[HN Gopher] Why Is Colorectal Cancer Rising Rapidly Among Young ...
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Why Is Colorectal Cancer Rising Rapidly Among Young Adults?
Author : paulpauper
Score : 77 points
Date : 2023-02-07 19:57 UTC (3 hours ago)
(HTM) web link (www.cancer.gov)
(TXT) w3m dump (www.cancer.gov)
| anthk wrote:
| Lots of food from the US it's banned in the European Union with a
| good reason.
| jandrewrogers wrote:
| Lots of food from the EU is banned in the US for safety
| reasons.
| conductr wrote:
| Generally US is concerned with lack of preservatives and EU
| is concerned with use of fake preservatives
| tohnjitor wrote:
| Could anal sex be linked to this?
| HPVadvisory wrote:
| actually all sex. skin to skin contact, oral sex, penetrative
| sex, they are all ways HPV can lead to prostate cancer, anal
| cancer, ovarian cancer, and throat cancer. from any given point
| of entry.
| rawicki wrote:
| That's more likely anal than colon cancer.
|
| If you are bottoming a lot you can consider screening for that
| every 1-3 years.
| 60secs wrote:
| Not eating enough beans
| voisin wrote:
| Not sure why you are being downvoted. I think fibre intake is
| absolutely correlated to colorectal cancer.
| wavy-dingo wrote:
| Inversely correlated? As in, more beans is less cancer?
| HPVadvisory wrote:
| beans dont prevent HPV, the leading cofactor of anal cancer.
| marl0 wrote:
| Start with rinsing your dishes and try not to eat out.
|
| https://www.jacionline.org/article/S0091-6749(22)01477-4/ful...
|
| Detergents, preservatives, pesticides and low quality ingredients
| are all great examples of things you can cut out eating at home.
| While we don't seem to have enough data to point to each one of
| them individually, it seems pretty common sense these are the new
| contributing factors in our environment.
| m0llusk wrote:
| Lectins, specifically gluten, are strongly associated with IBS.
| Many people have found relief from IBS by reducing or
| eliminating lectins in their diet, especially gluten. It is
| worth pointing out that wheat is an extremely common ingredient
| nowadays, but most of the wheat we grow and eat is no longer
| the traditional emmer or einkorn but a dwarf hybrid that among
| other differences produces extreme amounts of gluten.
| adrian_b wrote:
| What you say is true, but the hybrid wheat rich in gluten has
| already existed for a few millennia and during all this time
| it has been the main staple food for hundreds of millions or
| even for billions of people, who have suffered no undesirable
| consequences from it.
|
| Nowadays it seems that there are more and more people that
| are affected negatively by gluten consumption. Because this
| was much less frequent in the past, there must be an
| additional unidentified factor that causes gluten sensitivity
| and which has not existed formerly.
| genocidicbunny wrote:
| > who have suffered no undesirable consequences from it.
|
| Is that really the case? I suspect it was more that people
| who had IBS or gluten sensitivity in the past just...died.
| If there was no understanding of the problem, then those
| suffering from it probably appeared to have something like
| dysentery, and would like just be lumped in with everyone
| else that had similar symptoms from various causes.
| jakewins wrote:
| This seems exactly inversed?
|
| Emmer contains twice as much gluten as modern wheat according
| to this summary paper of chemical composition, see table 3:
| https://www.researchgate.net/profile/Anna-
| Zaparenko/publicat...
| adrian_b wrote:
| While most emmer varieties have indeed more gluten than the
| hexaploid wheat, the varieties described in the article
| quoted by you have, as written in the article, between 30%
| and 40% more gluten.
|
| Nowhere in this article an emmer with twice more gluten is
| mentioned.
| hinkley wrote:
| GF support groups are full of tales from people who were able
| to eat wheat in Europe but not NA.
|
| What they don't tell you about wheat very often is that
| people figured out that if you defoliate a wheat plant, it
| will shove its remaining calories into the developing seeds
| and then die. You can control the maturity of a wheat field
| by spraying it with RoundUp late in the season.
|
| So where the reality versus PR for the decay rate of RoundUp
| in the environment leaves a very long safety margin with
| early season and pre-emergent uses of the stuff, whatever you
| sprayed a matter of weeks before harvest very much matters on
| variance between fields and between customer and
| manufacturer.
|
| We may be feeding ourselves RoundUp here.
| UncleOxidant wrote:
| Yes, we know that RoundUp has a negative effect on gut
| bacteria.
| jakewins wrote:
| Isn't that article contradicting your point? They weren't able
| to find any effect for dish detergent, and the effect they did
| find for rinse aids was not present at the concentrations used
| in residential dishwashers?
| cameldrv wrote:
| I just checked, and my detergent (Finish Quantum) has alcohol
| ethoxylates in it. I wonder if with newer high efficiency
| dishwashers that use less water, this stuff isn't getting
| rinsed off as well.
| more_corn wrote:
| Wait we're supposed to avoid soap now? Wtf
| ZyanWu wrote:
| We're supposed to avoid eating it
| brookst wrote:
| NOW you tell me?
| Alex3917 wrote:
| Of course a lot of the hottest new experimental cancer
| therapies are also pesticides, e.g. artemisinins and
| annonaceous acetogenins.
| HPVadvisory wrote:
| rinsing dishes of excess rinse aid/soap does not prevent HPV,
| the leading cofactor of anal cancer.
| j-bos wrote:
| I understand it's not best practice to ask, but could those who
| downvoted this comment reply with their reasons why?
| [deleted]
| Retric wrote:
| The linked post doesn't support their conclusion.
|
| _This rapid increase is especially puzzling because the rate
| of colorectal cancer has plummeted among older adults--
| largely due to regular colonoscopies and lower rates of
| smoking.
|
| "We don't understand a lot about the causes, the biology, or
| how to prevent early onset of the disease," said Phil
| Daschner, a program director in NCI's Division of Cancer
| Biology. "And that's important to learn more about because it
| may affect [approaches for] the treatment and survivorship of
| early-onset colon cancer."_
| kelnos wrote:
| Because the linked research does not support the point the
| poster is making. The researchers did _not_ find a link with
| dishwasher detergents. They found a link with rinse aids, but
| at quantities and concentrations far higher than you 'd find
| in a dishwasher.
|
| Also, I think we should all be skeptical of someone who says,
| essentially, "Don't want colorectal cancer? Rinse your dishes
| and don't eat at restaurants!" Such a simple explanation for
| colorectal cancer seems suspicious... at best.
| RobertRoberts wrote:
| This comment is on track, and it's amazing that it's gotten a
| single down-vote.
|
| Though I would de-prioritize "rinse your dishes" and say the
| food we eat is more of the issue.
|
| Is there some logical reason you would down vote without any
| explanation or counter argument?
| Supermancho wrote:
| The cited paper is not sufficient to explain the dramatic
| rise. It would have been seen much earlier (since the 50s)
| that the trend was obvious. Putting forth "just do X" is a
| low effort post. It has a paper, which is something, but it's
| far from definitive, although it's phrased as such.
|
| I'm sure someone thought the same as me, but they thought
| clicking the down button was the correct response. I don't
| agree, but I understand that not everyone is put together
| before the coffee kicks in.
|
| I have had 2 quarter-coin sized growths removed from my
| colon. The underlying cause is undiagnosed. They were not
| cancerous, by analysis. I believe the growths started in
| Washington State 6ish years ago and black mold was a
| contributor, with other factors. Growths have not returned.
| Animatronio wrote:
| Black mold contributing to colon growths? Now that's
| something I'd like to read more about! Do you have a link
| to a study?
| HPVadvisory wrote:
| Were you tested for HPV?
| HPVadvisory wrote:
| Before you start mentioning detergents, look at something that
| actually modifies the mitosis of cells: viruses.
|
| With the sexual revolution and online dating apps, there has been
| a sharp rise in the spread and strains of HPV.
|
| From their own website: HPV is the most common cofactor for anal
| cancer in general: https://www.cancer.org/cancer/anal-
| cancer/causes-risks-preve...
|
| Because the test for HPV only commonly exists for women, and not
| men, many women fail to disclose that they have an ongoing
| infection because of the gender imbalance. Obviously both men and
| women are spreading it though.
| arcturus17 wrote:
| I read in an Atlantic piece that there was a "sex recession"
| [1] - many sociological studies show that people are having
| less sex than decades prior. It's counter-intuitive, but the
| data in the article meets my anecdotal observation (and I don't
| even live in the US). Assuming both articles are somewhat
| accurate the correlation would pull in opposite directions.
|
| [1] Why Are Young People Having Less Sex (The Atlantic,
| December 2018,
| https://www.theatlantic.com/magazine/archive/2018/12/the-
| sex...)
| HPVadvisory wrote:
| It may "pull" in the opposite direction but the spread of HPV
| is actually on the rise and we have a cancer epidemic for
| young people: throat cancer and anal cancer in particular.
| Prostate and ovarian cancer seem to still mostly hit people
| in their 50s and beyond (also most often related to HPV).
|
| https://www.cedars-sinai.org/discoveries/an-epidemic-
| ignites....
| rawicki wrote:
| Both men and women can be vaccinated against HPV, but that's
| still not popular enough.
| HPVadvisory wrote:
| Infection by the human papillomavirus (HPV) is the most
| important risk factor for anal cancer. Most squamous cell anal
| cancers are linked to infection with HPV. HPV is a group of
| more than 150 related viruses, the same group of viruses that
| causes cervical cancer, as well as other kinds of cancer. In
| fact, women with a history of cervical cancer (or pre-cancer)
| have an increased risk of anal cancer.
|
| Kind of wild that the linked article fails to mention STIs and
| HPV.
| jeffbee wrote:
| Didn't HPV vaccines cut HPV prevalence by an order of
| magnitude, at this point in everyone under 30 years old?
| Gnarl wrote:
| Subtle hint: thing in back pocket emits physical agent known to
| cause oxidative-stress leading to inflammation & dna damage.
| Colon tissue cell division rapid = more sensitive to said dna
| damage.
|
| More: https://pubmed.ncbi.nlm.nih.gov/26151230/
| alar44 wrote:
| The radio waves emitted by your phone are orders of magnitude
| lower than all the other background radiation you're basking
| in. This is a tech forum.
| knodi123 wrote:
| If the phone in your pocket is troubling, think about how many
| radio stations your car radio can receive- every one of those
| signals is blasting through your body, most of the time! And we
| swim in a sea of wireless router signals, as well.
|
| The issues are wattage and whether the radiation is ionizing or
| not. I think, so far, every reputable study has shown that cell
| phones, radio towers, and wifi routers are utterly harmless to
| the people that use them as intended.
| HPVadvisory wrote:
| cell phones dont spread HPV, the leading cofactor for anal
| cancer.
| jemmyw wrote:
| is the thing in your back pocket a banana?
| msie wrote:
| Alcohol?
| arcturus17 wrote:
| I have worked for one of the world's most important alcohol
| distributors, and have been in contact with high execs in the
| org. They are concerned that young people are not drinking as
| much as before, not the other way around.
| ydnaclementine wrote:
| Alright, let's say I know a friend who could be concerned. What
| is the proper term in Zocdoc to find the right kind of doctor to
| get this checked?
| mbrd wrote:
| I'd start with gastroenterologists. I've started having some GI
| issues recently so I've been seeing one, but there was a 4+
| week wait time to see anyone in my area.
| tracker1 wrote:
| I'm guessing fake foods overloaded with preservatives... much
| like with increased oxidative stress in general.
|
| edit:
|
| noting: "There's mounting evidence linking an unhealthy diet--in
| particular, one high in processed meat and fat, and low in fruits
| and vegetables--to early-onset colorectal cancer."
|
| Sounds like it's the meat/fat/cholesterol myth 2.0 ... Not that
| I'm massively in favor of overly processed meat... but the body
| needs fat... we're still suffering from the hormone production
| issues a half century of disinformation on dietary fat has lead
| to... and the heart disease over a century of processed fats in
| unnatural ratios has lead to.
|
| Fruits and Vegetables are not naturally available year-round,
| anywhere. If you want to choose to be vegetarian, cool... but to
| assume it's meat (part what makes us human for many millenia) and
| not the processed "foods" that didn't even exist 150 years ago is
| just absurd.
| Centigonal wrote:
| IBD (including ulcerative colitis, which increases the risk of
| colorectal cancer dramatically) is also increasing in
| developed/westernized countries.[1]
|
| It's unclear how much of this is is due to changes in diet,
| hygiene hypothesis, or environmental pollutants/endocrine
| disruptors.
|
| I wish we understood this better.
|
| [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020403/
| popotamonga wrote:
| I have UC my doctor told me it just slightly increases the
| chance whereas some years ago they thought it increased a lot.
| Is she lying to me or what
| quartz wrote:
| My family has personally experienced this and it is terrifying
| to learn how little information and how few resources there are
| for young children with IBD.
|
| Right out of the gate you hit the issue that there simply
| aren't many "very early onset IBD" (impacting children under 6
| years old) specialists because historically there were so few
| cases. We've seen well regarded IBD specialists who reflexively
| try to order tests and procedures that their own hospital will
| then refuse to even perform because they can't be done safely
| on young children. The IBD specialists are in general simply
| unfamiliar with young children because of the historical
| rarity.
|
| From the VEO IBD specialists we have worked with they all
| report that the numbers are exploding and no one has any real
| idea why.
|
| On top of that most of the more modern and effective treatments
| for IBD and Crohns aren't approved for young children at all
| and even top tier insurance will fight tooth and nail against
| covering them because their use in children can be considered
| off-label.
| tylershuster wrote:
| Anal sex
| HPVadvisory wrote:
| spreading HPV.
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