[HN Gopher] Parasite gives wolves what it takes to be pack leaders
       ___________________________________________________________________
        
       Parasite gives wolves what it takes to be pack leaders
        
       Author : gscott
       Score  : 198 points
       Date   : 2022-11-25 09:44 UTC (13 hours ago)
        
 (HTM) web link (www.nature.com)
 (TXT) w3m dump (www.nature.com)
        
       | yayr wrote:
       | > Physical and behavioural changes have also been found in
       | people: testosterone and dopamine production is increased and
       | more risks are taken.
       | 
       | ...
       | 
       | > Up to one-third of humans might be chronically infected.
       | 
       | That is certainly an interesting research vector...
        
       | drooby wrote:
       | Or could it be that wolves that are already more likely to hunt
       | cougars (thus eat them and get the parasite) have high risk
       | taking behavior and are thus more likely to be pack leaders? And
       | the parasite actually has a benign influence on the host?
        
         | trenchgun wrote:
         | Could be, but there are mechanisms which explain how toxoplasma
         | creates the risky bhaviour: by increasing testosterone
         | production.
         | 
         | https://news.ycombinator.com/item?id=33742779
        
       | snshn wrote:
       | Elon Musk is probably full of 'em.
        
       | tgv wrote:
       | I don't see anything in that article that makes the conclusion
       | inevitable. It's a remarkable correlation for sure, but
       | unfortunately it doesn't go beyond that. There's no pathway from
       | infection to leadership (just a vague hypothesis that doesn't
       | resemble the mechanism in rats and hyenas), and it doesn't look
       | as if they looked at uninfected pack leaders. Perhaps pack
       | leaders or strays eat more dead cat, or some other intermediate
       | host of T.gondii. Perhaps they sampled in the wrong time frame.
       | The full article might have more info, but the linked one
       | doesn't.
        
         | nonrandomstring wrote:
         | I haven't read the paper either, but I must say the operation
         | of parasites as elements in complex biological super-systems is
         | absolutely fascinating. Ants that march to the top of trees
         | under the influence of fungus spores trying to be eaten by
         | birds. Fish that commit suicide by swimming toward predators as
         | part of a parasitic lifecycle.... evolution is truly
         | miraculous.
         | 
         | Another apocryphal story is cats carrying Toxoplasma Gondii
         | make some people really like cats. So maybe mad cat lady
         | syndrome is treatable with drugs :)
         | 
         | Who knows what super-systems we are unwittingly a part of. That
         | seems an interesting area for big-data + AI hypothesis
         | synthesis - we may find new explanations or even whole new
         | branches of behaviour in psychology.
        
           | novosel wrote:
           | https://pubmed.ncbi.nlm.nih.gov/31980266/
        
           | pydry wrote:
           | Things also get interesting if you look at economic and
           | social systems in this context.
        
             | thaumasiotes wrote:
             | For sure. Married people barely vote Democratic. Given
             | that, what kind of society will the Democratic Party seek
             | to create?
        
               | pfisch wrote:
               | How do you know you're not just catching cross
               | correlation with age?
        
               | bena wrote:
               | Age, socio-economic status, and other confounding
               | factors.
               | 
               | Not to mention, according to him, 40% is "barely".
        
               | jesushax wrote:
               | He probably didn't have the stat off the top of his head,
               | so it was exaggerated based on assumptions. But the
               | underlying intuition had a kernel of truth and applies to
               | any political party, or any institution, really. For
               | example, if an organization dedicated to the poor mainly
               | draws support from poor people, they have a kind of
               | incentive to subtly maintain poverty.
               | 
               | This theory that institutions kind of have a tendency to
               | perpetuate the conditions that necessitate their
               | existence was developed by Durkheim, and like most of the
               | other early sociologists, I really recommend it over
               | newer stuff. It's not conspiratorial, the idea is that
               | organizations that do this outsurvive groups that
               | legitimately solve the problems they are created to
               | solve, and so through an evolutionary process, the
               | longest lived and deepest institutions tend to be ones
               | with behaviors ironically antithetical to their supposed
               | mission (even if the members of the institution totally
               | believe in and earnestly support the mission).
               | 
               | The typical example (at least when I was into this kind
               | of stuff) is the Catholic Church earnestly helping the
               | poor, but doing so in a way that societaly, will never
               | actually alleviate poverty, or may even exacerbate it.
               | Now days I tend to hear this line of thinking used about
               | liberals supporting policies that "help" minorities but
               | really perpetuate the cycle of poverty.
               | 
               | Whether you believe this is beside the point, I only mean
               | to suggest that OP is wrong, but a steelman of his point
               | is deeper than it seems, and deserves our good faith imo.
        
               | qnr wrote:
               | Same general idea: it's not in the dating apps' best
               | interest to get their users into successful long-term
               | relationships and out of the dating pool.
        
               | bena wrote:
               | thaumasiotes was saying married people vote Republican
               | more often. pfisch was suggesting he was actually
               | witnessing a separate correlation. Older people tend to
               | vote Republican more often, older people are more often
               | married than younger people.
               | 
               | I was suggesting that there are other things that go into
               | even the age issue.
               | 
               | Religious people are more likely to marry than non-
               | religious people. Religious people tend to vote more
               | conservatively than non-religious people. Etc. etc. I was
               | agreeing with pfisch that a lot of the reasons people get
               | married often line up with reasons why people vote
               | Republican.
               | 
               | And I wouldn't say the Catholic Church believes its
               | mission to be to eliminate poverty. Or even alleviate it.
               | They want to temporarily alleviate the superficial
               | effects of poverty on people.
        
               | klipt wrote:
               | Yes you could definitely make an argument that democrats
               | benefit from poverty, or that republicans benefit from
               | illegal immigration. People in poverty receiving benefits
               | vote democrat because they're afraid republicans will cut
               | benefits. People who fear illegal immigrants taking their
               | jobs will vote republican because they think republicans
               | will be tougher on illegal immigration. If democrats
               | actually solved poverty or if republicans actually
               | deported 100% of illegal immigrants, a lot of people
               | would lose their reasons to vote for those parties.
               | 
               | Arguably by the same reasoning, republicans benefit from
               | legal abortion and their finally getting Roe v Wade
               | reversed was terrible for their electoral performance.
        
               | salawat wrote:
               | >Arguably by the same reasoning, republicans benefit from
               | legal abortion and their finally getting Roe v Wade
               | reversed was terrible for their electoral performance.
               | 
               | You aborted your analysis too early. Getting Roe v. Wade
               | overturned still benefits Republicans until such time as
               | Legislation is successfully passed to outlaw abortion at
               | all levels (i.e. State & Federal, though arguably we're
               | talking Republican here, so one would think they'd
               | content themselves with States). Only then would the
               | "problem" be solved.
        
               | jesushax wrote:
               | You are completely correct, I didn't mean to argue
               | against the Dems, just noting that I hear this critique
               | raised against them a lot.
               | 
               | >Arguably by the same reasoning, republicans benefit from
               | legal abortion and their finally getting Roe v Wade
               | reversed was terrible for their electoral performance.
               | 
               | Indeed, the far-right has raised exactly this criticism
               | of overturning Roe v Wade:
               | 
               | >If you have limited energy and a limited number of
               | possible wins, it is important to focus your limited
               | energy on one kind of win: wins that make future wins
               | easier. By definition, these are the kinds of wins that
               | augment your power. These are real wins. > >There is
               | another kind of "win," wins which expend your power in
               | order to achieve some result you want. These are
               | sometimes called "Pyrrhic victories." Pyrrhus took the
               | battlefield, but after the battle his chances of winning
               | were reduced. His tactical "victory" was a strategic
               | defeat.
               | 
               | Source: You can only lose the culture war
               | (https://graymirror.substack.com/p/you-can-only-lose-the-
               | cult...)
               | 
               | This kind of thinking isn't partisan, I think it
               | describes the a problem that occurs with institutions in
               | any society. I'm not sure what the solution is, other
               | than to be collectively vigilant against institutions
               | succumbing to these tendencies. Which seems woefully
               | inadequate.
        
               | thaumasiotes wrote:
               | > Not to mention, according to him, 40% is "barely".
               | 
               | You might want to think about what a 20-point margin
               | means in electoral politics. Taking 60% of the vote is
               | routinely described in terms like "landslide victory".
        
               | shkkmo wrote:
               | Married people make about half the Democratic voter base,
               | so your reasoning seems flawed at best.
               | 
               | Not to mention that a large part of the relative under
               | representation of married people in the Democratic voter
               | base is due to relative over representation of younger
               | people.
        
               | voltaireodactyl wrote:
               | This is a fascinating and unexpected piece of
               | information. I would be very intrigued to read your
               | source.
        
               | thaumasiotes wrote:
               | Here's CNN's exit poll for November 2022:
               | https://www.cnn.com/election/2022/exit-polls/national-
               | result...
               | 
               | Unmarried women vote Democratic, 68-31.
               | 
               | Unmarried men vote Republican, 52-45.
               | 
               | Married women, Republican, 56-42.
               | 
               | Married men, Republican, 59-39.
               | 
               | Here's an image purporting to describe the Reuters-Ipsos
               | poll of 2012: https://i.imgur.com/I3ycNpC.png . (I
               | haven't been able to find the actual poll.) It only gives
               | the Republican share of the vote for each demographic,
               | but Republicans+Democrats should be close to 100% of the
               | vote. 1992 is an exception.
               | 
               | Unmarried women, 31% Republican.
               | 
               | Unmarried men, 41% Republican.
               | 
               | Married women, 55% Republican.
               | 
               | Married men, 58% Republican.
        
               | meindnoch wrote:
               | Most likely Democrat couples don't feel the need to marry
               | at the same rate as Republicans.
               | 
               | Anyhow, the quoted figures doesn't exactly show that
               | married people "barely vote Republican".
        
               | salawat wrote:
               | Sampling bias: those that respond to polls.
        
               | dtgriscom wrote:
               | We went from wolf parasites to "Democrats want to prevent
               | marriage", via exaggerated polling data. How does this
               | add to our conversation?
        
               | tafda wrote:
               | " Republicans lead among married men (51%-38%), while
               | married women are evenly divided (44% Republican, 44%
               | Democratic). "
               | https://www.pewresearch.org/politics/2015/04/07/a-deep-
               | dive-...
               | 
               | That's out of more than 60 million married couples in the
               | US. Barely here equals about half?
        
               | thaumasiotes wrote:
               | > Barely here equals about half?
               | 
               | Well, first, married women are not evenly divided. They
               | are more Republican and less Democratic than unmarried
               | men, who are also Republican.
               | 
               | Second, even by the numbers you cite, Democrats aren't
               | coming close to half of the vote among married couples.
               | 
               | Third, you have over 11% of the vote going to third
               | parties. In reality, in 2016 the two-party vote share was
               | just over 94%.
               | 
               | Some of these problems seem to arise from you confusing
               | party affiliation with voting. They're different.
        
         | freeflight wrote:
         | _> Perhaps they sampled in the wrong time frame. The full
         | article might have more info, but the linked one doesn 't._
         | 
         | The data was collected over nearly 27 years, the link to the
         | full open access paper is in the references;
         | https://doi.org/10.1038%2Fs42003-022-04122-0
        
         | simonh wrote:
         | They looked at animals that were and were not infected,
         | throughout their lives, and saw what they did, so they knew
         | whether the animals were infected or not before they became
         | pack leaders. From the article:
         | 
         | >The team looked at 256 blood samples from 229 wolves, which
         | had been carefully watched throughout their lives, and had
         | their life histories and social status recorded. Meyer and
         | Cassidy found that infected wolves were 11 times more likely
         | than uninfected ones to leave their birth family to start a new
         | pack, and 46 times more likely to become pack leaders -- often
         | the only wolves in the pack that breed.
        
           | fergal_reid wrote:
           | Havent read the paper, but your quote doesn't change the core
           | point that it could be correlation.
           | 
           | E.g. perhaps aggression makes them more likely to eat
           | infected animals and also more likely to challenge for
           | leadership.
        
             | Mistletoe wrote:
             | I had this thought but doesn't the pack mostly eat the same
             | thing?
        
               | brohee wrote:
               | Not those that set out on their own, and thus are more
               | likely to catch rodent while alone than feasting on big
               | prey with the pack...
               | 
               | Unless they can pinpoint the infection and a subsequent
               | behavior change, it's not super conclusive.
               | 
               | It's like concluding catching an IST makes you more
               | promiscuous, even if that would likely be supported by
               | statistics...
        
       | stared wrote:
       | Potetnially related: "Men Who Owned Cats As Kids May Have Higher
       | Psychosis Risk" https://www.iflscience.com/men-who-owned-cats-as-
       | kids-may-ha...
        
         | msrenee wrote:
         | That article uses psychosis and schizophrenia interchangeably.
         | There's also no mention of the familial nature of
         | schizophrenia. There's a genetic link in many cases and there's
         | been work in that area that's starting to identify particular
         | genes that are associated with the disorder.
         | 
         | It could be that infection with T. gondii is sometimes the
         | difference between simply having a predisposition towards
         | schizophrenia and actually developing the symptoms. Pot use in
         | the late teens and early 20s can have the same effect. It
         | doesn't cause schizophrenia, but it may be a trigger than leads
         | a genetically predisposed individual to develop the disorder.
        
       | c3534l wrote:
       | How do we know that risk-taking doesn't lead to a higher rates of
       | parasitic infection?
        
       | manv1 wrote:
       | Pussy changes everything?
        
         | californiadreem wrote:
         | Squeaky meal gets the grease.
        
       | jokoon wrote:
       | I'm still not very convinced of the scientific definition of
       | "pack leader".
       | 
       | Behavior science is sensitive to interpretation, in my view.
       | 
       | It's a human bias to see human concepts in other species.
        
         | jonplackett wrote:
         | What do you mean by that? I thought it was a pretty
         | accepted/normal thing for wolves to have a pack leader?
        
           | goodpoint wrote:
           | https://phys.org/news/2021-04-wolf-dont-alpha-males-
           | females....
           | 
           | https://wolf.org/headlines/44265/
        
             | goodpoint wrote:
             | And why the silent downvotes?
        
       | Communitivity wrote:
       | The research results are an interesting find and good work. They
       | indicate a clear need for more research. They aren't conclusive
       | as is, at least with the limited info I found (I haven't found a
       | papers archive from The Wolf Society 2022 conference, so I had to
       | go by press articles). Sample size of 229 seems small,
       | considering the diversity among wolf packs. For example, were
       | these wolves from one state vs multiple states. Getting a larger
       | sample size would be hard but not impossible if the study lasted
       | a long time. Science is about building a stairway - 99% steps 1%
       | momentous landings that built on all the steps before them. This
       | work is a good solid step.
        
         | pvaldes wrote:
         | Yep, who would imagine that animals in societies tend to
         | discriminate against the ill and diseased.
        
       | codexjourneys wrote:
       | Bringing my comments over from the other submission:
       | 
       | Not just wolves. Toxoplasma infection also "may make people look
       | more attractive to the opposite sex":
       | https://www.earth.com/news/parasite-makes-infected-people-lo...
       | 
       | Is this because it increases risk-taking behavior? Who knows, but
       | it's interesting that something with potentially significant
       | health drawbacks may have enough benefits that it's evolved to
       | coexist with us (up to 50% of people carry it).
       | 
       | Overall, it looks increasingly like microbes shape our behavior
       | and emotional health:
       | https://www.science.org/content/article/evidence-mounts-gut-...
        
         | [deleted]
        
       | jjtheblunt wrote:
       | it would be fascinating to see a plot of toxoplasma gondii
       | hitting the first page of HN vs time.
       | 
       | It seems periodic, and i'm not kidding. (kinda like Jodi Foster
       | in Contact with the headphones on)
       | 
       | Not this time, but usually it's a revelation about the protozoan
       | with mice being fearless around cats, or about humans living with
       | cats, with associated proposals of drama, perhaps to drive
       | pageviews.
        
       | Trouble_007 wrote:
       | Also; Grey wolves infected with this parasite are more likely to
       | become pack leaders :
       | https://news.ycombinator.com/item?id=33738581
        
         | the_af wrote:
         | It's the same news, reported in two different places.
        
           | Trouble_007 wrote:
           | I reiterate;
           | 
           | Toxoplasma gondii :
           | https://en.wikipedia.org/wiki/Toxoplasma_gondii
           | 
           | Risk factors for human infection : https://en.wikipedia.org/w
           | iki/Toxoplasma_gondii#Immune_respo...
        
             | the_af wrote:
             | Before, you linked to another article about wolves which
             | was basically the same article that is linked at the top of
             | this thread.
             | 
             | So "also, Grey Wolves" -- the "also" is redundant, since
             | it's about the same wolves both times, and the finding is
             | the same.
        
       | helsinkiandrew wrote:
       | > Cassidy found that infected wolves were 11 times more likely
       | than uninfected ones to leave their birth family to start a new
       | pack, and 46 times more likely to become pack leaders
       | 
       | I thought we now believe that wolf packs are purely family units
       | - mother, father and their cubs. There's no alpha wolves leading
       | a pack of other male and female wolves, just stray wolves and
       | family units. So a wolf pack is only comprised of the leader and
       | its cubs.
       | 
       | https://wolf.org/wolf-info/wild-kids/wolf-families
        
         | henrydark wrote:
         | I don't k ow anything about wolves or parasites, but those two
         | things don't contradict each other. Maybe wolves with the
         | parasite are exactly more likely to form such a family unit
        
           | helsinkiandrew wrote:
           | Perhaps its just bad wording and they mean "they are 11 times
           | more likely than uninfected ones to leave their birth family
           | (BUT don't necessarily start a new pack), and 46 times more
           | likely to (create a pack and) become pack leaders.
        
         | stared wrote:
         | It is how I read that. They start their faimilies. Alpha
         | male/female = parents. A pack is their extended family.
        
         | Alan_Dillman wrote:
         | Sure, but there has to be stray wolves forming new packs. Every
         | pack in existence started that way. While there is no fight for
         | who will be "The Alpha", obviously there is a patriarch and
         | matriarch of the pack.
        
       | Kiboneu wrote:
       | It's impressive to see T. Gondii evolve to influence their hosts
       | to write positive PR.
       | 
       | Joking aside, it makes sense to me that higher risk behavior on
       | the host's part would increase a parasite's spread, since some of
       | the energy that drives risk also increases the rate of physical
       | interaction with the world; like a free roaming particle with a
       | lot of momentum on a substrate. It is good to see more research
       | looking into this since this seems to be low hanging fruit
       | compared to possible compound effects of t. gondii influence on
       | society.
        
         | psychphysic wrote:
         | Ha!
         | 
         | It's good research but there is a major caveat I didn't see it
         | in this press release.
         | 
         | Before they answer questions like yours they need to have
         | tracked when infection occured.
         | 
         | Simple conundrum are wolves who are infected with t. Gondii
         | more likely to leave their pack? Or are wolves that leave their
         | pack more likely to get infected?
         | 
         | Similarly for pack leaders. It might seem obtuse to ask for
         | this but it is important to disentangle somewhat cause and
         | correlation.
         | 
         | In humans it's theorised to increase risk of car accidents
         | (based on a french study monitoring speeding and traffic rule
         | obedience).
        
           | periheli0n wrote:
           | Why do press releases always have to oversell the findings? I
           | think it plays into the hands of science deniers.
           | 
           | I can see how press departments could claim that they're only
           | doing their job, but it's potentially unethical and
           | dangerous.
        
           | ShamelessC wrote:
           | Probably a good idea to critique the paper, not the press
           | release. I haven't read it but for all you know they could
           | have discussed this at length.
        
             | sigmoid10 wrote:
             | They discuss it briefly and it turns out the above
             | commenter is 100% correct in his assessment. Relevant quote
             | from the paper:
             | 
             | >Given the correlational nature of the study, observed
             | patterns may not be causal; for example, higher risk-takers
             | could be more likely to be both entrepreneurial and exposed
             | to T. gondii [...], thereby driving the correlation.
             | 
             | Remember that while it might sound amazing that a parasite
             | could steer higher cognitive functions towards something as
             | abstract as being more entrepreneurial, there is no
             | practicable mechanism suggested so far and until someone
             | figures out if it is even possible, all these studies are
             | to be handled with care.
        
               | ShamelessC wrote:
               | My point remains - thank you for following up with what
               | appears to be a proper criticism.
        
               | Kiboneu wrote:
               | > there is no practicable mechanism suggested so far
               | 
               | There is, actually. T. Gondii has the genes to make
               | tyrosine hydroxylase which is a dopamine precursor. It
               | also visibly modifies rodent behavior around cat urine.
               | Robert Sapolsky is one of many researchers narrowing in a
               | mechanistic model of how parasites can influence host
               | behavior.
               | 
               | https://pubmed.ncbi.nlm.nih.gov/17404235/
               | https://www.edge.org/conversation/robert_sapolsky-toxo
               | 
               | Edit:
               | 
               | Steering higher-order behavior by modifying reward
               | circuits is possible and overtly practiced in many types
               | of (mostly superficial) human relationships,
               | organizational interfaces and societal structures.
        
       | nahuel0x wrote:
       | If a parasite gives the host a competitive advantage, is really a
       | parasite?
        
       | Kognito wrote:
       | "Semi-dormant tissue cysts form in the brain, eyes and heart
       | muscle, persisting the infection for life"
       | 
       | "Can also infect humans"
       | 
       | Well that doesn't give me nightmares at all.
        
         | sva_ wrote:
         | > In the United States it is estimated that 11% of the
         | population 6 years and older have been infected with
         | Toxoplasma. In various places throughout the world, it has been
         | shown that more than 60% of some populations have been infected
         | with Toxoplasma.
         | 
         | https://www.cdc.gov/parasites/toxoplasmosis/epi.html
        
       | parhamn wrote:
       | I really don't get T. Gondii. I read all these article about how
       | it might be affecting us, a source of mental health disorders, so
       | on and so on. And it is very common in household cats + a lot of
       | people already have it. CDC says, "While the parasite is found
       | throughout the world, more than 40 million people in the United
       | States may be infected with the Toxoplasma parasite." I assume
       | present tense means currently infected?
       | 
       | Genuinely curious, why aren't we doing an annual anti-parasitic
       | or something given the drugs are relatively benign?
        
       | tehchromic wrote:
       | I had heard the relationship between countries with better
       | football teams having higher rates of t gondii, now it all makes
       | sense
        
       | bof_ wrote:
       | Tell me about it.
        
       | deafpolygon wrote:
       | So.. Chad parasites.
       | 
       | I'm off to find a parasite, wish me luck.
        
       | majkinetor wrote:
       | Fucking amazing...
       | 
       | How does it know what gene to promote? Its hard to beleive that
       | such "primitive" organizm promotes exploration and risky behavior
       | in number of different animals.
        
       | nix23 wrote:
       | Can we please do the same study with politicians?
        
         | msrenee wrote:
         | I think you're being facetious, but that would actually be an
         | interesting segment of the population to look at for prevalence
         | of T. gondii. I'd really like to see that study.
        
           | nix23 wrote:
           | Well no, it's was kind of a real question..but also with "the
           | elon's of the world"
        
       | pvaldes wrote:
       | Parasitized wolves (omegas being forced to eat the rotten
       | leftovers) are losers that are often chased off the pack.
       | 
       | And most of them die for that.
       | 
       | Two titles. Same article; just without the starry-eyed
       | documentary lens
        
       | hellfish wrote:
       | > Up to one-third of humans might be chronically infected.
       | 
       | > Infections with toxoplasmosis are associated with a variety of
       | neuropsychiatric and behavioral conditions
       | 
       | > Research on human vaccines is ongoing.
       | 
       | I say 5 years before we have a moral panic about this
        
       | nathan_compton wrote:
       | Can't wait till pickup artist types are infecting themselves on
       | purpose so they can be more alpha.
        
         | BlueTemplar wrote:
         | > possibly even increasing their chances of encountering
         | cougars and exposing more members to infection
         | 
         | (I'll get my coat.)
        
         | [deleted]
        
       | Invictus0 wrote:
       | Was this entire comment section generated by GPT-3?
        
       | ChrisMarshallNY wrote:
       | _> Up to one-third of humans might be chronically infected._
       | 
       | That explains so much...
        
       | FirstLvR wrote:
       | This whole post and comments are just incredible ... can we
       | predict one society success purely on parasite composition?
        
       | [deleted]
        
       | meindnoch wrote:
       | "Risky business: linking Toxoplasma gondii infection and
       | entrepreneurship behaviours across individuals and countries"
       | (https://pubmed.ncbi.nlm.nih.gov/30051870/)
       | 
       | >Among professionals attending entrepreneurship events, T.
       | gondii-positive individuals were 1.8x more likely to have started
       | their own business compared with other attendees (n = 197).
       | Finally, after synthesizing and combining country-level databases
       | on T. gondii infection from the past 25 years with the Global
       | Entrepreneurship Monitor of entrepreneurial activity, we found
       | that infection prevalence was a consistent, positive predictor of
       | entrepreneurial activity and intentions at the national scale,
       | regardless of whether previously identified economic covariates
       | were included.
       | 
       | "The association of latent toxoplasmosis and level of serum
       | testosterone in humans"
       | (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994116/)
       | 
       | >Comparison of testosterone concentrations and control groups
       | showed that testosterone concentration in study group was higher
       | than that in control group with statistically significant
       | difference.
       | 
       | "Toxoplasma gondii infection enhances testicular steroidogenesis
       | in rats"
       | (https://onlinelibrary.wiley.com/doi/abs/10.1111/mec.12042)
       | 
       | >Testosterone, a testicular steroid, is known to reduce fear and
       | enhance sexual attractiveness in males. Here, we show that
       | Toxoplasma gondii infection enhances expression of genes involved
       | in facilitating synthesis of testosterone, resulting in greater
       | testicular testosterone production in male rats.
        
         | frontman1988 wrote:
         | 2 billion people already have the Toxoplasma gondii in their
         | brains. If it were to affect humanity is some profound way, we
         | would have already linked it to something more substantial than
         | n=197 studies of correlating success in entrepreneurship to the
         | virus.
        
           | TheBigSalad wrote:
           | Good point. We should stop studying it because we should have
           | known by now.
        
           | wpietri wrote:
           | That's a pretty bold take from somebody who thinks it's a
           | virus and not a single-celled parasite. But then as Charles
           | Darwin said, "ignorance more frequently begets confidence
           | than does knowledge."
        
           | ajmurmann wrote:
           | There are other studies that link Toxoplasmosis to increased
           | risk taking. Here one on increased likelihood of getting into
           | car accidents: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1
           | 17239/#__ffn_s....
           | 
           | It's widely known for many years now. Twenty years ago there
           | was a huge report about it on German public radio. The
           | article I looked references research from the seventies.
           | 
           | It's been a strange philosophical point to me that catching a
           | parasite that really wants to be in your cat can alter your
           | personality and unless you are a pregnant woman the medical
           | system ignores it.
        
             | msrenee wrote:
             | What's the medical system going to do about a parasite that
             | often doesn't cause any symptoms that can pinpoint the
             | particular pathogen? Most healthy people clear the
             | infection without ever knowing anything happened.
             | 
             | We don't have any way to undo whatever the parasite did
             | while it was active. It's probably possible to create a
             | vaccine, but the full impact in humans is still being
             | explored and a vaccine for a pathogen that's been with us
             | mostly unnoticed since cats have been with us isn't a high
             | priority.
             | 
             | I'd also say decades of research into the effects of T.
             | gondii is explicitly not the medical system ignoring it.
             | It's the medical system being aware of it, but there aren't
             | any great solutions at this point.
             | 
             | I'd also like to point out the difference between difficult
             | to define risk-taking behavior in adults vs. miscarriage,
             | blindness, neurological issues, and hydrocephalus among
             | other risks to a fetus.
        
               | ajmurmann wrote:
               | I definitely don't have a clear answer here either. It's
               | just a interesting thing to think about. It's very common
               | and can change you or your loved ones personality.
               | However, reviving it of course would also changed your
               | personality. I've noticed recently that I've gotten much
               | more risk-averse than I used to be and think it might be
               | bad. Maybe I should get toxoplasmosis on purpose? Really
               | creates a lot of questions about "self".
        
               | msrenee wrote:
               | If T. gondii has you questioning the existence of free
               | will, you should (or maybe shouldn't) look into how your
               | gut microbiota affect your mental processes. We're less
               | individuals and more systems of millions of different
               | critters.
        
               | ajmurmann wrote:
               | Thanks! I've already down that and many similar rabbit
               | holes and am entirely puzzled about self, sentients and
               | existence :)
        
           | enkid wrote:
           | That's not how science works.
        
           | jjallen wrote:
           | This may very well be true. I wish you had posted more of a
           | direct criticism of the study in question other than its
           | small sample size.
           | 
           | It may have had a similar control group and could be
           | relevant. It could be that individuals with more of the
           | parasite are more likely to become entrepreneurs still.
        
         | eloff wrote:
         | I can see the headlines now "you won't believe this one weird
         | trick for bigger gains and better performance in bed".
        
           | Silverback_VII wrote:
           | What is the legal framework for a product that infects people
           | with "beneficial" parasites ?
        
             | gumby wrote:
             | Ever seen "probiotics" for sale at the shops? Or live
             | culture yoghurt?
        
             | [deleted]
        
             | hanniabu wrote:
             | Just call it a supplement and you can do anything
        
             | escapecharacter wrote:
             | As long as it doesn't affect my essential fluids, I'm game
        
               | brookst wrote:
               | Just take it with pure rain water and you'll be fine.
        
               | brohee wrote:
               | Maybe read
               | https://en.wikipedia.org/wiki/Parasite_%28Grant_novel%29
               | first...
        
           | marginalia_nu wrote:
           | In a world where people are supplementing with
           | turkesterone... It's an arthropod moulting hormone-analogue.
           | But it's an ecdy _steroid_. So surely its ergogenic.
           | 
           | Sure, why not.
        
       | rainmaker124 wrote:
        
       | machina_ex_deus wrote:
       | Imagine how dystopian that would sound in humans, like some
       | science fiction horror.
       | 
       | "All the leaders are secretly infected by parasites".
       | 
       | Sounds like interesting sci fi movie premise.
        
         | yesbut wrote:
         | There is the idea that anyone that wants to be a leader
         | probably shouldn't be a leader. These are the types of people
         | who crave being in positions of authority over others. They'll
         | step on anyone they need to in order to get the the top. They
         | might be the leader, but they usually aren't necessarily the
         | types of people that are looking out for the best interests of
         | the people they lead.
        
           | TEP_Kim_Il_Sung wrote:
           | There's also the Dunning-Kruger Effect; Incompetent or dumb
           | people don't recognize their own failings and assume they are
           | geniuses. Smart and competent people know their own
           | deficiencies and assume they're limited or dumb.
        
             | Rallen89 wrote:
             | so if you feel like you are limited/dumb are you actually
             | smart or does realising that loop back to you actually
             | really being dumb. seems like a catch 22
        
               | wpietri wrote:
               | With DK, the underlying model is that people only improve
               | when they see their flaws. People who are very good at
               | seeing their own flaws improve their performance, but
               | tend to think they are doing worse than they are.
               | 
               | In my view whether or not that makes you "smart" or
               | "dumb" depends on what you do with the insight. As Ira
               | Glass writes: "Nobody tells this to people who are
               | beginners, I wish someone told me. All of us who do
               | creative work, we get into it because we have good taste.
               | But there is this gap. For the first couple years you
               | make stuff, it's just not that good. It's trying to be
               | good, it has potential, but it's not. But your taste, the
               | thing that got you into the game, is still killer. And
               | your taste is why your work disappoints you. A lot of
               | people never get past this phase, they quit. Most people
               | I know who do interesting, creative work went through
               | years of this. We know our work doesn't have this special
               | thing that we want it to have. We all go through this.
               | And if you are just starting out or you are still in this
               | phase, you gotta know its normal and the most important
               | thing you can do is do a lot of work. Put yourself on a
               | deadline so that every week you will finish one story. It
               | is only by going through a volume of work that you will
               | close that gap, and your work will be as good as your
               | ambitions. And I took longer to figure out how to do this
               | than anyone I've ever met. It's gonna take awhile. It's
               | normal to take awhile. You've just gotta fight your way
               | through."
        
           | stncls wrote:
           | I was once part of a department that was so well-managed and
           | functional that I couldn't quite believe it. Then when time
           | came choose a new department head, someone told me that they
           | had always specifically avoided people who _wanted_ to lead
           | the department for the job.
        
             | yesbut wrote:
             | Good policy. In worker owned enterprises that are run
             | democratically the owner/employees elect their managers
             | from the ranks. They act as manager for a term and then go
             | back to their original position after the next election.
             | Keeps everyone based in reality.
        
               | bsenftner wrote:
               | Decades ago, the Boston University Free Press (the
               | alternative views newspaper) was managed in this manner.
               | My buddy ended up running the paper for a year because he
               | was the least political, most liked guy working at the
               | place. He just wanted people to be happy. After a year,
               | he was no longer happy and was glad to give up the job.
        
               | yesbut wrote:
               | Managers, like politicians, should have term limits. The
               | temptation for abuse and favoritism is too strong.
        
               | msrenee wrote:
               | I agree with you for the most part, but what happens when
               | you've got a damn good manager? They exist for sure.
               | They're just unfortunately a minority.
        
             | victor106 wrote:
             | My simple mind thinks:-
             | 
             | Why would you want someone who does not want to do a job do
             | that job?
             | 
             | If you are interviewing someone and that person said "I
             | don't want to do this job" would you hire that person?
        
               | salawat wrote:
               | There's a difference between "I don't want to do this
               | job", and "I don't want to do this job, but it needs to
               | be done, and apparently everyone else thinks I'm the best
               | fit for it. As much as I now hate you all, I'll do it,
               | and may God have mercy on your souls."
               | 
               | I've been told several times that I become scarily
               | competent at anything I hate, far in excess of those
               | things that make me happy or bring me joy.
               | 
               | I guess what I'm trying to say is, don't discount disgust
               | or aversion to something or it's lack as a
               | disqualification to manage that thing. Quite to the
               | contrary, they may be just the person aware enough of the
               | thing in question to reliably manage it. I'll take a
               | candidate who can explain at length why they hate that
               | job over the most eager "this'll be great" candidate
               | ever.
               | 
               | I'll just be realistic about my assessment of their
               | tenure, and the compensation offered, and try really hard
               | to figure out what they actually want before pulling the
               | trigger on the hire.
        
             | Eddy_Viscosity2 wrote:
             | "Anyone who is capable of getting themselves made President
             | should on no account be allowed to do the job." - Douglas
             | Adams
        
             | beardyw wrote:
             | A perfect model for democracy I would say.
        
               | Jenk wrote:
               | The flaw is that it forces someone into a role they do
               | not want to fulfil, that could see the occupant become
               | resentful of those around them and act out of spite.
               | 
               | The short answer is there is no perfect model, people
               | will always be people.
        
               | soco wrote:
               | I somehow expect that person wouldn't have become
               | spiteful _just_ because of the election, so wouldn't get
               | elected in the first place... but yeah, we only have bad
               | or worse solutions.
        
               | dasv wrote:
               | An idea that goes back to Plato's republic.
        
           | acuozzo wrote:
           | > There is the idea that anyone that wants to be a leader
           | probably shouldn't be a leader. These are the types of people
           | who crave being in positions of authority over others.
           | 
           | Which is why it's helpful to have as many (what I refer to
           | as...) "power traps" in a society as possible: coaching,
           | teaching, leading an HOA, leading a PTA, etc.
           | 
           | I have nothing against these endeavors, you must understand,
           | but my view is that a person spending time acting as a judge
           | for a dog show is less likely to pursue becoming an actual
           | judge.
        
             | yesbut wrote:
             | Solution: Put term limits on democratically elected Dog
             | Show judges, as well as normal judges.
        
               | [deleted]
        
           | tomger wrote:
           | I think that's the takeaway from the Lord of the Rings.
        
         | [deleted]
        
         | californiadreem wrote:
         | "There's a secret cabal of beings that are making my life
         | personally miserable" is already a common enough position that
         | cyclically occurs in human history every hundred years or so
         | that I don't think it's a fiction. I don't think it's an
         | untenable premise to suspect that toxoplasmosis pandemics are
         | cyclically-occuring in humans already and are responsible for
         | revolutionary periods and/or imperialism.
         | 
         | What people might find unpalatable is the idea that parasitic
         | infection could determine so fundamentally political beliefs
         | and ideology, but consider that the idea of not cleaning your
         | hands directly led to disease was considered literal insanity
         | (see the tragic history of Ignaz Semmelweis) prior to germ
         | theory. Sometimes it's the smallest catalysts that cause the
         | largest changes. For the want of a nail...
        
           | hindsightbias wrote:
           | "Cats began their unique relationship with humans 10,000 to
           | 12,000 years ago in the Fertile Crescent, the geographic
           | region where some of the earliest developments in human
           | civilization occurred "
           | 
           | Correlation or causation?
        
             | treis wrote:
             | Surely causation. Farmers store crops which attract rodents
             | which attract felines. Wild cats that mind their manners do
             | better in this environment. Eventually wild cats become the
             | kitty cats we know today.
        
               | wpietri wrote:
               | I think they were suggesting that causality could run the
               | other way.
        
               | shkkmo wrote:
               | That wild cats infected humans so that humans would
               | develope agriculture that would attract rodents for the
               | cats to eat? That hypothesis doesn't seem very
               | plausible...
        
               | wpietri wrote:
               | That civilization bootstrapped due to brain chemistry
               | changes via human/cat association.
        
               | klipt wrote:
               | This catspiracy goes all the way to the top!
        
           | californiadreem wrote:
           | The Article:
           | 
           | > Wolves infected with a common parasite are more likely than
           | uninfected animals to lead a pack, according to an analysis
           | of more than 200 North American wolves1. _Infected animals
           | are also more likely to leave their home packs and strike out
           | on their own._
           | 
           | From Wikipedia, Toxoplasmosis Gondii (
           | https://en.wikipedia.org/wiki/Toxoplasma_gondii ):
           | 
           | > Although under-studied, penguin populations, especially
           | those that share an environment with the human population,
           | are at-risk due to parasite infections, mainly Toxoplasmosis
           | gondii. The main subspecies of penguins found to be infected
           | by T. gondii include wild Magellanic and Galapagos penguins,
           | as well as blue and African penguins in captivity.[78] In one
           | study, 57 (43.2%) of 132 serum samples of Magellanic penguins
           | were found to have T. gondii. The island that the penguin is
           | located, Magdalena Island, is known to have no cat
           | populations, but a very frequent human population, indicating
           | the possibility of transmission.
           | 
           | From Werner Herzog's Encounters at the End of the Earth (
           | https://www.youtube.com/watch?v=x7kdDeGXUjI ):
           | HERZOG: Dr. Ainley, is there such thing as insanity among
           | penguins? I try to        avoid the definition of insanity or
           | derangement. I don't mean that a penguin       might believe
           | he or she is Lenin or Napoleon Bonaparte, but could they just
           | go        crazy because they've had enough of their colony?
           | AINLEY: Well, I've never seen a penguin bashing its head
           | against a rock. They        do get disoriented. They end up
           | in places they shouldn't be, a long way from        the
           | ocean.            HERZOG: These penguins are all heading to
           | the open water to the right.       But one of them caught our
           | eye, the one in the center.       He would neither go towards
           | the feeding grounds at the edge of the ice,       nor return
           | to the colony. Shortly afterwards, we saw him heading
           | straight        towards the mountains, some 70 kilometers
           | away. Dr. Ainley explained       that even if he caught him
           | and brought him back to the colony, he would
           | immediately head right back for the mountains. But why?
           | One of these disoriented, or deranged, penguins showed up at
           | the New Harbor        diving camp, already some 80 kilometers
           | away from where it should be.              The rules for the
           | humans are do not disturb or hold up the penguin. Stand still
           | and let him go on his way. And here, he's heading off into
           | the interior of the        vast continent.            With 5,
           | 000 kilometers ahead of him, he's heading towards certain
           | death.
        
           | thaumasiotes wrote:
           | > consider that the idea of not cleaning your hands directly
           | led to disease was considered literal insanity (see the
           | tragic history of Ignaz Semmelweis) prior to germ theory
           | 
           | I was under the impression that it wasn't so much that people
           | considered the idea insane, as that they hated Semmelweis and
           | were therefore strenuously opposed to anything associated
           | with him.
        
         | lzooz wrote:
         | They generally have something in common that makes them
         | parasites. But it's sort of a sensitive issue now.
        
           | _def wrote:
           | It probably was sensitive forever - that's why it needs to
           | change by speaking about it ;)
        
         | trenchgun wrote:
         | Well... https://news.ycombinator.com/item?id=33742779
        
         | yarg wrote:
         | Animorphs.
        
         | adastra22 wrote:
         | Then whatever you do, don't google "toxoplasma gondii"
        
         | nkzd wrote:
         | There is an anime with a similar theme. Parasyte: The Maxim.
        
         | throwaway71271 wrote:
         | Well most of the leaders of the world today are psychopathic,
         | so its not that far off.
        
         | amarant wrote:
         | Futurama made an episode kinda like this. But it's not so
         | dystopic: if anything it kinda made me want to eat an egg salad
         | sandwich from a vendomat in the bathroom of a truck stop!
        
           | klenwell wrote:
           | Glad you mentioned this. Not horror, comedy!
           | 
           |  _Listen, you! I was born here. I raised a cloud of children
           | here. My ancestors came over here on the sandwich._
           | 
           | One of my favorite episodes.
        
         | wazoox wrote:
         | People engaging in dangerous behaviour (fast-driving
         | motorcycles, sky-diving and... entrepreneurship) are more prone
         | to be infected with toxoplasma.
         | 
         | https://pubmed.ncbi.nlm.nih.gov/31980266/
        
         | s3000 wrote:
         | Culture can be seen as a symbiont for humans. Without
         | infection, we are mere hunter-gatherers.
        
           | the_af wrote:
           | Culture is emergent behavior or a description of human
           | behavior, it's not an external agent that becomes attached to
           | humans, so the analogy really doesn't work.
        
             | upsidesinclude wrote:
             | Hint: check on synonyms for culture
        
               | the_af wrote:
               | Care to elaborate?
        
             | sammalloy wrote:
             | Culture is literally an external agent passed on by our
             | family, friends, peers, institutions, companies, and
             | organizations. It is and always has been a meme. The
             | analogy is sound.
        
               | the_af wrote:
               | It's not an external agent, it's an emergent property of
               | humankind. I don't find memes a compelling idea, but
               | regardless, memes are not viruses and culture is neither
               | a virus nor a virus-like external agent.
               | 
               | So the analogy is very forced and doesn't really work.
        
           | doodledo32 wrote:
           | culture is the greatest egregore and the enemy of progress if
           | not aligned properly
           | 
           | edit: and as the one below me already alluded to, your
           | statement exists on a physical substrate whilst culture
           | exists abstractly thus invalid
        
         | fatneckbeardz wrote:
         | literally an episode of Star Trek TNG, episode title
         | Conspiracy, season 1 episode 24
        
         | yyyk wrote:
         | >Sounds like interesting sci fi movie premise.
         | 
         | Well, their field of work is called poly-ticks...
        
         | mantas wrote:
         | You don't need science finction. Just on following on some
         | online communities:
         | 
         | > :s/reptiloids/parasites/g
        
         | tomjuggler wrote:
         | With one third of humans infected it's more like the plot of an
         | upcoming documentary..
        
           | BlueTemplar wrote:
           | Now I understand the purpose of trigger warnings...
        
           | cruano wrote:
           | > testosterone and dopamine production is increased
           | 
           | Or advertisement
        
       | winReInstall wrote:
       | Syphillis makes you artistically brilliant, gondi makes you
       | fearless, never felt so good, then just before exitus.
       | 
       | So, in conclusion, if the vector has requirements, the infection
       | will try to make the host capable of fullfilment.
       | 
       | If the infection needs sugar, the mitochondria, will make the
       | amobea crawl to algea.
        
         | shubb wrote:
         | Thank you for the final line, I never realised that
        
           | winReInstall wrote:
           | Its all just thesis, nothing is proven yet.
        
             | wongarsu wrote:
             | Obviously it doesn't always happen, a cold doesn't make you
             | more sociable. On the other hand a cold virus that managed
             | to pull that off through some freak mutation would easily
             | outcompete all other variants.
             | 
             | Mitochondria are a bit special in that it's mutually
             | beneficial, but the same could be said about the above cold
             | virus, if the other symptoms are mild enough.
        
               | winReInstall wrote:
               | Urge to travel with corona intensifies.
        
         | arein3 wrote:
         | If 30-50% of people have toxoplasma gondii, "gondi makes you
         | fearless, never felt so good, then just before exitus" sounds
         | like a exaggeration, because I doubt 50% are fearless, never
         | felt so good.
        
       | LightG wrote:
       | The next crop of YC applicants should be interesting ...
        
       | 988747 wrote:
       | And I always thought that wolves live in families, not packs, and
       | what it takes to be a "pack leader" is being the father of other
       | wolves.
        
         | sethammons wrote:
         | I mentioned the article title to my high school animal
         | enthusiast and that is the first thing they said; haven't
         | researched it yet but it seems like these scientists would be
         | "in the know."
        
         | the_af wrote:
         | I had the same thought. And also, the whole classification of
         | "alpha male", "beta male" of the pack has been debunked, since
         | there's no pack, just the wolves family. So the "betas" are
         | actually the young adults of the family, and the "alphas" the
         | father and mother.
        
       | IngvarLynn wrote:
       | Reminds me stories about school of fish following robot:
       | https://newatlas.com/robofish-leeds-univiersity/15588/ or
       | lobotomized fish (this looks more like anecdote than real
       | research, i could not find the source).
       | 
       | Perhaps it is impossible to distinguish stupid boldness from real
       | vision without complex communication.
        
       | 752963e64 wrote:
        
       | Frummy wrote:
       | Where can I buy infected cat feces?
       | 
       | Maybe when aliens visit us they will say, no, step aside humans,
       | we are here to talk to the true leaders of the planet. Bring out
       | your microscopes.
        
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       (page generated 2022-11-25 23:01 UTC)