[HN Gopher] Salivary microbiome reveals a dysbiotic schizophreni...
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       Salivary microbiome reveals a dysbiotic schizophrenia-associated
       microbiota
        
       Author : bmau5
       Score  : 33 points
       Date   : 2022-08-02 18:45 UTC (4 hours ago)
        
 (HTM) web link (www.nature.com)
 (TXT) w3m dump (www.nature.com)
        
       | david_l_lin wrote:
       | Super interesting study! Other studies also associated the oral
       | microbiome with cognitive health, like depression and
       | Alzheimer's, but this is an interesting finding.
       | 
       | >H2S-producing bacteria exhibited disease-stage-specific
       | enrichment and could be potential diagnostic biomarkers
       | 
       | This would suggest that people with bad breath may have higher
       | risk of schizophrenia? Or maybe the reverse? I also wonder if
       | this was controlled for oral hygiene routines and oral health in
       | general? I would assume people with uncontrolled schizophrenia
       | have worse oral health, which may be a factor?
        
         | grawprog wrote:
         | This is anecdotal but, I used to know somebody with
         | schizophrenia. This person regularly took care of their teeth
         | but had pretty bad dental problems. Lots of cavities and gum
         | disease and such. Apparently they were even told by a dentist
         | at one point they just had 'bad bacteria' in their mouth and
         | would likely have tooth problems for the rest of their life.
        
         | BizarroLand wrote:
         | Makes me wonder what parts of your mental and emotional health
         | are mediated by your own breath?
         | 
         | Since the brain attenuates everything outside of the status quo
         | what portion of what it is spending energy attenuating is your
         | own malodorous exhalations?
         | 
         | How does the static labor of keeping your autonomous body on
         | cruise control affect your mental and emotional health? If we
         | could identify and control some of those things, how would
         | their presence or absence alter your mood and worldview?
        
       | cjbgkagh wrote:
       | Are Clinical High Risk people medicated? Because surely the
       | medicine would affect microbiota especially in the mouth.
        
         | david_l_lin wrote:
         | Majority were not on medication.
         | 
         | >Eighty-five FES patients and 35 CHR subjects were psychotropic
         | medication naive and all participants were free of substance
         | abuse, suicidal ideation, and unstable medical illness.
        
           | cjbgkagh wrote:
           | Thanks, that's what I was looking for.
        
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