[HN Gopher] Acting out dreams predicts Parkinson's and other bra...
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       Acting out dreams predicts Parkinson's and other brain diseases
        
       Author : benbreen
       Score  : 80 points
       Date   : 2023-01-19 16:23 UTC (2 days ago)
        
 (HTM) web link (www.scientificamerican.com)
 (TXT) w3m dump (www.scientificamerican.com)
        
       | blakesterz wrote:
       | Funny this has been known for a long time!
       | "Descriptions of dream enactment by people with Parkinson's are
       | as old as recognition of the disease itself. In James Parkinson's
       | original description, "An Essay on the Shaking Palsy," published
       | in 1817, he wrote: "Tremulous motions of the limbs occur during
       | sleep, and augment until they awaken the patient, and frequently
       | with much agitation and alarm." But despite similar reports over
       | the next two centuries, the connection between dreams and disease
       | remained obscure--so much so that Alda had to convince his
       | neurologist to do a brain scan for Parkinson's after he read
       | about the link in a 2015 news article."
        
         | mythhouse wrote:
         | This isn't just recognition of disease though. Its a prediction
         | that you might get that disease in future.
         | 
         | > Apart from being hazardous to dreamers and their partners,
         | RBD may foreshadow neurodegenerative disease, primarily
         | synucleinopathies--conditions in which the protein a-synuclein
         | (or alpha-synuclein) forms toxic clumps in the brain.
        
       | dathinab wrote:
       | > other underlying condition
       | 
       | or trauma in combination with anxiety disorder causing you to
       | have panic attacks in the night
        
         | Nathanael_M wrote:
         | Aren't these separate things? They seem to be referencing a
         | distinct acting out of specific motions in dreams. Something
         | separate from an unstructured reaction to stress/terror etc.
        
       | ddmma wrote:
       | Started to log as many dreams I can recall mornings on driary.com
       | - wish to index dreams or other possible imagery patterns.
       | 
       | I think durring sleep brain has lot of reparing work to do,
       | similar to mechanic in garage for night shift.
        
       | JPLeRouzic wrote:
       | People who have RBD should not despair, not only there are many
       | ongoing clinical trials, but there are very interesting research
       | done to reverse Parkinson, such as this one:
       | 
       | https://journals.lww.com/neurotodayonline/Fulltext/2020/0806...
        
       | blueridge wrote:
       | Peter Attia had a recent episode about neurodegenerative disease,
       | they talk about dream enactment quite a bit, great discussion:
       | 
       | https://peterattiamd.com/kellyannniotis/
        
       | fithisux wrote:
       | Predicts yes, but does it offer any cure? It is terrible for a
       | person to have his abilities being reduced at a rate and knowing
       | each tomorrow is worse than today. People do not seem to care
       | though.
        
         | nobodyandproud wrote:
         | Preparation, in absence of treatment, is still extremely
         | valuable.
         | 
         | Financials, lifestyle and logistics, helpers for the family,
         | your loved ones mentally and emotionally steeling themselves.
         | 
         | Every responsible adult does this, by the way; the rest leave a
         | mess for their family to handle when they pass away (old age,
         | accident, etc.).
         | 
         | But great preparation requires knowing what's coming or likely
         | to come, as we generally have limited time and resources.
        
       | bfgoodrich wrote:
       | [dead]
        
       | mwint wrote:
       | Headline is a bit unclear, I initially thought it was talking
       | about being awake and showing other people what happened in your
       | dream, like a theatre production. Turns out, it's just (what non
       | scientists would see as) sleepwalking.
        
         | willmw101 wrote:
         | >Turns out, it's just sleepwalking
         | 
         | The piece explicitly states that it is not sleepwalking:
         | 
         | >Not all nocturnal behaviors are RBD. Sleepwalking and sleep
         | talking, which occur more often during childhood and
         | adolescence, take place during non-REM sleep. This difference
         | is clearly distinguishable in a sleep laboratory, where
         | clinicians can monitor stages of sleep to see when a person
         | moves.
        
           | SoftTalker wrote:
           | I think laypeople would not make this distinction.
        
           | mwint wrote:
           | Thanks, clarified.
        
           | kolanos wrote:
           | Don't dreams occur during REM sleep? I am a frequent sleep
           | walker and the times I've been awoken by someone else I was
           | in mid-dream.
        
       | cerol wrote:
       | Funny this is on HN's front page, given that only a couple of
       | days ago I had this dream I got stuck in an elevator and started
       | to smash the doors trying to get out. I woke up and I had just
       | smashed the bedroom window with my bare hands.
       | 
       | I have pretty bad sleep habits, but never had that happened to me
       | (AFAIK, given that I live on my own). That day I was sleep-
       | deprived (3 hours of sleep on the night before), and had
       | exercised a lot (I'm an athlete).
       | 
       | I'm only 27, but I'm still a bit freaked out about the
       | possibility of this being an early sign of some neurodegenerative
       | disease.
        
         | metadat wrote:
         | Yikes, were you okay when you snapped out of it? Glass (and
         | ceramic) shards are remarkably sharp and dangerous.
         | 
         | Ask me how I know..
        
         | PragmaticPulp wrote:
         | These phenomena aren't completely absent in healthy people from
         | time to time.
         | 
         | If it becomes a pattern you should check it out. If it happens
         | from time to time over your life it's not a big deal.
         | 
         | These phenomena are also common in young children as they grow
         | up, too.
         | 
         | > That day I was sleep-deprived (3 hours of sleep on the night
         | before), and had exercised a lot (I'm an athlete).
         | 
         | This is the obvious explanation. I know it likely goes without
         | saying, but 3 hours of sleep is a major risk factor for health
         | problems, including degenerative neurological disease if
         | sustained. If you're experiencing weird sleep/wake relayed
         | symptoms after only sleeping 3 hours, the obvious explanation
         | is sleep deprivation. Don't even consider other explanations
         | until you get back to a healthy sleep habit, which is hopefully
         | soon.
         | 
         | Also, I'm sure you know this, but 3 hours of sleep is going to
         | offset much or perhaps all of the benefit of intense exercise.
         | Skip the gym and get some sleep if you must. It will be a net
         | win.
        
       | PragmaticPulp wrote:
       | It should also be noted that this can be a side effect of some
       | drugs and even supplements. If this happens to you and you're
       | taking medication of any sort, let your doctor sort it out. Don't
       | assume you have a neurodegenerative disease.
        
         | jmckib wrote:
         | It can also be a symptom of withdrawal from alcohol and other
         | drugs.
        
           | titan_twelve wrote:
           | I didn't know about this. Would you be able to link any
           | relevant articles or studies for interested parties?
        
         | andrewl wrote:
         | Do you know what supplements have this as a side effect?
        
           | PragmaticPulp wrote:
           | Supplements in general are very poorly studied relative to
           | prescription drugs. Supplements have also become more
           | powerful in recent years as vendors start producing more
           | potent extracts or even synthesizing what are basically
           | unregulated pharmaceuticals. Some of the supplements on the
           | market in the US are even derived from prescription drugs in
           | other countries which haven't been approved here as
           | medications.
           | 
           | So it's impossible to say. If you start experiencing
           | troubling symptoms, it's wise to discontinue supplements for
           | a while to check if the symptoms persist.
           | 
           | A good rule of thumb is that if it makes you feel energetic
           | or relaxed, there's a high likelihood that it could be
           | associated with sleep disturbance. A lot of the problems
           | coming out of supplement enthusiasts are related to rebound
           | from the supplements when they wear off, so keep that in mind
           | too. What goes up must come down.
        
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