical to eat them, but
               | we have a universal taboo because edge cases are so
               | absurd and rare.
               | 
               | Would it be okay to farm or enslave humans if we simply
               | didn't have that taboo? Or in a hypothetical world where
               | it wasn't taboo: would it be okay then?
               | 
               | These aren't edge cases btw, these are reductios that
               | test for position's consistency and dispel the sort of
               | "I'll know it when I see it" hand-waving we like to do.
               | 
               | Any coherent position has a coherent answer to
               | hypotheticals.
               | 
               | There is a trivial answer that does nip it easily in the
               | bud: we agree to value sentience thus we stop farming
               | sentient beings whether they're human, cows, or Santa's
               | elves.
               | 
               | Finally, I was just offering a potential response to your
               | question. HN is a poor place for this kind of discussion,
               | but I hope you at least see that there is conversational
               | meat on the bone, pun not intended.
        
               | OkayPhysicist wrote:
               | The less "like us" they are, they more justified we are
               | in killing them. "Like us" is tied around shared culture
               | and experience. If you asked me to choose between saving
               | the life of an elf and the life of a human being, I'd
               | choose the human damn near every time (barring cases
               | where the human deserves death regardless of the
               | dilemma).
               | 
               | "Shared experience" in this case is a basic history of
               | doing stuff together, or in a sympathetically similar
               | way. Dogs have been shaped to serve side-by-side with
               | humans as companions, sharing in our experiences. So
               | eating them is wrong. There are no humans that are less
               | like us than than the animals we eat. Brain-dead humans
               | are an example of just following taboo: We don't kill and
               | eat other humans, because of the whole "we are more alike
               | than we are different" thing, and incidentally extend the
               | same courtesy to things that take complex explanations
               | for not being us.
               | 
               | If we ran into other conscious, sapient species, we'd
               | probably be hesitant about killing them due to the shared
               | experience of sentience making them a lot more like us
               | than a cow. But on the other hand, killing an alien would
               | be a hell of a lot more permissible than killing a human.
               | 
               | And I apply the same kind of logic to people. My friends
               | and family are significantly more valuable than random
               | strangers. In a trolley scenario with one of my friends
               | on one track and 3 strangers on another, I'd save my
               | friend, every time, and I wouldn't trust anybody who
               | would answer otherwise.
        
             | psychlops wrote:
             | Using animal behavior as a blueprint to justify human
             | behavior won't end well.
        
           | SoftTalker wrote:
           | It's possible to get adequate nutrition with a vegan diet but
           | it's a lot of effort (at least until it becomes habit) and
           | for children it's particularly risky. People are omnivores
           | and meat provides a lot of the nutrition we need. I don't
           | think anyone should feel guilty about eating meat per-se,
           | though the conditions and treatment of animals in some
           | farming operations are valid concerns.
        
             | civilitty wrote:
             | _> the conditions and treatment of animals in some farming
             | operations are valid concerns_
             | 
             | Anyone who has the room for a chest freezer in their garage
             | and can afford it can go to a local farm and buy a whole
             | (or half or quarter) cow, lamb, or pig and have them
             | slaughtered and deep frozen.
             | 
             | Depending on their locality, there are usually plenty of
             | such farms that usually treat their animals much better
             | than the farms supplying super markets. Makes it much
             | easier to inspect their farm in person too.
        
         | slashdev wrote:
         | Kangaroos don't have many natural predators anymore. Even if
         | you don't harvest them for meat, you'd have to cull them to
         | prevent them overpopulating and destroying their environment.
         | 
         | The article mentions that the kangaroos harvested for meat are
         | sufficient to meet the current worldwide needs for ACL
         | surgeries.
         | 
         | Sometimes killing animals is the ethical thing to do. Reality
         | is complex.
        
           | dehrmann wrote:
           | What makes the kangaroo problem even worse is they're
           | grazers, and maybe it's just a former British colony thing,
           | but people like to plant grass.
        
           | cyrnel wrote:
           | > you'd have to cull them to prevent them overpopulating and
           | destroying their environment.
           | 
           | We don't do this for cats, why should we have to do it for
           | kangaroos? Trap Neuter Release exists. There have been
           | struggles with implementing it, but it seems largely to do
           | with lack of awareness and funding.
        
             | slashdev wrote:
             | Cats are predators, that's very different from say deer or
             | kangaroo populations, which tend to overboom and then
             | starve after they strip the environment of the plants they
             | eat.
        
             | HeyLaughingBoy wrote:
             | AFAICT, no one around here culls or traps cats, but we
             | don't have a cat overpopulation problem. OTOH, even with
             | hunting seasons, we definitely have a deer population
             | problem, and the rabbits have been going _insane_ this year
             | for some reason.
             | 
             | Perhaps it's just a case of different strategies for
             | different regions.
        
               | bpiche wrote:
               | New Zealand apparently does. Never been there, seems
               | lovely
               | 
               | (edit: this opening graf is too good not to share)
               | 
               | "Animal welfare protestors at a hunting contest in rural
               | New Zealand have faced off against a group of child
               | attendees, some clutching dead feral cats, who repeatedly
               | chanted the word "meat" at demonstrators."
               | 
               | https://www.theguardian.com/world/2023/jun/28/chaos-at-
               | new-z...
        
         | 1MachineElf wrote:
         | A film that explores a similar theme is The Island (2005) -
         | recommended!
        
       | mensetmanusman wrote:
       | How would this not result in kangaroo harvesting
       | farms/extinction?
        
         | jb12 wrote:
         | hahaha if you can figure out how to farm Kangaroos, let us
         | Aussies know please!
        
       | at_a_remove wrote:
       | I gather that kangaroo "leather" is also quite resilient.
        
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