[HN Gopher] Low Sexual Satisfaction Linked to Memory Decline Lat...
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       Low Sexual Satisfaction Linked to Memory Decline Later in Life
        
       Author : PaulHoule
       Score  : 23 points
       Date   : 2023-05-30 20:09 UTC (2 hours ago)
        
 (HTM) web link (medicalxpress.com)
 (TXT) w3m dump (medicalxpress.com)
        
       | bell-cot wrote:
       | Obvious Quip: "Nothing that was really worth remembering, eh?"
        
       | m463 wrote:
       | I thought there was a study that showed sildenafil helped prevent
       | cognitive decline too.
       | 
       | I wonder if it's all just atherosclerosis causing not only
       | erectile dysfunction but also cognitive decline.
       | 
       | EDIT: Sildenafil for the Treatment of Alzheimer's Disease: A
       | Systematic Review
       | 
       | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242821/
        
         | DiabloD3 wrote:
         | That's my pet theory as well: the standard American diet (SAD)
         | is low in both Vitamin C (which is used as enzymatic cofactor
         | in dozens of reactions, and is also necessary to build
         | collagen) but also low in Vitamin K2 (necessary in formation of
         | MGP, a calcification inhibitory protein used in cartilage and
         | arterial walls; amongst other things).
         | 
         | Like, I bet merely a lifetime of supplementation of Vitamin C
         | and K2 and sufficient D (2000-5000 IU, not the sub-1000 IU
         | bullshit amounts) would see a lot of these modern diseases just
         | vanish into thin air. These are _extremely_ inexpensive to
         | supplement, a tiny insignificant fraction of all the ED drugs,
         | all the blood thinners and surgeries done on people with
         | clogged arteries and heart disease, and all the expensive end
         | of life care done on people with Alzheimers and other cognitive
         | decline.
         | 
         | But, yeah, just a pet theory.
        
           | tracker1 wrote:
           | I think it goes a bit beyond that... I mean, I think the
           | nutrition related to fat soluble vitamins heavily correlates
           | to the quality/types of fats taken in. There's a lot more
           | nutrition in animal sources of fatty acids than in typical
           | seed oils and the distribution model is very different as
           | well. Since these are used for cellular and hormone
           | generation, I think the "low fat" craze and anti saturated
           | fat and anti dietary cholesterol combined with a general
           | religious approach to veganism has lead to some generational
           | declines.
           | 
           | I'm of a pretty firm belief that the typical healthy person
           | should probably be getting around 40% of their nutrition from
           | animal sources, and not in particular be afraid of natural
           | fats nearly as much as refined foods in general.
           | 
           | It only took a couple generations of domesticated cats to
           | show the decline from dietary changes, I think it's just
           | taken a bit longer for industrial "food" to start showing the
           | extent of issues in the general western populations.
           | Supplementation helps, but the supplements need to be the
           | actual variations the body absorbs, not precursors that are
           | typically used.
           | 
           | In the end, I think the base causes of ED and sexual
           | dysfunction is largely simply the same as mental health in
           | general with age, along with metabolic and cardiovascular
           | issues generally speaking. Too much refined sugar, fructose
           | and low quality protein and fats across generations.
        
           | PaulHoule wrote:
           | I took K2 and my blood pressure almost doubled. Seems like
           | dangerous stuff to me.
        
             | DiabloD3 wrote:
             | Sounds like something you should bring up with your doctor.
             | 
             | The only thing I've ever seen is a link between
             | specifically MK7 (currently only sourced from Natto; MK4 is
             | what you normally see in all other fermented foods and the
             | majority of K2 supplements; MK7 supplements are very
             | expensive comparatively) combined with large doses of
             | flavonoids (often found in Vitamin C complexes).
             | 
             | I have not seen this mentioned in a study, but I suspect
             | the combination of both may be an issue for a minority of
             | people. Lowering the dose or switching to a more
             | conventional MK4 lowered their BP back to normal.
             | 
             | As with any supplementation, no matter how innocent, always
             | keep a Doctor handy to run labs: the difference between
             | screwing around and science is keeping notes.
             | 
             | That said, studies like https://journals.lww.com/md-
             | journal/Fulltext/2021/06110/Vita... and
             | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230802/ seem
             | to indicate that even MK7, as opposed to just MK4, should
             | be strongly considered for inclusion in the common
             | multivitamin.
        
         | mikestew wrote:
         | _I thought there was a study that showed sildenafil helped
         | prevent cognitive decline too_
         | 
         | That rings a bell, but I wouldn't be able to find it quickly. I
         | wouldn't be surprised regardless, as sildenafil, like many
         | erectile dysfunction drugs, started as a heart drug anyway
         | (what _kind_ of heart drug, I am not qualified to answer).
         | 
         | At the same time, perhaps sildenafil users are understandably
         | more sexually satisfied, and we have then come full circle to
         | TFA.
        
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       (page generated 2023-05-30 23:02 UTC)