[HN Gopher] Scientists need to get high
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       Scientists need to get high
        
       Author : thx-2718
       Score  : 67 points
       Date   : 2023-06-01 14:55 UTC (8 hours ago)
        
 (HTM) web link (nautil.us)
 (TXT) w3m dump (nautil.us)
        
       | outside1234 wrote:
       | Sounds like rationalization for the next Fentanyl outbreak
        
         | coffeebeqn wrote:
         | Psychedelics aren't addictive and most you can not take
         | multiple days in a row
        
       | canadiantim wrote:
       | We need a better science for sharing experiences. Science is
       | great for sharing experiments where we can replicate the
       | conditions in the outside world. But it's terrible for sharing
       | experiences because they are harder to share in a replicable way,
       | yet that's where some of the most important insights are.
        
         | nine_k wrote:
         | Experiences can be hard / impossible to share in principle:
         | https://en.wikipedia.org/wiki/Qualia
         | 
         | Humans do need a better language to describe certain areas of
         | experience though, states of mind and emotions. Poetic language
         | is a good approximation, but it uses various quirks and
         | undocumented properties of the "normal" language to get its
         | point across. It's a poor fit even for philosophy, to say
         | nothing of scientific research.
        
       | DueDilligence wrote:
       | [dead]
        
       | jacooper wrote:
       | [flagged]
        
         | capableweb wrote:
         | In order to facilitate some sort of discussion rather than
         | knee-jerk reactions, why not?
        
       | NickC25 wrote:
       | All for it.
       | 
       | LSD and other similar substances can offer an incredible insight
       | to people who are equipped to handle it. Such substances create
       | new pathways in your brain and increase neuroplasticity.
       | 
       | It's not the one-stop solution to everyone's problems and should
       | NOT be treated as such (far from it!), but it does offer
       | tremendous perspective and insight to those who know what they're
       | getting into.
        
         | vorpalhex wrote:
         | One of the issues is that LSD also simulates the feeling of
         | insight. How many trip reports mention "finding the solution to
         | everyone's problems" and "forgetting" it upon sobering? (They
         | didn't forget, they never had it, the LSD simulated having
         | it...)
         | 
         | Maybe it's a better cultural value for our truth seeking groups
         | to avoid psychedelics and other hallucinogens.
        
           | ethanbond wrote:
           | I've never read any trip report including a claim like that.
           | 
           | Lots of people claim to have solved a problem _they_ have,
           | and some of these solutions end up being forgotten, bad, or
           | authentically and positively life-changing.
           | 
           | Hard to draw conclusions from this landscape (which is why
           | scientists should be experimenting with them).
        
           | joenot443 wrote:
           | In my experience, the "simulated insight" (and I agree, that
           | is roughly what I'd call it) ends up being something more
           | attune to "I need to take better care of my apartment" or
           | "Revolver truly is their best album" or more recently, "I
           | need to learn to write shaders." The insights one experiences
           | are personal, whether or not they're actually beneficial to
           | the waking self.
           | 
           | I haven't met anyone who's seriously felt they'd "discovered"
           | or solved anything serious while tripping. I know people
           | who've left relationships or changed career paths, so as with
           | nearly anything psychoactive, YMMV.
        
           | chaps wrote:
           | Have you ever done psychedelics?
        
             | nathan_compton wrote:
             | I've done psychedelics of many types and I find the so-
             | called "insights" they offer to be banal in the extreme.
        
               | chaps wrote:
               | Not exactly going to disagree with you there. Just felt
               | it was an important question to ask considering the
               | rigidity of their comment.
        
               | nathan_compton wrote:
               | I'm not the original reply, by the way. I think
               | psychedelics can be fun and extremely
               | liberating/relaxing. But they have not given me any
               | significant personal, scientific, literary or other
               | insights.
        
               | grugagag wrote:
               | I find that whatever insights, they're personal. But
               | their general effect humbling our egos. I find that to be
               | of great use in a selfish narcissistic society we're
               | living in. I remember after having an LSD trip with good
               | personal insights I got home and had cathartic session of
               | sobbing. It felt absolutely great to do something I
               | rarely do. Last time I did this was more than 15 years
               | ago and feel that I'm still drawing some essence from
               | this experience. Perhaps if I find myself stuck or at
               | crossroads I'll give it another go.
        
           | galleywest200 wrote:
           | I am not sure if LSD use in college gave me any real
           | insights, but it did leave me with a permanent recognition of
           | my internal thought processes. Becoming acutely aware of them
           | essentially. Instead of two layers (internal thoughts then
           | observed reality) there were three (myself, internal
           | thoughts, then observed reality).
        
             | rainclouds wrote:
             | Spot on. My ability to separate myself from an issue and
             | view it as a 3rd party came around this.
             | 
             | Sometimes you had separate yourself pretty far from
             | something to be able absorb and understand an issue, and
             | LSD can cause that space.
             | 
             | I see the space, the separating, as the benefit. Gave new
             | prospective.
        
           | pengaru wrote:
           | > One of the issues is that LSD also simulates the feeling of
           | insight. How many trip reports mention "finding the solution
           | to everyone's problems" and "forgetting" it upon sobering?
           | (They didn't forget, they never had it, the LSD simulated
           | having it...)
           | 
           | Are you sure you're not confusing LSD with THC? What you're
           | describing is well known as "stoner epiphanies"...
        
           | _a_a_a_ wrote:
           | Pls post (say) 3 examples of <<"finding the solution to
           | everyone's problems" and "forgetting" it upon sobering?>>
           | 
           | I'm only aware of it happening a NOx trip in the 1800's
           | 
           | > Maybe it's a better cultural value for our truth seeking
           | groups to avoid psychedelics and other hallucinogens
           | 
           | So. You're afraid of them then. Otherwise you'd post some
           | actual evidence.
        
           | [deleted]
        
           | NickC25 wrote:
           | It's important to have an experienced tripper with you so
           | that when you have a solution, someone can write it down if
           | you're unable to. Or a voice reorder, or some way of
           | capturing your insight.
           | 
           | Has worked every time for me.
        
         | bitlax wrote:
         | [flagged]
        
           | quickthrowman wrote:
           | > Please don't use Hacker News for political or ideological
           | battle. That tramples curiosity.
           | 
           | https://news.ycombinator.com/newsguidelines.html
           | 
           | You can argue that psychedelics are unsafe without resorting
           | to bringing up ideological COVID culture war stuff.
        
           | skyyler wrote:
           | Can you restate your position in a way that doesn't seem to
           | be a battle in the ongoing Culture War?
        
         | BasedAnon wrote:
         | and it can also be a one-way ticket to schizoville
        
           | amanaplanacanal wrote:
           | Unfortunately, for people who are predisposed, going away to
           | college or falling in love can also trigger a psychotic
           | break. I don't think we would tell people not to do those
           | things though.
        
             | BasedAnon wrote:
             | This is like equating swimming in the middle of the
             | atlantic with swimming at your local leisure center.
        
           | NickC25 wrote:
           | When not done under proper set & setting, yeah.
           | 
           | If you're around people you trust, in a controlled
           | environment, you're not likely to develop schizophrenia.
           | 
           | If you just decide randomly to trip in an unknown environment
           | with people you're not comfortable around, yeah, it's going
           | to be a wild ride and you might not ever truly get off it
           | even after the stuff wears off completely.
        
             | BasedAnon wrote:
             | > When not done under proper set & setting, yeah.
             | 
             | Sorry but this is the biggest load of garbage. You can do
             | everything right, and still come away with trauma and psych
             | issues. It's like writing randomly to memory from ring 0
             | and hoping you don't irreversibly wreck your install.
        
             | seabird wrote:
             | Things can just go bad, no matter how hard you try. There
             | is always some level of risk involved, especially if you
             | have a family or personal history of mental illness, in
             | which case it's advisable to not fuck with it at all. "Set
             | and setting" doesn't paper over everything.
        
               | aaomidi wrote:
               | Isn't this generally the case for everything?
               | 
               | Things can go bad in any experience.
               | 
               | You can go zip lining and things can go bad. You can go
               | through any experience and can be left with various
               | degrees of physical and mental damage.
               | 
               | Does that mean we shouldn't do anything?
        
               | BasedAnon wrote:
               | Risks are not created equal.
        
               | aaomidi wrote:
               | Never implied they are but neither are the rewards.
        
               | seabird wrote:
               | The risk of psychedelic drugs is more comparable to
               | motorsports, the more involved action sports, heavy
               | equipment operation, etc. and your average person would
               | be very wary of participating in these even though there
               | are plenty of risk mitigations for these activities.
               | 
               | I'm not saying you shouldn't do drugs. I'm saying that
               | many of them require way more respect than most people
               | realize they need to give them, and trying to downplay
               | that is not good. I can tell you from personal experience
               | that it's easy to get yourself and people you care about
               | in dangerous places.
        
               | chrisldgk wrote:
               | Speak for yourself, I'd hop into (and probably crash) a
               | formula 1 car no questions asked
        
               | hellotomyrars wrote:
               | To be fair it's not a good comparison. An F1 car is , all
               | things considered, an incredibly safe place to be in.
               | 
               | Certainly safer than your average road car in most
               | circumstances.
        
               | seabird wrote:
               | I would too, but most people get nervous revving their
               | car past 4k.
        
           | DueDilligence wrote:
           | [dead]
        
       | Georgelemental wrote:
       | Not everyone reacts the same way to psychedelics. One person
       | might have a "mind-opening experience" for an hour and then be
       | fine, another might suffer from permanent vision problems or
       | worse.
        
       | Wonnk13 wrote:
       | I completely agree, but this stuff is still illegal in most of
       | the United States. What am I supposed to do, just walk up to
       | someone "how do you do fellow kids, I'd like to purchase one
       | LSD".
        
         | belfalas wrote:
         | If you live in San Francisco, simply walk up and down Haight
         | for a while (near Ashbury, of course). Look for "street
         | characters" - every once in a while as one of them passes you,
         | they'll quickly call out "hey man, wanna buy shrooms?" and keep
         | walking. The expectation is that if you want to buy you'll go
         | shoulder tap them.
        
         | beerpls wrote:
         | Stop living your life under the ruse that is our
         | government/capitalist elites and start living it for yourself
         | 
         | The drugs will come naturally after that (if you want them to)
        
         | greyface- wrote:
         | For psilocybin: learn what mushrooms grow in your area and how
         | to identify them, go for a walk, keep your eyes open.
        
           | p_j_w wrote:
           | Alternatively, grow them yourself.
        
         | capableweb wrote:
         | This wasn't what I imagined myself doing this morning, but here
         | is a shortened step-by-step guide how to acquire psychedelics
         | as an adult:
         | 
         | - Get Tor browser and find one of the various marketplaces,
         | purchase small samples and send part of the sample to one of
         | the various test labs that can confirm the quality
         | 
         | OR
         | 
         | - Find a community where people are likely to have some sort of
         | experience with psychedelics, like self-improvement groups,
         | hacker spaces or just visit raves
         | 
         | - Start talking with a person who could maybe possibly have
         | done psychedelics at one point or another. Don't ask them
         | outright about buying, but starts a conversation about your
         | curiosity around psychedelics for self-help.
         | 
         | - If they reciprocate, you can at one point of the conversation
         | ask them kindly if they happen to know anyone who can sell to
         | you. If they say no, just move on with the conversation as to
         | not make anything awkward for either of you
         | 
         | - Repeat until you find someone, you'll find someone for sure,
         | in either of the groups mentioned before.
        
           | TrainedMonkey wrote:
           | It's amazing how much of how-to-get-drugs-advice is be social
           | and talk to people. Props for including the technical
           | solution too!
        
             | capableweb wrote:
             | Hah, true :) I think "talk to others" is often a solution
             | that is overlooked and is very powerful. Probably the best
             | parts of my life wouldn't be possible if I didn't force
             | myself to socialize with others, even if it's difficult and
             | I don't want to do it until after the socialization is done
             | then I feel good about it.
        
               | toast0 wrote:
               | Ugh, even Power Magazine told us "talk to everyone", but
               | I'd rather not. :P
        
           | galaxyLogic wrote:
           | > Start talking with a person who could maybe possibly have
           | done psychedelics
           | 
           | Clue: If they are a guy with long hair. Or if they are a gal
           | they might have flowers in their hair
        
             | pessimizer wrote:
             | Better clue: if you're friendly with them and they've
             | talked about doing psychedelics.
        
             | swores wrote:
             | Having known a few people of those two physical
             | descriptions, and quite a few people who've used
             | psychedelics, in my small sample set you'd be looking at
             | the wrong people.
             | 
             | Change "long hair male" to "dreadlocks on a white male" and
             | you'd have a point, but the majority of long-haired men
             | I've known either wouldn't do drugs or are into non-
             | psychedelics.
             | 
             | And having spent a lot of time in clubs/festivals/house
             | parties around drug use, of the many many users and dealers
             | of psychedelics I've met... I don't think I could narrow
             | down a single "look" that's more, or less, likely than any
             | other.
             | 
             | On the other hand, a) there is "a look" to facial
             | expressions (not dissimilar to a weed "stoned" or amazed
             | expression) that can be quite recognisable of somebody
             | being under the influence - aided by things like super wide
             | pupils and b) there are activities - such as being in a
             | place where people are dancing to electronic music of some
             | genre - where plenty of people use psychedelics and those
             | faces can often be seen (though easily confused with
             | expressions caused by other classes of drug).
        
             | capableweb wrote:
             | I'd probably go by more of non-visual characteristics
             | (openness, uncommon worldviews, unusually emphatic and so
             | on) rather than just visual clues, but YMMV
        
               | toast0 wrote:
               | It's hard to identify people to start talking to with
               | those characteristics, as many of them are only apparent
               | after you're in conversation.
        
         | explaininjs wrote:
         | A friend of mine named Craig has a List of places you might
         | find such items.
         | 
         | Definitely always remember test kits are your friend.
        
         | briffle wrote:
         | Take a vacation to Oregon...
        
         | rocketbop wrote:
         | Telegram is a good place to order drugs in many cities. Just
         | look for groups near you and there's a good chance you'll find
         | an active group advertising their warez. You can DM them and
         | likely they'll deliver, cash on delivery.
        
       | mahnen wrote:
       | Unrelated -> Why astronomers like to get high
       | 
       | https://www.youtube.com/watch?v=v4T94Rt1tK0
        
       | doc_gunthrop wrote:
       | Reminds me of how Carl Sagan wrote about his experiences with
       | cannabis usage (under the pseudonym Mr. X, as to avoid the social
       | stigma associated with it at the time).
        
       | pie420 wrote:
       | The final frontier
        
       | pookha wrote:
       | If you're predisposed to schizophrenia, pure bi-polar or other
       | mental health issues you probably shouldn't be tripping balls on
       | LSD (https://pubmed.ncbi.nlm.nih.gov/6870484/) or taking THC at
       | high levels
       | (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424288/). Seems to
       | be a major risk.
        
         | hellotomyrars wrote:
         | I am bipolar and can not tolerate these substances. It is very
         | bad for me.
         | 
         | I'm happy to let people enjoy them but it is not something I
         | can do. It does bother me when people say that they're all
         | harmless with no problems though. As with all things there are
         | adverse reactions and it's irresponsible to claim otherwise. I
         | don't advocate prohibition to be clear, just actual truth and
         | honesty.
        
         | Spivak wrote:
         | Also there is a (small) risk that you can't really check for in
         | advance that lsd will just give you tinnitus, ask me how I
         | know. I'm told it might go away in about a year.
        
       | TheLoafOfBread wrote:
       | Somebody was watching Fringe
       | https://en.wikipedia.org/wiki/Fringe_(TV_series)
        
       | mcculley wrote:
       | I am always amused that the discourse around LSD uses the term
       | "microdosing". We know that tiny doses can harm and hurt humans.
       | Claiming that many uses are "microdoses" is rationalization.
       | 
       | Edit: I meant to say "harm and help", not "harm and hurt".
        
         | _a_a_a_ wrote:
         | > We know that tiny doses can harm and hurt humans
         | 
         | Evidence? (Other than tiny doses of anything potentially can
         | cause harm and hurt, assuming harm and hurt are 2 different
         | things, not perhaps the same thing repeated in different ways
         | to make an emotive appeal)
        
         | pessimizer wrote:
         | You seem to know of a discourse where "microdose" implies that
         | something has no effect. Why would they be taking it if it had
         | no effect?
         | 
         | > We know that tiny doses can harm and hurt humans.
         | 
         | We don't know that tiny doses of LSD can harm or hurt humans.
         | What we do observe is that smaller amounts of things tend to
         | have smaller effects than larger amounts of things.
        
         | xXTyrannosXx wrote:
         | The dose for LSD to be harmful is extremely high and you would
         | likely never encounter anyone selling anywhere close to the
         | amount needed. The biggest threat to the user is the
         | contamination of the LSD by possibly fentanyl or other opiates
         | due to the unregulated nature of the black market.
        
           | klyrs wrote:
           | On a previous thread here about LSD I learned about NBOMe --
           | it's a hallucinogen that's sold on paper tabs; if a dealer
           | (or their supplier) is unscrupulous they might sell it as
           | LSD. Only problem? Where psychonauts feel comfortable eating
           | mouthfuls of LSD tabs, the difference between noticeable and
           | harmful doses is quite small with NBOMe.
           | 
           | https://en.wikipedia.org/wiki/25I-NBOMe
        
       | sitkack wrote:
       | Write drunk, edit sober.
       | 
       | Mind altering substances definitely give a new perspective on the
       | problem.
        
       | Phelinofist wrote:
       | [flagged]
        
       | Jazgot wrote:
       | I'm wondering whether experiences with hallucinogens are some
       | form of doing self regularization?
        
         | sixo wrote:
         | Yes in the sense that the aim is to avoid overfitting, and to
         | improve generalization, but here the goal is not to favor
         | simpler models but to avoid them, with the presumption that the
         | observed data is a biased sample of reality, and that our
         | natural model building intuition will not correctly make sense
         | of outliers... That kind of thing.
        
         | extasia wrote:
         | What do you mean by self regularisation?
        
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       (page generated 2023-06-01 23:01 UTC)