[HN Gopher] Study first to link weed killer Roundup to convulsio...
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       Study first to link weed killer Roundup to convulsions in animals
        
       Author : pseudolus
       Score  : 231 points
       Date   : 2022-08-23 13:00 UTC (10 hours ago)
        
 (HTM) web link (phys.org)
 (TXT) w3m dump (phys.org)
        
       | crmd wrote:
       | > "A significant finding from our study reveals that just 0.002
       | percent glyphosate, a difference of about 300 times less
       | herbicide than the lowest concentration recommended for consumer
       | use, had concerning effects on the nervous system."
       | 
       | Many toxicity studies feed animals millions of times more of the
       | substance than a human would ever be exposed to, in order to
       | produce a result. This is not the case here. Also, it seems to
       | target the GABA-A receptor, which is pretty stable across
       | species.
        
         | jjtheblunt wrote:
        
         | brutusborn wrote:
         | 300 times is definitely worrying, but it still seems higher
         | than people would be exposed to. Surely after degradation of
         | the chemical on surfaces, water flushing plants and dilution
         | when ingested, humans would never be exposed to a concentration
         | that high.
         | 
         | The highest levels recorded in people in the US is ~2 ug/L [0].
         | It's probable that it still affects GABA receptors at this
         | level but I'm hoping it has negligible effects.
         | 
         | [0] https://www.cdc.gov/exposurereport/whats_new_071922_1.html
        
       | edumucelli wrote:
       | We can reach high productivity of fruits and vegetables without
       | fossil fuels: https://climateheroes.org/perrine-and-charles-
       | herve-gruyer-p...
        
       | zackmorris wrote:
       | I think of the GMO/pesticide/herbicide approach like smoking. You
       | may use it for years without issue, but then wake up one day and
       | find yourself unable to eat whole wheat like I did.
       | 
       | The gluten-free movement, the autoimmune diseases we're seeing,
       | the continuing rise of neurological disorders like ADHD and
       | autism.. they're caused by factory farming. The literature may
       | not have reached consensus on that yet, but the trends are
       | obvious and unmistakable now.
       | 
       | My peer group called this out back in the 90s before it went big,
       | but nobody ever listens to us because 1) I was a teenager and 2)
       | the people I listen to and admire are all poor academics. There
       | was profit to be made!
       | 
       | It took 3 years, but I was finally able to get my digestive
       | troubles into remission. I believe what happened is that my
       | enteric nervous system got disrupted with neuropathy when I went
       | through profound burnout in 2019. So the valves in my digestive
       | system were opening and closing at the wrong times and I
       | developed all kinds of food sensitivities. The cure is to take a
       | B complex every day, specifically B1 (thiamine) and saturated fat
       | to heal the nerves, so bacon and eggs is one of the best things
       | I've found. I take a "stress" B complex that's less concentrated
       | so I can have it every day. I've regained the ability to eat
       | nightshades, but wheat/legumes/milk/nuts are still a problem.
       | 
       | Does anyone know of any startups working to isolate and remove
       | the GMO contamination from crops? There would be considerable
       | money in bringing back pre-GMO crop varieties, since such a large
       | percentage of the population can't eat what's on store shelves
       | now. If we do, our digestion shuts down, we get severe
       | inflammation, we get metabolic syndrome, we get diabetes, our
       | quality of life diminishes to effectively nothing.. you see what
       | I'm saying. They could call the crops heirloom or organic and
       | charge twice as much and I and millions of other people would
       | gladly buy them.
       | 
       | Edit: since science is letting the population down at a level
       | approaching conspiracy, I've embraced magical thinking in my own
       | life. I find that holistic models simply perform better. I
       | learned about the neuropathy issue here (no affiliation):
       | 
       | https://www.youtube.com/c/WholeBodyHealingwithJen
        
         | adamgordonbell wrote:
         | What makes GMOs problematic?
        
           | soperj wrote:
           | They're mostly modified so that they can handle herbicides.
        
             | adamgordonbell wrote:
             | I'm not sure why something handling herbicides makes it
             | problematic for eating? Is it because it will then have
             | more herbicides on it or because you feel the incentives
             | behind GMO are off or is their some more immediate problem?
        
               | soperj wrote:
               | It's more than just food for eating. For instance, in BC
               | they plant GMO round up ready pine, and then spray clear
               | cuts and forest fire areas with round up, so that they
               | can plant mono-culture pine stands. This has caused
               | massive forest fire issues which also results flooding
               | issues, along with biodiversity issues.
        
             | mattwest wrote:
             | But that's only because the originators of the first GMO
             | seeds had to be firms with plenty of capital and R&D
             | capacity ie. chemical companies. They also had the double
             | revenue stream of seeds + herbicide. Herbicide resistance
             | is also the most attractive seed trait in terms of farmer
             | adoption.
             | 
             | Now, the cost of generating GMO seeds is much lower. We
             | have more firms creating GMO with traits beyond herbicide
             | resistance. These genotypes will have value for processors,
             | retailers, and consumers. Be careful to not tarnish the
             | reputation of GMO seeds before we realize their true
             | potential.
        
       | hirundo wrote:
       | We're having a wet year and the weed growth is impressive. I've
       | considered spraying Roundup to help control them but I'm
       | concerned about the affect on my pets. Then I talked to my
       | neighbor who regularly uses Roundup. He said that he sprayed a
       | few weeks ago, and his weeds "just kinda look a little tired"
       | instead of gone. If that's all the result I'd get why take the
       | risk.
       | 
       | But I've spent around 10 hours walking behind a weed whacker in
       | the last month. That's not my favorite chore and I'm willing to
       | take some risks to trim it down a bit.
        
         | upofadown wrote:
         | Don't put glyphosate on your lawn unless you don't want to have
         | a lawn anymore.
        
         | stinos wrote:
         | What did you do after weed whacker usage? If you didn't remove
         | all cuttings, there's your main problem. (also: 10 hours? how
         | large is that piece of land?)
        
           | hirundo wrote:
           | I removed the cuttings in past years, but it doesn't seem to
           | have an effect. I think every inch of soil is throroughly
           | saturated with a large variety of seeds. After whacking it
           | down it's just a smooth carpet of green. So I gave up on the
           | removal as not worth the effort.
        
             | peteradio wrote:
             | Is this a garden of a yard you are maintaining? Cultivating
             | a garden before you see weeds cuts down on the weed seed
             | bank. One of those things that takes rigorous practice for
             | a year or more before it is obviously having a long term
             | positive impact.
        
               | hirundo wrote:
               | It's the opposite of a garden, it's a rural lot next to
               | several million acres of wilderness forest. Everything
               | growing here is a volunteer, there is no lawn, I've
               | planted nothing.
               | 
               | And there's plenty of wind constantly bringing more
               | volunteers. This time of year I can almost see them
               | growing.
               | 
               | Should that change my weeding strategy?
        
               | peteradio wrote:
               | I'm a one trick pony, if it isn't a garden I don't know.
               | Perhaps see if you can find out what national parks do
               | for their parking lots?
        
             | stinos wrote:
             | If you leave the cuttings they'll decompose and fertilize
             | the soil, giving advantage to fast growing weeds. Possibly
             | also add nitrogen deposition from surrounding
             | industry/agriculture to that, and you have an ideal cycle
             | for lots of biomass. Mowing like twice a year and removing
             | cuttings on the other hand can and usually does break that
             | cycle, can take some years, resulting in less fierce
             | growth, and more slow-growing species.
        
         | goda90 wrote:
         | I recommend reassessing what you consider a weed as well. I
         | only pull up stuff with thorns that don't produce edible fruit
         | and anything that might compete with that I've intentionally
         | planted. That means the rest of my yard has dandelions,
         | violets, clover, creeping Charlie, other random wildflowers
         | throughout the grass. Mowing occasionally deals with the baby
         | trees.
        
           | hirundo wrote:
           | Anything growing up through the gravel is a weed. Anything
           | growing more than a few inches tall under a tree near the
           | house, with the potential to be a fire ladder, is a weed.
           | 
           | I think that most of the "weeds" are beautiful, I have
           | pictures of many of their flowers on my walls. But I can't
           | afford that beauty near the house in wildfire country. And
           | I'd like to keep my gravelled areas clear, including the
           | driveway and around the structures, and asphalt or concrete
           | aren't options.
        
         | mattwest wrote:
         | Glyphosate can take up to 3 weeks to take full effect. There
         | are a handful of resistant weeds. Palmer amaranth (pigweed) is
         | one. Otherwise it is very effective.
         | 
         | If you don't want to use glyphosate that's totally fine, but
         | just know that residential use is essentially a non-factor in
         | these studies.
        
         | docandrew wrote:
         | I've had great luck with a mixture of high-concentrate vinegar,
         | a little dish soap, and some salt. It absolutely puts Roundup
         | to shame. This mix is non-selective though so be careful around
         | the plants/grass you want to keep.
         | 
         | Using this mix with a battery-powered backpack sprayer is
         | AWESOME.
         | 
         | Edit: Make sure you rinse the sprayer real well afterwards
         | though, vinegar and salt aren't great for the seals/pump.
        
         | cj wrote:
         | Didn't Roundup reformulate their product?
         | 
         | I'm under the impression that the roundup from 15 years ago is
         | completely different than what's in stores today.
        
           | mattwest wrote:
           | It just depends on what you buy. Read the label, as it's what
           | the law requires anyway.
           | 
           | Roundups active ingredient is glyphosate and they have added
           | or removed other supplementary ingredients over the years for
           | different reasons. Some are emulsifiers. Others are
           | additional herbicides which may cause quicker "browning" to
           | please the customer
        
       | dmos62 wrote:
       | Side question: any sign of at least borderline-viable farming
       | techniques without pesticides or herbicides? By viable I mean, as
       | a complete replacement for current agriculture.
       | 
       | I know next to nothing about this, but have had some shower
       | thoughts that a different agriculture system could be viable if
       | we increased our expectations for farming's labour intensity. I
       | probably got the idea from permaculture videos, because they seem
       | to get impressive results, but it also requires some skill and a
       | lot of work.
       | 
       | I'm half-expecting a hail of downvotes, but maybe I'll find other
       | people that have been wondering the same.
        
         | lbriner wrote:
         | I think this is the $10B question!
         | 
         | It would seem that altermatives which are much more friendly to
         | the planet involve lower yields but of arguably higher quality.
         | 
         | This would mean food would be more expensive, although most
         | western nations eat too much anyway and should appreciate that
         | something as simple as food isn't cheap by definition,
         | especially when we are effectively paying someone else to do
         | all the work.
         | 
         | The other big question is about eating meat (or at least as
         | much meat as we do) since if we could reduce wasted land for
         | animals, we would have more space to grow crops which could
         | make up the shortfall of the lower yields.
        
           | reedjosh wrote:
           | There is soooo much land that cows graze on that can't really
           | produce crops.
           | 
           | Space isn't an issue caused by meat consumption. Further cows
           | often eat the parts of crops we won't like corn stalks.
           | 
           | Cows and other ruminants are kind of miracles and absolutely
           | need to be part of our food supply.
        
           | throwaway0a5e wrote:
           | Literally all of societal progress is built on the back of
           | "that thing we used to spend a bunch of time/money on, well
           | we made it cheap and can now redirect that productivity and
           | resources elsewhere" for every conceivable value of "thing",
           | food, clothes, written communication, transportation, energy,
           | consumer junk.
           | 
           | What you are arguing for is a non-starter. Society will not
           | accept higher costs for any duration of time. Some route
           | around the problem that is driving up prices will be found.
        
           | [deleted]
        
         | dzink wrote:
         | Farming is a competition between pests, weather, consumer
         | demands for perfect looking fruit, prices undercut by places
         | with less regulation (or more subsidies), and your actual skill
         | in caring for the farm. It's a real gamble every year for
         | farmers. This at baseline would raise the costs of food as
         | you'd get less crops per acre or end up seeing retailers go for
         | vendors abroad who still use the chemical and made a larger
         | crop.
        
         | carapace wrote:
         | More than borderline, there are many many examples these days
         | of people practicing forms of ecologically-informed agriculture
         | that match or exceed the yields of destructive systems and
         | methods.
         | 
         | When I first heard about Permaculture in the late 80's it was
         | still pretty obscure, and regenerative agriculture in general
         | was "hippie-dippy". Nowadays there are thousand of projects
         | with videos on the youtube, and people are practicing
         | ecologically harmonious farming all over the world. See
         | especially Gabe Brown's talk linked below, he's not replacing
         | current agriculture, just updating it with scientifically-
         | grounded techniques that improve the volume and vitality of his
         | topsoil while being more profitable.
         | 
         | Quoting from some notes I've been keeping:
         | 
         | There's the "Grow Biointensive" method which is designed to
         | provide a complete diet in a small space while also building
         | soil and fertility. They have been dialing it in for forty
         | years and now have a turn-key system that is implemented and
         | functioning all over the world.
         | 
         | => http://growbiointensive.org/ Grow Biointensive
         | 
         | (These folks are also selling their system, but they also have
         | e.g. manuals you can download for free. I find their site
         | curiously hard to use.)
         | 
         | ## Permaculture
         | 
         | Permaculture could be called "applied ecology" (with a kind of
         | hippie spin.) and a similar school (or parallel evolution)
         | called "Syntropic" Agriculture. Both of these systems aim to
         | mimic natural ecosystems to create "food forests" that produce
         | crops year-round without inputs (no fertilizer, no irrigation.)
         | The process takes 5-15 years or so but then is self-sustaining
         | and regenerative.
         | 
         | For Permaculture I find Toby Hemenway's (RIP) videos very good:
         | 
         | => https://tobyhemenway.com/videos/how-permaculture-can-save-
         | hu...
         | 
         | => https://tobyhemenway.com/videos/redesigning-civilization-
         | wit...
         | 
         | There's a very lively and civil forum at
         | 
         | => https://permies.com/forums
         | 
         | ## Syntropic agriculture
         | 
         | => https://agendagotsch.com/en/what-is-syntropic-farming/
         | Syntropic agriculture
         | 
         | (FWIW, I find Gotsch's writing (in English) to be impenetrable,
         | even though I pretty much know what he's doing. Anyway, his
         | results are incontrovertable.)
         | 
         | I'm afraid I don't have a good link in re: Food Forests and
         | eco-mimetic agriculture yet. This "Plant Abundance" fellow's
         | youtube channel might be a good place to start, in any event
         | it's a great example:
         | 
         | => https://www.youtube.com/channel/UCEFpzAuyFlLzshQR4_dkCsQ
         | "Plant Abundance" (youtube)
         | 
         | ## Growing Power
         | 
         | If you really wanted to maximize food production and aren't
         | afraid of building insfrastucture (like greenhouses and fish
         | tanks) there's the (sadly now defunct) *Growing Power* model:
         | 
         | => https://en.wikipedia.org/wiki/Growing_Power
         | 
         | => https://www.youtube.com/watch?v=vs7BG4lH3m4
         | 
         | => https://www.youtube.com/watch?v=jV9CCxdkOng
         | 
         | They used an integrated greenhouse/aquaculture/compost system
         | to produce massive amounts of food right through Milwaukee
         | winters.
         | 
         | ## Regenerative Agriculture
         | 
         | Then there is the whole field (no pun intended) of
         | *Regenerative agriculture*, e.g.:
         | 
         | => https://www.youtube.com/watch?v=uUmIdq0D6-A "Treating the
         | Farm as an Ecosystem with Gabe Brown Part 1, The 5 Tenets of
         | Soil Health" (youtube)
         | 
         | => https://www.youtube.com/watch?v=zXRNF_1X2fU "Symphony Of The
         | Soil" Official Trailer (youtube)
         | 
         | This is very much non-hippie, very much grounded in (often
         | cutting-edge) science (ecology, microbiology, etc.) and
         | ecologically and _economically_ superior to artificial methods
         | (e.g. Brown makes money. It 's actually weird that more people
         | aren't adopting these methods faster. You make more money, have
         | fewer expenses, and your topsoil builds up year-on-year rather
         | than washing away in erosion.)
         | 
         | ## Miyawaki method
         | 
         | For regenerating native forests, not agriculture _per se_.
         | 
         | => https://en.wikipedia.org/wiki/Akira_Miyawaki
        
           | dmos62 wrote:
           | That's exactly what I was interested in. Thanks for the hand-
           | picked recommendations!
        
             | carapace wrote:
             | Cheers! I'm working up a kind of catalog or directory of
             | "ecological living". It really seems like we have all the
             | solutions, we just need to "get 'er done!"
        
         | verisimi wrote:
         | You can't run the corporate governance system on permaculture!
         | People managing a small plot of land and getting an abundant
         | amount of clean, good food won't fly.
         | 
         | What we need are more massive farms, with just one crop,
         | roundup ready seeds, imported fertiliser, etc - all owned by
         | charitable (tax-free!) billionaire foundations for the
         | betterment of us all! Get with the program!
         | 
         | PS I'm being downvoted - but what's the problem? Bill Gates
         | "owns less than 1 percent of the nation's total farmland" (from
         | https://nypost.com/2022/06/30/bill-gates-purchase-of-
         | north-d...).
        
           | m_coder wrote:
           | I believe you are on target. Small plots of land are on
           | average far more productive per acre than large mono cropping
           | plantations.
           | 
           | "Dacha gardening accounts for about 3% of the arable land
           | used in agriculture, but grows an astounding 50% by value of
           | the food eaten by Russians." (from
           | https://smallfarmersjournal.com/russian-dacha-gardens)
        
             | pas wrote:
             | > Small plots of land are on average far more productive
             | per acre than large mono cropping plantations.
             | 
             | the bottleneck is not exactly land, but cost, manpower,
             | etc. that's why industrial farming dominates the food and
             | feedstock sectors.
        
               | m_coder wrote:
               | You are right on target however I am not seeing people
               | here understanding that the tight spot is not land but
               | manpower.
               | 
               | It seems to me that people think that if the first farm
               | is more efficient in converting labor, dollars and cheap
               | fuel into food than the second farm, then the first is
               | the most efficient farm across all categories including
               | land use. When one of the pieces changes (for instance
               | fuel costs) then the formula needs to be revisited.
               | 
               | Realizing that personal, scientific and careful
               | management of land yields more food per acre without agri
               | chemical products is an important first step to thinking
               | about the picture even if the low cost of fuel is a
               | current reality.
        
             | bluGill wrote:
             | that isn't a fair comparison though. Small farms grow high
             | value crops that need a lot of labor, large farms that grow
             | the same crops are even more productive (not by much
             | though), except that there isn't enough demand to support a
             | large farm growing those crops. There is a large demand for
             | corn, so a lot of large farms grow it.
        
           | hutzlibu wrote:
           | "You can't run the corporate governance system on
           | permaculture! People managing a small plot of land and
           | getting an abundant amount of clean, good food won't fly."
           | 
           | I have seen quite some permaculture farms, but abundance of
           | food I have never wittnessed, compared to conventional
           | (organic) farming. Rather big talks and low yield.
           | 
           | Don't get me wrong, I believe we could feed the world without
           | the need of mass scale poison, but not while blinded by
           | dogma.
        
         | mjhay wrote:
         | If we're willing to accept higher labor intensiveness, there's
         | plenty of very realistic farming techniques that could be
         | reintroduced. For example:
         | 
         | - Off-season cover crops like legumes, etc both can fix
         | nitrogen and out-compete weeds.
         | 
         | - Intercropping, where different crops are planted in proximity
         | (like alternating rows). This is less susceptible to pests and
         | disease than monocultures, and the plants can be chosen to
         | mutually enhance each other's fitness.
         | 
         | In general, a lot of these techniques also give a healthier
         | ecosystem, with more pollinators and predators of pests. The
         | yields can be excellent and sustainable, but it is more labor.
         | However, there's plenty of bullshit jobs[0] out there, and many
         | people in them might find this kind of work more meaningful. I
         | think a future society would do well to allocate labor with
         | these goals in mind.
         | 
         | [0] https://en.wikipedia.org/wiki/Bullshit_Jobs
        
           | Loughla wrote:
           | >If we're willing to accept higher labor intensiveness
           | 
           | In general will translate to
           | 
           | >If we're willing to accept higher costs
           | 
           | We may be willing to accept the first one, but I am
           | absolutely not convinced of the second.
        
             | mjhay wrote:
             | Current industrial agriculture isn't physically sustainable
             | in the long run for many reasons (soil loss, depleted
             | aquifers, salinity), so the status-quo isn't a long-term
             | option. Either we figure out how to feed billions of people
             | sustainably, or things will get rather unpleasant in the
             | future.
             | 
             | I don't disagree with you though.
        
             | mdavis6890 wrote:
             | The problem with the word "costs" is that it's too easy to
             | conflate this with money, and just think it means spending
             | more of an abstract and essentially unlimited resource
             | (money).
             | 
             | The reality is that it means we will HAVE LESS STUFF, food
             | or otherwise, because we are increasing the effort required
             | to generate a unit of food.
        
             | sillystuff wrote:
             | Florida farm workers got McDonald's to agree to paying a
             | penny per pound extra for tomatoes where the penny was to
             | go directly to the farm workers' wages. This resulted in a
             | 71% increase in farm worker pay.
             | 
             | It appears that labor costs are not a significant portion
             | of the price of produce. Of course, this would not apply if
             | automated harvesting had to be replaced by manual labor.
             | 
             | https://www.reuters.com/article/idUSN0933192520070409
        
         | cameldrv wrote:
         | There are several companies that are using machines with
         | computer vision to identify weeds and then either squirt a tiny
         | amount of herbicide (Blue River/John Deere) onto them, or burn
         | them with a laser (Carbon Robotics, others).
        
           | yeldarb wrote:
           | Or flamethrower https://hackaday.com/2021/09/11/dont-sleep-
           | on-the-lawn-there...
        
         | tonyhb wrote:
         | Yes: https://www.gothamgreens.com/.
         | 
         | They grow foods in hydroponic warehouses with no soil and no
         | pesticides. You can find them in Whole Foods.
         | 
         | I'm a huge fan of urban farming like this.
        
           | progre wrote:
           | I wonder what the energy budget look like for an operation
           | like that. The argument against urban farming is that it is
           | energy intesive and not really space efficient if you include
           | the space needed for the extra energy production.
           | 
           | It would be interesting to see a comparison with conventional
           | farming where the energy to produce fertilizer was included.
        
           | diordiderot wrote:
           | Thats cool but you probably need ~2000 calories a day which
           | would require chewing through 28 pounds of lettuce(70
           | kcal/lb) which ain't easy.
        
           | mattwest wrote:
           | They aren't growing significant calories and hydroponics do
           | not currently have the ability to do so in a way that
           | competes with soil cropping
        
       | SquareWheel wrote:
       | So the "animals" mentioned in the title refers to roundworms, a
       | parasite that lives in soil. Not something you exactly want, but
       | also not something you would expect to be targeted by a
       | herbicide.
       | 
       | Glyphosate discussions always brings out people with strong
       | opinions, but the product is studied extensively by researchers
       | and the majority of studies have not shown harm. That doesn't
       | prove it's safe of course, but it's where we're currently at.
       | 
       | Because Roundup is such an important part of our agricultural
       | industry, it should continue to be studied in depth. This study
       | and others like it are important to ensuring that farming at
       | scale remains safe for human consumption, as well as minimizes
       | environmental impact.
        
         | whalesalad wrote:
        
         | dekhn wrote:
         | c elegans are roundworms, but they are not parasites. They eat
         | bacteria and yeast that grow on rotting fruit and other
         | decaying matter.
         | 
         | If roundup or glyphosate had these effects on c. elegans I'd
         | expect a large-scale visibly noticeable impact on crop yields.
        
         | wirrbel wrote:
         | To me it appears that roundup kind of blocks an honest
         | discussion on other causes of declining insect populations.
        
           | soperj wrote:
           | what would these be? edit: this was a genuine inquisitive
           | question, not snarkiness.
        
             | mattwest wrote:
             | One factor could be land use and reduction of the overall
             | richness of our ecosystem. That could be highways, cities,
             | suburbs, timberland, and the coverage of monoculture crops
        
         | user3939382 wrote:
         | > the product is studied extensively by researchers
         | 
         | Which researchers and funded by whom? This is the line Monsanto
         | brings out every time. It turns out their corrupt research
         | couldn't convince a court, who decided glyphosate was to blame
         | for cancer, to the tune of $300M c.f. Johnson v. Monsanto Co.
         | 
         | And it's not just roundworms
         | https://sites.psu.edu/soilmicrobiology/projects/glyphosate-i...
         | 
         | This chemical is bad news and the only reason it's legal is
         | regulatory capture by Monsanto/Bayer.
        
           | ekianjo wrote:
           | you know that this judgment was very controversial or you
           | believe everything is just 1 and zeroes in life?
        
             | saiya-jin wrote:
             | Seriously, WTF is wrong with people... we repeatedly
             | polluted whole world with harmful substances like lead that
             | killed god knows how many people and damaged in some way
             | _everybody_ else with this kind of logic, yet people have
             | the balls to come up with  "innocent until proven guilty by
             | 100 peer reviews" mantra for... MONSANTO
             | 
             | I don't believe, unlike many, that they are comically evil
             | guys. Just playing a god for profit with stuff they
             | probably understand only in lower 90 percentile range,
             | especially second, third etc. order effects. And probably
             | too over-invested in direction company took decades ago, so
             | nobody looking at bonuses as drive will change its
             | direction dramatically.
        
               | DiggyJohnson wrote:
               | Choosing to blindly believe one side over blindly
               | believing the other side is a dubious approach to these
               | things. I care about environmental issues, and have no
               | love for many aspects of Monsanto's business and history,
               | but your emotional appeal is extremely unconvincing.
               | 
               | > for Monsanto
               | 
               | GP isn't making their comment "for Monsanto", but for the
               | sake of seeking the truth on _this specific issue._ You
               | will continue to be shocked until you change your
               | perspective on how we ought to evaluate nuanced issues.
               | Especially when those issues have to do with global food
               | production.
        
               | soperj wrote:
               | > sake of seeking the truth on this specific issue
               | 
               | I don't disagree with you, I also don't think we should
               | be using the product when the truth is as clouded as it
               | is. So ban it until the truth comes out.
        
               | gruez wrote:
               | >So ban it until the truth comes out.
               | 
               | Okay but given that we have endless studies already, it
               | seems like "until the truth comes out" really means
               | "until my _preferred conclusion_ comes out ".
        
               | soperj wrote:
               | My preferred conclusion would be that it's actually safe,
               | since we're using a massive amount of it already and
               | we're all exposed.
        
               | drekk wrote:
               | It took decades to prove conclusively that cigarettes
               | cause cancer in humans. Similarly to tobacco companies
               | Monsanto is subsidizing research that just happens to
               | find no harms with RoundUp. I'm sure it's fine though, no
               | big deal that trace amounts can be found in urine samples
               | from 80% of Americans. https://amp.theguardian.com/us-
               | news/2022/jul/09/weedkiller-g...
        
               | gruez wrote:
               | >It took decades to prove conclusively that cigarettes
               | cause cancer in humans.
               | 
               | Glyphosate has been around for almost 5 decades.
               | Wikipedia says "The consensus among national pesticide
               | regulatory agencies and scientific organizations is that
               | labeled uses of glyphosate have demonstrated no evidence
               | of human carcinogenicity"[1]. If you think this is not
               | "conclusively" enough, how much longer/more evidence do
               | you need? Is this a standard that we should apply to
               | everything[2], or just chemicals made my evil
               | multinational corporations? Maybe we should delay rolling
               | out cell phones for a few decades _just to be sure_ that
               | they don 't cause brain cancer?
               | 
               | [1] https://en.wikipedia.org/wiki/Glyphosate
               | 
               | [2] https://slatestarcodex.com/2014/08/14/beware-
               | isolated-demand...
        
             | faeriechangling wrote:
             | I have to take it at face value to a degree otherwise
             | Monsanto can fire cannons of money at scientists and yell
             | "the science isn't settled!" until the end of humanity even
             | if roundup really did cause cancer.
             | 
             | At the same time I think there is a limit to how bad
             | roundup can be to have fought off criticism in EVERY
             | country and remain on the market.
        
               | stickfigure wrote:
               | Have you ever sat on a jury? Seen how that particular
               | sausage is made?
        
           | gruez wrote:
           | >It turns out their corrupt research couldn't convince a
           | court, who decided glyphosate was to blame for cancer, to the
           | tune of $300M c.f. Johnson v. Monsanto Co.
           | 
           | What makes you think a jury of 6-12 laypeople are better
           | qualified to make conclusions on the available evidence than
           | scientists?
        
             | user3939382 wrote:
             | Because the jury are listening to experts from both sides
             | of the case, and those experts are qualified to draw
             | conclusions. Also "scientists" are not uniformly on the
             | side of Monsanto/Bayer/glyphosate, as your comment seems to
             | suggest.
        
               | pjlegato wrote:
               | If someone is not qualified as an expert on a given topic
               | themselves, they have no rational basis for evaluating
               | competing and mutually incompatible claims generated by
               | two parties who are each qualified experts. The process
               | devolves into mere sophistry.
        
               | gruez wrote:
               | >Because the jury are listening to experts from both
               | sides of the case, and those experts are qualified to
               | draw conclusions.
               | 
               | That doesn't answer the question. What makes you think
               | that a jury of 6-12 laypeople are better able to
               | determine the truth from 2 conflicting teams of experts,
               | than a team of experts versed in the relevant field?
               | 
               | >Also "scientists" are not uniformly on the side of
               | Monsanto/Bayer/glyphosate, as your comment seems to
               | suggest.
               | 
               | They seem to be uniformly on the side of
               | Monsanto/Bayer/glyphosate, according to wikipedia.
               | 
               | >The consensus among national pesticide regulatory
               | agencies and scientific organizations is that labeled
               | uses of glyphosate have demonstrated no evidence of human
               | carcinogenicity. [...]
               | 
               | there's more but I'm not going to quote the whole
               | paragraph
               | 
               | https://en.wikipedia.org/wiki/Glyphosate
        
               | indiv0 wrote:
               | Not going to quote the whole paragraph? The paragraph
               | that goes on to say that there's an increased risk of
               | non-Hodgkin lymphoma and other issues?
               | 
               | > The German Federal Institute for Risk Assessment
               | toxicology review in 2013 found that with regard to
               | positive correlations between exposure to glyphosate
               | formulations and risk of various cancers, including non-
               | Hodgkin lymphoma, "the available data is contradictory
               | and far from being convincing".[11] A meta-analysis
               | published in 2014 identified an increased risk of NHL in
               | workers exposed to glyphosate formulations.[12] In March
               | 2015, the World Health Organization's International
               | Agency for Research on Cancer (IARC) classified
               | glyphosate as "probably carcinogenic in humans" (category
               | 2A) based on epidemiological studies, animal studies, and
               | in vitro studies.[8][13][14][15] In contrast, the
               | European Food Safety Authority concluded in November 2015
               | that "the substance is unlikely to be genotoxic (i.e.
               | damaging to DNA) or to pose a carcinogenic threat to
               | humans", later clarifying that while carcinogenic
               | glyphosate-containing formulations may exist, studies
               | "that look solely at the active substance glyphosate do
               | not show this effect."[16][17] In 2017, the European
               | Chemicals Agency (ECHA) classified glyphosate as causing
               | serious eye damage and as toxic to aquatic life, but did
               | not find evidence implicating it as a carcinogen, a
               | mutagen, toxic to reproduction, nor toxic to specific
               | organs.[18]
               | 
               | Personally I trust a jury of 6-12 laypeople or the
               | *European Chemicals Agency* over a company with a vested
               | interest in keeping their product on the market.
        
               | gruez wrote:
               | > Not going to quote the whole paragraph? The paragraph
               | that goes on to say that there's an increased risk of
               | non-Hodgkin lymphoma and other issues?
               | 
               | I'm glad that you quoted the whole paragraph, but this
               | seems to put a damper on your conclusion
               | 
               | >"the available data is contradictory and far from being
               | convincing"
               | 
               | >Personally I trust a jury of 6-12 laypeople or the
               | _European Chemicals Agency_ over a company with a vested
               | interest in keeping their product on the market.
               | 
               | Their conclusion is:
               | 
               | >the European Chemicals Agency (ECHA) classified
               | glyphosate as causing serious eye damage and as toxic to
               | aquatic life, but did not find evidence implicating it as
               | a carcinogen
        
               | user3939382 wrote:
               | It wasn't "just" a jury in the first place, Monsanto
               | appealed and also lost.
        
           | voakbasda wrote:
           | The courts ignored the science. The law has little to do with
           | truth or justice.
        
             | user3939382 wrote:
             | You have no evidence of that. More likely the plaintiff had
             | their own scientific experts who were more persuasive,
             | that's how all technical matters are adjudicated in courts.
        
               | NovemberWhiskey wrote:
               | Nonetheless, surely the point is well-made that just
               | because 12 jurors or 1 judge decide that a presentation
               | is more persuasive does not say anything about the truth
               | value of the underlying science.
               | 
               | Just look at the junk science of the FBI crime labs - and
               | that stuff is being measured at the higher "beyond a
               | reasonable doubt" standard.
        
               | user3939382 wrote:
               | Another factor that makes Monsanto/Bayer look really bad
               | here is that they lost despite having basically an
               | unlimited legal budget with a huge team of lawyers versus
               | this school groundskeeper and their case was so bad they
               | still lost.
        
               | gruez wrote:
               | >having basically an unlimited legal budget with a huge
               | team of lawyers
               | 
               | no, their budget is capped at the amount that they're
               | suing for. If you're getting sued for $1M there's no
               | point in spending more than $1M on lawyers.
               | 
               | >versus this school groundskeeper and their case was so
               | bad they still lost.
               | 
               | According to the court filings for the appeal, Johnson
               | was represented by
               | 
               | >The Miller Firm, LLC Michael J. Miller, Curtis G. Hoke,
               | Jeffrey A. Travers;
               | 
               | >Baum, Hedlund, Aristei & Goldman, P.C.; R. Brent Wisner,
               | Pedram Esfandiary;
               | 
               | >Audet Partners LLP, Mark E. Burton
               | 
               | Something tells me that he wasn't paying for all of this
               | out of pocket.
        
             | NovemberWhiskey wrote:
             | c.f. also the talcum powder lawsuits against J&J.
        
               | scotty79 wrote:
               | Majority of research claimed that J&J talkum powder is
               | safe?
        
               | NovemberWhiskey wrote:
               | Basically, the best studies show no link e.g.
               | https://jamanetwork.com/journals/jama/article-
               | abstract/27584...
               | 
               | The American Cancer Association doesn't list talc at all
               | when talking about risk factors for ovarian cancer:
               | https://www.cancer.org/cancer/ovarian-cancer/about/new-
               | resea...
               | 
               | J&J is winning most of the cases in court, or having
               | large verdicts overturned on appeal, but there are
               | supposedly something like 38,000 cases out there and each
               | one has an outside chance to end up being like the one
               | they lost in Wisconsin state court which initially
               | awarded over $4.69bn to 22 plaintiffs (reduced to $2.11bn
               | on appeal).
        
               | scotty79 wrote:
               | Do you think it really is a risk factor for ovarian
               | cancer?
        
         | kingkawn wrote:
         | These neurotoxins do not deserve the benefit of the doubt until
         | shown otherwise
        
           | gruez wrote:
           | It's a neurotoxin... according to whom? A search for "neuro"
           | in https://en.wikipedia.org/wiki/Glyphosate turns up 0
           | matches. However, the same wikipedia article does mention the
           | mechanism of action
           | 
           | >It inhibits a plant enzyme involved in the synthesis of
           | three aromatic amino acids: tyrosine, tryptophan, and
           | phenylalanine
           | 
           | which seems decidedly not a neurotoxin.
        
         | photochemsyn wrote:
         | This whole subject does reveal the duplicity and manipulation
         | of Bayer-Monsanto on this topic, because they use studies on
         | _purified glyphosate_ to make their claims of harmlessness.
         | 
         | However, RoundUp is glyphosate + surfactants (oily lipid-type
         | molecules) which are needed to dissolve the waxy leaf surface
         | so that the glyphosate can be absorbed by the plant, without
         | which the herbicide would be ineffective.
         | 
         | Studies with RoundUp formulation show the disruption of cell
         | cycle effects, which can lead to cancer in applicators who get
         | exposed. This is a common issue with a wide variety of strong
         | surfactants, for example see this from the Deepwater Horizon
         | blowout, where they dumped tons of a surfactant mix called
         | Corexit:
         | 
         | https://www.sourcewatch.org/index.php?title=Corexit
        
           | shawnz wrote:
           | Surfactants are essentially soaps, right? So surely their
           | safety profile is well understood already and glyphosate is
           | the more important component to be researching anyway?
        
             | ncmncm wrote:
             | "Surely" is the opposite of science. There are as many
             | kinds of surfactants as of acids and bases.
             | 
             | You would not say of an acid, "surely it is essentially
             | vinegar", or of a base "surely it is essentially baking
             | soda".
        
               | shawnz wrote:
               | Are they using an especially unusual choice of surfactant
               | in roundup? Wouldn't it be trivial to just go to one with
               | a better safety profile if it's not the active
               | ingredient? It just doesn't seem like a plausible
               | conspiracy to me that Monsanto would be going to such
               | efforts to hide the side effects of the surfactant they
               | are using. I'm not saying it shouldn't be studied, I'm
               | just saying this doesn't seem like such a huge "gotcha"
               | to me.
        
               | photochemsyn wrote:
               | Plants have waxy leaves; surfactants which dissolve waxes
               | allow the glyphosate to enter the plant; such surfactants
               | tend to be highly potent (i.e, they'd effectively strip
               | oils from skins cells and get into those cells). Soap
               | probably wouldn't dissolve waxes.
               | 
               | Fundamentally, the exact identity of the 'inert
               | ingredients' in Roundup and similar products should be
               | exposed on the label. Currently that's proprietary
               | information, but there's a wide range of toxicity of such
               | substances.
               | 
               | https://pubmed.ncbi.nlm.nih.gov/30951798/
               | 
               | > "(2019) As glyphosate-based-herbicide composition is
               | legally classified as confidential commercial
               | information, confusion concerning the identity and
               | concentrations of co-formulants is common and
               | descriptions of test substances in published studies are
               | often erroneous or incomplete. In order to resolve this
               | confusion, laws requiring disclosure of the chemical
               | composition of pesticide products could be enacted.
               | Research to understand health implications from ingesting
               | these substances is required."
        
           | gabereiser wrote:
           | There will always be people who believe the Bayer-Monsanto
           | propaganda. Just like there are people who believe that
           | burning 100m-year-old plant matter is fine. Just like people
           | believe that there are aliens living among us.
           | 
           | There have been countless studies on the matter. Even without
           | the surfactants it's still a nasty substance.
           | 
           | https://www.frontiersin.org/articles/10.3389/fenvs.2021.7639.
           | ..
           | 
           | https://www.cornucopia.org/2014/03/gut-wrenching-new-
           | studies...
           | 
           | https://www.figo.org/removal-glyphosate-global-usage
           | 
           | https://jech.bmj.com/content/71/6/613
           | 
           | https://ehjournal.biomedcentral.com/articles/10.1186/s12940-.
           | ..
        
         | Dig1t wrote:
         | >Glyphosate discussions always brings out people with strong
         | opinions
         | 
         | That's funny, I've experienced this first hand. There's a guy
         | who comes into the vet clinic I frequent who's dog died of
         | cancer and he drives around with giant decals pasted all over
         | his white van saying that Roundup killed his dog and to stay
         | away from it. He claims that the gardener sprayed his dog
         | deliberately and that his dog died as a result. He is very
         | passionate about it and spends a lot of time evangelizing this
         | cause.
        
         | jiggywiggy wrote:
         | Pesticides & herbecides in general are just not safe at the
         | moment and it's been clear they having been causing lots of
         | health problems.
         | 
         | A lot of people, especially the farmers themselves & people
         | living close to the farms get way too high amounts of
         | pesticides in their system. And I also don't trust the safe
         | amounts allowed are actually properly tested over a lifetime.
         | 
         | Causing all kinds of issues, among parkinsons and such, take
         | France for instance:
         | https://beyondpesticides.org/dailynewsblog/2021/06/vineyard-...
        
           | gcheong wrote:
           | This site seems to promote organic agricultural practices as
           | pesticide-safe but organic farming uses some of the most
           | dangerous pesticides (e.g copper sulfate) precisely because
           | of the anti-scientific requirement that anything used must be
           | of "natural" origin, which is just the naturalistic fallacy.
           | The bias here is clear.
        
         | throwaway4aday wrote:
         | I wonder how much the effect on microorganisms has been
         | studied. I have a small hunch that a lot of the weird reactions
         | people have to various plants can be traced back to glyphosate
         | and its effect on our gut biome.
        
         | slimsag wrote:
         | Do you know if there /are/ any studies done with smaller
         | mammals, out of curiosity? My worry is always that we're
         | poisoning our dogs/cats, where a toxic amount I imagine is much
         | smaller
        
           | TedDoesntTalk wrote:
           | You're worried about dogs and not children or adults?
        
           | nemo44x wrote:
           | You want to wait for it to dry before letting animals and
           | people in the area you have applied Roundup.
        
             | slimsag wrote:
             | Of course, but it's still there after drying. dogs/cats
             | sniff the ground, lay on it, eat bugs that have interacted
             | with it, etc. (hopefully not for all of these, but I am
             | sure they do)
        
               | cma wrote:
               | Some things completely change character after drying.
               | Permethrin will kill cats while wet (like just after
               | applying topically to a dog), but they wont absorb enough
               | of it dry. And it doesn't really re-wet by just adding
               | water (permethrin for hiking stays on clothes through 30
               | washes or something).
               | 
               | I'm not sure if it chemically changes or if it starts out
               | in some kind of emulsion or something that can't be
               | recreated by just rewetting with water.
        
               | slimsag wrote:
               | That's really interesting, I didn't know that. Makes me
               | wonder how many herbicides / insecticides are like this
               | for sure
        
         | dzink wrote:
         | That roundworm aerates the soil and is critical for the health
         | of plants you're eating as well. It's also a proxy for nervous
         | system reactions.
        
           | Symmetry wrote:
           | On the other hand, in the Americas it's an invasive species
           | and many crops were doing fine before it's introduction so
           | I'm not sure I'd call it critical for plants health. In the
           | end we can compare yield in fields with roundup applied and
           | those without and compare yields to find out the overall
           | effect on plants.
           | 
           | But the dangers of it affecting other animals' nervous
           | systems the same way it affects roundworms is a serious
           | worry.
        
             | pvaldes wrote:
             | Footnote: Roundworms and Earthworms are different animals.
             | 
             | The animals cited in this study are roundworms and belong
             | to the Filum Nematoda, one of the most frequent animals in
             | this planet and also one of the most overlooked.
             | 
             | Most of them are not parasite animals, but we know more
             | about the parasites because they cause gross diseases in
             | humans.
             | 
             | Earthworms are the common pink worms found on soil, they
             | belong to Filum Annelida (and is true that some european
             | earthworms invaded America a few thousands years ago).
             | 
             | Earthworms and humans are basically not directly linked in
             | the trophic chain. We don't feed on them, and they don't
             | feed on us directly or cause us diseases.
        
             | dekhn wrote:
             | The roundworm in this study, C. Elegans is not invasive.
             | It's one of the critical components of an ecosystem. You
             | are thinking of other roundworms.
        
               | Symmetry wrote:
               | Hmm, I was assuming the OP was extending the _c elegans_
               | result to earthworms since I 've never heard of _c
               | elegans_ aerating soil. And now that I go google it I 'm
               | seeing lots of stuff on _c elegans_ requiring aerated
               | soil but none on it doing it itself so I think I 'm
               | correct in my assumption?
        
               | dekhn wrote:
               | c. elegans help maintain the decomposition pipeline, not
               | soil aeration.
               | 
               | There are a few things that if they were lost globally
               | would greatly affect the necessary process of
               | decomposition.
               | 
               | A lot of what's written about c. elegans environment has
               | been overturned. It was thought to be a soil nematode,
               | but it's really most common in rotting fruit.
        
           | XorNot wrote:
           | Glyphosate doesn't _last_ in soil though, it 's broken down
           | in a few days by soil bacteria.
        
             | katbyte wrote:
             | Doesn't mean that it doesn't last elsewhere, studies in BC
             | have shown that is persists in plants that are sprayed but
             | don't die for at least a year
             | https://vancouversun.com/news/local-news/the-herbicide-
             | glyph...
             | 
             | Which makes the practice above of spraying replanted
             | forests so "the good trees grow faster" even more abhorrent
        
               | soperj wrote:
               | > the good trees grow faster
               | 
               | They replant with round-up ready pine, so they spray to
               | kill aspen which is a firebreak species, and grow massive
               | pine stands which are the opposite. It's the major reason
               | for the massive forest fires we've had lately (and thus
               | the massive flooding).
        
             | gruez wrote:
             | "a few days" is the lower end. From wikipedia:
             | 
             | >The half-life of glyphosate in soil ranges between 2 and
             | 197 days; a typical field half-life of 47 days has been
             | suggested. Soil and climate conditions affect glyphosate's
             | persistence in soil. The median half-life of glyphosate in
             | water varies from a few to 91 days.[57] At a site in Texas,
             | half-life was as little as three days. A site in Iowa had a
             | half-life of 141.9 days
        
             | alfor wrote:
             | If it show up in your urine, it mean it lasted too long.
             | 
             | It is also a powerful chelating agent (make you lose
             | minerals) is another concern for humans.
             | 
             | "Although the chelating properties are well known, this
             | potential additional environmental risk was never
             | adequately considered in the regulatory risk assessment
             | (EFSA 2015a, 2015b)."
             | 
             | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823954/#:~:te
             | x....
        
             | giantg2 wrote:
             | Do you have a source for that? I thought the half-life in
             | soil was 90 days. Certainly would be perplexing as to how
             | various Roundup products work for months to a year.
        
               | aidenn0 wrote:
               | The long-lasting Roundup products contain other active
               | ingredients in addition to glyphosate.
        
               | giantg2 wrote:
               | It seems regular Roundup has multiple active ingredients
               | these days.
        
             | primroot wrote:
             | Let's not forget adjuvants.
        
             | thecolorblue wrote:
             | I have heard this too, but then how is it showing up in
             | people later on?
        
               | katbyte wrote:
               | It gets into plants and animals during those days
               | https://vancouversun.com/news/local-news/the-herbicide-
               | glyph...
        
         | pvaldes wrote:
         | Soil roundworms are not necessarily parasites. Free living ones
         | have huge populations in the soils and sea bottoms. In ecology
         | handbooks there is often shown a study that found more
         | kilograms of roundworms than kilograms of deer living in the
         | same places.
         | 
         | They are highly influential in fertile soils.
        
       | londons_explore wrote:
       | We keep asking ourself "is this chemical safe".
       | 
       | But what we should be asking is "does use of this chemical have
       | benefits to humans that outweigh the disadvantages to humans".
       | 
       | A weedkiller that harms people might still be a good thing if it
       | has overwhelming benefits too, like for example it saves far more
       | peoples lives through greater food production.
       | 
       | Regulators never seem to see this bigger picture - instead we
       | allowed things that have small benefits and large known harm (eg.
       | leaded fuels), and disallow things that could have huge benefits
       | and tiny harm (gm crops).
       | 
       | Regulators need to be the ones seeing the bigger picture, because
       | the people getting the benefits (eg. farmers) are rarely the ones
       | taking the downsides (eg. cancer risk of those eating the
       | produced food).
        
         | TheMiddleMan wrote:
         | You say this like there aren't alternatives. We can find a way
         | to grow crops that isn't harmful to people.
        
           | stickfigure wrote:
           | > We can find a way
           | 
           | Are you a commercial farmer? What crops, what volume?
        
           | echelon wrote:
           | > We
           | 
           | Who is "we", and why are you including yourself in this?
           | 
           | It's one thing to state that. It's quite another to go and do
           | it.
           | 
           | The farm industry has made a choice. What are you going to do
           | to make them change that? Offer to pay more? Get lawmakers to
           | side with you? Purchase different things at the grocery
           | store?
           | 
           | I think we'll still be talking about glyphosate in another
           | twenty years and that not much will have changed.
        
           | londons_explore wrote:
           | Everything involves some harm to people. For example, if you
           | use a tractor to plough that land, you'll be emitting some
           | diesel particulates giving the people in the area worse
           | health.
           | 
           | If you ban machines and plant everything by hand, someone's
           | going to get a bad back.
           | 
           | Every option involves some harm. The trick is to minimize it.
        
             | kingkawn wrote:
             | Not permanently damaging the soil and causing long term
             | chemical poisoning to the population and our offspring is a
             | pretty basic don't
        
               | bluGill wrote:
               | That plow will do a lot more damage to the soil than
               | roundup.
        
       | lizardactivist wrote:
       | I don't think we will ever understand the amount of death,
       | literally, that Monsanto's products have caused. And what's worse
       | is they were fully aware all along, and still the US government
       | had their back.
        
         | TheBigSalad wrote:
         | What do you mean? People are living longer and our food is
         | safer than ever before. How could you argue otherwise?
        
         | nemo44x wrote:
         | Their products have probably caused more deaths indirectly that
         | from the chemicals themselves. Their chemicals are a major
         | reason starvation isn't a problem (thus saving many lives) and
         | have helped in growing crops so much that we use their
         | byproducts in many things (line HFCS, etc) which has made
         | processed food so incredibly cheap and accessible that we have
         | a diabetes and obesity epidemic.
        
         | docandrew wrote:
         | This is a bit hyperbolic - unless you mean excess deaths caused
         | by obesity, heart disease and diabetes because of how abundant
         | food has gotten.
         | 
         | But starvation is less of a problem anymore, largely because of
         | agricultural advances like fertilizers, machinery enabling
         | better practices (like no-till farming) and yes, herbicides and
         | pesticides.
         | 
         | Undoubtedly there are harmful side effects but they need to be
         | viewed with a sensible cost-benefit analysis.
        
       | assbuttbuttass wrote:
       | But it's perfectly safe to drink, right?
       | https://youtu.be/ovKw6YjqSfM
        
         | vel0city wrote:
         | Its a pretty common practice to include manure when fertilizing
         | a field. Would you eat manure?
         | 
         | There's lots of things that are safe to use in their expected
         | capacities that I probably wouldn't eat.
        
           | a2tech wrote:
           | This comment made me chuckle and I think is an excellent
           | illustration.
           | 
           | There's a lot of people in these threads that don't
           | understand how farming works and the sheer scale of the
           | problem with growing plant matter for food and industry.
           | There are people seriously encouraging manual farming as a
           | solution to the worlds food/pest issues. It boggles my mind--
           | have these people have hand worked a field? Even maintaining
           | an acre of garden as a single person would illustrate the
           | amount of effort you have to put in and the low amount of
           | yield you get in return. I'd love to know how people would
           | get 'selected' as field workers. Because I doubt you'd have
           | people rushing out to till fields by hand unless they're
           | pressed into service.
           | 
           | Personally I'd rather deal with a little extra chemical
           | buildup than reinventing a modern slave class.
        
           | [deleted]
        
         | SquareWheel wrote:
         | Nobody would drink a glass of offered liquid from somebody who
         | is clearly acting antagonistically towards them. Beyond that,
         | there's clearly a difference between something being appealing
         | and safe to drink. The way anti-GMO people tout this as a slam
         | dunk is just intellectual laziness.
        
           | mandmandam wrote:
           | > "anti-GMO people"
           | 
           | There it is. The implication that anyone who isn't
           | unquestionably pro GMOs, is against them, no matter the
           | modification or the company pushing it.
           | 
           | I mean, what kind of an anti-science rube uses
           | "intellectually lazy" arguments, such as "asking a guy who
           | said Roundup is safe to drink to actually drink some".
           | 
           | This, from the guy who conflates RoundUp with it's active
           | ingredient glyphosate. Scientific evidence showing RoundUp is
           | significantly more toxic -
           | https://www.nature.com/articles/s41598-022-17537-w- Hmm, that
           | study was easy to find ...
           | 
           | This, on an article which explicitly calls out how little we
           | know of glyphosate's effect on the nervous system.
           | 
           | This, on an article which notes the terrifying fact that 80%
           | of US urine samples, children included, contain glyphosate.
           | 
           | RoundUp is nasty shit. And I'm not anti-science for being
           | worried about glyphosate in my piss.
        
       | frazbin wrote:
       | In the thread: bunch of tech workers acting like 19th century
       | small farmers. The story here is that chemistry is a blunt tool
       | and in 50 years we won't need it for agriculture. Biocontrols
       | will have totally taken over. In the meantime anything we can do
       | to remove incumbent chemical technologies and create economic
       | room for their replacements is.. important. Why? cause we're
       | gonna need those biocontrols anyway to keep farming at current
       | yields under an evolving pest/weed regime.
       | 
       | We got through the 20th century without sustainable farming. I'm
       | OK with that, it led to things like me existing. Now it's time to
       | focus a little more effort on doing the job properly.
        
         | mattwest wrote:
         | Biocontrols have potential, but they have certainly not taken
         | over. We will always use a combination of herbicides, genetic
         | engineering, RNAi, and biocontrols. The key will be finding a
         | balance between these technologies.
        
       | sokoloff wrote:
       | The animal in question is C. elegans, a soil-dwelling roundworm.
       | So, undeniably an animal, but probably not among the first 50
       | animals that the headline is likely to conjure in the reader's'
       | imagination.
        
       | incomingpain wrote:
       | I feel like Glysophate is equivalent to leaded gasoline. Everyone
       | knows it's bad for everyone but we keep using it. With some near
       | future where we ban it.
        
         | bluGill wrote:
         | There is a difference. With leaded gasoline it was the chemists
         | who study this stuff that knew it was bad trying to convince
         | everyone else. With roundup it is the non-chemists "bloggers"
         | and conspiracy theorists who know it is bad trying to convince
         | everyone else.
        
       | Kim_Bruning wrote:
       | Just to be sure, biologists use a number of model organisms which
       | are well understood. C. Elegans is a model organism for studying
       | genetics and neurophysiology.
       | 
       | https://en.wikipedia.org/wiki/Caenorhabditis_elegans
        
       | chmaynard wrote:
       | If the Environmental Protection Agency (EPA) had the authority to
       | regulate industrial chemicals along the lines of the FDA's
       | regulation of pharmaceuticals, this type of clinical study would
       | have been required before Roundup ever hit the shelves.
        
         | h2odragon wrote:
         | When Roundup first hit shelves, "soil erosion" was the big
         | concern and it was a miracle chemical that enabled "no till"
         | agriculture. Now erosion is not a concern anymore, hardly
         | anyone does more than disc their fields once a decade.
         | 
         | Of course while that _helps_ erosion, it doesn 't fully solve
         | the problem, and it also took down the flood control benefits
         | the erosion mitigation efforts gave us, too.
        
           | meragrin_ wrote:
           | > hardly anyone does more than disc their fields once a
           | decade.
           | 
           | I guess nearly every single of the "hardly anyone" are near
           | me. Pretty much every field seems to be tilled every year or
           | every other year.
        
           | stinos wrote:
           | _Now erosion is not a concern anymore, hardly anyone does
           | more than disc their fields once a decade._
           | 
           | That's a bit of a stretch. Really depends on location and
           | crop type. At least around this local village, lots of hills,
           | it is still an issue. As in: every rainfall which is like a
           | tad rougher than average results in several streets being
           | flooded with mud. Totalling several metric tonnes (official
           | measurements, weird these numbers are weight, not volume) of
           | soil disappearing from only a couple of km^2 of farmland
           | every single year. This isn't the type of issue Roundup or
           | anything like that is going to solve, it really need thorough
           | systematic change.
        
             | h2odragon wrote:
             | > Really depends on location and crop type.
             | 
             | Great point; around me they let the small fields on the
             | hills go back to forest and stopped building little dams.
             | Can still find traces of the horse drawn plowed fields,
             | further up the hills, where they turned furrows to be
             | terraces. Those last got plowed 100+ yr ago in some cases
             | and now stand out from the gullies below them.
        
             | ouid wrote:
             | not weird at all the the measurements are in mass. Mass is
             | conserved, volume is not. For instance what do you get when
             | you add half a yard of silt to a yard of pebbles? thats
             | right, a yard of silty pebbles
        
               | stinos wrote:
               | Makes sense, but only if interpreted as 'mass of dried
               | material (i.e. soil only, not the water in it)' then I
               | guess?
        
         | jlmorton wrote:
         | This is not exactly the first study on glyphosate. There are
         | 857 studies on links on the links between glyphosate and Non-
         | Hodgkin's Lymphoma alone. Pubmed finds 4,585 studies mentioning
         | glyphosate, going back to 1975.
         | 
         | It's an extremely intensively-studied chemical.
        
         | chiefalchemist wrote:
         | Rephrased a bit for those not familiar with the process:
         | 
         | New chemicals can be introduced and are considered innocent
         | until proven guilty.
         | 
         | This was the entry point for forever-chemicals.
         | 
         | https://en.wikipedia.org/wiki/Persistent_organic_pollutant
        
       | giantg2 wrote:
       | File this under "study confirming shit that beekeepers already
       | know". Seeing bees twitching and shaking as they die is pretty
       | common after various herbicide, pesticide, and fungicide
       | applications.
        
         | mattwest wrote:
         | The only reasonable study linking glyphosate to bee harm was
         | designed to mimic large-scale farming application. They used
         | huge concentrations and only found disorientation of bees, but
         | not a reduction in bee population.
         | 
         | Glyphosate is not a neonicotinoid, which is class of chemicals
         | you are probably referring to.
        
           | giantg2 wrote:
           | There are a number of agricultural chemicals that we see as
           | being anecdotally harmful.
           | 
           | Heres a meta study concluding that glycophosphate exposure
           | can contribute to population reduction.
           | https://pubmed.ncbi.nlm.nih.gov/33636765/
        
       | clarionbell wrote:
       | This is possibly the first study demonstrating adverse Roundup
       | effects I've read that doesn't have any immediately obvious
       | issues. There could be some, obviously, but it's nothing like
       | using animal strains prone to cancer.
       | 
       | In this case the worms are mutants, but the strains are not noted
       | to be more prone to convulsions. They still had electrocute them,
       | but the time to recovery did seem to relate to chemicals
       | administered.
        
       | mattwest wrote:
       | These studies always bring out knee-jerk reactions in genpop, but
       | you have to understand what herbicides and GMO crops have done to
       | alleviate global hunger and malnutrition.
       | 
       | In the most developed countries, we spend 7-15% of our income on
       | food. The poorer you are, the higher that percentage is. In some
       | African countries, families will spend upwards of 70% of their
       | income for not just food, but for _bags of rice_. The bare
       | minimum.
       | 
       | In the past 4 decades, we've increased our crop yields by 4x.
       | This is because of intensive farming.
       | 
       | Now, is it destructive to the environment? Yes
       | 
       | Does it create fragility in our food systems and supply chains?
       | Yes
       | 
       | Should we immediately stop using herbicides and large-scale
       | monoculture systems? Think carefully about that one.
       | 
       | When people say, we need to implement regenerative agriculture,
       | or organic practices, or stop eating meat, etc, they _rarely_
       | have a full understanding of how our agrifood system works.
       | 
       | I'm an advocate for improving these systems, reducing herbicide
       | use, and implementing sustainable practices (whatever that means
       | at this point). But please, please, please try to fully
       | understand how our food system really works. Try to understand
       | the magnitude of cost reduction our current system has provided.
       | Try to understand how global life expectancy has increased by >20
       | years due to these practices.
        
         | wilburTheDog wrote:
         | Sri Lanka is an interesting case study. President Rajapaksa
         | suddenly banned using pesticides and synthetic fertilizers. It
         | caused significant reductions in crop yields and ended up
         | costing the country a great deal of money. This article in Vox
         | seems to cover it in a pretty balanced way
         | (https://www.vox.com/future-perfect/2022/7/15/23218969/sri-
         | la...).
         | 
         | I like organic farming. I use an organic approach for my home
         | garden. But yields are lower than with conventional farming.
         | Even the most positive studies agree on that (see
         | https://news.berkeley.edu/2014/12/09/organic-conventional-
         | fa...). It also takes more effort, which means more people
         | would have to be farmers than currently.
        
         | gopher_space wrote:
         | > These studies always bring out knee-jerk reactions in genpop,
         | but you have to understand what herbicides and GMO crops have
         | done to alleviate global hunger and malnutrition.
         | 
         | "I am too young to remember flipper babies."
         | 
         | To an older, educated portion of the 'genpop' your post is just
         | carrying water for Monsanto and has zero to do with GMO as a
         | concept. You've typed up a manifesto stating the obvious and
         | missing the point. Ask yourself why people would "oppose GMO"
         | if they agree with every point you make here.
        
         | Maursault wrote:
         | So it has nothing to do with maximizing profits and greed? Good
         | to know.
        
           | mattwest wrote:
           | Who said that?
        
           | malfist wrote:
           | That's a false dichotomy and you know it.
           | 
           | You can seek profit AND help make food less scarce at the
           | same time.
        
             | pretendscholar wrote:
             | ? The above comment never made that dichotomy. Interesting
             | that you took it that way.
        
           | bluGill wrote:
           | Maximum profit works best if you don't starve to death, and
           | thus continue eating year after year. Even better if you
           | decide you can afford to have a few kids (importantly feed
           | them)
        
         | tastyfreeze wrote:
         | I regularly advocate for regenerative agriculture. I have
         | studied and practiced, on a small scale, regenerative methods.
         | Pesticides and chemical fertilizers are not needed for the
         | abundance and we would be better off not using them. However,
         | the shift from chemical farming to regenerative practices
         | cannot be forced or rushed. It takes about 3 years to bring the
         | soil back to life and get it working as the plant's stomach and
         | yields to match or beat chemical farming. Forcing a change in
         | land management practices is a recipe for absolute disaster of
         | famine and likely war.
         | 
         | Due to the higher profitability of regenerative agriculture I
         | am confident that the majority of farms will shift to
         | regenerative in the decades to come. The only thing that can
         | stop the transition is government intervention to try to "save"
         | chemical farmers by subsidizing their chemical inputs. We just
         | have to stay out of the way and let the transition happen.
        
           | mattwest wrote:
           | Edible calories per acre per season are one thing. Labor cost
           | per acre are another, and that's the key element we need to
           | figure out if we want to transition. Right now the economics
           | don't work out.
        
             | metalliqaz wrote:
             | What makes the labor costs higher?
        
           | jjoonathan wrote:
           | > yields to match or beat chemical farming
           | 
           | Is it true? "Chemical farming" only happened because the
           | yields were better. Much better. What were farmers doing
           | wrong?
           | 
           | This sounds like another "we don't count fallow fields in the
           | divisor" hustle. I'd love to be wrong.
           | 
           | > Pesticides and chemical fertilizers are not needed
           | 
           | How do you control for herd immunity? One pesticide-free
           | field will never see a locust plague, a thousand pesticide-
           | free fields absolutely will.
           | 
           | > government intervention to try to "save" chemical farmers
           | by subsidizing their chemical inputs
           | 
           | Is this really an anti-intervention argument or is it an
           | attempt to frame the absence of steep fines on fertilizers
           | and pesticides as a subsidy?
        
             | tastyfreeze wrote:
             | Chemical farming happened because the bomb makers wanted to
             | continue selling ammonia and giving ammonia to plants does
             | make them grow big. But, it is a shortcut and destroys the
             | symbiotic relationship with the soil life. Initially the
             | soil still had a lot of organic matter and life in it and
             | it only took a small amount of fertilizer. After killing
             | the soil life there is no nitrogen, carbon, or phosphorus
             | cycle, the OM erodes away, and the remaining dirt becomes
             | compacted. As the soil degrades it has taken continually
             | more fertilizer to keep yields up.
             | 
             | Pesticides destroy the food chain. They kill pests and
             | their predators which makes it easier for the pests to
             | thrive. Predators keep pest populations in check but do not
             | eliminate them.
             | 
             | Fining the use of fertilizers and pesticides would be
             | disastrous. If fertilizers and pesticides are seen as the
             | sole way to grow all of our food the government will
             | absolutely try to step in and pay for a portion or all of
             | the fertilizers and pesticides as prices increase. This is
             | the only way that chemical farming will remain dominant. It
             | is simply becoming too costly to continue chemical farming.
             | 
             | Like I said before, the best course is to just let the
             | transition happen at the rate that it happens.
        
           | gruez wrote:
           | >Due to the higher profitability of regenerative agriculture
           | 
           | That might be true today, but will it hold into the future?
           | Organic agriculture is also more profitable than conventional
           | agriculture, even though it's less productive and has higher
           | costs. The only reason it's more profitable is that people
           | are willing to pay a premium for it. Obviously that's not
           | something that's scalable. You might be able to convince a
           | good chunk of bay area professionals to buy your
           | organic/regenerative agriculture crops at 3x prices, but once
           | you saturated that market you'll have much more trouble
           | convincing the rest of the country to into paying 3x (or
           | whatever) for their produce.
        
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