[HN Gopher] Things I Won't Work With: Thioacetone (2009)
       ___________________________________________________________________
        
       Things I Won't Work With: Thioacetone (2009)
        
       Author : chris_overseas
       Score  : 146 points
       Date   : 2023-02-25 09:47 UTC (13 hours ago)
        
 (HTM) web link (www.science.org)
 (TXT) w3m dump (www.science.org)
        
       | lwansbrough wrote:
       | A YouTuber went to the trouble of making it.
       | https://youtu.be/LmAG8-V_WQY
       | 
       | He ends up doing the final step of the process on an uninhabited
       | island in the middle of a lake for safety.
        
         | chrisdalke wrote:
         | He seemed to not react too much to the smell. With all the
         | other crazy stuff he does, he must be seriously desensitized to
         | strong smells if that's even possible...
        
           | VLM wrote:
           | covid related loss of smell perhaps?
        
             | piyh wrote:
             | Loss of smell due directly inhaling ammonia
        
             | Sharlin wrote:
             | You think the chemists were time travelers?
        
               | rootusrootus wrote:
               | The video was made in December 2022.
               | 
               | But still, the covid hypothesis seems extremely
               | farfetched. Desensitization from exposure I could
               | believe.
        
               | Sharlin wrote:
               | Oops, thought GP's reply was to another comment.
        
           | ogisan wrote:
           | In the article: "The odours defied the expected effects of
           | dilution since workers in the laboratory did not find the
           | odours intolerable."
        
             | rsfern wrote:
             | I think that bit is saying the chemists who synthesized the
             | compound were desensitized to it, it's right after a
             | passage where they were ostracized and sprayed with
             | deodorant at a restaurant during lunch
        
               | junon wrote:
               | I don't think so. In NileRed's video it was clear that
               | dilution made the odor _worse_ than bring right next to
               | it, which otherwise invoked a  "chemical"-ey smell rather
               | than a putrid trash+sewage smell.
        
               | CommitSyn wrote:
               | Full quote, which seems to say it defies the expected
               | effects of dilution _because_ the chemists weren't
               | bothered by it when they were right next to it, but when
               | they were many yards away they could.
               | 
               | "The odours defied the expected effects of dilution since
               | workers in the laboratory did not find the odours
               | intolerable ... and genuinely denied responsibility since
               | they were working in closed systems. To convince them
               | otherwise, they were dispersed with other observers
               | around the laboratory, at distances up to a quarter of a
               | mile, and one drop of either acetone gem-dithiol or the
               | mother liquors from crude trithioacetone crystallisations
               | were placed on a watch glass in a fume cupboard. The
               | odour was detected downwind in seconds."
               | 
               | In other words, the smell intensity increases with
               | dilution, _not_ decreases. We must protect this data from
               | the homeopaths.
        
               | black6 wrote:
               | Hydrogen sulfide rapidly desensitized the nose, it
               | wouldn't be surprising for other sulfur compounds to do
               | the same.
        
             | JohnBooty wrote:
             | I've never smelled this chemical, but I wonder if it's a
             | little bit like skunk spray smell?
             | 
             | There's a saying! "Skunks don't have the WORST smell, just
             | the MOST smell"
             | 
             | It's not the worst smell in the world. I would say it's not
             | even remotely as unpleasant as summertime "dumpster soup",
             | sewage, or whatever. But man, skunk smell is just so
             | intense and overwhelming.
        
               | dieselgate wrote:
               | Yes your last sentence all the way
        
               | toomanyrichies wrote:
               | > "Skunks don't have the WORST smell, just the MOST
               | smell"
               | 
               | I did my coding bootcamp in downtown Chicago, near the
               | Merch Mart, and (at least back in 2013) there was a
               | chocolate factory not too far away. I remember walking to
               | class and being almost overpowered by the smell. For
               | awhile it turned me off of chocolate entirely, and I
               | normally have a pretty strong sweet tooth.
               | 
               | I remember feeling so sorry for the people who had to
               | work there, day after day.
        
               | sandworm101 wrote:
               | >> chocolate factory
               | 
               | Soup factories are notorious for smells. A single pot of
               | cooking food generally smells good, but layer up a dozen
               | different soup flavors and in total it smells like rot.
        
               | culebron21 wrote:
               | I live in 3 blocks from a chocolate factory, and don't
               | find it disturbing. Rather nice. The first time I felt it
               | at a marketplace nearby, and thought someone was making
               | some hot chocolate stuff, and even wanted to take a look
               | what it was, but couldn't find. Sometimes it gives a mild
               | chocolate smell around, nothing more.
        
               | masklinn wrote:
               | > I remember feeling so sorry for the people who had to
               | work there, day after day.
               | 
               | As a kid one of the tours we did was a chocolate factory.
               | When the person leading the tour told us the employee
               | told us workers were allowed to take as much chocolate as
               | they wanted we were super jealous.
               | 
               | At the end of the tour, there was a buffet of chocolate
               | snacks nobody wanted to touch (though we were allowed to
               | and did bring bags of products home), the person told us
               | that after a day of working at the factory, most workers
               | have no taste for chocolate snacks whatsoever, and those
               | which do will generally fuck up, binge, get an
               | indigestion, and at best be a lot more reasonable (at
               | worse stop eating chocolate if it was bad enough).
               | Without the allure of the forbidden fruit (sneaking
               | snacks out), chocolate is definitely overpowering enough
               | that it's a turn-off.
        
               | dclowd9901 wrote:
               | When my dog got sprayed by a skunk, it smelled
               | overwhelmingly like a combination of burning rubber and
               | rotten motor oil. Neither of these brands of smells is
               | the worst I've ever encountered from a pure quality
               | standpoint, but yes, it felt like it completely coated
               | your nasal and throat passages. You choke on it.
        
               | culebron21 wrote:
               | Oh, dogs and smells, this makes me remember my poodle
               | who, as every dog, would routinely look for stinky stuff
               | to lay in. Once he found a dead cat -- it was rather
               | nasty to wash him in the bath after that. Another time he
               | was running around and found a rot fish thrown away near
               | a trash tank -- this was the smelliest washing ever. Had
               | to wash him twice with soap, then with shampoo. Another
               | time, in winter, there was parking area covered with hard
               | snow, compacted by car tires. And he laid and started
               | rolling on a seemingly featureless spot. It turned out,
               | some diesel fuel had been spilled there.
        
           | world2vec wrote:
           | Yeah his nose doesn't feel anything anymore. But the
           | cameraman had a rough time in that island.
        
         | rini17 wrote:
         | And of course, since selenium compounds are said to smell even
         | worse...
         | 
         | https://www.youtube.com/watch?v=031vrZAMEHU
        
           | lovehashbrowns wrote:
           | Ugh okay I'm gonna try to buy some from him and see what it
           | smells like.
        
           | pancrufty wrote:
           | Selenium stinks alright
        
           | jojobas wrote:
           | The moment I saw that I knew I had to reproduce that. Turns
           | out you can just buy all the required stuff.
        
         | cheshire137 wrote:
         | Lol I knew before clicking it would be NileRed.
        
           | martin_a wrote:
           | I didn't really like chemistry in school, but NileRed makes
           | me wish it was different. Great guy!
        
       | actually_a_dog wrote:
       | I'm a little disappointed by this article. After all, I'm sure
       | the author knows that anything that stinks with sulfur can be
       | made stinkier by substituting selenium! Selenoacetone is worse
       | than thioacetone!
       | 
       | https://www.youtube.com/watch?v=031vrZAMEHU
        
       | amelius wrote:
       | Is this the stuff they use in legal pepperspray alternatives (in
       | places where pepperspray is not legal)?
        
         | jandrese wrote:
         | More likely to be methyl mercaptan as that is frequently used
         | as an odorant and is available from chemical suppliers.
        
         | nibbleshifter wrote:
         | Not that I'm aware of.
         | 
         | It would be classed the same as pepper spray in the UK (a
         | "noxious chemical").
         | 
         | The skunk lock and similar products that use a malodorous
         | chemical are illegal in the UK for this reason.
         | 
         | There are "self defense sprays" sold in the UK and some other
         | countries that just contain a dye, no irritant or malodorous
         | substance, but even those are legally questionable at best -
         | just there's been no case law yet that I'm aware of.
        
           | galangalalgol wrote:
           | That all seems a bit excessive doesn't it? Does that mean you
           | can't carry a pocket knife either? I would be lost without my
           | Leatherman or at least a swiss army knife.
        
             | nibbleshifter wrote:
             | Yes, it is excessive.
             | 
             | The UK is highly restrictive, in so many ways.
             | 
             | As for knives in the UK: so long as the blades under 3
             | inches long, and it is a non locking folding knife, it is
             | legal to carry in public (with some exceptions).
             | 
             | Any knife longer than 3 inches, or any knife with a locking
             | blade, cannot be carried unless you have a good reason (eg:
             | going to/from work, etc).
             | 
             | You likely will have to argue this reason in court if the
             | police officer is a cunt, and most of them are cunts when
             | it comes to having common sense around blades.
             | 
             | Fixed blade knifes of any length require a "good reason" to
             | carry.
             | 
             | A lot of coppers in the UK are ignorant as fuck too, and
             | will confiscate your folding, non locking, sub-3 inch Swiss
             | army knife requiring you to jump through burning hoops,
             | wade through an ocean of piss, and sacrifice a virgin goat
             | at midsummar to get it back.
        
               | galangalalgol wrote:
               | At the other end of the spectrum my kid can walk around
               | with a machete and be perfectly legal, but her school
               | library can't have V for vendetta. Is there anywhere that
               | doesn't nanny about access to ideas _or_ "weapons" (I'd
               | rather use an umbrella as a weapon than a Leatherman if
               | it came to it).
        
               | nibbleshifter wrote:
               | I have no idea if anywhere exists that doesn't have
               | _some_ nanny state bullshit going on.
        
               | rcarr wrote:
               | In defence of the police officers, you are probably
               | dealing with similar level of anxiety as soldiers. I
               | imagine a high number of them have had to deal with a
               | knife incident and just because you've got a taser, some
               | training and some backup doesn't necessarily mean it's
               | going to end well for you. There are quite a few reports
               | of people (especially large blokes like rugby players)
               | who can shrug off a taser and go on a rampage. It
               | famously took 20 police officers to arrest Eddie Hall and
               | that was before he became a professional strongman.
               | 
               | I've heard the expression "don't go into a knife fight
               | and expect to come out uncut". As in, even if you win,
               | there's a high likelihood you're going to have slash
               | wounds on some part of your body somewhere. Yes a bit of
               | common sense should be in order but I can also understand
               | why they want to be very strict about these things.
               | Having to deal with a knife fight and the aftermath
               | probably isn't a great day at work.
        
               | amelius wrote:
               | > cannot be carried unless you have a good reason (eg:
               | going to/from work, etc).
               | 
               | Sounds like you can easily get around any problems by
               | just saying you are heading for work.
        
               | nibbleshifter wrote:
               | The problem is, if the officer doesn't believe your
               | reason is good enough, you end up having to go to court
               | over it - which is expensive, and you may well lose and
               | catch a custodial sentence.
               | 
               | I can't really overstate how ridiculous the UK's laws
               | around knives are.
               | 
               | Even tradesmen with glaringly obviously valid reasons to
               | carry knives are recommended to lock them securely in a
               | toolbox while not at the jobsite to avoid prosecution.
        
               | amelius wrote:
               | Perhaps wrap it in gift-paper then :)
        
             | RF_Savage wrote:
             | Most likely not.
        
       | voxadam wrote:
       | If you're interested in other terrifying compounds be sure to
       | read _' Ignition'_.[0]
       | 
       | My footnote is for a scan of the original printing but I believe
       | the book has have recently been reprinted in multiple formats.
       | Regardless of the format you choose, it's a hell of a read.
       | 
       | [0]
       | https://library.sciencemadness.org/library/books/ignition.pd...
        
         | Cthulhu_ wrote:
         | I've tried to read it, and while I can see it's an entertaining
         | read, at the same time it reads like a long string of chemical
         | compounds and formulas being read. I'd only recommend it if you
         | have a better grasp of and interest in chemistry than I have.
        
           | masklinn wrote:
           | From my recollection (I haven't re-read it recently), it's
           | pretty easy to skip the raw chem stuff if you're not
           | interested.
           | 
           | Though that may be a skill I acquired from my youth misspent
           | reading Alexandre Dumas and Jules Vernes (as writers of
           | serials, padding chapters was a very common occurrence which
           | makes for frustrating reads when you hit 5 pages of fishes in
           | 20000 leagues under, the ability to quickly skim and skip is
           | necessary to reach the end).
        
           | mhb wrote:
           | I agree. I muddled through it because the non-technical 25%
           | made it worthwhile and the writing was very nice.
        
       | mnemotronic wrote:
       | Sounds like a possible weapon. Not fatal or toxic but certain to
       | temporarily disable troups downwind.
        
         | jamiek88 wrote:
         | Aaand you've just hit the problem with chemical weapons.
         | 
         | Wind shifts.
         | 
         | Before you know it your own troops are vomiting and choking on
         | their uvulas.
        
       | EdwardCoffin wrote:
       | Anyone thinking this might have potential as an unconventional
       | weapon might find it interesting to read Neal Stephenson's
       | _Zodiac_. The protagonist, a chemist-turned-environmental-
       | activist, makes some Putrescine (a similarly stinky substance)
       | for self defence.
        
         | sokka_h2otribe wrote:
         | Hmmm, I believe I first invented the stink bomb in avatar the
         | last Airbender
        
       | AlbertCory wrote:
       | For a not-all-that-fun time, go to eBay and search on that.
       | 
       | there was one answer, and it was for a prank device to _detect_
       | that.
       | 
       | Plus I got a box inviting me to select the vehicle type this was
       | for. I took one, and got a lot of miscellaneous stuff having
       | nothing to do with thioacetone.
        
       | pdpi wrote:
       | If this is your first time reading one of these, Derek Lowe's
       | "things I won't work with" series is a great way to spend a
       | Saturday afternoon.
        
         | memling wrote:
         | FOOF is my favorite. Come for an analysis of Streng's papers
         | and stay for Satan's kimchee.
        
           | rwmj wrote:
           | FOOF - https://www.science.org/content/blog-post/things-i-
           | won-t-wor...
        
           | erik_seaberg wrote:
           | I first read https://www.science.org/content/blog-post/sand-
           | won-t-save-yo... so I will always have a soft spot for it.
           | 
           | "[...] it can potentially go on to "burn" things that you
           | would normally consider already burnt to hell and gone, and a
           | practical consequence of that is that it'll start roaring
           | reactions with things like bricks and asbestos tile."
        
             | robinsonb5 wrote:
             | That was my introduction to the series, too - certainly a
             | classic! (I have a vague recollection that it was linked to
             | from DansData at some point, but couldn't swear to it.)
        
             | jiggawatts wrote:
             | If you keep researching, it's a fun rabbit hole of the
             | Internet to go down. The Material Safety Data Sheet from
             | one of the few(!) manufacturers is... something else.
             | 
             | The MSDS warnings for ClF3 read like the State Department
             | travel advisory warnings for Bhakmut.
        
           | cushychicken wrote:
           | _At seven hundred freaking degrees, fluorine starts to
           | dissociate into monoatomic radicals, thereby losing its
           | gentle and forgiving nature._
           | 
           | Referring to fluorine's "gentle and forgiving nature" got a
           | good laugh out of my wife, who has a chemistry degree. It
           | also got me a good education about just how gross elemental
           | fluorine is.
        
           | ikiris wrote:
           | F is for Flags, they be of red.
        
         | bayouborne wrote:
         | The collection:
         | 
         | https://www.science.org/topic/blog-category/things-i-wont-wo...
        
           | LoganDark wrote:
           | Thank you for this link! Always wanted to read the whole
           | collection.
        
       | russfink wrote:
       | PSYOPS potential?
        
       | mywacaday wrote:
       | How are smells transferred and detected far away after a few
       | seconds when the air is not moving that fast?
        
       | Sniffnoy wrote:
       | (2009)
        
         | _a_a_a_ wrote:
         | Relevant? Not sure noses have evolved much in 14 years :)
        
           | Kye wrote:
           | It's required for submissions older than the current year.
           | It's not in the guidelines as far as I know, but people will
           | complain (rightly in most cases) and the headline will
           | magically change to include it.
        
             | _a_a_a_ wrote:
             | My impression is people complain only if it's news that
             | ages, this isn't.
             | 
             | ---
             | 
             | "Romani Invadest Albion!"
             | 
             | > Please add 40BC to the title
             | 
             | ^^ like that
        
               | brookst wrote:
               | How many Romans?
        
           | dclowd9901 wrote:
           | Speak for yourself. I've had two kids in that time.
        
       ___________________________________________________________________
       (page generated 2023-02-25 23:01 UTC)