[HN Gopher] Clinical validation of a blood-pressure sensor for c...
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Clinical validation of a blood-pressure sensor for continuous
health monitoring
Author : bookofjoe
Score : 62 points
Date : 2023-05-21 15:28 UTC (1 days ago)
(HTM) web link (onlinelibrary.wiley.com)
(TXT) w3m dump (onlinelibrary.wiley.com)
| midland_trucker wrote:
| I'm yet to see a study that convinces me of the potential of this
| concept. All of them when you get down to the details have at
| least one of: - An unrepresentative test set ,
| i.e. a population with similar blood pressure at recording in
| which merely predicting a constant 'typical' reading would
| perform well in terms of accuracy. - A major methodology
| flaw, such as 'demonstrating' an ability to detect fluctuations
| from a baseline calibration cuff reading in situations where you
| would expect no significant fluctuations to occur.
|
| I don't have access to this particular paper, but suspect it has
| the same issue owing to the relatively small sample size.
| z3ugma wrote:
| I'm not surprised this works - accurate cuffless blood pressure
| has been validated from other physiological sources like PPG /
| pulse oximetry.
| https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141397/
|
| and is even now FDA-cleared for clinical use: e.g.
| https://www.bio-beat.com/post/the-biobeat-cuffless-wrist-blo...
| jsharf wrote:
| Wait isn't PPG for heart rate?
| throwaway5752 wrote:
| Not specifically. Photoplethysmography just means, roughly,
| light based volume measurement. It can measure pulse when
| done crudely. If you have a baseline for blood pressure and a
| sensitive enough PPG sensor you can detect different levels
| of volume and infer pressure. It is analogous to measuring
| water pressure based on the diameter of a filled rubber hose.
|
| To the GP's point, the largest blood pressure monitor company
| is Omron. Portable monitors have been around. https://www.omr
| on.com/global/en/technology/omrontechnics/vol... is a good
| place to learn more about the advantages and disadvantages of
| different approaches. Piezoelectric and PPG would have the
| advantage of lower cost, lower mechanical complexity, and
| continuous monitoring instead of point measurements.
| felideon wrote:
| > Portable monitors have been around.
|
| Not reliable/valid _cuffless_ monitors, though. That 's
| relatively new, if I understand correctly.
| abnry wrote:
| I love wearables. It is a pain in the neck to take a measurement.
| Anything that can be worn and sense automatically is awesome. I
| studious update an SQLite database of my Fitbit data. I just wish
| I had more measurements to track!
| ijustlovemath wrote:
| This is a very early stage study; at 175 data points over 35
| patients, that's just 5 data points per person. Barely enough to
| make a convincing linear regression.
| felideon wrote:
| It'd be interesting to read the study limitations, but, at 35
| participants, a larger and diverse cohort would be warranted to
| see how this translates in the real world.
|
| Aktiia has done some studies for its product and works by taking
| a BP cuff measurement to calibrate its PPG sensor-based
| algorithm. If you can get rid of the cuff and can sell an
| affordable wearable device, that would be a promising future.
| LorenPechtel wrote:
| The Aktiia device only required periodic recalibration with the
| cuff. We'll see if it makes it through the FDA.
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(page generated 2023-05-22 23:01 UTC)